Welcome back for another great episode of the SCP. Be sure to visit www.StemCellPodcast.com and enter your email address in to receive all the show notes and links to all the papers we discuss. We start as always with the science round up brought to you by Thermo Fisher Scientific. In this episode, we discuss the latest and greatest papers ranging from a repurposed over active bladder medication, what stem cell companies to invest in for 2015, a review of the latest iPSC reprograming methods, a new optogenetics study relating to Parkinson’s disease, the sequencing of the oldest mammals genome, and stem cells from the eye to repair damaged corneas. We then talk to Dr. David Piper about disease model tools. Yosif and I then close the show ranting about Parafilm. Enjoy!
Below are all of the papers mentioned on the show. We are working on a way to categorize all of the research papers we mention and possibly even provide audio summaries. Enter in your name and e-mail address below, and we will notify you of when this feature is available.
Resources, Links and Research Papers Mentioned In This Session Include:
Booze Binge Has Immediate Effect On Immune System – According to this article, alcohol can wreak havoc on your immune system from the moment you start imbibing.
BPA Alternative Disrupts Normal Brain-Cell Growth, Is Tied To Hyperactivity, Study Says – In this article, researchers have shown why the chemical bisphenol-S (BPS) once thought to be a safe alternative to bisphenol-A, which was abandoned by manufacturers of baby bottles and sippy cups after a public outcry, might itself be more harmful than BPA.
World First: Scientists Observe DNA Shuttling Between Cells, Triggering Tumor Growth – This article describes how a team of scientists observed that DNA from a mouse's second genome, or mitochondrial DNA, could be transferred from healthy tissue to tumor cells in mice, promoting cancer growth and spread.
Decline In Grants For Young Researchers Puts Future Of Science At Risk, Johns Hopkins President Writes – In this article, the president of John Hopkins University Ronald J. Daniels urges policy reforms and increased National Institutes of Health funding for young scientists who most of them are already leaving the academic biomedical workforce posing a grave risks for the future of science.
Teixobactin: Powerful New Antibiotic Kills Drug-Resistant Bacteria – In this article, a group of researchers led by Prof Kim Lewis of Northeastern University in Boston, Massachusetts, has discovered a new antibiotic Teixobactin that eliminates Methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium tuberculosis, Streptococcus pneumoniae, Bacillus anthracis and other dangerous pathogens without encountering any detectable resistance.
Weight Loss Drug Destroys Fat, Thanks To Bladder Medication: Finally A Treatment For Obesity? – This article describes how researchers figured out how FDA-approved drug mirabegron, typically used to treat overactive bladder, could boost brown fat’s metabolic burning efforts inside the body.
A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging – This article shows how scientists developed a protein scaffold, a repeating peptide array termed SunTag, which can recruit multiple copies of an antibody-fusion protein and may likely have many applications in imaging and controlling biological outputs.
Cold Virus Replicates Better At Cooler Temperatures – According to this article, researchers have found that the common cold virus can reproduce itself more efficiently in the cooler temperature found inside the nose than at core body temperature.
The Challenge Of Creating An HIV Vaccine: Virus Infects Very Cells Induced By Drug – This article tries to explain the reason why there is no vaccine for HIV/AIDS; it is because vaccines designed to protect against HIV backfire, leading to an increase, not decrease,
