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Ground TruthsGround TruthsBob Bordone and Joel Salinas: How to Deal With ConflictIn our divided world we face or avoid conflicts on a frequent basis. I turned to Bob Bordone and Joel Salinas to find out the best strategies to deal with these, including having them take on a mock conflict between each other on the merits of Covid research.Audio fileYou can also find this on Spotify and Apple podcasts with Ground Truths.The video is also posted on YouTubeTranscript with Audio LinksEric Topol (00:06):Well, hello. It's Eric Topol with Ground Truths, and...2025-05-0529 minSean Carroll\'s Mindscape: Science, Society, Philosophy, Culture, Arts, and IdeasSean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and IdeasEric Topol on the Changing Face of Medicine and AgingMedical science is advancing at an astonishing rate. Today we talk with leading expert Eric Topol about two aspects of this story. First, the use of artificial intelligence in medicine, especially in diagnostics. This is an area that is a perfect match between an important question and the capabilities of machine learning, to the point where AI can out-perform human doctors. And second, our understanding of aging and what to do about it. Eric even gives some actionable advice on how to live more healthily into our golden years.Blog post with transcript: https://www.preposterousuniverse.com...2025-05-051h 12Infectious IDeasInfectious IDeasTechnology Enhancing Humanity with Eric Topol, MDSend us a textJoin Marla Dalton, PE, CAE, and William Schaffner, MD, for a fascinating conversation with cardiologist and renowned biomedical researcher Eric Topol, MD, on the revolutionary impact of artificial intelligence (AI) in medicine and healthcare. Topol shares how AI can help strengthen the patient-doctor relationship, enhance diagnostics, and reduce medical errors.Show notesA practicing cardiologist, Topol is chair and professor of Translational Medicine at Scripps Research. One of the most cited researchers in medicine, he has published several bestselling books on the future of medicine, including a...2025-04-0222 minGround TruthsGround TruthsSteve Quake and Charlotte Bunne: The Holy Grail of Biology“Eventually, my dream would be to simulate a virtual cell.”—Demis HassabisThe aspiration to build the virtual cell is considered to be equivalent to a moonshot for digital biology. Recently, 42 leading life scientists published a paper in Cell on why this is so vital, and how it may ultimately be accomplished. This conversation is with 2 of the authors, Charlotte Bunne, now at EPFL and Steve Quake, a Professor at Stanford University, who heads up science at the Chan-Zuckerberg Initiative The audio (above) is available on iTunes and Spotify. The full video...2025-03-1843 minGround TruthsGround TruthsAnna Greka: Molecular Sleuthing for Rare DiseasesFunding for the NIH and US biomedical research is imperiled at a momentous time of progress. Exemplifying this is the work of Dr. Anna Greka, a leading physician-scientist at the Broad Institute who is devoted to unlocking the mysteries of rare diseases— that cumulatively affect 30 million Americans— and finding cures, science supported by the NIH.A clip from our conversationThe audio is available on iTunes and Spotify. The full video is linked here, at the top, and also can be found on YouTube.Transcript with audio and external linksEric Topo...2025-03-0948 minGround TruthsGround TruthsCarl Zimmer: Air-Borne and the Big Miss With CovidBefore getting into this new podcast, have you checked out the recent newsletter editions and podcasts of Ground Truths?—the first diagnostic immunome—a Covid nasal vaccine update—medical storytelling and uncertainty—why did doctors with A.I. get outperformed by A.I. alone?The audio is available on iTunes and Spotify. The full video is embedded here, at the top, and also can be found on YouTube.Transcript with links to Audio and External Links Eric Topol (0...2025-02-2853 minGround TruthsGround TruthsEmily Silverman: Storytelling, Uncertainty, and Humanity in MedicineBefore getting into this new podcast, have you checked out the recent newsletter editions of Ground Truths?—how are gut microbiome drives sugar cravings—the influence of sleep on brain waste clearance and aging—the new findings of microplastics in the brain—the surprise finding about doctors and A.I.In this podcast with Dr. Emily Silverman, an internist and founder of The Nocturnists, an award winning podcast and live show, we discuss what inspired her in medicine, what led to her disillusionment, the essentiality of storytelling, of recog...2025-02-0947 minGround TruthsGround TruthsLotte Bjerre Knudsen: The Scientist Who Drove GLP-1 Drugs For Obesity and Alzheimer'sThe Chief Scientific Advisor at Novo Nordisk, Lotte Bjerre Knudsen, was the key force who pushed hard to develop GLP-1 drugs for treating obesity and subsequently for Alzheimer’s. She was recently recognized by the 2024 Lasker Medical Research Award, and the 2024 AAAS Bhaumik Breakthrough of the Year Award. That recognition is richly deserved, since it is unclear if the GLP-1 drug path to obesity treatment, and all of the associated benefits, would have been seen at this time without her influence. That’s especially true given the mystery for why people with Type 2 diabetes (for which these drugs were used...2025-01-0447 minGround TruthsGround TruthsArdem Patapoutian: The Pervasive PIEZO ChannelsPiezo touch and pressure-sensing ion channels are showing up everywhere as the explanation for physiologic phenomena, both at the macro and micro levels. Ardem Patapoutian, my friend and colleague at Scripps Research, discovered these receptors back in 2010 and was awarded the Nobel Prize in 2021 for his work. As you’ll see/hear from our conversation, the field has exploded. And you’ll get to know Ardem, who is such a fun, charismatic, and down-to-earth person. He also recently got a unique tattoo (videos below) and I wonder (unlikely) if any other Nobel laureates have one related to their discovery?!2024-12-2939 minGround TruthsGround TruthsMark Cuban: A Master Disrupter for American HealthcareAmerican healthcare is well known for its extreme cost and worst outcomes among industrialized (such as the 38 OECD member) countries, and beyond that to be remarkably opaque. The high cost of prescription drugs contributes, and little has been done to change that except for the government passing the Affordable Insulin Now Act at the end of 2022, enacted in 2023. But in January 2022 Mark Cuban launched Cost Plus Drugs that has transformed how many Americans can get their prescriptions filled at a fraction of the prevailing prices, bypassing pharmacy benefit managers (PBMs) that control 80% of US prescriptions. That was just the...2024-12-2037 minGround TruthsGround TruthsKevin Hall: What Should We Eat?A leader for conducting rigorous randomized trials of humans along with animal models for understanding nutrition and metabolism, Dr. Kevin Hall is a Senior Investigator at the National Institutes of Health, and Section Chief of the Integrative Physiology Section, NIDDK. In this podcast, we reviewed his prolific body of research a recent publications. The timing of optimizing our diet and nutrition seems apropos, now that we’re in in the midst of the holiday season!Below is a video snippet of our conversation on his ultra-processed food randomized trial.Full videos of all Gr...2024-11-3047 minScience Changing LifeScience Changing LifeFutureproof: Eric Topol on revolutionizing pandemic preparednessIn the second part of our conversation with Dr. Eric Topol, we explore how examining the past is necessary to ensure we’re more prepared for our future. From universal vaccines and advanced antiviral therapies to cutting-edge digital tools like wearable biosensors and genomic surveillance, Dr. Topol shares actionable insights on harnessing technology and data to revolutionize pandemic preparedness. Listen in as we discuss the path to a safer, healthier future. // Episode transcript: https://www.scripps.edu/_files/images/2024_images/topol-pandemic-prep-transcript.pdf Twitter: https://twitter.com/EricTopol LinkedIn: https://www.linkedin.com/in/eric-topol-md-b83a7317/ Ground Truths podcast: erictopol.substack.co...2024-11-2610 minGround TruthsGround TruthsThe Glaucomfleckens: The Best in Medical ComedyBelow is a brief video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The current one is here. If you like the YouTube format, please subscribe! This one has embedded one of my favorite TikTok’s from Will. There are several links to others in the transcript. The audios are also available on Apple and Spotify.Transcript with links to both audio and videos, commencement addresses, NEJM article coverageEric Topol (00:06):Hi, it's Eric Topol from Ground Truths, and I've got an amazing couple wi...2024-11-1635 minGround TruthsGround TruthsRachael Bedard: A Geriatric Physician and Champion for Patients Without a VoiceAbove is a brief video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with links to audio and external citationsEric Topol (00:06):Well, hello it's Eric Topol with Ground Truths, and I'm really delighted to welcome Dr. Rachael Bedard, who is a physician geriatrician in New York City, and is actually much more multidimensional, if you will. She's a writer. We're going to go over some of her recent writings...2024-11-0243 minScience Changing LifeScience Changing LifeBeyond the hype: AI’s impact on medicine and science with Eric TopolArtificial intelligence is revolutionizing what we once thought impossible. But how can we distinguish genuine breakthroughs from mere hype? In this episode of Science Changing Life, we welcome Eric Topol, MD—renowned physician, scientist, and author. As executive vice president at Scripps Research and founder of the Scripps Research Translational Institute, Dr. Topol shares his thoughts on how AI is transforming science and medicine today and offers a glimpse into what the future may hold. His advice to listeners? 'Be open to change.' Twitter: https://twitter.com/EricTopol LinkedIn: https://www.linkedin.com/in/eric-topol-md-b83a7317/ Ground Truths podcast: er...2024-11-0140 minGround TruthsGround TruthsKaterina Akassoglou: Blood Clots, Brain Inflammation, and CovidSuperimposed on an impressive body of work on the blood-brain-barrier and immune system, Prof Akassoglou and her collaborators just published an elegant study in Nature that centered on the direct binding os the SARS-CoV-2 spike protein to fibrin with marked downstream pro-inflammatory effects. The findings and potential treatments have implications beyond Covid, Long Covid to other neurologic diseases.Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with links to audio and to relevant papers, graphics2024-10-1935 minGround TruthsGround TruthsPatrick Hsu: A Trailblazer in Digital BiologyWhen I think of digital biology, I think of Patrick Hsu—he’s the prototype, a rarified talent in both life and computer science, who recently led the team that discovered bridge RNAs, what may be considered CRISPR 3.0 for genome editing, and is building new generative A.I. models for life science. You might call them LLLMs-large language of life models. He is Co-Founder and a Core Investigator of the Arc Institute and Assistant Professor of Bioengineering and Deb Faculty Fellow at the University of California, Berkeley.Above is a brief snippet of our conversation. Full videos of all...2024-10-1347 minGround TruthsGround TruthsAI Snake Oil—A New Book by 2 Princeton University Computer ScientistsArvind Narayanan and Sayash Kapoor are well regarded computer scientists at Princeton University and have just published a book with a provocative title, AI Snake Oil. Here I’ve interviewed Sayash and challenged him on this dismal title, for which he provides solid examples of predictive AI’s failures. Then we get into the promise of generative AI.Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with links to audio and external links to key...2024-09-2439 minGround TruthsGround TruthsFrancis Collins: On Truth, Science, Faith and TrustFrancis Collins is a veritable national treasure. He directed the National Institutes of Health from 2009 to 2021. Prior to that he led the National Human Genetics Research Institute (NHGRI) from 1997-2009, during which the human genome was first sequenced. As a physician-scientist, he has made multiple seminal discoveries on the genetic underpinnings of cystic fibrosis, Huntington’s disease, neurofibromatosis, progeria, and others. This brief summary is barely scratching the surface oh his vast contributions to life science and medicine.A video clip from our conversation on hepatitis C. Full videos of all Ground Truths podcasts can be seen on...2024-09-1140 minGround TruthsGround TruthsJoseph Allen: The Pivotal Importance of Air Quality, Ventilation and Exposures (Such as "Forever Chemicals") For Our HealthProfessor Joseph Allen directs the Healthy Buildings Program at Harvard Chan School of Public Health. His expertise extends far beyond what makes buildings healthy. He has been a leading voice and advocate during the Covid pandemic for air quality and ventilation. He coined the term “Forever Chemicals” and has written extensively on this vital topic, no less other important exposures, which we covered In our wide-ranging conversation. You will see how remarkably articulate and passionate Prof Allen is about these issues, along with his optimism for solutions.A video snippet of our conversation: buildings as the 1st line...2024-09-051h 01Fixing Healthcare PodcastFixing Healthcare PodcastFHC #146: Dr. Eric Topol on how AI is changing healthcareIn the first episode of Fixing Healthcare’s 10th season, cohosts Dr. Robert Pearl and Jeremy Corr speak with Dr. Eric Topol, a healthcare visionary and global technology leader. This season focuses on the future of technology in healthcare, a topic close to Dr. Pearl’s heart. His newest book, ChatGPT, MD: How AI-Empowered Patients & Doctors Can Take Back Control of American Medicine, debuted as an Amazon top new release. All profits from the book go to Doctors Without Borders. Dr. Topol is a renowned cardiologist and founder of the Scripps Research Translational Institute. He has...2024-09-0341 minGround TruthsGround TruthsSteve Horvath: Our Epigenetic Age ClocksSteve Horvath made the seminal discovery of the—Horvath Clock— an epigenetic clock based on DNA methylation, which is now being used extensively in medical research and offered commercially for individuals (←we talk about that!). He was on the faculty at UCLA from 2000-2022 as a Professor of Human Genetics and Biostatistics, and now works on anti-aging research at Altos Labs.A perspective on the importance of epigenetic clocks this week’s Nature”This insight is crucial for deriving reliable biological markers of ageing in tissues or blood. Such a feat has been accomplished through the ingenious identifica...2024-08-2341 minGround TruthsGround TruthsPradeep Natarajan: Preventing Heart DiseasePradeep is a brilliant geneticist and Director of Preventive Cardiology, holds the Paul & Phyllis Fireman Endowed Chair in Vascular Medicine at Mass General Hospital and on faculty at Harvard Medical School and the Broad Institute. His prolific research has been illuminating for the field of improving our approach to reduce the risk of heart disease. That’s especially important because heart disease is the global (and US) #1 killer and is on the increase. We didn’t get into lifestyle factors here since there was so much ground to cover on new tests. drugs, and strategies.A video snip...2024-08-1457 minGround TruthsGround TruthsShane Crotty: A Landmark Study on Upper Airway Mucosal ImmunityA video snippet of our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Shane Crotty: A Landmark Study on Upper Airway Mucosal ImmunityTranscriptThis is the first time a Ground Truths podcast is being posted simultaneous with a new publication, this one in Nature, by Professor Shane Crotty and his colleagues at La Jolla Institute for Immunology. Shane is one of the leading immunologists and virologists in the country; he and his group pub...2024-07-3138 minGround TruthsGround TruthsFaisal Mahmood: A.I.'s Transformation of PathologyFull videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Thank you for reading Ground Truths. This post is public so feel free to share it.Transcript with audio and external linksEric Topol (00:05):Hello, it's Eric Topol with Ground Truths, and I am really thrilled to have with me Professor Faisal Mahmood, who is lighting it up in the field of pathology with AI. He is on the faculty at Harvard Medical...2024-07-2841 minGround TruthsGround TruthsEuan Ashley: Exercise may be the single most potent medical intervention ever knownRecently, a series of papers were published in Nature and Nature journals illuminating the physiologic effects of exercise from an NIH initiative called MoTrPAC. To understand the wealth of new findings, I spoke with Professor Euan Ashley, who, along with Matt Wheeler, heads up the bioinformatics center.Earlier this week, Stanford announced Euan Ashley will be the new Chair of the Department of Medicine. He has done groundbreaking work in human genomics, including rapid whole genome sequencing for critically ill patients and applying the technology for people with unknown diseases. A few years ago he published The...2024-07-0548 minGround TruthsGround TruthsChristopher Labos: Debunking Myths About What We Eat and DrinkA book that reads like a novel; it’s humorous, it’s a love story. Dr. Christopher Labos, an imaginative cardiologist and epidemiologist at McGill University, takes us through multiple longstanding misconceptions about different foods and drinks, and along the way provides outstanding educational value.Video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with external links and links to the audio recordingEric Topol (00:07):He...2024-06-2645 minGround TruthsGround TruthsCharlie Swanton: A Master Class on CancerThe most enthralling conversation I’ve ever had with anyone on cancer. It’s with Charlie Swanton who is a senior group leader at the Francis Crick Institute, the Royal Society Napier Professor in Cancer and medical oncologist at University College London, co-director of Cancer Research UK.Video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with audio links and many external linksEric Topol (00:07):Well, hell...2024-06-1455 minGround TruthsGround TruthsTom Cech: RNA Takes Center StageIn this podcast, Thomas Czech, Distinguished Professor at the University of Colorado, Boulder, with a lineage of remarkable contributions on RNA, ribozyme, and telomeres, discuss why RNA is so incredibly versatile.Video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with links to the audio and external linksEric Topol (00:07):Well, hello, this is Eric Topol from Ground Truths, and it's really a delight for me to welcome Tom Cech...2024-06-0549 minGround TruthsGround TruthsVenki Ramakrishnan: The New Science of AgingProfessor Venki Ramakrishnan, a Nobel laureate for his work on unraveling the structure of function of the ribosome, has written a new book WHY WE DIE which is outstanding. Among many posts and recognitions for his extraordinary work in molecular biology, Venki has been President of the Royal Society, knighted in 2012, and was made a Member of the Order of Merit in 2022. He is a group leader at the MRC Laboratory of Molecular Biology research institute in Cambridge, UK.A brief video snippet of our conversation below. Full videos of all Ground Truths podcasts can...2024-05-2849 minGround TruthsGround TruthsSvetlana Blitshteyn: On the Front Line With Long Covid and POTSAfter finishing her training in neurology at Mayo Clinic, Dr. Svetlana Blitshteyn started a Dysautonomia Clinic in 2009. Little did she know what was in store many years later when Covid hit!Ground Truths podcasts are on Apple and Spotify. The video interviews are on YouTubeTranscript with audio and external linksEric Topol (00:07):Well, hello, it's Eric Topol from Ground Truths, and I have with me a really great authority on dysautonomia and POTS. We will get into what that is for those who aren't following this closely. And...2024-05-2053 minGround TruthsGround TruthsKate Crawford: A Leading Scholar and Conscience for A.I.“We haven't invested this much money into an infrastructure like this really until you go back to the pyramids”—Kate CrawfordTranscript with links to audio and external links. Ground Truths podcasts are on Apple and Spotify. The video interviews are on YouTube Eric Topol (00:06):Well, hello, this is Eric Topol with Ground Truths, and I'm really delighted today to welcome Kate Crawford, who we're very lucky to have as an Australian here in the United States. And she's multidimensional, as I've learned, not just a scholar of AI, all the dimens...2024-05-1351 minGround TruthsGround TruthsAkiko Iwasaki: The Immunology of Covid and the FutureIf there’s one person you’d want to talk to about immunology, the immune system and Covid, holes in our knowledge base about the complex immune system, and where the field is headed, it would be Professor Iwasaki. And add to that the topic of Women in Science. Here’s our wide-ranging conversation.A snippet of the video, Full length Ground Truths videos are posted here and you can subscribe. Ground Truths is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid s...2024-05-0441 minGround TruthsGround TruthsAviv Regev: The Revolution in Digital Biology“Where do I think the next amazing revolution is going to come? … There’s no question that digital biology is going to be it. For the very first time in our history, in human history, biology has the opportunity to be engineering, not science.” —Jensen Huang, NVIDIA CEOAviv Regev is one of the leading life scientists of our time. In this conversation, we cover the ongoing revolution in digital biology that has been enabled by new deep knowledge on cells, proteins and genes, and the use of generative A.I .Transcript...2024-04-2936 minGround TruthsGround TruthsJennifer Doudna: The Exciting Future of Genome EditingProfessor Doudna was awarded the 2020 Nobel Prize in Chemistry with Professor Emmanuelle Charpentier for their pioneering work in CRISPR genome editing. The first genome editing therapy (Casgevy) was just FDA approved, only a decade after the CRISPR-Cas9 editing system discovery. But It’s just the beginning of a much bigger impact story for medicine and life science.Ground Truths podcasts are now on Apple and Spotify. And if you prefer videos, they are posted on YouTubeTranscript with links to audio and relevant external linksEric Topol (00:06):Th...2024-04-1431 minGround TruthsGround TruthsDaniel Drucker: Illuminating the GLP-1 Drug's Break OutNote: This podcast is a companion to the Ground Truths newsletter “A Big Week for GLP-1 Drugs”Eric Topol (00:06):It is Eric Topol with Ground Truths, and with me today is Dr. Daniel Drucker from the University of Toronto, who is one of the leading endocrinologists in the world, and he along with Joel Habener and Jens Juul Holst from the University of Copenhagen and Denmark, have been credited with numerous prizes of their discovery work of glucagon-like peptide-1 (GLP-1) as we get to know these family of drugs and he's a true pioneer. He's been...2024-04-0636 minGround TruthsGround TruthsSid Mukherjee: On A.I., Longevity and Being A Digital HumanSiddhartha Mukherjee is a Professor at Columbia University, oncologist, and extraordinary author of Emperor of All Maladies (which was awarded a Pulitzer Prize), The Gene, and The Song of the Cell, along with outstanding pieces in the New Yorker. He is one of the top thought leaders in medicine of our era. “I have begun to imagine, think about what it would be to be a digital human..”—Sid MukherjeeEric Topol (00:06):Well, hello, this is Eric Topol with Ground Truths, and I am delighted to have my friend Sid Mu...2024-03-2947 minGround TruthsGround TruthsHolden Thorp: Straight Talk from the Editor-in-Chief of the Science family of journalsThere was so much to talk about—this is the longest Ground Truths podcast yet. Hope you’ll find it as thought-provoking as I did!Transcript, with audio and external links, edited by Jessica Nguyen, Producer for Ground TruthsVideo and audio tech support by Sinjun Balabanoff, Scripps ResearchEric Topol (00:00:05):This is Eric Topol from Ground Truths, and I am delighted to have with me Holden Thorp, who is the Editor-in-Chief of the Science journals. We're going to talk about Science, not just the magazine journal, but also scie...2024-03-171h 00Ground TruthsGround TruthsDaphne Koller: The Convergence of A.I. and Digital BiologyTranscript Eric Topol (00:06):Well, hello, this is Eric Topol with Ground Truths and I am absolutely thrilled to welcome Daphne Koller, the founder and CEO of insitro, and a person who I've been wanting to meet for some time. Finally, we converged so welcome, Daphne.Daphne Koller (00:21):Thank you Eric. And it's a pleasure to finally meet you as well.Eric Topol (00:24):Yeah, I mean you have been rocking everybody over the years with elected to the National Academy of Engineering and Science and right at the...2024-03-1035 minGround TruthsGround TruthsColeen Murphy: The Science of Aging and Longevity“A few years ago, I might have chuckled at the naiveté of this question, but now it's not so crazy to think that we will be able to take some sort of medicine to extend our healthy lifespans in the foreseeable future.”—Coleen MurphyTranscript with external linksEric Topol (00:06):Hello, this is Eric Topol from Ground Truths, and I'm just so delighted to have with me Professor Coleen Murphy, who has written this exceptional book, How We Age: The Science of Longevity. It is a phenomenal book an...2024-03-0344 minGround TruthsGround TruthsMichelle Monje: The Brain in Long Covid and CancerTranscript with audio and relevant external links, recorded on 6 Feb 2024Eric Topol (00:05):Hello, this is Eric Topol with Ground Truths, and I have a remarkable guest with me today, Professor Michelle Monje, who is from Stanford, a physician-scientist there and is really a leader in neuro-oncology, the big field of cancer neuroscience, neuroinflammation, and she has just been rocking it recently with major papers on these fields, no less her work that's been on a particular cancer, brain cancer in kids that we'll talk about. I just want to give you...2024-02-2543 minGround TruthsGround TruthsJim Collins: Discovery of the First New Structural Class of Antibiotics in Decades, Using A.I.Jim Collins is one of the leading biomedical engineers in the world. He’s been elected to all 3 National Academies (Engineering, Science, and Medicine) and is one of the founders of the field of synthetic biology. In this conversation, we reviewed the seminal discoveries that he and his colleagues are making at the Antibiotics-AI Project at MIT.Recorded 5 February 2024, transcript below with audio links and external links to recent publicationsEric Topol (00:05):Hello, it's Eric Topol with Ground Truths, and I have got an extraordinary guest with me today, Jim Collins, who's the Te...2024-02-1328 minGround TruthsGround TruthsKatalin Karikó: The unimaginable, obstacle-laden, multi-decade journey to discover the mRNA platform and win the 2023 Nobel Prize “The history of science, it turns out, is filled with stories of very smart people laughing at good ideas.”—Katalin Karikó Ground Truths podcasts are now available on Apple and Spotify!The list of obstacles that Kati Karikó faced to become a scientist, to make any meaningful discovery, to prevail over certain scientists and administrators who oppressed her, unable to obtain grants, her seminal paper rejected by all of the top-tier journals, demoted and dismissed, but ultimately to be awarded the 2023 Nobel Prize with Drew Weissman, is a story for the...2024-02-0354 minGround TruthsGround TruthsJonathan Howard, author of We Want Them InfectedJonathan Howard is a neurologist and psychiatrist who practices at NYU-Bellevue and posts frequently on Science Based Medicine.Transcript, unedited, with links to audioEric Topol (00:05):Well, hello, Eric Topol with Ground Truths and I'm really pleased to have the chance to talk with Jonathan Howard today, who is a neurologist and psychiatrist at NYU at Bellevue and has written quite an amazing book published a few months months ago called We Want Them Infected, so welcome Jonathan.Jonathan Howard (00:27):Hey, thanks so much for...2024-01-2543 minGround TruthsGround TruthsLiv Boeree: On Competition, Moloch Traps, and the A.I. Arms RaceA snippet of our conversation belowTranscript of our conversation 8 January 2023, edited for accuracy, with external linksEric TopolIt’s a pleasure for me to have Liv Boeree as our Ground Truths podcast guest today. I met her at the TED meeting in October dedicated to AI. I think she's one of the most interesting people I’ve met in years and the first time I've ever interviewed a professional poker player who has won world championships and we're going to go through that whole story, so welcome Liv...2024-01-1336 minGround TruthsGround TruthsTony Wyss-Coray: The Science of AgingThe science to advance our understanding of the aging process—and to potentially slow it down—has made important strides. One of the leading scientists responsible for this work is Professor Tony Wyss-Coray, whose work has particularly focused on brain aging but has implications for all organs. I believe his December 2023 Nature paper on blood proteins that can track aging for 11 of our organs is one of the most important aging reports yet.Here is the audio and transcript of our conversation, recorded 20 December 2023, with a few relevant external links.This is the last Ground Trut...2023-12-2632 minGround TruthsGround TruthsDavid Liu: A Master Class on the Future of Genome EditingDavid Liu is an gifted molecular biologist and chemist who has pioneered major refinements in how we are and will be doing genome editing in the future, validating the methods in multiple experimental models, and establishing multiple companies to accelerate their progress.The interview that follows here highlights why those refinements beyond the CRISPR Cas9 nuclease (used for sickle cell disease) are vital, how we can achieve better delivery of editing packages into cells, ethical dilemmas, and a future of somatic (body) cell genome editing that is in some ways is up to our imagination, because of...2023-12-1047 minGround TruthsGround TruthsGeoffrey Hinton: Large Language Models in Medicine. They Understand and Have EmpathyThis is one of the most enthralling and fun interviews I’ve ever done (in 2 decades of doing them) and I hope that you’ll find it stimulating and provocative. If you did, please share with your network.And thanks for listening, reading, and subscribing to Ground Truths.Recorded 4 December 2023Transcript below with external links to relevant material along with links to the audioERIC TOPOL (00:00):This is for me a real delight to have the chance to have a conversation with Geoffrey Hinton. I followed his work...2023-12-0836 minGround TruthsGround TruthsAndrew Ng: On OpenAI's stormy times, AI regulation, education, and where we are headed for healthcare and beyond“A.I. is not the problem; it’s the solution.”—Andrew Ng at TED, 17 October 2023Recorded 21 November 2023Transcript with relevant links and links to audio fileEric Topol (00:00):Hello, it's Eric Topol with Ground Truths, and I'm really delighted to have with me Andrew Ng, who is a giant in AI who I've gotten to know over the years and have the highest regard. So Andrew, welcome.Andrew Ng (00:14): Hey, thanks Eric. It's always a pleasure to see you.Eric Topol (00:16):Yeah, we...2023-11-2132 minGround TruthsGround TruthsThe Science Behind Food and Dangers of Ultra-Processed, Artificial, Non-Food with Dr. Chris Van TullekenIf you care about what you eat, you won’t want to miss this conversation! Chris Van Tulleken is an infectious disease physician-scientist in the UK’s National Health Service who has written a deeply researched masterpiece book on food—ULTRA-PROCESSED PEOPLE. It’s not just about these synthetic and artificial UPF substances, that carry many health hazards, but also about our lifestyle and diet, challenging dogma about low carbs/glycemic index and the impact of exercise. Chris ate an 80% UPF diet for a month with extensive baseline and follow-up assessments including MRI brain scans. He has an ident...2023-10-2446 minGround TruthsGround TruthsPeter Attia: Our conversation about his hit book OUTLIVE, Medicine 3.0, promoting healthspan, GLP-1 drugs and moreIn July, I reviewed Peter’s Outlive book here in Ground Truths and hoped I’d be able to interview him about my concerns. Here’s that conversation, recorded October 16th. I hope you’ll find it informative and stimulating!The AI generated transcript (unedited) below with links to the audio recordingEric Topol (00:01):Peter, it's really great to see you. I haven't been chance to visit since early 2020, and you introduced me to Topo Chico as a great way to get carbonated water. Are you still into those?Pet...2023-10-1943 minGround TruthsGround TruthsOn Genome Editing With Fyodor Urnov, A PioneerRecorded 11 October 2023Beyond being a brilliant scientist, Fyodor is an extraordinary communicator as you will hear/see with his automotive metaphors to explain genome editing and gene therapy. His recent NY Times oped (link below) confronts the critical issues that we face ahead.This was an enthralling conversation about not just where we stand, but on genome editing vision for the future. I hope you enjoy it as much as I did.Transcript with key linksEric Topol (00:00):Well for me, this is really a special conversation...2023-10-1347 minTLC Sessions - Living with Long CovidTLC Sessions - Living with Long CovidEpisode 63: Eric Topol, M.D – Cardiologist and prolific Long Covid authorEric Topol must be one of the leading voices in Long Covid advocacy.  Cardiologist, scientist, author, editor-in-chief of Medscape, and founder of the Scripps Research Translational Institute, Topol has written about Long Covid in publications from The Lancet and Nature, to The Washington Post.  As a clinician a large proportion of his patients are now Long Covid sufferers and he spends a huge amount of his time pushing for advancements in Long Covid treatment and prevention.  In this week’s episode Dr. Topol guides us through his frustrations surrounding the lack of urgency with which the world is tr...2023-09-2053 minGround TruthsGround TruthsStraight Talk with Peter HotezDr. Peter Hotez is a veritable force. He has been the tip of the spear among physicians and scientists for taking on anti-science and has put himself and his family at serious risk.Along with Dr. Maria Bottazzi, he developed the Corbevax Covid vaccine —without a patent— that has already been given to over 10 million people, and was nominated for the Nobel Peace Prize. Here an uninhibited, casual and extended conversation about his career, tangling with the likes of RFK Jr, Joe Rogan, Tucker Carlson, Steve Bannon, and an organized, funded, anti-science mob, along with related topics.2023-09-1948 minGround TruthsGround TruthsZiyad Al-Aly: Illuminating Long CovidFew, if any, physician researchers have done more to understand the long-term impact of Covid than Dr. Ziyad Al-Aly, a professor, nephrologist, and epidemiologist along with his team at Washington University, St. Louis. Here is the transcript (with links to the audio) of our conversation that was recorded one 7 September 2023.Eric Topol (00:00):Welcome to Ground Truths, and this podcast is a special one for me. I get to meet professor Dr. Ziyad Ali for the first time, even though we've been communicating for years. So welcome, Ziyad.Ziyad Al-Aly (00:15):...2023-09-1141 minGround TruthsGround TruthsStraight talk with Magdalena Skipper, the Editor-in-Chief at NatureEric Topol (00:00):Hello, this is Eric Topol, and I'm thrilled to have a chance to have a conversation with Magdalena Skipper, who is the Editor-in-Chief of Nature. And a historic note. Back in 2018, she became the first woman editor of Nature in its 149 years, and only the eighth editor of all times. Having taken over for Philip Campbell, who had been previously the editor for 22 years, we're going to ask her if she's going to do 22 or more years, but we're going to have a fun conversation because there's so much...2023-08-1945 minGround TruthsGround TruthsJohn Halamka: How Mayo Clinic is Transforming Healthcare with A.I.Transcript Eric Topol (00:00):This is a real great opportunity to speak to one of the most impressive medical informaticists and leaders in AI in the United States and worldwide. Dr. John Halamka, just by way of background, John, his baccalaureate in Stanford was at U C S F/Berkeley for combined MD PhD trained in emergency medicine at U C L A. He went on to Harvard where he, for 20 years was the Chief Information Officer at Beth Israel Deaconess. And then in 2020 he joined Mayo Clinic to head its platform to help...2023-08-1133 minGround TruthsGround TruthsMelanie Mitchell: Straight Talk on A.I. Large Language ModelsTranscript with LinksEric Topol (00:00):This is Eric Topol, and I'm so excited to have the chance to speak to Melanie Mitchell. Melanie is the Davis Professor of Complexity at the Santa Fe Institute in New Mexico. And I look to her as one of the real, not just leaders, but one with balance and thoughtfulness in the high velocity AI world of large language models that we live in. And just by way of introduction, the way I got to first meet Professor Mitchell was through her book, Artificial Intelligence, A Guide...2023-08-0439 minGround TruthsGround TruthsAl Gore: The Intersection of A.I. and Climate ChangeTranscript with some hyperlinksEric Topol (00:00):Hello, Eric Topol here. And what a privilege to have as my guest Al Gore, as we discuss things that are considered existential threats. And that includes not just climate change but also recently the concern about A.I. No one has done more on the planet to bring to the fore the concerns about climate change. And many people think that the 2006 film, An Inconvenient Truth, was the beginning, but it goes way back into the 1980s. So, Al it's really great to have you put...2023-06-2134 minThe Heart of Healthcare | A Digital Health PodcastThe Heart of Healthcare | A Digital Health PodcastSniffing Out Hope vs Hype in Digital Health | Digital Health Godfather Dr. Eric TopolIn this episode, we sit down with Dr. Eric Topol, the godfather of digital health, to explore the progress and barriers to innovation in healthcare, the potential of AI in transforming the industry, and the challenges faced by startups and big tech companies. Dr. Topol shares his insights on open-source healthcare, evaluating new innovations, and the importance of algorithmic fairness. Tune in to gain deep insights into the future of medicine and the power of technology in reshaping healthcare.Follow Dr. Eric Topol on TwitterFollow Halle Tecco on Twitter2023-06-1241 minGround TruthsGround TruthsHannah Davis: A 360° on Long CovidTRANSCRIPTEric Topol (00:00):Hello, this is Eric Topol, and it's really a delight for me to welcome Hannah Davis who was the primary author of our recent review on Long Covid and is a co-founder of the Patient-Led Research Collaborative. And we're going to get into some really important topics about citizen science, Long Covid and related matters. So, Hannah, welcome.Hannah Davis (00:27):Thank you so much for having me.Eric Topol (00:29):Well, Hannah, before we get into it I thought because you had a very interesting...2023-06-0642 minGround TruthsGround TruthsPeter Lee and the Impact of GPT-4 + Large Language AI Models in MedicineLink to the book: The AI Revolution in MedicineLink to my review of the bookLink to the Sparks of Artificial General Intelligence preprint we discussedLink to Peter’s paper on GPT-4 in NEJMTranscript (with a few highlights in bold of many parts that could be bolded!)Eric Topol (00:00):Hello, I'm Eric Topol, and I'm really delighted to have with me Peter Lee, who's the director of Microsoft Research and who is the author, along with a couple of colleagues fo...2023-05-2243 minGround TruthsGround TruthsStraight talk with Michael OsterholmTranscript Eric (00:00):Okay. Hello, this is Eric Topol and this is a rare privilege for me to interview my favorite epidemiologist, Dr. Michael Osterholm. He is the Regents Professor of the University of Minnesota. He's director of CIDRAP, which is certainly one of the leading entities around the world for public health. And, we've been friends for the last few years, which we'll we'll talk about. So, welcome Michael. Such a great privilege to have you today.Michael (00:31):Well, thank you, the honor, really is mine. As I have shared with...2023-05-0534 minIn the Bubble with Andy SlavittIn the Bubble with Andy SlavittWho Should Get a Second Booster? (with Dr. Eric Topol)New guidelines from the CDC have people wondering: Just who should get a second COVID booster? In the Bubble favorite Dr. Eric Topol returns to break down who should get boosted, who should get a second booster, and who can wait a bit. They also discuss Eric’s thoughts on where we are in the fight against COVID and what the next frontier of vaccines will look like. Plus, Andy and Eric reflect on Dr. Ashish Jha’s time as the head of the COVID White House task force and look back at what he was able to accomplish. 2023-05-0341 minDigital Health & WearablesDigital Health & WearablesTaking the pulse on Digital Health with Dr. Eric Topol and João Bocas João Bocas - The #Wearables Expert ™ Interviews Dr. Eric Topol, World renowned Cardiologist, Digital Health Influencer, Physician - Scientist and Author This is a very special episode that marks the 2 year anniversary of the YouTube Channel. The Topic is: Taking the pulse on Digital Health We've discussed and touched upon : - Digital Health and the state of the industry right now - How the pandemic impacted digital health - Detect Health Study ( using wearables ) Recommended books by Dr. Eric Tol : 1) The Creative Destruction of Medicine 2) The Patient will see you now 3) Deep Medicine BUY HERE - https://drerictopol.com...2023-03-2118 minZOE Science & NutritionZOE Science & NutritionThe future is here: AI and personalized healthcare with Eric TopolIf you were to ask Siri, Alexa, or ChatGPT for medical advice right now, that would be a terrible idea. But with recent developments in technology, this looks set to change. AI has become more intelligent, wearable devices - more accurate, and personalized medicine - increasingly mainstream.But is any of this safe? Should we really trust machines with our health? And will any of this actually happen?In today’s episode, Jonathan speaks to Eric Topol to explore how artificial intelligence may transform your next trip to the doctor. Eric Topol is...2023-03-0246 minFixing Healthcare PodcastFixing Healthcare PodcastFHC #81: Eric Topol on the future of AI, medical education and leadershipDr. Eric Topol, now a three-time returning guest on the Fixing Healthcare podcast, discusses 21st-century lessons in leadership. Topol is the director of the Scripps Research Institute and a professor of molecular medicine. He has published more than 1,200 peer-reviewed articles and serves as the editor-in-chief of Medscape. He has authored three bestselling books including his most recent, “Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again.” In this episode, Topol talks about the future of medical leadership and the role of AI (including ChatGPT), genomics research and genome editing, medical education and the retail/phar...2023-02-0849 minHealth & VeritasHealth & VeritasDr. Eric Topol: Pushing Medicine into the FutureHowie and Harlan are joined by Dr. Eric Topol, a physician and writer who is widely recognized both as a leading researcher and a public voice on medicine and health. They discuss his career turn toward genomics and digital health, and the fight against misinformation on Twitter.  Links: “Adding Salt to Foods and Risk of Cardiovascular Disease” Eric Topol: Ground Truths Eric Topol: The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care (2011) Eric Topol: The Patient Will See You Now: The Future of Medicine Is in...2022-12-0134 minNight ScienceNight Science24 | Eric Topol on thinking big about AI in medicineEric Topol is a cardiologist, scientist, and author. Many twitter users will know Eric from his voice-of-reason tweets related to the covid pandemic. While Eric’s exceptionally broad scientific work includes genetics and clinical trials, his main focus is on the ways in which artificial intelligence may change medicine as we know it. Creativity in this field, Eric explains, lies in exploring applications of AI that no one thought possible before, such as predicting the risk of heart disease from an image of the retina. In our conversation, Eric encourages any scientist to...2022-11-2139 minIn the Bubble with Andy SlavittIn the Bubble with Andy SlavittHow Nasal Vaccines Could Transform the Pandemic (with Eric Topol)COVID-19 vaccines are no longer blocking infections like they used to. Nasal vaccines could help patch up the holes where the new variants like BA.5 are getting in. Andy talks to physician and scientist Eric Topol about the promising trials underway, when we could see a nasal vaccine hit the market, and why it could transform our pandemic response by providing mucosal immunity. Keep up with Andy on Twitter @ASlavitt. Follow Eric Topol on Twitter @EricTopol. Joining Lemonada Premium  is a great way to support our show and get bonus content. Subscribe today a...2022-08-0141 minIn the Bubble with Andy SlavittIn the Bubble with Andy SlavittWhy Do Some People Keep Getting COVID? (with Eric Topol)With BA.5 infecting and reinfecting people around the world, Andy wants to know why some people keep getting COVID while others seemingly never contract the virus. Apart from your daily safety decisions, it may have to do with your genetics, gut microbiome, and defense proteins called interferons. Physician and scientist Eric Topol breaks down these theories for Andy as they discuss BA.5’s severity compared to earlier versions of Omicron and what variant could come next. Keep up with Andy on Twitter @ASlavitt. Follow Eric Topol on Twitter @EricTopol. Joining Lemonada Premium is a...2022-07-2734 minFixing Healthcare PodcastFixing Healthcare PodcastFHC #51: Eric Topol on breaking the rules and putting patients in chargeOne hard part about interviewing Dr. Eric Topol is knowing where to begin. Topol wears a seemingly infinite array of hats: He is the director of Scripps Research Translational Institute. He’s a professor of molecular medicine. He’s an expert on artificial intelligence, Covid-19, genome editing and precision medicine. He’s a bestselling author, the editor of the popular healthcare publication MedScape, and one of the most followed physicians on Twitter. Thus, another hard part about interview Eric Topol is knowing you’ll always have far more questions than time to ask them. For this int...2022-05-0931 minThe Psychology PodcastThe Psychology PodcastEric Topol || Public Service Announcement: Separating Facts from Myths in the PandemicIt's important to recognize that when we're dealing with a very new or rapidly changing phenomenon, like we have been with the pandemic, even the "scientific consensus" can easily be wrong because there's not been much time for the rigorous replicability studies to be conducted or even sometimes to accurately measure the proper effect sizes. However, I also believe it's important that we don't create a false equivalency between very fringe ideas that are unsupported by the current evidence base and a scientific consensus that is grounded in rigorous methodology. This is why I sought ou...2022-02-1031 minThe Gary Bisbee ShowThe Gary Bisbee Show29: COVID, AI, and the Future of Medicine with Eric Topol, M.D., Founder & Director, Scripps Research Translational InstituteMeet Dr. Eric Topol:Dr. Eric Topol is a cardiologist, scientist, and author. He is the Founder and Director of Scripps Research Translational Institute, and the Executive Vice-President of Scripps Research. He has published over 1200 peer-reviewed articles and is one of the top 10 most cited researchers in medicine. In 2016, Dr. Topol received a $207 million grant from the NIH to lead a portion of All of Us, part of the Precision Medicine Initiative. He is the author of three books on healthcare and is known for his commentary on patient-centered care and artificial intelligence. Key Insights:2021-09-3045 minInto the Impossible With Brian KeatingInto the Impossible With Brian KeatingEric Topol: AI Doctors, Medicine's Future, and The Delta Variant#AI #FutureofMedicine #EricTopolDr. Eric Topol M.D. is a Physician-Scientist, Author, Editor and is The Gary & Mary West Endowed Chair of Innovative Medicine, and the Executive VP, Scripps Research.We discussed the meaning of life, ways for Artificial Intelligence to improve patient outcomes…and concomitantly, benefit physicians too. We explored the ethical imperatives incumbent on doctors— is it ok to exaggerate medical benefits/risks to incentivize greater patient participation. We closed with his concerns about Elon Musk's long-term space travel from a medical perspective, including his thoughts on the Kelly twin astronaut study.S...2021-08-1058 minIn the Bubble with Andy SlavittIn the Bubble with Andy SlavittDelta: What to Worry About and What Not to (with Eric Topol)Andy calls up physician, scientist, and author Eric Topol for a can't-miss, in-depth conversation on the Delta variant. Andy and Eric cover why it's taking over, what vaccinated people should be thinking, and whether there's more variants like it to come. They also discuss the latest vaccine data out of Israel and why the FDA hasn’t fully approved the COVID vaccines yet. Plus, a sneak peek at Andy’s interview with Pfizer CEO Dr. Albert Bourla.   Keep up with Andy on Twitter @ASlavitt and Instagram @andyslavitt. Check out In the Bubble’s Twitter account @inthebu...2021-07-261h 02Science Changing LifeScience Changing LifeEpisode 24- Eric Topol & Andrew Ward: How Spike Protein Discoveries Drove Coronavirus Vaccine DesignAnother special edition featuring an extended conversation between Dr. Eric Topol, Director of the Scripps Research Translational Institute, and Professor Andrew Ward in the Department of Integrative Structural and Computational Biology at Scripps Research. Listen as they talk about structural biology as a gamechanger in coronavirus research, what makes the SARS-CoV-2 spike protein crucial for vaccine design, and what the latest coronavirus mutations mean for the pandemic. Show notes: The Ward Lab: https://ward.scripps.edu/ Dr. Eric Topol’s bio: www.scripps.edu/faculty/topol/ Inside the Lab That Invented the COVID-19 Vaccine: https://www.youtube.com/watch?v=-9...2020-12-2335 minFixing Healthcare PodcastFixing Healthcare PodcastEpisode 28: Eric Topol sees the future of medicine as ‘man plus machine’American doctors have gained a reputation for resisting the types of technologies that could make healthcare more convenient and cost-effective. But have physicians really earned their technophobic stigma? This episode of Fixing Healthcare features Eric Topol, a returning guest who’s back to discuss the tricky intersection between physician culture and healthcare technology. Topol is a cardiologist, geneticist, researcher and pioneer in the field of digital care. He has published three bestselling books on the future of medicine and serves as editor-in-chief of the popular healthcare news site Medscape. As founder and director of Scripps Re...2020-12-1454 minBig Picture MedicineBig Picture Medicine#040 Leadership Shorts: Dr Eric TopolDo you need to be a d**k to be a good leader? Here's what Dr Eric Topol said... Dr Eric Topol is in the top 10 most cited doctors in the history of Medicine. He is a cardiologist, geneticist and digital medicine expert — and was commissioned by the UK’s Health Secretary to write a report to prepare the NHS for the digital future: The Topol Review. Dr Topol has three best selling books on the future of Medicine: the Creative Destruction of Medicine, The Patient Will See you Now and Deep Medicine: How Artificial Inte...2020-12-1002 minIn the Bubble with Andy SlavittIn the Bubble with Andy SlavittA 90% Effective Vaccine! (with Eric Topol)Could this be a light at the end of the tunnel? Andy evaluates the remarkable news that Pfizer's COVID-19 vaccine proved more than 90% effective with physician, scientist and author Eric Topol. How excited should you be? What do we know and what don’t we know? What’s the timing and what comes next? Plus, a look at President-Elect Biden's COVID-19 task force. Keep up with Andy on Twitter @ASlavitt and Instagram @andyslavitt. Follow Eric Topol on Twitter @EricTopol.  In the Bubble is supported in part by listeners like you. Become a member, get e...2020-11-1146 minRaise the LineRaise the LineUsing Technology to Enhance the Humanity in Medicine - Dr. Eric Topol, Executive VP of Scripps Research“It seems counterintuitive, but I believe we can use technology to enhance the humanity in medicine and get back to the deep connection with patients we used to have,” says Dr. Eric Topol, one of the most cited researchers and influential thinkers in the field. In a series of bestselling books on the future of medicine, Topol laid out that digitization of health information would lead to democratization of data and patient empowerment, and that applying machine learning and other technologies in the right ways could actually create room to enhance the level of humanity in medicine – something he feels has be...2020-10-2723 minScience Changing LifeScience Changing LifeEpisode 20 – Eric Topol & Dennis Burton: Antibodies, Vaccines and the Current State of COVID-19Today’s special edition features an extended conversation between Dr. Eric Topol, Director of the Scripps Research Translational Institute, and Professor Dennis Burton, Chair of the Department of Immunology and Microbiology at Scripps Research. Listen as they talk about antibody cocktail treatments, the mystery of “longhaul” COVID-19 symptoms and how close we are to developing a coronavirus vaccine. Transcript of today's episode https://www.scripps.edu/covid-19/videos/topol-burton/index.html Dr. Eric Topol’s bio https://www.scripps.edu/faculty/topol/ Prof. Dennis Burton’s bio https://www.scripps.edu/faculty/burton/ Efficacy of convalescent plasma https://www.sandiegouniontribune.com/busine...2020-09-0145 minBig Picture MedicineBig Picture Medicine#020 Deep Medicine 🚀 — Dr Eric TopolWhat would you be working on if you were a medical student today? Dr Eric Topol is in the top 10 most cited doctors in the history of Medicine. He is a cardiologist, geneticist and digital medicine expert — and was commissioned by the UK’s Health Secretary to write a report to prepare the NHS for the digital future: The Topol Review. Dr Topol has three best selling books on the future of Medicine: the Creative Destruction of Medicine, The Patient Will See you Now and Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. This...2020-07-2630 minThe Military Medicine PodcastThe Military Medicine PodcastEric Topol - Deep Military MedicineIn the 14th Episode of the Military Medicine Podcast, we interview Dr Eric Topol. A Cardiologist by background, Dr Topol is perhaps best known for his work on the intersection between healthcare and technology - publishing 3 best-selling books on the topic, and also authoring the NHS "Topol review" on digitisation, last year. We hope you enjoy this episode, and please do leave us a 5* review and share with a friend if so!2020-05-1100 minCreating a New HealthcareCreating a New HealthcareEpisode #69: Humanizing Healthcare with Artificial Intelligence – with Dr. Eric TopolA lot has been said about the application of Artificial Intelligence (AI) to healthcare. These discussions typically center on AI’s ability to improve diagnostic accuracy, reduce medical errors, lower healthcare costs, enhance productivity, and even replace providers. We will cover some of that ground as well, but our guest’s perspective takes the discussion far beyond those more familiar topics. His firm belief is that the major impact AI could have on healthcare delivery would be to restore “the human bond, the human touch, and the human factor that has been lost.” This is a unique opinion...2019-09-1235 minThe All Turtles PodcastThe All Turtles PodcastAI in medicine with Dr. Eric TopolAI has already made its way into in the medical field, and today, Dr. Eric Topol gives us a sense of the many ways in which medical professionals are already taking advantage of this technology. Dr. Topol is a cardiologist and the author of Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. He acknowledges AI’s security risks, but is optimistic for the future of health that AI is helping to usher in. Show notes Conversation with Dr. Topol (0:50) Dr. Eric Topol is a cardiologist. Dr. Topol is th...2019-09-1127 minHeart podcastHeart podcastDeep Medicine with Eric Topol, author of the Topol NHS reviewIn this episode of the Heart podcast, Digital Media Editor, Dr James Rudd, is joined by Dr Eric Topol, founder and director of the Scripps Research Translational Institute. They discuss the impact that AI will have in medicine and how this will affect us all. Relevant links related to this podcast: About Dr Topol - https://drerictopol.com/about/ Nature Medicine AI review - https://www.nature.com/articles/s41591-018-0300-7 Twitter - https://twitter.com/EricTopol?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor Book - https://drerictopol.com/book/deep-medicine/ NHS Topol review - https://www...2019-08-1525 minBMJ talk medicineBMJ talk medicineDeep Medicine with Eric Topol, author of the Topol NHS reviewIn this episode of the Heart podcast, Digital Media Editor, Dr James Rudd, is joined by Dr Eric Topol, founder and director of the Scripps Research Translational Institute. They discuss the impact that AI will have in medicine and how this will affect us all. Relevant links related to this podcast: About Dr Topol - https://drerictopol.com/about/ Nature Medicine AI review - https://www.nature.com/articles/s41591-018-0300-7 Twitter - https://twitter.com/EricTopol?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor Book - https://drerictopol.com/book/deep-medicine/ NHS Topol review - https://www...2019-08-1525 minHeart podcastHeart podcastDeep Medicine with Eric Topol, author of the Topol NHS reviewIn this episode of the Heart podcast, Digital Media Editor, Dr James Rudd, is joined by Dr Eric Topol, founder and director of the Scripps Research Translational Institute. They discuss the impact that AI will have in medicine and how this will affect us all. Relevant links related to this podcast: About Dr Topol - https://drerictopol.com/about/ Nature Medicine AI review - https://www.nature.com/articles/s41591-018-0300-7 Twitter - https://twitter.com/EricTopol?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor Book - https://drerictopol.com/book/deep-medicine/ NHS Topol review - https...2019-08-0625 minHeart PodcastHeart PodcastDeep Medicine with Eric Topol, author of the Topol NHS reviewIn this episode of the Heart podcast, Digital Media Editor, Dr James Rudd, is joined by Dr Eric Topol, founder and director of the Scripps Research Translational Institute. They discuss the impact that AI will have in medicine and how this will affect us all. Relevant links related to this podcast: About Dr Topol - https://drerictopol.com/about/ Nature Medicine AI review - https://www.nature.com/articles/s41591-018-0300-7 Twitter - https://twitter.com/EricTopol?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor Book - https://drerictopol.com/book/deep-medicine/ NHS Topol review - https...2019-08-0625 minDataPointDataPointHow Artificial Intelligence actually makes medicine more human - A Deep Medicine conversation with Eric Topol, MD of Scripps ResearchToday's guest: Eric Topol, MD | Founder and Director, Scripps Research Translational InstituteGreg and Eric talk about the genesis of Scripps' remarkable efforts in genomics and digital health, the wealth of insight that's already available today due to a wealth of data & advanced "Deep Medicine" and talk about the future impact of Food as Medicine - e.g., "Deep Diet."Important Links:Deep Medicine site: https://drerictopol.com/book/deep-medicine/Eric Topol's site: https://drerictopol.com/Eric Topol's Twitter: https://twitter.com/erictopolEscaping the Scarcity Loop...2019-07-1633 minDataPointDataPointAn introduction to Deep Medicine & its author - Eric Topol of the Scripps Research Translational InstituteGreg sketches in background on how and why Dr Eric Topol has become such an important leader in creating a vision for the future of healthcare, establishing important context for Topol's upcoming DataPoint interview. He also shares some new statistics for measuring the impact of physicians in shaping the public dialog & delivers some surprising results.Deep Medicine site: https://drerictopol.com/book/deep-medicine/ Eric Topol's site: https://drerictopol.com/Eric Topol's Twitter: https://twitter.com/erictopolThe Scripps Institute Transitional Research site: https://www.scripps.edu/science-and-medicine/translational-institute/ 2019-07-1508 minEconTalkEconTalkEric Topol on Deep MedicineCardiologist and author Eric Topol talks about his book Deep Medicine with EconTalk host Russ Roberts. Topol argues that doctors spend too little face-to-face time with patients, and the use of artificial intelligence and machine learning is a chance to emphasize the human side of medicine and to expand the power of human connection in healing. Topol surveys the current landscape of the application of technology to health care showing where its promise has been overstated and where it is having the most impact. The conversation includes a discussion of the placebo effect and the importance of the human...2019-06-241h 08Mission DailyMission DailyHow A.I. Is Humanizing Healthcare with Dr. Eric TopolCan A.I. and machine learning make healthcare more humane, loving, and passionate? Dr. Eric Topol thinks so. Dr. Topol is a geneticist, medical researcher, and author of Deep Medicine. He has written over 1100 peer-reviewed articles and is one of the top most-cited medical researchers in the world. In this episode, Chad sits down with Dr. Topol to talk about how A.I. and machine learning are putting the patient experience back at the forefront of healthcare. Dr. Topol also explains why you don’t actually own your own medical data and what st...2019-04-1140 minScience Changing LifeScience Changing LifeEpisode 13 – Eric Topol: High Performance Medicine – How Technology Can Bring Back HumanityDr. Eric Topol is the Founder and Director of The Translational Institute at Scripps Research. Listen as we talk about bringing back empathy in medicine, smartphone ultrasounds and the best media for absorbing scientific information. Show notes: Translational Institute at Scripps Research https://www.scripps.edu/science-and-medicine/translational-institute/ Eric’s new book: Deep Medicine https://www.amazon.com/Deep-Medicine-Artificial-Intelligence-Healthcare/dp/1541644638 Current and future applications of technology in healthcare https://www.nature.com/articles/s41591-018-0300-7.pdf The Topol Review on the future of the NHS https://topol.hee.nhs.uk/ Eric’s 2016 Tedx Talk https://www.youtube.com/watc...2019-03-1222 minThe #HCBiz Show!The #HCBiz Show!Deep Medicine with Dr. Eric TopolThe way we practice medicine today is broken. We prioritize the business and treat the patient as nothing more than a cog in our great machine. According to today’s guest, ” we have an emotional breakdown, with disenchanted patients largely disconnected from burned-out, depressed doctors.” Dr. Eric Topol calls this epidemic “shallow medicine”. It’s driven by runaway healthcare costs and an insatiable drive for increased efficiency and profits, and unfortunately, is largely the way we deliver healthcare today. Because of this, Topol says, “patients exist in a world of insufficient data, insufficient time, insufficient context, and insufficient presence.” But, Dr. T...2019-03-1254 minFixing Healthcare PodcastFixing Healthcare PodcastEpisode 4: Dr. Eric Topol says ‘step one is providing healthcare to all citizens’Fixing Healthcare co-hosts Dr. Robert Pearl and Jeremy Corr thought they new a lot about their latest guest, Dr. Eric Topol. They’d both read his bestselling books and closely followed his groundbreaking work at Scripps Research. And then Dr. Topol opened up about his plan for fixing American healthcare. Each month, a new guest appears on the show to compete for the highly coveted (and totally fictitious) role of “Leader of American Healthcare.” The guest is given 10 minutes to present his plan for radically improving the U.S. medical system and Dr. Topol didn’t waste a second...2018-11-0757 minThe ShiftShapers PodcastThe ShiftShapers PodcastEp #83: Power To The Patients! – With Dr. Eric TopolThis week’s guest believes that the smartphone has the power to transform the way health care is practiced and to put patients back in control of their health care. Dr. Eric Topol, joins us to talk about his recent book, “The Patient Will See You Now”. A practicing cardiologist, professor of genomics, and director of Scripps Translational Science Institute in La Jolla, CA, Dr. Topol outlines the beginnings of what he believes is a long-overdue shift in medicine that will put the future of medicine in consumer’s hands. That change will have profound effects on all aspects of our b...2015-11-0823 min