Shows
Addiction Medicine Journal Club62. Naltrexone Pills vs Injections for Alcohol Use DisorderIn episode 62 we discuss the
article “Oral vs Extended-Release Injectable Naltrexone for
Hospitalized Patients with Alcohol Use Disorder.”
Magane KM, et al.Oral
vs Extended-Release Injectable Naltrexone for Hospitalized Patients
With Alcohol Use Disorder: A Randomized Clinical Trial.
JAMA Intern Med. 2025 Jun 1;185(6):635-645.
We also discuss reduced
overdose deaths and changes in buprenorphine labelling to include
higher doses.
NPR:Drug
deaths plummet among young Americans as fentanyl carnage eases
Federal Register:Modifications
to Labeling of Buprenorphine-Containing Transmucosal Products for the
...2025-07-1436 minAddiction Medicine Journal Club61. Safety of BuprenorphineNaloxone vs. Buprenorphine in PregnancyIn episode 61 we discuss pregnancy outcomes with bup/nlx compared to bup alone.
Straub L, et al. Comparative Safety of In Utero Exposure to Buprenorphine Combined With Naloxone vs Buprenorphine Alone. JAMA. 2024 Sep 10;332(10):805-816. doi: 10.1001/jama.2024.11501.
We also discuss the elimination of SAMHSA and methamphetamine-related deaths.
STAT News: Trump’s mental health and addiction problem
New York Times: As Fentanyl Deaths Slow, Meth Comes for Maine
---
This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To...2025-06-1634 minAddiction Medicine Journal Club60. Lisdexamfetamine for methamphetamine use disorderIn episode 60 we discuss treating methamphetamine use disorder with lisdexamfetamine (Vyvanse).
Ezard N, et al; The LiMA Investigator Group. Lisdexamfetamine in the treatment of methamphetamine dependence: A randomised, placebo-controlled trial. Addiction. 2024 Dec 19.
We also discuss why some people don’t get hangovers, and tianeptine, otherwise known as gas station heroin.
New York Times:The People Who Never Get Hangovers
Pain Therapeutics:Tianeptine, an Antidepressant with Opioid Agonist Effects: Pharmacology and Abuse
Potential, a Narrative Review
---
This podcast offers ca...2025-05-2642 minAddiction Medicine Journal Club59. Low-Dose Buprenorphine Initiation (Micro-induction)In episode 59 we discuss outpatient low-dose initiation of buprenorphine.
Suen LW, et al. Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl. JAMA Netw Open. 2025 Jan 2;8(1):e2456253.
We also discuss impulse control dysregulation from ropinerole, and the new non-opioid painkiller, suzetrigine.
BBC:Prescription medication made me a gambling addict
Grall-Bronnec M, et al.Dopamine agonists and impulse control disorders: a complex association. DrugSaf. 2018;41(1):19-75.
FDA:FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pa...2025-05-0534 minAddiction Medicine Journal Club58. Semaglutide for Alcohol Use Disorder (RCT)In episode 58 we discuss a randomized controlled trial of semaglutide for alcohol use disorder.
Hendershot CS, Bremmer MP, Paladino MB, Kostantinis G, Gilmore TA, Sullivan NR, Tow AC, Dermody SS, Prince MA, Jordan R, McKee SA, Fletcher PJ, Claus ED, Klein KR. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2025 Feb 12:e244789.
We also discuss benzodiazepine tapering guidelines and new ways to use Sublocade.
ASAM Clinical Practice Guideline on Benzodiazepine Tapering
Sublocade label changes
---
This podc...2025-04-1440 minAddiction Medicine Journal ClubArticles That Changed Our Practice 2025 (Part 2)In this episode we discuss 4 more articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now.
Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial. JAMA. 2024 May 28; 331(20):1722-1731.
Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2417377.
Understanding the shared meaning of recovery from substance use disorders: New findings from the What is Recovery? Study. Substance Abuse: Research and T...2025-03-2432 minAddiction Medicine Journal ClubArticles That Changed Our Practice 2025 (Part 1)In this episode we discuss 4 articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now.Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures. Journal of Substance Use and Addiction Treatment, Volume 158, 2024. 209252, ISSN 2949-8759.Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024 Mar 4;7(3):e243387.Association of Cannabis Use With Cardiovascular Outcomes Among US Adults. J Am Heart Assoc. 2024 Mar 5;13(5):e030178.Association of random and observed urine drug...2025-03-1636 minAddiction Medicine Journal Club57. What is Recovery?In episode 57 we discuss a new definition of recovery.Zemore SE, Ziemer KL, Gilbert PA, Karno MP, Kaskutas LA. Understanding the Shared Meaning of Recovery From Substance Use Disorders: New Findings From the What is Recovery? Study. Subst Abuse. 2023 Sep 15;17:11782218231199372.We also discuss sports betting and why more people aren’t prescribing buprenorphine.STAT News: The misguided reason why providers aren’t prescribing more buprenorphine for opioid use disorderScientific American: How ‘Dark Patterns’ in Sports Betting Apps Keep Users Gambling---This podcast offers category 1 and MATE-ACT...2025-02-2441 minAddiction Medicine Journal Club56. How Many Quit Attempts Does It TakeIn episode 56 we discuss how many attempts it takes to quit using addictive substances.Fontes RM, Tegge AN, Freitas-Lemos R, Cabral D, Bickel WK. Beyond the first try: How many quit attempts are necessary to achieve substance use cessation? Drug Alcohol Depend. 2024 Dec 8;267:112525. doi: 10.1016/j.drugalcdep.2024.112525. Epub ahead of print. PMID: 39719807.We also discuss capping nicotine content in cigarettes and how exercise affects cravings.Reuters: US regulators propose capping nicotine in cigarettes at non-addictive levelsAddictive Behaviors: Ding F, Jia S, Wang P, Liu C, Li Y. Effect...2025-02-1039 minAddiction Medicine Journal Club55. How Buprenorphine Works in PregnancyIn episode 55 we discuss the pharmacokinetics and pharmacodynamics of buprenorphine in pregnancy. Caritis, Steve N. MD; Venkataramanan, Raman PhD. A Pharmacologic Evaluation of Buprenorphine in Pregnancy and the Postpartum Period. Journal of Addiction Medicine ():10.1097/ADM.0000000000001380, September 2, 2024. We also discuss fraud in Baltimore recovery houses, and the doubling of alcohol-related deaths. The New York Times: They Entered Treatment. Drugs, Overdoses and Deaths Followed. The New York Times: Alcohol Deaths Have More Than Doubled in Two Decades, Study Finds --- This podcast offers category...2025-01-2735 minAddiction Medicine Journal Club54. High Daily Doses of BuprenorphineIn episode 54 we discuss an article about 24-mg daily of buprenorphine and behavioral health hospitalizations. Axeen S, Pacula RL, Merlin JS, Gordon AJ, Stein BD. Association of Daily Doses of Buprenorphine With Urgent Health Care Utilization. JAMA Netw Open. 2024 Sep 3;7(9):e2435478. We also discuss the decline in overdose deaths and RFK’s experience with recovery. The White House: Biden-Harris Administration Marks Historic Progress Reducing Overdoses Across the Country The New York Times: ROBERT KENNEDY JR. ADMITS HE IS GUILTY IN POSSESSING HEROIN Robert F. Ke...2025-01-1442 minAddiction Medicine Journal Club53. Methadone Vs. BuprenorphineIn episode 53 we discuss an article comparing treatment retention and mortality in patients who are prescribed methadone vs. buprenorphine/naloxone for treatment of opioid use disorder. Nosyk B, Et al. Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder. JAMA. 2024 Oct 17. We also discuss the Modernizing Opioid Treatment Access Act, engaging non-abstinent patients in treatment, and hostility to medications with the recovery community. Modernizing Opioid Treatment Access Act (MOTAA) (H.R.1359 / S. 644) ASAM: Engagement and Retention of Nonabstinent Patients in Substance Use Treatment STA...2024-12-3039 minAddiction Medicine Journal Club52. Buprenorphine-precipitated Fentanyl WithdrawalIn episode 52 we discuss precipitated withdrawal in the era of fentanyl. Thakrar AP, Et al. Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl. JAMA Netw Open. 2024 Sep 3;7(9):e2435895. We also discuss kratom, brain injury after overdose, and syringe services. The Kratom Sobriety Podcast Making Kratom Safer The Conversation: Brain injury after overdose is a hidden epidemic NIDA: Syringe services for people who inject drugs are enormously effective, but remain underused --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES an...2024-12-1633 minAddiction Medicine Journal Club51. Fun Activities and RecoveryIn episode 51 we discuss the connection between fun activities and success in recovery from substance use disorder. Acuff, S. F., Ellis, J. D., Rabinowitz, J. A., Hochheimer, M., Hobelmann, J. G., Huhn, A. S., & Strickland, J. C. (2024). A brief measure of non-drug reinforcement: Association with treatment outcomes during initial substance use recovery. Drug and Alcohol Dependence, 256, 111092. We also discuss whether people know their PCP can treat addiction, and alcohol use in Ireland. JAMA Network Open: Knowledge, Attitudes, and Beliefs About Opioid Use Disorder Treatment in Primary Care BBC...2024-12-0234 minAddiction Medicine Journal Club41-50 Round-Up41-50. Round-Up Quick summaries of our last 10 (actually 11) articles. 41. Electronic Nicotine-Delivery Systems for Smoking Cessation42. Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures43. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge44 Association of Cannabis Use With Cardiovascular Outcomes Among US Adults45. Association of random and observed urine drug screening with long-term retention in opioid treatment programs46. Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial 47. Extended-Release Injection vs...2024-11-181h 02Addiction Medicine Journal Club50. Kratom Journal ClubIn episode 50 we discuss 3 articles about kratom.We are again joined by our friend Dr. Casey Grover from the Addiction Medicine Made Easy Podcast. Smith KE, Dunn KE, Rogers JM, Grundmann O, McCurdy CR, Garcia-Romeu A, Schriefer D, Swogger MT, Epstein DH. Kratom use as more than a "self-treatment". Am J Drug Alcohol Abuse. 2022 Nov 2;48(6):684-694. Hill K, Grundmann O, Smith KE, Stanciu CN. Prevalence of Kratom Use Disorder Among Kratom Consumers. J Addict Med. 2024 May-Jun 01;18(3):306-312. Broyan, V. R., Brar, J. K., All...2024-11-0453 minAddiction Medicine Journal Club49. Naltrexone/Bupropion for Methamphetamine Use DisorderIn episode 49 we discuss the 12-week follow-up data from the ADAPT-2 trial about using ER injectable naltrexone and bupropion for methamphetamine use disorder. Li MJ, Chau B, Belin T, Carmody T, Jha MK, Marino EN, Trivedi M, Shoptaw SJ. Extended observation of reduced methamphetamine use with combined naltrexone plus bupropion in the ADAPT-2 trial. Addiction. 2024 Jun 10. doi: 10.1111/add.16529. Epub ahead of print. PMID: 38856086. We also discuss fentanyl vaccines, and how easy it is to manufacture fentanyl. The Conversation: A new fentanyl vaccine looks promising – but treating drug addiction...2024-10-2137 minAddiction Medicine Journal ClubKratom: At Least It’s Not FentanylIn this episode we discuss kratom with our friend Dr. Casey Grover of the Addiction Medicine Made Easy podcast. Stay tuned for part 2 coming next, Kratom Journal Club. Tampa Bay Times: Deadly Dose Annals of Internal Medicine Kratom: An Emerging Issue for Research and Physician Education --- This episode is not eligible for CME, but other episodes offer category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ ---
Co-Host: Dr. Casey Grover
Original theme music: composed and perfor...2024-10-1440 minAddiction Medicine Journal Club48. Semaglutide and Alcohol Use DisorderIn episode 48 we discuss the association between semaglutide and alcohol use disorder. Wang, W., Volkow, N.D., Berger, N.A. et al. Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population. Nat Commun 15, 4548 (2024). The Journal of Addiction Medicine: The Efficacy of GLP-1 Agonists in Treating Substance Use Disorder in Patients We also discuss THC products that look like candy, a good podcast on targeted naltrexone, and perioperative opioids.
The LA Times: Surgeons give patients too many opioids. A few simple steps could curb exce...2024-10-0735 minAddiction Medicine Journal Club47. Injectable Vs. Sublingual Buprenorphine for Fentanyl Use DisorderIn episode 47 we discuss the effectiveness of sublingual and injectable buprenorphine for patients with OUD, with and without fentanyl. Nunes EV, Comer SD, Lofwall MR, Walsh SL, Peterson S, Tiberg F, Hjelmstrom P, Budilovsky-Kelley NR. Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2417377. We also discuss the AMA’s Support of drug decriminalization, and the rise of alcohol-related health problems. New York Times: Oregon Is Recriminalizing Drugs. Here’s What Portl...2024-09-2335 minAddiction Medicine Journal Club46. High Dose Meds for Smoking CessationIn episode 46 we discuss using high doses of varenicline and nicotine for smoking cessation. Cinciripini PM, Green CE, Shete S, Minnix JA, Robinson JD, Cui Y, Kim S, Kypriotakis G, Beneventi D, Blalock JA, Versace F, Karam-Hage M. Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial. JAMA. 2024 May 28; 331(20):1722-1731. We also discuss resources for safer substance use, and the recall of dangerous Diamond Shrooms. Yale Program in Addiction Medicine: Resources for Safer Injection and Substance Use San Fran...2024-09-0935 minAddiction Medicine Journal Club45. Urine Drug Screens and Treatment Retention45. Urine Drug Screens and Treatment Retention In episode 45 we discuss urine drug screens and treatment retention. Michener PS, Knee A, Wilson D, Boama-Nyarko E, Friedmann PD. Association of random and observed urine drug screening with long-term retention in opioid treatment programs. Drug Alcohol Depend. 2024 Feb 1;255:111067. We also discuss storing injectable buprenorphine at room temperature and subliminal menthol in cigarettes. Sublocade Prescribing Information (Storage update top of page 40) Andre Luiz Oliveira da Silva, Lauren K. Lempert, Stanton A. Glantz. More than a “char...2024-07-1542 minAddiction Medicine Journal Club44. Cannabis and CV Outcomes44. Cannabis and CV Outcomes In episode 44 we discuss the association between cannabis use and cardiovascular outcomes. Jeffers AM, Glantz S, Byers AL, Keyhani S. Association of Cannabis Use With Cardiovascular Outcomes Among US Adults. J Am Heart Assoc. 2024 Mar 5;13(5):e030178. doi: 10.1161/JAHA.123.030178. Epub 2024 Feb 28. We also discuss the DEA rescheduling cannabis, and the failure of the menthol ban. Department of Justice: Justice Department Submits Proposed Regulation to Reschedule Marijuana Stat News: Biden administration punts menthol cigarette rule indefinitely --- 2024-07-0133 minAddiction Medicine Journal Club43. Alcohol Use Disorder Meds at Hospital DischargeIn episode 43 we discuss prescribing medication for alcohol use disorder at hospital discharge. Bernstein EY, Et al. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024 Mar 4;7(3):e243387. We also discuss grandparents raising grandchildren who’ve lost a parent to drug overdose, and how native peoples are using opioid settlement funds. Department of labor: Grandchildren Being Raised by Grandparents JAMA Psychiatry: Estimated Number of Children Who Lost a Parent to Drug Overdose in the US From 2011 to 2021 KFF News: Tr...2024-06-1734 minAddiction Medicine Journal Club42. The Protective Effect of BuprenorphineIn episode 42 we discuss how buprenorphine protects against fentanyl overdose. Zheng Dai, et al. Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures. Journal of Substance Use and Addiction Treatment, Volume 158, 2024. 209252, ISSN 2949-8759. We also discuss semaglutide for alcohol use disorder. Richards JR, et al. Significant Decrease in Alcohol Use Disorder Symptoms Secondary to Semaglutide Therapy for Weight Loss: A Case Series. J Clin Psychiatry. 2023 Nov 27;85(1):23m15068. --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES an...2024-06-0324 minAddiction Medicine Journal Club41. Vaping for Smoking CessationIn episode 41 we discuss vaping for smoking cessation. Auer R, et al. Electronic Nicotine-Delivery Systems for Smoking Cessation. N Engl J Med. 2024 Feb 15;390(7):601-610. We also discuss the NarxCare addiction risk score and the recent increase in alcohol-related deaths. New York Times: Addiction Risk Scores Won’t Solve the Opioid Crisis CDC: Deaths from Excessive Alcohol Use — United States, 2016–2021 --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go...2024-05-2036 minAddiction Medicine Journal Club31-40 Round-UpQuick summaries of Episodes 31-40. 31. Injection Drug Use Frequency Before and After Take-Home Naloxone Training 32. Trazodone for sleep disturbance in opioid dependent patients maintained on buprenorphine: A double blind, placebo-controlled trial 33. Non-fatal overdose risk associated with prescribing opioid agonists concurrently with other medication: Cohort study conducted using linked primary care, secondary care and mortality records 34. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl 35. Removal of Medicaid Prior Authorization Requirements and Buprenorp...2024-05-061h 03Addiction Medicine Journal Club40. BZD Prescriptions and Overdose RiskIn this episode we discuss drug overdose after benzodiazepine prescriptions for anxiety and depression. Bushnell GA, et al. Drug overdose risk with benzodiazepine treatment in young adults: Comparative analysis in privately and publicly insured individuals. Addiction. 2023. We also talk about the war on recovery treatments and patients leaving the hospital against medical advice. STAT News: The War on Recovery Scientific American: Against Medical Advice: Another Deadly Consequence of Our Opioid Epidemic ---This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Mic...2024-04-2235 minAddiction Medicine Journal Club39. Opioid Abstinence and Cognitive FunctionIn this episode we discuss improvements in cognitive function with opioid abstinence. Kaur, G. Et Al. Effects of Abstinence From Opioid on Neuropsychological Performance in Men With Opioid Use Disorder: A Longitudinal Study. Journal of Addiction Medicine 17(5): p 557-562, 9/10 2023. We also talk about paramedics giving buprenorphine along with naloxone in the field, and the post-acute withdrawal syndrome. St. Louis Public Radio: Missouri pilot program trains EMS crews to give overdose victims addiction meds The Journal of Addiction Medicine: Post-Acute Withdrawal Syndrome ---------- This podc...2024-04-0831 minAddiction Medicine Journal ClubArticles that Changed Our Practice - Part 2In this episode we discuss 5 more articles that changed our addiction medicine practice. Chambers LC, et al. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl. JAMA Netw Open. 2023; 6(9):e2334540. September 2023. (Episode 34) Caponnetto, P., et al. Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial. BMC Med 21, 220 (2023). (Episode 29) Litwin AH, et al. The HERO Study Group. Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial. Lancet Gastroenterol Hepatol. 2...2024-03-2542 minAddiction Medicine Journal ClubArticles that Changed Our Practice - Part 1In this episode we discuss 5 articles that changed our addiction medicine practice. Mahdi Sheikh, et al. Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study. Ann Intern Med.2021;174:1232-1239. [Epub 27 July 2021]. (Episode 4) Santos GM, et al. Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial. Am J Psychiatry. 2022 Dec 1;179(12):915-926. Epub 2022 Oct 26. (Episode 20) Perry, Briana N. MD; et al. Buprenorphine-naloxone Versus Buprenorphine for Treatment of Opioid Use Disorder...2024-03-1138 minAddiction Medicine Journal Club38. Rehab vs. Meds vs. No TreatmentIn episode 38 we discuss an article comparing different treatments (and no treatment) for opioid use disorder.Robert Heimer, Anne C. Black, Hsiuju Lin, Lauretta E. Grau, David A. Fiellin, Benjamin A. Howell, Kathryn Hawk, Gail D’Onofrio, William C. Becker. Receipt of Opioid Use Disorder Treatments Prior to Fatal Overdoses and Comparison to No Treatment in Connecticut, 2016-17. Drug and Alcohol Dependence. 2023.We also discuss stigma against patients with opioid use disorder who need surgery for endocarditis, the first American opioid addiction crisis after the Civil War, and banning me...2024-02-2634 minAddiction Medicine Journal Club37. Injectable Vs. Sublingual Buprenorphine37. Injectable Vs. Sublingual BuprenorphineIn episode 37 we discuss an article comparing injectable and sublingual buprenorphine.Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial. Marsden, John et al. eClinicalMedicine, Volume 66, 102311 We also discuss new data on the teratogenicity of fentanyl, and a new genetic test to identify the risk for opioid use disorder.Genetics on Medicine Open: A novel syndrome associated with prenatal fentanyl exposure2024-02-0546 minAddiction Medicine Journal Club36. FOMO and Smartphone UseIn episode 36 we discuss an article about the mediators of problematic smartphone use.Christiane Arrivillaga, Caleb J. Hallauer, Christian Montag, Jon D. Elhai. Emotion dysregulation factors associated with problematic smartphone use severity: The mediating role of fear of missing out. Addictive Behaviors. Volume 143. 2023. https://doi.org/10.1016/j.addbeh.2023.107708We also discuss the National Survey on Drug Use and Health and Rite Aid’s bankruptcy.SAMHSA: Highlights from the 2022 National Survey on Drug Use and HealthSAMHSA: Results from the 2022 National Survey on Dr...2024-01-1531 minAddiction Medicine Journal Club35. Prior Auths and BuprenorphineIn episode 35 we discuss whether eliminating prior auths leads to more buprenorphine prescribing.Christine PJ, Larochelle MR, Lin L, McBride J, Tipirneni R. Removal of Medicaid Prior Authorization Requirements and Buprenorphine Treatment for Opioid Use Disorder. JAMA Health Forum. 2023;4(10):e233549.We also discuss buprenorphine diversion, and the lack of treatments for stimulant use disorder.Harm Reduction Journal: Examining buprenorphine diversion through a harm reduction lens: an agent-based modeling studyNBC news: Why are there no treatments for cocaine and meth addicti...2024-01-0137 minAddiction Medicine Journal Club34. 24 mg of BuprenorphineIn episode 24 we discuss prescribing 24 mg of buprenorphine daily.Chambers LC, Hallowell BD, Zullo AR, et al. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl. JAMA Netw Open. 2023;6(9):e2334540. September 2023. We also discuss why Rite Aid filed for bankruptcy, and the FDA ban on menthol cigarettes.From the NY Times: Rite Aid, Facing Slumping Sales and Opioid Suits, Files for BankruptcyFrom CNN: FDA takes ‘momentous’ step toward banning menthol cigarette...2023-12-1824 minAddiction Medicine Journal Club33. Polypharmacy and OverdoseIn episode 33 we discuss overdose risk and polypharmacy: opioids, benzodiazepines, antipsychotics, and gabapentinoids.Domzaridou E, Carr MJ, Millar T, Webb RT, Ashcroft DM. Non-fatal overdose risk associated with prescribing opioid agonists concurrently with other medication: Cohort study conducted using linked primary care, secondary care and mortality records. Addiction. 2023 Aug 3.We also discuss treating HIV in primary care, and how eliminating prior auth barriers to buprenorphine does not increase prescribing.The MidAtlantic AIDS Education and Training CenterRemoval of Medicaid...2023-12-0435 minAddiction Medicine Journal Club32. Trazodone for Sleep in OUDIn episode 32 we discuss an article about trazodone for sleep in people with opioid use disorder on buprenorphine.Piyush Goyal, Dheeraj Kattula, Ravindra Rao, Roshan Bhad, Ashwani Kumar Mishra, Anju Dhawan. Trazodone for sleep disturbance in opioid dependent patients maintained on buprenorphine: A double blind, placebo-controlled trial. Drug and Alcohol Dependence. Volume 250. 2023. 110891. ISSN 0376-8716. We also discuss the decriminalization of psychedelics and treating HCV in primary care.From the LA Times: California moves to decriminalize use of magic mushrooms and other natural psychedelics2023-11-2026 min
Dear PatientHow to respond to an opioid overdoseDear Patient,
In this episode I hope to cover a very basic approach to managing an opioid overdose. I wrote this as a bonus episode with the goal helping anyone who finds themselves in a position where they need to respond to an opioid overdose with no other resources. This is not a replacement for seeking medical help and not a replacement for first aid training. I hope you never need this but I recorded this if someone finds themselves in this position. Remember, we are stronger together, the medical community is here for you, and YOU...2023-11-2005 minDear PatientMethadone, Myths, and More InformationDear Patient,
This episode is for all the things I wanted to talk about but that I could not fit in earlier. I touch on Methadone, on some myths surrounding buprenorphine, and additionally give you a few additional resources, and some advice on finding more information. I also take the time to thank the people who helped me make this podcast, and thank-you for listening. I truly hope this has helped you on your path to making you your best self. We are stronger together, so remember should you ever need help, there are people who are...2023-11-2008 minDear PatientWhat can you do to be safer if you are continuing to use illegal opioidsDear Patient,
In this episode I would like to talk to anyone who continues to use illegal opioids despite our recommendation not to use these drugs. I feel that providing education on how to use these drugs in the safest way possible is important and I hope this information allows you to be your safest self.
Remember if you ever find yourself in a position where you would like to seek help, the medical community is here for you. We are stronger together, and YOU ARE NOT ALONE.
Dr. John Keenan Fanning
2023-11-2007 minDear PatientChronic Pain - Can Buprenorphine HelpDear Patient,
In this episode I continue to talk about Buprenorphine, but rather then talk about it from the side of opioid use disorder I hope to educate you about how this medication can be used to treat chronic pain. While opioids are generally poor for chronic pain, may people find themselves taking long term opioids in attempts to treat this pain. If you are currently using and opioids and you have concerns about your use I am here to give you the knowledge to inform yourself. You are a part of your health care team, and...2023-11-2008 minDear PatientBurprenorphine - What are the DrawbacksDear Patient,
In this episode I am excited to talk about Buprenorphine! This is one of the treatment options available for opioid use disorder. In this episode I discuss the drawbacks of this treatment to give you the knowledge to help yourself. If you every would like to seek help, remember, the medical community is here for you. YOU ARE NOT ALONE.
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this podcast. Without his amazing guidance and suggestions this podcast would not have been...2023-11-1909 minDear PatientBuprenorphine - What are the benefitsDear Patient,
In this episode I am excited to talk about Buprenorphine! This is one of the treatment options available for opioid use disorder. In this episode I discuss the benefits of this treatment and in the next episode I discuss the drawbacks. If you every would like to seek help, remember, the medical community is here for you. YOU ARE NOT ALONE.
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this podcast. Without his amazing guidance and suggestions this podcast would not have...2023-11-0807 minDear PatientNaloxone - How it WorksDear Patient,
In this episode I cover what Naloxone is and how it works. If you every would like to seek help, remember, the medical community is here for you. YOU ARE NOT ALONE.
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this podcast. Without his amazing guidance and suggestions this podcast would not have been possible! Additionally I owe thanks to Dr. Kathryn Dong who provided useful edits for this episode.
2023-11-0804 minDear PatientThe Risks of Opioid UseDear Patient,
In this episode I cover the Risks of opioids, specifically the risks of opioids themselves, but I would also the risks of how you use opioids. This information is not meant as a scare tactic but rather as a way for you to inform yourself and understand the risk of ongoing opioid use. If you every would like to seek help, remember, the medical community is here for you. YOU ARE NOT ALONE.
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this...2023-11-0808 minDear PatientHow Opioids WorkDear Patient,
In this episode I cover how opioids work. I focus on 3 big effects including 1) how they are pain killers, 2) how they can make you feel good, and 3) how they can make you stop breathing. This information is meant as a starting place to enable you to become your best self. Remember, YOU ARE NOT ALONE.
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this podcast. Without his amazing guidance and suggestions this podcast would not have been possible! Additionally I owe thanks...2023-11-0707 minAddiction Medicine Journal Club31. Naloxone and IV Drug Use31: We discuss an article about how naloxone training impacts IV drug use.Colledge-Frisby S, Rathnayake K, Nielsen S, et al. Injection Drug Use Frequency Before and After Take-Home Naloxone Training. JAMA Netw Open. 2023;6(8):e2327319. We also discuss gambling self-exclusion and which professions use the most drugs.From the Pennsylvania Gaming Control Board: Gambling Self-Exclusion From the CDC: Drug Overdose Mortality by Usual Occupation and Industry Two other podcasts on naloxone:The Addiction in Emergency...2023-11-0628 minDear PatientThe Link Between Isolation Trauma and Substance Use DisorderDear Patient,
In this episode I talk about the HUGE link between past traumas, isolation and substance use disorder. I hope this makes you recognize that if you are someone who has experienced trauma in your past it is okay to ask for help. Further I want to stress that there is help out there if you ask for it. Remember, YOU ARE NOT ALONE!
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this podcast. Without his amazing guidance and suggestions this podcast would...2023-10-2806 minDear PatientIntroductionDear Patient,
This episode is an introduction to my podcast, and covers a a description of the 4 C’s of addiction. Remember, YOU ARE NOT ALONE.
Dr. John Keenan Fanning
P.S. I need to thank Dr. Landon Berger for his contributions to this podcast. Without his amazing guidance and suggestions this podcast would not have been possible! Additionally I owe thanks to Dr. Kathryn Dong who provided useful edits for this episode.
2023-10-2804 minAddiction Medicine Journal Club30. Race and MOUDIn episode 30 we discuss an article about racial differences in the receipt of medications for opioid use disorder.Barnett ML, Meara E, Lewinson T, Hardy B, Chyn D, Onsando M, Huskamp HA, Mehrotra A, Morden NE. Racial Inequality in Receipt of Medications for Opioid Use Disorder. N Engl J Med. 2023 May 11;388(19):1779-1789.We also talk about opioid poisonings among children under 6, and the Cannabis Users Restoration of Eligibility (CURE) Act.From the journal Pediatrics: Characteristics of Fatal Poisonings Among Infants and Young Children in...2023-10-0938 minAddiction Medicine Journal Club29. Vaping CessationIn episode 29 we discuss an article about using varenicline and counseling for vaping cessation..Caponnetto, P., Campagna, D., Ahluwalia, J.S. et al. Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial. BMC Med 21, 220 (2023).In other vaping-related news:From NYSCSH: Vape pens that look like highlightersFrom the Surgeon General: Risk of e-cigarettes and how to take actionHow can you protect your kids (and other people’s kids): The Campaign for Tobacco-free kids----------This podcast of...2023-09-2533 minAddiction Medicine Journal Club28. Pain and RecoveryIn episode 28 we discuss an article about pain and addiction recovery.Ajay Manhapra, Elina A. Stefanovics, Taeho Greg Rhee, Robert A. Rosenheck, Persistence of significant pain interference following substance use disorder remission: Negative association with psychosocial and physical recovery, Drug and Alcohol Dependence, Volume 232, 2022, 109339, ISSN 0376-8716, We also discuss top-selling flavored e-cigarette products, and Sweden becoming the first smoke-free country. Scripps News: Sweden Close to Becoming the Frist Smoke-Free Country in EuropeJAMA Network Open: Evaluation of statewide restrictions on...2023-09-1137 minAddiction Medicine Journal Club27. The First Opioid PrescriptionIn episode 27 we discuss an article about the risk of developing opioid use disorder after the first opioid prescription.Kendler, K., Lönn, S., Ektor-Andersen, J., Sundquist, J., & Sundquist, K. (2022). Risk factors for the development of opioid use disorder after first opioid prescription: A Swedish national study. Psychological Medicine, 1-9. From JAMA: Physicians’ actions to help end the nation’s drug-related overdose and death epidemic—and what still needs to be done. ---------This episode is eligible for CME credit from MICARES and Michigan State Universi...2023-08-2834 minAddiction Medicine Journal Club26. Addiction Survivors26. We discuss a new conceptual model of addiction recovery.Pytell, J.D., Chander, G., Thakrar, A.P. et al. Pytell, J.D., Chander, G., Thakrar, A.P. et al. Does a Survivorship Model of Opioid Use Disorder Improve Public Stigma or Policy Support? A General Population Randomized Experiment. J GEN INTERN MED 38, 1638–1646 (2023).We also talk about choosing wisely in addiction medicine. What would be on your “Things we do for no reason” list?From the Journal of the Society of Hospital Medicine: Avoiding methadone for opioid withdra...2023-08-1536 minAddiction Medicine Journal Club25. High-dose Buprenorphine Induction25. We discuss an article about high-dose buprenorphine induction.Herring AA, Vosooghi AA, Luftig J, et al. High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder. JAMA Netw Open. 2021;4(7):e2117128.From NPR: Drugmaker Mallinckrodt may renege on $1.7 billion opioid settlement----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn...2023-07-1731 minAddiction Medicine Journal Club24. Smoking Cessation and Mortality24. We discuss updated data on the harms of smoking and the benefits of quitting.Thomson B, Emberson J, Lacey B, et al. Association Between Smoking, Smoking Cessation, and Mortality by Race, Ethnicity, and Sex Among US Adults. JAMA Netw Open. 2022;5(10):e2231480.We also discuss the drug supply shift from heroin to fentanyl, and how California wants to decriminalize psychedelics.CDC: Rapid Analysis of Drugs: A Pilot Surveillance System To Detect Changes in the Illicit Drug Supply To Guide Timely Harm Reduction Responses — Eight Syringe Serv...2023-07-0335 minAddiction Medicine Journal Club23. Eat-Sleep-Console23. We discuss an article about the Eat-Sleep-Console approach to treat neonatal opioid withdrawal syndrome.Young LW, Ounpraseuth ST, et. al. ACT NOW Collaborative. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal. N Engl J Med. 2023 Apr 30. doi: 10.1056/NEJMoa2214470. Epub ahead of print. PMID: 37125831.We also share how even nematodes get the endocannabinoid munchies, and semaglutide helps rats with their binge-drinking.
The conserved endocannabinoid anandamide modulates olfactory sensitivity to induce hedonic feeding in C. elegans
Semaglutide reduces alcohol intake and relapse-like drinking in male and female...2023-06-1931 minAddiction Medicine Journal Club22. Contingency Management for Coronary Artery Disease22. Contingency Management for Coronary Artery Disease22: We discuss an article about contingency management and the regression of coronary plaques in HIV+ cocaine users.Lai, Hong PhD; Bluemke, David A. MD; Fishman, Elliot K. MD; Gerstenblith, Gary MD; Celentano, David D. ScD; Treisman, Glenn MD; Foster, Parker MS; Mandler, Raul MD; Khalsa, Jag MS, PhD; Chen, Shaoguang MS; Bhatia, Sandeepan MD; Kolossváry, Márton MD; Lai, Shenghan MD. High-risk Coronary Plaque Regression in Cash-based Contingency Management Intervention Among Cocaine Users With HIV-associated Subclinical Coronary Atherosclerosis. Journal of Addiction Medicine 17(2):p 14...2023-06-0528 minAddiction Medicine Journal Club21. SOAT for OUD: Short-Acting Opioid Agonists for Opioid Use Disorder21: We discuss an article about using short-acting opioids to treat opioid use disorder in the hospital.Thakrar, A.P., Uritsky, T.J., Christopher, C. et al. Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder. Addict Sci Clin Pract 18, 13 (2023). We also discuss compulsory addiction treatment:Why involuntary treatment for addiction is a dangerous ideaMy Son Was Addicted and Refused Treatment. We Needed More Options.Juul is getting sued (too bad, so sad):...2023-05-2237 minAddiction Medicine Journal ClubWhat We Learned at ASAM2023What We Learned at ASAM2023In this episode, we share what we learned at the 2023 American Society of Addiction Medicine Conference.Some links from the conference that you might like:Curbsiders Addiction Medicine PodcastToxIC: Toxicology Investigators ConsortiumDrugsData from the Erowid CenterCESAR: Center for Substance Use, Addiction, and Health Research ---------Episode Credits:
Original theme music: composed and performed by Benjamin Kennedy
Audio production: Erin McCue
Video production: Paul Kennedy
Executive P...2023-05-0841 minAddiction Medicine Journal Club11-20 Round-up11-20 Round-upSuper busy? Here are quick summaries of the last 10 articles.Article list:11. Impact of wine bottle and glass sizes on wine consumption at home: a within- and between- households randomized controlled trial12. Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities13. Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study14. Effects of Early Life Trauma on Risks for Adult Opioid Use Disorder Are Mediated by Stress and Occur Independent of...2023-04-2435 minAddiction Medicine Journal Club20. Targeted Naltrexone for Binge Drinking20. Targeted Naltrexone for Binge DrinkingIn episode 20 we discuss an article about taking naltrexone as needed to reduce binge drinking among sexual and gender minority men.Santos GM, Ikeda J, Coffin P, Walker J, Matheson T, Ali A, McLaughlin M, Jain J, Arenander J, Vittinghoff E, Batki S. Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial. Am J Psychiatry. 2022 Dec 1;179(12):915-926. Epub 2022 Oct 26. We also discuss the recent reduction in the number of o...2023-04-1031 minAddiction Medicine Journal Club19. Patients’ Goals in Treatment19. Patients’ Goals in TreatmentIn episode 19 we discuss an article about what is most important to patients in treatment for opioid use disorder.Reed, M.K., Smith, K.R., Ciocco, F. et al. Sorting through life: evaluating patient-important measures of success in a medication for opioid use disorder (MOUD) treatment program. Subst Abuse Treat Prev Policy 18, 4 (2023). Also, here are the DEA’s proposed telemedicine regulations, and we encourage you to submit public comments by 3/31/23.1. Telemedicine prescribing of controlled substances when...2023-03-2932 minAddiction Medicine Journal Club18. Treating HCV in People Who Inject DrugsIn episode 18 we discuss the Hepatitis C Real Option (HERO) Study about two different models of HCV treatment in people who inject drugs. Litwin AH, Lum PJ, Taylor LE, Mehta SH, Tsui JI, Feinberg J, Kim AY, Norton BL, Heo M, Arnsten J, Meissner P, Karasz A, Mckee MD, Ward JW, Johnson N, Pericot-Valverde I, Agyemang L, Stein ES, Thomas A, Borsuk C, Blalock KL, Wilkinson S, Wagner K, Roche J, Murray-Krezan C, Anderson J, Jacobsohn V, Luetkemeyer AF, Falade-Nwulia O, Page K; HERO Study Group. Patient-centred models of hepatitis C treatment for people who i...2023-03-1340 minAddiction Medicine Journal Club17. Bup-nalox vs. Bup in PregnancyIn episode 17 we discuss buprenorphine-naloxone vs. buprenorphine alone in pregnancy.Perry, Briana N. MD; Vais, Simone MD; Boateng, Jeffery O. MBchB, MPH; Jain, Mayuri MPH; Wachman, Elisha M. MD; Saia, Kelley A. MD. Buprenorphine-naloxone Versus Buprenorphine for Treatment of Opioid Use Disorder in Pregnancy. Journal of Addiction Medicine 16(6):p e399-e404, 11/12 2022.We also discuss opioid-induced urinary retention, and the legalization of psilocybin in Oregon for treatment of alcohol use disorder and depression.Guy M. Goodwin, et. al. Single-Dose Psilocybin for a Treatment-Resistant Episode of...2023-02-2736 minAddiction Medicine Journal Club16. Treating Opioid Use Disorder in Jail16. Treating Opioid Use Disorder in JailIn episode 16 we discuss an article about in-jail medication for opioid use disorder and recidivism.Elizabeth A. Evans, Donna Wilson, Peter D. Friedmann. Recidivism and mortality after in-jail buprenorphine treatment for opioid use disorder. Drug and Alcohol Dependence, Volume 231, 2022, 109254, ISSN 0376-8716.Scott, C.K., Grella, C.E., Dennis, M.L. et al. Availability of best practices for opioid use disorder in jails and related training and resource needs: findings from a national interview study of jails in heavily...2023-02-1328 minAddiction Medicine Journal Club15. Buprenorphine vs. Methadone in PregnancyIn episode 15 we discuss buprenorphine vs. methadone in pregnancy.E.A. Suarez, K.F. Huybrechts, L. Straub, S. Hernández‑Díaz, H.E. Jones, H.S. Connery, J.M. Davis, K.J. Gray, B. Lester, M. Terplan, H. Mogun, and B.T. Bateman. Buprenorphine versus Methadone for Opioid Use Disorder in Pregnancy. N Engl J Med 2022; 387:2033-2044. Bruzelius E, Martins SS. US Trends in Drug Overdose Mortality Among Pregnant and Postpartum Persons, 2017-2020. JAMA. 2022;328(21):2159–2161. We also discuss opioid use disorder in our geriatric patients, and opening a new bu...2023-01-3034 minAddiction Medicine Journal Club14. Early Life Trauma and Opioid Use DisorderIn episode 14 we discuss the connection between early life trauma, depression, anxiety, stress, and opioid use disorder.Effects of Early Life Trauma on Risks for Adult Opioid Use Disorder Are Mediated by Stress and Occur Independent of Depression and Anxiety. Dunn, Kelly E. PhD, MBA; Turner, Gavin M. BS; Oswald, Lynn M. PhD. Journal of Addiction Medicine: 11/12 2022 - Volume 16 - Issue 6 - p 709-715 doi: 10.1097/ADM.0000000000001011We also discuss an opinion piece on AMA discharges and the new fentanyl vaccine.Retiring the “Against Medical Adv...2023-01-0929 minAddiction Medicine Journal Club13. Prescription Opioids and Cognitive DeclineIn episode 13 we discuss opioids and cognitive changes in older adults.Warner, NS, Hanson, AC, Schulte, PJ, Habermann, EB, Warner, DO, Mielke, MM. Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study. J Am Geriatr Soc. 2022; 1- 12. doi:10.1111/jgs.18030 https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.18030----------We also discuss the new (and old) CDC opioid prescribing guidelines.----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go...2023-01-0225 minAddiction Medicine Journal Club12. Methamphetamine and Opioid Overdose in Rural CommunitiesIn episode 12 we discuss overdoses related to methamphetamine and opioid use in rural areas.Korthuis PT, Cook RR, Foot CA, et al. Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities. JAMA Netw Open. 2022;5(8):e2226544. doi:10.1001/jamanetworkopen.2022.26544 August 2022Rural Opioid Initiative----------We also discuss building community in addiction medicine.
ASAM Connect
Addiction Medicine Doctors Facebook group
ASAM annual meeting
List of available ECHOs
----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for...2022-12-1931 minAddiction Medicine Journal Club11. Wine Bottle and Wineglass SizeIn episode 11 we discuss an article about the impact of wine bottle and glass size on consumption.Mantzari, E, Ventsel, M, Ferrar, J, Pilling, MA, Hollands, GJ, Marteau, TM. Impact of wine bottle and glass sizes on wine consumption at home: a within- and between- households randomized controlled trial. Addiction. 2022. ----------We discuss non-abstinence-based resources for addressing unhealthy alcohol use
Rethinking Drinking
Moderation Management
Dry January
Alcohol Harm Reduction Tips
We also talk about calling to check in on patients who have been lost to follow-up. ----------Th...2022-12-0528 minAddiction Medicine Journal Club1-10. Round-upShort on time? In this episode we give you quick summaries of articles 1-10.
Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease
Analysis of Stimulant Prescriptions and Drug-Related Poisoning Risk Among Persons Receiving Buprenorphine Treatment for Opioid Use Disorder
Association of Dose Tapering With Overdose or Mental Health Crisis Among Patients Prescribed Long-term Opioids
Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study
Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults: A Randomized Clinical Trial
Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol...2022-11-2144 minAddiction Medicine Journal Club10. Buprenorphine TaperingIn episode 10 we discuss an article about buprenorphine tapering.Bozinoff N, Men S, Kurdyak P, Selby P, Gomes T. Prescribing Characteristics Associated With Opioid Overdose Following Buprenorphine Taper. JAMA Netw Open. 2022;5(9):e2234168. ----------Take a look at Riggs, KR, DeRussy, AJ, Leisch, L, et al. Sensitivity of health records for self-reported nonfatal drug and alcohol overdose. Am J Addict. 2022; 1- 6. We also discuss the federal government’s plan to provide care for people with opioid use disorder during pregnancy. Watch Mat...2022-11-0735 minAddiction Medicine Journal Club9. Psilocybin for Alcohol Use DisorderIn episode 9 we discuss psilocybin for treating alcohol use disorder.Bogenschutz MP, Ross S, Bhatt S, et al. Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022;79(10):953–962.----------We talk about Wal-Mart and CVS not filling some telemedicine prescriptions.We also discuss gabapentin involvement in overdose deaths and the efficacy of gabapentin for neuropathic pain.Mattson CL, Chowdhury F, Gilson TP. Notes from the...2022-10-2440 minAddiction Medicine Journal Club8. Opioid Tapering and Risk of Suicide and OverdoseIn episode 8 we discuss the article about opioid tapering and discontinuation, and the risks of suicide and overdose.Larochelle MR, Lodi S, Yan S, Clothier BA, Goldsmith ES, Bohnert ASB. Comparative Effectiveness of Opioid Tapering or Abrupt Discontinuation vs No Dosage Change for Opioid Overdose or Suicide for Patients Receiving Stable Long-term Opioid Therapy. JAMA Netw Open. 2022;5(8):e2226523.We also discuss the recent Ruan vs. United States supreme court decision about pill mills.----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES a...2022-10-1035 minAddiction Medicine Journal Club7. Treating Opioid and Polysubstance Use DisordersIn Episode 7 we discuss treating opioid use disorder with co-occurring polysubstance use.Xu KY, Mintz CM, Presnall N, Bierut LJ, Grucza RA. Comparative Effectiveness Associated With Buprenorphine and Naltrexone in Opioid Use Disorder and Cooccurring Polysubstance Use. JAMA Netw Open. 2022;5(5):e2211363. 2022 Aug 3. We also discuss the Society of Hospital Medicine’s new consensus statement about management of opioid use disorder in the hospital, and hepatotoxicity from depot buprenorphine.Calcaterra SL, Et. Al. Management of opioid use disorder and associated conditions among hospitalized adults: A Co...2022-09-2634 minAddiction Medicine Journal Club6. A BZD-Sparing Alcohol Withdrawal ProtocolIn episode 6 we discuss a benzodiazepine-sparing alcohol withdrawal protocol.Smith JT, Sage M, Szeto H, et al. Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol Withdrawal Order Set in an Integrated Health Care System. JAMA Netw Open. 2022;5(2):e220158. 2022 Feb 2.We also discuss long-term outcomes from a primary-care based MAT clinic, and the movement to deregulate methadone and expand access.Cope K, DeMicco J, Salib J, Michael M, Yakoub P, Daoud K, Cope R. Three-year Retention Rates With Office-based Treatment of Buprenorphine for Opioid Use Disorder i...2022-09-1227 minAddiction Medicine Journal Club5. Clinical Effects of Medical Marijuana CardsEpisode 5 discusses the clinical effects of getting a medical marijuana card.Gilman JM, Schuster RM, Potter KW, et al. Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(3):e222106. If you want an introduction on how to manage medical marijuana in primary care, listen to this awesome episode from The Curbsiders. We also discuss ASAM Connect, and how to get more PCPs into addiction medicine.If y...2022-08-2931 minAddiction Medicine Journal Club4. Smoking Cessation After Lung Cancer DiagnosisEpisode 4 discusses the benefits of smoking cessation after a diagnosis of lung cancer.Mahdi Sheikh, Anush Mukeriya, Oxana Shangina, et al. Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study. Ann Intern Med.2021;174:1232-1239. [Epub 27 July 2021].We also talk about whether or not increased buprenorphine prescribing will lead patients to be placed on it inappropriately, and some of the hurdles faced when trying to prescribe medications for opioid use disorder in the hospital.To make sure you’re prescribing buprenorphine co...2022-08-1525 minAddiction Medicine Journal Club2: Prescribing Stimulants for Patients on BuprenorphineIn episode 2 we discuss the safety of prescribing stimulants for patients receiving buprenorphine.Article Citation: Mintz CM, Xu KY, Presnall NJ, et al. Analysis of Stimulant Prescriptions and Drug-Related Poisoning Risk Among Persons Receiving Buprenorphine Treatment for Opioid Use Disorder. JAMA Netw Open. 2022;5(5):e2211634. doi:10.1001/jamanetworkopen.2022.11634We also discuss marketing of flavored tobacco and nicotine products to children.----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make...2022-08-0226 minAddiction Medicine Journal Club3. Opioid Tapering and Overdoses and Mental Health CrisesIn episode 3 we discuss the risks of tapering for patients on long-term, high-dose opioids.Article citation: Agnoli, A., Xing, G., Tancredi, D. J., Magnan, E., Jerant, A., & Fenton, J. Association of Dose Tapering With Overdose or Mental Health Crisis Among Patients Prescribed Long-term Opioids. JAMA, 326(5), 411–419. August 3, 2021.We also discuss how to get your DEA waiver to prescribe buprenorphine in just 5 minutes.If you want to start prescribing buprenorphine right away take a look at the SAMHSA quick-start guide, or the ASAM one-hour mini-course.----------This podcast offers category 1 and MATE...2022-08-0237 minAddiction Medicine Journal Club1. The Cardiovascular Effects of AlcoholIn Episode 1 we discuss the article “Association of Habitual Alcohol Intake with Risk of Cardiovascular Disease,” a reexamination of the question of how alcohol intake is related to cardiovascular outcomes, and whether or not the J-curve for risks of alcohol intake actually exists.Article citation: Biddinger KJ, Emdin CA, Haas ME, et al. Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease. JAMA Netw Open. 2022;5(3):e223849. doi:10.1001/jamanetworkopen.2022.3849.We also discuss xylazine as an additive to illicit opioids, and the possible FDA ban on menthol and flavored tobacco produ...2022-07-0431 min
the.rugby.gods_podcastSe.2-Ep.14: The Six Nations ‘21, Rd.4, Mar. 13-14A brief overview of the 3 games in round 4 of the Six Nations 2021.John’s picks: Wales +15, France +10, Scotland +5.https://www.sixnationsrugby.com/fixtures/2021-03-1015 minthe.rugby.gods_podcastSe.2-Ep.13: Private Equity Investment in New Zealand Rugby Pt.2John reads through 2 articles and shares a few thoughts on Private Equity & Investment in New Zealand Rugby. Private Equity in NZR (follow up)https://www.stuff.co.nz/sport/rugby/300221124/nz-rugby-get-465-million-private-investment-offer-from-us-company-report Private Investment in NZ Super Rugby https://www.stuff.co.nz/sport/rugby/super-rugby/300243462/unshackled-new-zealand-rugby-puts-perpetual-licences-on-the-table-for-franchises2021-03-1032 minthe.rugby.gods_podcastSe.2-Ep.11: Mar. 05 - Mar. 07 Super Rugby Aotearoa Rd.2 & Super Rugby AU Rd.3 (Preview)John gives some quick thoughts on the games this weekend:CHI v HIG (Highlanders +3)WAR v FOR (Force +9)BRU v REB (Brumbies +12)CRU v HUR (Crusaders +10)https://super.rugby/superrugby/fixtures/2021-03-0514 minthe.rugby.gods_podcastSe.2-Ep.7: The Six Nations, The Japanese Top League, Super Rugby AU & AotearoaJohn looks around the professional rugby world in Europe and Japan as well as Australia and New Zealand.Six Nationshttps://www.sixnationsrugby.com/fixtures/Japanese Top Leaguehttp://en.rugby-japan.jp/schedule/result/Super Rugby AU / Aotearoa https://super.rugby/superrugby/2021-02-2341 minthe.rugby.gods_podcastSe.2-Ep.6: The Six Nations ‘21, Rd.2, Feb. 13-14A brief overview of the 3 games in round 2 of the Six Nations 2021 with a look at a few players likely to make key contributions.Also a review of results from round 1.John’s picks: England +26, Scotland +5, France +11.https://www.sixnationsrugby.com/fixtures/Join Helston Park Challenge, my Six Nations Predictor league on @Superbru! You can find my pool here:https://www.superbru.com/sixnations/pool.php?p=12300821or by downloading the Superbru app and searching for the pool with code:...2021-02-1234 minthe.rugby.gods_podcastSe.2-Ep.5: The Six Nations ‘21, Rd.1, Feb. 6-7A brief overview of the 3 games in round 1 of the Six Nations 2021 with a look at each team’s spine - 2-8-9-10-15 and a few other players likely to make key contributions.John’s picks: France +15, England +10, Ireland +5. https://www.sixnationsrugby.com/fixtures/Join Helston Park Challenge, my Six Nations Predictor league on @Superbru! You can find my pool here:https://www.superbru.com/sixnations/pool.php?p=12300821or by downloading the Superbru app and searching for the pool with code...2021-02-0522 minthe.rugby.gods_podcastSe.2-Ep.4: The Super Rugby AU 2021 Squads & The JaguaresJohn takes a look at the comings and goings of the Australian Super Rugby clubs before the 2021 season and also has a look at the Jaguares, the club’s disbanding and where their players have moved on to in the world. The Super Rugby AU Squads https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_AU_transfersThe Jaguares https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_transfers2021-01-281h 27the.rugby.gods_podcastSe.2-Ep.3: Private Equity Investment in New Zealand RugbyJohn reads through the article and shares a few thoughts on Private Equity in New Zealand Rugby. Explainer: What private equity investment would mean for New Zealand RugbyPaul Cully 07:27, Jan 20 2021“New Zealand Rugby has been exploring the possibility of private equity investment for at least 12 months.Global giants Silver Lake and CVC are thought to be among those keen to enter a partnership with NZ Rugby, although senior sources played down a UK report suggesting that a Silver Lake deal could be done imminently.2021-01-2229 minthe.rugby.gods_podcastThe Mitre 10 Cup Format: Status Quo or North - South Pools?A look at the Mitre 10 Cup after 10 seasons and the pros and cons of changing the format. Current: Premiership (A) / Championship (B) vs. Proposed: North (BLU CHI) / South (HUR CRU HIG) Pools.John suggests using the current model for Super Rugby as it expands to 12-14 teams. https://www.stuff.co.nz/sport/rugby/provincial/300179992/new-zealand-rugby-needs-more-time-to-decide-on-future-of-mitre-10-cup2020-12-3122 minthe.rugby.gods_podcastThe Super Rugby Aotearoa 2021 SquadsJohn takes a look at all five New Zealand Super Rugby Aotearoa 2021 squads. Pt. 1 The Blues | Pt. 2 The Chiefs | Pt. 3 The Crusaders | Pt. 4 The Highlanders | Pt. 5 The Hurricanes https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_Aotearoa_transfers2020-12-271h 30the.rugby.gods_podcastThe Hurricanes 2021 - Super RugbyJohn takes a look at the 2021 Hurricanes squad named in Dec. ‘20.https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_Aotearoa_transfers2020-12-2517 minthe.rugby.gods_podcastThe Highlanders 2021 - Super RugbyJohn takes a look at the 2021 Highlanders squad named in Dec. ‘20.https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_Aotearoa_transfers2020-12-2420 minthe.rugby.gods_podcastThe Crusaders 2021 - Super RugbyJohn takes a look at the 2021 Crusaders squad named in Dec. ‘20.https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_Aotearoa_transfers2020-12-2317 minthe.rugby.gods_podcastThe Chiefs 2021 - Super RugbyJohn takes a look at the 2021 Chiefs squad named in Dec. ‘20.https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_Aotearoa_transfers2020-12-2220 minthe.rugby.gods_podcastThe Blues 2021 - Super RugbyJohn takes a look at the 2021 Blues squad named in Dec. ‘20.https://en.wikipedia.org/wiki/List_of_2020%E2%80%9321_Super_Rugby_Aotearoa_transfers2020-12-2118 minthe.rugby.gods_podcastBledisloe Cup 2, Preview: 18 Oct.All Blacks v Australia, Auckland, 18 Oct. ‘20.A view from an Australian angle, a fairly brief check in.https://www.foxsports.com.au/rugby/bledisloe-cup/bledisloe-cup-ii-wallabies-vs-all-blacks-australia-v-new-zealand-teams-news-squads-injuries-kick-off-time/news-story/a1fd0cf3bb136636add7f3ca712bed13John’s pick: All Blacks +13 (second time lucky.)2020-10-1633 minthe.rugby.gods_podcastSR AU Rd.8-9, Review: 21 Aug. - 29 Aug. A North South All Blacks team.Recap of Super Rugby AU rounds 8 & 9. John’s North - South All Blacks team based on initial squads, mid Aug.2020-08-3145 min