Shows
Base by Baseđïž 74: Benchmarking T Cell ReceptorâEpitope Predictors with ePytope-TCRđïž Episode 74: Benchmarking T Cell ReceptorâEpitope Predictors with ePytope-TCR𧏠In this episode of PaperCast Base by Base, we explore a unified computational framework that integrates and benchmarks 21 T cell receptorâepitope binding prediction models to evaluate their performance on viral epitope repertoires and deep mutational scans.đ Study Highlights:The authors developed ePytope-TCR, which standardizes 18 general and three categorical prediction methods into a single interoperable platform compatible with common TCR repertoire formats. They assessed model performance on 638 epitope-specific TCRs from single-cell datasets and found that only a few predictors achieved moderate accuracy, exhibiting strong biases toward frequently studied epitope...2025-07-1320 min
On AIRR - Immune receptors in the clinicOn AIRR 18: From single-chain TCR sequencing to paired high-throughput methods with Paul ThomasIn this episode of On AIRR, Dr. Paul Thomas, reviews advances in the field of TCR sequencing. Dr. Thomas is a faculty member in the Department of Immunology of St. Jude Childrenâs Research Hospital. His work has advanced our understanding of innate and adaptive immune responses and TCR specificity with a focus on responses to viral infections.
In Episode 18 of On AIRR, Dr. Thomas shares his journey from immunoparasitology to pioneering TCR repertoire sequencing. He began his scientific career studying innate immune responses to parasites during his graduate work in immunoparasitology. Motivated by a desire to us...2025-06-0946 min
Beyond Biotech - the podcast from LabiotechTCR-NK: A novel cell therapy transforming cancer treatmentAre TCR-NK treatments the next big thing in cell therapies for cancer patients?As biotechs and pharma companies continue to innovate to address patient needs in oncology, T-cell receptor therapies, or TCR-Ts, are attracting significant interest and investment. There are already some promising results for TCR-Ts tackling solid tumors â but one Norwegian biotech is taking a slightly different track.This week, we sit down with Namir Hassan, CEO of Zelluna, a company with a mission to eliminate solid cancers by pioneering the development of T cell receptor guided natural killer, or TCR-NK, cell th...2025-05-0234 min
tcr!Refresh the BatteriesRefresh the Batteries by tcr!2025-01-2802 min
tcr!Orchestra FantastikOrchestra Fantastik by tcr!2024-10-3004 min
tcr!confront your feelingsconfront your feelings by tcr!2024-09-1903 min
tcr!soundtrack 1936soundtrack 1936 by tcr!2024-09-1912 min
tcr!the crowd almost went wildthe crowd almost went wild by tcr!2024-09-1901 min
tcr!space drift sunshinespace drift sunshine by tcr!2024-09-1805 min
tcr!steam locomotive musicalsteam locomotive musical by tcr!2024-09-0506 min
tcr!you're too good for meyou're too good for me by tcr!2024-09-0504 min
tcr!pandemic violinspandemic violins by tcr!2024-09-0403 min
tcr!slow mo milkweedslow mo milkweed by tcr!2024-08-3003 min
tcr!house burning in black and whitehouse burning in black and white by tcr!2024-08-3001 min
tcr!birds with pianobirds with piano by tcr!2024-08-3005 min
AutoFM Programa del Motor y CochesAnalizamos como es la categorĂa de turismos de circuito TCR.Extracto del programa emitido en Onda Cero MS los jueves a las 19:20.
Qué es el TCR?
-Se trata de un concepto de automovilismo de orden global. Tiene un Mundial avalado por la FIA y distintos certĂĄmenes regionales y nacionales. En total hay 35 campeonatos que utilizan este concepto.
-El concepto TCR fue creado por el italiano Marcello Liotti en 2014 con el objetivo de crear un reglamento que garantizara costos razonables, competitividad entre las marcas y buen espectĂĄculo.
-Una de las claves fue la similitud de los autos de pista con los de calle, saliendo de la tendencia hacia los pro...2024-07-2927 min
S&S On Biotech3.9 The slow rise of TCR-T therapyWhen the first chimeric antigen receptor T-cell (CAR-T) therapy was approved in 2017, there was a general expectation that T-cell receptor T-cell (TCR-T) therapies would follow shortly afterwards and would greatly expand the range of addressable antigens. Despite considerable efforts, CAR-T therapies are still limited to haematological cancers expressing extracellular antigens, such as CD19 or B-cell maturation antigen (BCMA). Autologous TCR-T therapies can be engineered to target intracellular as well as extracellular peptide antigens presented on the cell surface by human leukocyte antigens (HLAs) and can be more readily used in solid tumors as well as in haematological c...2024-07-2936 min
tcr!awayaway by tcr!2023-10-2904 mintcr!byebye by tcr!2023-10-2904 mintcr!13 flowers13 flowers by tcr!2023-10-2905 mintcr!vomitvomit by tcr!2023-10-2905 min
tcr!tap dancetap dance by tcr!2023-10-2904 mintcr!concerto 9.12 w beezconcerto 9.12 w beez by tcr!2023-10-2903 mintcr!cold jazz fushioncold jazz fushion by tcr!2023-10-2907 mintcr!2laVe2laVe by tcr!2023-10-2904 mintcr!an alternaivean alternaive by tcr!2023-10-2904 min
tcr!generate.bgenerate.b by tcr!2023-10-2902 mintcr!bastard.bbastard.b by tcr!2023-10-2907 min
Science SocietyUnmasking Leukemia: The Role of MHC:TCR Signaling with Dr. LaffeyThis episode delves into the cutting-edge research of Dr. Laffey, who has been investigating the role of Major Histocompatibility Complex:T cell antigen receptor (MHC:TCR) signaling in the development of T cell tumors. While this signaling pathway is crucial for T cell development and immune responses, it can also trigger the formation of T cell tumors under abnormal conditions.Dr. Laffey's research focuses on a low-frequency progenitor cell population known as Early αÎČ TCR+ Double-Negative (EADN) cells. Present in both mice and humans, these cells can transform into thymic leukemia. His work has shown that EADN cells do...2022-09-091h 47
tcr! diaries - podcastBack to regular life
content: Apr 19, 2019 · podcast: Jul 21, 2022
Audio (MP3): 20190419 - Back to regular life
Do you know what I really hate?
When somebody is being over-the-top nice after theyâve fucked something up.
Do you know what I really like?
When someone offers up a sincere apology and then gets on with the day.
Own it. Regret it. Forget it.
Take five minutes, have a real conversation, and then go back to regular life.
If I donât acknowledge I can come across like an unsym...2022-07-2100 min
The Creature ReportTCR_VPAL-ARCHIVAL_RECORDING_1023_SUBJECT1733CHARLES_SUBJECT964ADDISON_MISSINGSee you next week, Anchor.
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The Creature Report Documentation & Archival Assistant!
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tcr! diaries - podcastI only fought with the police once
content: Aug 22, 2018 · podcast: Sep 8, 2021
Audio (MP3): 20180822 - I only fought with the police once
I only fought with the police once and there was only one of them. And it was 3 in the afternoon. And I was drunk and feisty. And then he tackled my 19 year old self in an alley and one side of my face ended up in some gravel. And then I went to jail with a swollen eye. And got to spend the rest of the evening sobering up.
About 9pm or so and no longer drunk, I d...2021-09-0900 min
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2021-08-1409 min
tcr! diaries - podcastMiracles are seen in light
content: Apr 27, 2018 · podcast: May 6, 2021
Audio (MP3): 20180427 - Miracles are seen in light
I fall short in life.
Thatâs not a judgment call or me being hard on myself. It just is. Iâm just another guy wandering around aimlessly doing my bestâŠand sometimes doing my least.
Struggling to maintain that non-mistake-making state only makes my life harder. Letting that struggle go gave me so much more free time to enjoy life and the company of my fellow humans.
Well, I guess I never really expecte...2021-05-0600 min
The Cultural Reset (TCR)An Interview with DEMIE CAO - 'The Cultural Reset' | Artist Interview Series - Episode #16This weekâs episode of The Cultural Resetâs Artist Interview Series sees TCRâs Nick Lee and Shay Ervin speaking to Chinese-American songwriter/performer Demie Cao aka âDemie The Destroyerâ. In this discussion, Demie reflects on her career beginningsâfrom her stint in ballet and K-Pop to her current love of hip-hop and live performanceâand her thoughts on the branding limitations put on AAPI artists navigating the music industry.
...
The Cultural Reset is a platform designed to uplift the voices of POC and LGBTQ+ artists through album reviews, artist interviews, and curated playlists. To see more of...2021-05-0342 min
The Cultural Reset (TCR)An Interview with JASTIN ARTIS - 'The Cultural Reset' | Artist Interview Series - Episode #15In this newest entry of The Cultural Resetâs Artist Interview Series, TCRâs Nick Lee and Shay Ervin speak to DMV artist, Jastin Artis about his mission as an artist and his perspective on the expectations of artists in the music industry. From his thoughts on the industryâs treatment of genre-bending to his advice for all artistsâboth younger and matureânavigating the industry, Jastin shows the world his vision to reset the culture of music.
...
The Cultural Reset is a platform designed to uplift the voices of POC and LGBTQ+ artists through album revi...2021-04-2252 min
The Cultural Reset (TCR)An Interview with ROB MURAT - 'The Cultural Reset' | Artist Interview Series - Episode #14This latest entry of The Cultural Resetâs Artist Interview Series sees TCRâs Nick Lee and Shay Ervin speak to musician and Netflixâs âOn My Blockâ actor, Rob Murat. In an especially thought-provoking discussion, Rob and the team break down the differences between âinclusionâ in TV/Film vs. music and the importance of creating a lasting space for people of color in entertainment. From his perspective on âcreative trailblazingâ to his advice on navigating creative industries, Robâs conviction to maintaining his integrity shines through in this intimate conversation.
...
The Cultural Reset is a platform design...2021-04-1437 min
tcr! diaries - podcastNobody can fuck with you
content: Feb 12, 2018 · podcast: Mar 24, 2021
Audio (MP3): 20180212 - Nobody can fuck with you
Remember that one time when you were younger? When nobody could fuck with you?
Because everything had fallen into place. Because all the dots connected. Maybe your best friend was there.
It doesnât matter who you were with or how or when you got there. But that was it.
That was the moment when you rose above the bullshit and realized you were more than what you had always felt. It was like you...2021-03-2400 min
The Cultural Reset (TCR)An Interview with FELISHA GEORGE-'The Cultural Reset' | Artist Interview SeriesContinuing our programming for Womenâs History Month 2021, TCRâs Creator and Editor-in-Chief, Nick Lee, and Assistant Director, Shay Ervin, spoke with rapper and bonafide âWord Magicianâ, Felisha George. As an alum of Netflixâs Rhythm and Flow, Felisha George speaks about her experience on the show as well as her personal journey as a queer-female artist navigating the hip-hop genre. In an intimate discussion, George touches on the importance of control over oneâs brand as a woman and her thoughts on the unrealistic standards placed on women in rap-music.
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Support this podcast: https://anchor.fm/the-cultural...2021-03-1944 min
The Cultural Reset (TCR)An Interview with TYLER SIMONE-'The Cultural Reset' | Artist Interview SeriesIn honor of Womenâs History Month, this installment of The Cultural Resetâs Artist Interview Series sees TCRâs Nick Lee and Shay Ervin sit down with Tyler-Simone Molton, the lead singer of new wave/punk band Lesibu Grand. In an enlightening discussion, Tyler touches on the very personal inspiration behind her artistry as well as her dedication to authentic self-expression as a black woman in the music industry and her love of the unconventional.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2021-03-0337 min
The Cultural Reset (TCR)An Interview with NIAMBI RA-'The Cultural Reset' | Artist Interview SeriesIn this newest installment of The Cultural Reset's Artist Interview series, Creator Nick Lee and Assistant Director, Shay Ervin, sit down with Afro-futurist rapper, singer/songwriter Niambi Ra. A queer, black woman navigating a music career in Hip-Hop, Niambi speaks to TCR on the importance of artistic mentorship for artists of color, how her creative instinct intertwines with social activism, and remaining a music change-maker despite industry pressures for conformity.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2021-02-281h 14
The Cultural Reset (TCR)An Interview with MAYA J-'The Cultural Reset' | Artist Interview SeriesThe Cultural Reset kicks off Black History Month with an intimate interview with singer and actress Maya J. TCRâs Nick Lee and Shay Ervin sat down with Maya to discuss her new single âTroubleâ as well as her experience navigating the ups and downs of the entertainment industry as a female artist. From her unique perspectives on artist-label relationships to her pledge to always create outside of the box, Maya dishes on the importance of maintaining artistic integrity in an era of oversaturation in music.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2021-02-0345 min
The Cultural Reset (TCR)An Interview with MDL CHLD-'The Cultural Reset' | Artist Interview SeriesIn another eye-opening entry of The Cultural Resetâs Artist Interview Series, TCRâs Nick Lee and Shay Ervin, sat down with Artist/ASL Interpreter/Tarot Reader Chris Corsini, AKA MDL CHLD, to chat about music inclusivity for deaf audiences. In an incredibly compelling discussion, Chris opens up about his efforts to create art with deaf people in mind, his mission to revolutionize the industry for deaf music-lovers, and the industry disparities that exclude the deaf from fully enjoying live performances.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2021-01-2746 min
The Cultural Reset (TCR)An Interview with MEL SEMĂ-'The Cultural Reset' | Artist Interview SeriesA former contestant on The Voice: Spain and a multi-talented, classically trained musician, The Cultural Reset's Artist Interview Series is pleased welcome Mel SemĂ© to the roster. In a beautifully vulnerable interview, TCR's leads Nick Lee and Shay Ervin spoke with Mel about his childhood musical roots, the story of his mother's passing, his spontaneous artistic process and navigating the music industry as an independent artist.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2021-01-1345 min
tcr! diaries - podcastSteam Locomotive Musical
content: Jan 11, 2021
Video (MP4): 20210111 - Steam Locomotive Musical
Audio (MP3): 20210111 - Steam Locomotive Musical
Here we have a 1930s steam locomotive with drums, an upright bass, a couple of pianos, and a string section. The original video was over 18 minutes long so I chopped and rearranged to fit the music I put together. I guess this is the kinda thing I do in a pandemic.
I had originally planned for the music to go with some winter driving footage but that didnât pan out. When I came across Ne...2021-01-1100 min
The Cultural Reset (TCR)An Interview with LEX-'The Cultural Reset' | Artist Interview SeriesThis empowering entry of The Cultural Reset's Artist Interview Series sees TCR heads Nick Lee and Shay Ervin speaking with genre-bending vocalist and musician, LEX. In a beautifully revealing interview, LEX speaks about the intention behind her newest album release 'Bits and Pieces' and the personal tragedy that inspires her on her path toward self-actualization and awareness.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2021-01-0945 min
tcr! diaries - podcastHouse Burning in Black and White
content: Dec 30, 2020 · podcast: Jan 1, 2021
Audio (MP3): 20201229 - House Burning in Black and White
Video (MP4): 20201229 - House Burning in Black and White
A few piano melodies while a house burns in black and white đčđ„đ
Reminds me of the lower end of the Peanuts theme in certain parts.
#diariespodcast #diariesvideo
JFK Clone High
· Dec 30, 2020 at 4:44 pm
Hey is it okay if I use this video on my channel? Itâs gonna be the same thing but a different shade
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tcr! diaries - podcastPandemic Violins
content: Dec 26, 2020
Video (MP4): 20201226 - Pandemic Violins
Audio (MP3): 20201226 - Pandemic Violins
It's winter in a pandemic. It's Christmas time. I'm on vacation. I sit and write and record music. After listening to The Beatles sing about Eleanor Rigby on a two hour loop, I got hooked on violins stabbing and stomping about. The music sounds best with headphones.
Nothing happens in the video. I needed something visual because most of the social medias don't do just audio. The footage is public domain and fairly boring.
đ¶đ» #diariespodcast #diarie...2020-12-2700 min
The Cultural Reset (TCR)An Interview with SHENNA-'The Cultural Reset' | Artist Interview SeriesA new addition to The Cultural Reset's Artist Interview Series, indie-pop sensation Shenna sits down with TCR's Nick Lee and Shay Ervin for a lively discussion of her career journey. From moving to NYC at the age of 17 to reinventing the pop genre for women of color, Shenna gives TCR an in-depth rundown of how she is unapologetically breaking down barriers in music.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2020-12-1237 min
The Cultural Reset (TCR)An Interview with ARIA WUNDERLAND-'The Cultural Reset' | Artist Interview SeriesThis week's entry of The Cultural Reset's Artist Interview series sees Nick Lee and Shay Ervin sit down with Alternative-Pop revolutionary Aria Wunderland. Aria joins TCR to discuss how quarantine has shaped her music-making process, the industry stereotypes used to stifle creatives, and how independent artists are working to reset the music industry's landscape.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2020-12-0544 min
tcr! diaries - podcastBirds with piano
content: Nov 27, 2020
Audio (MP3): 20201127 - Birds with piano
Video (MP4): 20201127 - Birds with piano
If you need to relax after your Black Friday, please enjoy a little piano and birds in my bird bath. Being November in Illinois the birds won't get to do this much longer.
#diariespodcast #diariesvideo #naturerocks đč đ
alps
· Nov 27, 2020 at 8:26 pm
Iâve been getting 3 kinds of woodpeckers going to my feeder then bluejays, and cards. I could watch all day. đŻ
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...2020-11-2800 min
The Cultural Reset (TCR)An Interview with JAZZY MEJIA-'The Cultural Reset' | Artist Interview SeriesThis installation of The Cultural Reset's Artist Interview Series turns its focus to Pop/R&B singer/producer Jazzy Mejia. A teen icon and former member of internationally renown girl-group G.R.L., Jazzy Mejia sat down with TCR's Nick Lee and Shay Ervin to discuss her complicated transition from girl-group stardom to independent artist, the loved ones that inspire her creative process and growing up in and navigating the music industry as a woman of color.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2020-11-2142 min
The Cultural Reset (TCR)An Interview with NADIA TEHRAN-'The Cultural Reset' Artist Interview SeriesIn a new, particularly intimate entry of The Cultural Reset's Artist Interview Series, TCR's Creator/EIC Nick Lee, and Assistant Director, Shannon (Shay) Ervin, sat down with Iranian-Swedish rapper and songwriter, Nadia Tehran. Known for the personal and political themes that govern her work, Nadia joins TCR to deconstruct her most-recent album 'Dozakh: All Lovers Hell' as well as discuss her artistic inspiration, her creative paths, and her experience as a woman of color navigating the injustices of the music industry.
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Support this podcast: https://anchor.fm/the-cultural-reset/support2020-11-1429 min
tcr! diaries - podcastSlow Mo Milkweed
content: Nov 9, 2020
Video (MP4): 20201108 - Slow Mo Milkweed
Audio (MP3): 20201108 - Slow Mo Milkweed
On weekends when I don't have Maggie I often pretend like I'm a cinematographer who knows how to play the piano.
I also had Milkweed seeds all over my face when I was done.
đč đ„ #diariespodcast #diariesvideo
gracey
· Nov 9, 2020 at 3:00 pm
That was beautiful
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tcr!
· Nov 9, 2020 at 3:11 pm
thank you so much!
$m.wand.ajax_cli...2020-11-0900 min
tcr! diaries - podcastRainy day bug ride
content: Oct 28, 2020
Video (MP4): 20201018 - Rainy day bug ride
In their downtime some people like to watch sports. Some people like to sew. Some people like to forage for frogs while frolicking in the forest. I like to pretend Iâm a medieval composer while Maggie puts on her cinematographer cap and weâre driving around town in the sprinkling rain.
#diariespodcast #diariesvideo #maggie
jimi hindrance experience
· Oct 28, 2020 at 2:06 pm
Liked it. Holy Guacamole thatâs a sweet bug!
$m.wand.ajax_click=true;$m.wand.lightsw...2020-10-2800 min
tcr! diaries - podcastBreak On Through by The Doors
content: Dec 1, 2017 · podcast: Aug 14, 2020
Audio (MP3): 20171201 - Break On Through by The Doors
https://www.youtube.com/watch?v=rOpQjD-rX0g
Peeps, hereâs your the-gate-is-straight Friday jam.
Listening to The Doors when I was 9 and 10 opened up my musical world so much more than bands like the Beatles did. Donât get me wrong, I love yellow submarines as much as the next u-boat commander but I met the darkly cool poet persona in songs like The End and Waiting for the Sun. I became all too familiar with the torture of lo...2020-08-1400 min
tcr! diaries - podcastSmelling like coffee and Captain Morgan
content: Jul 6, 2017 · podcast: Jul 30, 2020
Audio (MP3): 20170706 - Smelling like coffee and Captain Morgan
One time I was driving to work on a hot summer morning. Just like today. Hung over pretty bad and nursing a pint of rum. I was in complete agony, had a fiery headache, and starting to sweat because my truck didn't have air conditioning. Taking shots now and then while auto-piloting the blue Ranger along the river. I needed just enough liquor to bring my headache down to a manageable level so I could make it through until lunch.
2020-07-3000 min
tcr! diaries - podcastNo reason for me to be in a hurry
content: Aug 9, 2017 · podcast: Jul 26, 2020
Audio (MP3): 20170809 - No reason to be in a hurry
Sometimes I got something going on, something Iâm burning too much daylight on, and I canât figure it out. The path isnât clear. The monkey chatter is as loud as it gets and I feel myself ratcheting up.
One time way back in high school I was struggling with a drawing. When I asked my art teacher for help she told me that Iâd overworked it. And she was right, plain as day, clear as mud. I...2020-07-2600 min
tcr! diaries - podcastVirtual Bunker Tour
content: May 17, 2020
Video (MP4): 20200517 - Virtual Bunker Tour
Please enjoy a view from the futon in the office bunker.
#diariesvideo #basement
jenkins_arts
· May 17, 2020 at 2:41 pm
Excellent!
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tcr!
· May 17, 2020 at 5:22 pm
Yes and no đ
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jimi hindrance experience
· May 17, 2020 at 8:08 pm
The Hunker Bunker
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Uncle Timmy
· May 17, 2020 at 10:06 pm
2020-05-1700 min
tcr! diaries - podcast100 percent decent
content: May 2, 2019 · podcast: Apr 11, 2020
Audio (MP3): 20190502 - 100 percent decent
You guys remember when Bill and Ted said, âbe excellent to each other.â
I loved that line and that movie but being excellent all the time is hard. Like Iâm driving and some fuckwad cuts me off, and then comes to a near complete stop when turning right. Excellence is the about the last thing in my fingertips.
Put them in the iron maiden đ€
You guys know about washing machines and when they agitate clothes. I can feel a...2020-04-1100 min
tcr! diaries - podcastDesperately Seeking Cup of Water
content: Sep 24, 2018 · podcast: Apr 5, 2020
Video (MP4): 20180924 - Desperately Seeking Cup of Water
Audio (MP3): 20180924 - Desperately Seeking Cup of Water
I would get one myself but Iâve just settled in for my late afternoon nap. I donât need a full glass, a full cup will do. I know youâve been there: partially parched and close to near death as your bones wither down to the marrow.
Plastic cups with the Millennium Falcon are preferred. Thor artwork will do. Toy Story cartoons are forbidden.
Pleas...2020-04-0500 min
tcr! diaries - podcastsometimes you want something so bad
content: Sep 5, 2019 · podcast: Mar 27, 2020
Audio (MP3): 20190905 - sometimes you want something so bad
Video (MP4): 20190905 - sometimes you want something so bad
Peeps, you know how sometimes you want something so bad. Think about it day after day, get angry and frustrated because nothing changes⊠I get it. Iâve had my fair share of being stuck in jobs, relationships, stuck in some kind of mud.
But trust me when I say that good things are being sorted out in the background. Too often it takes a long mother-clucking time...2020-03-2700 mintcr! diaries - podcastUnrelenting Happiness
content: Apr 15, 2012 · podcast: Mar 6, 2020
Audio (MP3): 20120415 - Unrelenting Happiness
Feelings need not always be put into words. They can just be felt, like tigers or butterflies, snake bites or feline purrs. After they're done (and even if they're not), open your heart to the love, to the glow of the Universe. It's there waiting and it's yours. It's your right, your entitlement and a perquisite to unrelenting happiness.
#lettherebehope #diariespodcast
tcr!
· Apr 15, 2012 at 11:01 am
Drinking from that cup embraces us with a power that withers all evil sp...2020-03-0600 min
tcr! diaries - podcastNo horse blankets
content: Apr 10, 2019 · podcast: Jan 18, 2020
Audio (MP3): 20190410 - No horse blankets
When I got to the place where I couldnât stand myself anymore, where I didnât want to be the person Iâd always been. And not do the same things Iâd always done, I can see now thatâs when I had reached the breaking point.
The pain of being me had broken my very soul. Fuck.
It wasnât the drinking, it wasnât ever the drugs. It was me. It wasnât the traffic or the ot...2020-01-1800 min
tcr! diaries - podcastA backlog of taxes
content: Nov 12, 2018 · podcast: Jan 12, 2020
Audio (MP3): 20181112 - A backlog of taxes
I spent the majority of my adult life either toiling around to get my head on straight or hiding in the shadows from the truth.
A backlog of taxes and overdue books.
Pull up a little bit farther at the red light because I donât want to look at the dude next to me. Itâs not that I didnât wanna go to college. Itâs just that my ship was listing and the captain was drunk...2020-01-1200 min
tcr! diaries - podcastInwardly summiting a spiritual Mt Everest
content: Dec 29, 2019 · podcast: Jan 11, 2020
Audio (MP3): 20191229 - Inwardly summiting a spiritual Mt Everest
Seeking equality, fairness, the greater good...that does something remarkable for me. It breaks my selfish bubble. It makes me a whole human being. It gives me freedom.
But wait, thereâs more. So much more. Seeking balance and harmony for all...brings me out of my despair. It brings light to my darkness. It brings healing to my pain. It lifts me up and out of feeling down and blue, up to the level of okay I w...2020-01-1100 min
tcr! diaries - podcastdiaries for 2018 - book now available
content: Apr 29, 2019
Audio (MP3): 20190429 - diaries for 2018 - book now available
After all my moaning my 2018 diaries book is now ready to be put in your shopping carts. If you have an unfulfilled diaries magazine subscription donât buy the book. Your paperback will be in the mail soon.
The ones available here on the site are autographed, too. Paperback and Kindle editions are available on Amazon, non-autographed of course.
You should buy my book. And then tell your friends about it. And share it on social media, as...2019-04-2900 min
tcr! diaries - podcastPillsbury's Candy Apple frosting
content: Oct 14, 2018 · podcast: Apr 18, 2019
Audio (MP3): 20181014 - Pillsbury's Candy Apple frosting
Sometimes Iâll got out on a culinary limb. A daring yet delectable escapade, laying out loads of cash for adventurous taste combinations that send the conservatives repulsed to the bakeries of safety.
For example, in this year of 2018, this month of October, I dropped Candy Apple frosting from Pillsbury into my basket, impromptu style while in the aisles of Blue Goose. A one-handed yet non-acrobatic feat that impressed shoppers clear yonder to the western deli department.
Bas...2019-04-1800 mintcr! diaries - podcastDo you ever wake up cranky for no good reason?
content: Sep 28, 2018 · podcast: Mar 14, 2019
Audio (MP3): 20180928 - Do you ever wake up cranky for no good reason?
And then when youâre walking down the stairs you say âfuck those guysâ but there are no guys there?
And then when youâre standing in the kitchen getting your lunch ready you see a teeny purple flower on the floor and say âget the fuck out of hereâ and kick it under the stove?
And then Alexa plays Kiss Me Deadly and then you think to yourself âWhy does Ozzy get to hold heaven...2019-03-1400 min
Test & Code68: test && commit || revert (TCR) - Thomas DeniffelWith conventional TDD, you write a failing test, get it to pass, then refactor.
Then run the tests again to make sure your refactoring didn't break anything.
But what if it did break something?
Kent Beck has been recommending to commit your code to revision control after every green test run.
Oddmund StrĂžmme suggested a symmetrical idea to go ahead and revert the code when a test fails.
Kent writes that he hated the idea, but had to try it.
Then wrote about it last September.
And now we have TCR, "(t...2019-03-1338 min
@Autoweird.fmFolge 57: TCR - test/commit/revert (aka. hacks noch einmal Sam!)
Da war doch was in der Timeline? Mal wieder eine neue AbkĂŒrzung! Von der alle reden! ALLE! Jetzt mĂŒssen wir doch auch mal schauen, was es damit auf sich hat.
Die Rede ist natĂŒrlich(tm) von TCR â oder test && commit || revert, einer verschĂ€rften Abwandlung von TDD. Es geht darum, Code automatisch zu committen falls die Tests grĂŒn sind und wegzuwerfen, falls nicht. Abgefahren!
Ja, so ganz passt das nicht mit der TDD-Abwandlung, TCR hat da noch andere Zielsetzungen (wir greifen mal wieder vor). âAber Leute die TDD mögen, mögen auchâ âŠ...2019-02-241h 13
tcr! diaries - podcasttcr! diaries podcast survey
content: Aug 24, 2018 · podcast: Jan 30, 2019
Audio (MP3): 20180824 - Podcast Survey
Iâm interrupting the regularly scheduled episodes to announce a listener survey created by yours truly. Itâs informal and there wonât be a test later. And I love your feedback!
Itâs also quick and should take you less than 30 seconds.
Go now: tcrbang.com/form/podcast_survey/
On with the show.
#tcr #webdev #diariespodcast
Add a comment!
Got 30 seconds? Take the super duper, quick and easy podcast survey! Please. đ...2019-01-3000 mintcr! diaries - podcastShare the road with bikes?
content: Jun 14, 2018 · podcast: Dec 7, 2018
Audio (MP3): 20180614 - Share the road with bikes?
How about they go the speed limit? Or obey the traffic signals? Or decide if theyâre going to be on the street or the sidewalk?
I ride my bike as much as anybody. Okay, thatâs not true. I have a bike in my garage and Iâve only ridden a few times this year.
But Iâve seen the guy at Sammyâs Bikes race around town, blow through stop signs, make wild ass turns without warning, we...2018-12-0700 mintcr! diaries - podcastA frantic game of animal tag
content: Jun 11, 2018 · podcast: Dec 2, 2018
Audio (MP3): 20180611 - A frantic game of animal tag
On this morning, the 11th of June I was greeted with a squeaky chipmunk in the basement just as I sat down with my first cup of coffee. It filled my heart with joy as the two H-Ks (hunter killers) and a lone chipmunk played a frantic game of animal tag.
A frenzied game of hide and seek if you will. Where if you lose needly claws hooked to hair trigger tendons pulled by honed muscles will rip into y...2018-12-0200 min
CAR-TTCR engineeringWe have high qualified groups and advanced technologies to perform TCR engineering services covering every unit of manufacturing and delivery pipeline. From a tumor-reactive T cell or active anti-tumor T-cell antigens, the appropriate target sequence is introduced to modify T cells to target a broad range of tumors with improved specificity. With engineering TCR construction and a series of assay, such as transgene expression, TCR/CD3 stability, lymphocyte antigen reactivity and cytotoxicity, animal experiments, etc., we provide cGMP-compliant TCR products for preclinical and clinical trials. Learn more about TCR T cells. https://www.creative-biolabs.com/car-t/cellrapeutics-tcr-technology.htm2018-11-2900 min
tcr! diaries - podcastSaturated, colorful clematis
content: May 18, 2018 · podcast: Nov 8, 2018
Audio (MP3): 20180518 - Saturated, colorful clematis
And on this 18th day of May nature said lettuce have more flowers, specifically the saturated, colorful clematis. And the peeps of the world drew in a beautiful breath and embraced the brilliance.
And then on a related note the man said, âIf life is fleeting then that is irrelevant. In this minute let lifeâs focal point be the vibrancy.â
#photos #flowers #diariespodcast
jimi hindrance experience
· May 18, 2018 at 9:45 am
Holy shit, who is the a...2018-11-0800 min
Il podcast di Motorsport Republic+Intervista Marcello Lotti: WTCR, E-TCR. La crescita inarrestabile del Turismo da corsaMarcello Lotti era il manager esecutivo del WTCC (il Campionato Mondiale Turismo). Circa cinque anni fa per una serie di manovre al vertice organizzativo della Categoria del Turismo lui esce di scena e si mette subito al lavoro su una idea di vettura nuova, su un nuovo regolamento. Obiettivo: rilanciare una specialitĂ in crisi per costi e, quindi, partecipazioni. Tre anni fa lanciĂČ il TCR e oggi, alla vigilia della quarta stagione, il TCR diventa lo standard mondiale della Categoria Turismo. Un successo inarrestabile che conta oltre 50 Paesi dove si corrono i Campionati Nazionali secondo la regola TCR e un Ca...2018-03-3034 min
Il podcast di Motorsport Republic+Intervista Marcello Lotti: WTCR, E-TCR. La crescita inarrestabile del Turismo da corsaMarcello Lotti era il manager esecutivo del WTCC (il Campionato Mondiale Turismo). Circa cinque anni fa per una serie di manovre al vertice organizzativo della Categoria del Turismo lui esce di scena e si mette subito al lavoro su una idea di vettura nuova, su un nuovo regolamento. Obiettivo: rilanciare una specialitĂ in crisi per costi e, quindi, partecipazioni. Tre anni fa lanciĂČ il TCR e oggi, alla vigilia della quarta stagione, il TCR diventa lo standard mondiale della Categoria Turismo. Un successo inarrestabile che conta oltre 50 Paesi dove si corrono i Campionati Nazionali secondo la regola TCR e un Ca...2018-03-3035 minIl podcast di Motorsport Republic+Intervista Marcello Lotti: WTCR, E-TCR. La crescita inarrestabile del Turismo da corsaMarcello Lotti era il manager esecutivo del WTCC (il Campionato Mondiale Turismo). Circa cinque anni fa per una serie di manovre al vertice organizzativo della Categoria del Turismo lui esce di scena e si mette subito al lavoro su una idea di vettura nuova, su un nuovo regolamento. Obiettivo: rilanciare una specialitĂ in crisi per costi e, quindi, partecipazioni. Tre anni fa lanciĂČ il TCR e oggi, alla vigilia della quarta stagione, il TCR diventa lo standard mondiale della Categoria Turismo. Un successo inarrestabile che conta oltre 50 Paesi dove si corrono i Campionati Nazionali secondo la regola TCR e un Ca...2018-03-3035 mintcr! diaries - podcastA get-together this coming Saturday
content: Feb 17, 2018 · podcast: Mar 27, 2018
Audio (MP3): 20180217 - A get-together this coming Saturday
Iâm *thinking* about having a get-together this coming Saturday, February 24th. If youâre reading this youâre invited. It would be a social mixer of sorts with snacks and drinks. No, Iâm not making you all dinner. Tater-tots could possibly be available.
It would be kid friendly, too, since Maggie would also be hosting. Also, since you all know me you know that I donât drink anymore. Itâs not that I didnât like drinking, it was more tha...2018-03-2700 mintcr! diaries - podcastThrowing it on the floor
content: Feb 11, 2018 · podcast: Mar 16, 2018
Audio (MP3): 20180211 - Throwing it on the floor
I hate when I go to throw something away and then just end up throwing it on the floor. I mean, what the hell is this? Itâs not like Iâm threading the space shuttle needle in the vacuum of outer space.
And then I forgot to put a dryer sheet in with my clothes so when I pulled them from the dryer, they all looked as if they were made from the hide of the great northern yeti.
2018-03-1600 mintcr! diaries - podcastA cranberry stuck
content: Feb 9, 2018 · podcast: Mar 9, 2018
Audio (MP3): 20180209 - A cranberry stuck
The scene is my work desk. I'm eating cashew, almond, and cranberry trail mix. One of the cranberries jumped from the cup. I saw it happen but didn't hear the landing. After a mildly-extensive berry-hunt the fruit-trail gone-went cold. I cannot find the little asshole. I fear I may be walking around with a cranberry stuck on my ass for the rest of the day.
I'm gonna power down my computer. Pack up my snacks, shave my head, braid my beard. Leave t...2018-03-0900 min
tcr! diaries - podcastHere's what happens when you unfriend someone
content: Feb 2, 2018 · podcast: Mar 7, 2018
Audio (MP3): 20180202 - Here's what happens when you unfriend someone
This showed up on my timeline just a little bit ago.
So Facebook ânoticedâ I unfriended somebody. I highly doubt if they just ânoticedâ anything. They KNOW our every move people. They track and follow said movements even when weâre not on their website or using their apps.
These social media overlords go so far as having shadow accounts of people that donât have real, actual Facebook accounts. Oh yeah, itâs true. Your dead...2018-03-0700 mintcr! diaries - podcastUnder Maggie's pillow
content: Jan 9, 2018 · podcast: Feb 16, 2018
Audio (MP3): 20180109 - Under Maggie's pillow
And then there was that one time maybe six or seven years ago when I ate a Snickers fun-size and hid the wrapper under Maggieâs pillow.
And then at bedtime when we found it and she was horrified of being convicted of a crime she didnât commit, after she had time to process and I confessed, she thought it was funny.
And she still does. Because I asked her about it earlier tonight before dinner.
âAnd you tri...2018-02-1600 mintcr! diaries - podcastMaggie and I talk bacon
content: Feb 2, 2018
Audio (MP3): 20180202 - Maggie and I talk bacon
I picked Maggie up from her mom's and on a whim we did a quick, off the cuff podcast in my truck on the way back home.
There's some background noise but that's what happens when you're recording while driving 45 mph. And yes, she was holding the phone and not me. Safety first kids.
Also, neither of us had prepared for this. Spontaneity in all its glory.
#maggie #diariespodcast
prokop
· Feb 2, 2018 at 5:49 pm
2018-02-0200 min
tcr! diaries - podcastWe don't want to spoil his suprise
content: Sep 21, 2017 · podcast: Nov 22, 2017
Audio (MP3): 20170921 - We don't want to spoil his suprise
In follow up to August 16th's Provocative yet professional
#email #hirasfashion #diariespodcast
keamoose
· Sep 21, 2017 at 7:31 pm
They did leave the door open for that with âand moreâ.
Have you seen this? http://thebloggess.com/2017/01/04/im-gonna-be-a-vampire-maybe/
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tcr!
· Sep 22, 2017 at 6:58 am
I hadnât seen that but late last night I was all over it like a one-tooth...2017-11-2200 mintcr! diaries - podcastAmazing blueberry jelly
content: Oct 19, 2017 · podcast: Nov 1, 2017
Audio (MP3): 20171019 - Amazing blueberry jelly
I hate it when I'm walking down the work hallway and I hear another office door open. Can't I just walk down the hall alone, with peace and quiet?
Now matter how much I try to avoid people, some random body shows up and says, "hello." And then I have to quickly scan the mental rolodex for non-offensive chit-chat. Engage in dialogue that obviously won't last more than 15 seconds.
It's not that I don't like the other office building inhabitants b...2017-11-0100 mintcr! diaries - podcastMore knob twists
content: Oct 27, 2017 · podcast: Nov 1, 2017
Audio (MP3): 20171027 - More knob twists
Iâm in the private, single person work restroom. Somebody tries the door knob. It refuses because Iâm not an animal and therefore lock the door.
Again, with the twisting. I scowl at the door. More knob twists. This time as if brute force will unlock the door. Iâm annoyed now.
Three seconds pass. The knob twists yet again. I call out forcefully, angrily... âdude, Iâm taking a shit.â
I donât like talking to people in publi...2017-11-0100 min
tcr! diaries - podcastWhy are there so many pubes
content: Sep 18, 2017 · podcast: Oct 17, 2017
Audio (MP3): 20170918 - Why are there so many pubes
Why are there so many pubes in the damn urinals? What the hell are people doing in there? đ
#socialproblems #diariespodcast #publicrestroom
tcr!
· Sep 18, 2017 at 4:04 pm
Mona mentioned on FB, âfolks not getting enough vitamins.â
So I made a signâŠ
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Add a comment!
Got 30 seconds? Take the super duper, quick and easy podcast survey! Please. đ
Love the show? Make a donatio...2017-10-1700 min
tcr! diaries - podcastSunrise for Sep 27, 2017
content: Sep 27, 2017 · podcast: Sep 30, 2017
Audio (MP3): 20170927 - Sunrise for Sep 27 2017
Peeps, what was happening for me a few moments ago was a wonderful pinky orange sunrise. Itâs Wednesday so weâre half-way through the week. Who can argue with hump day? NOBODY. Thatâs who.
Also, I could really use Desperately Seeking Susan on DVD. Ya, itâs from the 80s but still holding 88% on the Tomatoes. Bonus: if you have the soundtrack on vinyl youâll be invited to the masquerade ball next month. Donât just say you got it, y...2017-09-3000 mintcr! diaries - podcastWhat's Happening in Geneva, Facebook group
content: Sep 24, 2017 · podcast: Sep 27, 2017
Audio (MP3): 20170924 - By the name a Thelma Louise
I may need to leave the What's Happening in Geneva Facebook group. I keep wanting to help with my web expert advice, wit, and charm. Below are two examples that I could barely resist (but did).
Hi there, I Need recommendation for washing machine fix.... thank
You're gonna go all the way down about half a block and you'll see a Torino with no wheels on it. Now, inside that Torino is my cousin, Jackie. N...2017-09-2800 mintcr! diaries - podcastJul 2nd, 2017 at 2:42:05 am
content: Jul 2, 2017 · podcast: Sep 17, 2017
Audio (MP3): 20170702 - Starting tomorrow
Starting tomorrow I will randomly and routinely wake the cats up during the day because, no matter how many times we talk about this, they continually wake me up in the middle of the night with their bullshit. And yes, when I do it will be in such a way as to scare them shitless.
#cats #napsarespiritual #diariespodcast
tcr!
· Jul 2, 2017 at 4:38 pm
I really want to scare her shitless but sheâs on my leg and I worry ther...2017-09-1700 mintcr! diaries - podcasttcr! diaries podcast now available
content: Aug 21, 2017 · podcast: Sep 17, 2017
Audio (MP3): 20170821 - tcr diaries podcast now available
So this is a thing now. Keep your expectations low. I mean like really low. I don't know if it'll be anything more than just an audio version of a written piece. We'll see how it goes. Maybe I'll ad-lib now and then. Maybe I'll play the piano. At this point I'm just trying to get used to the sound of my own damn voice. đ
You can listen on iTunes
And you can listen on SoundCloud
And you can list...2017-09-1700 min
tcr!20170816 - Morning drinks mute the fires of hell.mp320170816 - Morning drinks mute the fires of hell.mp3 by tcr!2017-08-1602 min
tcr!20170813 - All Out of Love by Air Supply20170813 - All Out of Love by Air Supply by tcr!2017-08-1301 min
tcr!20170810 - Seeking colorful Christian martyr to repel repeated Jehovah's Witness20170810 - Seeking colorful Christian martyr to repel repeated Jehovah's Witness by tcr!2017-08-1003 min
tcr!20170804 - Slip Slide Melting by For Love Not Lisa20170804 - Slip Slide Melting by For Love Not Lisa by tcr!2017-08-0402 min
tcr!i'm not a hybridi'm not a hybrid by tcr!2013-09-1005 min
FakultĂ€t fĂŒr Biologie - Digitale Hochschulschriften der LMU - Teil 04/06Recognition of renal cell carcinoma by CD8+ and CD4+ TCR-engineered T lymphocytesImmunotherapy using T cells is a new approach that is being explored for the treatment of metastatic melanoma. For renal cell carcinoma (RCC), adoptive T cell therapy (ATT) is currently hampered by the lack of T cells expressing suitable T cell receptors (TCR). A tumor-infiltrating T cell population (TIL) was identified in our group (TIL-53) that showed a pattern of tumor recognition consistent with the requirements of a TCR applicable for immunotherapy. With the advent of genetic TCR engineering it was possible to further define the TIL specificity which was previously precluded by the failure to cultivate TIL-53. To achieve...2011-02-2100 min
Journal Club Imunoterapia TumoralEdição#8: Flexibilidade do CDR3 do TCR comprovada por cristalografia. ImplicaçÔes no reconhecimento antigénico pelos linfócitos T.Olå malta!
Neste oitava edição do Podcast Imunoterapia
Tumoral apresento-vos o artigo de Gakamsky
et al, publicado recentemente no jornal PNAS vol 104: 16639
de 2007.
Este artigo vem pela primeira vez corroborar com dados de
biofĂsica os dados apresentadas por vĂĄrios
trabalhos baseados em cristalografia do complexo TCR/peptideo-MHC, e
onde Ă© sugerida
de o domĂnio do CDR3 Ă© capaz de uma certa
mobilidade e capacidade de adaptar-se ("fiting") Ă
superfĂcie tri-dimensional do complexo
peptĂdeo-MHC.
Para relembrar: o TCR é o receptor da célula T,
que reconhece peptĂdeos (oligopeptideos) apresentados pela
molecula Major de Histocompatibilidade (MHC). As células T
sĂŁo de...2007-12-0818 min