Shows
The Rounds TableEpisode 117 - Brensocatib for Bronchiectasis and Alteplase for Posterior Circulation Ischemic StrokeSend us a textWelcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast. This week, Dr. Mike Fralick and special guest Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration discuss two recent papers: the use of brensocatib (a DPP-1 inhibitor) to treat bronchiectasis, and the effect of alteplase administered 4.5 to 24 hours after stroke in patients with mild posterior circulation stroke who did not receive thrombectomy. Two papers, here we go!Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis (0:00 – 12:46)Alteplase for Posterior Circulation Ischemic St...2025-05-0826 minThe Rounds TableEpisode 115 - Tirzepatide for Obesity Treatment and Diabetes PreventionSend us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go!Tirzepatide for Obesity Treatment and Diabetes Prevention (0:00 – 10:24).The Good Stuff:We've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here! (10:25 - 11:23)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-04-2411 minThe Rounds TableEpisode 115 - Tirzepatide for Obesity Treatment and Diabetes PreventionSend us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go!Tirzepatide for Obesity Treatment and Diabetes Prevention (0:00 – 10:24).The Good Stuff:We've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here! (10:25 - 11:23)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-04-2411 minThe Rounds TableEpisode 113 - Vitamin D in Clinically Isolated Syndrome Typical of Multiple SclerosisSend us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go!High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).Announcements (7:36 – 9:15):Canadian physicians, 2025 CMPA Council elections are underway in Alberta and Ontario! View the candidates and cast your ballot here.Check out Dr. Yati...2025-04-1009 minThe Rounds TableEpisode 113 - Vitamin D in Clinically Isolated Syndrome Typical of Multiple SclerosisSend us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go!High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).Announcements (7:36 – 9:15):Canadian physicians, 2025 CMPA Council elections are underway in Alberta and Ontario! View the candidates and cast your ballot here.Check out Dr. Yati...2025-04-1009 minThe Rounds TableEpisode 110 - Restrictive versus Liberal Transfusion in Myocardial Infarction with Dr. Jeff CarsonSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Jeffrey Carson, Distinguished Professor of Medicine at the Rutgers Robert Wood Johnson Medical School and Provost at Rutgers University, to chat about his recent publication - Restrictive versus Liberal Transfusion in Myocardial Infarction — A Patient-Level Meta-Analysis. Here we go!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-03-1328 minThe Rounds TableEpisode 110 - Restrictive versus Liberal Transfusion in Myocardial Infarction with Dr. Jeff CarsonSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Jeffrey Carson, Distinguished Professor of Medicine at the Rutgers Robert Wood Johnson Medical School and Provost at Rutgers University, to chat about his recent publication - Restrictive versus Liberal Transfusion in Myocardial Infarction — A Patient-Level Meta-Analysis. Here we go!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-03-1328 minThe Rounds TableEpisode 108 - Endovascular Treatment in Stroke with Medium Vessel OcclusionSend us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he will discuss a paper exploring endovascular treatment (EVT) for acute ischemic stroke due to medium-vessel occlusion. Here we go!Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion (0:00 – 6:02).This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-02-2706 minThe Rounds TableEpisode 108 - Endovascular Treatment in Stroke with Medium Vessel OcclusionSend us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he will discuss a paper exploring endovascular treatment (EVT) for acute ischemic stroke due to medium-vessel occlusion. Here we go!Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion (0:00 – 6:02).This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-02-2706 minThe Rounds TableEpisode 106 - Screening for Diabetes and Dyslipidemia after Pregnancy Complicated by Hypertension or Diabetes with Dr. Amy YuSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat about her hot-off-the press publication - Population-Level Screening for Diabetes and Dyslipidemia After Pregnancies Complicated by Hypertension or Diabetes!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-02-1918 minThe Rounds TableEpisode 106 - Screening for Diabetes and Dyslipidemia after Pregnancy Complicated by Hypertension or Diabetes with Dr. Amy YuSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat about her hot-off-the press publication - Population-Level Screening for Diabetes and Dyslipidemia After Pregnancies Complicated by Hypertension or Diabetes!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-02-1918 minThe Rounds TableEpisode 105 - Intravenous Thrombolysis in Minor Ischemic Stroke with Intracranial OcclusionSend us a textWelcome back Rounds Table Listeners!We are back today with a solo episode with Dr. Mike Fralick!This week, he will discuss a paper exploring the role of intravenous thrombolytic therapy in patients with minor ischemic stroke and intracranial vessel occlusion. Here we go!Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open-label, phase 3 superiority trial (0:00 – 6:18).And for the Good Stuff:Trial Files (6:18 – 7:59).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-02-1307 minThe Rounds TableEpisode 105 - Intravenous Thrombolysis in Minor Ischemic Stroke with Intracranial OcclusionSend us a textWelcome back Rounds Table Listeners!We are back today with a solo episode with Dr. Mike Fralick!This week, he will discuss a paper exploring the role of intravenous thrombolytic therapy in patients with minor ischemic stroke and intracranial vessel occlusion. Here we go!Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open-label, phase 3 superiority trial (0:00 – 6:18).And for the Good Stuff:Trial Files (6:18 – 7:59).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-02-1307 minThe Rounds TableEpisode 102 - Oxygenation in Acute Respiratory Failure and Treatment of Ventricular TachycardiaSend us a textWelcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration, discuss two recent papers exploring oxygenation in acute respiratory failure and the use of ablation versus anti-arrhythmic medication for ventricular tachycardia. Two papers, here we go!High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients with Acute Respiratory Failure: The RENOVATE Randomized Clinical Trial (0:00 – 14:45).Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia (14:45 – 22:55).An...2025-01-2323 minThe Rounds TableEpisode 102 - Oxygenation in Acute Respiratory Failure and Treatment of Ventricular TachycardiaSend us a textWelcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration, discuss two recent papers exploring oxygenation in acute respiratory failure and the use of ablation versus anti-arrhythmic medication for ventricular tachycardia. Two papers, here we go!High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients with Acute Respiratory Failure: The RENOVATE Randomized Clinical Trial (0:00 – 14:45).Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia (14:45 – 22:55).An...2025-01-2323 minThe Rounds TableEpisode 100 - Conflicts of Interest in Peer ReviewingSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. David-Dan Nguyen, a Urology Resident at the University of Toronto, to chat about his recent study, "Payments by Drug and Medical Device Manufacturers to US Peer Reviewers of Major Medical Journals", that has been recently published in JAMA.Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-01-0319 minThe Rounds TableEpisode 100 - Conflicts of Interest in Peer ReviewingSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. David-Dan Nguyen, a Urology Resident at the University of Toronto, to chat about his recent study, "Payments by Drug and Medical Device Manufacturers to US Peer Reviewers of Major Medical Journals", that has been recently published in JAMA.Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2025-01-0319 minThe Rounds TableEpisode 98 - Perioperative Medicine with Dr. Kevin VenusSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Kevin Venus, a General Internist at Toronto Western Hospital, to chat about perioperative medicine!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2024-12-1329 minThe Rounds TableEpisode 98 - Perioperative Medicine with Dr. Kevin VenusSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Kevin Venus, a General Internist at Toronto Western Hospital, to chat about perioperative medicine!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods2024-12-1329 minThe Rounds TableEpisode 95 - HypertensionSend us a textWelcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike Fralick and Justin Boyle discuss two recent papers exploring the effect of sitting time reduction on blood pressure and the discontinuation of RAAS inhibition perioperatively. Two papers, here we go!Sitting Time Reduction and Blood Pressure in Older Adults (0:00 – 11:35).Discontinuation versus continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial (11:35 – 21:32).And for the Good Stuff:Summer McIntosh becomes 1st Canadian to win 3 gold medals at a si...2024-11-1524 minThe Rounds TableEpisode 95 - HypertensionSend us a textWelcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike Fralick and Justin Boyle discuss two recent papers exploring the effect of sitting time reduction on blood pressure and the discontinuation of RAAS inhibition perioperatively. Two papers, here we go!Sitting Time Reduction and Blood Pressure in Older Adults (0:00 – 11:35).Discontinuation versus continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial (11:35 – 21:32).And for the Good Stuff:Summer McIntosh becomes 1st Canadian to win 3 gold medals at a si...2024-11-1524 minThe Rounds TableEpisode 94 - Top Papers from the 2024 European Society of Cardiology CongressSend us a textWelcome back Rounds Table Listeners!We are back today with a special Rapid Fire Podcast!This week, Drs. Mike Fralick and Justin Boyle discuss top papers from the 2024 European of Society of Cardiology Congress. Here we go!Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease (0:00 – 9:25).Beta-Blocker Interruption or Continuation after Myocardial Infarction (9:25 – 13:52).Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (13:52 – 21:20).Continuation vs. Discontinuation of Renin-Angiotensin System Inhibitors Before Major Non-Cardiac Surgery (21:20 – 28:51).Of note, for prescribers in Ontario, there is now a limited...2024-10-3128 minThe Rounds TableEpisode 94 - Top Papers from the 2024 European Society of Cardiology CongressSend us a textWelcome back Rounds Table Listeners!We are back today with a special Rapid Fire Podcast!This week, Drs. Mike Fralick and Justin Boyle discuss top papers from the 2024 European of Society of Cardiology Congress. Here we go!Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease (0:00 – 9:25).Beta-Blocker Interruption or Continuation after Myocardial Infarction (9:25 – 13:52).Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (13:52 – 21:20).Continuation vs. Discontinuation of Renin-Angiotensin System Inhibitors Before Major Non-Cardiac Surgery (21:20 – 28:51).Of note, for prescribers in Ontario, there is now a limited...2024-10-3128 minThe Rounds TableEpisode 93 - Rare DiseasesSend us a textWelcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our new Medicine Pods collaboration, discuss two recent papers exploring the novel management of two rare diseases - ATTR Amyloidosis and Hereditary Angioedema. Two papers, here we go!Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis (0:00 – 14:15).Efficacy and Safety of Donidalorsen for Hereditary Angioedema (14:15 – 25:14).And for the Good Stuff:Medicine Pods! (25:14 – 26:23).Questions? Commen...2024-09-1326 minThe Rounds TableEpisode 93 - Rare DiseasesSend us a textWelcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our new Medicine Pods collaboration, discuss two recent papers exploring the novel management of two rare diseases - ATTR Amyloidosis and Hereditary Angioedema. Two papers, here we go!Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis (0:00 – 14:15).Efficacy and Safety of Donidalorsen for Hereditary Angioedema (14:15 – 25:14).And for the Good Stuff:Medicine Pods! (25:14 – 26:23).Questions? Commen...2024-09-1326 minThe Rounds TableEpisode 92 - The ERASe Trial with Dr. Dirk von LewinskiSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Dirk von Lewinski, an Interventional Cardiologist, Intensivist, and Scientist from the Medical University of Graz, to chat about his practicing changing trial!Questions? Comments? Feedback? We’d love to hear from you! @roundstable2024-09-0116 minThe Rounds TableEpisode 92 - The ERASe Trial with Dr. Dirk von LewinskiSend us a textWelcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Dirk von Lewinski, an Interventional Cardiologist, Intensivist, and Scientist from the Medical University of Graz, to chat about his practicing changing trial!Questions? Comments? Feedback? We’d love to hear from you! @roundstable2024-09-0116 minThe Rounds TableEpisode 89 - Tirzepatide, OSA, and ObesitySend us a textWelcome back Rounds Table Listeners!We are back today with a solo episode with Dr. Mike Fralick!This week, he will discuss a recent paper exploring the efficacy of tirzepatide in treating obstructive sleep apnea and obesity. Here we go!Tirzepatide for the Treatment of Obstructive Sleep Apnea and ObesityCheck out the New Motto!Questions? Comments? Feedback? We’d love to hear from you! @roundstable2024-07-1208 minThe Rounds TableEpisode 89 - Tirzepatide, OSA, and ObesitySend us a textWelcome back Rounds Table Listeners!We are back today with a solo episode with Dr. Mike Fralick!This week, he will discuss a recent paper exploring the efficacy of tirzepatide in treating obstructive sleep apnea and obesity. Here we go!Tirzepatide for the Treatment of Obstructive Sleep Apnea and ObesityCheck out the New Motto!Questions? Comments? Feedback? We’d love to hear from you! @roundstable2024-07-1208 minThe Rounds TableTBT - Intravenous IronSend us a textWelcome back Rounds Table Listeners!In this throwback episode, Drs. Mike Fralick and Justin Boyle discuss two papers exploring intravenous iron infusions in heart failure with iron deficiency and in reducing blood transfusion requirements in patients with hip fracture. Check it out below!Ferric Carboxymaltose in Heart Failure with Iron Deficiency (0:00 – 8:12).Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial) (8:12 – 19:00).And for the Good Stuff:Pop Culture Nostalgia (19:00 – 19:33).Thrombo Trial Files (19:33 – 20:48).Questions? Comments? Feedback? We’d love to he...2024-06-2121 minThe Rounds TableTBT - Intravenous IronSend us a textWelcome back Rounds Table Listeners!In this throwback episode, Drs. Mike Fralick and Justin Boyle discuss two papers exploring intravenous iron infusions in heart failure with iron deficiency and in reducing blood transfusion requirements in patients with hip fracture. Check it out below!Ferric Carboxymaltose in Heart Failure with Iron Deficiency (0:00 – 8:12).Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial) (8:12 – 19:00).And for the Good Stuff:Pop Culture Nostalgia (19:00 – 19:33).Thrombo Trial Files (19:33 – 20:48).Questions? Comments? Feedback? We’d love to he...2024-06-2121 minThe Rounds TableTBT - Dermatomyositis and the HALT-IT TrialSend us a textWelcome back Rounds Table Listeners!In this throwback episode, Drs. John and Mike Fralick discuss two papers – one, exploring IVIG in the treatment of dermatomyositis, and the second investigating the effect of tranexamic acid in patients with acute gastrointestinal bleeding.Trial of Intravenous Immune Globulin in Dermatomyositis (0:00 – 8:38).Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international, randomised, double-blind, placebo-controlled trial (8:38 – 18:04).And for the Good Stuff:Alberta using humour to attract workers (18:04 – 18:50).CBME in Residency Educatio...2024-05-2421 min