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Showing episodes and shows of
Amer Ghavanini
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Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Laser interstitial thermal therapy for mesial temporal lobe epilepsy
Laser interstitial thermal therapy (LITT) is an increasingly standard surgical tool for ablating epileptic foci, and the Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (LAANTERN) registry, representing the largest prospective multicenter cohort, aimed to describe seizure outcomes, procedural outcomes, and safety data for LITT in mesial temporal lobe epilepsy (MTLE). LITT was found to be well tolerated and effective for drug-resistant MTLE, showing clinically meaningful seizure outcomes and quality of life (QOL) improvements. At two-year follow-up, 58.4% of patients achieved Engel 1 outcomes (seizure-free or non-disabling auras) and 57.2% achieved International League Against Epilepsy (ILAE) 1/2 outcomes (seizure-free or rare...
2025-07-20
12 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Myasthenia Gravis Autoantibody Heterogeneity and Therapeutic Implications
This paper investigates the heterogeneity of autoantibodies in patients with myasthenia gravis (MG), focusing on their diverse pathogenic properties and temporal fluctuations. The researchers utilized advanced cell-based assays to analyze serum samples, revealing that different immunoglobulin isotypes (IgG, IgM, IgA) and IgG subclasses contribute to the disease through varying mechanisms like complement activation, receptor internalization, and acetylcholine binding site blocking. The findings suggest that a comprehensive understanding of each patient's unique autoantibody profile could lead to more personalized and effective therapeutic strategies for MG.
2025-07-20
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
VCP Multisystem Proteinopathy
Valosin-Containing Protein (VCP) myopathy, also known as Multisystem Proteinopathy (MSP1) or Inclusion Body Myopathy associated with Paget disease of bone and Frontotemporal Dementia (IBMPFD), is a complex, progressive, autosomal dominant adult-onset disorder caused by mutations in the VCP gene. The VCP protein, also called p97, is a highly conserved ATPase crucial for maintaining cellular protein homeostasis (proteostasis) through mechanisms like the ubiquitin-proteasome system (UPS) and autophagy, as well as other functions like membrane fusion and genomic integrity. Pathogenic mutations in VCP disrupt these processes, leading to the accumulation of ubiquitin-positive protein aggregates, a hallmark feature. The disease presents with...
2025-07-20
18 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Updated AAN Guidelines on prolonged disorders of consciousness
This comprehensive report from the American Academy of Neurology, in collaboration with the American Congress of Rehabilitation Medicine and the National Institute on Disability, Independent Living, and Rehabilitation Research, provides updated guidelines for managing prolonged disorders of consciousness (DoC) in both adults and children. It outlines diagnostic accuracy improvements, including the use of standardized assessments and multimodal evaluations, while emphasizing the importance of serial assessments due to fluctuating patient states. The document offers detailed prognostic recommendations, especially concerning traumatic versus non-traumatic injuries, and stresses the need for early family counseling regarding long-term care and disability. Finally, it addresses treatment approaches, notab...
2025-07-14
17 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Psychiatric comorbidities are an independent risk factor for unfavorable outcomes in Autoimmune Encephalitis
This article presents a multicenter cohort study examining the influence of comorbidities on outcomes and infectious complications in patients with autoimmune encephalitis (AE). The study analyzed data from 308 adult patients with common AE variants, identifying various preexisting conditions (PECs) and secondary diagnoses. Key findings indicate that psychiatric PECs are an independent risk factor for unfavorable outcomes, while severe infections during hospitalization, though common, were not associated with worse long-term results. The authors emphasize the need for integrated care and incorporating comorbidities into prognostic models for AE patients.
2025-07-14
12 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Timing of Anticoagulation for Stroke and Atrial Fibrillation
This systematic review and individual participant data meta-analysis of randomized controlled trials focuses on the optimal timing for initiating direct oral anticoagulants (DOACs) in patients who have experienced an acute ischemic stroke alongside atrial fibrillation. The study, known as CATALYST, analyzes data from four major trials (TIMING, ELAN, OPTIMAS, and START) to determine if starting DOACs early (within 4 days) significantly reduces the risk of recurrent stroke or hemorrhage. The findings suggest that early DOAC initiation is beneficial in reducing a composite outcome of recurrent ischemic stroke, symptomatic intracerebral hemorrhage, or unclassified stroke within 30 days without increasing the risk of bleedin...
2025-07-06
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Treating Small Vessel CNS Vasculitis: Early Intervention and Remission
This single-center retrospective cohort study investigates small vessel predominant primary CNS vasculitis (sv-PCNSV), a rare autoimmune disorder affecting brain and spinal cord blood vessels. Researchers analyzed data from 26 patients with biopsy-proven sv-PCNSV to understand their clinical features and the effectiveness of different treatments. The study compared an early intensive treatment (EIT) group receiving cyclophosphamide within three months of immunosuppression with an escalation treatment (ESC) group given initial glucocorticoids. Findings indicate that EIT was associated with a significantly shorter time to remission (5 months vs. 19 months), highlighting the importance of timely and aggressive treatment for this condition. While all patients in the EIT grou...
2025-07-06
16 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Neurofilament Light Chain Assays in MS Management
This review article from Neurology Neuroimmunology & Neuroinflammation, centers on the growing significance of neurofilament light chain (NfL) assays in managing multiple sclerosis (MS). It explains how NfL levels in blood can indicate neuroaxonal damage, offering a less invasive method than traditional MRI for predicting disease progression and monitoring treatment effectiveness in MS patients. While highlighting the potential of NfL as a prognostic and monitoring biomarker, the article also addresses current challenges in its widespread clinical application, such as the need for standardized measurements and established reference ranges, as well as the influence of confounding factors like age and other health condi...
2025-06-23
18 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Nucleoside reverse transcriptase inhibitor use and reduced risk of Alzheimer’s disease
This research article explores the potential link between nucleoside reverse transcriptase inhibitors (NRTIs), medications used for HIV and hepatitis B, and a reduced risk of Alzheimer's disease (AD). The authors hypothesize that NRTIs' ability to inhibit inflammasome activation, a process implicated in AD, contributes to this protective effect. Through a retrospective analysis of two extensive health insurance databases—the United States Veterans Health Administration and MarketScan—the study found a significantly lower incidence of AD in individuals exposed to NRTIs. The findings suggest a rationale for further clinical trials to investigate inflammasome inhibitors, like NRTIs or their less toxic derivatives...
2025-06-18
12 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Lipoprotein a and Stroke Recurrence: A Systematic Review
This paper is a systematic review and meta-analysis published in the Journal of Stroke concerning lipoprotein(a) and its relationship to stroke outcomes. The authors investigated the association of elevated lipoprotein(a) levels with stroke recurrence and functional outcomes in patients who have experienced ischemic stroke or transient ischemic attack. The study synthesized data from multiple studies, comprising over 17,900 patients, to conclude that higher lipoprotein(a) levels are significantly linked to increased stroke recurrence and poorer functional recovery. The research highlights lipoprotein(a) as a potential biomarker and therapeutic target for preventing subsequent strokes.
2025-06-15
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Serum NFL as a biomarker for CIDP Diagnosis and Treatment
This scientific study investigated the use of serum neurofilament light chain (sNFL), particularly when adjusted for age and BMI as z-scores (zNFL), as a biomarker for chronic inflammatory demyelinating polyneuropathy (CIDP). Analyzing a large cohort of patients with immune-mediated neuropathies, the researchers found that elevated zNFL correlated with increased disease severity in patients with typical CIDP, especially in the early stages of the illness. A zNFL score above 2 in the early phase of typical CIDP was associated with more severe motor dysfunction and a lack of response to initial standard treatments, suggesting that this biomarker could help identify patients needing more a...
2025-06-08
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Upadacitinib for Giant-Cell Arteritis, SELECT-GCA Trial Results
This is a research article from the New England Journal of Medicine detailing the findings of the SELECT-GCA clinical trial, which investigated a potential new treatment for giant-cell arteritis. The trial randomly assigned patients to receive either upadacitinib at different doses or a placebo, in combination with a glucocorticoid taper. The results indicated that a 15 mg dose of upadacitinib was more effective than placebo in achieving sustained remission and reducing glucocorticoid exposure. The study also reviewed the safety profile of upadacitinib in this patient population.
2025-06-04
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Assessing Functional Motor Weakness: A Practical Guide
This comprehensive review focuses on validated techniques used by clinicians to assess functional motor weakness, also known as functional neurological symptom disorder, which is a common presentation in neurology. The article discusses the importance of employing specific, studied examination methods to distinguish functional weakness from objective neurological weakness, which arises from structural or electrophysiological causes. Several diagnostic signs are described, including Hoover's sign, give-way weakness, the abductor sign, the abduction finger sign, the spinal injuries center test, motor inconsistency, drift without pronation, paradoxical wrist flexion, and the elbow flex-ex sign, detailing their techniques, interpretation, and limitations based on existing researc...
2025-06-01
21 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Treating Neuropsychiatric Symptoms in Parkinson's Disease
This paper serves as a comprehensive review of approaches for treating neuropsychiatric symptoms in Parkinson's disease (PD). It highlights that these non-motor symptoms are highly prevalent, significantly impair quality of life for both patients and caregivers, and often appear before motor symptoms. Despite recent advancements in diagnosis and management, treatment options, including both pharmacological and non-pharmacological therapies, remain limited due to the complex underlying brain changes in PD. The review summarizes current treatments for cognitive impairment, psychosis, depression, anxiety, apathy, and impulse control disorders, while also outlining ongoing research efforts to address the existing therapeutic gaps. Ultimately, the paper empha...
2025-06-01
20 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Rituximab Use in Anti-NMDAR Antibody-Mediated Encephalitis Relapse Prevention
This multicenter cohort study investigated the effectiveness of rituximab in preventing relapses in adult patients diagnosed with anti-NMDAR antibody-mediated encephalitis. Researchers evaluated the impact of a single course of rituximab on the time to first relapse and explored the duration of its effect, specifically at six and twelve months following treatment. The findings suggest that a single rituximab course is associated with a reduced risk of relapse, with the protective effect lasting for approximately six months. These results highlight the potential benefit of rituximab in managing this condition and suggest optimal redosing intervals for select patients.
2025-06-01
10 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Understanding Commercial Tissue-Based Assays for Autoimmune Neurologic Disorders
This episode combines two articles and discusses the importance of laboratory expertise in accurately diagnosing autoimmune neurological syndromes, particularly autoimmune encephalitis and paraneoplastic syndromes, which are often difficult to identify due to overlapping symptoms and low prevalence. The author reviews two companion studies evaluating commercially available tissue-based assays for detecting antibodies against intracellular and surface antigens. The studies reveal significant limitations in the sensitivity and specificity of these commercial tests when used as standalone screening tools, highlighting the risk of both false positives and false negatives. Ultimately, the piece emphasizes the need for multimodal testing, skilled interpretation of results, and interdisciplin...
2025-05-25
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Repeat Expansion Disorders in Neurology
This paper provides a comprehensive review of repeat expansion disorders, focusing on their significance in neurology. It explains how abnormal expansions of DNA repeats cause a wide range of neurological conditions, highlighting the diagnostic challenges and opportunities for management. The authors discuss the molecular characteristics of these disorders, including repeat size, location, and inheritance patterns, and detail the clinical features like anticipation and heterogeneity that can aid in diagnosis. Finally, the piece outlines the evolution and current state of genetic testing methods, emphasizing the increasing role of whole-genome sequencing and bioinformatics tools in detecting these complex genetic variations.
2025-05-23
16 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Neurological IgG4-Related Disease: Diagnosis and Management
This paper is a comprehensive review of IgG4-related disease (IgG4-RD) as it affects the nervous system. It discusses the clinical presentation, diagnosis, and treatment of this rare inflammatory and fibrotic condition, which can impact various parts of the nervous system, including the eyes, meninges, pituitary gland, brain parenchyma, and peripheral nerves. The article highlights the importance of early recognition and a high index of clinical suspicion due to the diverse ways IgG4-RD can manifest and mimic other conditions. While elevated serum IgG4 levels can be helpful, the paper emphasizes that histological confirmation is the gold standard for diagno...
2025-05-23
18 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Long-Term Ravulizumab Efficacy and Safety in Generalized Myasthenia Gravis
This paper presents the final findings from the extended phase of a clinical trial called CHAMPION MG, investigating the long-term effectiveness and safety of ravulizumab for adults with a specific type of myasthenia gravis characterized by antibodies against the acetylcholine receptor. The study followed patients for up to four years, including those who initially received ravulizumab and those who switched from placebo to ravulizumab. Results indicated sustained improvements in various measures of disease activity and quality of life for patients treated with ravulizumab. The research also highlights a significant reduction in corticosteroid use and clinical deterioration events among patients receiv...
2025-05-23
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
The Second European Carotid Surgery Trial (ECST-2)
This text summarizes interim results from the Second European Carotid Surgery Trial (ECST-2), a multicenter randomized trial comparing optimized medical therapy (OMT) alone versus OMT plus revascularization for patients with asymptomatic or low-to-intermediate risk symptomatic carotid stenosis of 50% or greater. The trial used the Carotid Artery Risk (CAR) score to identify patients predicted to have a 5-year stroke risk of less than 20%. The 2-year interim analysis, utilizing a hierarchical outcome and win ratio method, found no significant evidence that adding revascularization to OMT provided a benefit in this patient population. The study suggests that OMT alone might be sufficient for this...
2025-05-12
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Inebilizumab Trial in Myasthenia Gravis
Published in New England Journal of Medicine the study details the MINT trial, a phase 3 clinical trial evaluating the efficacy and safety of inebilizumab for treating generalized myasthenia gravis (MG). #Neurology #Myasthenia
2025-05-06
10 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Brain MRI as prognostic factor in Anti NMDA Encephalitis
Brain MRI pattern as prognostic factor in Anti NMDA Encephalitis #Neurology, #MS, #MRI
2025-05-03
10 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Efgartigimod Efficacy and Safety in CIDP - ADHERE and ADHERE+ Trials
Efgartigimod Efficacy and Safety in CIDP - ADHERE and ADHERE+ Trials #Neurology #CIDP #Efgartigimod
2025-05-02
10 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Telitacicept Shows Strong Efficacy for Generalized Myasthenia Gravis
Telitacicept Shows Strong Efficacy for Generalized Myasthenia Gravis
2025-04-28
07 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
C5 vs FcRn inhibitors for generalized myasthenia gravis
Comparison of C5 vs FcRn inhibitors for generalized myasthenia gravis #Neurology #Myasthenia
2025-04-28
07 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
MMF for anti-NMDA antibody maintenance
MMF for anti-NMDA antibody maintenance #Neurology
2025-04-28
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
European Guidelines for Assessment and Management of Neurogenic Bladder
This document presents new guidelines, called NEUROGED, developed by European and international neurological and urological societies to aid practicing neurologists in the assessment and management of urinary and sexual symptoms arising from neurological conditions. Employing a rigorous evidence-based approach, the guidelines offer recommendations for diagnosis, evaluation, and various treatment strategies, emphasizing a multidisciplinary perspective and highlighting when referral to specialist urological care is necessary. The ultimate aim is to improve the quality of care for individuals with neurological disorders experiencing these often-overlooked issues.
2025-04-20
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
ADVANCE CIDP -IVIG Clinical Trial
This research article from the European Journal of Neurology presents the results of the ADVANCE-CIDP IVIG trial, which investigated the effectiveness and safety of intravenous immunoglobulin 10% therapy (GAMMAGARD LIQUID/Kiovig) for treating relapses in adults with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). The study found that IVIG 10% was effective in treating CIDP relapses and improving functional abilities, with a high responder rate and a favorable safety profile in patients who had relapsed during a previous trial of subcutaneous immunoglobulin or placebo. These findings support the use of IVIG 10% as a rescue therapy for CIDP relapse, and contributed to its recent approva...
2025-04-20
07 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Multifocal Motor Neuropathy - A Comprehensive Review
Multifocal Motor Neuropathy - A Comprehensive Review
2025-04-12
25 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Bone marrow transplantation for MS, ECTRIMS Recommendation
Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder — recommendations from ECTRIMS and the EBMT
2025-04-12
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Do glucose lowering drugs prevent dementia?
Cardioprotective Glucose-Lowering Agents and Dementia RiskA Systematic Review and Meta-Analysis
2025-04-12
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Serum NfL as a Diagnostic and Prognostic ALS Biomarker
There are four serum NFL laboratory assays. Which one is the most accurate diagnostic and prognostic marker for ALS?
2025-04-06
08 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Stress and cryptogenic stroke in young adults
There is a link between stress and cryptogenic stroke in young adults.
2025-04-06
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Using AI Vision in Neurology
How can AI be used as an observation tool for diagnosis in Neurology.
2025-03-30
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
European Guidelines on PET imaging for brain metastasis
Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standard for PET imaging of brain metastases
2025-03-29
29 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Pyridostigmine for Orthostatic Hypotension
Pyridostigmine in the management of orthostatic hypotension: a systematic review and meta-analysis
2025-03-29
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
MoCA vs MMSE for Frontotemporal Dementia
Montreal Cognitive Assessment vs the Mini-Mental State Examination as a Screening Tool for Patients With Genetic Frontotemporal Dementia
2025-03-23
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Prognosis of Postanoxic Status Epilepticus
Postanoxic Status Epilepticus - Electrographic and Clinical Outcome Determinant
2025-03-23
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Idiopathic intracranial hypertension - diagnosis
Diagnosis process, misdiagnosis, and bias in suspected idiopathic intracranial hypertension
2025-03-23
08 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
rTMS Trial for Cognitive Impairment in ALS
rTMS Trial for Cognitive Impairment in ALS
2025-03-22
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Rozanolixizumab in Generalized Myasthenia Gravis - OLE
Rozanolixizumab Safety and Efficacy in Generalized Myasthenia Gravis, open label extension study
2025-03-22
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
CSF-Serum Free Kappa Light Chain Index - Optic Neuritis Diagnosis
The utility of CSF-Serum Free Kappa Light Chain Index in the diagnosis Optic Neuritis #Neurology
2025-03-16
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
ABN Guidelines on Multiple Sclerosis Disease-Modifying Treatment
ABN Guidance: Multiple Sclerosis Disease-Modifying treatment 2024
2025-03-15
10 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Neurological complications of immune checkpoint inhibitors
Neurological complications of immune checkpoint inhibitors: a practical guide
2025-03-15
23 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
TMPN Trial in ALS
TMPN Trial in Amyotrophic Lateral Sclerosis: A Phase 2 Study
2025-03-13
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
A Practical Approach to the Diagnosis of Neuropathies
A Practical Approach to the Diagnosis of Neuropathies
2025-03-13
22 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Therapeutics in Inflammatory Muscle Diseases
Emerging mechanisms and therapeutics in inflammatory muscle diseases
2025-03-09
18 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Treatment of Cluster Headaches
Treatment of Cluster Headaches #Neurology #Headache
2025-03-09
36 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Clinical Trial of Zilucoplan in ALS
Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis A Randomized Clinical Trial
2025-03-09
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Is Multiple Sclerosis a Virus-Induced Gliopathy?
Is Multiple Sclerosis a Virus-Induced Gliopathy?
2025-03-08
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
DDPX Antibody Associated Encephalitis - A Review
Clinical and Paraclinical Characterizations, Management, and Prognosis in DPPX Antibody-Associated Encephalitis
2025-03-05
19 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Antidepressant use and cognitive decline in patients with dementia: a national cohort study
Antidepressant use and cognitive decline in patients with dementia: a national cohort studyhttps://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-03851-3
2025-03-02
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Cost of New Neurologic Medications
Cost Trends of New-To-Market Neurologic Medications
2025-03-01
26 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
rTMS and Aphasia Therapy Post-Stroke, a Clinical Trial
Transcranial Magnetic Stimulation Combined With Multimodality Aphasia Therapy for Chronic Poststroke Aphasia
2025-03-01
23 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Periodic EEG Patterns
Periodic EEG Patterns: Recognition and Clinical Significance.
2025-02-24
10 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Acceptance and Commitment Therapy
Acceptance and Commitment Therapy: Enhancing Psychological Well-Being
2025-02-24
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Endovascular therapy versus best medical care for acute ischemic stroke with distal medium vessel occlusion
Endovascular therapy versus best medical care for acute ischemic stroke with distal medium vessel occlusion: a systematic review and meta-analysis
2025-02-23
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Exenatide in Parkinson’s disease phase 3 trial
Exenatide once a week versus placebo as a potential diseasemodifying treatment for people with Parkinson’s disease in the UK: a phase 3, multicentre, double-blind, parallel-group, randomised, placebo-controlled trial #Neurology #Parkinson
2025-02-23
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
No long‑term benefits from resistance training on brain grey matter volumes in active older adults at retirement age
No long‑term benefits from resistance training on brain grey matter volumes in active older adults at retirement age #Neurology
2025-02-23
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Tirofiban Efficacy in Stroke
Tirofiban Efficacy in Stroke
2025-02-09
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
International Consensus Guidance for Managing Glucocorticoid-Related Neuromuscular Complications
International Consensus Guidance for Managing Glucocorticoid-Related Neuromuscular Complications #Neurology #Neuromuscular Disorders #Glucocorticoid
2025-02-09
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Consensus Statement on Continuous EEG in Critically Ill Patients
From 2015 The Critical Care Continuous EEG Task Force of the American Clinical Neurophysiology Society Consensus Statement on Continuous EEG in Critically Ill Patients
2025-02-02
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
AI-Optimized Anti-Seizure Treatment and EEG in Brain Injury
AI-Optimized Anti-Seizure Treatment and EEG in Brain Injury. How to use AI to optimize treatment of seizure. #Neurology #EEG
2025-02-02
21 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
MOG Antibody Testing in Clinical Practice
MOG Antibody Testing in Clinical Practice - Exploring when to order and how to interpret the results of this test. #Neurology #MS #MOG #Neuroimmunology
2025-02-02
22 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
LUMINESCE A phase 3 trial clinical trial of satralizumab for generalized myasthenia gravis
LUMINESCE A phase 3 trial clinical trial of satralizumab for generalized myasthenia gravis #Nerology #Clinical Trial #Neuromuscular Disorders #Myasthenia gravis
2025-02-02
19 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Lipid Variability and Cognitive Decline in Older Adults
Lipid variability and cognitive decline in older adults #Neurology #Alzheimer's disease #Dementia
2025-02-02
12 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Blood Biomarkers and MS Diagnosis
Blood Biomarkers and MS Diagnosis #MS #Neurology #Biomarkers
2025-02-02
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Long-Term Ocrelizumab Treatment for Early-Stage Relapsing MS
Long-Term Ocrelizumab Treatment for Early-Stage Relapsing MS #Neurology #MS #Ocrelizumab
2025-02-02
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
The Spectrum of Genetic Risk in Alzheimer's Disease
The Spectrum of Genetic Risk in Alzheimer's Disease #Neurology #Alzheimer's disease #Genetics
2025-02-02
19 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Central Nervous System Manifestations in Sjögren's Disease
Central Nervous System Manifestations in Sjögren's Disease #Neurology #Sjogren's disease
2025-01-26
23 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Intravenous Thrombolysis for Minor Stroke - A Systematic Review and Meta-analysis
Intravenous Thrombolysis for Minor Stroke - A Systematic Review and Meta-analysis #Neurology #Stroke
2025-01-26
17 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Cancer risk in multiple sclerosis patients and DMT
Cancer risk in multiple sclerosis patients and DMT #Neurology #MS
2025-01-26
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Neurogenic Orthostatic Hypotension in Parkinson's Disease
Neurogenic Orthostatic Hypotension in Parkinson's Disease #Neurolog #Parkinson's disease
2025-01-26
35 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Cognitive decline after heart failure
Cognitive decline after heart failure #Neurology #Dementia #Heart failure
2025-01-26
11 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Friedreich Ataxia: A 30-Year Retrospective
Friedreich Ataxia: A 30-Year Retrospective #Neurology #Friedreich Ataxia
2025-01-20
23 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Breaking Bad News in ALS/MND: The A-L S-PIKES Protocol
Breaking Bad News in ALS/MND: The A-L S-PIKES Protocol #Neurology #ALS
2025-01-19
21 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Plasma Neurofilaments as ALS Biomarkers
Plasma Neurofilaments as ALS Biomarkers #Neurology #ALS #Biomarker
2025-01-19
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
APOE's Role in Cerebral Amyloid Angiopathy
APOE's Role in Cerebral Amyloid Angiopathy #Neurology #Alzheimer's disease #dementia
2025-01-19
28 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Intra-arterial Tenecteplase After Posterior Circulation Recanalization - ATTENTION-IA trial
Intra-arterial Tenecteplase After Posterior Circulation Recanalization - ATTENTION-IA trial #Neurology #Stroke #Tenecteplase
2025-01-18
07 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
WHO Classification of Central Nervous System Tumors, Fifth Edition - A flashback to 2021
WHO Classification of Central Nervous System Tumors, Fifth Edition - A flashback to 2021 - #Neurology, #Neurooncology #Brain #Brain Tumors #Central Nervous System Tumors
2025-01-16
32 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Tele-EEG for Critically Ill Patients: A Multicenter RCT
Tele-EEG for Critically Ill Patients: A Multicenter RCT. Key words: Epilepsy, Neurology, EEG, ICU, EEG monitoring
2025-01-12
19 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Anti-IgLON5 Disease: A Decade of Discovery and Unanswered Questions
Anti-IgLON5 Disease: A Decade of Discovery and Unanswered Questions - Neurology, Neuroimmunology
2025-01-11
16 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Ravulizumab and Efgartigimod in Myasthenia Gravis: A Real-World Study
Ravulizumab and Efgartigimod in Myasthenia Gravis: A Real-World Study - Keywords: Myasthenia Gravis, Treatment, Neurology, Neuromuscular Disorders, Ravulizumab, Efgartigimod
2025-01-11
14 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Autoimmune Nodopathies and IgG4 Antibodies in Neurology
Autoimmune Nodopathies and IgG4 Antibodies in Neurology - Keywords: Neurology, CIDP, GBS, Neuropathy, Nodopathy
2025-01-11
17 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
SAHARA Trial: Transfusion Strategies in Aneurysmal Subarachnoid Hemorrhage
SAHARA Trial: Transfusion Strategies in Aneurysmal Subarachnoid Hemorrhage. Keywords: Neurology, Stroke, Aneurysm, Neurosurgery, Vascular Neurosurgery, Vascular Neurology
2025-01-11
08 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
CRISPR-Cas9 Gene Editing for ATTR Cardiomyopathy
CRISPR-Cas9 Gene Editing for ATTR Cardiomyopathy - Keywords: Neurology, ATTR, Neuromuscular Disorders, Gene Therapy
2025-01-11
19 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Introduction to Weekly Deep Dive Neurology Podcast
Introduction to Weekly Deep Dive Neurology Podcast
2025-01-05
03 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Memantine in Amyotrophic Lateral Sclerosis
Memantine in Amyotrophic Lateral Sclerosis - Keywords: Neurology, ALS, Memantine, Clinical Trial, Neuromuscular Disorders
2025-01-04
24 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Rituximab for Idiopathic Inflammatory Myositis: A Systematic Review and Meta-analysis
Rituximab for Idiopathic Inflammatory Myositis: A Systematic Review and Meta-analysis - Keywords: Neurology, Myositis, Neuromuscular Disorders, Rheumatology
2025-01-04
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Vutrisiran for ATTR cardiomyopathy
Vutrisiran for ATTR cardiomyopathy - neuropathy
2025-01-04
06 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Long-Term Safety of fSCIG for CIDP Maintenance Therapy
Long-Term Safety of fSCIG for CIDP Maintenance Therapy - Keywords: CIDP, IVIg, SCIG, Neurology, Neuropathy, Neuromuscular Disorders
2025-01-04
20 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Neurofilament Light Chain and GFAP in Mood and Anxiety Disorders
Neurofilament Light Chain and GFAP in Mood and Anxiety Disorders. Keywords Anxiety, Depression, Neurology, Psychiatry, Neuropsychiatry
2025-01-04
15 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Efficacy and Safety of IVIG Maintenance Therapy in Generalized Myasthenia Gravis
Efficacy and Safety of IVIG Maintenance Therapy in Generalized Myasthenia Gravis. Keywords: Myasthenia Gravis, Neurology, IVIg, Maintenance, Trial
2025-01-04
09 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Anticoagulation strategy for patients presenting with ischemic strokes while using a direct oral anticoagulant:
Anticoagulation strategy for patients presenting with ischemic strokes while using a direct oral anticoagulant: #Neurology #Stroke
2025-01-04
13 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Early Atogepant Efficacy in Migraine Prevention
Early Atogepant Efficacy in Migraine Prevention
2024-12-29
28 min
Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
2024 AASM Clinical Practice Guideline: Restless Legs Syndrome and PLMD Treatment
2024 AASM Clinical Practice Guideline: Restless Legs Syndrome and PLMD Treatment
2024-12-29
15 min