Shows
microTalkA Career in the Time of Cholera: A Discussion with ASM Lifetime Achievement Award Winner John MekalanosDr. John Mekalanos (Harvard Medical School) has devoted his career to the study of bacterial pathogens, with a special emphasis to understanding Vibrio cholerae, the bacterium that causes the deadly disease cholera. And what an amazingly productive research path he has followed, from the discovery and characterization of the regulon that controls V. cholerae virulence, to the identification of the pilus that allows the bacteria to colonize the intestine, to the discovery of the bacteriophage that encodes the cholera toxin. His (relatively) recent discovery of the Type VI Secretion System and characterization of its role in inter-bacterial competition and ho...2022-07-2753 min
The Chain: Protein Engineering PodcastEpisode 37: Flashback Friday: COVID-19 Science-Sequence-Structure for Pandemic PreparednessThe Chain looks back to earlier this year when researchers virtually convened on the one-year anniversary of the first documented case of COVID-19 in the United States. This episode brings you a panel discussion from PepTalk Protein Science and Production Week, moderated by Karla Satchell, PhD, Professor of Microbiology and Co-Director of the Center for Structural Genomics of Infectious Diseases at Northwestern University. The panel discusses the role of data integration for the rapid R&D of therapeutics and vaccines, the immediate challenges in the new year – as the Delta variant spreads this summer in the United States -- an...2021-07-0921 min
The Chain: Protein Engineering PodcastEpisode 33: Tackling COVID-19 Drug Discovery with Structural GenomicsThe Center for Structural Genomics of Infectious Diseases at Northwestern University was prepared for COVID-19 long before the United States economy shut down. Now over a year since COVID-19 was first recorded in the U.S., co-director Dr. Karla Satchell speaks with The Chain about the role of structural genomics in preparing for disease outbreak and response.Karla Satchell, PhD, Professor, Microbiology; Principal Investigator and Co-Director, Center for Structural Genomics of Infectious Diseases, Northwestern UniversityDr. Karla Satchell is a Professor of Microbiology-Immunology at Northwestern University Feinberg School of Medicine since 2000. She is also...2021-05-1416 min
GenZ FrenZNorthwestern Immunology Prof. Answers Your COVID-19 QuestionsIn today’s episode we asked Nortwestern University microbiologist Dr. Karla Satchell some of our community’s most pressing questions about the COVID-19 virus. The episode covers a wide range of topic, from the science behind vaccines to what places to avoid as reopenings begin to when we can again be close to our friends. We hope you will listen and share this episode to spread science-based truth in the midst of all the misinformation in the world. More information about Karla Satchell’s research can be found here: https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=102852020-09-0416 min
Science VsCoronavirus: Dude, Where's My Vaccine?All through the pandemic, we’ve been waiting for a possible silver bullet: a vaccine. How soon could we actually get one? To find out, we talk to microbiologist and immunologist Professor Karla Satchell, immunologist Dr. Kathryn Stephenson, Pfizer executive Mike McDermott, and Ian Haydon, who’s participating in a vaccine clinical trial.Here’s a link to our transcript: https://bit.ly/3egWFrcThis episode was produced by Wendy Zukerman, with help from Michelle Dang, Sinduja Srinivasan, Laura Morris, Meg Driscoll, Rose Rimler, Meryl Horn, and Mathilde Urfalino. We’re...2020-06-1932 minScience VsCoronavirus: Will Chloroquine Save Us?President Trump says an anti-malarial drug could be a “gift from god” for treating Covid-19. Does it really work? And is it dangerous? We talk to toxicologist Professor Daniel Brooks, infectious disease specialist Dr. Matthew Pullen, and microbiologist Professor Karla Satchell. Also: VAMPIRE BATS!We’ve set up a voicemail to collect all of your questions about Coronavirus. Or if you’re a healthcare worker with a personal story you want to share, please call (774) 481-1238 and leave us a message.Here’s a link to our transcript: https://bit.ly/2xu4ER8...2020-03-2727 min
microTalkVibri-Oh-No! - “Flesh Eating” Vibrios with Karla SatchellSummer brings warm beach weather, and with it come gruesome news reports of “flesh eating disease” that people catch from the ocean. Vibrio vulnificus is a marine bacterium that prefers warmer seawater, and it can infect wounds and cause necrotizing fasciitis, also known as “flesh eating disease”, that can rapidly turn into a fatal infection. Dr. Karla Satchell is a professor at the Feinberg School of Medicine at Northwestern University who studies the toxins made by V. vulnificus and other Vibrios that allow them to cause disease. Satchell talks about how people get infected with V. vulni...2019-07-221h 02