Fantasy football rankings have been shaken over the last few days, with injuries and late-season role changes hitting right in the heart of the playoffs.
According to FantasyPros, the biggest headline is Patrick Mahomes’ torn ACL and LCL, ending his season and forcing listeners to downgrade every Chiefs weapon, with Gardner Minshew now under center. That drop in passing efficiency pushes Chiefs wideouts and tight ends down weekly rankings and makes the running game more volume-dependent rather than explosive.
FantasyPros and Fantasy Six Pack both note that backfields have taken major hits. Houston’s Woody Marks left early with an ankle issue, and while he said he could have returned, his workload and explosiveness are now in question, softening his RB2 floor. Arizona’s Zonovan Knight was carted off and later placed on season-ending injured reserve, per Sharp Football’s injury tracker, which pushes Michael Carter and Emari Demercado into deeper-league flex consideration but caps the ceiling of the Cardinals’ run game.
FantasyPros also reports that Jacksonville rookie Bhayshul Tuten needs hand surgery and will miss several weeks. That vacates valuable touches in a high-scoring Jaguars offense and boosts any healthy back on that depth chart into strong flex or RB2 territory for the fantasy semifinals.
At wide receiver, FantasyPros notes Davante Adams pulled his hamstring late in Week 15 after already managing the injury all week. Sean McVay said he would not rule Adams out for Week 16, but most analysts are treating him as a long shot, pushing him down rankings and elevating his teammates in projected target share. Sports Illustrated highlights that the Falcons are optimistic Drake London can return from a four-game knee absence, which likely squeezes targets for tight ends and secondary receivers in Atlanta; that return nudges London back into WR2 range while capping the late-season rise of the Falcons’ TE.
Rome Odunze’s pregame foot setback, detailed by Fantasy Six Pack, means he’s now expected to miss at least one game, opening more volume for other Bears pass catchers and pulling Odunze out of startable consideration in most formats at the worst time.
NFL.com’s flex rankings for Week 16 reflect these shifts, pushing healthy, high-volume backs and receivers above injured stars who might be limited or out. Washington back Chris Rodriguez Jr. practicing in full, as reported by TheHuddle, is a small but notable positive; he’s back on the radar as a depth option in deeper leagues.
The overall effect for listeners: elite names like Mahomes and Adams slide down or off the board, emerging volume plays in Jacksonville, Arizona, and Atlanta move up, and savvy managers must re-evaluate every playoff lineup based on these late-breaking injuries and returns.
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