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Showing episodes and shows of
Austin Rupp
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Last Week in Medicine
Semaglutide for CVD in Diabetes, PAD, and MASH, Semaglutide vs Tirzepatide, Normal Saline vs Lactated Ringer's, Oxygen Targets for Intubated Patients, Platelet Transfusion Guidelines, Apixaban vs Rivaroxaban
Today we do a round-up of some of the recent semaglutide trials. Does semaglutide ever miss? But what about tirzepatide, which causes even more weight loss?We also review two new critical care trials, FLUID and the UK-ROX, new platelet transfusion guidelines, and a new retrospective study of apixaban vs rivaroxaban vs warfarin. Oral Semaglutide for Diabetes with Cardiovascular Disease or CKD (SOUL)Semaglutide for Peripheral Artery Disease (STRIDE)Semaglutide for MASH (ESSENCE)Semaglutide vs Tirzepatide for Obesity (SURMOUNT-5)Normal Saline vs Lactated Ringers (FLUID)C...
2025-06-17
1h 05
Last Week in Medicine
Hydrocortisone for Severe Pneumonia (REMAP-CAP), Intensive BP Control in Diabetes (BPROAD), Aldosterone Synthase Inhibitors for Hypertension (ADVANCE-HTN), Reduced-dose Apixaban for Cancer Associated Thrombosis (API-CAT)
What do you do when most trials suggest benefit for an intervention, but then a new trial suggests harm? We thought steroids in pneumonia was a settled question, but REMAP-CAP had other plans!We also review a new RCT for BP targets in patients with hypertension and diabetes, a new aldosterone synthase inhibitor for hypertension, and reduced dose apixaban for cancer-associated thrombosis. Hydrocortisone for Severe CAP (REMAP-CAP)Predicting Benefit of Corticosteroids in PneumoniaIntensive BP Control in Patients with Diabetes (BPROAD)Lorundrostat for Uncontrolled Hypertension (ADVANCE-HTN)Reduced D...
2025-04-25
56 min
Catalyst Conversations
Data Center World Recap With Kinetics And Noise Barriers
This episode recaps the Data Center World tradeshow in Washington, DC., where Kinetics Noise Control and Noise Barriers exhibited. We are joined by John Sofra and Jerry Davis from Kinetics, and James Thomas and Austin Rupp from Noise Barriers.To learn more about Kinetics, please visit https://kineticsnoise.com/To learn more about Noise Barriers, please visit https://www.noisebarriers.com/
2025-04-24
22 min
Last Week in Medicine
Half Dose DOAC for Long Term VTE Prevention, Biomarker Guided Antibiotics for Sepsis, GPT-4 Assistance for Physicians, Optimal Vasopressin Initiation for Shock, DOAC vs No AC for A fib After Intracerebral Hemorrhage, HFNC vs NIV for Respiratory Failure
For this episode we are joined by EBM guru, Dr. Brian Locke, who deftly breaks down all of our statistics questions. Is half dose DOAC as good as full dose DOAC for preventing VTE, and does it reduce bleeding risk? Can procalcitonin reduce duration of antibiotics for infections without compromising mortality rates? Can LLMs like GPT-4 help physicians manage patients better? Can reinforcement learning models predict when to start vasopressin in patients with septic shock? What is the risk of resuming anticoagulation in patients with atrial fibrillation and prior intracerebral hemorrhage? Is high flow nasal cannula as g...
2025-03-27
1h 32
Hawgs on the Hill
Hawgs on the Hill | Razor Recap: Calipari Stuns Wildcats in Return to Rupp
Join Caleb and Austin as they recap Coach Cal and Arkansas pull off an amazing win in Cal's return to Rupp. Plus, they recap Arkansas Gymnastics falling on the road to #1 Oklahoma. And finally, they breakdown the second weekend of scrimmages of the season for Arkansas Baseball! So, tune in and join the chat!
2025-02-08
1h 22
Last Week in Medicine
7 vs 14 Days of Antibiotics for Bacteremia, Factor XI Inhibition for Atrial Fibrillation, ACEi or ARB Before Elective Surgery, GLP-1 Agonist for HFpEF and Obesity
We're back, after a brief hiatus! Today we talk about duration of therapy for bacteremia, Factor XI inhibition for atrial fibrillation, whether to stop ACEi or ARB before elective surgery, and whether GLP-1 agonists are beneficial in heart failure with preserved ejection fraction. Go to minute 7:30 to skip the banter. 7 vs 14 Days of Antibiotics for Bacteremia (BALANCE)Abelacimab vs Rivaroxaban for Atrial Fibrillation (AZALEA-TIMI-71)Asenduxian vs Apixaban for Atrial Fibrillation (OCEANIC-AF)ACEi or ARB Discontinuation Before Surgery (STOP or NOT)Tirzepatide for HFpEF and Obesity (SUM...
2025-02-07
1h 06
College Basketball Show With Jim Dunaway and Taylor Korn
PREVIEW: Alabama Basketball vs Arkansas | Is Alabama Meeting Arkansas At The WORST Possible Time?
Coming off a win over Georgia and a mid-week bye, Nate Oats and Alabama go on a 2-game stretch of road matchups at Arkansas and Texas before returning back to Coleman Coliseum to host Auburn. John Calipari and the Razorbacks had a rough start to conference play but are on a 2-game win streak after beating Kentucky in Rupp Arena and Texas in Austin. Alabama is unbeaten on the road so far in SEC play but will be playing in a hostile environment in Bud Walton Arena on Saturday night as the Hogs return to Fayetteville after a successful...
2025-02-07
05 min
Locked On SEC – Daily College Football & Basketball Podcast
John Calipari's Return: How Arkansas Stunned Kentucky in Rupp; Bama Hires Ryan Grubb as OC
John Calipari's Arkansas Razorbacks upset the Kentucky Wildcats 89-79 in Cal's return to Rupp Arena. Arkansas shot 52% from 3, with all 5 starters in double digits. Kentucky's defense struggled, with no answer for the Hogs' hot shooting. Cal even admitted looking at the wrong scoreboard out of habit. What do you think this win means for Arkansas' season? Also, former Wildcat Reed Sheppard shows support for his former coach, wearing an Arkansas shirt. Should Sheppard show allegiance to the school and where he grew up, over his coach? On the football side of things, Alabama hired Ryan Grubb as o...
2025-02-03
29 min
Hawgs on the Hill
Hawgs on the Hill | Episode 36 Coach Cal Returns to Rupp/Arkansas Infield Breakdown
Tonight, on Hawgs on the Hill, Caleb and Austin will be joined by Jay Hazze from Religiously Kentucky Sports to talk about Coach Cal's return to Rupp Arena. Then RazorbackHobbs will join us to break down the Arkansas Baseball infield. Plus, they update you on all things transfer portal. Join us and let us know your thoughts!
2025-02-01
1h 31
Bandana Blues, founded by Beardo, hosted by Spinner
Bandana Blues #1071 - Mixing New With Older
Show #1071 Mixing New With Older 01. Fo'Reel - Tator (4:37) (Heavy Water, self-release, 2014) 02. JD Simo & Luther Dickinson - Right Down There (4:02) (Do The Rump!, Forty Below Records, 2024) 03. Chadd Rupp & The Sugar Roots - You'll Be Singing My Songs (5:07) (Gate C 23, Lightning In A Bottle Records, 2024) 04. Georgia Thunderbolts - Wait (3:34) (Rise Above It All, Mascot Records, 2024) 05. Grady Champion - So What If My Best Ain't Good Enough (3:24) (Single, ANB Music Group, 2024) 06. Dirt Road Band - Been So Long (5:12) (Righteous, self-release, 2024) 07. Danielia Cotton - Make U Move (3:52) (Rare Child, Adrenaline/Cottontown...
2024-10-13
1h 34
Last Week in Medicine
Anticoagulation in AF with Cirrhosis, Trends in Anticoagulation for Acute PE, Beta Blockers for Acute MI with Normal EF, Finerenone for HFpEF, Continuous vs Intermittent Infusion for Antibiotics, Cefepime vs Piperacillin-Tazobactam for Sepsis
It's been a long time, but we are back!Apologies on the audio quality from Dr. Jenkins. Apparently he was recording from inside a cardboard box.Today we talk about important, practice changing studies in internal medicine from the last several months. What's the best anticoagulant in patients with cirrhosis and atrial fibrillation? Why do doctors use so much unfractionated heparin for acute PE? Should we still be using beta blockers in patients with acute MI? Does finerenone improve outcomes in HFpEF? Is continuous infusion of antibiotics better than intermittent? And will the cefepime vs...
2024-09-24
1h 05
apolut: Tagesdosis
Chinas unerschütterliche Haltung in der Taiwan-Frage | Von Rainer Rupp
Ein Kommentar von Rainer Rupp.Die jüngsten Militärmanöver Chinas rund um Taiwan unterstreichen Pekings Entschlossenheit, jede Bewegung in Richtung Unabhängigkeit der Inselprovinz zu verhindern. Die wird jedoch von den USA sowohl politisch als auch mit Waffenlieferungen unterstützt. Diese Entwicklungen verdeutlichen das Potenzial für eine Eskalation und einen größeren Konflikt in der ganzen Region.Im Gegensatz zu der oft widersprüchlichen, hysterischen und nicht selten irrational und moralin-betonten Sprache der westlichen Falken zeichnet sich die Sprache der politischen und militärischen Eliten Chinas und Russlands durch kühle Rational...
2024-06-21
09 min
Cop Talk
EP 86: 06/19/24 - A Disheartening Experience In Minneapolis
Share your stories and interact with Tim Rupp by email to coptalk@therev.fm Gary Austin and his wife, Keri, were in Minneapolis a couple weeks ago on a business trip. They witnessed a horrible verbal attack on officers in downtown Minneapolis. Gary and Tim discuss the apparent disrespect people have for any authority. Where, and why, did this start to happen? School teachers are belittled and ridiculed now for the way they run their classroom, and younger kids are being disrespectful.
2024-06-19
25 min
Volquest.com
Volquest Podcast: NCAA v. Tennessee, Virginia suit, recruiting weekend and hoops win over Kentucky
Join the crew of Austin Price, Rob Lewis, Grant Ramey and Eric Cain as the guys breakdown the latest developments in the NCAA vs. Tennessee saga, recruiting weekend and the basketball win over Kentucky at Rupp Arena. The podcast is presented by our friends over at Exterior Home Solutions.
2024-02-06
35 min
The College Experience: Basketball
College Basketball Picks - Wednesday, January 17th | The College Basketball Experience (Ep. 493)
The College Basketball Experience (@TCEonSGPN) of the Sports Gambling Podcast Network give out their College Basketball Picks for January 17th. On the show Colby Dant (@TheColbyD) and Ryan McIntyre (@Moneyline_Mac) give out their College Basketball best bets and break down every game on the slate.How will Danny Hurley and the UConn Huskies respond to their first game as the #1 team ranked in the country with the Creighton Bluejays coming to town? Can John Calipari and the Kentucky Wildcats bounce back against Chris Jans and the Mississippi State Bulldogs at Rupp? Is this...
2024-01-17
1h 32
The Good News with Angie Austin
Ep. 1339 - The Good News with Angie Austin - Chef Rich Rupp / Monica Mohindra / Anna De Souza
2023-11-14
00 min
Bandana Blues, founded by Beardo, hosted by Spinner
Bandana Blues #1021 - Right Mood For Blues
Show #1021 Right Mood For Blues 01. Name Droppers - Back To Chicago (3:06) (Blue Diamonds, Horizon Music Group, 2023) 02. Alex Lopez - Spanish Blues (5:08) (Looking For A Change, Maremil Music, 2023) 03. The Dig 3 - Red-Tailed Hawks (3:48) (Damn The Rent, self-release, 2023) 04. A.L. James Project - Can't Take It With You When You Go (3:40) (Single, self-release, 2023) 05. GA-20 - I Let Someone In (3:06) (Live In Loveland, Colemine/Karma Chief Records, 2023) 06. Leslie Vincent - Psychedelics With You (3:50) (About Last Night, self-release, 2023) 07. Chickenforce - Love You Like A Man (3:36) (2, Coast To Coast, 2023) 08. Chad Rupp...
2023-10-21
1h 38
Last Week in Medicine
Metformin and Long COVID, Central Lines and Thrombocytopenia, DOACs vs LMWH in Cancer Associated Thrombosis, Early vs Late Anticoagulation after Stroke with Atrial Fibrillation
Today we are joined by Dr. Brian Locke, recently graduated pulmonary-critical care fellow, who takes us on a journey of avoiding statistical fallacies. Does metformin reduce the likelihood of long COVID? Should we give platelet transfusions to thrombocytopenic patients before central line placement? Did the CANVAS trial change practice in cancer associated thrombosis? Should patients with a stroke due to atrial fibrillation start oral anticoagulation earlier or later? We discuss all these questions on more on today's episode. Check it out! Metformin for Long COVIDDefinition of Post Acute Sequelae of Sars-CoV-2 InfectionPlatelet Transfusion...
2023-06-28
59 min
Last Week in Medicine
Osmotic Demyelination Syndrome and Hyponatremia with Dr. Joel Topf, Apixaban vs Warfarin for On-X Aortic Valve, Perioperative Blood Pressure Strategies, Diagnostic Accuracy of CT Abdomen Without Contrast
Today we have a special guest, Dr. Joel Topf, board-certified nephrologist and medical educator extraordinaire. Our listeners will likely recognize Dr. Topf from his prolific tweeting @Kidney_boy, as well as his numerous appearances on the Curbsiders podcast. He is a co-founder of the NephJC on Twitter, and host and founder of the NephJC podcast Freely Filtered. He is also host of the podcast Channel Your Enthusiasm, a deep dive monthly recap of the nephrology textbook Clinical Physiology of Acid Base and Electrolyte Disorders by Dr. Burton Rose (who, incidentally, is the creator of the original UpToDate). Dr. Topf...
2023-05-25
1h 08
Last Week in Medicine
Doxycycline Post-Exposure Prophylaxis for STIs (DoxyPEP), High Dose Prophylactic Anticoagulation for COVID-19 (ANTICOVID), Rates of Fracture Non-union and Bisphosphonates
This week we have special guest, Dr. Adam Spivak, to talk about the new study on doxycycline post-exposure prophylaxis for STIs. Dr. Spivak is an infectious disease expert and works in both an HIV clinic and a free PrEP clinic. I also review the latest COVID-19 anticoagulation trial and a paper looking at rates of fracture non-union in people who receive bisphosphonates. Check it out! Doxycycline Post-exposure Prophylaxis for STIsHigh dose prophylactic anticoagulation in COVID-19Bisphosphonate and Rates of Fracture Non-unions Music from Uppbeat (free...
2023-04-27
46 min
Last Week in Medicine
Thiazides for Kidney Stones, Hydrocortisone for Severe Pneumonia (CAPE COD), 2023 GOLD COPD Guidelines, Real World Use of Oral Antibiotics for Infective Endocarditis
Today we have special guest, Dr. Sarah Gilligan, a nephrologist, to talk about the new study of thiazides for kidney stones. We all learn in medical school that thiazides reduce urinary excretion of calcium, but does that really translate to fewer kidney stones? We also have Dr. Brian Locke on to talk about the CAPE COD trial, a big new critical care paper on using hydrocortisone in severe pneumonia, as well as the latest COPD guidelines and a retrospective study of oral antibiotics for infective endocarditis. Check it out! Hydrochlorothiazide for Kidney Stones
2023-03-25
1h 19
Last Week in Medicine
Antibiotic Duration for Febrile UTI in Males, Lower GI Bleeding Guidelines, Intravenous Contrast in Patients with Acute Kidney Injury
Today we welcome special guest and fellow EBM lover Dr. Mita Hoppenfeld to talk about a new randomized controlled trial evaluating the best duration of antibiotics for febrile UTI in men. Is 7 days as good as 14 days? We also review the latest guidelines for lower GI bleeding and a new retrospective study on renal outcomes in patients with AKI who receive IV contrast. 7 vs 14 days of antibiotics for Febrile UTI in MenLower GI Bleeding GuidelinesIV Contrast in patients with AKI Music from Uppbeat (free for Creators!):
2023-02-25
45 min
Volquest.com
Volquest Podcast: How bad of a loss was Rupp? New football commit
On this week's episode of the Volquest Podcast, Austin {rice, rob Lewis and Eric Cain breakdown Tennessee's loss to Kentucky, a new football commit and the Vols showing in the desert to kickoff the baseball season.
2023-02-21
29 min
apolut: Tagesdosis
West-Sanktionen gegen Erdbebenopfer | Von Rainer Rupp
Verbrechen des Wertewestens gegen die MenschlichkeitEin Kommentar von Rainer Rupp.Die Heuchelei der angeblich so sehr um die Menschlichkeit und um westliche Werte besorgten Regierungs- und Medieneliten in den korrupten US/NATO/EU-Demokraturen schreit schon lange zum Himmel. Nach den jüngsten Erfahrungen im Ukraine-Krieg, wie diese West-Eliten ganze Generation der ukrainischen Jugend sinnlos als Kanonenfutter verheizen, dachten viele, dass eine Steigerung der Verkommenheit der US/NATO/EU-Regierungsvertreter kaum noch möglich war.Pentagon-Chef Lloyd Austin hatte nämlich anlässlich seines Besuches in Warschau am 25. April 2022 erklärt, dass...
2023-02-17
08 min
Last Week in Medicine
Early Vasopressors and Restrictive Fluids in Septic Shock (CLOVERS), Furosemide vs Torsemide in Heart Failure (TRANSFORM-HF), Aspirin vs Enoxaparin after Extremity Fracture (PREVENT CLOT), Haloperidol for ICU Delirium (AID-ICU)
We're back with Season 4! Sorry for the unplanned hiatus. Today we talk about the CLOVERS trial, which tested the hypothesis that early vasopressors and restrictive fluid would be superior to liberal fluids plus rescue vasopressors. We also looked at the TRANSFORM-HF study, which compared torsemide and furosemide in congestive heart failure, the PREVENT CLOT study, which compared aspirin to enoxaparin for VTE prophylaxis after a traumatic fracture, and the AID-ICU study, which compared haloperidol to placebo in the treatment of ICU delirium. CLOVERS trialTorsemide vs Furosemide in CHFAspirin vs Enoxaparin for...
2023-01-31
51 min
Redd Talk
Burrow or Mahomes, 49ers or Eagles, SEC-Big 12 Challenge & Locks of the Week with Austin Bickett
& then there were 4…. Austin Bickett & I breakdown the 2 conference championships on Sunday. Super Bowl odds, X factors, anytime touchdown scorers & much more. Austin explains what’s likable and not so likable about the Cincinnati Bengals. We finish the show discussing the monster matchup at Rupp Saturday night, Kentucky-Kansas. Thanks for listening! Support our sponsors! Race to Cure Sarcoma: https://p2p.onecause.com/louisville/lexie-browning BETMGM: https://apps.apple.com/us/app/betmgm-sportsbook/id1430875409 UNDER DOG FANTASY: https...
2023-01-27
48 min
Story Loans
Using an SBA 7a Loan to Buy a Fast-Growing Business feat. Reid Rupp
Reid Rupp set out to acquire a business in early 2022 and ended up sealing the deal on a construction business in Austin, Texas in July thanks to the help of the SBA 7a loan program. In this episode, Reid recounts his story, which is one of opportunity, challenges, and in the end: resilience.
2022-11-15
28 min
LetsRun.com's Track Talk: The Home of Running and Track and Field
New York City Marathon Week is Here, Galen Rupp's Chances, Obiri's Debut, King Ches Voicemail, Austin for the Olympic Trials?
2022 TCS New York City Marathon race week is here and we start previewing the New York City Marathon even though our big blowout show will be the Supporters Club podcast on Friday. How will Galen Rupp do? What about Hellen Obiri in her debut? Should we care that incoming NYRR Board Chair Nnenna Lynch had a positive drug test, what about the NYRR giving prize money to non-binary athletes. Where should the Olympic Trials be? What about USATF Indoors? Plus a great voicemail about King Ches and the women's superstar you've never heard...
2022-11-01
1h 20
Passing The Mic: The VC Exchange
Passing the Mic: The VC Exchange - Sara Brand and Kerry Rupp
Sara Brand and Kerry Rupp are the General Partners of True Wealth Ventures, one of the first venture firms founded by women to invest in women. The Austin-based duo are known for being on the forefront of women-focused and women-led investments. As thought leaders in their fields, they are frequently sought out as speakers, coaches and judges as well as contributors on topics such as the advantages of investing in women entrepreneurs and the importance of engaging more women as investors. Each of the women have a set of skills and background experiences that not only guide them in t...
2022-09-13
38 min
Last Week in Medicine
SGLT2 Inhibitors for Acute Heart Failure, SGLT2 Inhibitors vs Metformin, High Dose Dexamethasone for COVID-19 in ICU, Isolated Distal DVT, Monkeypox, Blood Donor Sex and Mortality, Outcomes in Surgeons Who Operate the Night Before
Today we have a couple special guests under the age of 2. Birdie and Gus! Do SGLT2 inhibitors improve diuresis in acute heart failure? Are they better than metformin for reducing cardiovascular mortality? Is high dose dexamethasone better than standard dose in ICU patients with COVID? We also talk about outcomes in patients with isolated distal DVT compared to proximal DVT, a large case series of patients with monkeypox infection, blood donor outcomes and the outcomes for surgeons who operated the night before. Check it out! SGLT2-Inhibitors for Acute Heart Failure...
2022-07-22
44 min
Last Week in Medicine
Restrictive Fluids in Septic Shock, Short vs Standard Antibiotics in Neutropenic Fever, IV Vitamin C for Septic Shock, Hospitalist Workload and Patient LOS, Fluid Bolus for Intubation, General Internist Practice Choices
Today we are joined by Dr. Brian Locke to talk about multiple new critical care trials, including the CLASSIC trial of a restrictive vs standard fluid strategy, the LOVIT trial of vitamin C in septic shock, and the PREPARE-II trial of fluid bolus at the time of intubation to prevent cardiovascular collapse. We also look at whether 72 hours of antibiotics are safe in patients with neutropenic fever, whether hospitalist workload affects patient length of stay, and what kind of careers general internists are pursuing over the last decade. Restrictive Fluids for Septic ShockShort vs Standard...
2022-06-24
54 min
Last Week in Medicine
Inpatient Management of Opioid Use Disorder, Hep C Treatment in IVDU, Final SOLIDARITY Results for Remdesivir, TAVI for Moderate Risk Severe AS, Mediterranean Diet vs Low Fat Diet, Steroids for IgA Nephropathy, GLP-1s and Gallbladder Disease
Today we had Dr. Patricia Liu to talk about a new study from Journal of Hospital Medicine on the management of opioid use disorder in the hospital. And then we got a little carried away covering way too many articles! Inpatient Management of Opioid Use DisorderHepatitis C Care for People Who Inject DrugsFinal SOLIDARITY trial results for RemdesivirTAVI for Moderate Risk Severe Aortic StenosisMediterranean Diet vs Low Fat Diet for Secondary Prevention of CVDSteroids for IgA NephropathyGLP-1 Agonists and Gallbladder DiseasePig to Human K...
2022-05-25
58 min
Last Week in Medicine
2022 AHA/ACC/HFSA Heart Failure Guidelines with Dr. James Fang, Guideline Committee Member
Today, Dr. James Fang, Chief of Cardiovascular Medicine at the University of Utah, and AHA/ACC/HFSA Heart Failure Guideline Committee Member, joins us to talk about the new heart failure guidelines, published in April 2022. We talk about the new classifications, including HF with improved EF and HF with mildly reduced EF, and new recommendations for medical therapy for all the heart failure types. How do you start someone on GDMT? Who should get SGLT-2 inhibitors? How can we get more people on ARNIs? Dr. Fang provides lots of clinical pearls and practical wisdom for applying these new recommendations. C...
2022-05-04
32 min
Last Week in Medicine
Oral Carbapenem for Complicated UTIs, Awake Proning for COVID-19, 1-2 Months DAPT vs 12 Months DAPT, Low Sodium Diet for Heart Failure, Excess Mortality From COVID-19, IV Iron and Anaphylaxis, Pickle Juice for Cramps in Cirrhosis
Dr. Brian Locke is back to talk about that "nonrandomized" proning trial. We also talk about the new oral carbapenem for UTI trial, whether 1-2 months of DAPT is non-inferior to 12 months of DAPT, whether less than 1500 mg of sodium reduces heart failure hospitalizations, the risk of anaphylaxis from IV iron, and whether pickle juice is effective for treating cramps in cirrhosis. Check it out! Oral Tebipenem vs IV Ertapenem for Complicated UTIAwake Proning for Hospitalized COVID-19 Patients1-2 Months of DAPT vs 12 months of DAPT vs ACSLow Sodium Diet for Heart F...
2022-04-23
50 min
Last Week in Medicine
Reliever-Triggered ICS Therapy for Asthma, Methenamine for UTI Prevention, CT vs Invasive Coronary Angiography, Melatonin for Delirium Prevention, Interpretation of Home COVID Tests, Characteristics of Type 2 MI
Today we have Dr. Brian Locke back on to talk about asthma management and a new trial of reliever-triggered inhaled glucocorticoids for Black and Latinx patients with asthma. Other questions we try to answer: Does methenamine prevent recurrent UTIs in women? Should CT coronary scan be done before invasive coronary angiography? Does melatonin prevent delirium in ICU patients? How good are patients at interpreting home COVID tests? What is the most common cause of type 2 NSTEMI? Give it a listen and find out! Reliever Triggered Inhaled Glucocorticoid Therapy in Black and Latinx Asthma PatientsMethenamine vs A...
2022-03-22
1h 05
Last Week in Medicine
Paxlovid for COVID-19, Ivermectin Ineffective for COVID-19, One Year Outcomes for ICU COVID-19 Patients, Diagnostic Strategies for Ruling Out PE, Thiamine for Alcohol Use Disorder, Skin Color and Pulse Oximetry
We finally have the published trial results for Paxlovid! We also look at the latest trial showing the ivermectin is ineffective in treating COVID-19 and one year outcomes in ICU COVID-19 patients. We also look at a meta-analysis of trials looking at different diagnostic strategies for ruling out PE, a retrospective study of thiamine use in ICU patients with alcohol use disorder, and a new study on pulse oximetry in people with different skin color. Check it out! Paxlovid for High Risk, Nonhospitalized Patients with COVID-19Ivermectin for Mild to Moderate COVID-19 County-Level P...
2022-02-25
42 min
Freedom Entrepreneur Podcast
My Homeschool Journey: How I transitioned from my 9 to 5 while building a business and homeschooling my kids
Is homeschooling your kiddos on your mind, but as a working mama you can't even imagine HOW you could ever accomplish the task of homeschooling while working - let alone building a business. Friends, it IS possible and today I share my journey from working full time while building a business and homeschooling three of my kids to then running my business while homeschooling. Our story covers online school vs at home curriculum as well as unit study programs. Plus, I discuss how I divide my time to achieve balance. Mama, you can...
2022-02-08
25 min
Passive Income Examiner
My Homeschool Journey: How I transitioned from my 9 to 5 while building a business and homeschooling my kids
Is homeschooling your kiddos on your mind, but as a working mama you can't even imagine HOW you could ever accomplish the task of homeschooling while working - let alone building a business. Friends, it IS possible and today I share my journey from working full time while building a business and homeschooling three of my kids to then running my business while homeschooling. Our story covers online school vs at home curriculum as well as unit study programs. Plus, I discuss how I divide my time to achieve balance. Mama, you can...
2022-02-08
25 min
Passive Income Examiner- Work From Home, Freelancers, Affiliate Marketers, Passive Revenue, Blogging, Passive Income Strategies
My Homeschool Journey: How I transitioned from my 9 to 5 while building a business and homeschooling my kids
Is homeschooling your kiddos on your mind, but as a working mama you can't even imagine HOW you could ever accomplish the task of homeschooling while working - let alone building a business. Friends, it IS possible and today I share my journey from working full time while building a business and homeschooling three of my kids to then running my business while homeschooling. Our story covers online school vs at home curriculum as well as unit study programs. Plus, I discuss how I divide my time to achieve balance. Mama, you can...
2022-02-07
26 min
Last Week in Medicine
Balanced Crystalloid vs Normal Saline (PLUS trial), Midline vs PICC, LOLA for Hepatic Encephalopathy, Eat-Walk-Engage Program for Older Inpatients, Post-Discharge Thromboprophylaxis for COVID-19, Mindfulness Training and Burnout
Today we are joined by Dr. Brian Locke to talk about the newest big trial on IV fluids in critically ill patients and a meta-analysis that looks at all the similar trials. Is this question finally settled?We also look at PICC lines vs midlines, IV L-ornithine L-aspartate in acute treatment of hepatic encephalopathy, a new ward-based program for delirium prevention in older inpatients, post-discharge thromboprophylaxis for high risk COVID patients, and whether mindfulness training can help burnout in residents.Balanced Multielectrolyte Solution vs Normal Saline in Critically Ill Patients (PLUS)Balanced Crystalloid vs...
2022-01-28
49 min
Last Week in Medicine
Ultrasound JVP to Estimate CVP, IV Metoprolol vs Diltiazem for Atrial Fibrillation with RVR, Ischemic Stroke and Bleeding Risk with Apixaban vs Rivaroxaban, Reducing Sleep Interruptions in Hospital, Outpatient Remdesivir, Molnupiravir for COVID-19
It's our last episode in 2021! This episode we have Dr. Libo Wang and Dr. Jon Harrison on to talk about their new paper in the Annals of Internal Medicine about ultrasound JVP for estimating CVP, validated with right heart catheterization. We also ask them their thoughts on a new meta-analysis looking at metoprolol vs diltiazem for atrial fibrillation with RVR. We also look at a new large retrospective study of apixaban vs rivaroxaban for stroke prevention, a study looking at reducing sleep interruptions in the hospital, and two new outpatient therapies for COVID-19 infection. Happy...
2021-12-31
1h 11
Last Week in Medicine
Chlorthalidone in CKD, Factor XI Inhibition for VTE Prevention, Untreated Subsegmental PE and Risk of Recurrent VTE, Rivaroxaban and GI Bleeding, Mental Stress Induced Ischemia, Depression and Residency, Patient Outcomes for Part Time Hospitalists
Somehow we got through 7 articles today, and none of them are about COVID-19! Happy Thanksgiving! Chlorthalidone in CKDMilvexian for VTE PreventionRisk of Recurrent VTE in Subsegmental PERivaroxaban associated with higher rates of GI bleedingDepression and ResidencyMental-Stress Induced Myocardial IschemiaPatient Outcomes for Part Time HospitalistsMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2RMusic...
2021-11-25
59 min
Last Week in Medicine
Race and Estimated GFR, Bleeding Risk in Oral Anticoagulation after First VTE, HEP-COVID trial, High Dose Dexamethasone for COVID-19
Today we talk about the effect of eliminating the race coefficient from the estimated GFR calculators, the risk of bleeding from anticoagulation after first unprovoked VTE, another trial looking at therapeutic anticoagulation in COVID-19, and whether 12 mg of dexamethasone is better than 6 mg for severe COVID-19 infections. New GFR Equations without RaceRace, Genetic Ancestry and Estimating Kidney FunctionLong Term Bleeding Risk from Oral AC after First Unprovoked VTETherapeutic Heparin for COVID-19 (HEP-COVID)High Dose Dexamethasone for Severe COVID-19Music from...
2021-10-28
50 min
Last Week in Medicine
Empagliflozin for HFpEF, Antibiotic Duration for UTIs in Men, Targeted Temperature after Cardiac Arrest, Normal Saline vs Balanced Solution in ICU Patients, Baricitinib and Therapeutic Anticoagulation for Hospitalized COVID-19 Patients
We're back after a nice relaxing summer taking care of a surge of COVID-19 patients. To start off season 3 we decided to do a rapid review of some of the best articles over the last three months. Dr. Brian Locke returns to help us break down some critical care papers, we talk about the miracle of SGLT-2 inhibitors, the treatment of UTIs in men, and the latest in COVID-19 literature. Hypothermia vs Normothermia after Cardiac ArrestEmpagliflozin for Heart Failure with Preserved EFAntibiotic Duration for Afebrile UTIs in MenNormal Sal...
2021-10-01
1h 01
Across The Cavs
Across The Cavs S6 E10 - CROSSOVER with Chicken and the Nuggets
Jacob Rupp and Noah Reynolds of the Chicken and the Nuggets Podcast join to talk Denver hoops, living, and so much more. Shoutout to Austin Rivers.
2021-06-04
33 min
Last Week in Medicine
Antibiotic Duration for Prosthetic Joint Infections, Colorectal Cancer Screening Guidelines, Hospital Observation after ACS Ruled Out in ED, Morning Discharges, Personalized Steroid Regimen for COPD Exacerbation
Today is our season 2 finale, and we have a master class on prosthetic joint infections from Dr. Laura Certain. Is 6 weeks as good as 12 weeks for prevent recurrent infections? How does the surgeon decide what kind of surgery to do? Should we use oral or IV antibiotics? When should you use rifampin?? Dr. Certain answers all these questions and more. We also talk about the new colon cancer screening guidelines from USPSTF, hospital admission for chest pain after ACS ruled out in the ED, whether morning discharges improve patient throughput, and a study looking at personalized steroid dose...
2021-06-03
1h 03
Last Week in Medicine
Antibiotic Delay Intervals and Hospital Mortality for Patients with Suspected Sepsis, Guidelines for High Flow Nasal Oxygen and Point of Care Ultrasound for Acute Dyspnea, Screening for Atrial Fibrillation in Older Patients
How long can you delay antibiotics in patients with suspected sepsis before the risk of hospital mortality increases? What proportion of patients with suspected sepsis end up having actual sepsis? Dr. Devin Horton joins us to review a paper in Critical Care Medicine that tries to answer these questions. Antibiotic Delay Intervals and Hospital Mortality for Patients with Suspected SepsisHigh Flow Nasal OxygenPOCUS for Acute DyspneaScreening of Atrial Fibrillation in Older PatientsMusic from https://filmmusic.io"Sneaky Snitch" by Kevin Mac...
2021-05-13
45 min
Last Week in Medicine
Hospital at Home for Geriatric Patients, RAAS Inhibition and Pulmonary Hypertension, Vaccine Induced Immune Thrombotic Thrombocytopenia (VITT)
Today we have special guest Dr. Natalie Como to talk about Hospital at Home and what it's like to practice hospital medicine at a rural critical access hospital. We also look at a retrospective paper on ACE/ARBs in veterans with pulmonary hypertension and talk about vaccine-induced immune thrombotic thrombocytopenia (VITT). Check it out! Hospital at Home with Comprehensive Geriatric Assessment RAAS Inhibition and Pulmonary HypertensionVaccine-Induced Immune Thrombotic Thrombocytopenia Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)
2021-04-28
59 min
Last Week in Medicine
Three Days of Antibiotics for Pneumonia, IV Contrast and Kidney Function, DOACs for Valvular Atrial Fibrillation
Today we are joined by heavy hitter Dr. Brian Locke to talk about the new paper on 3 vs 8 days of antibiotics for pneumonia, a clever new paper looking at whether there is any association between IV contrast and kidney function, and a new retrospective study on DOAC use for valvular atrial fibrillation. Check it out! Three Days of Antibiotics for PneumoniaIV Contrast and Kidney FunctionDOACs for Valvular Atrial FibrillationMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC B...
2021-04-08
51 min
Last Week in Medicine
Weekly Semaglutide for Weight Loss (STEP 1, 2 and 3 Trials), 4PEPS Rule for Pulmonary Embolism, Nafcillin vs Cefazolin for Epidural Abscess, Ferritin/Procalcitonin Ratio for COVID19, Intermediate Thromboprophylaxis for COVID19
Today we are doing double duty: podcasting and parenting. Fortunately our babies were well-behaved. We talk about three trials for semaglutide and weight loss and a new 4 level pre-test probability rule for diagnosing PE. We also talk about a retrospective study of cefazolin vs nafcillin for epidural abscess, a ferritin/procalcitonin ratio for differentiating bacterial from COVID pneumonia, and a new randomized controlled trial of intermediate thromboprophylaxis for ICU patients with COVID19. Check it out! Semaglutide for Weight Loss (STEP 1)Semaglutide for Weight Loss in Diabetics (STEP 2)Semaglutide + Intensive Calorie Restriction for Weight Loss (STEP...
2021-03-24
50 min
Last Week in Medicine
Albumin Infusion for Decompensated Cirrhosis (ATTIRE trial), Terlipressin for Type 1 Hepatorenal Syndrome (CONFIRM trial)
Today has a nice liver disease theme. Does targeting a serum albumin above 3 g/dL reduce death, infections and kidney failure in patients with decompensated cirrhosis? Does terlipressin work in hepatorenal syndrome? Albumin Infusion for Decompensated CirrhosisTerlipressin for Type 1 Hepatorenal Syndrome Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGK...
2021-03-11
39 min
Last Week in Medicine
IL-6 Receptor Antagonists Reduce Mortality in Critically Ill COVID-19 Patients (REMAP-CAP, RECOVERY), Convalescent Plasma Fails to Improve Mortality
Today I am joined by Infectious Disease expert Dr. Emily Spivak to talk about the latest batch of tocilizumab trials for COVID-19 and a meta-analysis of all the convalescent plasma trials. Check it out! Tocilizumab in Hospitalized Patients with COVID-19 (COVACTA)IL-6 Receptor Antagonists in Critically Ill Patients with COVID-19 (REMAP-CAP)RECOVERY Tocilizumab pre-printMeta-analysis of Convalescent Plasma for COVID-19Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/b...
2021-03-04
42 min
Last Week in Medicine
Gender-Based Discrimination and Harassment Among Hospitalists, Educational Resource Utilization in Internal Medicine Residents, Transfusion Thresholds for ACS, DOACs for VTE prevention in CKD
Today we have special guests Dr. Emily Signor and Dr. Amanda Breviu, two hospitalists, to talk about a survey published in JHM on gender-based discrimination among hospitalists. We also discuss a survey published in JGIM on educational resources used by internal medicine residents. Check it out! Gender Based Discrimination and Harassment Among HospitalistsEducational Resource Utilization Among Internal Medicine ResidentsLiberal vs Restrictive Transfusion Threshold for Patients with ACS and AnemiaDOACs for VTE prevention in CKDMusic from https://filmmusic.io"Sneaky Snitch" by...
2021-02-18
1h 05
Last Week in Medicine
Early Ablation vs Medications for Atrial Fibrillation (STOP-AF First, EARLY-AF), ACEi and ARBs in COVID-19, IV vs Oral Antibiotics for Appendicitis, Rifaximin after TIPS, Low vs High Oxygen Targets
Today we have a special guest, Dr. Jared Bunch, an international expert in atrial fibrillation and ablation, to talk about the state of atrial fibrillation and which patients benefit from early catheter ablation based on two new trials published last week in the NEJM. We also talk about whether you should stop ACEi or ARBs in patients admitted with COVID-19, whether oral antibiotics are adequate for uncomplicated appendicitis, and whether you should target a high (90 mmHg) or low (60 mmHg) paO2 in patients with respiratory failure. STOP-AF First trialEARLY-AF trialACEi and ARBs in COVID-19
2021-02-04
57 min
The John Clay Podcast
Kentucky-Texas college basketball preview
Ranked No. 5 in the latest AP College Basketball Top 25, the Texas Longhorns visit Rupp Arena to take on the struggling Kentucky Wildcats as part of the SEC/Big 12 Challenge on Saturday, Jan. 30, 2021. UK is 5-10 on the season after losing at Alabama on Tuesday. Texas is 11-3, but the Longhorns are dealing with COVID-19 issues. Lexington Herald-Leader sports columnist John Clay talked with Texas beat writer Brian Davis of the Austin American-Statesman about Shaka Smart's team. John then talked to Kent Spencer, sports anchor at WHAS-11 in Louisville, about whether John Calipari's Wildcats can get their season turned around.
2021-01-29
33 min
Last Week in Medicine
Inhaled Treprostinil for Pulmonary Hypertension due to Interstitial Lung Disease, Omecamtiv Mecarbil for Systolic Heart Failure (HFrEF)
Today I am joined by pulmonary hypertension and heart failure expert, Dr. John Ryan, to talk about inhaled treprostinil for pulmonary hypertension due to ILD, and a new cardiac myosin activator, omecamtiv mecarbil, for treatment of systolic heart failure. Check it out! Treprostinil for Pulmonary Hypertension due to ILDOmecamtiv Mecarbil for Systolic Heart FailureMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from U...
2021-01-21
35 min
Last Week in Medicine
Prevalence of Pulmonary Embolism in Acute COPD Exacerbation, Tocilizumab for COVID-19 Round 3
WARNING: This episode is long on banter. If you would like to skip the intro conversation and get right to the articles, skip ahead to 12:13. Today we are joined by Dr. Jason Carr, pulmonary-critical care all-star, to talk about how often PE is present in patients with acute COPD exacerbations. We also review more tocilizumab RCTs because they just keep coming. Prevalence of Pulmonary Embolism in Acute COPD ExacerbationSTOP-IT COVID trialRCT-TCZ-COVID-19 trialCORIMUNO-TOCI-1 trialREMAP-CAP trial pre-printMusic from htt...
2021-01-14
54 min
Last Week in Medicine
Treatment of Inpatient Hypertension, Testing and Treatment of Primary Aldosteronism in Patients with Resistant Hypertension, Tocilizumab for COVID-19 Round 2
The president's supporters may have stormed the capitol and attempted a coup today, but the show must go on. Today I'm joined by Dr. Dani Babbel to talk about treatment of hypertension in the hospital, as well as testing for primary aldosteronism in patients with resistant hypertension. Check it out! Treatment and Outcomes in Inpatient Hypertension Testing for Primary Aldosteronism and MRA Use Among US VeteransTocilizumab in Hospitalized Patients with COVID-19Music from https://filmmusic.io"Sneaky Sni...
2021-01-07
35 min
Last Week in Medicine
Thrombosis and COVID-19
Today I do a quick review of the COVID-19 thrombosis literature from the last year to try to answer some of the following questions: Why does COVID-19 cause thrombosis? How many patients with COVID-19 develop thrombotic complications? Why do patients with COVID-19 on VTE prophylaxis still develop blood clots? Should we use intermediate dosing of anticoagulation for prophylaxis? What about full dose therapeutic anticoagulation (no!) What do the guidelines say? Lots of papers:JAMA IM Review Autopsy Findings and VTE in Patients with COVID-19Klok et al Helms et alShah et al
2020-12-30
17 min
Last Week in Medicine
Inappropriate Testing and Treating of Asymptomatic Bacteriuria, Baricitinib Plus Remdesivir for COVID-19 (ACTT-2), COVID-19 Vaccine, Noninvasive Respiratory Protocol for COVID-19, Iron Supplementation in Acute Heart Failure
Today we have special guest Dr. Valerie Vaughn to talk about her new paper in Open Forum Infectious Diseases about inappropriate treatment and testing for asymptomatic bacteriuria. Then we talk about the new ACTT-2 trial results of baricitinib plus remdesivir for COVID-19. We also review the BioNTech/Pfizer vaccine safety and efficacy results, a noninvasive respiratory protocol to reduce intubations in COVID-19, and iron deficiency in acute heart failure. Testing and Treating Asymptomatic Bacteriuria Initiated in the EDBaricitinib Plus Remdesivir for COVID-19 (ACTT-2 trial)Safety and Efficacy of the BNT162b2 mRNA Covid-19 Va...
2020-12-16
47 min
Last Week in Medicine
Patient Outcomes in Resident, APC and Solo Hospitalist Teams, Rapid Conversion to Oral Antibiotics in Pneumonia, SOLIDARITY trial for COVID-19
Today we have special guests Dr. Claire Ciarkowski and Dr. Stacy Johnson to talk about two recent papers they published, as well as the new SOLIDARITY trial results. Are patient outcomes the same for resident, APC and solo hospitalist teams? How do you get doctors to switch to oral antibiotics faster when treating pneumonia? And with the new SOLIDARITY results showing no benefits for remdesivir, should we still be using it for COVID-19? Resident, APC and Solo Hospitalist Team OutcomesRapid Conversion to Oral Antibiotics for PneumoniaSOLIDARITY trial for COVID-19
2020-12-10
52 min
Last Week in Medicine
Danish Mask Study, Rivaroxaban for Atrial Fibrillation and Bioprosthetic Mitral Valve, Convalescent Plasma Fails, Semaglutide in NASH, Once Weekly Insulin, Statin Nocebo Effect
We're back with our second episode of the new season. Dr. Rupp is sporting a new mustache, and we discuss the mysterious monolith discovered in the Utah desert. If you want to skip the banter, go to 6:56. This week we try to figure out what that Danish Mask Study really showed. Is it safe to use rivaroxaban in patients with a bioprosthetic mitral valve and A fib? Does convalescent plasma improve outcomes in COVID-19? Danish Mask StudyCDC Report on Kansas Mask MandatesRivaroxaban for A fib and Bioprosthetic Mitral ValveConvalescent Plasma...
2020-12-03
38 min
Last Week in Medicine
Remdesivir Redux, Tocilizumab Fails, Bamlanivimab gets EUA and mRNA Vaccines for COVID-19
We're back after a prolonged hiatus, ready to break down the latest and greatest in the medical literature. Today's episode will get you caught up on the newest treatments for COVID-19. We promise to talk about something else next time :) If you want to skip all the banter about Baby Yoda and politics, go to 8:36. Remdesivir for COVID-19 Final ReportTocilizumab for Hospitalized COVID-19 PatientsBamlanivimabPfizer VaccineModerna VaccineMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)Li...
2020-11-19
39 min
Last Week in Medicine
Caring for COVID-19 Patients in the Navajo Nation
Today we are joined by a special guest, Dr. Lawanda Jim, chief of internal medicine at Northern Navajo Medical Center, to talk about what it's been like taking care of patients during the pandemic in Shiprock, NM. Check it out! Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R
2020-07-16
34 min
Last Week in Medicine
Dexamethasone Reduces Mortality in COVID-19: The RECOVERY Trial
Today we're back with a spirited discussion of a pre-print publication for the dexamethasone arm of the RECOVERY trial. Should hospitalized COVID19 patients receive dexamethasone? Take a listen and decide for yourself. Dexamethasone in Hospitalized Patients with COVID-19Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R
2020-07-10
30 min
Last Week in Medicine
Remdesivir Shortens Time to Recovery in COVID19 (ACTT-1), CRP-Guided Antibiotics for Gram Negative Bacteremia, NT-pro-BNP in Syncope
We're back with another episode. We cover the latest highlights in COVID, including the exciting new results on remdesivir from the ACTT-1 trial. We also talk about whether you can use CRP to guide duration of antibiotic therapy in patients with gram negative bacteremia, and whether NT-pro-BNP can help you risk-stratify patients with syncope. Check it out! Remdesivir Shortens Time to Recovery in COVID19 (ACTT-1)CRP Guided Antibiotics or 7 Days vs 14 Days for Gram Negative Bacteremia NT-pro-BNP in SyncopeMusic from https://fil...
2020-06-05
36 min
Last Week in Medicine
Triple Antiviral Therapy for COVID-19, Remdesivir for Severe COVID-19, Convalescent Plasma, Hydroxychloroquine and Azithromycin in New York
We're back with some of the latest updates on COVID-19! Are hydroxychloroquine or azithromycin associated with increased risk of mortality or cardiac arrest? Does triple combination antiviral therapy shorten time to a negative viral swab? Does remdesivir shorten time to clinical improvement? Should we be giving patients convalescent plasma? If you were the patient with severe COVID-19, which therapies would you want?Hydroxychloroquine and Azithromycin in New York CityTriple Combination Therapy for COVID-19 in Hong KongRemdesivir in adults with Severe COVID-19Treatment of 5 Patients with Convalescent Plasma
2020-05-20
43 min
Last Week in Medicine
COVID-19 in New York City, Lopinavir-Ritonavir in Severe COVID-19, The French Hydroxychloroquine Study, Chinese Hydroxychloroquine RCT, VA Hydroxychloroquine Study, Compassionate Use of Remdesivir
It's been a while! We took a short hiatus while our lives were upended by the pandemic. But we couldn't stay away forever. Today we review some of the big trials published in the last month on Covid-19. We look at the large case series on New York patients published in JAMA, three hydroxychloroquine studies, the lopinavir-ritonavir study and the compassionate use of remdesivir study. Buckle up! 5700 Patients Hospitalized with COVID-19 in New York CityLopinavir-Ritonavir in Severe COVID-19Hydroxychloroquine in FranceHydroxychloroquine in China Hydroxychloroquine in Veterans C...
2020-04-30
40 min
Mark Masters
Mark Masters - Alan Bromwell
Alan Bromwell In this episode Mark Masters talks to Alan Bromwell, a 6 year comedian on the Comedy Works pro list based in Denver, CO. Mark drives Alan from Castle Rock to a ticketed show at Carter Payne in Colorado Springs, CO and they talk comedy, comedians, and stand up comics. They discuss: - driving to a show, guest spot driving - six years comedy - on the pro list, paid to perform at Comedy Works - worked 2.5 years unpaid - Almost Famous, 10 minute host spots Sundays and Wednesdays (sometimes Saturdays), 7 minute spots - Dana Gould, Joey Diaz (blacklisted), Pete Holmes ...
2020-03-23
1h 28
Last Week in Medicine
COVID-19 Update, Gabapentin for Alcohol Use Disorder, Apixaban versus Rivaroxaban for Atrial Fibrillation
Seems like a lot has happened in just one week! The whole world is different. Today we talk about some of the most recent articles published about the ongoing COVID-19 pandemic. We also discuss whether gabapentin can be used to treat people with alcohol use disorder, and whether apixaban is better than rivaroxaban for preventing strokes in people with atrial fibrillation. Incubation Period for COVID-19Risk Factors for Mortality in COVID-19Risk Factors for ARDS and Death in COVID-19Caring for Critically Ill Patients with COVID-19Detection of COVID-19 in ChildrenGa...
2020-03-18
29 min
Last Week in Medicine
Long Acting Injectable Therapy for HIV and Pregnenolone for Chronic Low Back Pain
Austin finally returns to the podcast with harrowing tales of almost being eaten by a wolf. Today we discuss a new NEJM paper about long acting injectable therapy for HIV and a new JAMA paper about pregnenolone, a neurosteroid that may help treat the scourge of primary care: chronic low back pain. Long Acting Cabotegravir and Rilpivirine for HIV-1Pregnenolone vs Placebo for Chronic Low Back Pain in Veterans Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)
2020-03-11
25 min
Last Week in Medicine
COVID-19, PPI Use and MDRO Colonization, Hospitalist Care of ED Boarders
Today we had Dr. Dani Babbel back on the show to talk about the latest COVID-19 updates, whether gastric acid suppression increases your risk of MDRO colonization, and how to improve care to patients boarding in the emergency department. Check it out! Characteristics of Covid-19 in ChinaCovid-19 Report from CDC of China Gastric Acid Suppression and MDRO Colonization Hospitalist Care of ED Boarders and Length of Stay Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://i...
2020-03-04
32 min
Mark Masters
Mark Masters - Jacob Rupp
Jacob Rupp In this episode Mark Masters talks to Jacob Rupp, a 6 year comedian who started in Boulder, CO, but lives in Denver now. Mark drives Jacob from Denver, CO to a show in Aspen, CO and they talk comedy, comedians, and stand up comics. [Note: This video starts mid conversation because of bad file management and ends mid conversation because the battery dies, apologies] They discuss: - Writing and deciding what is funny - Modifying material based on audience - Watch comic before to try to call back for an audience member - Hosting at Comedy Works - First...
2020-03-02
1h 21
Last Week in Medicine
Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia, High Consulting Hospitalists, Medicare for All
Today we had the pleasure of talking to Dr. Barbara Jones, first author on a new paper in JAMA IM about the outcomes in veterans treated with empirical anti-MRSA therapy vs standard therapy. She gives us a master class in propensity weighted analysis and instrumental variable analysis. We also look at whether outcomes are different in patients who are cared for by hospitalists who call more consults than their colleagues, and how much money we could save with a single payer system in the United States. Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia High Co...
2020-02-25
31 min
Last Week in Medicine
Plasma Exchange and Glucocorticoids for ANCA-Vasculitis and Dexamethasone for ARDS, aka the PLEX and DEX episode
Today we have the venerable EBM guru Dr. Brian Locke on the show to talk PLEX and DEX. Does plasma exchange for ANCA-vasculitis really work? Do steroids make any difference in patients with ARDS? Also, have you ever wondered which Hogwarts house your medical specialty belongs to? Plasma Exchange and Glucocorticoids for ANCA-Vasculitis Dexamethasone for Acute Respiratory Distress SyndromeThe Sorting Hat of Medicine: Why Hufflepuffs Wear Stethoscopes and Slytherins Carry ScalpelsMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC...
2020-02-19
31 min
Last Week in Medicine
Aspirin for VTE Prophylaxis after THA or TKA, Fluid Management for Sepsis in Patients with ESRD, Cirrhosis and CHF
Today we are joined by the man, the myth, and the legend, Dr. Stacy Johnson, to talk about a new meta-analysis of using aspirin for DVT prophylaxis after a total hip or knee replacement. We also review a new retrospective cohort study from Cleveland Clinic on whether it's safe to give the recommended 30 ml/kg fluid bolus to patients with sepsis who also have CHF, cirrhosis or ESRD. Check it out! Aspirin for VTE Prophylaxis after THA or TKA Fluid Management for Sepsis in Patients with ESRD, Cirrhosis and CHF
2020-02-11
29 min
Mark Masters
Mark Masters - Nate Brown
Nate Brown In this episode Mark Masters talks to Nate Brown, a 7 year comedian who hosted the Hodi's open mic for 2.5 years, which was the destination of many of the Mark Masters season 1 episodes. Mark drives Nate from Lonetree to an open mic at Loonee's in Colorado Springs, CO and they talk comedy, comedians, and stand up comics. [Note: This episode ends abruptly because the camera battery ran out] They discuss: - Nate an important part of Season 1 - Nate no longer hosts Hodi's open mic - Ft. Collins comedy scene - Hosting an open mic and comedy skills ...
2020-02-10
1h 27
Last Week in Medicine
CT Screening for Lung Cancer, Conservative vs Interventional Treatment for Spontaneous Pneumothorax
Today we are joined by the very smart Dr. Jason Carr, a pulmonary/critical care fellow, to talk about two big papers from the wonderful world of lungs. Does CT screening for lung cancer save lives? Do you have to put a chest tube in every patient with a spontaneous pneumothorax? Check it out! CT Screening for Lung Cancer, AKA NELSON Conservative vs Interventional Treatment for Spontaneous PneumothoraxMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org...
2020-02-04
28 min
Last Week in Medicine
Novel Coronavirus, High Sensitivity Troponins, Hydroxyethyl Starch for Abdominal Surgery and Testosterone Therapy in Men
It's our tenth episode! Thanks for getting us this far. Today we discuss the new coronavirus outbreak, what to do with high sensitivity troponins, whether hydroxyethyl starch should be used in abdominal surgery (spoiler alert: it shouldn't) and the appropriate use of testosterone therapy.Novel Coronavirus in China High Sensitivity Troponins and the Fourth Universal Definition of MIHydroxyethyl Starch versus Saline in Major Abdominal SurgeryEfficacy and Safety of Testosterone Treatment in Men Music from https://filmmusic.io"Sneaky Snitch" by Kevin Mac...
2020-01-28
27 min
Last Week in Medicine
Factor XIa Inhibition for VTE Prophylaxis, Physician Time Using EHR in Outpatient Encounters, Vitamin C and Thiamine for Septic Shock
Today we are joined by the wonderful Dr. Emily Signor to talk about new therapeutic approaches to DVT prophylaxis, how much time physicians spend using the EHR in clinic, and whether that Vitamin C cocktail works for septic shock. Check it out! Effect of Osocimab in Preventing VTE in Patients Undergoing TKA Physician Time Spent Using the EHR During Outpatient EncountersVitamin C, Thiamine and Hydrocortisone for Septic ShockMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC...
2020-01-22
30 min
Last Week in Medicine
Health Care Hotspotting, Valve Replacement in Asymptomatic Very Severe Aortic Stenosis, Free Medications and Treatment Adherence
Today we try something a little different -- three co-hosts! Dr. Dani Babbel joins Jenkins and Rupp for some lively discussion about hotspotting, very severe aortic stenosis and whether adherence improves when medications are free. Check it out! Health Care HotspottingEarly Surgery for Asymptomatic Aortic Stenosis Effect on Treatment Adherence of Distributing Essential Medicines at No ChargeMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)...
2020-01-14
32 min
Last Week in Medicine
Hospital Care at Home, Adverse Events in “Social" Admissions, NT-ProBNP Before Non-Cardiac Surgery, Alcohol Abstinence in Drinkers with Atrial Fibrillation
Happy New Year and welcome to the first episode of 2020! We've got some great articles to review today. Can we save money by taking care of some acutely ill patients in their own homes? Are patients admitted for "social" reasons at the same risk for adverse events as acutely ill patients? Can NT-ProBNP level predict cardiovascular death and myocardial injury after non-cardiac surgery? Does limiting alcohol intake reduce atrial fibrillation recurrence? Listen to find out! Hospital Level Care at Home for the Acutely Ill Adverse Events in Patients Hospitalized Without Definite Medical AcuityPreope...
2020-01-07
35 min
Last Week in Medicine
Gadolinium in CKD Stage 4 and 5, Metoprolol and COPD Exacerbations, Vitamin D in Critically Ill Patients, Politics and Mood in Young Physicians
Dr. Rupp is back! Today we talk about whether it's safe to give group 2 gadolinium based contrast agents to patients with CKD stage 4 and 5 and whether metoprolol can be used to prevent COPD exacerbations. We also shine some more sunlight on the sunshine vitamin's inability to change any meaningful outcomes, and discuss some interesting data from the Intern Health Study. Risk of Nephrogenic Systemic Fibrosis in Patients with Stage 4 or 5 CKD Receiving Group II Gadolinium Based Contrast AgentMetoprolol for the Prevent of Acute Exacerbations of COPDEarly High-Dose Vitamin D3 for Critically I...
2019-12-17
25 min
Last Week in Medicine
Upper GI Bleeding Guidelines, E-cigarette and Vaping Associated Lung Injury, Beta Blockers and HFpEF Exacerbations
This week we have a special guest host, Dr. Dani Babbel. We talk about the new guidelines on upper GI bleeding, a new study on E-VALI, and the possible association of beta blockers with heart failure hospitalizations in heart failure with EF > 50%. Management of Upper GI Bleeding GuidelinesClinical presentation, treatment and short term outcomes of E-VALIAssociation of Beta-Blocker Use with Heart Failure Hospitalizations in HFpEFMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/l...
2019-12-10
30 min
Last Week in Medicine
D-dimer Adjusted for Clinical Probability of PE, Work Schedules of Hospitalists, Inappropriate Fluoroquinolone Prescribing, Utilization and Outcomes of Lytics in Acute PE
Can you get away with a higher d-dimer value in patients with a low pre-test probability for PE? Does working more days in a row improve patient outcomes? How often are people inappropriately prescribing fluoroquinolones? How often are people using systemic lytics vs catheter directed lytics in acute PE, and what are the outcomes?Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License cod...
2019-12-02
24 min
Last Week in Medicine
Vitamin D in Diabetic Kidney Disease and SGLT-2 Inhibitors for Heart Failure Reduced Ejection Fraction
Today we talk about the effects of vitamin D in progression of CKD in people with diabetes, and whether SGLT-2 inhibitors like dapagliflozin can be used to treat heart failure with reduced ejection fraction in people without diabetes. We also talk about ticagrelor monotherapy after three months of DAPT, rivaroxaban for the treatment of APS (don't do it!) and LDL targets for stroke prevention. Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): ht...
2019-11-26
23 min
Last Week in Medicine
The Apple Heart Study, Colchicine after MI
Lots of cardiology to discuss this week with the Apple Heart and COLCOT studies, both published in the New England Journal of Medicine. We also talk about the 3 Wishes Project, the net clinical benefit of oral anticoagulation with aging over 75, the benefits of non-pharmaceutical treatment of agitation, and getting blood cultures before you give antibiotics. Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License co...
2019-11-19
23 min
Last Week in Medicine
Intensifying Blood Pressure Therapy in the Hospital, Asymptomatic Bacteriuria, DRIP score in Pneumonia
Should we add blood pressure medications or increase the dose while patients are in the hospital? What are the risk factors and outcomes for people who receive antibiotics for asymptomatic bacteriuria? And how does the DRIP score stack up against previous tools for identifying patients at high risk for drug resistant pneumonia? Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKG...
2019-11-12
29 min
Jews You Should Know
The Jewish Positive Thinker: A Conversation with Chaya Hinda Allen
ABOUT THIS EPISODE Chaya Hinda Allen grew up in Liverpool, England, married a Chassidic man from Austin, Texas, and moved with her young family to a fledgling community called Beitar, half an hour outside Jerusalem. In the decades since, she has pioneered a methodology to help (mainly women) find their connection with G-d and channel His love for their own emotional development. Jewish Positive Thinking - as she's dubbed her approach - has impacted thousands of women throughout the world, promoting an authentic Jewish perspective to emotional healing. Learn about her work at www.ChayaHinda...
2019-03-11
1h 07
Women in Tech Podcast, hosted by Espree Devora
Sara Brand of True Wealth Ventures, Investing in Gender Matters: Women in Tech Austin
Don't miss out on the next #womenintech podcast episode, get notified by signing up here http://womenintechshow.com Women in Tech: Sara Brand “Investing in Gender Matters” #womenintech Show is a WeAreTech.fm production. This episode is powered by SpyCloud - https://spycloud.com/ - Protect employees and customers from account takeover & Impact Hub Austin - https://www.impacthubaustin.com/ - Inspiring coworking, shared office spaces, programs and accelerators in the heart of Austin. To be featured on the podcast go to http://womenintechshow.com/feature Host, Espree Devo...
2018-11-07
35 min
Parks Pod
Bruce Parkinson Interview
**Bruce Parkinson Interview** This week I start by giving my thoughts on a few NBA Playoff opening round games followed by an intriguing interview with my father Purdue legend Bruce Parkinson. Interview Highlights: (:20) NBA Playoff Game 1 thoughts, (9:25) Jack Parkinson Shadow, (11:00) Alolph Rupp stories, (12:40) Winning the Muncie Sectional, (18:30) Recruiting process, (20:00) Tennessee visit wow factor, (25:00) Mr. Thornburg unwavering belief, (31:40) Expectations as a Purdue freshmen, (37: 50) John Wooden/Dick Enberg picture, (40:58) Single game assist record, (43:40) IU Rivalry & Quinn Buckner, (48:30) NIT Championship, (52:10) Pan Am Gold Medal & Robert Parish, (56:40) Being drafted into the NBA, (1:02:30) Changes in game today, (1:07:30) Watching old game footage with myself & Kenneth Lowe, (1:10...
2018-04-16
1h 20
Ideas to Invoices
Sara Brand and Kerry Rupp, general partners of True Wealth Ventures
Sara Brand and Kerry Rupp, are general partners of True Wealth Ventures, a $20 million venture capital fund based in Austin and focused on investing in women led companies in the sustainable consumer and consumer health industries.
2017-07-28
26 min