Shows
DITLSocial Time Is Vital As We Age, Says Longevity Expert Dr. Leonard GuarenteName: Dr. Leonard Guarente (@elysiumhealth)Occupation: World-renowned longevity expert, dubbed the "grandfather of the booming longevity movement," Novartis Professor of Biology at MIT, and co-founder and chief scientist at Elysium Health, a science-backed supplement company.Day: Complex carbohydrates at breakfast to avoid insulin spikes, prioritizing balance exercises, and enjoying socializing with family at dinner.For more DITL, follow along online:Instagram: @ditlpod, @paigemport, and @dearmediastudio.YouTube: @dearmediastudioTikTok: @dearmediaProduced by Dear Media.This...
2026-01-2955 min
The Human Upgrade: Biohacking for Longevity & PerformancePhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies)Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on...
2025-08-191h 08
Behind the BastardsPart One: Dire Wolves, Dr. George Church & The De-Extinction GriftRobert walks Langston Kerman through the story of Dr. George Church, a very real scientist who co founded the company making bullshit claims of "de extincting" dire wolves. (2 Part Series) Sources: George Church, Colossal W*nker – For Better Science Can Gene Therapy Slow Ageing in Dogs? - Gowing Life Never-ageing Anti-aging to cure COVID-19 – For Better Science The original sins of Leonard Guarente – For Better Science Jeffrey Epstein Hoped to Seed Human Race With His DNA - The New York Times Biologist George Church apologizes for contacts with Jeffreyticl Epstein Genetics Company Wants To Bring Iconic Tasmanian Tiger Back From E...
2025-06-031h 14
Behind the BastardsPart One: Dire Wolves, Dr. George Church & The De-Extinction GriftRobert walks Langston Kerman through the story of Dr. George Church, a very real scientist who co founded the company making bullshit claims of "de extincting" dire wolves. (2 Part Series) Sources: George Church, Colossal W*nker – For Better Science Can Gene Therapy Slow Ageing in Dogs? - Gowing Life Never-ageing Anti-aging to cure COVID-19 – For Better Science The original sins of Leonard Guarente – For Better Science Jeffrey Epstein Hoped to Seed Human Race With His DNA - The New York Times Biologist George Church apologizes for contacts with Jeffreyticl Epstein Genetics Company Wants To Bri...
2025-06-031h 14
Claves del día - JOSE VIZNER - Negocios TVClaves del día: El plan oculto de Trump con los aranceles, Europa en duda y vivirás más de 100 añosClaves del día: El plan oculto de Trump con los aranceles, Europa en duda y vivirás más de 100 añosDía clave: el mercado de celebración porque parece que los aranceles de Donald Trump serán más selectivos. No golpeará a la automoción ni a los semiconductores. Subidas generalizadas, salvo en Asia. Wall Street Journal, Financial Times y Bloomberg ya avisan que el 2 de abril no habrá ningún tsunami arancelario. Es el efecto de recuperación de un mercado que ve que Trump ha golpeado verbalmente únicamente. Día de recuperación...
2025-03-2450 min
The Optispan Podcast with Matt KaeberleinMatt Kaeberlein reflects on "David Sinclair’s Longevity Lie" | 62 - Longevity Reacts #5
Subscribe to our channel: https://www.youtube.com/@optispan
Check out Scott Carney's channel: https://www.youtube.com/@sgcarney
Related episodes:
The True Story of David Sinclair's Longevity Lie: https://www.youtube.com/watch?v=xQrXs7CxIjk
DON'T Take Resveratrol Until You Watch This Video: https://youtu.be/MmIBdqsQYfw
Scientists Debate How to Live Longer & Longevity Drugs: https://youtu.be/EebH_taOlAA
An introduction to the study of RAPAMYCIN: https://youtu.be/czx_-DqnnrQ
In this episode, Matt and Nick react to investigative journalist and author Scott Carney's video describing what he calls "David Sinclair's longevity lie" in the...
2024-09-051h 06
Beyond Lifespan - Dein Fast-Track zu mehr GesundheitNAD – ein kleines Coenzym mit großer WirkungDas Wundermolekül NAD: Schlüssel zu Energie und Langlebigkeit
In dieser Folge von „Beyond Lifespan“ widmen wir uns einem Shooting-Star der Longevity-Forschung. Und zwar dem Molekül NAD+ (Nikotinamid-Adenin-Dinukleotid), einem Coenzym, das eine zentrale Rolle in der Energieproduktion unserer Zellen spielt. Wir diskutieren, wie NAD im Körper erzeugt wird, welche verschiedenen Formen es gibt und wie es unseren Energiestoffwechsel antreibt. Außerdem beleuchten wir, warum NAD-Spiegel mit dem Alter sinken und wie dieser Rückgang mit gesundheitlichen Beschwerden in Verbindung steht. Sehr spannend ist zudem der Exkurs zu den Sirtuinen - einer Familie von Genen, die Langlebigkeit begünstige...
2024-04-1142 min
Terra API Podcast - Stay Fit, Stay ConnectedFounder of Inside Tracker: Gil BlanderIn this podcast, we connected with Gil Blander, founder of InsideTracker, a longevity company that creates evidence-based solutions that are simple, clear, and actionable.
Gil explains his personal motivations for working with longevity and how he witnessed a close family member facing mortality at a young age. He discusses his journey of studying biology that led him to earn his PhD from the Weizmann Institute of Science and work at one of the most renowned aging labs in the world, the Leonard Guarente Lab, at MIT.
Moreover, Gil shares his extensive scientific knowledge of how blood biomarkers and genetics affect...
2023-11-2248 min
The Thomistic InstituteThe Ethics of Human Gene Editing with CRISPR | Fr. Nicanor Austriaco, O.P.This talk was given on October 5th, 2022 at Dartmouth College.
For more information please visit thomisticinstitute.org.
About the speaker:
Fr. Nicanor Austriaco, O.P., completed his Bachelor’s Degree (B.S.E.) in Bioengineering, summa cum laude, at the University of Pennsylvania, and then earned his Ph.D. in Biology from M.I.T. in the laboratory of Professor Leonard Guarente, where he was a fellow of the Howard Hughes Medical Institute (HHMI). He was ordained a priest in the Order of Preachers in May of 2004. He completed his Pontifical License in Sacred Theology (S.T.L.) in Mo...
2023-04-071h 07
THE ONE'S CHANGING THE WORLD -PODCASTHEALTHY LONGEVITY- DR.BRIAN KENNEDY : PROF & DIR OF THE CENTER FOR HEALTHY AGING AT NUS-SINGAPORE#agereversal #science #biotechnology #ageing #health #podcast #toctw
Dr. Brian Kennedy is internationally recognized for his research in the basic biology of aging and as a visionary committed to translating research discoveries into new ways of detecting, delaying, preventing, and treating human aging and associated diseases. He is a Distinguished Professor in Biochemistry and Physiology at the Yong Loo Lin School of Medicine at the National University Singapore (NUS) and serves as Director of (1) the Centre for Healthy Longevity at the National University Health System, (2) the Healthy Longevity Translational Research Programme and (3) the Asian Centre for Reproductive Longevity a...
2023-01-0234 min
Movimento Estensione VitaVIDEO:Il rapporto tra le Sirtuine, il NAD e l'invecchiamentoIl professor David Sinclair, uno dei piu' importanti ricercatori nel campo dell'antiage, dell'anti-invecchiamento, vede le Sirtuine come percorso metabolico estremamente importante per la biologia dell'invecchiamento.
Le Sirtuine furono inizialmente scoperte nel lievito e successivamente l'interesse verso questo particolare tipo di sostanze, coinvolte in molti processi metabolici, e' cresciuto quando si e' visto che l'espressione aumentata della Sirtuina due aumentava la durata della vita del lievito del trenta percento.
David Sinclair ha continuato il suo lavoro nel laboratorio del professor Leonard Guarente per vedere se questi risultati potevano essere trasferiti anche ad altri modelli animali.
2022-10-0808 min
Movimento Estensione VitaSCIENZA-Il rapporto tra le Sirtuine, il NAD e l'invecchiamentoIl professor David Sinclair, uno dei piu' importanti ricercatori nel campo dell'antiage, dell'anti-invecchiamento, vede le Sirtuine come percorso metabolico estremamente importante per la biologia dell'invecchiamento.
Le Sirtuine furono inizialmente scoperte nel lievito e successivamente l'interesse verso questo particolare tipo di sostanze, coinvolte in molti processi metabolici, e' cresciuto quando si e' visto che l'espressione aumentata della Sirtuina due aumentava la durata della vita del lievito del trenta percento.
David Sinclair ha continuato il suo lavoro nel laboratorio del professor Leonard Guarente per vedere se questi risultati potevano essere trasferiti anche ad altri modelli animali.
2022-10-0808 min
Mind & MatterCellular Aging, Oxidative Stress, Antioxidants, Life Extension & Health Supplements | Leonard Guarente | #69Nick talks to biologist Dr. Leonard Guarente about the biology of aging, life extension, health supplements, and related topics. Dr. Guarente is a Professor of Biology at MIT, where his lab has studied the molecular and cellular mechanisms of aging for many years. He is also the co-founder and Chief Scientist of Elysium Health, which uses the science of aging to develop health supplements to combat age-related decline and technologies to help consumers understand their rate of aging. Nick and Dr. Guarente discussed many topics related to aging, including: how and why aging occurs; whether humans can achieve immortality; N...
2022-05-051h 26
Mind & MatterCellular Aging, Oxidative Stress, Antioxidants, Life Extension & Health Supplements | Leonard Guarente | 69Send a textNick talks to biologist Dr. Leonard Guarente about the biology of aging, life extension, health supplements, and related topics. Dr. Guarente is a Professor of Biology at MIT, where his lab has studied the molecular and cellular mechanisms of aging for many years. He is also the co-founder and Chief Scientist of Elysium Health, which uses the science of aging to develop health supplements to combat age-related decline and technologies to help consumers understand their rate of aging. Nick and Dr. Guarente discussed many topics related to aging, including: how and why a...
2022-05-051h 26
POD OF JAKE#101 - GIL BLANDERGil is the Founder and Chief Scientific Officer at InsideTracker. He is internationally recognized for his research in the biology of aging and translating research discoveries into new ways of detecting and preventing age-related conditions. Gil received a Ph.D. in biology from the Weizmann Institute of Science and completed his Post Doctoral fellowship at MIT where he worked in Leonard Guarente's lab alongside David Sinclair and others alike. Follow Gil on Twitter @gblander1.
[2:18] - How Gil’s early interest in biology led him to a focus on longevity
[10:01] - InsideTracker’s model for predicting life...
2022-04-1454 min
Primary Care CuresEpisode #55 – Aging is Actually a Disease, Not a Natural State. It is Likely Reversible. WHO Agrees Thanks to NYT Best-Seller and Harvard researcher, Dr. David Sinclair
In this episode Ron chats with the brilliant expert in aging Dr. David Sinclair. Here David discusses is work into understanding aging and how to slow it down. He also discusses the safety of different approaches, the importance of eating less frequently, when humans can expect to have their lifespans significantly increased, and more.
David A. Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He is best known for his work on understanding wh...
2020-02-1930 min
Psychologists Off the Clock125. Why We Age and the Science of Longevity with David SinclairWhat if you could slow down the clock on your aging? According to aging expert and Harvard geneticist, Dr. David Sinclair, we now have the knowledge and technology to live longer lives, healthier. In his revolutionary research, Dr. Sinclair has identified mechanisms behind aging giving us clues into the behaviors and molecules that can potentially extend life.
Listen and Learn:
Why is aging a disease and how can it be slowedWhat are longevity genes and what role do they play in healthWhat is epigenetics and how does it relate to aging and healthWhat is hormesis and why is being too co...
2020-02-0649 minPsychologists Off the Clock125. Why We Age and the Science of Longevity with David SinclairWhat if you could slow down the clock on your aging? According to aging expert and Harvard geneticist, Dr. David Sinclair, we now have the knowledge and technology to live longer lives, healthier. In his revolutionary research, Dr. Sinclair has identified mechanisms behind aging giving us clues into the behaviors and molecules that can potentially extend life.
Listen and Learn:
Why is aging a disease and how can it be slowedWhat are longevity genes and what role do they play in healthWhat is epigenetics and how does it relate to aging and healthWhat is hormesis and why is being too co...
2020-02-0649 min
The Armen Show231: David A. Sinclair | Anti-Aging Research And Understanding In “Lifespan”
When it comes to anti-aging research, Dr. David A. Sinclair of Harvard Medical School is on the forefront of research and innovation. He joins on episode 231 to discuss his new book Lifespan: Why We Age – and Why We Don’t Have To.
Dr. Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He is best known for his work on understanding why we age and how to slow its effects. He obtained his Ph.D. in Molecu...
2019-09-3034 min
Running: A FEVERRAF125: Basis - The Anti-Aging Supplementhttp://RunningAFEVER.com In the 1980's, Leonard Guarente began doing anti-aging research at MIT. He's a biologist, and his major discovery was finding a gene that controls aging by experimenting with yeast. Subsequent supporting research has been done on rats as well. In the 1980's, Leonard Guarente began doing anti-aging research at MIT. He's a biologist, and his major discovery was finding a gene that controls aging by experimenting with yeast. Subsequent supporting research has been done on rats as well. There are 2 important substances at work here. Sirtuins, a protein that regulates...
2019-02-2009 min
LifeMinute Health & WellnessManage Your Health in 2019The New Year means another year older, but cutting-edge research and groundbreaking innovation is changing the way we age. Practicing healthy eating and an active lifestyle are important, but the secret to good health at every age may already be within our bodies. Laurie Jennings, Deputy Editor at Good Housekeeping and Leonard Guarente, PhD, Chief Scientist at Elysium Health talked to us about the science behind long-term health and shared their best tips for adding life to your years.
2019-01-1003 min
How to Live to 200 PodcastUnlocking the Longevity Secrets of Man’s Best FriendMatt Kaeberlein – Longevity Expert Our guest today is Matt Kaeberlein, Ph.D., a globally recognized researcher and expert in the biology of aging. Dr. Kaeberlein’s research is based around the premise that understanding the molecular mechanisms of aging will lead to interventions that slow the onset and progression of age-related chronic conditions, such as cancer, diabetes, kidney disease, heart disease, Alzheimer’s and others. Dr. Kaeberlein received his Ph.D. from the Massachusetts Institute of Technology in 2002 advised by Leonard Guarente, and did his post-doctoral work with Stanley Fields in the Department of Genome Sciences at the Un...
2018-12-1152 min
The Peter Attia DriveDavid Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of agingIn this episode, David A. Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, provides insight into why we age and how to slow its effects based on his remarkable work on the role of sirtuins and NAD in health and diseases. He also presents the case that stabilizing the epigenetic landscape may be the linchpin in counteracting aging and disease. We discuss: How and why David moved from Australia to Leonard Guarente's lab at MIT [7:30]; Sirtuins a...
2018-11-051h 41
How to Live to 200 PodcastNutrition and Bio-Hacking w/ Martin Tobias, CEO, Bulletproof LabsMartin Tobias is the CEO of Bulletproof Labs, the CEO of Upgrade Labs and the co-founder of People For Cause, Element 8 Angels, and MGT Investments. He’s served on the board of directors for Cloudmark and Tippr, and co-founded numerous startups, including Kashless, Imperium Renewables, and Loudeye Technologies. He was a partner at Ignition Partners, a venture capital firm in Seattle, and previously served as an executive at Microsoft. In addition to being an experienced technology executive, Martin is a health enthusiast and an advocate for people taking control of their own biology. Bulletproof Labs is a hi...
2018-07-2452 minHow to Live to 200 PodcastBio-Marker Tracking w/ Gil Blander, PhD, Founder & Chief Science Officer, InsideTrackerGil Blander, Ph.D., Founder & Chief Science Officer of InsideTracker, joins T.A. for a conversation on blood biomarkers and performance optimization. Gil Blander is the Chief Science Officer and co-founder of InsideTracker, company dedicated to providing personalized health and wellness recommendations through blood analytics. Gil received his Ph.D. in biology from the Weizmann Institute of Science and completed his Doctoral fellowship at MIT. Gil is widely recognized as an expert in the science of aging and leads a team of specialists in nutrition and exercise physiology. InsideTracker is designed for people that want...
2018-07-1042 min
Let's Just Talk!Keeping our water safe/Fountain of YouthRobert Montenegro, Executive Vice President – Water Utility/Municipal at Grundfos discusses The Role and Importance of Water Utilities in Keeping Our Water Safe. Dr. Leonard P. Guarente - Director of MIT's Glenn Laboratory for the Science of Aging and Chief Scientist of Elysium Health discusses the scientific search for extended youth, . 3rd guest Lawrence Allen discusses the launch today the newest series with Kathryn Raaker, Elizabeth Bromwell: Chronicles of an Expat Spy. Volume 1This show is broadcast live on Thursday's 2PM ET on W4CY Radio – (www.w4cy.com) part of Talk 4 Radio (http://www.talk4radio.com...
2017-06-3049 min
Big Picture ScienceNo Expiration DateWe all have to go sometime, and that final hour is the mother of all deadlines. But scientists are working to file an extension. Discover how far we can push the human expiration date.Plus, the animal with the shortest lifespan and the chemistry that causes your pot-roast to eventually clothe itself in fuzzy green mold.Also, a clock that won’t stop ticking (for 10,000 years) and our love-hate relationship with that long-lived hydrocarbon that keeps our snack cakes fresh: plastic!Guests:
Martin Bucknavage- Senior Food Safety Extension Associate, Department of Food Sc...
2012-11-1954 min
Gab With the Gurus ShowBe 120 and Feel Like 50: Get the Scoop on Film "To Age or Not to Age"Imagine a 120-year-old living like today's 50 year-olds. Is it possible? Yes, according to the scientists in Robert Kane Pappas' new film, "To Age or Not to Age." Get ready for a provocative Gab with the Gurus Radio Show with director Pappas and Dr. Leonard Guarente. You'll learn that aging and death are not the absolutes we once thought they were. "To Age or Not to Age" tracks the pioneers in the field of anti-aging research at Harvard, MIT, Cambridge and other research centers. The scientists featured in the film have found the means to postpone and possibly mitigate diseases...
2010-07-1529 min
Futures in Biotech (Audio)Dr. Leonard P. Guarente on Aging
Why do living things age? What genes influence longevity? Is it possible to extend youthfulness by means of genetic manipulation? What does the aging of a yeast cell have in common with the aging of a human being or a mouse? Dr. Guarente analyzes these tantalizing questions and others in this episode.
Hosts: Marc Pelletier and Leo Laporte
Guest: Dr. Leonard P. Guarente
Thanks to CacheFly for providing the bandwidth for this podcast.
2006-07-2142 min