Compared with mouse antibodies, rat monoclonal antibodies offer several advantages, including the reduced antigen requirement, the availability of using mouse antigens and greater lymphocyte yields. Moreover, rat antibodies pair better than that of mouse in sandwich assays: there is no cross reaction of available anti-mouse secondary antibody binding to the capture rat antibody.
http://www.creative-biolabs.com/Native-TM-Rat-Antibody-Discovery-Service.html
