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Curiosity and necessity rewired research: how Navy oxygen studies led Dom D'Agostino to ketone biology and clinical translation. Edited down from 2 hours to 6 minutes, this condensed episode with host Peter Attia and guest Dom D'Agostino gives you the core insights fast. Learn the practical basics of the ketogenic diet and clinical ketosis (blood BHB >0.5 mmol/L), the differences between ketone salts, esters, and 1,3‑butanediol, and why D vs L beta‑hydroxybutyrate matters. Discover implementation tips—protein targets, electrolyte management, measurement, and safety caveats—and the current translational promise for epilepsy, glioblastoma, dementia, and controlled hyperbaric oxygen therapy. Keywords: ketogenic diet, ketosis, ketone salts, ketone esters, hyperbaric oxygen, cancer, dementia, epilepsy, biohacking. This is a pragmatic primer on dosing, formulation, and what the evidence really supports—listen now to get the key ideas in minutes.