Shows
Research Renaissance: Exploring the Future of Brain ScienceFrom Lived Experience to Life-Changing Innovation: How Praxis Reimagines Spinal Cord Injury SolutionsIn this powerful episode of Research Renaissance, Arushi Raina and John Tkaczyk from the Praxis Spinal Cord Institute pull back the curtain on what it really takes to innovate in spinal cord injury—and why the future of neurological care depends on integrating technology, science, and most importantly, lived experience.Rather than treating individuals as patients or passive recipients of care, Praxis centers their entire innovation pipeline around those living with spinal cord injury (SCI), involving them from ideation through market launch. Arushi shares how shifting from product “for” to product “with” the SCI community has accelerated meaningful...
2025-11-2559 minResearch Renaissance: Exploring the Future of Brain ScienceTransforming Communities Through Resilience Science with Dr. Wendy EllisIn this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Wendy Ellis, Assistant Professor of Global Health at George Washington University and Founding Director of the Center for Community Resilience. Together, they explore how resilience science and systems-level thinking can drive lasting change for communities impacted by adversity.Dr. Ellis shares her groundbreaking Pair of ACEs Framework, which connects adverse childhood experiences to adverse community environments, and discusses how this approach is helping policymakers, educators, and community leaders address root causes rather than symptoms. From innovative school-based partnerships in Portland to the development of...
2025-08-1947 minResearch Renaissance: Exploring the Future of Brain ScienceAtaxia, Advocacy, and Accelerating Research: Inside the National Ataxia FoundationWelcome back to Research Renaissance, presented by the Karen Toffler Charitable Trust. In this episode, host Deborah Westphal explores the cutting edge of rare disease research with special guests Andrew Rosen, CEO of the National Ataxia Foundation (NAF), and Dr. Lauren Moore, NAF’s Chief Scientific Officer.Together, they unpack how the NAF has evolved from a small support-focused nonprofit into a strategic, science-driven organization that’s advancing treatments and reshaping what’s possible for people living with ataxia—a rare, progressive neurological condition affecting movement and coordination.🔍 In this episode, we explore:
2025-08-0551 minResearch Renaissance: Exploring the Future of Brain ScienceUnlocking Parkinson’s Potential: The Brain-Immune Link with Dr. Adithya GopinathIn this groundbreaking episode of Research Renaissance, host Deborah Westphal reconnects with Dr. Adithya Gopinath, University of Florida, to explore a game-changing discovery in Parkinson’s research: a direct connection between dopamine neurons in the brain and the peripheral immune system, specifically the spleen.Dr. Gopinath shares how his lab’s findings could reshape the future of Parkinson’s diagnosis and treatment—potentially identifying the disease earlier and opening new therapeutic avenues using existing immune-modulating drugs. The episode also touches on surprising implications for conditions like addiction, ADHD, and even cancer.Key Topics Covered:The role...
2025-07-2935 minResearch Renaissance: Exploring the Future of Brain ScienceThe AI Cure: How Drug Repurposing is Saving LivesIn this episode of Research Renaissance, Deborah Westphal sits down with Dr. Grant Mitchell, co-founder and CEO of Every Cure — a nonprofit revolutionizing how we treat disease using artificial intelligence and drug repurposing.You’ll hear the incredible true story behind the organization’s founding: a rare disease, a near-death diagnosis, and the life-saving power of finding the right drug at the right time — one that was already FDA-approved but never intended for that disease.Dr. Mitchell unpacks how Every Cure is:Using AI to map connections between 4,000+ FDA-approved drugs and 20,000+ diseases.Tackling the “organizati...
2025-07-2251 minResearch Renaissance: Exploring the Future of Brain ScienceUnlocking Sex-Based Differences in Alzheimer’s Risk with Dr. Rachel BuckleyIn this powerful episode of Research Renaissance, host Deborah Westphal sits down with Dr. Rachel Buckley, Associate Professor of Neurology at Massachusetts General Hospital and Harvard Medical School. Together, they explore a growing body of research that challenges long-standing assumptions about sex differences in Alzheimer's disease.Dr. Buckley shares her unexpected journey from skepticism to advocacy in studying how biological sex and hormonal changes—particularly around menopause—can influence Alzheimer's risk, pathology, and progression. From PET scans to postmortem tissue studies, she unpacks what we now know about tau pathology in women, the role of hormone therapy, and...
2025-07-1548 minResearch Renaissance: Exploring the Future of Brain ScienceHow Regenerative Biology Could Help Treat Alzheimer’s with Dr. Prabesh BhattaraiIn this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Prabesh Bhattarai, Associate Research Scientist - The Taub Institute for Research on Alzheimer's Disease, the aging Brain, Columbia University Irving Medical Center and a 2024 Toffler Scholar.Dr. Bhattarai shares his groundbreaking work on regenerative biology and how understanding the remarkable ability of certain fish to regrow neurons could eventually lead to new treatments for neurodegenerative diseases like Alzheimer’s.They explore:🧠 How the fish geography can regenerate neurons lost to Alzheimer-like damage 🧬 The role of signaling molecules like IL-4 and BDNF...
2025-07-0845 minResearch Renaissance: Exploring the Future of Brain ScienceDecoding Alzheimer’s: Breakthroughs in Neural Recording using and Biostatistics & Machine LearningIn this exciting episode of Research Renaissance, host Deborah Westphal speaks with Dr. Ted Zwang, Assistant Professor of neurology at Massachusetts General Hospital and Harvard Medical School, Dr. Andrew Holbrook, Assistant Professor at UCLA and Jasen Zhang, PhD student in biostatistics in Holbrook’s lab. Together, they share how novel neural recording devices and advanced machine learning techniques are transforming the study of Alzheimer’s disease.Dr. Ted and Jasen discuss their collaborative project—funded by the Kavli Foundation, Cure Alzheimer’s Fund, and the Karen Toffler Charitable Trust—which captures how neurons change over time in Alzheimer’...
2025-07-0149 minResearch Renaissance: Exploring the Future of Brain ScienceHow Childhood Stress Shapes the Brain with Dr. Heather BrenhouseIn this fascinating episode of Research Renaissance, host Deborah Westphal sits down with Dr. Heather Brenhouse, professor of psychology and director of the Developmental Neuropsychobiology Lab at Northeastern University—and a 2024 Toffler Scholar. Together, they explore the deep connections between childhood adversity, brain development, and long-term mental health.Dr. Brenhouse discusses why early life stress impacts some individuals more than others, how adversity can alter the timing of puberty, and why understanding neurodevelopment is essential to preventing psychiatric disorders. They also delve into the biology of behavior, the role of immune cells in the brain, and how ev...
2025-06-2453 minResearch Renaissance: Exploring the Future of Brain ScienceEngineering the Brain—In the Lab and in SpaceIn this fascinating episode of Research Renaissance, host Deborah Westphall welcomes Dr. Alysson Muotri, a professor in the Departments of Pediatrics and Cellular & Molecular Medicine at the University of California, San Diego., for a deep dive into what makes the human brain unique—and how understanding that uniqueness might unlock new treatments for neurological disorders. From stem cell brain models grown in the lab to sending "mini-brains" into space, Dr. Muotri shares his bold, unconventional path to advancing neuroscience and personalized medicine.Dr. Muotri discusses his work creating 3D brain organoids to model human neurological development, including con...
2025-06-1740 minResearch Renaissance: Exploring the Future of Brain ScienceMicroscopic Conversations: How Organelles Communicate and What It Means for Curing Neurological DiseaseIn this episode of Research Renaissance, host Deborah Westphal welcomes Dr. Yvette Wong, Assistant Professor of Neurology at Northwestern University and 2024 Toffler Scholar, for a deep dive into the dynamic inner world of cells—and how her lab is uncovering new clues about neurodegenerative diseases by studying the microscopic interactions between organelles.Dr. Wong discusses how organelles like mitochondria and lysosomes don’t just function in isolation—they actually “talk” to each other at contact points within cells. These cellular conversations may hold the key to unlocking better understanding and treatments for conditions like ALS, Parkinson’s, and Huntingt...
2025-06-1045 minResearch Renaissance: Exploring the Future of Brain ScienceAging with Dignity: Advancing Equity, Access, and Brain HealthIn this compelling episode of Research Renaissance, host Deborah Westphal sits down with Sue Peschin, President and CEO of the Alliance for Aging Research, for a candid conversation about the intersection of science, policy, and aging. From Alzheimer’s drug coverage to the future of stem cell research, they unpack what it truly means to age with dignity—and how equity, access, and advocacy play a critical role.Sue shares her personal journey into aging research, her leadership transition at the Alliance, and the organization’s long-standing commitment to ensuring older adults receive fair and effective healthcare. They e...
2025-06-0353 minResearch Renaissance: Exploring the Future of Brain ScienceRewiring Brain Research—Why Networks Matter as Much as GenesIn this eye-opening episode of Research Renaissance, Dr. Rod Scott takes us on a journey through the emerging science of brain networks, complex adaptive systems, and why rethinking how we treat neurological conditions like epilepsy and autism might be the key to improving outcomes—especially in children.Dr. Scott explains why he views the brain not as a collection of isolated parts, but as a dynamic, self-organizing system. From his clinical experience to his cutting-edge lab work on neural firing patterns and cognitive behavior, he shares why focusing on repairing brain networks—rather than treating individual genes or s...
2025-05-2754 minResearch Renaissance: Exploring the Future of Brain ScienceInside the Mind of Brain Cancer: Modeling Glioblastoma with Dr. Frank FurnariIn this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Frank Furnari, professor of medicine at UC San Diego and co-director of the Brain Tumor Program at the Sanford Stem Cell Institute. Together, they explore one of the most aggressive and complex cancers known to medicine—glioblastoma—and the innovative tools his team is developing to study and treat it.🔬 Topics Covered:Why glioblastoma is so resistant to treatment—and what makes it uniqueThe role of tumor heterogeneity and how “chameleon-like” cancer cells adaptHow Dr. Furnari’s lab uses CRISPR-edited stem cells and “cancer avatars” t...
2025-05-2054 minResearch Renaissance: Exploring the Future of Brain ScienceInside the Neurodegeneration Puzzle: A Conversation with Jackson MaceIn this compelling episode of Research Renaissance, host Deborah Westphal sits down with Jackson Mace, a neuroscience PhD candidate at Johns Hopkins University and 2023 Toffler Scholar, to explore the cutting-edge research driving our understanding of neurodegenerative diseases—particularly multiple sclerosis (MS).Drawing from personal experience—his father’s MS diagnosis—and a deep academic curiosity, Jackson shares the winding path that led him from undergraduate lab work to a promising career in neuroimmunology. Together, they discuss:🧠 Why MS is more than just an autoimmune condition—and how it’s being reframed as a neurodegenerative disease 🧪 The expe...
2025-05-1352 minResearch Renaissance: Exploring the Future of Brain ScienceExploring the Role of Astrocytes and APOE in Alzheimer's Disease with Dr. Alberto Serrano-PozoIn this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Alberto Serrano-Pozo, Assistant Professor of Neurology at Harvard Medical School, staff neurologist at Massachusetts General Hospital, and a 2022 Toffler Scholar. Together, they explore Dr. Serrano-Pozo’s pioneering research into the role of glial cells—specifically astrocytes—and the APOE gene in the development and progression of Alzheimer’s disease.Dr. Serrano-Pozo discusses how astrocytes, long overlooked in favor of neurons, are now recognized as key players in maintaining brain health—and how their dysfunction may contribute to Alzheimer's pathology. The conversation also covers the complexiti...
2025-05-0642 minResearch Renaissance: Exploring the Future of Brain ScienceRewiring the Brain: Non-Invasive Neurotech & the Future of Treatment with Ana MaiquesIn this illuminating episode of Research Renaissance, host Deborah Westphal sits down with Ana Maiques, CEO and co-founder of Neuroelectrics, a groundbreaking company at the forefront of non-invasive brain stimulation technology. Together, they explore the intersection of neuroscience, entrepreneurship, and innovation, diving deep into how electrical brain stimulation is changing the future of treatment for neurological disorders like epilepsy, depression, and Alzheimer’s.Ana shares her unconventional journey into entrepreneurship, her commitment to ethical tech, and the long road to FDA approval. She also discusses the development of Neuroelectrics’ personalized brain therapies and the potential for at-home use...
2025-04-2948 minResearch Renaissance: Exploring the Future of Brain ScienceHow Philanthropy is Accelerating Alzheimer’s Breakthroughs with Meg SmithIn this episode of Research Renaissance, host Deborah Westphal is joined by Meg Smith, the Chief Executive Officer of Cure Alzheimer’s Fund. They dive deep into the innovative and high-impact research Cure Alzheimer’s Fund is supporting to prevent, slow, and ultimately cure Alzheimer’s disease. Meg shares her fascinating career journey from law and consulting to leading an organization that is revolutionizing brain disease research.Together, they discuss: ✅ The unique funding model of Cure Alzheimer’s Fund and why it accelerates research breakthroughs ✅ The biggest challenges in Alzheimer’s research and how philanthropic funding is filli...
2025-04-2255 minResearch Renaissance: Exploring the Future of Brain ScienceOxygen and Alzheimer’s: Dr. Nancy Ruiz on the Vascular ConnectionCan oxygen levels in the brain help explain Alzheimer’s disease? In this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Nancy E. Ruiz, a Harvard Medical School research fellow and 2023 Toffler Scholar, to explore a powerful yet underexamined piece of the Alzheimer’s puzzle: vascular dysfunction.Dr. Ruiz shares how her background in physics and biology led her to cutting-edge brain research using advanced imaging tools like two-photon phosphorescence lifetime imaging. Together, they dive into how oxygenation, blood flow, and lifestyle factors such as exercise and diet may hold the key to prevention — and wh...
2025-04-1541 minResearch Renaissance: Exploring the Future of Brain ScienceInnovation in Biotech & Leadership with Catharine SmithIn this episode of Research Renaissance, host Deborah Westphal sits down with Catharine Smith, Executive Director of the Termeer Foundation, to explore innovation in the biotech industry and the evolving role of leadership. They dive into how biotech leaders are shaping the future of healthcare, supporting emerging companies, and addressing rare diseases.Key Topics CoveredCatharine Smith’s Career Journey – From health services research to leading an influential foundation supporting biotech leaders.Biotech Leadership & Change Agents – What makes a great leader in the biotech space and how leadership is evolving.Henri Termeer’s Legacy – How the Te...
2025-04-0855 minResearch Renaissance: Exploring the Future of Brain ScienceExploring the Future of Science Policy with Dr. Carrie WolinetzIn this episode of Research Renaissance, host Deborah Westphal welcomes Dr. Carrie Wolinetz, a leading science and health policy expert. With an extensive background, including roles at the National Institutes of Health (NIH) and the White House Office of Science and Technology Policy, Dr. Wolinetz shares her insights on the evolving landscape of medical research funding, the role of science policy, and the critical intersection between government, private sector, and research institutions.From the historical foundations of federally funded science to the challenges posed by shifting political landscapes, Dr. Wolinetz offers a compelling perspective on the future...
2025-04-0259 minResearch Renaissance: Exploring the Future of Brain ScienceRevolutionizing ALS Drug Development with Dr. Kasper RoetWelcome to Research Renaissance, presented by the Karen Toffler Charitable Trust. In this episode, host Deborah Westphal sits down with Dr. Kasper Roet, CEO and co-founder of QurAlis, to explore the evolution of ALS drug development, the power of genetic insights, and the future of personalized medicine for neurodegenerative diseases.🔬 Episode Highlights:✔️ From Spinal Cord Injury to ALS – Dr. Roet’s journey from spinal cord injury research to ALS, and how genetic discoveries reshaped his focus.✔️ A New Era for Drug Development – The pivotal role of genomics, AI, and stem cell technol...
2025-03-2546 minResearch Renaissance: Exploring the Future of Brain ScienceThe Future of Research & Development with Dr. Melissa FlaggIn this thought-provoking episode of Research Renaissance, host Deborah Westphal welcomes Dr. Melissa Flagg, an advisor for the Andrew W. Marshall Foundation and a research fellow at the Acquisition Innovation Research Center. Dr. Flagg has had an extensive career spanning government, academia, and the private sector, including her role as Deputy Assistant Secretary of Defense for Research.Together, they explore the evolving landscape of research and development (R&D) in the U.S. and beyond. They discuss the history, funding models, and gaps in the system, as well as new opportunities to connect scientific research with real-world...
2025-03-181h 05Research Renaissance: Exploring the Future of Brain ScienceReversing Cognitive Decline: The Power of Lifestyle Medicine with Dr. Dean OrnishIn this enlightening episode of Research Renaissance, host Deborah Westphal sits down with Dr. Dean Ornish, founder of the Preventative Medicine Research Institute and a pioneer in lifestyle medicine. Dr. Ornish shares groundbreaking research on how lifestyle changes—including diet, exercise, stress management, and social connection—can not only prevent but even reverse chronic diseases, including early-stage Alzheimer’s disease.With nearly five decades of research, Dr. Ornish discusses how a whole-food, plant-based diet, moderate exercise, mindfulness practices, and social support can lead to remarkable improvements in cognition, heart disease, cancer, and even gene expression. This episode dives...
2025-03-1135 minResearch Renaissance: Exploring the Future of Brain ScienceThe Future of Alzheimer's Treatment: Philanthropy, Innovation, and Hope with Katie PizzoneIn this episode of Research Renaissance, host Deborah Westphal speaks with Katie Pizzone, Senior Director of Philanthropy at the Alzheimer’s Drug Discovery Foundation (ADDF). They discuss the critical role of philanthropy in advancing Alzheimer's research, the groundbreaking venture philanthropy model that ADDF employs, and the innovative treatments and diagnostics shaping the future of Alzheimer’s care.Katie shares her personal journey into philanthropy, her early experiences in healthcare fundraising, and how ADDF is working to accelerate translational science—bringing new diagnostics, treatments, and preventive solutions from research to real-world impact.Join us for a though...
2025-03-0444 min
Audioespai⚠️ Colmena IA y Transhumanismo Forzado - Karen Kingston y Dra. Ana Mihalcea 18-2-25 (Neurocontrol) - Episodio exclusivo para mecenasAgradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! DOGE, AI and Transhumanist Agenda – Conversation with Karen Kingston - TSS EP 49
18-2-25 https://anamihalceamdphd.substack.com/p/doge-ai-and-transhumanist-agenda
https://anamihalceamdphd.subtsack.com
https://karenkingston.substack.com
https://laquintacolumna.info
https://drdavidnixon.com
"En este episodio, Karen y yo hablamos sobre la reciente iniciativa DOGE y la preocupación que podría plantear la filtración de datos de seguridad social por parte de la IA. La agenda transhumanista consiste en recopilar la mayor cantidad posible de datos sobre cada individu...
2025-02-211h 13Research Renaissance: Exploring the Future of Brain ScienceExploring Cognitive Super Aging and Brain Science with Dr. Tamar GefenIn this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Tamar Gefen, an Associate Professor at the Mesulam Center for Cognitive Neurology and Alzheimer’s Disease at Northwestern University. Dr. Gefen, a 2023 Toffler Scholar, shares insights into her groundbreaking work on dementia syndromes and age-related cognitive disorders, including her fascinating research on cognitive "super agers."Key Discussion Points:Dr. Gefen’s personal journey to becoming a clinical neuropsychologist and her passion for studying the human brain.What it means to be a neuropsychologist and how it combines the study of brain stru...
2024-11-0553 minResearch Renaissance: Exploring the Future of Brain ScienceEmpowering Future Scientists: The SARE Program at Johns Hopkins UniversityGuests:Dr. Doug Robinson – Director of the Initiative for Careers in Science and Medicine, Johns Hopkins UniversityPamela Hamm – Director of the Summer Academic Research Experience (SARE)Eleana Parajon – Graduate Student and former SARE ScholarTemitope Adenaike – Current SARE ScholarAiden Houser – Current SARE ScholarSummary:In this episode, we dive into the transformative Summer Academic Research Experience (SARE) at Johns Hopkins University, a program designed to provide high school students from underrepresented communities the opportunity to gain hands-on research experience. Dr. Doug Robinson and Pamela Hamm share the program’s vision, while current students and alumni, including El...
2024-10-3152 minResearch Renaissance: Exploring the Future of Brain ScienceExploring the Future of Alzheimer's Research with Dr. Robert VassarIn this enlightening episode of Research Renaissance, Deborah Westphal speaks with Dr. Robert Vassar, a renowned neuroscientist and Director of the Mesulam Center for Cognitive Neurology and Alzheimer's Disease at Northwestern University. Dr. Vassar shares his personal journey into the field of Alzheimer’s research, the evolution of diagnostic tools, and the latest technological breakthroughs in the fight against neurodegenerative diseases.Key Topics Covered:Dr. Vassar’s Early Inspirations: Dr. Vassar shares his childhood fascination with science, the path that led him away from his dream of becoming an astronaut, and his ultimate decision to p...
2024-10-1557 minResearch Renaissance: Exploring the Future of Brain SciencePioneering Drug Delivery for Neurological Diseases with Afreen Allam In this compelling episode of Research Renaissance, host Deborah Westphal sits down with Afreen Allam, the CEO and founder of SiNON Nano Sciences and a 2023 Termeer Fellow. Afreen shares her journey from aspiring medical student to biotech entrepreneur, discussing her groundbreaking work in drug delivery for neurological diseases. The conversation delves into the challenges and triumphs of developing a platform that can cross the blood-brain barrier, offering hope for the treatment of diseases like Cancer, Alzheimer's, Parkinson's, and brain tumors.Key Discussion Points:SiNON Nano Sciences' Mission: Afreen explains the innovative approach her company takes to t...
2024-10-0846 minResearch Renaissance: Exploring the Future of Brain ScienceUnraveling the Senses: Dr. Douglas Storace on the Olfactory Bulb and Brain FunctionWelcome to the latest episode of Research Renaissance, presented by the Karen Toffler Charitable Trust. I’m your host, Deborah Westphal, and today, we have the pleasure of speaking with Dr. Douglas Storace, a neuroscientist and assistant professor at Florida State University. Dr. Storace is also a 2022 Toffler Scholar. Our discussion will delve into his research on the olfactory bulb, a crucial brain region responsible for processing smells, and its broader implications for understanding brain function and our bodies.Episode HighlightsDr. Storace's Journey to Neuroscience: Discover how a course on Se...
2024-10-011h 00Research Renaissance: Exploring the Future of Brain ScienceThe Power of Strategic Communication in Healthcare with Anne WoodburyIn this episode of Research Renaissance, host Deborah Westphal sits down with Anne Woodbury, the founder and CEO of Cura Strategies, a healthcare communication and public affairs agency. Together, they explore the crucial role of strategic communication in shaping healthcare policies and improving patient outcomes. Anne shares her journey from Capitol Hill to entrepreneurship, driven by a passion for transforming the healthcare system.Listeners will gain insights into how effective advocacy and communication strategies can drive change in healthcare, the importance of educating policymakers, and the growing awareness around mental health in the corporate world. Anne also...
2024-09-2454 minResearch Renaissance: Exploring the Future of Brain ScienceUnraveling ALS and Genetic Modifiers with Dr. Zhe ZhangIn this insightful episode of Research Renaissance, host Deborah Westphal engages in an enlightening conversation with Dr. Zhe Zhang, a research associate at Johns Hopkins and a 2021 Toffler Scholar. Dr. Zhang discusses her journey from aspiring to be a doctor to becoming a dedicated researcher focused on neurodegenerative diseases, particularly ALS. She shares her innovative work on establishing a platform to find genetic modifiers that can improve cell survival and slow the progression of ALS.Key Discussion Points:Introduction to Dr. Zhe Zhang:Background and inspiration for pursuing research in neurodegenerative diseases.Transition...
2024-09-1746 minResearch Renaissance: Exploring the Future of Brain ScienceNeurovascular Breakthroughs: Exploring Alzheimer's Treatments with Dr. Elisa CanepaIn this enlightening episode of Research Renaissance, host Deborah Westphal engages in a compelling conversation with Dr. Elisa Canepa, a neurobiologist and associate scientist from Temple University and a 2022 Toffler Scholar. Dr. Canepa shares her journey into neuroscience, driven by a fascination with the brain's complexity and its pivotal role in shaping our identity and cognitive functions. They delve into Dr. Canepa’s cutting-edge research on cerebral vascular dysfunction, particularly focusing on the potential of carbonic anhydrase inhibitors (CAIs) in treating Alzheimer's disease.Key Discussion Points:Introduction to Dr. Elisa Canepa:Background and in...
2024-09-1047 minResearch Renaissance: Exploring the Future of Brain ScienceNeurovascular Dysfunction and Neuroinflammation in Alzheimer's with Ashley CareyIn this episode of Research Renaissance, host Deborah Westphal engages in an enlightening conversation with Ashley Carey, a PhD candidate and 2023 Toffler Scholar at Temple University's Lewis Katz School of Medicine. Ashley's research focuses on the neurovascular dysfunction and neuroinflammation associated with Alzheimer's disease. She shares her journey from aspiring marine biologist to neuroscience researcher, highlighting the importance of cardiovascular health in preventing Alzheimer's.Guest Introduction: Ashley CareyAshley Carey is a PhD candidate and graduate research assistant in Dr. Silvia Fossati’s lab at Temple University. She is also a 2023 Toffler Sc...
2024-08-2740 minResearch Renaissance: Exploring the Future of Brain ScienceInnovative Collaborations in Biotech with Marissa Pettit JonesWelcome to Research Renaissance, presented by the Karen Toffler Charitable Trust. In this episode, host Deborah Westphal sits down with Marissa Pettit Jones, the Director of Business Development at Genentech and co-founder of Nucleate. They discuss Marissa's fascinating journey from biomedical engineering at Yale to her strategic role at Genentech, bridging the gap between science and business. Marissa shares insights into Genentech's innovative approaches, the dynamic pace of biotech advancements, and the critical role of Nucleate in fostering the next generation of biotech leaders.Marissa Pettit Jones is the Director of Business Development at Genentech, where she...
2024-08-2050 minResearch Renaissance: Exploring the Future of Brain ScienceThe Technology Advancing Alzheimer's Research with Dr. Sudeshna DasIn this episode of Research Renaissance, host Deborah Westphal dives into a fascinating conversation with Dr. Sudeshna Das, Associate Professor of Neurology at Mass General Hospital and Harvard Medical School. Dr. Das is a pioneer in the field of biomedical informatics and a 2022 Toffler Scholar. Her work focuses on developing tools for multi-scale data integration from molecular to clinical data and applying data science approaches to study neurodegenerative diseases, particularly Alzheimer’s disease.Guest Introduction: Dr. Sudeshna DasDr. Sudeshna Das is an Associate Professor of Neurology at Mass General Ho...
2024-08-1359 minResearch Renaissance: Exploring the Future of Brain ScienceThe Future of Technology and Healthcare with Ian KahnIn this episode of Research Renaissance, hosted by Deborah Westphal, we explore the future of technology and its impact on healthcare with guest Ian Kahn, a theoretical futurist. Ian discusses his role as a theoretical futurist, the importance of future readiness for organizations, and the evolution of technology in healthcare. He also shares insights into his work, including his series "The Futurist" and his books on emerging technologies.Ian Kahn is a renowned theoretical futurist helping organizations achieve future readiness. He hosts the series "The Futurist" on Amazon Prime and has written extensively on technology topics such...
2024-08-0651 minResearch Renaissance: Exploring the Future of Brain ScienceNavigating the Future of Alzheimer's Research with Dr. Bradley HymanWelcome to Research Renaissance presented by the Karen Toffler Charitable Trust. In this episode, host Deborah Westphal engages in a thought-provoking conversation with Dr. Bradley Hyman, Director of the Alzheimer's Disease Research Unit at Massachusetts General Hospital and John P. Pinney Jr. Professor of Neurology at Harvard Medical School. Dr. Hyman shares his insights on the evolving understanding of Alzheimer's disease, the impact of technological advancements on research, and the importance of multidisciplinary collaboration in tackling this complex condition.Dr. Bradley Hyman is a leading figure in Alzheimer's disease research, serving as the Director of the Alzheimer's...
2024-07-3053 minResearch Renaissance: Exploring the Future of Brain ScienceExploring Neurovirology with Dr. Maria NagelWelcome to Research Renaissance presented by the Karen Toffler Charitable Trust. In this episode, host Deborah Westphal dives into the fascinating world of neurovirology with Dr. Maria Nagel, a renowned professor, clinician, and scientist from the Department of Neurology at the University of Colorado. Dr. Nagel shares her insights on how viruses affect the nervous system, focusing on the varicella zoster virus (VZV) and its implications for diseases such as stroke and shingles.Dr. Maria Nagel is a distinguished neurovirologist specializing in the study of how viruses impact the brain, spinal cord, and peripheral nerves. With a...
2024-07-231h 01Research Renaissance: Exploring the Future of Brain ScienceUnlocking the Mysteries of Sleep with Dr. Alon AvidanWelcome to Research Renaissance, presented by the Karen Toffler Charitable Trust. Embark on a journey into the forefront of cutting-edge brain science as we feature insightful discussions with a diverse array of guests, from early career researchers pioneering groundbreaking science to influential voices in investment communities, policymaking, and research institutions. Together, we delve into neurological diseases, their causes, treatments, and the quest for cures.In this episode, we are joined by Dr. Alon Avidan, a distinguished Professor of Neurology at UCLA and the Director of the UCLA Sleep Disorders Center. Dr. Avidan, also a 2020 Toffler Scholar, is...
2024-07-161h 14Research Renaissance: Exploring the Future of Brain ScienceDeveloping AI Tools for Dementia Screening with Dr. Vijaya KolachalamaIn this episode of Research Renaissance, Dr. Vijaya Kolachalama, associate professor at Boston University and a Toffler Scholar, discusses his pioneering work in developing software frameworks that assist neurologists in dementia screening. This engaging discussion delves into how Dr. Kolachalama's team is integrating artificial intelligence and machine learning to improve the diagnostic process in neurology.Key Points Discussed:Creating Custom Methods for Science: Dr. Kolachalama explains his approach to creating specific methods tailored to the scientific challenges at hand rather than adapting science to fit pre-existing methods. This has led to...
2024-07-0951 minResearch Renaissance: Exploring the Future of Brain ScienceNavigating Health Policy and Public Advocacy with Dr. Marci NielsenWelcome to Research Renaissance, presented by the Karen Toffler Charitable Trust. Embark on a journey into the forefront of cutting-edge brain science as we feature insightful discussions with a diverse array of guests from early career researchers pioneering groundbreaking science to influential voices in investment communities, policymaking, and research institutions. Together, we delve into neurological diseases, their causes, treatments, and the quest for cures. In this episode, we are joined by Dr. Marci Nielsen, a prominent figure in healthcare policy and executive management. Dr. Nielsen shares her unique career journey from hard sciences to public he...
2024-07-021h 05Research Renaissance: Exploring the Future of Brain ScienceShedding Light on Alzheimer's with Sheila Griffith and Aaron SchulmanIn this episode of Research Renaissance, host Deborah Westphal delves into the crucial topic of Alzheimer's disease and the transformative efforts of the Alzheimer's Association. In recognition of June being Alzheimer's & Brain Awareness Month, Deborah’s guests are Sheila Griffith, Vice President of Programs and Services for the Alzheimer's Association National Capital Area Chapter and Aaron Schulman a volunteer community educator with the Alzheimer's Association. Sheila and Aaron bring their vast knowledge and personal insights into the challenges and advancements in Alzheimer's care.Key Discussion Points:Impact of Alzheimer's Disease:Sheila dis...
2024-06-271h 05Research Renaissance: Exploring the Future of Brain ScienceAI Meets Alzheimer's: A Journey with Dr. Andrew HolbrookIn this episode of Research Renaissance, host Deborah Westphal sits down with Dr. Andrew Holbrook, an Assistant Professor of Biostatistics at UCLA and a 2023 Toffler Scholar. Dr. Holbrook shares his fascinating journey from studying ancient languages and teaching in China to pioneering research in biostatistics and Alzheimer's disease. Together, they delve into the intersection of artificial intelligence, advanced algorithms, and brain science, exploring how these tools are revolutionizing our understanding of neurological diseases.Key Topics Discussed:Dr. Holbrook's Unique Journey: From studying an...
2024-06-2549 minResearch Renaissance: Exploring the Future of Brain ScienceNon-Invasive Stimulation for Alzheimer's with Dr. Alexandra TouroutoglouIn this insightful episode of Research Renaissance, Dr. Alexandra Touroutoglou shares her extensive work on brain imaging and non-invasive brain stimulation techniques to treat Alzheimer's disease and related dementias. Discover the cutting-edge technologies and methods being employed to understand and combat neurodegenerative diseases.Key Points Discussed:Academic Journey:Dr. Touroutoglou's transition from studying in Greece to pioneering neuroscience research at Harvard, highlighting the expansive possibilities in U.S. science.Non-Invasive Brain Stimulation:Exploration of transcranial magnetic stimulation (TMS) and its role in inducing neuroplasticity, potentially reversing the effects of brain...
2024-06-1846 minResearch Renaissance: Exploring the Future of Brain ScienceThe Complex Web of Protein Misfolding and Neurodegeneration with Dr. Joseph MazzulliIn this intriguing episode, Dr. Joseph Mazzulli, a 2022 Toffler Scholar, dives deep into the mechanisms of protein misfolding and amyloid formation, and their links to cell death in neurodegenerative diseases such as Parkinson's and Alzheimer's. Utilizing cutting-edge induced pluripotent stem cell models, Dr. Mazzulli explores how these proteins transition from a soluble to an insoluble state, leading to disease.Key Topics Covered:Understanding Protein Misfolding: An exploration of how proteins like amyloid and tau transition to harmful states in the brain.Innovative Research Techniques: Use of induced...
2024-06-111h 01Research Renaissance: Exploring the Future of Brain ScienceUnveiling the Genetics of Brain and Body with Dr. Valerie ArboledaIn this episode of Research Renaissance, presented by the Karen Toffler Charitable Trust, host Deborah Westphal explores the intricate world of genetic research with Dr. Valerie Arboleda. Dr. Arboleda, an associate professor at the David Geffen School of Medicine at UCLA and a 2023 Toffler Scholar, shares her insights into the genetic architecture of rare, monogenic diseases, and common complex diseases.Key Topics Covered:Understanding Genetic Diseases:Dr. Arboleda explains the difference between monogenic diseases, which can be traced to mutations in a single gene, and common complex diseases, which involve...
2024-06-041h 03Research Renaissance: Exploring the Future of Brain ScienceExploring Vascular Dysfunction in Alzheimer's with Dr. Silvia FossatiWelcome to Research Renaissance, presented by the Karen Toffler Charitable Trust. In this episode, host Deborah Westphal is joined by Dr. Silvia Fossati, Associate Professor of Neurosciences and Associate Director at the Alzheimer's Center at Temple University. Dr. Fossati, a 2021 Toffler Scholar, shares her insights on vascular dysfunction in the brain and its critical role in Alzheimer's disease and related conditions.Key Topics Covered:Academic Journey:Dr. Fossati's path from Tuscany to the forefront of Alzheimer's research in the United States, detailing her academic pursuits from Italy t...
2024-05-2859 minResearch Renaissance: Exploring the Future of Brain ScienceParkinson's and Lewy Body Dementia - A Deep Dive into Cellular Mysteries with Dr. Matt LavoieIn this episode, Dr. Matt Lavoie discusses his pioneering work on Parkinson's disease, exploring the intricate genetic factors and potential pathologies related to Lewy body dementia. As a 2022 Toffler Scholar, Dr. Lavoie shares his journey from early inspiration to major scientific contributions in neurology, offering unique insights into the complexities of neurodegenerative diseases and their impact globally.Key Topics Covered:Personal Journey into Research: Dr. Lavoie shares how his upbringing and academic experiences shaped his research path.Significance of the Fixel Endowed Chair: Understanding the impact and honor of his role...
2024-05-211h 03Research Renaissance: Exploring the Future of Brain ScienceUnraveling Alzheimer's: Molecular Insights with Dr. Jean-Pierre RoussarieIn this episode, Dr. Jean-Pierre Roussarie, Assistant Professor at Boston University School of Medicine and a 2023 Toffler Scholar, joins host Deborah Westphal to discuss his innovative research on Alzheimer's disease. Dr. Roussarie shares his journey from engineering to neurovirology and finally to his current focus on the molecular events that lead to neurodegeneration in Alzheimer's.Highlights:Academic Journey: From engineering to neurovirology at the Pasteur Institute, Dr. Roussarie explains his transition into Alzheimer's research, driven by a desire to tackle a major human health issue from a new perspective.Lab Focus: Insight into...
2024-05-1448 minResearch Renaissance: Exploring the Future of Brain ScienceBridging Innovations: From Research to Reality with Dr. Lydia McClureIn this episode, Dr. Lydia McClure, the newly appointed CEO of Research Bridge Partners, joins host Deborah Westphal to discuss the journey from laboratory discoveries to impactful startups. The conversation spans Lydia's personal career path, the focus of her organization on the middle of America, and the strategies used to identify and support groundbreaking researchers.Highlights:Lydia's Transition to CEO: Insights into Lydia’s recent appointment as CEO, her vision for Research Bridge Partners, and the mission to help faculty research evolve into successful companies.Lydia's Career Pathway:...
2024-05-0748 minResearch Renaissance: Exploring the Future of Brain ScienceExploring Primary Progressive Aphasia: A Conversation with Dr. Elena BarbieriIn this insightful episode of the Research Renaissance podcast, hosted by Deborah Westphal, Dr. Elena Barbereri, Research Assistant Professor at Northwestern University and a 2023 Toffler Scholar, sheds light on primary progressive aphasia (PPA). This rare neurological disorder progressively impairs the ability to speak and understand language while other cognitive functions remain relatively intact.Key Topics Discussed:Understanding Primary Progressive Aphasia (PPA): Dr. Barbereri discusses the characteristics of PPA, how it is diagnosed, and its differentiation from other conditions such as strokes or traumatic brain injuries. She emphasizes the progressive nature of...
2024-04-301h 01Research Renaissance: Exploring the Future of Brain ScienceThe Intricate Dance of the Brain and Immune System in Parkinson’s Disease with Dr. Adithya GopinathIn this episode, Dr. Adithya Gopinath shares his inspiring journey from a medical mystery patient to a pioneering researcher at the crossroads of neuroscience and immunology. The discussion centers on his current research exploring the interconnected roles of the central nervous system and the immune system in Parkinson's disease.Highlights:Personal Journey into Research: Dr. Gopinath's transition from a medical student to a researcher after a personal health crisis led to a passion for detailed scientific inquiry.Postdoctoral Life and Future...
2024-04-2345 minResearch Renaissance: Exploring the Future of Brain ScienceNavigating the Future of Brain Health and Innovation with Tom HubbardIn this episode of Research Renaissance, presented by the Karen Toffler Charitable Trust, host Deborah Westphal is joined by Tom Hubbard, Senior Vice President at the Network for Excellence in Health Innovation (NEHI). Together, they embark on an in-depth discussion about the intricate relationship between brain science and health policy, exploring the future of brain health, groundbreaking research, and the role of technology and policy in shaping the landscape of neurological disease treatment.Key Topics Covered:Introduction to NEHI: Tom Hubbard shares the origin, mission, and evolution of NEHI, highlighting its focus o...
2024-04-161h 05Research Renaissance: Exploring the Future of Brain ScienceBridging Cancer Research and Neurological Discoveries: A Deep Dive with Dr. Ignaty LeshchinerIn this compelling episode of Research Renaissance, host Deborah Westphal is joined by Dr. Ignaty Leshchiner, Associate Professor of Medicine at Boston University School of Medicine and a 2024 Toffler Scholar. Dr. Leshchiner, a pioneer in computational biology and cancer bioinformatics, explores the intricate relationship between cancer research and brain disease studies. His insights delve into groundbreaking methodologies for non-invasive cancer detection, the challenges in treating brain tumors, and the potential for early diagnosis of neurological diseases through advanced blood tests.Key Topics Discussed:The Intersection of Cancer Research and Neurology: Dr. Leshchiner's w...
2024-04-0958 minResearch Renaissance: Exploring the Future of Brain ScienceEngineering Insights: Revolutionizing Brain Imaging with Dr. Jeremias SulamWelcome to Episode 3 of "Research Renaissance," the podcast that dives into the evolving landscape of brain science, brought to you by the Karen Toffler Charitable Trust. Hosted by Deborah Westphal, this series is a lighthouse for those captivated by the intricacies of the brain, the boundary-pushing research unraveling its secrets, and the brilliant minds pioneering its future.In this enlightening episode, we connect with Dr. Jeremias Sulam from Johns Hopkins University, a luminary in the field of biomedical engineering and the esteemed recipient of the 2022 Toffler Scholar Award. ...
2024-04-0155 minResearch Renaissance: Exploring the Future of Brain ScienceNavigating the Future of Brain Science with Dr. Amy BernardIn this enlightening episode of Research Renaissance, we journey into the future of brain science with Dr. Amy Bernard, the Director of Life Science at the Kavli Foundation. Together, we explore the intersections of bioscience and technology, academia, and philanthropy, unraveling how these domains are shaping groundbreaking advancements in understanding and treating neurological diseases.Key Highlights:Dr. Amy Bernard's Background and Role: Dr. Bernard shares her extensive experience in research, innovation, and philanthropy. As the head of strategy and programs for neuroscience and nanoscience divisions at the Kavli Foundation, she plays a pivotal role in p...
2024-04-0158 minResearch Renaissance: Exploring the Future of Brain ScienceAdvancing Alzheimer's Research with Stem Cells and Genetics with Dr. Julia TCWWelcome to the Research Renaissance podcast, brought to you by the Karen Toffler Charitable Trust.In this episode, host Deborah Westphal is joined by Dr. Julia TCW, a leading figure in the field of brain science, focusing on the use of stem cells and genetics to combat Alzheimer's disease. Together, they delve into the current state and future of neurological disease research, discussing groundbreaking advancements and the quest for cures.Episode Highlights:Understanding Stem Cells: Dr. TCW breaks down the concept of stem cells, explaining their role in the...
2024-04-0155 minResearch Renaissance: Exploring the Future of Brain ScienceUnveiling the Neurological Frontier: In Conversation with Dr. Theodore ZwangWelcome to episode 2 "Research Renaissance," the podcast that delves into the enigmatic world of brain science, showcasing the brilliant minds and groundbreaking research that shape our understanding of the brain's potential. Hosted by Deborah Westphal and supported by the visionary insights of the Karen Toffler Charitable Trust, this series is a tribute to curiosity, innovation, and the relentless pursuit of knowledge.In this episode, we have the privilege of speaking with Dr. Theodore Zwang, a distinguished figure in the realm of neurology and an esteemed recipient of the 2023 Toffler Scholar A...
2024-04-0159 minResearch Renaissance: Exploring the Future of Brain ScienceFoundations of Futurism: Unveiling the Legacy of Alvin and Heidi TofflerWelcome to the inaugural episode of "Research Renaissance," a podcast where the frontiers of brain science unfold through engaging and insightful dialogues. Hosted by Deborah Westphal and brought to you by the Karen Toffler Charitable Trust, this series is a beacon for anyone intrigued by the complexities of the brain, the pioneering science probing its mysteries, and the innovative minds shaping its future.In this episode, we're introduced to the trust's vibrant legacy, rooted in the visionary minds of Alvin and Heidi Toffler. Our guests, Russ Gl...
2024-04-0156 min
Newt's WorldEpisode 621: Karen Toffler Charitable Trust – Advancing Medical ResearchThe Toffler’s were perhaps best-known for their innovative books, “Future Shock” and “The Third Wave.” Alvin and Heidi Toffler had a daughter, Karen, who died in 2000 at the age of 46 after more than a decade of suffering from Guillain-Barré Syndrome. After her death, the Toffler’s established the Karen Toffler Charitable Trust, to help fund neurological medical research breakthroughs. Newt’s guests are: Deborah Westphal, Executive Advisor of the Karen Toffler Charitable Trust, and two of the Trust’s Toffler Scholars and grant recipients; Adithya Gopinath, Postdoctoral Neuroscience, University of Florida and Vijaya Kolachalama, Associate Professor, Boston University. Learn more at htt...
2023-10-2243 min