Shows
This Week in CardiologyNov 14 2025 This Week in CardiologyListener feedback on the PISCES trial, AHA news (including a big PCSK9i trial), beta-blockers post MI, LAAC, and post-AF ablation OAC use are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback Why I Believe Fish Oil's Big CV Benefit in Dialysis Patients https://www.medscape.com/viewarticle/why-i-believe-fish-oils-big-cv-benefit-dialysis-patients-2025a1000uzg PISCES trial https://www.nejm.org/doi/full/10.1056/NEJMoa2513032 I...
2025-11-1436 minThis Week in CardiologyNov 07, 2025 This Week in CardiologyListener feedback on non-culprit PCI in STEMI, a major cardiac result in patients on hemodialysis, news on GLP-1 agonists, a dubious stroke trial, and an AHA preview are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback Meta-analysis of MI as a surrogate https://pubmed.ncbi.nlm.nih.gov/34694318/ Compare Acute Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1701067 DANAMI-3–PRIMULTI 10.1016/S0140-6736(15)60648-1 Exte...
2025-11-0732 minThis Week in CardiologyMay 16 2025 This Week in CardiologyThe BedMed trial of nighttime BP meds, SURMOUNT-5, Troponin URL, gene tests in patients with no disease, and guideline-directed medical therapy for HF are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Timing of BP Meds – The BedMed RCT MAPEC https://doi.org/10.3109/07420528.2010.510230 Hygia https://doi.org/10.1093/eurheartj/ehz754 Turgeon et al https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.121.16501 TIME trial https://doi.org/10.1016/S0140-6736(22)01786-X...
2025-05-1628 minThis Week in CardiologyMar 28 2025 This Week in CardiologyStopping oral anticoagulation after AF ablation, the core problem with paradoxes like the smoker's paradox, chronic total occlusion PCI, and an ACC/EHRA preview are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Oral Anticoagulation after Successful AF Ablation Iwawakie et al https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831851 OCEAN protocol paper https://doi.org/10.1016/j.ahj.2017.12.007 II Smoker's Paradox Presch et al https://www.j...
2025-03-2828 minThis Week in CardiologyFeb 21 2025 This Week in CardiologyBlanking period after AF ablation, periprocedural MI after PCI in non-STEMI, predicting AF after ischemic stroke, and the proper standards for mitral valve repair in primary mitral regurgitation are the topics John Mandrola, MD, discusses in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I AF blanking period CIRCA DOSE Research letter https://www.ahajournals.org/doi/10.1161/CIRCEP.124.013232 Circa-Dose https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.042622 COMPARE CRYO https://doi.org/10.1016/j.jacep.2024.03.021 Mohanty et...
2025-02-2128 minThis Week in CardiologyDec 20 2024 This Week in CardiologyListener feedback, multiple studies in AF ablation, a DANISH trial substudy of ICDs in NICM, and more data on eye complications of GLP-1 agonists are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. CCTA Feedback Foy meta-analysis https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243 DANCAVAS https://www.nejm.org/doi/full/10.1056/NEJMoa2208681 II. Listener Feedback on my negative take of the OPTION Trial.
2024-12-2036 minThis Week in CardiologyDec 13 2024 This Week in CardiologyUS doc's pay, the ticagrelor controversy and new RCTs, clopidogrel beats ASA, holding antiplatelets for non-cardiac surgery, and Prof Cleland and ASA dogma are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. US Healthcare Mandrola's Top 10 Stories in 2024 https://www.medscape.com/viewarticle/mandrolas-top-10-stories-2024-2024a1000mxe?_gl=1*dcvmkh*_gcl_au*MTgzOTY2ODQ0Ni4xNzI5MjU4NjUz CMS Proposal II. Ticagrelor Controversy
2024-12-1329 minThis Week in CardiologyNov 15 2024 This Week in CardiologyTirzepatide, AF screening, and an AHA preview, including VT ablation, LAAC at the time of AF ablation, BP targets, and GLP1 agonists in HF are the topics John Mandrola, MD, covers in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Tirzepatide SURMOUNT 1 – Three-year results https://www.nejm.org/doi/full/10.1056/NEJMoa2410819 II. AF Screening GUARD AF https://www.jacc.org/doi/10.1016/j.jacc.2024.08.019 LOOP 10.1016/S0140-6736(21)01698-6 STROKE STOP 10.1016/S0140-6736(21)01637-8...
2024-11-1528 min
EHRA Cardio TalkBest evidence in EP With David Duncker, Hannover Heart Rhythm Center, Hannover - Germany, Stefan Simovic, Clinical Center Kragujevac & Faculty of Medical Sciences, University of Kragujevac - Serbia, and John Mandrola, Baptist Health, Louisville - USA. This episode strives for the best evidence together with John Mandrola.
2024-11-0425 minThis Week in CardiologyAug 30 2024 This Week in CardiologyFrom ESC: post-MI beta blockers, a new therapy for ATTR-CM, holding RASi before non-cardiac surgery, good news in HFpEF, and an ESC preview are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. ABYSS ABYSS trial https://www.nejm.org/doi/full/10.1056/NEJMoa2404204 REDUCE AMI https://www.nejm.org/doi/full/10.1056/NEJMoa2401479 II. ATTR -CM HELIOS B Positive Top Line Results for Vutrisiran in Cardiac A...
2024-08-3026 min
Hipótese Nula#10 Maio 24 - Andexanet Alfa | aGLP1 na Nefropatia DiabéticaTEMA 1: Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage - ANNEXA-I | NEJM --> Comentário no blogue --> Justin Morgenstern no First10EM --> Anand Swaminathan no RebelEM --> John Mandrola no Sensible Medicine TEMA 2: Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes - FLOW | NEJM --> Comentário no blogue --> John Mandrola no TWIC Recomendações culturais: Filme "Hit Man" ("Assassino Profissional") do Richard Linklater (Mariana) Álbum "Subida Infinita" dos Capitão Fausto (B
2024-06-0436 min
Hipótese Nula#9 Abril 2024 - Beta-bloqueantes e iSGLT2 no pos-EAMTEMA 1: Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction - REDUCE-AMI | NEJM --> Comentário no blogue --> John Mandrola sobre prova prévia no Sensible Medicine --> John Mandrola sobre REDUCE-AMI no Medscape TEMA 2: Empagliflozin after Acute Myocardial Infarction | EMPACT-MI --> Comentário no blogue --> John Mandrola no Medscape Recomendações culturais: Série "Succession" da HBO (Bernardo) Livro "The Anxious Generation" do Jonathan Haidt
2024-05-1737 minThis Week in CardiologyApr 05 2024 This Week in CardiologyStatins and diabetes, AAD in patients with heart disease, tricuspid valve interventions, and an ACC preview are the topics John Mandrola, MD, discusses in this week's podcast.This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Statins and Diabetes Meta-analysis in Lancet-Diabetes https://doi.org/10.1016/S2213-8587(24)00040-8 Editorial https://doi.org/10.1016/S2213-8587(24)00059-7 NEJM Paper on Gene Variants and DM https://www.nejm.org/doi/full/10.1056/nejmoa1604304 JAMA Paper on Gene Variants and DM https://jamanetwork.c...
2024-04-0526 minThis Week in CardiologyFeb 02 2024 This Week in CardiologyFDA approves PFA for AF ablation, flawed comparisons of TEER vs MV surgery and PCI vs CABG, and cardiologists struggling with board exams are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. PFA FDA Okays Boston Scientific PFA System for Paroxysmal AF https://www.medscape.com/viewarticle/fda-okays-boston-scientific-pfa-system-paroxysmal-af-2024a1000275 Pulsed-Field Ablation for AF: The Promise and the Reality h...
2024-02-0227 min
Patient PulseTreatment of Atrial Fibrillation with Dr John MandrolaLet us know your thoughts. We would love to hear from you.Dr. Thomas Nero interviews Dr. John Mandrola on his approach to treating atrial fibrillation. In addition to a nuts and bolts approach they discuss how to assess risk and shared decision making.
2023-12-2612 min
Future Pulse CardiologyAtrial Fibrillation and Clinical Trials with Dr John MandrolaWe would love to hear your thoughts on the episodes!Dr Mandrola discusses recent trail data with Dr. Thomas Nero including the results from Artesia, NOAH Afnet 6, Frail AF, Azalea and Oceanic-AF. They also discuss Left Atrial Appendage Occlusion and utility of wearable devices. Finally, a shout out to Dr. Andre Foy and his work on multi-morbidity and its role in clinical trial interpretation.
2023-12-2648 minThis Week in CardiologyNov 10 2023 This Week in CardiologyRenal denervation, a potential deadly decision in the ED, GLP-1 agonists, and an AHA preview are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Renal Denervation FDA OKs Paradise Renal Denervation System for Hypertension https://www.medscape.com/viewarticle/998237 - Company Press Release https://www.recormedical.com/recor-medical-and-otsuka-medical-devices-announce-first-fda-approved-renal-denervation-system-for-the-treatment-of-hypertension/ - Six-month Meta-analysis of RDN Studies https://www.ahajournals.org/d...
2023-11-1024 min
Parallax by Ankur KalraEP 101: Translating Evidence, Innovations & Value for Patients with Dr John MandrolaIn this week's episode of Parallax, Dr. Ankur Kalra welcomes Dr. John Mandrola, a cardiac electrophysiologist practicing in Louisville and the host of the popular podcast "This Week in Cardiology" and co-author of Sensible Medicine, among other forums.
In this insightful episode, we delve into Dr. Mandrola's career journey. He discusses how the beginnings of his career during a period of significant innovations and the reversal of expert opinions profoundly influenced his perspective on medicine, leading to a more conservative stance. Dr. Kalra then invites Dr. Mandrola to share the motivations that drive his work as a medical journalist and...
2023-09-2547 minThis Week in CardiologyAug 25 2023 This Week in CardiologyGLP-1 agonists in HFpEF, DOACs for subclinical AF, renal denervation, and the matter of remaining in the profession are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Obesity and HFpEF GLP-1 Agonists in HFpEF With Obesity: Are We There Yet? https://www.medscape.com/viewarticle/993980 Wegovy Scores HFpEF Benefits in People With Obesity https://www.medscape.com/viewarticle/995844 - Semaglutide in...
2023-08-2530 min
The Bob Harrington ShowAI and Machine Learning in Healthcare for the Clueless: No Coding RequiredRobert Harrington, MD and Jenine John, a cardiologist and machine learning research fellow discuss what you need to know about AI and ML in healthcare and where to find some helpful resources. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit: https://www.medscape.com/author/bob-harrington 'One Brave Idea' Recipient on Predicting Who Will Develop CAD https://www.medscape.com/viewarticle/874536 Multinational Federated Learning Approach to Train ECG and Echocardiogram Models for Hypertrophic Cardiomyopathy Detection https://doi.org/10.1161/circulationaha.121.058696
2023-04-1022 min
The Groves ConnectionJohn Mandrola, MD - The Neutral Martian (S3E3)Today I have the pleasure of speaking with Dr. John Mandrola.
Nominally, Dr. Mandrola is a cardiac electrophysiologist, specializing in heart rhythm disorders, but there’s much more to his story. He’s currently the chief cardiology correspondent for Medscape, writes two regular columns, and records a weekly podcast. This guy is everywhere, and for good reason. As a leader in medical thought, his unique take on modern healthcare is perhaps best summed up in his 2019 paper with Dr. Adam Cifu — The Case for Being a Medical Conservative.
“Medical conservatives are not nihilists. We apprec...
2023-03-0743 minThis Week in CardiologyMar 3 2023 This Week in CardiologyRenal denervation, AF ablation, omecamtiv mecarbil, and an ACC Preview are the topics discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. AF Ablation - Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures https://www.jacc.org/doi/10.1016/j.jacc.2022.11.060 II. Renal Denervation Consistent BP Cut With Renal Denervation: More on RADIANCE https://www.medscape.com/viewarticle/989006 ...
2023-03-0324 minThis Week in CardiologyDec 16, 2022 This Week in Cardiology PodcastBP control over the long term, omecamtiv mecarbil, incentives and Goodhart's law, and open science are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Long-Term BP Control - Final SPRINT Data Confirm Lower BP Is Better https://www.medscape.com/viewarticle/951572 - Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control https://jamanetwork.com/journals/jamacardiology/fullarticle/2797064 - Let's Not SPRINT to Judgment About New...
2022-12-1627 minThis Week in CardiologyDec 9, 2022 This Week in Cardiology PodcastNudges, statins, AI, less-is-more in the ICU, myocarditis, exercise as medicine, and December in the hospital are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Nudges and Statin Prescribing EHR Alerts to Both Doc and Patient May Boost Statin Prescribing https://www.medscape.com/viewarticle/984944 Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing https://jamanetwork.com/j...
2022-12-0922 minThis Week in CardiologyNov 4, 2022 This Week in Cardiology PodcastAF conversion in the ED, HRT, a shining example of evidence-based medicine and less-is-more, multimorbidity, and what's coming at AHA are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. AF Conversion - IV Potassium and Magnesium an Acute Treatment for AF? https://www.medscape.com/viewarticle/983137 - Association of Intravenous Potassium and Magnesium Administration With Spontaneous Conversion of Atrial Fibrillation and Atrial Flutter in the Emergency Department https...
2022-11-0421 minThis Week in CardiologyAug 26, 2022 This Week in Cardiology PodcastEarly rhythm control in AF, treating coronary artery disease before transcatheter aortic valve implantation, and an ESC 2022 preview are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Early Rhythm Control - Early AF Rhythm-Control Advantage Climbs With Comorbidity Burden: EAST-AFNET4 https://www.medscape.com/viewarticle/979627 - Early Rhythm Control in Patients With Atrial Fibrillation and High Comorbidity Burden https://www.ahajournals.org/doi/suppl/10.1161/CIRCULATIONAHA.122.060274
2022-08-2626 minThis Week in CardiologyApr 1, 2022 This Week in Cardiology PodcastCoronary CTA, semaglutide, coronary artery calcium, exercise, and an ACC and EHRA preview are the topics discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I – Coronary CTA Feedback - Coronary Computed Tomography Angiography vs Functional Stress Testing for Patients With Suspected Coronary Artery Disease https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243 II – Semaglutide - FDA Okays Semaglutide Higher Dose, 2 mg/Week, for Type 2 Diabetes https://www.medscape.com/viewarticle/971156
2022-04-0120 minThis Week in CardiologyDec 17, 2021 This Week in Cardiology PodcastPFO closure, trans-mitral procedures, yoga as therapy, and a year-end-review are the topics John Mandrola, MD, covers in this week's podcast. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I – PFO Closure - Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke https://jamanetwork.com/journals/jama/fullarticle/2787115 - Patent Foramen Ovale Closure—Harnessing Clinical Trial Evidence to Inform Individualized Treatment Decisions https://jamanetwork.com/journals/jama/fullarticle/2787132 - Personalized evid...
2021-12-1720 minThis Week in CardiologyNov 12, 2021 This Week in Cardiology PodcastLeft atrial appendage closure vs DOACs, TAVR vs SAVR, renal denervation, and an AHA 2021 preview are the topics John Mandrola, MD, discusses in this week's podcast. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I - LAAC - PRAGUE-17: LAA Closure Holds Up Against DOACs Out to 4 Years https://www.medscape.com/viewarticle/962608 - LAAO vs DOAC: PRAGUE-17 Falls Short https://www.medscape.com/viewarticle/933641 - Left Atrial Appendage Closure versus Non-Warfarin Oral Anticoagulation in Atrial Fibrillation: 4-Year Outcomes of PRAGUE-17 https://www.jacc.org...
2021-11-1223 min
The External Medicine PodcastMedical Conservatism, Myocarditis, and Physician Advocacy with John Mandrola, MDThis conversation with Dr. John Mandrola was recorded on July 11th, 2021. In this interview, Daniel Belkin and Mitch Belkin speak with Dr. Mandrola about a 2019 article he co-authored entitled The Case for Being a Medical Conservative. They discuss concerns about vaccine-induced myocarditis in children, vaccine mandates, and whether the AMA and other physician organizations should take sides on controversial political issues. Who is John Mandrola?Dr. John Mandrola is a practicing cardiac electrophysiologist and a regular columnist for theheart.org on Medscape. He hosts the fantastic “This Week in Cardiology” podcast and is a blo...
2021-07-2553 minThis Week in CardiologyMay 14, 2021 This Week in Cardiology PodcastThe upcoming ACC meeting, polypharmacy, finerenone, and ethics and professionalism are the topics covered by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic ACC Preview: ACC.21 Looks to Repeat Success Despite Pandemic Headwinds https://www.medscape.com/viewarticle/950836 - Level and Prevalence of Spin in Published Cardiovascular Randomized Clinical Trial Reports With Statistically Nonsignificant Primary Outcomes: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/31050775/ Polypharmacy Hypertension Worsened by Commonly Used Prescription Meds https://www.medscape.com/viewarticle/950724 Finerenone Finerenone Scores...
2021-05-1417 min
Plenary Session - inactive due to federal service3.21 Affirmative Action with Leah Litman, Cost Implications with Dr. DeMartino, & Dr. John MandrolaFirst up this week we interview constitutional law scholar Leah Litman, an Assistant Professor of Law at the University of Michigan, on Dr. Norman Wang and the intricacies of the laws on affirmative action. Next, we talk with Dr. Patrick DeMartino, a pediatric hematology/oncology fellow at Oregon Health & Science University, on his new paper out now in JAMA Internal Medicine: "Potential Cost Implications for All US Food and Drug Administration Oncology Drug Approvals in 2018". Finally, we sit down with Dr. John Mandrola for an in-depth discussion on the intersection of medicine, politics, and advocacy.
Cost Implications: doi.org/10.1001/jamainternmed.2020.5921
...
2020-11-143h 04Plenary Session - inactive due to federal service3.21 Affirmative Action with Leah Litman, Cost Implications with Dr. DeMartino, & Dr. John MandrolaFirst up this week we interview constitutional law scholar Leah Litman, an Assistant Professor of Law at the University of Michigan, on Dr. Norman Wang and the intricacies of the laws on affirmative action. Next, we talk with Dr. Patrick DeMartino, a pediatric hematology/oncology fellow at Oregon Health & Science University, on his new paper out now in JAMA Internal Medicine: "Potential Cost Implications for All US Food and Drug Administration Oncology Drug Approvals in 2018". Finally, we sit down with Dr. John Mandrola for an in-depth discussion on the intersection of medicine, politics, and advocacy.
Cost Implications: doi.org/10.1001/jamainternmed.2020.5921
...
2020-11-143h 04
Questioning Medicine145. Rosiglitazone, Dr. Mandrola, Ethics committee, GlaxoSmithKline, and the mafiaFinance ethics committee, big pharma with deep pockets, mafia like arrangements, and a patient with a 40% increase risk of ischemia myocardial events have in common?I will say todays podcast was inspired by a tweet, yes a tweet from Dr. john Mandrola and he said “I am embarrassed to have not (really) known the details of the rosiglitazone affair. Teaching this to learners has to be 10x more valuable than the krebs cycle. My gosh – talk about lessons to learn. We have to promote more skeptical priors’ He attached a link to a paper titled
2020-09-1333 minThis Week in CardiologySep 11, 2020 This Week in Cardiology PodcastCOVID, icosapent ethyl, sudden death, and antiplatelet choices in the elderly are topics John Mandrola, MD, discusses in this week's podcast.
2020-09-1118 min
The Accad and Koka ReportJohn Mandrola: Why Doctoring and Politics Shouldn’t MixDr. John Mandrola returns to the show to discuss why doctoring and politics shouldn’t mix and how he got into hot water on Twitter for holding that unacceptable view.
Dr. Mandrola is an electrophysiologist in Louisville, Kentucky. He is is cardiology editor on Medscape where he writes a regular column and produces a weekly podcast.
SHOW NOTES
John Mandrola, MD: Twitter and WebsiteJohn Mandrola: “Doctoring and Activism“Sally Satel: “The Hypocritical Oath“Mandrola et al: The Case for Being a Medical Conservative (in the American Journal of Medicine)
2020-09-1100 minThis Week in CardiologySep 4, 2020 This Week in Cardiology PodcastCOVID, trust in the FDA, and ESC Recap: Part 1 are the topics John Mandrola, MD, covers in this week's podcast.
2020-09-0420 min
Active TownsThe Joy of Riding Again w/ Lennard ZinnIn this episode, we have a wide-ranging discussion with Lennard Zinn, a Boulder, Colorado-based former elite-level bike racer, journalist, author, and custom bike builder. Lennard is probably best known for his frequent technical journalistic contributions on VeloNews and his incredibly popular books published by VeloPress on bike maintenance and repair, Zinn and the Art of Mountain Bike Maintenance and Zinn and the Art of Road Bike Maintenance.He's also a co-author, along with Chris Case and Dr. John Mandrola, of The Haywire Heart: How too much exercise can kill you, and what you can do to protect...
2020-09-041h 03This Week in CardiologyAug 28, 2020 This Week in Cardiology PodcastCOVID and the heart, convalescent plasma, PCI in the VA system, and the upcoming ESC meeting are discussed by John Mandrola, MD, in this week's podcast.
2020-08-2818 minThis Week in CardiologyAug 21, 2020 This Week in Cardiology PodcastCOVID, diversity, clinical research, the S-ICD, and ECGs are the topics discussed by John Mandrola, MD in this week's podcast.
2020-08-2116 minThis Week in CardiologyAug 14, 2020 This Week in Cardiology PodcastCOVID, obesity, heart failure, Impella, and fitness are the topics John Mandrola, MD, discusses in this week's podcast.
2020-08-1418 minThis Week in CardiologyJul 31, 2020 This Week in Cardiology PodcastCOVID, cardiac effects of COVID, AF ablation safety, and SGLT2i are the topics discussed by Dr John Mandrola in this week's podcast.
2020-07-3116 min
All About FitnessDr. John Mandrola - Cardiophysiologist and co-author of the Haywire HeartYes, exercise is good for us, but is there such a thing as too much exercise? Where does exercise makes the transition from an activity that promotes health to one that could be fatal? On this episode, Dr. John Mandrola, a cardiologist, amateur cyclist and co-author of the Haywire Heart, is able to share his insights both as an athlete and a medical expert on cardiac health for a fun, insightful and educational conversation about how your heart adapts to exercise and when too much might be too much. Learn more about your ad choices. Visit megaphone...
2020-07-2643 minThis Week in CardiologyJul 24, 2020 This Week in Cardiology PodcastCOVID vaccines, T-cells, ICDs, Watchman, and two features are the topics John Mandrola, MD, discusses in this week's podcast.
2020-07-2417 minThis Week in CardiologyJul 17, 2020 This Week in Cardiology PodcastCOVID, the EXCEL trial, AF ablation, and pacemaker techniques are the topics discussed by John Mandrola, MD in this week's podcast.
2020-07-1720 minThis Week in CardiologyJul 10, 2020 This Week in Cardiology PodcastCOVID, sacubitril/valsartan, left atrial appendage occlusion, and statins are the topics Dr John Mandrola discusses in this week's podcast.
2020-07-1019 minThis Week in CardiologyJune 26, 2020 This Week in Cardiology PodcastCOVID, science communication breakthrough, tricuspid valve disease, and AF ablation are the topics discussed by John Mandrola, MD, in this week's podcast.
2020-06-2617 minThis Week in CardiologyJun 19, 2020 This Week in Cardiology PodcastCOVID19, corticosteroids, CAC, SGLT2i, and vericiguat are the topics discussed by Dr. John Mandrola in this week's podcast.
2020-06-1918 minThis Week in CardiologyJun 12, 2020 This Week in Cardiology PodcastISCHEMIA, COVID-19 statistics, and racial justice are discussed by Dr John Mandrola in this week's podcast.
2020-06-1219 minThis Week in CardiologyJun 5, 2020 This Week in Cardiology PodcastCOVID19, protests, Impella, Excel, Bayesian statistics, and journal retractions are discussed by John Mandrola, MD, in this week's podcast.
2020-06-0518 minThis Week in CardiologyMay 29, 2020 This Week in Cardiology PodcastCOVID-19, nursing homes, evidence based medicine, hydroxychloroquine and VT, and remdesivir are the topics discussed by John Mandrola, MD, in this week's podcast.
2020-05-2918 minThis Week in CardiologyMay 22, 2020 This Week in Cardiology PodcastCOVID-19, medical education, collider bias, Watchman, and VT are the topics John Mandrola, MD, discusses in this week's podcast.
2020-05-2217 minThis Week in CardiologyMay 15, 2020 This Week in Cardiology PodcastCOVID-19 stats, anticoagulation in acute COVID-19 illness, ICD trials, and left bundle branch pacing are the topics discussed by John Mandrola, MD, in this week's podcast.
2020-05-1521 minThis Week in CardiologyMay 8, 2020 This Week in Cardiology PodcastCOVID-19, the angiotensin receptor blocker, TAVR, and acute stroke care are covered by John Mandrola, MD, in this week's podcast.
2020-05-0817 minThis Week in CardiologyMay 1, 2020 This Week in Cardiology PodcastCOVID-19, social distancing, ECG monitoring, thrombosis, and TAVR are discussed by John Mandrola, MD, in this week's podcast.
2020-05-0115 minThis Week in CardiologyApr 24, 2020 This Week in Cardiology PodcastNew epidemiologic studies, pitfalls of testing, and treatments for COVID-19 are the topics discussed by John Mandrola, MD in this week's podcast.
2020-04-2418 minThis Week in CardiologyApr 17, 2020 This Week in Cardiology PodcastThe COVID-19 crisis—epidemiology, viral therapeutics, pulmonary management, and coagulopathy—is the topic discussed by John Mandrola, MD in this week's podcast.
2020-04-1718 minThis Week in CardiologyApr 10, 2020 This Week in Cardiology PodcastThe COVID-19 crisis—epidemiology, ventilation protocols, telemedicine, and humanity in these dark days—are the topics discussed by John Mandrola, MD in this week's podcast.
2020-04-1018 minThis Week in CardiologyApr 3, 2020 This Week in Cardiology PodcastThe COVID19 crisis—heroes, viral spread, betrayals, and intolerance of ideas—are discussed by John Mandrola, MD in this week's podcast.
2020-04-0317 minThis Week in CardiologyMar 27, 2020 This Week in Cardiology PodcastThe COVID-19 crisis—ethics, hydroxychloroquine, and angiotensin drugs—are among the topics discussed by John Mandrola, MD in this week's podcast.
2020-03-2713 minThis Week in CardiologyMarch 20, 2020 This Week in Cardiology PodcastThe newest developments in COVID-19 are discussed by John Mandrola, MD, in this week's podcast.
2020-03-2010 min
Freely Filtered, a NephJC PodcastGadolinium in CKD 4 and 5 meta-analysisJust the dudes gathered to talk about the JAMA Internal Medicine Meta Analysis on Gadolinium in CKD stage 4 and 5.Risk of Nephrogenic Systemic Fibrosis in Patients With Stage 4 or 5 Chronic Kidney Disease Receiving a Group II Gadolinium-Based Contrast AgentA Systematic Review and Meta-analysis.Summary on NephJCCast:Joel TopfSwapnil HiremathMatt SparksShow Notes:Swap has a disclosure!He was an author on the Canadian Association of Radiology guidelines on use of Gad in CKD.Grobner’s original pa...
2020-03-1059 minThis Week in CardiologyMar 6, 2020 This Week in Cardiology PodcastCOVID-19, left main coronary diseases, and cascades are the topics covered by Dr John Mandrola in this week's podcast.
2020-03-0616 minThis Week in CardiologyFeb 28, 2020 This Week in Cardiology PodcastSocial media tension, bempedoic acid, hopeful news from CMS, and carotid interventions are the topics discussed by Dr John Mandrola in this week's podcast.
2020-02-2819 minThis Week in CardiologyFeb 21, 2020 This Week in Cardiology PodcastMore fuel piled onto the EXCEL trial controversy, GI bleeds in AF, medical education, and revascularization procedures are covered by Dr John Mandrola in this week's podcast.
2020-02-2118 minThis Week in CardiologyFeb 14, 2020 This Week in CardiologyCardiac stents, cardio-oncology, VT ablation, acute AF are the topics discussed by Dr John Mandrola in this week's podcast.
2020-02-1420 minThis Week in CardiologyFeb 7, 2020 This Week in Cardiology PodcastThe NEJM retraction, TAVR 5-year results, ICD selection, long QT reversals, and lung cancer screening are the topics discussed by John Mandrola, MD in this week's podcast.
2020-02-0719 minThis Week in CardiologyJan 24, 2020 This Week in Cardiology PodcastExecutive physicals, coconut fat, leadless pacemakers, coils, and independent nurse practitioners and physician assistants are the topics discussed by Dr. John Mandrola in this week's podcast.
2020-01-2417 minThis Week in CardiologyJan 17, 2020 This Week in Cardiology PodcastEXCEL, amyloid cardiomyopathy, drug prices, palliative care in cardiology, and gender bias are the topics covered by Dr John Mandrola in this week's podcast.
2020-01-1715 minThis Week in CardiologyJan 10, 2020 This Week in Cardiology PodcastThe Excel trial, peripartum cardiomyopathy, marathoning, hot-spotting, and leadership in innovation are the topics discussed by Dr. John Mandrola in this week's podcast.
2020-01-1019 minThis Week in CardiologyJan 3, 2020 This Week in Cardiology PodcastThe EXCEL debate, the NOBLE trial, alcohol and AF, cardiac devices, and hospital consolidation are the topics covered by John Mandrola, MD, in this week's podcast.
2020-01-0319 minThis Week in CardiologyDec 20, 2019 This Week in CardiologyA risk score for device infection, conflicts of interest, the Fragility Index, rhythm vs rate control for AF in HFpEF, and year-end highlights are discussed by John Mandrola, MD, in this week's podcast.
2019-12-2019 minThis Week in CardiologyDec 13, 2019 This Week in CardiologyThe EXCEL trial controversy, and Dr John Mandrola's experience with vernakalant at FDA are the topics covered in this week's podcast.
2019-12-1319 minThis Week in CardiologyDec 6, 2019 This Week in Cardiology PodcastVernakalent, CV death in cancer patients, dapagliflozin, and sacubitril/valsartan are the topics Dr. John Mandrola discusses in this week's podcast.
2019-12-0520 minThis Week in CardiologyNov 22, 2019 This Week in Cardiology PodcastHighlights from the 2019 AHA meeting are analyzed by Dr John Mandrola in this week's podcast.
2019-11-2224 minThis Week in CardiologyNov 15, 2019 This Week in Cardiology PodcastInterruption of oral anticoagulation, marijuana and stroke, ORBITA substudy, ISCHEMIA medical therapy targets, and more on AHA are the topics discussed by Dr. John Mandrola in this week's podcast.
2019-11-1518 minThis Week in CardiologyNov 8, 2019 This Week in Cardiology PodcastWords that harm, statins, thyroid replacement, and the ISCHEMIA trial are the topics discussed by Dr John Mandrola in this week's podcast.
2019-11-0822 minThis Week in CardiologyNov 1, 2019 This Week in Cardiology PodcastMortality after AF ablation, cardiac rehab programs, hypertrophic cardiomyopathy, and clinician wellness are the topics Dr. John Mandrola discusses in this week's podcast.
2019-11-0119 minThis Week in CardiologyOct 25, 2019 This Week in Cardiology PodcastAF after TAVR, opioids after cardiac devices, hypertension in black adults, and post-cardiac surgery AF are the topics Dr John Mandrola discusses in this week's podcast.
2019-10-2517 minThis Week in CardiologyOct 18, 2019 This Week in Cardiology PodcastThe Nobel Prize, more on the EXCEL trial, the costs of cardiac tests, familial hypercholesterolemia, and burnout are the topics discussed by Dr John Mandrola in this week's podcast.
2019-10-1819 minThis Week in CardiologyOct 11 2019 This Week in CardiologyLeft main PCI vs CABG trials and TAVR vs SAVR—in this week's podcast, Dr John Mandrola takes a deeper dive.
2019-10-1127 minThis Week in CardiologySep 27, 2019 This Week in Cardiology PodcastSocial effects of medicine, SGLT2 inhibitors, CIED infections, equity in cardiology, and post-PCI anti-thrombotic therapy are the topics discussed by Dr John Mandrola in this week's podcast.
2019-09-2716 min
Plenary Session - inactive due to federal service1.07 Adjuvant Sunitinib in RCC, future of EBM with Dr. John MandrolaIn this episode we discuss the USA FDA's recent approval of sunitinib as the adjuvant treatment for patients with resected renal cell carcinoma who are at high risk of relapse. We also interview cardiologist Dr. John Mandrola on new directions forward for evidence-based medicine.
2018-09-111h 02Plenary Session - inactive due to federal service1.07 Adjuvant Sunitinib in RCC, future of EBM with Dr. John MandrolaIn this episode we discuss the USA FDA's recent approval of sunitinib as the adjuvant treatment for patients with resected renal cell carcinoma who are at high risk of relapse. We also interview cardiologist Dr. John Mandrola on new directions forward for evidence-based medicine.
2018-09-111h 02The Accad and Koka Report12. John Mandrola: The Case for "Less-Is-More"Anish Koka and Michel Accad explore the “less-is-more” movement with Dr. John Mandrola, one of its most articulate and popular champions. They discuss the problem of practices that have no scientific justification and the conundrum of out-of-control costs. What is the best way to curtail unwarranted therapies? Should there be more top down regulations or is it possible that more health care freedom will lead to less utilization?
The Accad and Koka Report podcast, hosted by two MDs, focuses on free-market approaches to medicine and health. Subscribe on iTunes, Android, Stitcher, or via RSS.
2018-06-2400 min
Absorb An Riveting Full Audiobook And Elevate Your Mindset.The Haywire Heart by Chris Case, John Mandrola MD, Lennard ZinnPlease visithttps://thebookvoice.com/podcasts/2/audible/60742to listen full audiobooks.
Title: The Haywire Heart
Author: Chris Case, John Mandrola MD, Lennard Zinn
Narrator: Steve Menasche
Format: mp3
Length: 8 hrs and 27 mins
Release date: 06-19-18
Ratings: 4.5 out of 5 stars, 63 ratings
Genres: Cycling
Publisher's Summary:
The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing, The Haywire Heart presents the evidence that going too hard or too long can damage your heart forever. You'll find what to watch out...
2018-06-198h 27
Explore Into A Heart-Pounding Full Audiobook During Your Workout.The Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart by John Mandrola MD, Lennard Zinn, Chris CasePlease visithttps://thebookvoice.com/podcasts/1/audiobook/339627to listen full audiobooks.
Title: The Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart
Author: John Mandrola MD, Lennard Zinn, Chris Case
Narrator: Steve Menasche
Format: Unabridged Audiobook
Length: 8 hours 28 minutes
Release date: June 19, 2018
Ratings: Ratings of Book: 5 of Total 1
Genres: Fitness, Diet & Nutrition
Publisher's Summary:
Too much exercise can kill you. The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing...
2018-06-198h 28Experience An Powerful Full Audiobook And Elevate Your Mindset.The Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart by John Mandrola MD, Lennard Zinn, Chris CasePlease visithttps://thebookvoice.com/podcasts/1/audiobook/339627to listen full audiobooks.
Title: The Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart
Author: John Mandrola MD, Lennard Zinn, Chris Case
Narrator: Steve Menasche
Format: Unabridged Audiobook
Length: 8 hours 28 minutes
Release date: June 19, 2018
Ratings: Ratings of Book: 5 of Total 1
Genres: Medicine & Naturopathy
Publisher's Summary:
Too much exercise can kill you. The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing, The...
2018-06-198h 28Get Lost In Your Day With A Game-Changing Full Audiobook.The Haywire Heart by Chris Case, John Mandrola MD, Lennard ZinnPlease visithttps://thebookvoice.com/podcasts/2/audible/60742to listen full audiobooks.
Title: The Haywire Heart
Author: Chris Case, John Mandrola MD, Lennard Zinn
Narrator: Steve Menasche
Format: mp3
Length: 8 hrs and 27 mins
Release date: 06-19-18
Ratings: 4.5 out of 5 stars, 63 ratings
Genres: Cycling
Publisher's Summary:
The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing, The Haywire Heart presents the evidence that going too hard or too long can damage your heart forever. You'll find what to watch out...
2018-06-198h 27Get Latest Full Audiobooks in Health & Wellness, Medicine & NaturopathyThe Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart by John Mandrola MD, Lennard Zinn, Chris CasePlease visithttps://thebookvoice.com/podcasts/1/audiobook/339627to listen full audiobooks.
Title: The Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart
Author: John Mandrola MD, Lennard Zinn, Chris Case
Narrator: Steve Menasche
Format: Unabridged Audiobook
Length: 8 hours 28 minutes
Release date: June 19, 2018
Ratings: Ratings of Book: 5 of Total 1
Genres: Medicine & Naturopathy
Publisher's Summary:
Too much exercise can kill you. The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing, The...
2018-06-198h 28Download New Full Audiobooks in Health & Wellness, Fitness, Diet & NutritionThe Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart by John Mandrola MD, Lennard Zinn, Chris CasePlease visithttps://thebookvoice.com/podcasts/1/audiobook/339627to listen full audiobooks.
Title: The Haywire Heart: How Too Much Exercise Can Kill You, and What You Can Do to Protect Your Heart
Author: John Mandrola MD, Lennard Zinn, Chris Case
Narrator: Steve Menasche
Format: Unabridged Audiobook
Length: 8 hours 28 minutes
Release date: June 19, 2018
Ratings: Ratings of Book: 5 of Total 1
Genres: Fitness, Diet & Nutrition
Publisher's Summary:
Too much exercise can kill you. The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing...
2018-06-198h 28
Fast TalkToo much of a good thing? Heart arrhythmias in endurance athletesIn this episode we take a deep dive into a subject that Case knows well, and that our guest, Lennard Zinn, has lived for the last five years: Heart arrhythmias in endurance athletes. Chris and Lennard, along with Dr. John Mandrola, wrote a book entitled “The Haywire Heart” that details how and why long-term endurance exercise could cause a variety of heart arrhythmias. We’ll also hear from Jeremy Powers, who dealt with his own heart arrhythmia this past cyclocross season. Learn more about your ad choices. Visit megaphone.fm/adchoices
2018-03-161h 21
Heart PodcastAn ACC preview show with Medscape’s Dr John MandrolaIn this episode of the Heart podcast, Digital Media Editor Dr James Rudd is joined by cardiologist and EP specialist Dr John Mandrola from Louisville, Kentucky. John is also Medscape's chief cardiology correspondent. They discuss the eye-catching late-breaking trials from the upcoming ACC meeting in Orlando.
Please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2
John Mandrola's podcast at Medscape - https://www.medscape.com/index/list_10295_0
John Mandrola's columns at Medscape - https://www.medscape.com/index/section_10325_0 and https://www.medscape.com/index/section_10382_0
2018-03-0517 min
Heart podcastAn ACC preview show with Medscape's Dr John MandrolaIn this episode of the Heart podcast, Digital Media Editor Dr James Rudd is joined by cardiologist and EP specialist Dr John Mandrola from Louisville, Kentucky. John is also Medscape's chief cardiology correspondent. They discuss the eye-catching late-breaking trials from the upcoming ACC meeting in Orlando.
Please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2
John Mandrola's podcast at Medscape - https://www.medscape.com/index/list_10295_0
John Mandrola's columns at Medscape - https://www.medscape.com/index/section_10325_0 and https://www.medscape.com/index/section_10382_0
2018-03-0517 min
Run to the Top Podcast | The Ultimate Guide to RunningHow to Protect Your Heart for the Miles Ahead with Dr. John Mandrola, Lennard Zinn and Chris Case The Haywire Heart with Dr. John Mandrola, Lennard Zinn, and Chris Case It’s been said that if a little does a good job, then a lot is even better and too much is probably just right. However, evidence indicates that too much exercise, like that experienced by years of endurance sports, can lead to what is known as “athlete’s heart” - a host of conditions easy for physicians to misdiagnose. In this episode, we are joined by Dr. John Mandrola, Lennard Zinn, and Chris Case, the co-authors of The Haywire Heart. Their book details nu...
2017-03-291h 12RunnersConnect Run to the Top PodcastHow to Protect Your Heart for the Miles Ahead with Dr. John Mandrola, Lennard Zinn and Chris Case The Haywire Heart with Dr. John Mandrola, Lennard Zinn, and Chris Case It’s been said that if a little does a good job, then a lot is even better and too much is probably just right. However, evidence indicates that too much exercise, like that experienced by years of endurance sports, can lead to what is known as “athlete’s heart” - a host of conditions easy for physicians to misdiagnose. In this episode, we are joined by Dr. John Mandrola, Lennard Zinn, and Chris Case, the co-authors of The Haywire Heart. Their book details nu...
2017-03-291h 12
Nourish Balance ThriveThe Cyclist's Guide to Obstacle RacingI sit too much. When I’m not sitting at my desk, I’m sitting on my bike. As a mountain biker, I stand more than some cyclists, but still. The ways in which I move my body are predictable and very repetitive. I almost never move from side to side, and I expend vast amounts of energy spinning small circles with my feet. Have humans evolved to move like this? I doubt it. I know that if I’m not careful, I start to develop niggling lower back pain and piriformis syndrome. Obstacle racing then, or at lea...
2016-04-2842 min
Cycling Time Trial Podcast#70. Dr. John Mandrola-Heart Rhythm Doctor-Cycling and your Heart, Pt. 2Part 2 of our Special Series, Cycling and your Heart. Dr. John Mandrola is a heart rhythm doctor (Cardiac Electrophysiologist) in Louisville, KY. I would encourage you to visit Dr. John’s (as he is known) website at drjohnm.org. There is a lot of good information there about all things medical. We welcome Dr. John Mandrola.
Follow Dr. Mandrola on twitter... @drjohnm
Follow me @markflorence11
Contact me at cyclingtimetrialpodcast@gmail.com
2016-04-0225 minScreening for Medical Disease with Dr. John MandrolaThis weekend on YOUR HEALTH® Adam and guest cohost Dr. Jessica Anderson will be talking with Dr. John Mandrola, Electrophysiologist and Columnist for Medscape about Screening for Medical Disease. Please tune in! The show will air: WCHL 97.9FM • Saturday, February 27th at 9 a.m. and 5 p.m. • Sunday, February 28th at 9 a.m. and 5 p.m. • Monday, […]
2016-02-2539 min
The Runners Round TableRRT 124: Health and Running HeadlinesJoin Dr. Dave (nevernotrunning.com and @nevernotrunning) and friends for a discussion of recent media coverage of health and running related topics. Some of the items up for discussion include:Do statins (cholesterol drugs) degrade muscle performance? (NYTimes)Sudden deaths during races, should I be worried? (NY Daily News)Do you need to take a multivitamin if you eat a healthy diet? (NYTimes, SweatScience)Five tests that can save your life (?) (Men's Health) Planned call time: Thursday April 26th at 6P Eastern.Joining Dr. Dave will be:Sarb Johal (@sarb), who blogs at http://nzbound...
2012-04-2700 min