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It's a tale as old as time. Or the 60's, really.

Spider-Man's villains all team up to fight him. They call themselves the Sinister Six because it sounds cool (alliteration is ALWAYS cool). Then they have a million reunions because Spider-Man's not dead yet and why not?

We read the first two incarnations of the SS in Amazing Spider-Man Annual #1 and then in issues #334-339.

Come for the rogues' gallery, stay for Aunt May and Doc Ock flirting.

Next time: The Tick!