Ubiquitination is a post-translational modification where ubiquitin, a small (8.5 kDa) regulatory protein, is attached to a substrate protein via an isopeptide bond. This process is carried out in three main steps (activation, conjugation, and ligation) by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. http://www.creative-biolabs.com/ubiquitination-specific-antibody-production-service.html
