The Truth About Cholesterol, LDL, and Plaque Regression with Dave Feldman | Lean Mass Hyper-Responder Research Explained
What if everything you've been told about cholesterol and heart disease is incomplete — or even wrong?
In this eye-opening episode of The Coach Debbie Potts Show, I sit down with Dave Feldman, engineer turned citizen scientist, founder of Own Your Labs and The Citizen Science Foundation, and the mind behind the Lean Mass Hyper-Responder (LMHR) study and the groundbreaking Keto-CTA trial on plaque progression and regression.
We unpack the latest findings from Dave's multi-platform coronary imaging study — comparing HeartFlow, QAngio, Cleerly, and expert readouts — to explore how some individuals with very high LDL cholesterol and low inflammation show no increase in plaque and, in some cases, true regression.
You'll learn:
🧬 What the Lipid Energy Model reveals about metabolism and cholesterol transport
🩸 Why LDL-C and ApoB aren't always the villains — and when they actually matter
🧠 What "soft" vs. "hard" plaque really means for your risk
🩺 The best ways to measure and track plaque (CAC vs. CCTA vs. AI-based imaging)
⚡ How insulin resistance, inflammation, and oxidative stress drive true cardiovascular risk
🥑 Why many keto and low-carb athletes become "Lean Mass Hyper-Responders" — and what to do about it
Whether you're a clinician, health coach, or curious biohacker, this conversation will completely change the way you think about cholesterol, cardiovascular disease, and metabolic health.
00:00 – Intro & Dave Feldman bio
03:00 – The cholesterol paradox in metabolically healthy individuals
08:00 – The Lipid Energy Model explained
12:00 – What is plaque? (Soft vs. hard)
16:00 – How the Keto-CTA study tracked plaque regression
25:00 – The role of LDL, ApoB, and Lp(a) in context
33:00 – Imaging tools: CAC vs. CCTA vs. AI platforms
42:00 – Insulin resistance, inflammation, and endothelial damage
54:00 – Root cause solutions for cardiovascular health
Cholesterol is not the enemy — context and inflammation are.
The best way to manage heart disease risk is to measure plaque, not just LDL.
Metabolic health > cholesterol numbers when it comes to longevity.
Functional and nutritional therapy can stabilize or reverse soft plaque.
🌐 Website: www.DebbiePotts.net
🎧 Podcast: The Coach Debbie Potts Show
📺 YouTube: @CoachDebbiePotts
🧬 Learn about Root Cause Revolution™: www.rootcausedoc.com
🩺 Explore Own Your Labs: https://ownyourlabs.com
📚 Read more about the Keto-CTA study: https://citizensciencefoundation.org
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🧬 Seeking Health Supplements — Code COACHDEBBIEPOTTS
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#Cholesterol #DaveFeldman #HeartHealth #ApoB #LDL #PlaqueRegression #KetoDiet #MetabolicHealth #FunctionalMedicine #RootCauseRevolution #CoachDebbiePotts
