Risk factors Various risk factors raise the likelihood of developing TNBC. These include: Race: Black and Latinx people are more likely to receive a TNBC diagnosis than white people.Age: TNBC is more likely to present in people below the age of 50 years.Weight: Obesity increases the risk of receiving a diagnosis of TNBC.Genetic mutations: The BRCA1 gene mutation puts someone at higher risk of TNBC.