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What if blood could reveal and even restore youthfulness in organs? In this 6-minute summary (original 2 hours), Andrew Huberman sits down with Dr. Tony Wyss‑Coray to unpack parabiosis, proteomic clocks, and translating mouse rejuvenation experiments into human therapies. Learn how blood proteins can serve as biomarkers and potential medicines, why exercise and liver-derived factors like clusterin matter for brain health, and which interventions—plasma fractions, plasma exchange, NAD precursors, and lifestyle changes—have the most evidence today. Hosts: Andrew Huberman; Guest: Dr. Tony Wyss‑Coray. Keywords: aging, proteomics, longevity, brain health, anti-aging research, plasma therapy, exercise, biomarkers. Listen now to get the key ideas and practical takeaways in minutes.