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🧬 Why do some dangerous mutations stay silent while others strike? This fascinating Nature feature explores mutational buffering, especially the role of HSP90 and other heat-shock proteins in masking harmful variants, shaping disease risk, enabling tumour drug resistance, and even influencing evolution.

A sharp reminder that genotype is only part of the story—context, stress, and molecular chaperones matter too. 

🔥💊 #Genetics #PrecisionMedicine #CancerBiology #MedicalPodcasts