Shows
Neuro-Oncology: The PodcastThe proteomic landscape of diffuse midline gliomaDr. Iyad Alnahhas interviews Drs. Cynthia Hawkins and Arun Vadivel about their recent manuscript entitled: "The proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases", published online in Neuro-Oncology in February 2025. More Information2025-05-1716 minNeuro-Oncology: The PodcastRadio-Pathomic maps and MR perfusionDr. Iyad Alnahhas interviews Dr. Peter LaViolette about his and his team's recent manuscript entitled: "Multi-Site Retrospective Analysis of Diffusion and Perfusion MRI Correlates to Glioma Characteristics Derived from Radio-Pathomic Maps", published online in Neuro-Oncology in February 2025.2025-04-1820 minNeuro-Oncology: The PodcastKL-50 in post TMZ MMR-deficient GBMDr. Iyad Alnahhas interviews Dr. Craig Horbinski about his and his team's recent manuscript entitled "The novel DNA cross-linking agent KL-50 is active against patient-derived models of new and recurrent post-temozolomide mismatch repair-deficient glioblastoma", published online in Neuro-Oncology in December 2024.2025-02-2221 minNeuro-Oncology: The PodcastMeasurable disease per FET-PET vs MRI in GBMDr. Iyad Alnahhas interviews Dr. Nathalie Albert about her and her team's recent manuscript entitled: "Measurable disease as baseline criterion for response in glioblastoma: A comparison of PET-based (PET RANO 1.0) and MRI-based (RANO) assessments", published online in Neuro-Oncology in January 2025.2025-02-0814 minNeuro-Oncology: The PodcastPre-radiation chemotherapy in GBMDr. Iyad Alnahhas interviews Dr. Danielle Bazer about her and her team's recently published manuscript, entitled: Using a Pre-Radiation Window to Identify Potentially Active Cytotoxic Agents in Adults with Newly Diagnosed Glioblastoma", published online in Neuro-Oncology in November 2024.2025-01-2013 minNeuro-Oncology: The PodcastResidual tumor volume and survival after CCNU/TMZ in GBMDr. Iyad Alnahhas interviews Drs. Thomas Zeyen and Johannes Weller about their recent manuscript entitled: "Quantitative assessment of residual tumor is a strong and independent predictor of survival in methylated glioblastoma following radiochemotherapy with CCNU/TMZ", published online in Neuro-Oncology in October 2024.2024-11-2413 minNeuro-Oncology: The PodcastEquity-driven applications of AI in neuro-oncologyDr. Iyad Alnahhas interviews Dr. Mulki Mehari about her and her team's recent manuscript entitled: "Enhancing neuro-oncology care through equity-driven applications of artificial intelligence", published online in Neuro-Oncology in August 2024.2024-10-0922 minNeuro-Oncology: The PodcastContemporary molecular prognostic signatures in gliomaDr. Iyad Alnahhas interviews Dr. Linda Bi, Hia Ghosh and Ruchit Patel about their recent manuscript entitled: "Contemporary Prognostic Signatures and Refined Risk Stratification of Gliomas: An Analysis of 4400 Tumors", published online in Neuro-Oncology in August 2024. More Information: https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noae164/77376882024-08-3020 minNeuro-Oncology: The PodcastFDG PET in PCNSLDr. Iyad Alnahhas interviews Drs. Minyoung Oh and Hyungwoo Cho about their recent manuscript entitled: "Enhancing Prognostication and Treatment Response Evaluation in Primary CNS Lymphoma with 18F-FDG PET/CT", published online in Neuro-Oncology in August 2024. Link to manuscript2024-08-1009 minNeuro-Oncology: The PodcastCancer stems cell in GBMDr. Iyad Alnahhas interviews Drs. Justin Lathia and Marco Gallo about their recent manuscript entitled "Cancer stem cell hypothesis 2.0 in glioblastoma: where are we now and where are we going?", published online in Neuro-Oncology in May 2024.2024-06-2131 minNeuro-Oncology: The PodcastLong-term outcomes of pediatric patients with optic pathway gliomaDr. Iyad Alnahhas interviews Drs. Alice Morin, Samuel Abbou and Brice Fresneau about their recent manuscript entitled "Very long-term outcomes of pediatric patients treated for optic pathway gliomas: a longitudinal cohort study" published online in Neuro-Oncology in March 2024. Read Paper2024-05-0415 minNeuro-Oncology: The PodcastLiquid biopsy in CNS lymphomaDr. Iyad Alnahhas interviews Dr. Ricardo Soffietti about the recent RANO review entitled "Liquid biopsy for improving diagnosis and monitoring of CNS lymphomas: a RANO review" published online in Neuro-Oncology in March 2024. Read the paper2024-03-1521 minNeuro-Oncology: The PodcastGlioma genetic profiles and electrophysiologic hyperexcitabilityDr. Iyad Alnahhas interviews Dr. Steven Tobochnik about his and his team's recent manuscript entitled "Glioma genetic profiles associated with electrophysiologic hyperexcitability", published online in Neuro-Oncology in Sep 2023. Read paper2024-01-2622 minNeuro-Oncology: The PodcastThe Biology of H3K27M Mutant GliomasDr. Iyad Alnahhas interviews Dr. Amanda Saratsis about her recent manuscript entitled: "H3K27M Mutant Glioma: Disease Definition and Biological Underpinnings", published online in Neuro-Oncology in October 2023. Read Paper2023-12-2314 minNeuro-Oncology: The PodcastDendritic cell vaccines in gliomas Dr. Iyad Alnahhas interviews Drs. Kelly Hotchkiss and Mustafa Khasraw about their recently published review entitled: "Dendritic cell vaccine trials in gliomas: untangling the lines", published online in Neuro-Oncology in June 2023. Read Paper2023-09-0917 minNeuro-Oncology: The PodcastIntrathecal trastuzumab for leptomeningeal metastases Dr. Iyad Alnahhas interviews Drs. Priya Kumthekar and Jeffrey Raizer about their recent manuscript entitled: A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2- positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics", published online in Neuro-Oncology in March 2023.2023-08-1121 minNeuro-Oncology: The PodcastShort term topiramate for radiation induced cytotoxic edema Dr. Iyad Alnahhas interviews Drs. Maria Jose Contreras-Zarate and Diana Cittelly about their recent manuscript entitled: "Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis", published online in Neuro-Oncology in April 2023. Read Paper2023-07-2114 minNeuro-Oncology: The PodcastRANO resect Dr. Iyad Alnahhas interviews Dr. Philipp Karschnia about his and his team's recent manuscript entitled "Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group", published online in Neuro-Oncology in May 2023. 2023-06-2420 minNeuro-Oncology: The PodcastChanges in survival outcomes in melanoma patients with brain metastases Dr. Iyad Alnahhas interviews Drs. Sherise Ferguson and Michael Davies about their recent manuscript entitled: "Changes in Outcomes and Factors Associated with Survival in Melanoma Patients with Brain Metastases", published online in Neuro-Oncology in December 2022. Read Paper2023-04-2119 minNeuro-Oncology: The PodcastMitotic count prognostic significance in IDH-mutant astrocytoma in the molecular era Dr. Iyad Alnahhas interviews Dr. Max Kros about his and his team's recent manuscript entitled: "Mitotic count is prognostic in IDH-mutant astrocytoma without homozygous deletion of CDKN2A/B. Results of consensus panel review of EORTC trials 26053 and EORTC 22033-26033", published online in Neuro-Oncology in December 2022. Read Paper2023-03-0312 minNeuro-Oncology: The PodcastPalliative care in neuro-oncologyDr. Iyad Alnahhas interviews Drs. Tobias Walbert and Johan Koekkoek about their recent manuscript entitled "Palliative care and end-of-life care in adults with malignant brain tumors", published online in Neuro-Oncology in October 2022 Read Paper2023-02-1030 minNeuro-Oncology: The PodcastThe role of T lymphocytes in the glioma pathobiology Dr. Iyad Alnahhas interviews Dr. David Gutmann about the review entitled "T lymphocytes as dynamic regulators of glioma pathobiology", published online in Neuro-Oncology in March 2022. Read paper2022-12-0216 minNeuro-Oncology: The PodcastBrain metastases; a SNO consensus review: Part 2 In this second of two episodes, Dr. Iyad Alnahhas interviews Drs. Ross Camidge, Michael Davis, Nancy Lin and Ayal Aizer about the recent editorial review entitled: "Brain Metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions", published online in Neuro-Oncology in June 2022. Full Report 2022-09-0933 minNeuro-Oncology: The PodcastBrain metastases; a SNO consensus review: Part 1 In this first of two episodes, Dr. Iyad Alnahhas interviews Drs. Ayal Aizer, Eudocia Lee and Veronica Chiang about the recent editorial review entitled: "Brain Metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions", published online in Neuro-Oncology in June 2022. Full Report2022-08-2627 minNeuro-Oncology: The PodcastPediatric IDH mutant gliomas Dr. Iyad Alnahhas interviews Drs. Jennifer Cotter and Kee Kiat Yeo about their recent paper entitled: ""Multi-institutional study of the frequency, genomic landscape and outcome of IDH-mutant glioma in pediatrics", published online in Neuro-Oncology in May 2022. Full Article2022-08-1319 minNeuro-Oncology: The PodcastSelumetinib in children with NF1 and plexiform neurofibroma Dr.Iyad Alnahhas interviews Drs. Andrea Gross and Brigitte Widemann about their manuscript entitled "Selumetinib in Children with Neurofibromatosis Type 1 and Asymptomatic Inoperable Plexiform Neurofibroma at Risk for Developing Tumor-Related Morbidity", published online in Neuro-Oncology in April 2022. Full Article2022-07-0123 minNeuro-Oncology: The PodcastCell-free DNA from CSF in pediatric, adolescent and young adult patients Dr. Iyad Alnahhas interviews Dr. Matthias Karajannis about his and his team's recent manuscript entitled: "Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult (AYA) brain tumor patients", published in Neuro-Oncology in February 20222022-04-2210 minNeuro-Oncology: The PodcastH3K27M cell-free tumor DNA tracking in response to ONC201 treatment for diffuse midline glioma Dr. Iyad Alnahhas interviews Dr. Carl Koschmann about his and his team's recent manuscript entitled: "Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma" published online in Neuro-Oncology in February 2022. Read the Study2022-03-2522 minNeuro-Oncology: The PodcastTrabectedin for recurrent grade 2 or 3 meningiomas Dr. Iyad Alnahhas interviews Dr. Matthias Preusser about the recent manuscript entitled: "Trabectedin for recurrent WHO grade 2 or 3 meningioma: a randomized phase 2 study of the EORTC Brain Tumor Group (EORTC-1320-BTG)", published online in Neuro-Oncology in October 2021.2022-01-2817 minNeuro-Oncology: The PodcastGlioblastoma cell heterogeneity and plasticity Dr. Iyad Alnahhas interviews Drs. Simone Niclou and Anna Golebiewska about their recent manuscript, entitled: 'Cancer Cell Heterogeneity and Plasticity: A Paradigm Shift in Glioblastoma', published online in Neuro-Oncology in December 2021.2022-01-1413 minNeuro-Oncology: The PodcastResection for recurrent brain metastases Dr. Iyad Alnahhas interviews Dr. Alexander Hulsbergen about his and his team's recent manuscript entitled: "Neurosurgical resection for locally recurrent brain metastases", published online in Neuro-Oncology in July 2021.2021-11-1216 minNeuro-Oncology: The PodcastDNA methylation profiles within the CATNON trialDr. Iyad Alnahhas interviews Dr. Pim French about his and his team recent manuscript entitled: "Prognostic significance of genome-wide DNA methylation profiles within the randomised, phase 3, EORTC CATNON trial on non-1p19q deleted anaplastic glioma", published online in Neuro-Oncology in April 20212021-09-1717 minNeuro-Oncology: The PodcastTesting methods for MGMT promoter methylation Dr. Iyad Alnahhas interviews Dr. Kathreena Kurian about her and her team's recent manuscript entitled: "MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Review", published online in Neuro-Oncology in April 2021.2021-07-2313 minNeuro-Oncology: The PodcastPosterior fossa syndrome Dr. Iyad Alnahhas interviews Dr. Raja Khan about their recent manuscript entitled "Clinical features, neurologic recovery, and risk factors of post-operative posterior fossa syndrome and delayed recovery: a prospective study", published online in April 2021 in Neuro-Oncology.2021-06-1821 minNeuro-Oncology: The PodcastBrain radiotherapy and decline in fine motor skills Dr. Iyad Alnahhas interviews Dr. Jona Hattangadi-Gluth and Ms. Mia Salans about their recently published manuscript entitled: "Longitudinal change in fine motor skills after brain radiotherapy and in vivo imaging biomarkers associated with decline" published online in February 2021 in Neuro-Oncology.2021-04-0918 minNeuro-Oncology: The PodcastA serum based DNA methylation assay to detect gliomas Dr. Iyad Alnahhas interviews Dr. Houton Noushmehr about his recent paper "A serum-based DNA methylation assay provides accurate detection of glioma", published online in Feb 2021 in Neuro-Oncology2021-03-2633 minNeuro-Oncology: The PodcastThe incidence of brain metastases among patients with metastatic breast cancer Dr. Iyad Alnahhas interviews Dr. Katarzyna Jerzak about her recent paper “The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis”, published online in Neuro-Oncology in December, 2020. 2021-02-1223 minNeuro-Oncology: The PodcastA large longitudinal study of patients with Neurofibromatosis Type 2.Dr. Iyad Alnahhas interviews Dr. Gareth Evans about his recent paper in Neuro-Oncology entitled: "Disease course of Neurofibromatosis Type 2; a 30-year follow-up study of 353 patients seen at a single institution2021-01-1520 minNeuro-Oncology: The PodcastVorinostat and bevacizumab for recurrent glioblastoma Dr. Iyad Alnahhas interviews Drs. Vinay Puduvalli and Ying Yuan about their paper "A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma" published in Neuro-Oncology in March 20202021-01-0132 minNeuro-Oncology: The PodcastA subset of pediatric thalamic gliomas Dr. Iyad Alnahhas talks with Dr. Felix Sahm about his recently published article in Neuro-Oncology entitled: "A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR," published online on November 1, 2020.2020-12-1820 minNeuro-Oncology: The PodcastAnnouncing Neuro-Oncology: The PodcastDr. Iyad Alnahhas, producer, introduces the new podcast.2020-11-1900 min