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How much do we really know about depression? In this remastered episode, Gerard Sanacora, director of the Yale Depression Research Program and Co-director of the Yale Interventional Psychiatry Service, reveals that even doctors don't fully get the biological roots behind depression's mix of mental and physical woes. But that doesn't mean we don't have effective treatments — and those treatments are only getting better. For example, ketamine and psilocybin are being studied as unconventional treatments to reshape depressed brains. Tune in to learn how medicine moves forward in understanding this serious condition, even when the science isn't clear.Science Vs Ketamine episode: https://gimletmedia.com/shows/science-vs/5whmb8kvSee citations and a transcript here: https://tabooscience.show/03rerun-depression/Need music for a project? Use my Epidemic Sound referral link: https://share.epidemicsound.com/kbva2hConnect with the show: Newsletter: https://www.tabooscience.show/newsletter Instagram: https://www.instagram.com/tabooscience  YouTube: https://www.youtube.com/@tabooscience  Twitter: https://www.twitter.com/tabooscience  Website: https://www.tabooscience.show/  Loved this episode? Leave a review and rating here: https://podcasts.apple.com/us/podcast/taboo-science/id1533606473