Dr. Harry Barbeeout of Johns Hopkins University recently co-authored ameta-analysisin JAMA Surgery, examining postoperative regret for those people seeking gender-affirming care. We talk about how many people *actually* regret receiving surgery, how that compares with general postoperative regret in the cisgender population, the politics and misinformation influencing the bad science in this area of study, and what we can do about it.