San Francisco- 10 Buffalo- 35 BUF: Josh Allen- 13 out of 17 passes for 148 yards, two touchdown passes, a rushing touchdown and a touchdown reception Allen becomes the first player in NFL history to throw a touchdown pass, score a rushing touchdown and catch a touchdown pass in a single game. James Cook- 14 carries for 107 yards and a rushing touchdown SF: In the second quarter, running back Christian McCaffrey suffered an injury to his right knee. The injury happened after McCaffrey took a pitch from quarterback Brock Purdy where he barely moved with the ball before slowing to a limp, then sliding into the snow covered Highmark Stadium, avoiding contact and signaled for medical attention. It is feared that McCaffrey's injury could be season-ending. Philadelphia- 24 Baltimore- 19 PHI: Saquon Barkley- 23 carries for 107 yards and a rushing touchdown Tampa Bay- 26 Carolina- 23 overtime CAR: Bryce Young- 26 out of 46 passes for 298 yards, a touchdown pass and a rushing touchdown LA Rams- 21 New Orleans- 14 Arizona- 22 Minnesota- 23 Pittsburgh- 44 Cincinnati- 38 PIT: Russell Wilson- 29 out of 38 passes for 414 yards, three touchdown passes and an interception Tennessee- 19 Washington- 42 LA Chargers- 17 Atlanta- 13 Indianapolis- 25 New England- 24 Houston- 23 Jacksonville- 20 JAX: In the first half, quarterback Trevor Lawrence suffered a concussion after taking a nasty hit from a Jaguars defender. Seattle- 26 NY Jets- 21 SEA: Leonard Williams- recorded two sacks and scored an interception-return touchdown