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Description

Hirschprung's Disease, sometimes called congenital aganglionic megacolon, is the most common cause of neonatal bowel obstruction. It is due to an absence of ganglion nerve cells in the lower bowel. The absence of these cells leads to abnormal peristalsis so the aganglionic portion doesn't relax properly, effectively causing an obstruction. 

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(This isn't individual medical advice, please use your own clinical judgement and local guidelines when caring for your patients)