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Showing episodes and shows of
Sonya Del Tredici And John Keenan
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Addiction Medicine Journal Club
63. Buprenorphine Dose and Neonatal Opioid Withdrawal
In episode 63 we discuss the association between buprenorphine dose and neonatal opioid withdrawal syndrome. Marc B, Marion D, François B, Lakshmipriya L. Is buprenorphine maternal dose associated with neonatal opioid withdrawal syndrome severity? Am J Addict. 2025 Jan;34(1):15-20. We also discuss private equity in health care and nitrous oxide (Galaxy Gas). AMA Journal of Ethics: Is Pursuing Profit Commensurable With Providing Good Health Care? David T. Zhu: presentation on private equity at the 2025 From Research to Recovery Conference.
2025-07-28
36 min
Addiction Medicine Journal Club
62. Naltrexone Pills vs Injections for Alcohol Use Disorder
In episode 62 we discuss the article “Oral vs Extended-Release Injectable Naltrexone for Hospitalized Patients with Alcohol Use Disorder.” Magane KM, et al.Oral vs Extended-Release Injectable Naltrexone for Hospitalized Patients With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Intern Med. 2025 Jun 1;185(6):635-645. We also discuss reduced overdose deaths and changes in buprenorphine labelling to include higher doses. NPR:Drug deaths plummet among young Americans as fentanyl carnage eases Federal Register:Modifications to Labeling of Buprenorphine-Containing Transmucosal Products for the ...
2025-07-14
36 min
Addiction Medicine Journal Club
61. Safety of BuprenorphineNaloxone vs. Buprenorphine in Pregnancy
In episode 61 we discuss pregnancy outcomes with bup/nlx compared to bup alone. Straub L, et al. Comparative Safety of In Utero Exposure to Buprenorphine Combined With Naloxone vs Buprenorphine Alone. JAMA. 2024 Sep 10;332(10):805-816. doi: 10.1001/jama.2024.11501. We also discuss the elimination of SAMHSA and methamphetamine-related deaths. STAT News: Trump’s mental health and addiction problem New York Times: As Fentanyl Deaths Slow, Meth Comes for Maine --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To...
2025-06-16
34 min
Addiction Medicine Journal Club
60. Lisdexamfetamine for methamphetamine use disorder
In episode 60 we discuss treating methamphetamine use disorder with lisdexamfetamine (Vyvanse). Ezard N, et al; The LiMA Investigator Group. Lisdexamfetamine in the treatment of methamphetamine dependence: A randomised, placebo-controlled trial. Addiction. 2024 Dec 19. We also discuss why some people don’t get hangovers, and tianeptine, otherwise known as gas station heroin. New York Times:The People Who Never Get Hangovers Pain Therapeutics:Tianeptine, an Antidepressant with Opioid Agonist Effects: Pharmacology and Abuse Potential, a Narrative Review --- This podcast offers ca...
2025-05-26
42 min
Addiction Medicine Journal Club
59. Low-Dose Buprenorphine Initiation (Micro-induction)
In episode 59 we discuss outpatient low-dose initiation of buprenorphine. Suen LW, et al. Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl. JAMA Netw Open. 2025 Jan 2;8(1):e2456253. We also discuss impulse control dysregulation from ropinerole, and the new non-opioid painkiller, suzetrigine. BBC:Prescription medication made me a gambling addict Grall-Bronnec M, et al.Dopamine agonists and impulse control disorders: a complex association. DrugSaf. 2018;41(1):19-75. FDA:FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pa...
2025-05-05
34 min
Addiction Medicine Journal Club
58. Semaglutide for Alcohol Use Disorder (RCT)
In episode 58 we discuss a randomized controlled trial of semaglutide for alcohol use disorder. Hendershot CS, Bremmer MP, Paladino MB, Kostantinis G, Gilmore TA, Sullivan NR, Tow AC, Dermody SS, Prince MA, Jordan R, McKee SA, Fletcher PJ, Claus ED, Klein KR. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2025 Feb 12:e244789. We also discuss benzodiazepine tapering guidelines and new ways to use Sublocade. ASAM Clinical Practice Guideline on Benzodiazepine Tapering Sublocade label changes --- This podc...
2025-04-14
40 min
Addiction Medicine Journal Club
Articles That Changed Our Practice 2025 (Part 2)
In this episode we discuss 4 more articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now. Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial. JAMA. 2024 May 28; 331(20):1722-1731. Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2417377. Understanding the shared meaning of recovery from substance use disorders: New findings from the What is Recovery? Study. Substance Abuse: Research and T...
2025-03-24
32 min
Addiction Medicine Journal Club
Articles That Changed Our Practice 2025 (Part 1)
In this episode we discuss 4 articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now.Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures. Journal of Substance Use and Addiction Treatment, Volume 158, 2024. 209252, ISSN 2949-8759.Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024 Mar 4;7(3):e243387.Association of Cannabis Use With Cardiovascular Outcomes Among US Adults. J Am Heart Assoc. 2024 Mar 5;13(5):e030178.Association of random and observed urine drug...
2025-03-16
36 min
Addiction Medicine Journal Club
57. What is Recovery?
In episode 57 we discuss a new definition of recovery.Zemore SE, Ziemer KL, Gilbert PA, Karno MP, Kaskutas LA. Understanding the Shared Meaning of Recovery From Substance Use Disorders: New Findings From the What is Recovery? Study. Subst Abuse. 2023 Sep 15;17:11782218231199372.We also discuss sports betting and why more people aren’t prescribing buprenorphine.STAT News: The misguided reason why providers aren’t prescribing more buprenorphine for opioid use disorderScientific American: How ‘Dark Patterns’ in Sports Betting Apps Keep Users Gambling---This podcast offers category 1 and MATE-ACT...
2025-02-24
41 min
Addiction Medicine Journal Club
56. How Many Quit Attempts Does It Take
In episode 56 we discuss how many attempts it takes to quit using addictive substances.Fontes RM, Tegge AN, Freitas-Lemos R, Cabral D, Bickel WK. Beyond the first try: How many quit attempts are necessary to achieve substance use cessation? Drug Alcohol Depend. 2024 Dec 8;267:112525. doi: 10.1016/j.drugalcdep.2024.112525. Epub ahead of print. PMID: 39719807.We also discuss capping nicotine content in cigarettes and how exercise affects cravings.Reuters: US regulators propose capping nicotine in cigarettes at non-addictive levelsAddictive Behaviors: Ding F, Jia S, Wang P, Liu C, Li Y. Effect...
2025-02-10
39 min
Addiction Medicine Journal Club
55. How Buprenorphine Works in Pregnancy
In episode 55 we discuss the pharmacokinetics and pharmacodynamics of buprenorphine in pregnancy. Caritis, Steve N. MD; Venkataramanan, Raman PhD. A Pharmacologic Evaluation of Buprenorphine in Pregnancy and the Postpartum Period. Journal of Addiction Medicine ():10.1097/ADM.0000000000001380, September 2, 2024. We also discuss fraud in Baltimore recovery houses, and the doubling of alcohol-related deaths. The New York Times: They Entered Treatment. Drugs, Overdoses and Deaths Followed. The New York Times: Alcohol Deaths Have More Than Doubled in Two Decades, Study Finds --- This podcast offers category...
2025-01-27
35 min
Addiction Medicine Journal Club
54. High Daily Doses of Buprenorphine
In episode 54 we discuss an article about 24-mg daily of buprenorphine and behavioral health hospitalizations. Axeen S, Pacula RL, Merlin JS, Gordon AJ, Stein BD. Association of Daily Doses of Buprenorphine With Urgent Health Care Utilization. JAMA Netw Open. 2024 Sep 3;7(9):e2435478. We also discuss the decline in overdose deaths and RFK’s experience with recovery. The White House: Biden-Harris Administration Marks Historic Progress Reducing Overdoses Across the Country The New York Times: ROBERT KENNEDY JR. ADMITS HE IS GUILTY IN POSSESSING HEROIN Robert F. Ke...
2025-01-14
42 min
Addiction Medicine Journal Club
53. Methadone Vs. Buprenorphine
In episode 53 we discuss an article comparing treatment retention and mortality in patients who are prescribed methadone vs. buprenorphine/naloxone for treatment of opioid use disorder. Nosyk B, Et al. Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder. JAMA. 2024 Oct 17. We also discuss the Modernizing Opioid Treatment Access Act, engaging non-abstinent patients in treatment, and hostility to medications with the recovery community. Modernizing Opioid Treatment Access Act (MOTAA) (H.R.1359 / S. 644) ASAM: Engagement and Retention of Nonabstinent Patients in Substance Use Treatment STA...
2024-12-30
39 min
Addiction Medicine Journal Club
52. Buprenorphine-precipitated Fentanyl Withdrawal
In episode 52 we discuss precipitated withdrawal in the era of fentanyl. Thakrar AP, Et al. Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl. JAMA Netw Open. 2024 Sep 3;7(9):e2435895. We also discuss kratom, brain injury after overdose, and syringe services. The Kratom Sobriety Podcast Making Kratom Safer The Conversation: Brain injury after overdose is a hidden epidemic NIDA: Syringe services for people who inject drugs are enormously effective, but remain underused --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES an...
2024-12-16
33 min
Addiction Medicine Journal Club
51. Fun Activities and Recovery
In episode 51 we discuss the connection between fun activities and success in recovery from substance use disorder. Acuff, S. F., Ellis, J. D., Rabinowitz, J. A., Hochheimer, M., Hobelmann, J. G., Huhn, A. S., & Strickland, J. C. (2024). A brief measure of non-drug reinforcement: Association with treatment outcomes during initial substance use recovery. Drug and Alcohol Dependence, 256, 111092. We also discuss whether people know their PCP can treat addiction, and alcohol use in Ireland. JAMA Network Open: Knowledge, Attitudes, and Beliefs About Opioid Use Disorder Treatment in Primary Care BBC...
2024-12-02
34 min
Addiction Medicine Journal Club
41-50 Round-Up
41-50. Round-Up Quick summaries of our last 10 (actually 11) articles. 41. Electronic Nicotine-Delivery Systems for Smoking Cessation42. Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures43. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge44 Association of Cannabis Use With Cardiovascular Outcomes Among US Adults45. Association of random and observed urine drug screening with long-term retention in opioid treatment programs46. Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial 47. Extended-Release Injection vs...
2024-11-18
1h 02
Addiction Medicine Journal Club
50. Kratom Journal Club
In episode 50 we discuss 3 articles about kratom.We are again joined by our friend Dr. Casey Grover from the Addiction Medicine Made Easy Podcast. Smith KE, Dunn KE, Rogers JM, Grundmann O, McCurdy CR, Garcia-Romeu A, Schriefer D, Swogger MT, Epstein DH. Kratom use as more than a "self-treatment". Am J Drug Alcohol Abuse. 2022 Nov 2;48(6):684-694. Hill K, Grundmann O, Smith KE, Stanciu CN. Prevalence of Kratom Use Disorder Among Kratom Consumers. J Addict Med. 2024 May-Jun 01;18(3):306-312. Broyan, V. R., Brar, J. K., All...
2024-11-04
53 min
Addiction Medicine Journal Club
49. Naltrexone/Bupropion for Methamphetamine Use Disorder
In episode 49 we discuss the 12-week follow-up data from the ADAPT-2 trial about using ER injectable naltrexone and bupropion for methamphetamine use disorder. Li MJ, Chau B, Belin T, Carmody T, Jha MK, Marino EN, Trivedi M, Shoptaw SJ. Extended observation of reduced methamphetamine use with combined naltrexone plus bupropion in the ADAPT-2 trial. Addiction. 2024 Jun 10. doi: 10.1111/add.16529. Epub ahead of print. PMID: 38856086. We also discuss fentanyl vaccines, and how easy it is to manufacture fentanyl. The Conversation: A new fentanyl vaccine looks promising – but treating drug addiction...
2024-10-21
37 min
Addiction Medicine Journal Club
Kratom: At Least It’s Not Fentanyl
In this episode we discuss kratom with our friend Dr. Casey Grover of the Addiction Medicine Made Easy podcast. Stay tuned for part 2 coming next, Kratom Journal Club. Tampa Bay Times: Deadly Dose Annals of Internal Medicine Kratom: An Emerging Issue for Research and Physician Education --- This episode is not eligible for CME, but other episodes offer category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Co-Host: Dr. Casey Grover Original theme music: composed and perfor...
2024-10-14
40 min
Addiction Medicine Made Easy | Fighting back against addiction
Kratom and the US Opioid Crisis: A Help or a Harm?
Unlock the complexities of Kratom, a substance both fascinating and misunderstood, as we promise to enrich your understanding with insights from Dr. Sonya Del Tredici and Dr. John Keenan of the Addiction Medicine Journal Club. Join us as we explore Kratom's dual identity as a stimulant and opioid-like substance, its traditional roots, and the reasons behind its rise in popularity. Despite its widespread use, many see Kratom as an herbal supplement rather than a drug, leading to an awareness gap among healthcare professionals. We stress the importance of recognizing Kratom's impact in the field of addiction medicine and why...
2024-10-14
39 min
Addiction Medicine Journal Club
48. Semaglutide and Alcohol Use Disorder
In episode 48 we discuss the association between semaglutide and alcohol use disorder. Wang, W., Volkow, N.D., Berger, N.A. et al. Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population. Nat Commun 15, 4548 (2024). The Journal of Addiction Medicine: The Efficacy of GLP-1 Agonists in Treating Substance Use Disorder in Patients We also discuss THC products that look like candy, a good podcast on targeted naltrexone, and perioperative opioids. The LA Times: Surgeons give patients too many opioids. A few simple steps could curb exce...
2024-10-07
35 min
Addiction Medicine Journal Club
47. Injectable Vs. Sublingual Buprenorphine for Fentanyl Use Disorder
In episode 47 we discuss the effectiveness of sublingual and injectable buprenorphine for patients with OUD, with and without fentanyl. Nunes EV, Comer SD, Lofwall MR, Walsh SL, Peterson S, Tiberg F, Hjelmstrom P, Budilovsky-Kelley NR. Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2417377. We also discuss the AMA’s Support of drug decriminalization, and the rise of alcohol-related health problems. New York Times: Oregon Is Recriminalizing Drugs. Here’s What Portl...
2024-09-23
35 min
Addiction Medicine Journal Club
46. High Dose Meds for Smoking Cessation
In episode 46 we discuss using high doses of varenicline and nicotine for smoking cessation. Cinciripini PM, Green CE, Shete S, Minnix JA, Robinson JD, Cui Y, Kim S, Kypriotakis G, Beneventi D, Blalock JA, Versace F, Karam-Hage M. Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial. JAMA. 2024 May 28; 331(20):1722-1731. We also discuss resources for safer substance use, and the recall of dangerous Diamond Shrooms. Yale Program in Addiction Medicine: Resources for Safer Injection and Substance Use San Fran...
2024-09-09
35 min
Addiction Medicine Journal Club
45. Urine Drug Screens and Treatment Retention
45. Urine Drug Screens and Treatment Retention In episode 45 we discuss urine drug screens and treatment retention. Michener PS, Knee A, Wilson D, Boama-Nyarko E, Friedmann PD. Association of random and observed urine drug screening with long-term retention in opioid treatment programs. Drug Alcohol Depend. 2024 Feb 1;255:111067. We also discuss storing injectable buprenorphine at room temperature and subliminal menthol in cigarettes. Sublocade Prescribing Information (Storage update top of page 40) Andre Luiz Oliveira da Silva, Lauren K. Lempert, Stanton A. Glantz. More than a “char...
2024-07-15
42 min
Addiction Medicine Journal Club
44. Cannabis and CV Outcomes
44. Cannabis and CV Outcomes In episode 44 we discuss the association between cannabis use and cardiovascular outcomes. Jeffers AM, Glantz S, Byers AL, Keyhani S. Association of Cannabis Use With Cardiovascular Outcomes Among US Adults. J Am Heart Assoc. 2024 Mar 5;13(5):e030178. doi: 10.1161/JAHA.123.030178. Epub 2024 Feb 28. We also discuss the DEA rescheduling cannabis, and the failure of the menthol ban. Department of Justice: Justice Department Submits Proposed Regulation to Reschedule Marijuana Stat News: Biden administration punts menthol cigarette rule indefinitely ---
2024-07-01
33 min
Addiction Medicine Journal Club
43. Alcohol Use Disorder Meds at Hospital Discharge
In episode 43 we discuss prescribing medication for alcohol use disorder at hospital discharge. Bernstein EY, Et al. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024 Mar 4;7(3):e243387. We also discuss grandparents raising grandchildren who’ve lost a parent to drug overdose, and how native peoples are using opioid settlement funds. Department of labor: Grandchildren Being Raised by Grandparents JAMA Psychiatry: Estimated Number of Children Who Lost a Parent to Drug Overdose in the US From 2011 to 2021 KFF News: Tr...
2024-06-17
34 min
Addiction Medicine Journal Club
42. The Protective Effect of Buprenorphine
In episode 42 we discuss how buprenorphine protects against fentanyl overdose. Zheng Dai, et al. Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures. Journal of Substance Use and Addiction Treatment, Volume 158, 2024. 209252, ISSN 2949-8759. We also discuss semaglutide for alcohol use disorder. Richards JR, et al. Significant Decrease in Alcohol Use Disorder Symptoms Secondary to Semaglutide Therapy for Weight Loss: A Case Series. J Clin Psychiatry. 2023 Nov 27;85(1):23m15068. --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES an...
2024-06-03
24 min
Addiction Medicine Journal Club
41. Vaping for Smoking Cessation
In episode 41 we discuss vaping for smoking cessation. Auer R, et al. Electronic Nicotine-Delivery Systems for Smoking Cessation. N Engl J Med. 2024 Feb 15;390(7):601-610. We also discuss the NarxCare addiction risk score and the recent increase in alcohol-related deaths. New York Times: Addiction Risk Scores Won’t Solve the Opioid Crisis CDC: Deaths from Excessive Alcohol Use — United States, 2016–2021 --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go...
2024-05-20
36 min
Addiction Medicine Journal Club
31-40 Round-Up
Quick summaries of Episodes 31-40. 31. Injection Drug Use Frequency Before and After Take-Home Naloxone Training 32. Trazodone for sleep disturbance in opioid dependent patients maintained on buprenorphine: A double blind, placebo-controlled trial 33. Non-fatal overdose risk associated with prescribing opioid agonists concurrently with other medication: Cohort study conducted using linked primary care, secondary care and mortality records 34. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl 35. Removal of Medicaid Prior Authorization Requirements and Buprenorp...
2024-05-06
1h 03
Addiction Medicine Journal Club
40. BZD Prescriptions and Overdose Risk
In this episode we discuss drug overdose after benzodiazepine prescriptions for anxiety and depression. Bushnell GA, et al. Drug overdose risk with benzodiazepine treatment in young adults: Comparative analysis in privately and publicly insured individuals. Addiction. 2023. We also talk about the war on recovery treatments and patients leaving the hospital against medical advice. STAT News: The War on Recovery Scientific American: Against Medical Advice: Another Deadly Consequence of Our Opioid Epidemic ---This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Mic...
2024-04-22
35 min
Addiction Medicine Journal Club
39. Opioid Abstinence and Cognitive Function
In this episode we discuss improvements in cognitive function with opioid abstinence. Kaur, G. Et Al. Effects of Abstinence From Opioid on Neuropsychological Performance in Men With Opioid Use Disorder: A Longitudinal Study. Journal of Addiction Medicine 17(5): p 557-562, 9/10 2023. We also talk about paramedics giving buprenorphine along with naloxone in the field, and the post-acute withdrawal syndrome. St. Louis Public Radio: Missouri pilot program trains EMS crews to give overdose victims addiction meds The Journal of Addiction Medicine: Post-Acute Withdrawal Syndrome ---------- This podc...
2024-04-08
31 min
Addiction Medicine Journal Club
Articles that Changed Our Practice - Part 2
In this episode we discuss 5 more articles that changed our addiction medicine practice. Chambers LC, et al. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl. JAMA Netw Open. 2023; 6(9):e2334540. September 2023. (Episode 34) Caponnetto, P., et al. Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial. BMC Med 21, 220 (2023). (Episode 29) Litwin AH, et al. The HERO Study Group. Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial. Lancet Gastroenterol Hepatol. 2...
2024-03-25
42 min
Addiction Medicine Journal Club
Articles that Changed Our Practice - Part 1
In this episode we discuss 5 articles that changed our addiction medicine practice. Mahdi Sheikh, et al. Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study. Ann Intern Med.2021;174:1232-1239. [Epub 27 July 2021]. (Episode 4) Santos GM, et al. Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial. Am J Psychiatry. 2022 Dec 1;179(12):915-926. Epub 2022 Oct 26. (Episode 20) Perry, Briana N. MD; et al. Buprenorphine-naloxone Versus Buprenorphine for Treatment of Opioid Use Disorder...
2024-03-11
38 min
Addiction Medicine Journal Club
38. Rehab vs. Meds vs. No Treatment
In episode 38 we discuss an article comparing different treatments (and no treatment) for opioid use disorder.Robert Heimer, Anne C. Black, Hsiuju Lin, Lauretta E. Grau, David A. Fiellin, Benjamin A. Howell, Kathryn Hawk, Gail D’Onofrio, William C. Becker. Receipt of Opioid Use Disorder Treatments Prior to Fatal Overdoses and Comparison to No Treatment in Connecticut, 2016-17. Drug and Alcohol Dependence. 2023.We also discuss stigma against patients with opioid use disorder who need surgery for endocarditis, the first American opioid addiction crisis after the Civil War, and banning me...
2024-02-26
34 min
Addiction Medicine Journal Club
37. Injectable Vs. Sublingual Buprenorphine
37. Injectable Vs. Sublingual BuprenorphineIn episode 37 we discuss an article comparing injectable and sublingual buprenorphine.Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial. Marsden, John et al. eClinicalMedicine, Volume 66, 102311 We also discuss new data on the teratogenicity of fentanyl, and a new genetic test to identify the risk for opioid use disorder.Genetics on Medicine Open: A novel syndrome associated with prenatal fentanyl exposure
2024-02-05
46 min
Addiction Medicine Journal Club
36. FOMO and Smartphone Use
In episode 36 we discuss an article about the mediators of problematic smartphone use.Christiane Arrivillaga, Caleb J. Hallauer, Christian Montag, Jon D. Elhai. Emotion dysregulation factors associated with problematic smartphone use severity: The mediating role of fear of missing out. Addictive Behaviors. Volume 143. 2023. https://doi.org/10.1016/j.addbeh.2023.107708We also discuss the National Survey on Drug Use and Health and Rite Aid’s bankruptcy.SAMHSA: Highlights from the 2022 National Survey on Drug Use and HealthSAMHSA: Results from the 2022 National Survey on Dr...
2024-01-15
31 min
Addiction Medicine Journal Club
35. Prior Auths and Buprenorphine
In episode 35 we discuss whether eliminating prior auths leads to more buprenorphine prescribing.Christine PJ, Larochelle MR, Lin L, McBride J, Tipirneni R. Removal of Medicaid Prior Authorization Requirements and Buprenorphine Treatment for Opioid Use Disorder. JAMA Health Forum. 2023;4(10):e233549.We also discuss buprenorphine diversion, and the lack of treatments for stimulant use disorder.Harm Reduction Journal: Examining buprenorphine diversion through a harm reduction lens: an agent-based modeling studyNBC news: Why are there no treatments for cocaine and meth addicti...
2024-01-01
37 min
Addiction Medicine Journal Club
34. 24 mg of Buprenorphine
In episode 24 we discuss prescribing 24 mg of buprenorphine daily.Chambers LC, Hallowell BD, Zullo AR, et al. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl. JAMA Netw Open. 2023;6(9):e2334540. September 2023. We also discuss why Rite Aid filed for bankruptcy, and the FDA ban on menthol cigarettes.From the NY Times: Rite Aid, Facing Slumping Sales and Opioid Suits, Files for BankruptcyFrom CNN: FDA takes ‘momentous’ step toward banning menthol cigarette...
2023-12-18
24 min
Addiction Medicine Journal Club
33. Polypharmacy and Overdose
In episode 33 we discuss overdose risk and polypharmacy: opioids, benzodiazepines, antipsychotics, and gabapentinoids.Domzaridou E, Carr MJ, Millar T, Webb RT, Ashcroft DM. Non-fatal overdose risk associated with prescribing opioid agonists concurrently with other medication: Cohort study conducted using linked primary care, secondary care and mortality records. Addiction. 2023 Aug 3.We also discuss treating HIV in primary care, and how eliminating prior auth barriers to buprenorphine does not increase prescribing.The MidAtlantic AIDS Education and Training CenterRemoval of Medicaid...
2023-12-04
35 min
Addiction Medicine Journal Club
32. Trazodone for Sleep in OUD
In episode 32 we discuss an article about trazodone for sleep in people with opioid use disorder on buprenorphine.Piyush Goyal, Dheeraj Kattula, Ravindra Rao, Roshan Bhad, Ashwani Kumar Mishra, Anju Dhawan. Trazodone for sleep disturbance in opioid dependent patients maintained on buprenorphine: A double blind, placebo-controlled trial. Drug and Alcohol Dependence. Volume 250. 2023. 110891. ISSN 0376-8716. We also discuss the decriminalization of psychedelics and treating HCV in primary care.From the LA Times: California moves to decriminalize use of magic mushrooms and other natural psychedelics
2023-11-20
26 min
Addiction Medicine Journal Club
31. Naloxone and IV Drug Use
31: We discuss an article about how naloxone training impacts IV drug use.Colledge-Frisby S, Rathnayake K, Nielsen S, et al. Injection Drug Use Frequency Before and After Take-Home Naloxone Training. JAMA Netw Open. 2023;6(8):e2327319. We also discuss gambling self-exclusion and which professions use the most drugs.From the Pennsylvania Gaming Control Board: Gambling Self-Exclusion From the CDC: Drug Overdose Mortality by Usual Occupation and Industry Two other podcasts on naloxone:The Addiction in Emergency...
2023-11-06
28 min
Addiction Medicine Journal Club
21-30 Round-Up
Quick summaries of Episodes 21-30.21. SOAT for OUD: Short-Acting Opioid Agonists for Opioid Use Disorder: Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder 22. Contingency Management for Coronary Artery Disease: High-risk Coronary Plaque Regression in Cash-based Contingency Management Intervention Among Cocaine Users With HIV-associated Subclinical Coronary Atherosclerosis23. Eat-Sleep-Console: ACT NOW Collaborative. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal24. Smoking Cessation and Mortality: Association Between Smoking, Smoking Cessation, and Mortality by Race, Ethnicity, and Sex Among US Adult...
2023-10-23
47 min
Addiction Medicine Journal Club
30. Race and MOUD
In episode 30 we discuss an article about racial differences in the receipt of medications for opioid use disorder.Barnett ML, Meara E, Lewinson T, Hardy B, Chyn D, Onsando M, Huskamp HA, Mehrotra A, Morden NE. Racial Inequality in Receipt of Medications for Opioid Use Disorder. N Engl J Med. 2023 May 11;388(19):1779-1789.We also talk about opioid poisonings among children under 6, and the Cannabis Users Restoration of Eligibility (CURE) Act.From the journal Pediatrics: Characteristics of Fatal Poisonings Among Infants and Young Children in...
2023-10-09
38 min
Addiction Medicine Journal Club
29. Vaping Cessation
In episode 29 we discuss an article about using varenicline and counseling for vaping cessation..Caponnetto, P., Campagna, D., Ahluwalia, J.S. et al. Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial. BMC Med 21, 220 (2023).In other vaping-related news:From NYSCSH: Vape pens that look like highlightersFrom the Surgeon General: Risk of e-cigarettes and how to take actionHow can you protect your kids (and other people’s kids): The Campaign for Tobacco-free kids----------This podcast of...
2023-09-25
33 min
Addiction Medicine Journal Club
28. Pain and Recovery
In episode 28 we discuss an article about pain and addiction recovery.Ajay Manhapra, Elina A. Stefanovics, Taeho Greg Rhee, Robert A. Rosenheck, Persistence of significant pain interference following substance use disorder remission: Negative association with psychosocial and physical recovery, Drug and Alcohol Dependence, Volume 232, 2022, 109339, ISSN 0376-8716, We also discuss top-selling flavored e-cigarette products, and Sweden becoming the first smoke-free country. Scripps News: Sweden Close to Becoming the Frist Smoke-Free Country in EuropeJAMA Network Open: Evaluation of statewide restrictions on...
2023-09-11
37 min
Addiction Medicine Journal Club
27. The First Opioid Prescription
In episode 27 we discuss an article about the risk of developing opioid use disorder after the first opioid prescription.Kendler, K., Lönn, S., Ektor-Andersen, J., Sundquist, J., & Sundquist, K. (2022). Risk factors for the development of opioid use disorder after first opioid prescription: A Swedish national study. Psychological Medicine, 1-9. From JAMA: Physicians’ actions to help end the nation’s drug-related overdose and death epidemic—and what still needs to be done. ---------This episode is eligible for CME credit from MICARES and Michigan State Universi...
2023-08-28
34 min
Addiction Medicine Journal Club
26. Addiction Survivors
26. We discuss a new conceptual model of addiction recovery.Pytell, J.D., Chander, G., Thakrar, A.P. et al. Pytell, J.D., Chander, G., Thakrar, A.P. et al. Does a Survivorship Model of Opioid Use Disorder Improve Public Stigma or Policy Support? A General Population Randomized Experiment. J GEN INTERN MED 38, 1638–1646 (2023).We also talk about choosing wisely in addiction medicine. What would be on your “Things we do for no reason” list?From the Journal of the Society of Hospital Medicine: Avoiding methadone for opioid withdra...
2023-08-15
36 min
Addiction Medicine Journal Club
25. High-dose Buprenorphine Induction
25. We discuss an article about high-dose buprenorphine induction.Herring AA, Vosooghi AA, Luftig J, et al. High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder. JAMA Netw Open. 2021;4(7):e2117128.From NPR: Drugmaker Mallinckrodt may renege on $1.7 billion opioid settlement----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn...
2023-07-17
31 min
Addiction Medicine Journal Club
24. Smoking Cessation and Mortality
24. We discuss updated data on the harms of smoking and the benefits of quitting.Thomson B, Emberson J, Lacey B, et al. Association Between Smoking, Smoking Cessation, and Mortality by Race, Ethnicity, and Sex Among US Adults. JAMA Netw Open. 2022;5(10):e2231480.We also discuss the drug supply shift from heroin to fentanyl, and how California wants to decriminalize psychedelics.CDC: Rapid Analysis of Drugs: A Pilot Surveillance System To Detect Changes in the Illicit Drug Supply To Guide Timely Harm Reduction Responses — Eight Syringe Serv...
2023-07-03
35 min
Addiction Medicine Journal Club
23. Eat-Sleep-Console
23. We discuss an article about the Eat-Sleep-Console approach to treat neonatal opioid withdrawal syndrome.Young LW, Ounpraseuth ST, et. al. ACT NOW Collaborative. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal. N Engl J Med. 2023 Apr 30. doi: 10.1056/NEJMoa2214470. Epub ahead of print. PMID: 37125831.We also share how even nematodes get the endocannabinoid munchies, and semaglutide helps rats with their binge-drinking. The conserved endocannabinoid anandamide modulates olfactory sensitivity to induce hedonic feeding in C. elegans Semaglutide reduces alcohol intake and relapse-like drinking in male and female...
2023-06-19
31 min
Addiction Medicine Journal Club
22. Contingency Management for Coronary Artery Disease
22. Contingency Management for Coronary Artery Disease22: We discuss an article about contingency management and the regression of coronary plaques in HIV+ cocaine users.Lai, Hong PhD; Bluemke, David A. MD; Fishman, Elliot K. MD; Gerstenblith, Gary MD; Celentano, David D. ScD; Treisman, Glenn MD; Foster, Parker MS; Mandler, Raul MD; Khalsa, Jag MS, PhD; Chen, Shaoguang MS; Bhatia, Sandeepan MD; Kolossváry, Márton MD; Lai, Shenghan MD. High-risk Coronary Plaque Regression in Cash-based Contingency Management Intervention Among Cocaine Users With HIV-associated Subclinical Coronary Atherosclerosis. Journal of Addiction Medicine 17(2):p 14...
2023-06-05
28 min
Addiction Medicine Journal Club
21. SOAT for OUD: Short-Acting Opioid Agonists for Opioid Use Disorder
21: We discuss an article about using short-acting opioids to treat opioid use disorder in the hospital.Thakrar, A.P., Uritsky, T.J., Christopher, C. et al. Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder. Addict Sci Clin Pract 18, 13 (2023). We also discuss compulsory addiction treatment:Why involuntary treatment for addiction is a dangerous ideaMy Son Was Addicted and Refused Treatment. We Needed More Options.Juul is getting sued (too bad, so sad):...
2023-05-22
37 min
Addiction Medicine Journal Club
What We Learned at ASAM2023
What We Learned at ASAM2023In this episode, we share what we learned at the 2023 American Society of Addiction Medicine Conference.Some links from the conference that you might like:Curbsiders Addiction Medicine PodcastToxIC: Toxicology Investigators ConsortiumDrugsData from the Erowid CenterCESAR: Center for Substance Use, Addiction, and Health Research ---------Episode Credits: Original theme music: composed and performed by Benjamin Kennedy Audio production: Erin McCue Video production: Paul Kennedy Executive P...
2023-05-08
41 min
Addiction Medicine Journal Club
11-20 Round-up
11-20 Round-upSuper busy? Here are quick summaries of the last 10 articles.Article list:11. Impact of wine bottle and glass sizes on wine consumption at home: a within- and between- households randomized controlled trial12. Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities13. Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study14. Effects of Early Life Trauma on Risks for Adult Opioid Use Disorder Are Mediated by Stress and Occur Independent of...
2023-04-24
35 min
Addiction Medicine Journal Club
20. Targeted Naltrexone for Binge Drinking
20. Targeted Naltrexone for Binge DrinkingIn episode 20 we discuss an article about taking naltrexone as needed to reduce binge drinking among sexual and gender minority men.Santos GM, Ikeda J, Coffin P, Walker J, Matheson T, Ali A, McLaughlin M, Jain J, Arenander J, Vittinghoff E, Batki S. Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial. Am J Psychiatry. 2022 Dec 1;179(12):915-926. Epub 2022 Oct 26. We also discuss the recent reduction in the number of o...
2023-04-10
31 min
Addiction Medicine Journal Club
19. Patients’ Goals in Treatment
19. Patients’ Goals in TreatmentIn episode 19 we discuss an article about what is most important to patients in treatment for opioid use disorder.Reed, M.K., Smith, K.R., Ciocco, F. et al. Sorting through life: evaluating patient-important measures of success in a medication for opioid use disorder (MOUD) treatment program. Subst Abuse Treat Prev Policy 18, 4 (2023). Also, here are the DEA’s proposed telemedicine regulations, and we encourage you to submit public comments by 3/31/23.1. Telemedicine prescribing of controlled substances when...
2023-03-29
32 min
Addiction Medicine Journal Club
18. Treating HCV in People Who Inject Drugs
In episode 18 we discuss the Hepatitis C Real Option (HERO) Study about two different models of HCV treatment in people who inject drugs. Litwin AH, Lum PJ, Taylor LE, Mehta SH, Tsui JI, Feinberg J, Kim AY, Norton BL, Heo M, Arnsten J, Meissner P, Karasz A, Mckee MD, Ward JW, Johnson N, Pericot-Valverde I, Agyemang L, Stein ES, Thomas A, Borsuk C, Blalock KL, Wilkinson S, Wagner K, Roche J, Murray-Krezan C, Anderson J, Jacobsohn V, Luetkemeyer AF, Falade-Nwulia O, Page K; HERO Study Group. Patient-centred models of hepatitis C treatment for people who i...
2023-03-13
40 min
Addiction Medicine Journal Club
17. Bup-nalox vs. Bup in Pregnancy
In episode 17 we discuss buprenorphine-naloxone vs. buprenorphine alone in pregnancy.Perry, Briana N. MD; Vais, Simone MD; Boateng, Jeffery O. MBchB, MPH; Jain, Mayuri MPH; Wachman, Elisha M. MD; Saia, Kelley A. MD. Buprenorphine-naloxone Versus Buprenorphine for Treatment of Opioid Use Disorder in Pregnancy. Journal of Addiction Medicine 16(6):p e399-e404, 11/12 2022.We also discuss opioid-induced urinary retention, and the legalization of psilocybin in Oregon for treatment of alcohol use disorder and depression.Guy M. Goodwin, et. al. Single-Dose Psilocybin for a Treatment-Resistant Episode of...
2023-02-27
36 min
Addiction Medicine Journal Club
16. Treating Opioid Use Disorder in Jail
16. Treating Opioid Use Disorder in JailIn episode 16 we discuss an article about in-jail medication for opioid use disorder and recidivism.Elizabeth A. Evans, Donna Wilson, Peter D. Friedmann. Recidivism and mortality after in-jail buprenorphine treatment for opioid use disorder. Drug and Alcohol Dependence, Volume 231, 2022, 109254, ISSN 0376-8716.Scott, C.K., Grella, C.E., Dennis, M.L. et al. Availability of best practices for opioid use disorder in jails and related training and resource needs: findings from a national interview study of jails in heavily...
2023-02-13
28 min
Addiction Medicine Journal Club
15. Buprenorphine vs. Methadone in Pregnancy
In episode 15 we discuss buprenorphine vs. methadone in pregnancy.E.A. Suarez, K.F. Huybrechts, L. Straub, S. Hernández‑Díaz, H.E. Jones, H.S. Connery, J.M. Davis, K.J. Gray, B. Lester, M. Terplan, H. Mogun, and B.T. Bateman. Buprenorphine versus Methadone for Opioid Use Disorder in Pregnancy. N Engl J Med 2022; 387:2033-2044. Bruzelius E, Martins SS. US Trends in Drug Overdose Mortality Among Pregnant and Postpartum Persons, 2017-2020. JAMA. 2022;328(21):2159–2161. We also discuss opioid use disorder in our geriatric patients, and opening a new bu...
2023-01-30
34 min
Addiction Medicine Journal Club
14. Early Life Trauma and Opioid Use Disorder
In episode 14 we discuss the connection between early life trauma, depression, anxiety, stress, and opioid use disorder.Effects of Early Life Trauma on Risks for Adult Opioid Use Disorder Are Mediated by Stress and Occur Independent of Depression and Anxiety. Dunn, Kelly E. PhD, MBA; Turner, Gavin M. BS; Oswald, Lynn M. PhD. Journal of Addiction Medicine: 11/12 2022 - Volume 16 - Issue 6 - p 709-715 doi: 10.1097/ADM.0000000000001011We also discuss an opinion piece on AMA discharges and the new fentanyl vaccine.Retiring the “Against Medical Adv...
2023-01-09
29 min
Addiction Medicine Journal Club
13. Prescription Opioids and Cognitive Decline
In episode 13 we discuss opioids and cognitive changes in older adults.Warner, NS, Hanson, AC, Schulte, PJ, Habermann, EB, Warner, DO, Mielke, MM. Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study. J Am Geriatr Soc. 2022; 1- 12. doi:10.1111/jgs.18030 https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.18030----------We also discuss the new (and old) CDC opioid prescribing guidelines.----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go...
2023-01-02
25 min
Addiction Medicine Journal Club
12. Methamphetamine and Opioid Overdose in Rural Communities
In episode 12 we discuss overdoses related to methamphetamine and opioid use in rural areas.Korthuis PT, Cook RR, Foot CA, et al. Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities. JAMA Netw Open. 2022;5(8):e2226544. doi:10.1001/jamanetworkopen.2022.26544 August 2022Rural Opioid Initiative----------We also discuss building community in addiction medicine. ASAM Connect Addiction Medicine Doctors Facebook group ASAM annual meeting List of available ECHOs ----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for...
2022-12-19
31 min
Addiction Medicine Journal Club
11. Wine Bottle and Wineglass Size
In episode 11 we discuss an article about the impact of wine bottle and glass size on consumption.Mantzari, E, Ventsel, M, Ferrar, J, Pilling, MA, Hollands, GJ, Marteau, TM. Impact of wine bottle and glass sizes on wine consumption at home: a within- and between- households randomized controlled trial. Addiction. 2022. ----------We discuss non-abstinence-based resources for addressing unhealthy alcohol use Rethinking Drinking Moderation Management Dry January Alcohol Harm Reduction Tips We also talk about calling to check in on patients who have been lost to follow-up. ----------Th...
2022-12-05
28 min
Addiction Medicine Journal Club
1-10. Round-up
Short on time? In this episode we give you quick summaries of articles 1-10. Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease Analysis of Stimulant Prescriptions and Drug-Related Poisoning Risk Among Persons Receiving Buprenorphine Treatment for Opioid Use Disorder Association of Dose Tapering With Overdose or Mental Health Crisis Among Patients Prescribed Long-term Opioids Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults: A Randomized Clinical Trial Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol...
2022-11-21
44 min
Addiction Medicine Journal Club
10. Buprenorphine Tapering
In episode 10 we discuss an article about buprenorphine tapering.Bozinoff N, Men S, Kurdyak P, Selby P, Gomes T. Prescribing Characteristics Associated With Opioid Overdose Following Buprenorphine Taper. JAMA Netw Open. 2022;5(9):e2234168. ----------Take a look at Riggs, KR, DeRussy, AJ, Leisch, L, et al. Sensitivity of health records for self-reported nonfatal drug and alcohol overdose. Am J Addict. 2022; 1- 6. We also discuss the federal government’s plan to provide care for people with opioid use disorder during pregnancy. Watch Mat...
2022-11-07
35 min
Addiction Medicine Journal Club
9. Psilocybin for Alcohol Use Disorder
In episode 9 we discuss psilocybin for treating alcohol use disorder.Bogenschutz MP, Ross S, Bhatt S, et al. Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022;79(10):953–962.----------We talk about Wal-Mart and CVS not filling some telemedicine prescriptions.We also discuss gabapentin involvement in overdose deaths and the efficacy of gabapentin for neuropathic pain.Mattson CL, Chowdhury F, Gilson TP. Notes from the...
2022-10-24
40 min
Addiction Medicine Journal Club
8. Opioid Tapering and Risk of Suicide and Overdose
In episode 8 we discuss the article about opioid tapering and discontinuation, and the risks of suicide and overdose.Larochelle MR, Lodi S, Yan S, Clothier BA, Goldsmith ES, Bohnert ASB. Comparative Effectiveness of Opioid Tapering or Abrupt Discontinuation vs No Dosage Change for Opioid Overdose or Suicide for Patients Receiving Stable Long-term Opioid Therapy. JAMA Netw Open. 2022;5(8):e2226523.We also discuss the recent Ruan vs. United States supreme court decision about pill mills.----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES a...
2022-10-10
35 min
Addiction Medicine Journal Club
7. Treating Opioid and Polysubstance Use Disorders
In Episode 7 we discuss treating opioid use disorder with co-occurring polysubstance use.Xu KY, Mintz CM, Presnall N, Bierut LJ, Grucza RA. Comparative Effectiveness Associated With Buprenorphine and Naltrexone in Opioid Use Disorder and Cooccurring Polysubstance Use. JAMA Netw Open. 2022;5(5):e2211363. 2022 Aug 3. We also discuss the Society of Hospital Medicine’s new consensus statement about management of opioid use disorder in the hospital, and hepatotoxicity from depot buprenorphine.Calcaterra SL, Et. Al. Management of opioid use disorder and associated conditions among hospitalized adults: A Co...
2022-09-26
34 min
Addiction Medicine Journal Club
6. A BZD-Sparing Alcohol Withdrawal Protocol
In episode 6 we discuss a benzodiazepine-sparing alcohol withdrawal protocol.Smith JT, Sage M, Szeto H, et al. Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol Withdrawal Order Set in an Integrated Health Care System. JAMA Netw Open. 2022;5(2):e220158. 2022 Feb 2.We also discuss long-term outcomes from a primary-care based MAT clinic, and the movement to deregulate methadone and expand access.Cope K, DeMicco J, Salib J, Michael M, Yakoub P, Daoud K, Cope R. Three-year Retention Rates With Office-based Treatment of Buprenorphine for Opioid Use Disorder i...
2022-09-12
27 min
Addiction Medicine Journal Club
5. Clinical Effects of Medical Marijuana Cards
Episode 5 discusses the clinical effects of getting a medical marijuana card.Gilman JM, Schuster RM, Potter KW, et al. Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(3):e222106. If you want an introduction on how to manage medical marijuana in primary care, listen to this awesome episode from The Curbsiders. We also discuss ASAM Connect, and how to get more PCPs into addiction medicine.If y...
2022-08-29
31 min
Addiction Medicine Journal Club
4. Smoking Cessation After Lung Cancer Diagnosis
Episode 4 discusses the benefits of smoking cessation after a diagnosis of lung cancer.Mahdi Sheikh, Anush Mukeriya, Oxana Shangina, et al. Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study. Ann Intern Med.2021;174:1232-1239. [Epub 27 July 2021].We also talk about whether or not increased buprenorphine prescribing will lead patients to be placed on it inappropriately, and some of the hurdles faced when trying to prescribe medications for opioid use disorder in the hospital.To make sure you’re prescribing buprenorphine co...
2022-08-15
25 min
Addiction Medicine Journal Club
2: Prescribing Stimulants for Patients on Buprenorphine
In episode 2 we discuss the safety of prescribing stimulants for patients receiving buprenorphine.Article Citation: Mintz CM, Xu KY, Presnall NJ, et al. Analysis of Stimulant Prescriptions and Drug-Related Poisoning Risk Among Persons Receiving Buprenorphine Treatment for Opioid Use Disorder. JAMA Netw Open. 2022;5(5):e2211634. doi:10.1001/jamanetworkopen.2022.11634We also discuss marketing of flavored tobacco and nicotine products to children.----------This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make...
2022-08-02
26 min
Addiction Medicine Journal Club
3. Opioid Tapering and Overdoses and Mental Health Crises
In episode 3 we discuss the risks of tapering for patients on long-term, high-dose opioids.Article citation: Agnoli, A., Xing, G., Tancredi, D. J., Magnan, E., Jerant, A., & Fenton, J. Association of Dose Tapering With Overdose or Mental Health Crisis Among Patients Prescribed Long-term Opioids. JAMA, 326(5), 411–419. August 3, 2021.We also discuss how to get your DEA waiver to prescribe buprenorphine in just 5 minutes.If you want to start prescribing buprenorphine right away take a look at the SAMHSA quick-start guide, or the ASAM one-hour mini-course.----------This podcast offers category 1 and MATE...
2022-08-02
37 min
Addiction Medicine Journal Club
1. The Cardiovascular Effects of Alcohol
In Episode 1 we discuss the article “Association of Habitual Alcohol Intake with Risk of Cardiovascular Disease,” a reexamination of the question of how alcohol intake is related to cardiovascular outcomes, and whether or not the J-curve for risks of alcohol intake actually exists.Article citation: Biddinger KJ, Emdin CA, Haas ME, et al. Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease. JAMA Netw Open. 2022;5(3):e223849. doi:10.1001/jamanetworkopen.2022.3849.We also discuss xylazine as an additive to illicit opioids, and the possible FDA ban on menthol and flavored tobacco produ...
2022-07-04
31 min