Over the past few weeks some really exciting papers came out describing the reprogramming of one cell into another, a process called Direct Reprogramming. On this episode we talk with Dr. Justin Ichida from USC who uses the latest reprogramming techniques in his lab to study neural disease. We review the literature from the past two weeks including increased brain activity in those that recall their dreams, incidence of Autism on the rise, converting skin cells into liver or pancreatic cells, and making meat from celebrities. We close with a rant on stir bars. Enjoy!
Justin Ichida completed his Ph.D. at Harvard Medical School in the laboratory of Dr. Jack Szostak. From 2007-2012, he was a postdoctoral fellow in the laboratory of Dr. Kevin Eggan in the Department of Stem Cell and Regenerative Biology at Harvard University. Dr. Ichida was a New York Stem Cell Foundation Druckenmiller Fellow and a recipient of the NIH K99/R00 Pathway to Independence award from the National Institute of Neurological Disorders and Stroke. Since 2013, he has been an Assistant Professor of Stem Cell Biology and Regenerative Medicine at the University of Southern California. His current research is focused on using patient-specific disease models to define the mechanisms that lead to neuronal loss in ALS and frontotemporal dementia.
Resources, Links and Research Papers Mentioned In This Session Include:
University of Southern California - The Ichida Lab – Board California Institute for Regenerative Medicine (CIRM) Center for Regenerative Medicine and Stem Cell Research
Research Papers:
Early Treatment Is Found to Clear H.I.V. in a 2nd Baby
Why Can You Remember Your Dreams? Researchers Uncover Why Only Some People Can Recall Them In The Morning
Acetaminophen In Pregnancy Linked To ADHD In Kids, Study Finds
Is It The Gluten Or Is It The Glyphosate?
Study Uncovers New Pathway Of Melanoma Metastasis
New Research Finds Direct Connection Between Acupuncture And Processes That Alleviate Sepsis
Largest Ever' Trial Of Adult Stem Cells In Heart Attack Patients Begins
This Company Wants To Make In-Vitro Meat From Celebrities’ Stem Cells
USPTO Issues Patent For Fraudulent Stem Cell Procedure
Isolation Of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors By Cell Sorting For Successful Transplantation
Coordination Of Engineered Factors With TET1/2 Promotes Early-Stage Epigenetic Modification During Somatic Cell Reprogramming
Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages
Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
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Photo Reference: Courtesy of Dr. Justin Ichida