Traditional methodologies can not detect the majority of action occurring in complex protein assemblies such as focal adhesions. A new study applied a high throughput screen and multi-parametric analysis to identify genes implicated in focal adhesion formation. This biosights episode presents a paper by Winograd-Katz et al. in the Journal of Cell Biology and includes interviews with authors Sabina Winograd-Katz and Benjamin Geiger. Produced by Eun Choi and Aimee deCathelineau.
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