Shows
Trials and Tribulations | Oncology Trials PodcastEpisode 15: Stereotactic Radiotherapy in Renal Cell Cancers with Professor Shankar SivaTune in to this must listen episode with Professor Shankar Siva from the Peter MacCallum Cancer Centre. We revisit the role of radiotherapy in renal cell cancers, focusing on stereotactic radiotherapy. We discuss the set up of a phase III clinical trial , the importance of collaboration and patient involvement as well as clinically relevant endpoints, patient reported-outcomes and health economics. 2025-05-1633 minTrials and Tribulations | Oncology Trials PodcastEpisode 14: Oncolytic Viruses & Clinical Trials: Expert Insights with Professor Kevin HarringtonTune in to this must listen episode with Professor Kevin Harrington, Head of Radiotherapy and Imaging at the Institute of Cancer Research and Consultant Clinical Oncologist at The Royal Marsden Hospital. We explore the challenges of conducting clinical trials in cancer research, with a special focus on oncolytic viruses. Professor Harrington delves into the intricacies of trial design, the balance between safety and efficacy, and the patient-centric approach shaping the future of oncology. He also discusses regulatory and funding obstacles and offers valuable insights for early-career researchers navigating this complex landscape. 2025-03-1737 minTrials and Tribulations | Oncology Trials PodcastEpisode 13: Breast Cancer Radiotherapy Trials featuring Dr Anna KirbyTune in to this must-listen episode with Dr. Anna Kirby, Consultant Clinical Oncologist at the Royal Marsden Hospital and Institute of Cancer Research, London, UK.
She shares insights into the challenges and successes of designing and conducting breast cancer radiotherapy trials, including FAST-FORWARD Boost, and highlights the crucial role of patient and public involvement.
As a past president of ESTRO, Dr. Kirby also reflects on the impact of international guidelines, discussing both their successful implementation and the challenges faced in ensuring widespread adoption.
2025-02-0332 minTrials and Tribulations | Oncology Trials PodcastEpisode 12: Involve Your Urologist! Challenges facing surgical trials featuring Professor Declan MurphyJoin us for an engaging episode with Professor Declan Murphy, Co-host of the GU Cast Podcast, Director of GU Oncology and Robotic Surgery at the Peter MacCallum Cancer Centre, Melbourne, Australia. We explore the challenges of surgeon heterogeneity, the critical role of equipoise, and why involving urologists early is essential for the success of clinical trials. Discover how multidisciplinary collaboration, cutting-edge innovation, and advanced imaging are transforming the landscape of urological surgical trials!2025-01-0733 minTrials and Tribulations | Oncology Trials PodcastEpisode 11: Women in Surgery, Navigating the Intersection of Academia and Clinical Practice with Dr Renu EapenJoin us for this must-listen episode with Dr. Renu Eapen, co-host of GU Cast podcast! She shares insights on balancing clinical practice and research and navigating PhD challenges. We discuss the importance of good mentorship and women’s representation in the field. We also hear about her exciting work on the Lutectomy trial.
2024-12-1025 minTrials and Tribulations | Oncology Trials PodcastEpisode 10: Utilising NHS data for trial follow-up and the role of imaging in outcome assessment featuring Mr Ashwin SachdevaIn this episode, Mr Ashwin Sachdeva, Consultant Urologist and Academic Clinical Lecturer at the University of Manchester discusses the following:
00:00 Introduction
02:10 Utilising NHS Data for long-term follow-up
04:40 Fracture rates and hormone therapy in prostate cancer
07:05 Challenges in trial follow-up and data collection
11:18 Imaging and its role in prostate cancer
17:58 Prospective imaging collection in the STAMPEDE trial
22:32 Balancing surgery and research
26:31 Future directions in prostate cancer research2024-10-2528 minTrials and Tribulations | Oncology Trials PodcastEpisode 9: PSMA Theranostics and Imaging Trials featuring Professor Michael HofmanIn this episode, Professor Michael Hofman shares his experience with PSMA theranostics trials in prostate cancer, particularly focusing on the ProPSMA and TheraP trials.
He emphasises the advancements in PSMA PET imaging, highlighting its prognostic and predictive significance, as well as the importance of accurate imaging in guiding treatment decisions.
He also addresses the challenges of conducting imaging clinical trials and discusses the importance of industry collaboration in research.2024-10-0835 minTrials and Tribulations | Oncology Trials PodcastEpisode 8: Early Phase Clinical Trials featuring Professor Udai BanerjiIn Episode 8, featuring Professor Udai Banerji, we discuss the set up of early phase clinical trials.2024-07-3128 minTrials and Tribulations | Oncology Trials PodcastEpisode 7: International Clinical Trial Collaborations featuring Professor Neha VapiwalaIn Episode 7, featuring Professor Neha Vapiwala, we discuss the strengths and challenges of clinical trial setup in the US, the intricacies of international collaborations, and provide an overview of next-generation imaging with PSMA PET in the STAMPEDE2 and INDICATE clinical trials.
2024-07-1636 minTrials and Tribulations | Oncology Trials PodcastEpisode 6: International Clinical Trial Collaborations featuring Professor Piet OstIn episode 6, featuring Professor Piet Ost, we explore what works well and the challenges with international clinical trial collaborations.2024-06-0717 minTrials and Tribulations | Oncology Trials PodcastEpisode 5: International Clinical Trial Collaborations featuring Professor Silke Gillessen and Professor Vedang MurthyIn episode 5, featuring Professor Silke Gillessen and Professor Vedang Murthy, we explore what works well and the challenges with international clinical trial collaborations.
Timestamps:
(00:00)- Introduction
(00:28) - Silke Gillessen
(05:02) - Interlude
(05:05) - Vedang Murphy2024-05-1610 minTrials and Tribulations | Oncology Trials PodcastEpisode 4: STAMPEDE trial Metformin Comparison, Access to routine data and Clinical Trial Regulation with Professor Silke GillessenIn Episode 4, featuring Professor Silke Gillessen, we explore the STAMPEDE trial’s Metformin comparison, discussing its rationale and predicted outcomes. We also tap into challenges with access to routine data and clinical trial regulation.2024-05-1014 minTrials and Tribulations | Oncology Trials PodcastEpisode 3: STAMPEDE2 trial database and first site initiation visitIn episode 3, we discuss the set-up of the STAMPEDE2 trial database and the first site initiation visit (SIV). We also give an overview of the STAMPEDE2 trial design.2024-05-0312 minTrials and Tribulations | Oncology Trials PodcastEpisode 2: Access to routine data in clinical trialsIn episode 2, we discuss the challenges that clinical trials face in accessing routinely collected data.2024-04-3018 minTrials and Tribulations | Oncology Trials PodcastEpisode 1: STAMPEDE2 trial site set-up and ethical issuesIn episode 1, we discuss the STAMPEDE2 trial site set-up, ethics and MHRA issues.2024-04-2210 min