The TCR is a molecule existed on the surface of T cells, or T lymphocytes. Its responsibility is to recognize fragments of antigen to provide peptides bound to major histocompatibility complex (MHC) molecules. Bispecific TCR molecules can leverage the body’s immune system by regulating the T-cell response towards cancer cells with specific tumor targets. There are two domains of our bispecific T-cell receptor. One of them is an affinity-maturated and highly selective TCR domain that can recognize and bind to a tumor-specific peptide target presented in the context of HLA class I receptor, the other is a T-cell recruiting antibody domain directed against CD3 or other immuno-modulating T-cell surface proteins. https://www.creative-biolabs.com/car-t/bispecific-tcr-development-service.htm
