Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 32: Molecular Imaging (CT & PET) in RadOnc.In our previous episode, we explored the molecular tools that help us understand DNA damage, gene expression, and protein function. Today, we're moving from the lab bench into the clinic to see how some of these molecular principles are visualized and applied through advanced imaging techniques. We'll focus on Computed Tomography (CT) and Positron Emission Tomography (PET), discussing their physical principles, common contrast agents and radiotracers, and their crucial roles in cancer diagnosis, staging, treatment planning, and response assessment in radiation oncology.