MScEpi - Podcast Details

Shows

Evidence-Based GI: An ACG Publication and PodcastAGA-ACG Clinical Practice Guideline on Chronic Idiopathic Constipation Treatments: Parsing Benefits and RisksJacqueline Gaulin and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “AGA-ACG Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation,” by Chang L, Chey WD, Imdad A, et al. Am J Gastroenterol [2023; 118: 936-54].2023-06-1410 min

Evidence-Based GI: An ACG Publication and PodcastScreening Colonoscopy in the Elderly Population-Is Less Better?Philip Okafor, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Frequency of Use and Outcomes in Individuals Older than 75 Years,” by El Halabi J, Burke CA, Hariri E, et al. JAMA Internal Medicine [2023; 183: 513-19].2023-06-1411 min

Evidence-Based GI: An ACG Publication and PodcastFree Online Program Improves Adenoma Detection Rate and Decreases Post-Colonoscopy Colorectal CancerJeffrey Lee, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Impact of a Scalable Training Program on the Quality of Colonoscopy Performance and Risk of Post-Colonoscopy Colorectal Cancer,” by Corley DA, Jensen CD, Lee JK, et al. Gastrointest Endosc [2023; In Press].2023-06-1409 min

Evidence-Based GI: An ACG Publication and PodcastProphylactic Antibiotics Do Not Improve Mortality in Severe Alcoholic Hepatitis Treated with CorticosteroidsEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discusses “Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis,” by Louvet A, Labreuche J, Dao T, et al. [JAMA 2023; 329 (18): 1558-66].2023-05-1710 min

Evidence-Based GI: An ACG Publication and PodcastOver-the-Scope Clips Decrease Non-Variceal Upper GI Bleeding vs Standard Endoscopic Treatment… In the Right PatientJennifer Kolb, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Comparison of Over-the-Scope Clips to Standard Endoscopic Treatment as the Initial Treatment in Patients With Bleeding From a Nonvariceal Upper Gastrointestinal Cause: A Randomized Controlled Trial,” by Lau JYW, Li R, Tan C et al. Ann Intern Med [2023 Apr;176(4):455-462].2023-05-1711 min

Evidence-Based GI: An ACG Publication and PodcastDisposable Elevator Caps for Duodenoscopes Decrease Persistent Bacterial Contamination Without Hindering Technical ERCP Performance: The ICECAP TrialShria Kumar, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Effect of Disposable Elevator Cap Duodenoscopes on Persistent Microbial Contamination and Technical Performance of Endoscopic Retrograde Cholangiopancreatography: The ICECAP Randomized Clinical Trial,” by Forbes N, Elmunzer BJ, Allain T, et al. JAMA Intern Med [2023;183(3):191-200].2023-05-1707 min

Evidence-Based GI: An ACG Publication and PodcastVibrating Capsules for Chronic Constipation: The New Non-Pharmacologic ApproachEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discussesEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discusses “Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation,” by Rao S, Quigley EMM, Chey WD, et al. Gastroenterology [2023].2023-04-1909 min

Evidence-Based GI: An ACG Publication and PodcastICYMI: Can we prevent hepatic decompensation? Most likely, with nonselective beta blockers.Sonali Paul, MD, MS, and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Beta blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomized, double-blind, placebo-controlled, multicenter trial,” by Villanueva C, Albillos A, Genesca J, et al. Lancet [2019, Apr 20;393(10181):1597-1608]. Erratum in: Lancet [2019 Jun 22;393(10190):2492].2023-04-1909 min

Evidence-Based GI: An ACG Publication and PodcastICYMI: Vedolizumab Is Superior to Adalimumab for Clinical Remission and Endoscopic Improvement of Ulcerative Colitis-The VARSITY RCTJessica Allegretti, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis,” by Sands BE, Peyrin-Biroulet L, Loftus EV Jr, Danese S, Colombel JF, Toruner M, Jonaitis L, Abhyankar B, Chen J, Rogers R, Lirio RA, Bornstein JD, Schreiber S. N Engl J Med [2019 Sep 26;381(13):1215-1226].2023-04-1911 min

Evidence-Based GI: An ACG Publication and PodcastWhat are the Causes of Post-colonoscopy Colorectal Cancer?Jeffrey Lee, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Post-Colonoscopy Colorectal Cancer Etiologies in a Large Integrated US Health Care Setting,” by Leung LJ, Lee JK, Merchant SA, Jensen CD, Alam A, Corley DA. Gastroenterology [2022. PMID: 36462551].2023-03-1513 min

Evidence-Based GI: An ACG Publication and PodcastTumor-based screening for Lynch Syndrome: Check Every Colorectal CancerSwati G. Patel, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “A Canadian Provincial Screening Program for Lynch Syndrome,” by Stone JK, Winter R, Khan D, Rothenmund H, Klein J, Chodirker B, Wightman R, Kim CA, Nugent Z, Singh H. American Journal of Gastroenterology [2023;118:345-53].2023-03-1514 min

Evidence-Based GI: An ACG Publication and Podcast10-Year Intervals After Normal Screening Colonoscopy: It’s Not Too Long with High-Quality ColonoscopyPhilip Okafor MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Prevalence of Colorectal Neoplasia 10 or More Years After A Negative Screening Colonoscopy in 120,000 Repeated Screening Colonoscopies,” by Heisser T, Kretschmann J, Hagen B, et al. JAMA Intern Med [2023; 183: 183-90].2023-03-1507 min

Evidence-Based GI: An ACG Publication and PodcastCold Snare Decreases Post-Polypectomy Bleeding vs Hot Snare for Small PolypsEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discusses “Cold Versus Hot Snare Polypectomy for Small Colorectal Polyps: A Pragmatic Randomized Controlled Trial,” by Chang LC, Chang CY, Chen CY, et al. Ann Intern Med [2023; In Press].2023-03-1510 min

Evidence-Based GI: An ACG Publication and PodcastDirect-Acting Antiviral Therapy for Hepatitis C Virus Decreases All-Cause Mortality and Decompensated Cirrhosis: Treat (Virtually) EveryoneEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “Association of Direct-Acting Antiviral Therapy with Liver and Nonliver Complications and Long-term Mortality in Patients with Chronic Hepatitis C,” by Ogawa E, Chien N, Kam L, et al. JAMA Internal Medicine [2023; 183: 97-105].2023-02-2206 min

Evidence-Based GI: An ACG Publication and PodcastEarly Colonoscopy for Acute Lower GI Bleeding Usually Is Not the AnswerShria Kumar, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Timing of Colonoscopy in Acute Lower GI Bleeding: A Multicenter Retrospective Cohort Study,” by Shiratori Y, Ishii N, Tomonori A, et al. Gastrointest Endosc [2023; 97: 89-99].2023-02-2210 min

Evidence-Based GI: An ACG Publication and PodcastEndoscopic Sleeve Gastroplasty Is Effective for Patients with Obesity Who MERIT InterventionJennifer Kolb, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Endoscopic Sleeve Gastroplasty for Treatment of Class 1 and 2 Obesity (MERIT), a Prospective, Multicentre, Randomised Trial,” by Dayyeh BKA, Bazerbachi F, Vargas EJ, et al. Lancet [2022; 400: 441-51].2023-02-2210 min

Evidence-Based GI: An ACG Publication and PodcastDupilumab, an IgG4 Monoclonal Antibody, for Eosinophilic Esophagitis: Revising the Treatment ParadigmAfrin Kamal, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis,” by Dellon ES, Rothenber MH, Collins I, et al. N Engl J Med [2022; 387: 2317-30].2023-02-2215 min

Evidence-Based GI: An ACG Publication and PodcastICYMI: Is Terlipressin for the Treatment of Hepato-Renal Syndrome Ready for Primetime: Results of the CONFIRM TrialEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG and Sonali Paul, MD, MS discuss “Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome,” by Wong F, Pappas SC, Curry KR, et al. N Engl J Med [2021; 384: 818-28].2023-02-0308 min

Evidence-Based GI: An ACG Publication and PodcastWhen It’s Not Acid Reflux: Managing PPI-Resistant GERD Patients Based on Bravo ResultsEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG and Kristle Lee Lynch, MD discuss “Optimal Wireless Reflux Monitoring Metrics to Predict Discontinuation of Proton Pump Inhibitor Therapy,” by Yadlapati R, Gyawali CP, Masihi M, et al. Am J Gastroenterol [2022 Oct 1;117(10):1573-1582].2023-01-2510 min

Evidence-Based GI: An ACG Publication and PodcastRisankizumab, an Interleukin-23 Inhibitor, for Moderate-Severe Crohn’s Disease: Advancing Care Beyond Anti-TNF TherapyJessica Allegretti, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Risankizumab as maintenance therapy for moderately to severely active Crohn's disease: results from the multicentre, randomised, double-blind, placebo-controlled, withdrawal phase 3 FORTIFY maintenance trial,” by Ferrante M, Panaccione R, Baert F, et al. Lancet [2022 May 28;399(10340):2031-2046].2023-01-2510 min

Evidence-Based GI: An ACG Publication and PodcastRisankizumab, an Interleukin-23 Inhibitor, for Moderate-Severe Crohn’s Disease: Advancing Care Beyond Anti-TNF TherapyBharati Kochar, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Risankizumab as Induction Therapy for Crohn’s Disease: Results from the Phase 3 ADVANCE and MOTIVATE Induction Trials,” by D’Haens G, Panaccione R, Baert F, et al. Lancet [2022; 399: 2015-30].2023-01-2517 min

Evidence-Based GI: An ACG Publication and PodcastOzanimod, a Selective Selective Sphingosine-1-Phosphatase Receptor Modulator, for Moderate-Severe Ulcerative Colitis: Re-Thinking the Top-Down Treatment Algorithm for UCOriana Damas, MD and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi discuss “Ozanimod for Induction and Maintenance of Ulcerative Colitis,” by Sandborn WJ, Feagan BG, D’Haens G, et al. N Engl J Med [2021; 385: 1280-91].2022-12-1317 min

Evidence-Based GI: An ACG Publication and PodcastContinuing Anti-TNF Agents past 24 Weeks of Pregnancy Associated with Fewer IBD Relapses with No Increase in Adverse Fetal OutcomesAhmad Abu-Heija, MBBS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Benefits and Risks Associated with Continuation of Anti-Tumor Necrosis Factor After 24 Weeks of Pregnancy in Women With Inflammatory Bowel Disease,” by Meyer A, Neumann A, Drouin J, et al. Ann Intern Med [2022; 175(10) 1374-82].2022-12-1312 min

Evidence-Based GI: An ACG Publication and PodcastNSAID Use and the Risk of IBD Exacerbations: Fact or FictionPhilip Okafor, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “The Association Between Nonsteroidal Anti-Inflammatory Drug Use and Inflammatory Bowel Disease Exacerbations: A True Association or Residual Bias?” by Cohen-Mekelburg S, Van T, Wallace B, et al. Am J Gastroenterol [2022; 117 (11): 1851-57].2022-12-1315 min

Evidence-Based GI: An ACG Publication and PodcastRBX2660, a Donor Stool Product for Fecal Microbiota Transplant, Decreases Recurrent Clostridioides difficile Infection: The First FDA-Approved Live Biotherapeutic ProductCollen R. Kelly, MD and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACGdiscuss “Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile Infection,” by Khanna S, Assi M, Lee C. et al. Drugs [2022; 82: 1527-1538].2022-12-1319 min

Evidence-Based GI: An ACG Publication and PodcastVonoprazan, a Potassium-Channel Acid Blocker, is Superior to Lansoprazole for Managing Erosive EsophagitisEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “Vonoprazan versus Lansoprazole for Healing and Maintenance of Healing of Erosive Esophagitis: A Randomized Trial,” by Laine L, DeVault K, Katz P, et al. Gastroenterology [2022; In Press].2022-11-1113 min

Evidence-Based GI: An ACG Publication and PodcastReinvestigating the Lack of Association Between Proton Pump Inhibitor Use and Mortality by Accounting for Reverse CausationRavy Vajravelu, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Association of Proton Pump Inhibitor Use With All-Cause and Cause-Specific Mortality,” by Lo CH, Ni P, Yan Y, et al. Gastroenterology [2022; 163:852 – 61].2022-11-1124 min

Evidence-Based GI: An ACG Publication and PodcastICYMI: Surgery is Superior to Medical Therapy for PPI-Refractory Heartburn in the “Right” PatientsJennifer Kolb, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn,” by Spechler SJ, Hunter JG, Jones KM, et al. N Engl J Med [2019;381:1513-1523].2022-11-1117 min

Evidence-Based GI: An ACG Publication and PodcastAcute pancreatitis: Need IV fluid resuscitation but avoid a WATERFALL!Shria Kumar, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis,” by de-Madaria E, Buxbaum JL, Maisonneuve P, et al, published in N Engl J Med [2022;387(11):989-1000].2022-10-1809 min

Evidence-Based GI: An ACG Publication and PodcastHigh Adenoma Detection Rate Decreases Post-Colonoscopy CRC in FIT-Based Screening Program: Quality Matters!Joseph Sleiman, MD and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Adenoma Detection Rate and Risk for Interval Postcolonoscopy Colorectal Cancer in Fecal Immunochemical Test-Based Screening: A Population-Based Cohort Study,” by Wisse PHA, Erler N, de Boer SY, et al, published in Ann Intern Med [2022; In Press].2022-10-1818 min

Evidence-Based GI: An ACG Publication and PodcastColonoscopy Reduces CRC Incidence and CRC-Related Mortality…. If You Get It!Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death,” by Bretthauer M, Løberg M, Wieszczy P, et al, published in N Engl J Med [Oct 9, 2022].2022-10-1813 min

Evidence-Based GI: An ACG Publication and PodcastTime to Increase Adenoma Detection Rate Benchmarks for Screening ColonoscopiesEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease,” by Mahadevan U, Long MD, Kane SV, et al, published in Gastroenterology [2021 Mar;160(4):1131-1139].2022-09-2122 min

Evidence-Based GI: An ACG Publication and PodcastAchieve IBD Remission Before Pregnancy: PIANO Registry Data Shows Adverse Perinatal Outcomes For Infants Associated with IBD Flares and Steroid Use; and Continue Thiopurines and Anti-TNF Agents If Your IBD Patient Becomes PregnantEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “Exposure to Corticosteroids in Pregnancy Is Associated with Adverse Perinatal Outcomes Among Infants of Mothers with Inflammatory Bowel Disease,” by Odufalu FD, Long MD, Lin K, Mahadaven U for PIANO Investigators, published in GUT [2022; 71: 1766-72] and also “Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease,” by Mahadevan U, Long MD, Kane SV, et al, published in Gastroenterology [2021 Mar;160(4):1131-1139]2022-09-2116 min

Evidence-Based GI: An ACG Publication and PodcastICYMI-Pantoprazole Prophylaxis Does Not Reduce 90-day Mortality and Clinically Significant Adverse Events in ICU PatientsPhilip Okafor, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Pantoprazole in Patients at Risk for Gastrointestinal for Gastrointestinal Bleeding in the ICU,” by Krag M, Marker S, Perner A et al, published in NEJM [379; 23: 2018].2022-09-2115 min

Conversations on Healing PodcastHow Noise Affects Your Sleep and HealthMathias Basner, MD, PhD, MScEpi is a professor in the Department of Psychiatry at University of Pennsylvania in the School of Medicine. He is the Director of the Behavioral Regulation and Health Section of the Department of Psychiatry. His research in particular focuses on sleep loss and its effect on cognition, as well as how noise affects sleep. Dr. Basner is the Senior Associate editor of the Sleep Health journal, and he serves on the editorial board of the journal Frontiers in Physiology. He has published over 100 original research articles in addition to reviewing articles for scientific journals. 2022-08-3059 min

Evidence-Based GI: An ACG Publication and PodcastProphylactic Rifaximin Decreases Post-TIPS Hepatic EncephalopathyEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt : A Randomized Controlled Trial,” by Bureau et al, published in Ann Intern Med [2021 May;174(5):633-640].https://pubmed.ncbi.nlm.nih.gov/33524293/2022-08-1112 min

Evidence-Based GI: An ACG Publication and PodcastTiny Polyps-It’s OK to Remove Polyps equal or less than 3mm with Large Biopsy ForcepsShria Kumar, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy Among Small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial,” by Wei et al, published in Am J Gastroenterol [2022 Aug 1;117(8):1305-1310]. https://pubmed.ncbi.nlm.nih.gov/35467557/2022-08-1112 min

Evidence-Based GI: An ACG Publication and PodcastADR Isn’t the Only Game in Town: Proximal Serrated Lesion Detection Rates Predicts Interval Cancer RiskSwati Patel, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Serrated polyp detection and risk of interval post-colonoscopy colorectal cancer: a population-based study,” by van Toledo et al, published in Lancet Gastroenterol Hepatol [2022 Aug;7(8):747-754]. https://pubmed.ncbi.nlm.nih.gov/35550250/2022-08-1116 min

Evidence-Based GI: An ACG Publication and PodcastSER-109, an Oral Microbiome Therapy, Decreases Recurrent Clostridiodes difficile InfectionAssociate Editor Jessica Allegretti, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection” by Feuerstadt et al, published in N Engl J Med [2022;386(3):220-229]. https://pubmed.ncbi.nlm.nih.gov/35045228/2022-06-1611 min

Evidence-Based GI: An ACG Publication and PodcastWhen Is Routine Prophylactic Clipping Indicated Post-Polypectomy?Associate Editor Jeffrey Lee, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single-centre, randomised controlled trial” by Gupta et al, published in Lancet Gastroenterol Hepatol [2022;7(2):152-160]. https://pubmed.ncbi.nlm.nih.gov/34801133/2022-06-0913 min

Evidence-Based GI: An ACG Publication and PodcastTenapanor (IBSRELA) for Treatment of IBS-C: Effective over 26 WeeksEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “Efficacy of Tenapanor in Treating Patients With Irritable Bowel Syndrome with Constipation: A 26-Week, Placebo-Controlled Phase 3 Trial (T3MPO-2)” by Chey et al, published in Am J Gastroenterol [2021;116: 1294-1303]. https://pubmed.ncbi.nlm.nih.gov/33337659/2022-06-0211 min

Evidence-Based GI: An ACG Publication and PodcastLow Grade Dysplasia in Barrett’s Esophagus – Get Two Expert GI Pathologist Reviews and Repeat EGD After PPI TreatmentAssociate Editor Shria Kumar, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Discordance Among Pathologists in the United States and Europe in Diagnosis of Low-Grade Dysplasia for Patients With Barrett’s Esophagus” by Vennalaganti et al, published in Gastroenterology [2017 Feb;152(3):564-570.e4]. https://pubmed.ncbi.nlm.nih.gov/27818167/2022-05-0515 min

Evidence-Based GI: An ACG Publication and PodcastTherapeutic Drug Monitoring of Maintenance Infliximab Is Beneficial for Patients with Immunemediated Inflammatory DiseasesAssociate Editor Jessica R. Allegretti, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Effect of Therapeutic Drug Monitoring vs Standard Therapy During Maintenance Infliximab Therapy on Disease Control in Patients With Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial” by Syversen et al, published in JAMA [2021; 326(23):2375-2384]. https://pubmed.ncbi.nlm.nih.gov/34932077/2022-04-1411 min

Evidence-Based GI: An ACG Publication and PodcastEndoscopic Eradication Therapy for Neoplastic Barrett’s Esophagus Demonstrates 94% Treatment Success and Long-term DurabilityAssociate Editor Jennifer M Kolb MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Long-term Outcomes after Endoscopic Treatment for Barrett’s Neoplasia with Radiofrequency Ablation ± Endoscopic Resection: Results from the National Dutch Database in a 10-year Period” by Munster et al, published in Gut [2022;71:265-76]. https://pubmed.ncbi.nlm.nih.gov/33753417/2022-04-0717 min

Evidence-Based GI: An ACG Publication and PodcastIncreased Risk of Metachronous Neoplasia After Incomplete Polyp Resection – Time to CARE About Polypectomy Technique!Associate Editor Jeffrey Lee, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Recurrence of Colorectal Neoplastic Polyps After Incomplete Resection” by Pohl et al, published in Annals of Internal Medicine. [2021;174(10):1377-1384]. https://pubmed.ncbi.nlm.nih.gov/34370514/2022-02-2417 min

Evidence-Based GI: An ACG Publication and PodcastIt’s a Bad “Prep” Even Though the Patient Took It Correctly: Consider 15 mg Bisacodyl plus 4-Liter PEG Split Prep Before Next ColonoscopyEditor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discusses “A Multicenter Randomized Controlled Trial Comparing Bowel Cleansing Regimens for Colonoscopy After Failed Bowel Preparation” by Sey at al, published in Clinical Gastroenterology and Hepatology [2022;In Press]. https://pubmed.ncbi.nlm.nih.gov/34256147 2022-02-1713 min

Evidence-Based GI: An ACG Publication and PodcastEffectiveness of Intermittent Fasting for Weight Loss: It’s Not Just When You Eat, but What You Eat, Too!Associate Editor Sonali Paul, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men with Overweight and Obesity. The TREAT Randomized Clinical Trial” by Lowe et al, published in JAMA [2021; 181(6):883]. https://pubmed.ncbi.nlm.nih.gov/32986097/2022-02-1017 min

Evidence-Based GI: An ACG Publication and PodcastFamily Matters: Increased Risk of Colorectal Cancer among Individuals with Family History of PolypsAssociate Editor Ravy K. Vajravelu, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi FACG discuss “Risk of colorectal cancer in first degree relatives of patients with colorectal polyps: nationwide case-control study in Sweden” by Song et al, published in BMJ [2021;373:n877]. https://pubmed.ncbi.nlm.nih.gov/33947661/2022-02-0321 min

Evidence-Based GI: An ACG Publication and PodcastSlow Down to Speed Up Quality: Longer Withdrawal Time of 9 Versus 6 Minutes Increases Adenoma Detection RateAssociate Editor Jennifer M. Kolb MD, MSCS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss “Impact of 9-Minute Withdrawal Time on the Adenoma Detection Rate: A Multicenter Randomized Controlled Trial” by Zhao et al, published in Clinical Gastroenterology and Hepatology [2020;20:31553-6]. https://pubmed.ncbi.nlm.nih.gov/33220526/2022-01-2720 min

Evidence-Based GI: An ACG Publication and PodcastDrainage for Infected Pancreatic Necrosis – Earlier Is Not BetterAssociate Editor Shria Kumar, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss “Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis” by Boxhoorn et al, published in NEJM. [2021;15:1372-1381]. https://pubmed.ncbi.nlm.nih.gov/34614330/2022-01-2016 min

Evidence-Based GI: An ACG Publication and PodcastHereditary Syndrome Risk Assessment in all Colorectal Cancer Patients: Keep it Simple!Associate Editor Swati Patel, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss “Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative” by Pearlman et al, published in JCO Precision Oncology [2021;5:779-91]. https://pubmed.ncbi.nlm.nih.gov/34250417/2022-01-1314 min

Evidence-Based GI: An ACG Publication and PodcastTreating All the Symptoms of IBS-C: Linaclotide Significantly Decreases Abdominal Pain, Bloating, and DiscomfortAssociate Editor Jill Deutsch, MD and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss “Efficacy of Linaclotide in Reducing Abdominal Symptoms of Bloating, Discomfort, and Pain: A Phase 3B Trial Using a Novel Abdominal Scoring System” by Chang et al, published in American Journal of Gastroenterology [2021;116: 1929-37]. https://pubmed.ncbi.nlm.nih.gov/34465695/2022-01-0617 min

Evidence-Based GI: An ACG Publication and PodcastPiecemeal Cold Snare Polypectomy of Large SSP: Cold Is the New HotAssociate Editor Swati Patel, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss Piecemeal cold snare polypectomy versus conventional endoscopic mucosal resection for large sessile serrated lesions: a retrospective comparison across two successive periods bt Van Hattem WA, published in Gut [2021;70:1691-97]. https://doi.org/10.1136/gutjnl-2020-321753 2021-10-2814 min

Evidence-Based GI: An ACG Publication and PodcastOnce-Weekly Semaglutide in Adults with Overweight or ObesityAssociate Editor Sonali Paul, MD, MS and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss Semaglutide Treatment Effect in People with Obesity (STEP) Investigators. Once-Weekly Semaglutide in Adults with Overweight or Obesity by Wilding et al, published in the New England Journal of Medicine [2021; 384: 989-1002. https://www.nejm.org/doi/10.1056/NEJMoa2032183 2021-10-2115 min

Evidence-Based GI: An ACG Publication and PodcastScreening Colonoscopy Decreases Colorectal Cancer Incidence and Related Mortality in Healthy Patients Over 75Associate Editor Jeffrey Lee, MD, MPH and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss Association of Screening Lower Endoscopy with Colorectal Cancer Incidence and Mortality in Adults Older than 75 Years by Ma et al, published in .JAMA Oncology [2021;7(7):985-992]. https://doi.org/10.1001/jamaoncol.2021.1364 2021-10-1415 min

Evidence-Based GI: An ACG Publication and PodcastAcute Myeloid Leukemia and Myelodysplastic Syndrome with IBD and Thiopurines Impact on RiskAssociate Editor Ravy K. Vajravelu, MD, MSCE and Editor-in-Chief Philip Schoenfeld, MD, MSEd, MScEpi, FACG discuss Incidence of Acute Myeloid Leukemia and Myelodysplastic Syndrome in Patients with Inflammatory Bowel Disease and the Impact of Thiopurines on Their Risk by Kahn et al., published in The American Journal of Gastroenterology [2021; 116: 741-47]. www.doi.org/10.14309/ajg.0000000000001058 2021-10-0713 min