Shows
In the Interim...The Legend of I-SPY 2 - Part BIn this episode, Dr. Don Berry and Dr. Scott Berry provide an in-depth account of I-SPY 2, focusing on the trial’s use of the “time machine” methodology—a Bayesian solution allowing bridging across arms to inform ongoing analyses. The discussion details how predictive probabilities and adaptive randomization shaped pivotal decisions, including the handling of Pertuzumab’s approval and Neratinib’s subtype-specific performance. This episode also documents the technical and operational contributions of Laura Esserman, Anna Barker, Janet Woodcock, Meredith Buxton, and Ashish Sanil, clarifying the roles that enabled the platform’s success and broader impact on subsequent adaptive trials.Key Highl...
2025-07-2125 min
PharmaTalkRadioWhat to Expect at the CRAACO: Clinical Research as a Care Option 2025 EventConference Forum Director Valerie Bowling and CRAACO Producer Danny McCarthy break down what to expect at the 2025 CRAACO program. This podcast covers the keynotes, panels and key themes for this year's event, including: How to develop a clinical research program within a community cancer center, with Dr Brian Slomovitz, Mount Sinai Medical Center Miami BeachTurning clinical environments into learning health systems, with Dr Laura Esserman, UCSF Carol Franc Buck Breast Cancer CenterHow to better partner with multiple location health system structures for clinical trials Addressing medical staff shortages and challenges to support clinical researchThe impact of clinical trial participation on...
2025-07-0810 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 2: Why is Cancer so Expensive? With Special Guest Dr. Laura EssermanJohn Marshall, MD: Hey everybody, John Marshall for Oncology Update. Believe it or not, second episode. They let me do a second one. There's bad judgment on their part.ASCO Buzz[00:00:13]We're just back from ASCO, so you know how everybody's doing. You're still trying to pile out of your emails and figure out if you're actually going to get reimbursed for that dinner or not try for it. You never know. It might work out. Let's start and kind of reflect a bit on this meeting, that is ASCO. You k...
2025-02-2027 min
Less RadicalBONUS: What Could Be Better Than a Mammogram?Mammograms were introduced fifty years ago. Recommendations for women to have annual screening mammograms began thirty years ago. The hope was that by finding breast cancer early, we could drastically reduce the number of women dying from breast cancer. And in some ways, we have been successful. The problem with annual screening mammograms is that it is based on the assumption that every breast cancer follows the pattern - progressing from a pre-cancerous lesion to a more aggressive tumor in a logical, linear way. Today, we know this isn’t true. Yes, some cancers are sl...
2024-12-1134 min
ScrubcastBreast Cancer Surgery & Innovative Rehabilitation with Dr. Kim StoneIn this episode, host Rachel Baker sits down with Dr. Kim Stone, a clinical associate professor in the surgical oncology breast section at Stanford University. Together, they discuss Dr. Stone’s journey into breast surgery, the importance of early mammograms, and an exciting new project utilizing virtual reality for patient rehabilitation.
⏰ Episode Highlights:
• [00:00:00] Introduction to Dr. Kim Stone
• [00:01:00] Dr. Stone’s passion for breast surgery
• [00:02:00] Mammogram guidelines—When should you start?
• [00:06:00] The impact of breast cancer surgery on upper extremity function
• [00:10:00] Using Virtual Reality for patient rehab—How did it start?
• [00:12:00] Assessing the feasibility of VR in rehabilitation
• [00:15:00] Celebrating women in surgery: Dr. Laura Es...
2024-10-0117 min
Biz Book Pub Hub PodcastEncore OTS 199: Vulnerability to Success – Hope TimberlakeToday’s guest focuses on the communication side of leadership.Through her warmth and humor, she helps people to become better communicators, influencers and leaders. They recognize gaps, build on strengths, and become more effective professionals.Over the last 10 years, she has worked with clients across a variety of sectors to enhance their performance and workplace influence. Her clients have included AirBnB, Bank of America, Microsoft, Nestlé, and Visa.She is the founder of Forte Consulting inspiring extraordinary performances from individuals and teams.
2024-07-0247 min
Get Real with Jim WeissEpisode Five: Dr. Laura Esserman and Dr. Steve Birrell (Pioneering Androgen Therapies for Breast Cancer & Should All Breast Cancers Be Called Cancer?)In this episode, you'll meet Dr. Laura Esserman and Dr. Steve Birrell, who are collaborating to change the breast cancer treatment paradigm. This topic is more relevant than ever, given recent developments in the world of celebrities and influencers, such as Olivia Munn, who announced she had a double mastectomy for Luminal B breast cancer. Dr. Esserman is a force of nature in breast cancer. Since 1993, she’s worked at UCSF as a surgeon and oncology specialist, and co-lead of their Breast Oncology Program. She’s gained an audience by publishing over 400 peer-reviewed articles and appearing in mainstream news, such...
2024-06-0545 min
Investigating Breast CancerThe Effects of a High-Fiber Diet in Early-Stage Breast Cancer with Dr. Laura EssermanDr. Laura Esserman talks about her current research that examines how fiber shapes the gut microbiome, potentially improving the response to immune agents in women newly diagnosed with breast cancer.
Her prior research looked at how immune cells in tumors influence tumor response to immune drugs, and she believes the gut microbiome plays a key role in this complex system.
A BCRF investigator since 1998, Dr. Esserman is an internationally recognized breast surgeon, breast oncology specialist, and personalized medicine visionary.
2024-01-1728 min
Checking In With Check For A LumpThe WISDOM Study: Transforming Breast Cancer Screening, Detection & Prevention through Personalized Risk AssessmentHear from Dr. Laura Esserman as we talk about how the understanding of breast cancer has shifted recently, if all women have the same risk of getting breast cancer, and how women can learn what their risk is. Each podcast will have a Check for a Lump challenge.
2023-12-1900 min
Beyond The Paper Gown PodcastBeyond the Mammogram: New Ways to Detect and Prevent Breast Cancer
In this podcast episode, Mitzi Krockover, MD, engages in an eye-opening conversation with the dynamic Laura Esserman, MD, MBA, Endowed Chair in General Surgery, Director of the UCSF Breast Care Center, shedding light on the revolutionary Wisdom Study. Dr. Esserman passionately advocates for a paradigm shift in breast cancer screening, challenging the one-size-fits-all approach. The Wisdom Study, with its audacious goal of enrolling 100,000 diverse women, promises to transform screening methods tailored to individual risk profiles. Dr. Esserman's fervor for prevention strategies that consider personal history, genetics, and more sparks excitement for a proactive approach to stop breast cancer in...
2023-12-1442 min
Grey Matter with Michael KrasnyDr. Laura Esserman - Aspiring to BetterWe recently spoke with Dr. Laura Esserman, a leading internationally recognized surgeon and breast cancer oncologist at the University of California Medical School, where she serves as director of the Carol Franc Buck Breast Care Center. We discussed the need to redefine cancer and the need for personalized patient centered care in health care, as well as a range of other issues related to public policy and their impact on the delivery of clinical care. Join us!
2023-11-2858 min
Oncology for the Inquisitive Mind61. Fireside Chats: What We Call "Cancer"Between 1933 and 1944, Americans huddled around their radios to listen to the words of Franklin Delano Roosevelt, the 32nd President of the United States. Covering topics ranging from the 1936 recession to World War II, FDR titled these addresses "Fireside Chats", giving very high-concept topics a more personal, intimate feel. Let it never be said that Oncology for the Inquisitive Mind is above shamelessly cribbing ideas from history.In this series, on the first Wednesday of each month, Josh and Michael will go away from their usual format of data dissection. They will instead turn their attention to...
2023-09-0625 min
Pfeffer on PowerEp 16 – Dr. Laura Esserman, Professor of Surgery and Radiology UCSF, Director of the UCSF Breast Care ClinicLearn more about Jeffrey Pfeffer and where you can buy or listen to his books:
JeffreyPfeffer.com
Episode 16 – Dr. Laura Esserman, Professor of Surgery and Radiology UCSF, Director of the UCSF Breast Care Clinic
Dr. Laura Esserman is a leading figure in the transformation of American medicine. Named one of Time Magazine’s 100 Most Influential People in the World, Laura is dedicated to increasing the speed at which we learn about new cancer drugs and treatments. She discusses her transformation into becoming a more effective version of herself through storytelling and cultivating empathy with oppo...
2023-03-1421 minA Vision for the Integration of Clinical Research and CareDrs Janet Woodcock and Laura Esserman discuss why integrating clinical research and care is so critical and explore how we can get patients more access to clinical trials. Together they address:
What is missing for the vision of integrating care and researchReal world dataPlatform trials and adaptive design solutionsHarmonizing data collectionNew models for covering costDeveloping a centralized IRBSimplifying the trial activation processIntegrating data collection with clinical care help from community settingsEarly endpoints and their ability to drive de-escalation and escalationWorkforce developmentMindsets, models, tools and more
Speakers:
Laura Esserman, MD, Professor of Surgery & Radiology, University of California, San Francisco / Director, UCSF Carol...
2022-11-1135 min
PharmaTalkRadioA Vision for the Integration of Clinical Research and CareDrs Janet Woodcock and Laura Esserman discuss why integrating clinical research and care is so critical and explore how we can get patients more access to clinical trials. Together they address: What is missing for the vision of integrating care and researchReal world dataPlatform trials and adaptive design solutionsHarmonizing data collectionNew models for covering costDeveloping a centralized IRBSimplifying the trial activation processIntegrating data collection with clinical care help from community settingsEarly endpoints and their ability to drive de-escalation and escalationWorkforce developmentMindsets, models, tools and more Speakers: Laura Esserman, MD, Professor of Surgery & Radiology, University of California, San Francisco / Director, UCSF Carol...
2022-11-1134 min
Precision Medicine Forum Podcast013 Pushing treatments for Breast Cancer forwards - Dr. Laura EssermanThe buzz around the potential of Precision Medicine continues as new technologies, more powerful computing and our ability to store, share and interpret Big Data increases. On these podcasts Steve Coldicott and Scott Buckler chat about all aspects of the industry with patients, healthcare industry and research professionals about creating personalised medicines for each and every one of us.
On this episode of Precision Medicine Forum Podcast, Steve's chatting with Dr Laura Esserman, who's the Principal Investigator at The WISDOM Study.
The WISDOM Study brings together 100,000 diverse women from across the US to find the...
2022-10-0446 min
Behind The Knife: The Surgery PodcastJournal Review in Breast Surgery: Evolution of DCIS ManagementDuctal carcinoma in situ, or DCIS, is a precursor lesion to invasive breast cancer; however, not all DCIS becomes invasive cancer. Given our inability to accurately determine which DCIS lesions will progress, current clinical management consists of surgical resection for everyone with the possible additions of radiation and endocrine therapy. Multiple clinical trials and leaders in the field of breast surgical oncology are challenging our assumptions about the uniform approach to DCIS and are attempting to design treatment based on biology— tune in to hear about the evolving approach to management of DCIS!
Hosts:
Alexa Glencer, MD
Mi...
2022-08-1836 min
SoundPracticeDr. Laura Esserman, The Wisdom Study, and Breast Cancer RiskAlthough great strides have been made in diagnosing and treating breast cancer, 40,000 Americans die of the disease each year. Today on SoundPractice, host Mike Sacopulos discusses The Wisdom Study with Laura J. Esserman, MD, MBA. Dr. Esserman the Director of the UCSF Carol Franc Buck Breast Care Center at UC San Francisco, a professor of Surgery & Radiology at UCSF, and a practicing surgeon and breast cancer oncology specialist.
The WISDOM Study – Women Informed to Screen Depending On Measures of risk, seeks to bring together 100,000 diverse woman from across the United States to find the safest and most effective way to detect bre...
2022-04-2131 min
Handle with CARE: Cancer & BeyondThe WISDOM Study with Dr. Lisa MadlenskyThe groundbreaking WISDOM Study, founded by Dr. Laura Esserman, is testing a personalized approach to screening compared to annual mammograms. Dr. Madlensky describes why this is so important and how women in the US between the ages of 40-74 can get involved. Please visit www.wisdomstudy.org for more information. #hwcarepodcast #genetics #breastcancerresearch #wisdomstudy #breastcancer
2021-12-2950 min
JAMA Oncology Author InterviewsAssessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-Risk Breast CancerInterview with Laura J. Esserman, MD, and W. Fraser Symmans, MD, authors of Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial
2021-09-1634 min
When Science SpeaksLeveraging Personalized Medicine for Breast Cancer Prevention and Treatment with Laura Esserman, MDBreast cancer is preventable and yet, many women all over the world still get it. The question now is, how can you prevent and reduce your risks of developing breast cancer? Laura Esserman, MD is determined to change things through the WISDOM (Women Informed to Screen Depending on Measures of Risk) study. Laura Esserman, MD is a Professor of Surgery and Radiology at the University of California San Francisco (UCSF), and she is also the Director of the UCSF Breast Care Clinic. Her work in breast cancer spans the spectrum from basic science to public policy issues a...
2020-05-1542 minKeynote: Surgeon’s Perspective on Integrating Clinical Care & Clinical ResearchIn this podcast, you will hear a keynote presentation from the 2019 Clinical Research as a Care Option (CRAACO) conference. Dr Laura Esserman, the architect behind the I-SPY 2 TRIALTM has achieved remarkable progress with this clinical trial in improving the outcomes of early stage, breast cancer for patients who are at high risk for early recurrence. I-SPY 2 is also impacting far beyond breast cancer by increasing efficiencies that promise to accelerate the development and delivery of more effective therapies for other cancer types and a range of other diseases. This would not be possible without the integration of care and research...
2020-02-1440 minPharmaTalkRadioKeynote: Surgeon’s Perspective on Integrating Clinical Care & Clinical ResearchIn this podcast, you will hear a keynote presentation from the 2019 Clinical Research as a Care Option (CRAACO) conference. Dr Laura Esserman, the architect behind the I-SPY 2 TRIALTM has achieved remarkable progress with this clinical trial in improving the outcomes of early stage, breast cancer for patients who are at high risk for early recurrence. I-SPY 2 is also impacting far beyond breast cancer by increasing efficiencies that promise to accelerate the development and delivery of more effective therapies for other cancer types and a range of other diseases. This would not be possible without the integration of care and research...
2020-02-1439 min
The CanSurvivor Network#bOObs for Life with Sylvia Kouveli & Ted Meyer | Episode 054Universe, what’s good?! Today's guests to round out #BreastCancerActionMonth are Sylvia Kouveli and Ted Meyer, who have come together in Los Angeles to create #bOObs for Life, a compilation of visually portrayed stories about physical trauma, personal struggle, survival, and the celebration of life. The exhibition is presented with support from the American Cancer Society.
Before the interview begins, Kelsey has an important announcement about her treatment status. She will be in treatment for another five years and encourages all who qualify to participate in the Breast Cancer Index test. Speaking of screening, Kelsey was on an...
2019-11-1300 minIntegrating Care and Research with Dr Laura EssermanIn this podcast, Valerie Bowling, Executive Director of the Conference Forum, interviews Dr Laura Esserman, breast cancer surgeon and researcher at the University of California, San Francisco. Dr Esserman shares her thoughts on how we can move towards uniting care and clinical research and the future of how medicine should be practiced.
2019-03-2708 minPharmaTalkRadioIntegrating Care and Research with Dr Laura EssermanIn this podcast, Valerie Bowling, Executive Director of the Conference Forum, interviews Dr Laura Esserman, breast cancer surgeon and researcher at the University of California, San Francisco. Dr Esserman shares her thoughts on how we can move towards uniting care and clinical research and the future of how medicine should be practiced.
2019-03-2707 min
The Readout LoudEpisode 49: Painkiller racketeering, the limits of genetic tests, and pharma's day on the HillIs pharma about to have its Big Tobacco moment? Are we overestimating human genetics? And can sales reps rap?
We discuss all that and more on the latest episode of “The Readout LOUD,” STAT’s biotech podcast. First, Boston Globe reporter Jonathan Saltzman joins us to discuss the case against Insys Therapeutics, the maker of a powerful painkiller now accused of running a nationwide racketeering scheme. Then Dr. Laura Esserman of the University of California, San Francisco, comes on to break down the debate over genetic testing for cancer risk. And then we give you the need-to-know on an upcoming Senate...
2019-02-2123 min
SpitIs Prevention the Key to Beating Breast Cancer? with Rita Wilson, Dr. Laura Esserman, Katie Thiede and Sara AltschuleOne in eight US women will develop invasive breast cancer over the course of her life, and while we’ve seen a decrease in deaths thanks to advances in screening, treatment and awareness, that’s still too high. On today’s show, we ask the crucial question: what can we do to combat this disease, and how can our self-awareness of our risk, our genetic predisposition and our options aid in this effort? We have gathered an amazing group of women, with varied experiences and viewpoints to examine this: Actor, musician, activist and breast cancer survivor Rita Wilson; renowned resear...
2018-12-061h 07
UC Office of the PresidentQuality: Do We Know It When We See It?Moderator: Dr. Peter Pronovost, Sr. Vice President for Patient Safety and Quality, Director of the Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine. Panelists: Sheila Antrum, Dr. Robert Cherry, Dr. Laura Esserman, Dr. Julie A. Freischlag Series: "Quality Improvement and Health Care Reform" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 32067]
2017-04-2500 minUC Office of the President (Audio)Quality: Do We Know It When We See It?Moderator: Dr. Peter Pronovost, Sr. Vice President for Patient Safety and Quality, Director of the Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine. Panelists: Sheila Antrum, Dr. Robert Cherry, Dr. Laura Esserman, Dr. Julie A. Freischlag Series: "Quality Improvement and Health Care Reform" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 32067]
2017-04-2500 min
One-on-One with Eric TopolIconoclastic Breast Surgeon Laura Esserman Challenges the Status QuoFrom screening to treatment, breast cancer specialist Laura Esserman is on a quest to individualize patient care, and in doing so she is challenging a number of long-standing practices in cancer care.
2016-08-0823 min
Author in the Room™ InterviewsJAMA: 2009-10-21, Vol. 302, No. 15, Author in the Room™ Audio InterviewInterview with Laura Esserman, MD, MBA, author of Rethinking Screening for Breast Cancer and Prostate Cancer. Summary Points: 1. The effectiveness of screening depends on the underlying biology of cancer. Routine mammographic screening works best for slow to moderate growth tumors, most common in women 50-74 and explains why the Preventive Services guidelines actually make sense. 2. There are ways that we can improve screening today. Trained mammographers find the most cancers and have the fewest false positives. Offering follow-up as an option for low risk mammographic lesions will decrease false positives. Screening the populations who benefit most will also avoid false...
2009-12-1752 min