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Showing episodes and shows of
Anne Chappelle, PhD, DABT
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Adverse Reactions
Testing the Waters
From studying polluted waters off the coast of California to explaining the feasibility of a fungal-based zombie outbreak at San Diego Comic Con, Kari Sant, PhD, Michigan State University, discusses her passion projects with co-hosts Anne Chappelle, PhD, DABT, and David Faulkner, PhD, DABT. Dr. Sant also reveals what it is like to start a new lab when you change institutions.About the GuestKari Sant, PhD, is an Associate Professor of pharmacology and toxicology in the College of Veterinary Medicine at Michigan State University. She received her Bachelor of Science in biology and...
2025-01-13
26 min
Adverse Reactions
Boom! When Evolutionary Biology and Toxicology Collide
Noah Whiteman, PhD, a professor at UC Berkeley, shares his unique perspective on toxins, stemming from his background in entomology and plant-insect interactions. He explores how toxins impact the ecology and evolution of various organisms, from insects to humans, with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.About the GuestNoah Whiteman, PhD, is Professor of Genetics, Genomics, Evolution, and Development in the Department of Molecular & Cell Biology and the Department of Integrative Biology at University of California (UC) Berkeley. His laboratory focuses on understanding why and how organisms deploy toxins as weapons...
2025-01-06
28 min
Adverse Reactions
Cardiovascular Risks from Low-Level Metal Mixtures
Sometimes negative results can be just as interesting as positive ones. Nivetha Subramaniam, a student at McGill University, discusses her research regarding the potential cardiovascular risks from exposure to mixtures of arsenic and cadmium with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.About the GuestNivetha Kamalavannan Subramaniam is a PhD student at McGill University in Canada. She is the recipient of the McGill Dr. Morris Karmazyn and Dr. Margaret P. Moffat Fellowship in Cardiovascular Research. The title of her PhD thesis project is "The Pro-atherogenic Effects of Arsenic and Cadmium Mixtures."
2024-12-30
27 min
Adverse Reactions
Tox in Your Backyard
From Superfund remediation sites near neighborhoods to wartime combat zones, toxicology is everywhere, which is why many states employ toxicologists on their public health teams. Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, speak with Julie Miller, PhD, Public Health Toxicologist for the Commonwealth of Pennsylvania, about the impacts of stress and environmental exposures on public health.About the GuestJulie Miller, PhD, Public Health Toxicologist, Pennsylvania Department of Public Health, is a board-certified toxicologist with primary training and expertise in analytical chemistry, in vitro and alternative methods, toxicology study design, data analysis and...
2024-12-23
27 min
Adverse Reactions
Toxicology Is a Team Sport: The Science of Working Together
Did you know that there are scientists who study teamwork? Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, DABT, speak with Stephen Fiore, PhD, Director, Cognitive Sciences Laboratory, about the art and science of working in teams and what you can do to improve teamwork in your lab, department, etc.About the GuestStephen M. Fiore, PhD, is Director, Cognitive Sciences Laboratory, and Professor with the University of Central Florida's Cognitive Sciences Program in the Department of Philosophy and School of Modeling, Simulation, and Training. He maintains a multidisciplinary research interest that incorporates aspects...
2024-12-16
26 min
Adverse Reactions
Pipping the Scales with Zebrafish
Fish on treadmills? Lisa Truong, PhD, MBA, Oregon State University, discusses the unique ways that they test exposure effects using zebrafish. Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, also ask her about the benefits of having an MBA as a scientist.About the GuestThe overall goal of Lisa Truong's research program is to utilize the zebrafish model to help build computational predictive toxicity models. Secondarily, she aims to move the field to be less reliant on animal testing and to conduct toxicity-testing based on toxicity pathways. Dr. Truong has a...
2024-12-09
25 min
Adverse Reactions
Snow Big Deal? Similar Exposures, Different Outcomes
Can two people experience the same exposure and have different reactions to both chemical and non-chemical stressors? Yes, according to Samantha "Sam" Snow and a team of toxicologists, epidemiologists, exposure scientists, and others who assess risk. Dr. Snow talks with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, about exposure science, new approach methodologies, and forming the SOT Out Toxicologists and Allies Special Interest Group.About the GuestSamantha Snow, PhD, DABT, is a Director of Toxicology at ICF specializing in risk assessment projects, toxicological and epidemiological study summaries and reviews, literature reviews, technical...
2024-12-02
27 min
Adverse Reactions
High Intensity Sweeteners with a Sugar Czar
Whether its found in nature or composed by chemists a sweetener undergoes the same evaluations, according to Corey Scott, PhD, Principal Nutritionist, Cargill. Dr. Scott explains to co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, how all sweeteners must be able to replace multiple properties inherit in sugar, such as taste, nutritional content, and binding properties.About the GuestCorey Scott, PhD, is a Principal Nutrition Scientist with Cargill in Minneapolis, Minnesota, where he leads global nutritional research on sweeteners and carbohydrates. Prior to this role, he was Global Nutrition Manager for Lipid Nutrition...
2024-11-25
28 min
Adverse Reactions
Little Zombie Parasites
Co-hosts Anne Chappelle and David Faulkner speak with William J. Sullivan, PhD, Showalter Professor of Pharmacology & Toxicology and Professor of Microbiology & Immunology with the Indiana University School of Medicine, about toxic parasites lying dormant in your brain and the power and importance of science communication.About the GuestBill Sullivan, PhD, has been studying the intracellular parasite Toxoplasma gondii since he was a graduate student in the laboratory of Dr. David Roos at the University of Pennsylvania in 1994. He completed postdoctoral fellowships with Dr. Chuck Smith at ELANCO (a division of Eli Lilly, Co...
2024-11-18
37 min
Adverse Reactions
Pitfalls in Pharmaceutical Production: Protecting the Actual Drug Makers
While pharmaceuticals provide positive benefits for patients, what about workers that may be exposed during production? Elizabeth M. Vancza, Merck & Co. Inc., reveals to co-hosts Anne Chappelle and David Faulkner the role of occupational toxicologists in understanding the exposure risks of pharmaceuticals, chemicals, and other substances that may affect worker health, as well as how to protect them from these exposures.About the GuestElizabeth M. Vancza, PhD, DABT, is currently an Associate Director of Occupational Toxicology at Merck & Co. Inc., where she assists business operations in the areas of occupational toxicology, potent compound...
2023-07-27
23 min
Adverse Reactions
Bringing Cohorts in Cahoots with Lab Science
The fields of epidemiology and toxicology sometimes find themselves at odds, but Gradient’s Julie Goodman, an epidemiologist and toxicologist, shares how the two disciplines can complement each other to evaluate public health risks. Dr. Goodman also dives into the finer points of systemic reviews and meta-analyses in her conversation with co-hosts Anne Chappelle and David Faulkner.About the GuestJulie E. Goodman, PhD, DABT, FACE, ATS, is an epidemiologist and board-certified toxicologist with over 20 years of experience. She is a Principal with Gradient and applies her multidisciplinary expertise to evaluate human health risks ass...
2023-07-06
31 min
Adverse Reactions
The Delicious World of Food Safety
Even chocolate companies and wineries need toxicologists. Alexandria G. Lau, ToxStrategies Inc., has worked for both and shares her experiences with co-hosts Anne Chappelle and David Faulkner. They also discuss the research and development that goes into new food products and how toxicologists play a role in food safety.About the GuestAlexandria G. Lau, PhD, DABT, ToxStrategies Inc., is a toxicologist with a decade of experience in the food and beverage industry. She has extensive knowledge of global regulations related to consumer products, including pesticides (US Environmental Protection Agency), food and packaging (US...
2022-04-07
26 min
Adverse Reactions
Space, the Final Risk Assessment Frontier
How do you set exposure limits to protect human health in a closed container floating in space? Valerie Ryder, a toxicologist at the NASA Johnson Space Center, takes co-hosts Anne Chappelle and David Faulkner into the small world of space toxicologists, where they also discuss research involving lunar dust, bone loss, and CO2.About the GuestValerie Ryder, PhD, DABT, is a board-certified toxicologist with the NASA Johnson Space Center. She received a BA in chemistry with a minor in microbiology from Texas A&M University in 2000 and a PhD in pathology from the...
2022-03-10
35 min
Adverse Reactions
More Than a Color Scheme: The Future of Toxicology in Green Chemistry
Margaret “Meg” H. Whittaker, Managing Director and Chief Toxicologist of ToxServices LLC, outlines the similarities and differences between risk assessment, alternative assessments, and green chemistry. Co-hosts Anne Chappelle and David Faulkner also discover how alternative assessments can lead to safer and more sustainable products that protect animal, human, and environmental health and the importance of diversifying your portfolio when you’re a student or early career researcher. About the GuestMargaret H. Whittaker, PhD, MPH, CBiol, FRSB, ERT, DABT, has over 20 years of experience in both the performance and management of toxicol...
2021-05-20
24 min
Adverse Reactions
The United States of Toxicity
Retired National Institute of Environmental Health Sciences (NIEHS) Director and lifelong federal scientist Linda S. Birnbaum discusses the intersection of policy and science, as well as the effect of environmental exposures on public health, with co-hosts Anne Chappelle and David Faulkner. Dr. Birnbaum also shares her insights on how to be an effective leader and the importance of mentorship. About the GuestLinda S. Birnbaum, PhD, DABT, ATS, is the former Director of the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH), and the National To...
2021-04-29
26 min
Adverse Reactions
Capturing Adverse Reactions
Meet co-hosts Anne Chappelle and David Faulkner as they explore the origins of Adverse Reactions, how people are at the heart of all science, and why the science of toxicology is more relevant than ever. About AnneAfter graduating from the University of Delaware with a BS in biology in 1991, Anne Chappelle accidentally found her calling when she worked a gap year in an industrial toxicology laboratory. As it turned out, toxicology was the perfect marriage of protecting both human health and the environment. She then went on to receive her PhD in...
2021-04-22
09 min