Shows
聊聊Sci200-脑肿瘤的神经科学这篇文章概述了神经元活动如何强有力地驱动包括成人和儿童高级别胶质瘤在内的脑癌的发生、生长、侵袭和治疗抵抗。这些机制包括神经元活动调控的旁分泌信号和神经元-胶质瘤突触的直接电化学通讯。此外，文章还探讨了脑癌如何反过来重塑神经回路，增加兴奋性，从而加剧肿瘤的促进效应，并讨论了这些原则对其他原发性和转移性脑癌的影响，强调了从神经科学角度研究癌症的重要性。References: Monje, Michelle. "The neuroscience of brain cancers." Neuron 113.17 (2025): 2734-2739.
2025-11-0123 min
Paper Talk200-The Neuroscience of Brain CancersThis article explores the emerging field of cancer neuroscience, specifically focusing on the reciprocal interactions between the nervous system and brain cancers like gliomas and metastases. The central theme is that neuronal activity robustly drives the initiation, growth, invasion, and treatment resistance of brain cancers, often by hijacking normal mechanisms of neural development and plasticity. This occurs through several mechanisms, including neuronal-activity-regulated paracrine signaling involving factors like neuroligin-3 and direct electrochemical communication via neuron-to-glioma synapses (e.g., glutamatergic, GABAergic, and cholinergic). Furthermore, the source details how gliomas, in turn, remodel neural circuits to increase excitability and connectivity, contributing to...
2025-11-0121 min
The Future of EverythingThe future of cancer neuroscienceNeurologist Michelle Monje studies the close relationship between cancer and the nervous system, particularly in an aggressive brain cancer that often strikes in childhood. Her research shows that the cancer cells are electrically integrated into the brain itself and these connections actually help the cancer to grow. Monje and collaborators have now developed an immunotherapy that has shown great promise in mice and early human trials. One patient had a “complete response” and is cancer-free four years after treatment, Monje tells host Russ Altman on this episode of Stanford Engineering’s The Future of Everything podcast.Have a ques...
2025-08-1531 min
Neural Implant podcast - the people behind Brain-Machine Interface revolutionsBen Woodington on Coherence Bio's Revolutionary Cancer Reprogramming ApproachIn this episode of the Neural Implant Podcast, we sit down with Ben Woodington, co-founder of Coherence Bio, a groundbreaking medical technology company pioneering a new frontier in cancer treatment. By integrating neurotechnology, neurobiology, and machine learning, Coherence is building a platform that doesn't just fight cancer—it manages it in real time. Ben shares how Coherence is moving beyond the traditional "cut, burn, poison" model of oncology, and instead focusing on precision neuromodulation to monitor and control cancer progression—offering hope for 24/7 adaptive treatment with fewer side effects and better quality of life. Their platform, SOMA, is t...
2025-08-1123 min
聊聊Sci020-神经-免疫系统在胶质瘤免疫疗法中的复杂相互作用这篇文章概述了神经-免疫系统在胶质瘤免疫疗法中的复杂相互作用。它解释了中枢神经系统（CNS）不再被认为是免疫特权区，而是拥有独特的免疫微环境，对大脑健康和CNS肿瘤的免疫疗法具有重要影响。文章探讨了不同免疫细胞在CNS及其边界的独特作用，以及它们如何与神经元和星形胶质细胞进行双向交流。文献还回顾了针对高级别胶质瘤（HGGs）的多种免疫疗法策略，包括免疫检查点抑制剂、嵌合抗原受体T细胞（CAR T细胞）疗法、溶瘤病毒和疫苗疗法，并讨论了它们各自的挑战和未来方向。最后，它详细阐述了免疫疗法可能引起的神经毒性，例如细胞因子释放综合征（CRS）和免疫效应细胞相关神经毒性综合征（ICANS），并强调了优化治疗以实现持久疗效的重要性。References: Song, Kun-Wei, Michael Lim, and Michelle Monje. "Complex neural-immune interactions shape glioma immunotherapy." Immunity 58.5 (2025): 1140-1160.
2025-07-1731 min
DynamisradioLa tumba vacía (Juan 20) - Ruta 66 con José de SegoviaLa fe cristiana depende de la Historia de una manera distinta a cualquier otra religión. Si el origen del Islam o el budismo no es como ellos cuentan, eso no cambia nada su enseñanza y la verdad del camino al que su fe apunta, pero si Jesús no resucitó, dice Pablo que nuestra fe no tiene sentido (1 Corintios 15:14).
John Michael Talbot nació en una familia metodista de Oklahoma, pero como tantos hippies empezó a tocar la guitarra con su hermano Terry en un grupo de "country-rock", mientras buscaba el sentido de su vida en la religión nativa...
2025-07-0250 min
Podcast El pulso de la VidaLa tumba vacía (Juan 20) - Ruta 66 con José de SegoviaLa fe cristiana depende de la Historia de una manera distinta a cualquier otra religión. Si el origen del Islam o el budismo no es como ellos cuentan, eso no cambia nada su enseñanza y la verdad del camino al que su fe apunta, pero si Jesús no resucitó, dice Pablo que nuestra fe no tiene sentido (1 Corintios 15:14).
John Michael Talbot nació en una familia metodista de Oklahoma, pero como tantos hippies empezó a tocar la guitarra con su hermano Terry en un grupo de "country-rock", mientras buscaba el sentido de su vida en la religión nativa...
2025-07-0250 min
All Things PhotonicsSpotlight: Frank Winkler, Professor for Neuro-Oncology, Heidelberg UniversityDr. Frank Winkler, at Heidelberg University focuses on the emerging field of cancer neuroscience, and the way brain cancers proceed. Winkler has used two-photon imaging to confirm that glioma cells link through microtubes, similar to typical neurons in the brain. His groundbreaking work has earned him the 2025 Brain Prize by the Lundbeck Foundation, alongside Dr. Michelle Monje. And in this spotlight conversation, Winkler discusses the journey he and Dr. Monje took to arrive at their conclusions, and how the shape of cancer research, particularly under the umbrella of neuroscience, is changing.
Spotlight from "All Things...
2025-04-1438 min
Conversations @ The Salt LineA Conversation with Michelle MonjeIn this episode of Conversations @ the Salt Line host Wesley Dixon chats with Dr. Michelle Monje '98 who is a 2021 recipient of the MacArthur "Genius" award and the Milan Gambhir Professor of Pediatric Neuro-Oncology at Stanford University School of Medicine. Wesley and Dr. Monje discuss the intersections of clinical care and research as it relates to pediatric oncology and explore the complex ethical questions associated with Dr. Monje's groundbreaking research.
2025-03-101h 02
The Premed YearsUncertainty to Conviction: A Stanford MD/PhD’s Journey(00:01) Journey to Medicine(10:30) Navigating Medicine and Research Paths(27:22) Navigating Doubt and Motivation in Medicine(36:54) Embracing Doubt in Finding DirectionNavigating the uncertainty of a career in medicine is no small feat, as Kamsi shares in our latest episode. From her time at Stanford Med to translational research at the NIH, Kamsi's journey is a testament to the power of experiences in shaping career decisions. As she reflects on the challenges of medical school and the invaluable influence of her physician mother, listeners gain insight into the emotional demands and rigorous application...
2025-03-0538 min
From Our Neurons to YoursHow the brain helps cancers grow | Michelle MonjeToday, we're talking with Stanford neuro-oncologist, Michelle Monje. This is actually the third time we've had Michelle on the show, in part because she's been a pioneer of three exciting frontiers in neuroscience — so far! This week, we're going to talk about cancer neuroscience. Michelle founded this new field with her discovery that deadly brain tumors not only link up physically with the healthy brain tissue surrounding them, but the cancers actually need the brain's electrical activity to grow and spread.It turns out that many cancers — not only in the brain — depend on nervous system...
2024-08-1521 minFrom Our Neurons to YoursHow a new kind of brain plasticity could help make sense of addiction | Michelle Monje and Rob MalenkaThis week, we're diving into recent research that sheds light on a new form of brain plasticity involving changes in the insulation of nerve fibers — called myelin. It turns out that myelin plasticity is implicated in a number of serious conditions, from epilepsy to drug abuse and addiction.We're excited to bring back two previous guests on the show to share their insights on this previously unknown form of plasticity: Stanford psychiatry professor Rob Malenka (S1 E1 - Psychedelics and Empathy), a pioneer in the study of synaptic plasticity and addiction, and neuro-oncologist Michelle Monje (S1 E1...
2024-06-2022 min
Ground TruthsMichelle Monje: The Brain in Long Covid and CancerTranscript with audio and relevant external links, recorded on 6 Feb 2024Eric Topol (00:05):Hello, this is Eric Topol with Ground Truths, and I have a remarkable guest with me today, Professor Michelle Monje, who is from Stanford, a physician-scientist there and is really a leader in neuro-oncology, the big field of cancer neuroscience, neuroinflammation, and she has just been rocking it recently with major papers on these fields, no less her work that's been on a particular cancer, brain cancer in kids that we'll talk about. I just want to give you...
2024-02-2543 min
Brain & LifeBMX Athlete Josh Perry's Perseverance Living with Brain Tumors In this special episode, Dr. Reena Thomas, neuro-oncologist and clinical associate professor at Stanford Medicine, joins as a guest co-host to talk with former professional BMX athlete now personal coach Josh Perry. Josh shares his experience of being diagnosed with brain tumors known as meningiomas, the surgeries that he has undergone to treat them, and how he moves forward by talking about his experience with others. Next, Dr. Thomas speaks with Dr. Michelle Monje, pediatric neuro-oncologist and professor of neurology, of neurosurgery, of pediatrics, of
2023-07-2739 min
Triatleta Real3. Michelle Echeverría. La vida detrás de los kilómetros de una campeona de ultradistancia.Michelle Echeverría, la roja, cómo le dicen sus amigos cercanos, ha vivido experiencias y aventuras que muchos ni siquiera imaginan y pocos se animan a intentarlo.
La ultradistancia fué su primer acercamiento con el deporte de resistencia y desde el primer minuto supo que las largas y solitarias horas de ésta modalidad serían su terapia y su pasión.
Te invito a conocer la mentalidad guerrera y la templanza digna de un monje con la que Mich enfrenta cada competencia y su vida diaria.
#TRIATL...
2023-07-251h 45
Childhood Cancer Talk Radio PodcastsAn Inside Look (Part II) at DIPG, Childhood Brain Cancer with Wendy Fachon and Janet DemeterBoth advocates and moms share the parallel of their personal experiences with their sons who were both diagnosed with DIPG, with Wendy's son Neil Fachon diagnosed at age 19 in 2016, and Janet's son Jack Demeter diagnosed in 2012. A continuation of a deep conversation from last week, the two share their hope and inspiration for continued advocacy as well as some of their hard-fought successes in the field. Despite the growing attention to the pediatric brain cancer research space, nothing has to date changed for the average family with a child diagnosed with DIPG from the experience 60 years ago. The two friends...
2023-05-2600 minFrom Our Neurons to YoursBrain Fog | Michelle MonjeOne of the strangest and most disconcerting things about the COVID 19 pandemic has been the story of long COVID.Many COVID long-haulers have continued experiencing cognitive symptoms long after their initial COVID infection — loss of attention, concentration, memory, and mental sharpness — what scientists are calling "brain fog". For some patients, the condition is so serious that it can be impossible to go back to their pre-COVID lives.Today’s guest, actually had an early intuition that COVID-19 could trigger a neurological health crisis.Michelle Monje is a pediatric neuro-oncologist here at Stanford...
2023-05-1120 min
Skimm ThisTaking Care of Business: Four-Day Work Week, Facebook vs. TikTok, Fake LinkedIn Profiles
First: We’ve got the context on the biggest stories from the week – from the war in Ukraine, to the latest booster shot recommendations. And a major immigration announcement from the White House.
Next up: A bombshell new report revealed that Facebook’s parent company hired a private firm to dish dirt on fellow social media giant TikTok. We’ll skimm the digital drama…in 60 seconds.
ICYMI: As we head into the third year of the pandemic, scientists are taking a closer look at long COVID symptoms. And new research suggests there are a lot of similarities between long COVID brain fog...
2022-03-3129 minChildhood Cancer Talk Radio PodcastsFrom Creating Hope to Kids First, Cancer Moonshot to the Fairness to Kids With Cancer Act; A Look Backward and Forward for Childhood Cancer AdvocacyA look back and forward for the childhood cancer awareness movement, we begin with the Creating Hope Act of 2012, the Alexis Agin Identity Theft Protection Act of 2013, the Gabriella Miller Kids First Research Act of 2014, the DIPG Awareness Resolution, forward to the Give Kids A Chance Act. Mina Carroll gives her famous, drop-mike "Bean's Ball" speech which inspired today's H. R. 2210, the Fairness to Kids With Cancer Act. Featured also is the signing, by President Obama, of the Gabriella Miller Kids First bill, and the urgency powerfully symbolized by H. Res. 404, the DIPG Awareness Resolution, or #Moonshot4Kids. Included is...
2022-01-1400 min
A fume de carozo11x17 Programa homenaxe a Rosalía de CastroEste foi o programa número 289 de "A fume de carozo", que se emitiu o 18 de febreiro de 2020. Está promovido polo Equipo de Dinamización da Lingua Galega do Colexio Calasanz (PP. Escolapios) da Coruña.
O programa homenaxeaba a Rosalía de Castro co gallo do seu nacemento e foi presentado polas seguintes alumnas de 4ºA ESO: Noelia Gutiérrez Zuluaga, Andrea López López, Mecía Riveiro Pérez, Alba Tahoces Rodríguez e Noa Varela...
2020-02-1801 minA fume de carozo11x17 Programa homenaxe a Rosalía de CastroEste foi o programa número 289 de "A fume de carozo", que se emitiu o 18 de febreiro de 2020. Está promovido polo Equipo de Dinamización da Lingua Galega do Colexio Calasanz (PP. Escolapios) da Coruña.
O programa homenaxeaba a Rosalía de Castro co gallo do seu nacemento e foi presentado polas seguintes alumnas de 4ºA ESO: Noelia Gutiérrez Zuluaga, Andrea López López, Mecía Riveiro Pérez, Alba Tahoces Rodríguez e Noa Varela Fernández. Recitaron en directo poemas de Rosalía os seguintes alumnos e alumnas de Primaria: Laura Blanco e Icía Vara (1ºEP...
2020-02-1800 min
FrancoinformadorLa beba Matilde recibe el tratamiento más caro del mundo.EL TRATAMIENTO MÁS CARO DEL MUNDO. Matilde, la bebé de tres meses que padece atrofia muscular espinal tipo 1 y que ha logrado movilizar a la sociedad portuguesa para financiar los casi dos millones de euros que cuesta el medicamento que la puede curar, comienza hoy su tratamiento en el Hospital Santa Maria de Lisboa. Durante las últimas cuatro semanas, Matilde estuvo en observación sin ningún tipo de infección bacteriana y hoy estará 6 horas sin respiración artificial para ser tratada con el medicamento. Se trata del fármaco 'Zolgensma', un medica...
2019-08-2800 min
The Future of EverythingMichelle Monje: New therapies for brain cancerBrain cancers are known to be elusive and clever killers, but Michelle Monje, associate professor of neurology and neurological sciences, is helping to find new treatments through a better understanding of how healthy brain cells develop and how cancers often hijack those very same processes in order to grow themselves.
Monje says that the last decade has seen tremendous progress in our understanding of how cancers thrive and in the development of new drugs and therapies to kill the killers. Unfortunately, many chemotherapy drugs powerful enough to kill cancers also cause lasting impairment of the patient’s co...
2019-04-2227 minChildhood Cancer Talk Radio PodcastsH.Res.69: Crucial Awareness Supports Greater Research from the Tragic Example of DIPGDr. Michelle Monje Deissiroth of Stanford University and Dr. Adam Green of University of Colorado, Denver, join us to discuss the breadth of their research as pediatric neuro-oncologists, specifically regarding DIPG, diffuse intrinsic pontine glioma. They discuss how they were inspired to study this particular disease as a focal point for much of their research, and the general state of the research landscape with regard to the challenges facing treatment and the hope of new discoveries which give important clues to causes and biological understanding.
Dr. Monje and Dr. Green were conferring experts of Congressman Steve Knight's (CA-25) H.Res.69...
2017-12-0700 min
Sucio TatamiSucio Tatami 1x5 Especial 10º Aniversario. 'Las 36 Cámaras de Shaolin' (1978), Jorge Endrino Asiateca 'Kung Fu Girls'Bienvenidos a esta nueva edición del podcast: “Sucio Tatami”, un rincón dedicado exclusivamente al cine de acción, artes marciales y todo lo relacionado con la fiebre amarilla del Kung Fu.
Un 4 de abril de 2007, hace justo 10 años, nuestro pequeño blog: “Saca Tus Sucias Pezuñas de mi Tatami” realizaba su primera entrada en la red.
Mucho tiempo ha pasada desde aquel día, sin embargo, es un enorme orgullo poder estar hoy junto a vosotros para celebrar tan señalada fecha en un programa especial. En primer lugar, como es de bien nacido ser agradecido, hacemos un peque...
2017-04-042h 23
NeuwriteWestBrains & Bourbon Ep18 Rethinking Brain TumorsIn this episode of Brains & Bourbon, Viola Caretti explains how a small group of scientists and a dedicated community of affected families have come together in their search for a cure for a deadly form of childhood brain cancer.
Viola is a postdoctoral research fellow in Michelle Monje's lab here at Stanford.
2014-09-1959 min