In this episode of "BeeWellWithMS," we delve into the crucial topic of vaccinations for individuals living with Multiple Sclerosis (MS). Explore expert insights on the safety of vaccines, the effectiveness of vaccines while on Disease Modifying Therapies (DMTs), and the strategic timing of vaccinations to optimize your health.Discover when to schedule your vaccinations, taking into account disease activity and DMTs, with advice from a neurologist. Gain a better understanding of the differences between active attenuated and inactive vaccines, enabling you to make informed choices for your MS journey.Additionally, we explore how various DMTs can impact vaccine effectiveness and provide valuable guidance. Stay up-to-date with the latest developments and empower yourself with knowledge. Stay informed, empowered, and well with "BeeWellWithMS''. My website for keeping up to date with information: www.beewellwithms.com
vaccination and ms shownotes:
- Vaccinations and their impact on MS. 0:03
- Vaccines are not linked to increased MS relapses, with decades of confirmatory data.
- Inactive and attenuate live vaccines are safe for MS patients, with no increased risk of relapses.
- Vaccine safety in MS patients. 4:07
- New study finds no link between live vaccines and worsened MS symptoms.
- New term "immunogenicity" introduced to describe how well a vaccine stimulates the immune system to fight off disease.
- Vaccine effectiveness for MS patients on various therapies. 8:02
- Disease-modifying therapies may impair immunogenicity of vaccines, with varying degrees of impact depending on specific medications.
- Timing of vaccination is crucial for effective treatment of Multiple Sclerosis.
- Vaccine timing and efficacy for multiple sclerosis treatments. 11:39
- Timing of vaccination is crucial for optimal response and prevention of infection reactivation.
- Speaker 1 discusses potential impact of anti-CD20 therapy on vaccine efficacy, suggesting bridging therapies may be necessary to maintain vaccination schedule.
- Vaccinations for multiple sclerosis patients. 15:20
- Timing of vaccination crucial for optimal efficacy in MS patients, especially those on immunosuppressive therapies.
- Expert advises on vaccination strategies for MS patients, including bridging therapies and single dose strategies.
References:
Confavreux C. N. Engl J Med 2001
Grimaldi L et all. JAMA Neurol 2023
Otero- Romero S et al. MSJ 2023, Eur J Neurol 2023
Farez M. et Al Arch Neurol 2011
Papeix C Mult Scler 2021
Huttner A. Neurol Neuroimmunol Neuroinflamm, 2020
Carvajal et al p720 ECTRIMS 2023
Ciotti et al, MSRD 2020
Veloce study, Bar- Or et al, Neurology, 2020
Tortorella C Neurology, 2022
Susana Otero Romero, manuscript under preparation for publishing, ECTRIMS 2023 presentation Hep B and anti CD 20
Carvajal R et al, submitted JAMA Network Open
Gadani SP.Ebiomedicine,2021 Disanto G JAMA Neurol 2021
Carvajal R et al Mult Scler 2023
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