Shows
VJOncology PodcastSarcoma awareness month: advances in precision medicineIn this weeks podcast from VJOncology, five leading experts share updates and insights on the evolving landscape of precision medicine in sarcoma.
Robin Jones discusses the complexities of implementing precision medicine and presents results from a Phase III trial of catequentinib in advanced leiomyosarcoma. Javier Martín-Broto explores recent advances in immunotherapy and shares findings from Cohort 7A of the ImmunoSarc2 trial, evaluating epirubicin and ifosfamide plus nivolumab in undifferentiated pleomorphic sarcoma. Nadia Hindi highlights Cohort 2, which assessed sunitinib and nivolumab in extraskeletal myxoid chondrosarcoma. Ramya Ramaswami addresses unmet needs in Kaposi sarcoma and presents data from a...2025-07-2521 minVJOncology PodcastCAR-T and cellular therapy updates in brain tumorsIn this week’s VJOncology podcast, we have the pleasure to bring you key updates in CAR-T and cellular therapies in brain tumors. Gain expert insights on landmark trials, treatment advances, and shifting screening practices from some of the foremost voices in the field. Topics of discussion include a Phase I trial of intracranial B7H3-directed CAR-T cell therapy in patients with recurrent glioblastoma, effective strategies in anti-glioblastoma CAR-T cells, and dendritic cell therapy in recurrent glioblastoma.
The post CAR-T and cellular therapy updates in brain tumors appeared first on VJOncology.
2025-07-1809 minVJOncology PodcastBreakthrough advances from ESMO GI 2025This week’s VJOncology podcast episode highlights four breakthrough studies from ESMO GI 2025 in Barcelona, Spain, featuring expert insights on gastrointestinal cancer advances. Coverage includes the EXPEL PANC study combining BXCL701 with pembrolizumab for pancreatic cancer, SIERRA study safety data on the STRIDE regimen for hepatocellular carcinoma, TALENTACE trial results combining TACE with atezolizumab plus bevacizumab, and updated MATTERHORN study data on perioperative immunotherapy for gastric cancer. Leading oncologists share perspectives on these game-changing developments reshaping GI cancer treatment live from Barcelona, Spain.
The post Breakthrough advances from ESMO GI 2025 appeared first on VJOncology.
2025-07-1112 minVJOncology PodcastGynecological cancer updates at ASCO 2025In this weeks VJOncology podcast, we have the pleasure to bring you key updates in gynecological cancer from ASCO 2025, which we attended live in Chicago, IL. Join leading experts as they comment on key trials and provide their insights on the ever-evolving treatment landscape and screening patterns.
Dr Jyoti Mayadev gives an overview of highly anticipated trials at the conference including the CALLA, OUTBACK and KEYNOTE-A18 trials, and Dr Shannon Westin discusses findings from the ctDNA findings from the DUO-E trial in endometrial cancer. Dr Kamran Ahmed comments on the efficacy of SBRT followed by atezolizumab in...2025-06-2010 minVJOncology PodcastBreakthrough advances from ASCO 2025In this ASCO 2025 edition of VJOncology podcasts, we spotlight five game-changing studies set to reshape cancer care across multiple tumor types.
Join our host and a panel of leading oncology experts as they unpack the most impactful data from this year’s American Society of Clinical Oncology Annual Meeting. Discover pivotal insights from the MATTERHORN trial in gastric cancer, explore KRAS G12C-targeted combinations in NSCLC, and delve into resistance-prevention strategies in HR+/HER2– breast cancer with findings from the SERENA-6 trial. We also explore the potential of mRNA-based bispecific antibodies for solid tumors and analyze expanded resu...2025-06-1317 minVJOncology PodcastVJOncoAlert Journal ClubIn this week’s podcast, we take you through the latest episodes of the VJOncoAlert Journal Club—a collaborative series from VJOncology and OncoAlert that brings together leading oncology experts to discuss the most impactful and practice-changing research in the field.
We are joined by Misty Shields, MD, PhD, from the Indiana University Simon Comprehensive Cancer Center in Indianapolis, IN, who discusses the latest updates in small cell lung cancer. Thomas Powles, MBBS, MRCP, MD, of Barts Cancer Institute in London, UK, and Brian Rini, MD, FASCO, of Vanderbilt-Ingram Cancer Center in Nashville, TN, comment on the heal...2025-04-2521 min
VJOncology PodcastVJOncoAlert Journal ClubIn this week’s podcast, we take you through the latest episodes of the VJOncoAlert Journal Club—a collaborative series from VJOncology and OncoAlert that brings together leading oncology experts to discuss the most impactful and practice-changing research in the field.
We are joined by Misty Shields, MD, PhD, from the Indiana University Simon Comprehensive Cancer Center in Indianapolis, IN, who discusses the latest updates in small cell lung cancer. Thomas Powles, MBBS, MRCP, MD, of Barts Cancer Institute in London, UK, and Brian Rini, MD, FASCO, of Vanderbilt-Ingram Cancer Center in Nashville, TN, comment on the heal...2025-04-2521 minVJOncology PodcastAdjuvant Therapy for Hepatocellular CarcinomaWelcome to this week’s podcast by VJOncology, where we delve into the latest developments in adjuvant therapy for hepatocellular carcinoma. Join five leading experts as they discuss cutting-edge research and its impact on clinical practices.
Stephen Chan, MBBS, MRCP, The Chinese University of Hong Kong, Hong Kong, China, Laura Williams Goff, MD, MSCI, MMHC, Vanderbilt-Ingram Cancer Center, Nashville, TN, Lorenza Rimassa, MD, IRCCS Humanitas Research Hospital, Milan, Italy, Pierce Chow, MBBS, MMed (Surg), FRCS (Edin), FAMS (Gen Surg), PhD, National Cancer Centre Singapore & Duke-NUS Medical School Singapore, Singapore, and Ghassan Abou-Alfa, MD, MBA, Memorial Sloan Kettering Canc...2025-04-0410 minVJOncology PodcastProstate cancer awareness month: advances in liquid biopsiesIn this week’s VJOncology podcast, we are focusing again on Prostate Cancer Awareness Month, where we have collaborated with experts on liquid biopsies for tracking and predicting treatment outcomes in metastatic castration-resistant prostate cancer.
Join Chinmay Jani from the Sylvester Comprehensive Cancer Centre, Xin Gao from Massachusetts General Hospital Cancer Center, Christos Kyriakopoulos from the University of Wisconsin, Andrew Armstrong from the Duke Cancer Institute, and Susan Halabi from Duke University Medical Center, as they present various trial updates and their exclusive insights from this burgeoning field.
The post Prostate cancer awareness month: advances in...2025-03-2810 minVJOncology PodcastBTOG 2025 HighlightsIn this weeks VJOncology podcast, we explore key update from BTOG 2025 in thoracic oncology.
Prof. Sanjay Popat discusses the evolving role of ADCs in lung cancer treatment, focusing on efficacy, toxicity management, and biomarker integration. Prof. Samreen Ahmed examines ADC resistance mechanisms, drawing insights from breast cancer therapy to refine drug development strategies. Prof. Robert Rintoul reviews a new UK Lung Cancer Coalition report on genomic testing challenges and strategic solutions for faster diagnostics. Dr Adam Januszewski highlights the complexities of implementing genomics in the UK and the need for a streamlined approach. Prof. Neal Nivani concludes...2025-03-2121 minVJOncology PodcastLiquid biopsy in breast cancerIn this weeks VJOncology podcast, three oncology experts delve into the transformative potential of liquid biopsy in breast cancer treatment.
First, Michail Ignatiadis (Jules Bordet Institute, Brussels, Belgium) discusses the clinical applications and challenges of utilizing liquid biopsy in metastatic breast cancer, focusing on the Phase III TREAT ctDNA trial (NCT05512364) and its implications for ER-positive, HER2-negative cases. Next, Marina Sharifi (University of Wisconsin Carbone Cancer Center, Madison, WI) introduces an innovative fragmentomic analysis of circulating tumor DNA (ct-DNA) to discern ER status in metastatic breast cancer, potentially minimizing the need for invasive tissue biopsies. Finally...2025-03-1410 minVJOncology PodcastCellular therapies in solid tumorsWelcome to this week’s podcast by VJOncology, where we delve into the emerging trends and challenges in the field of cellular therapies for oncology. Our expert panel includes Leonardo Ferreira (The Medical University of South Carolina, Charleston, SC), who discusses the groundbreaking potential and current obstacles of CAR T cells in treating solid tumors, emphasizing the innovative role of chimeric antigen receptor regulatory T cells.
We also hear from Sebastian Klobuch (Netherlands Cancer Institute, Amsterdam, The Netherlands) on the advancements in TIL and TCR-modified therapies. He explores potential ways to mitigate treatment toxicities and expand the ap...2025-02-1415 minVJOncology PodcastTherapeutic options for PD1 refractory skin cancerIn this podcast, we explore the latest advancements in the treatment of PD-1 refractory melanoma. This week, we are joined by Allison Betof Warner (Stanford Cancer Center, Stanford, CA) and Omid Hamid (The Angeles Clinic and Research Institute, Los Angeles, CA) and Inderjit Mehmi (The Angeles Clinic and Research Institute, Los Angeles, CA).
We will hear about the clinical definitions and significance of PD-1 resistance, including insights from SITC on primary and secondary resistance. The discussion will also highlight the implications for clinical trial design and strategies to overcome resistance in melanoma therapy. Updates on emerging treatment opt...2025-01-2432 minVJOncology PodcastNovel immune checkpoint targets beyond PD-1 and CTLA-4 in solid tumorsThis week’s podcast from VJOncology brings you the latest updates on novel checkpoint inhibitors that target LAG-3, TIGIT, and TIM3 in solid tumors. Our panel of experts share the latest findings from their clinical trials that tested the efficacy of different immune checkpoint inhibitors in neoplastic tumors.
Myriam Chalabi from the Netherlands Cancer Institute shares results from the NICHE-2 and NICHE-3 trials on MMR-deficient colon cancer, and Girish Kulkarni from the University of Toronto discusses the cohort C section of the KEYNOTE-057 trial, followed by the potential role of TIGIT/LAG-3 inhibition for urothelial carcinoma treatment. Gh...2025-01-1013 minVJOncology PodcastAntibody drug conjugates in gastrointestinal cancersThis week’s podcast from VJOncology brings you key updates in antibody drug conjugates (ADCs) for gastrointestinal cancer. Our expert panel discusses the potential of ADCs targeting HER2, CMET, and CEACAM5 in gastric and colorectal cancers.
Hear from experts Kohei Shitara (National Cancer Center Hospital East), Yelena Janjigian (Memorial Sloan Kettering Cancer Center), John Strickler (Duke Cancer Institute), and Scott Kopetz (MD Anderson Cancer Center) as they provide an overview of the latest in ADCs for gastrointestinal cancers. Highlights include novel treatment strategies in HER2-expressing gastric cancer, findings from the DESTINY-Gastric03 and ABBV-400 trials, and the ro...2024-11-2912 minVJOncology PodcastNovel therapeutics in PD-1 refractory melanomaThis week’s podcast from VJOncology explores key advancements in the treatment of PD-1 refractory melanoma. Hear from leading experts, Alison Betoff Warner (Stanford University, Stanford, CA), Andrew Furness (Royal Marsden Hospital, London, UK), Anna Di Giacomo (University Hospital of Siena, Siena, Italy), María Vieito (Vall d’Hebron Institute of Oncology, Barcelona, Spain), and Yana Najjar (UPMC Hillman Cancer Center, Pittsburgh, PA), as they share insights into cutting-edge therapies and trials.
Highlights include the FDA approval of TIL therapy in metastatic melanoma, early findings on off-the-shelf T-cell therapy, and results from the NIBIT-ML1 trial (NCT04250246) investigating a tri...2024-11-1526 minVJOncology PodcastGI updates from ESMO 2024This week’s podcast from VJOncology brings you key updates in gastrointestinal cancer from the European Society of Medical Oncology (ESMO) 2024 annual meeting, which took place in Barcelona, Spain.
Hear from experts, Jessie Elliot (Trinity St. James’s Cancer Institute), Myriam Chalabi (Netherlands Cancer Institute), and Changhoon Yoo (Asan Medical Center) as they discuss the latest in biliary tract and colon cancers, as well as gastric and gastroesophageal junction adenocarcinoma. Highlights include findings from the TOPGEAR trial, extended follow-up results from the NICHE-2 and the NICHE-3 trials, as well as findings from the NIFTY and NALIRICC studies.
2024-11-0411 minVJOncology PodcastESSO 43 highlightsIn this podcast, we bring you exclusive insights from the 43rd Congress of the European Society of Surgical Oncology (ESSO 43), held in Antwerp, Belgium. We will be joined by Isabel Rubio, MD, PhD (Vall d’Hebron University Hospital, Barcelona, Spain), who discusses the dual focus of modern cancer surgery and the transformative impact of robotic surgery; Sylvie Bonvalot, MD, PhD, HDR (Institut Curie, Paris, France), recipient of the ESSO Lifetime Achievement Award 2024, who reflects on her extensive experience with desmoid tumors and sarcoma surgery; and Mitsuru Sasako, MD, PhD (Yodogawa Christian Hospital, Osaka, Japan), recipient of the ESSO Gold Me...2024-10-1115 minVJOncology PodcastHighlights from ESMO 2024In this week’s podcast, we bring you updates from the ESMO 2024 Congress in Barcelona, Spain, featuring expert discussions on cutting-edge oncology research. We are joined by Peter Schmid, FRCP, MD, PhD, Barts Cancer Institute, London, UK; Minke Lukas, MD, Netherlands Cancer Institute, Amsterdam, Netherlands; Guru Sonpavde, MD, AdventHealth Cancer Institute, Orlando, FL; Sanjay Popat, MBBS, FRCP, PhD, The Royal Marsden Hospital, London, UK; Domenica Lorusso, MD, PhD, Fondazione IRCCS National Cancer Institute of Milan, Italy; and Dominik Modest, MD, Charité – Universitätsmedizin Berlin, Germany.
We’ll hear about final overall survival results from the Phase III KEYNOTE...2024-09-2020 minVJOncology PodcastHighlights from ESMO 2024In this week’s podcast, we bring you updates from the ESMO 2024 Congress in Barcelona, featuring expert discussions on cutting-edge oncology research. We are joined by Peter Schmid, FRCP, MD, PhD, Barts Cancer Institute, London, UK; Minke Lukas, MD, Netherlands Cancer Institute, Amsterdam; Guru Sonpavde, MD, AdventHealth Cancer Institute, Orlando, FL; Sanjay Popat, MBBS, FRCP, PhD, The Royal Marsden Hospital, London; Domenica Lorusso, MD, PhD, Fondazione IRCCS National Cancer Institute of Milan, Italy; and Dominik Modest, MD, Charité – Universitätsmedizin Berlin, Germany.
We’ll hear about final overall survival results from the Phase II KEYNOTE-522 trial (NCT03036488) of pembr...2024-09-2020 minVJOncology PodcastLatest updates in managing brain metastasesIn this podcast, we bring you the latest insights into managing brain metastases, with expert commentary from Minesh Mehta, MD, Miami Cancer Institute, Miami, FL; Sunandana Chandra, MD, MS, Northwestern University, Chicago, IL; Gaia Griguolo, MD, University of Padova, Padova, Italy; Orit Kaidar-Person, MD, Sheba Medical Center, Ramat Gan, Israel; and Janice Wing-Hang Tsang, MBBS, MRCP, FRCP, University of Hong Kong, Hong Kong, China,.
We will cover key findings from the Phase III METIS trial (NCT02831959), which explored Tumor Treating Fields (TTFields) therapy in patients with non-small cell lung cancer and brain metastases. Other topics include the...2024-09-1113 minVJOncology PodcastLatest updates in managing brain metastasesIn this podcast, we bring you the latest insights into managing brain metastases, with expert commentary from Manesh Mehta, MD, Miami Cancer Institute, Miami, FL; Sunandana Chandra, MD, MS, Northwestern University, Chicago, IL; Gaia Griguolo, MD, University of Padova, Padova, Italy; Orit Kaidar-Person, MD, Sheba Medical Center, Ramat Gan, Israel; and Janice Wing-Hang Tsang, MBBS, MRCP, FRCP, University of Hong Kong, Hong Kong, China,.
We will cover key findings from the Phase III METIS trial (NCT02831959), which explored Tumor Treating Fields (TTFields) therapy in patients with non-small cell lung cancer and brain metastases. Other topics include the...2024-09-1113 minVJOncology PodcastUpdates in immunotherapy for GU cancerIn this podcast, we highlight some of the latest updates in the use of immunotherapy to treat genitourinary cancer. This week we will be joined by Camillo Porta, MD, University of Bari Aldo Moro, Bari, Italy, Joaquim Bellmunt, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, Arlene Siefker-Radtke, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, and Maria Bourlon, MD, MS, El Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
We will cover findings from key trials, including CHECKMATE 901 on nivolumab with gemcitabine and cisplatin for metastatic urothelial carci...2024-08-2309 minVJOncology PodcastUpdates in immunotherapy for GU cancerIn this podcast, we highlight some of the latest updates in the use of immunotherapy to treat genitourinary cancer. This week we will be joined by Camillo Porta, MD, University of Bari Aldo Moro, Bari, Italy, Joaquim Bellmunt, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, Arlene Siefker-Radtke, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, and Maria Bourlon, MD, MS, El Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
We will discuss key findings from several pivotal trials, including the CHECKMATE 901 trial (NCT03036098), which evaluates nivolumab in combi...2024-08-2309 minVJOncology PodcastiwCAR-T sessions: clinical advances in lung cancerWelcome to another episode of VJOncology! In this episode, we dive into cutting-edge CAR-T cell therapies for the management of lung cancers, discussed at the sixth International Workshop on CAR-T in Miami, Florida.
Join Julian Molina from the Mayo Clinic, Ben Creelan from Moffitt Cancer Center, and Adam Schoenfeld from Memorial Sloan Kettering Cancer Center as they explore innovative CAR-T strategies and their applications in thoracic oncology. They address the challenges of integrating cell therapies in clinical practice, the potential for tumor cell banking, and the implications of tumor microenvironment modulation.
Discover insights into the...2024-07-1214 minVJOncology PodcastiwCAR-T sessions: CAR-T clinical advances in lung cancerWelcome to another episode of VJOncology! In this episode, we dive into cutting-edge CAR-T cell therapies for the management of lung cancers, discussed at the sixth International Workshop on CAR-T in Miami, Florida.
Join Julian Molina from the Mayo Clinic, Ben Creelan from Moffitt Cancer Center, and Adam Schoenfeld from Memorial Sloan Kettering Cancer Center as they explore innovative CAR-T strategies and their applications in thoracic oncology. They address the challenges of integrating cell therapies in clinical practice, the potential for tumor cell banking, and the implications of tumor microenvironment modulation.
Discover insights into the...2024-07-1214 minVJOncology PodcastiwCAR-T sessions: Clinical Advances in Head and Neck Cancer and Brain TumorsWelcome to another episode of VJ Oncology! In this episode, we delve into pioneering CAR-T strategies for head and neck cancers and brain tumors, as discussed at the recent iwCAR-T workshop in Miami, Florida.
Join Kedar Khartani from Moffitt Cancer Center and Susanna Baumeister from Dana-Farber Cancer Institute as they explore groundbreaking CAR-T approaches and clinical trials targeting glioblastoma and neuroblastoma. They address the challenges and future prospects of commercializing these therapies, particularly for rare and pediatric cancers.
Discover the exciting developments in ALK-targeting CAR-T cells for neuroblastoma and new antigen-selected TIL therapies for head...2024-06-0707 minVJOncology PodcastiwCAR-T sessions: Clinical Advances in Head and Neck Cancer and Brain TumorsWelcome to another episode of VJ Oncology! In this episode, we delve into pioneering CAR-T strategies for head and neck cancers and brain tumors, as discussed at the recent iwCAR-T workshop in Miami, Florida.
Join Kedar Khartani from Moffitt Cancer Center and Susanna Baumeister from Dana-Farber Cancer Institute as they explore groundbreaking CAR-T approaches and clinical trials targeting glioblastoma and neuroblastoma. They address the challenges and future prospects of commercializing these therapies, particularly for rare and pediatric cancers.
Discover the exciting developments in ALK-targeting CAR-T cells for neuroblastoma and new antigen-selected TIL therapies for head...2024-06-0707 minVJOncology PodcastBTOG 2024 HighlightsTune in to an insightful podcast hosted by VJOncology, featuring experts from BTOG 2024 discussing advancements in lung cancer research.
Prof. Charles Swanton (Francis Crick Institute, London, UK) delves into the link between air pollution and cancer development. Dr Thomas Newsom-Davies (Chelsea and Westminster Hospital NHS Foundation Trust, London, UK) highlights progress in TNM staging and immunotherapy. Dr Mariana Brandao (Institute Jules Bordet, Brussels, Belgium) addresses operability in non-small cell lung cancer, stressing the need for thorough assessments. Dr Robert Rintau (University of Cambridge & Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK) discusses implications of improved survival rates...2024-04-2624 minVJOncology PodcastUpdates in immunotherapy for head and neck cancerIn this podcast, we highlight some of the latest updates in the use of immunotherapy to treat head and neck cancer. This week we will be joined by Nicolas Mach, MD, Hôpitaux Universitaires de Genève, Geneva, Switzerland; Emrullah Yilmaz, MD, PhD, Cleveland Clinic, Cleveland, OH; Emrullah Yilmaz, MD, PhD, Cleveland Clinic, Cleveland, OH; Ari Rosenberg, MD, University of Chicago, Chicago, IL and Nabil Saba, MD, FACP, Winship Cancer Institute of Emory University, Atlanta, GA.
We will hear about the results of the SAKK 11/16 trial (NCT02999646) of the MVX-ONCO-1 vaccine, a Phase I dose expansion trial (NC...2024-03-2812 minVJOncology PodcastUpdates in immunotherapy for head and neck cancerIn this podcast, we highlight some of the latest updates in the use of immunotherapy to treat head and neck cancer. This week we will be joined by Nicolas Mach, MD, Hôpitaux Universitaires de Genève, Geneva, Switzerland; Emrullah Yilmaz, MD, PhD, Cleveland Clinic, Cleveland, OH; Emrullah Yilmaz, MD, PhD, Cleveland Clinic, Cleveland, OH; Ari Rosenberg, MD, University of Chicago, Chicago, IL and Nabil Saba, MD, FACP, Winship Cancer Institute of Emory University, Atlanta, GA.
We will hear about the results of the SAKK 11/16 trial (NCT02999646) of the MVX-ONCO-1 vaccine, a Phase I dose expansion trial (NC...2024-03-2812 minVJOncology PodcastUpdates in immunotherapy for skin cancerIn this podcast, we highlight some of the latest updates in the use of immunotherapy to treat skin cancer. This week, we will be joined by Omid Hamid, MD, The Angeles Clinic and Research Institute, Los Angeles, CA; Paolo Ascierto, MD, Istituto Tumori Fondazione Pascale, Naples, Italy; Georgina Long, PhD, MBBS, FRACP, FAHMS, The University of Sydney, North Sydney, Australia; and Karijn Suijkerbuijk, MD, PhD, UMC Utrecht, Utrecht, The Netherlands.
We will hear on the impact of T-Cell therapies, such as lifileucel, in patients with melanoma; results of the 7-year CheckMate 238 trial (NCT02388906) of nivolumab; effective sequencing...2024-03-2209 minVJOncology PodcastUpdates in immunotherapy for skin cancerIn this podcast, we highlight some of the latest updates in the use of immunotherapy to treat skin cancer. This week, we will be joined by Omid Hamid, MD, The Angeles Clinic and Research Institute, Los Angeles, CA; Paolo Ascierto, MD, Istituto Tumori Fondazione Pascale, Naples, Italy; Georgina Long, PhD, MBBS, FRACP, FAHMS, The University of Sydney, North Sydney, Australia; and Karijn Suijkerbuijk, MD, PhD, UMC Utrecht, Utrecht, The Netherlands.
We will hear on the impact of T-Cell therapies, such as lifileucel, in patients with melanoma; results of the 7-year CheckMate 238 trial (NCT02388906) of nivolumab; ef...2024-03-2209 minVJOncology PodcastTargeted therapies for lung cancer at TTLC 2024This week, we cover interesting research from TTLC 2024, focusing on innovative treatments for lung cancer. Starting off, Bruna Pellini from Moffitt Cancer Center, FL, talks about the utility of circulating tumor DNA as a biomarker of progression in lung cancer, her latest findings from notable Phase III trials and ongoing studies looking into increasing treatment based on this biomarker.
Next, Monica Chen from Memorial Sloan Kettering Cancer Center, NY, discusses the role of osimertinib with chemotherapy as initial treatment for patients with metastatic EGFR mutant lung cancers with concurrent TP53 and RB1 alterations from a clinical trial...2024-03-0119 minVJOncology PodcastLatest updates in mesotheliomaIn this latest episode from VJOncology, join us as we explore the latest news in mesothelioma research with three distinguished speakers. Anthony Chalmers, MD, University of Glasgow, Glasgow, UK, Dean Fennell, MBBS, PhD, FRCP, University Hospitals of Leicester NHS Trust, Leicester, UK, and Riyaz Shah, BSc(Hons), MBBS, FRCP, PhD, Kent Oncology Centre, UK. Discover the Phase II SYSTEMS-2 trial’s potential to reshape mesothelioma treatment and revolutionize patient care, unravel the excitement surrounding targeted therapy, particularly the TEAD inhibitor IK-930, showing great promise in disrupting cancer-promoting pathways, and finally learn more about the crucial role of immunotherapy in co...2023-08-0409 minVJOncology PodcastBreast Cancer Sessions: Highlights from SABCS 2022 with Sara Tolaney, Paolo Tarantino & Sarah SammonsThe San Antonio Breast Cancer Symposium (SABCS) 2022 took place on the 6-10th of December 2022 in San Antonio, TX. Leading experts in breast cancer came together to hear the latest clinical trial data and discuss how to improve care for patients with breast cancer.
In this podcast, we hear from Sara Tolaney, MD, MPH, Sarah Sammons, MD, and Paolo Tarantino, MD, of Dana-Farber Cancer Institute, Boston, MA, as they discuss the hot topics from SABCS 2022 in an exclusive roundtable discussion. Topics covered include updates on the use of the AKT inhibitor capivasertib, latest SERD data including elacestrant...2023-01-2726 minVJOncology PodcastBreast Cancer Sessions: Highlights from SABCS 2022 with Sara Tolaney, Paolo Tarantino & Sarah SammonsThe San Antonio Breast Cancer Symposium (SABCS) 2022 took place on the 6-10th of December 2022 in San Antonio, TX. Leading experts in breast cancer came together to hear the latest clinical trial data and discuss how to improve care for patients with breast cancer.
In this podcast, we hear from Sara Tolaney, MD, MPH, Sarah Sammons, MD, and Paolo Tarantino, MD, of Dana-Farber Cancer Institute, Boston, MA, as they discuss the hot topics from SABCS 2022 in an exclusive roundtable discussion. Topics covered include updates on the use of the AKT inhibitor capivasertib, latest SERD data including elacestrant...2023-01-2526 minVJOncology PodcastImpact of race on breast cancer outcomesBreast cancer is one of the leading causes of cancer mortality, with incidence, pathology, and clinical outcomes varying by geographical distribution as well as different racial and ethnic populations. Black, compared to White women with localized breast cancer have higher mortality and worse distant recurrence-free survival, which is often attributed to social determinants of health and higher prevalence of triple-negative breast cancer in black patients. In addition, racial and ethnic diversity in breast cancer clinical trials is lacking with both Blacks and Hispanics underrepresented.
In this podcast, we hear from Yara Abdou, MD, UNC School of Medicine...2023-01-0612 minVJOncology PodcastImpact of race on breast cancer outcomesBreast cancer is one of the leading causes of cancer mortality, with incidence, pathology and clinical outcomes varying by geographical distribution as well as different racial and ethnic populations. Black, compared to White women with localized breast cancer have higher mortality and worse distant recurrence-free survival, which is often attributed to social determinants of health and higher prevalence of triple-negative breast cancer in black patients. In addition, racial and ethnic diversity in breast cancer clinical trials is lacking with both Blacks and Hispanics underrepresented.
In this podcast, we hear from Yara Abdou, MD, UNC School o...2023-01-0612 minVJOncology PodcastEvolving role of ctDNA in breast cancerWith the advent of next-generation sequencing technologies, circulating tumor DNA (ctDNA) has now become an important player in the diagnosis, treatment, and management of breast cancer. In early breast cancer, the clearance of ctDNA is associated with improved pathological complete response following neoadjuvant therapy and may be important in treatment selection in patients with advanced disease. Continued efforts will likely lead to improvements in the use of liquid biopsy approaches and widespread routine clinical practice.
In this podcast, we will hear from Oleg Gluz, MD, Evang. Krankenhaus “”Bethesda”” Klinik, Mönchengladbach, Germany, Marla Lipsyc-Sharf, MD, Dana-Farber Cancer Institute...2022-10-2807 minVJOncology PodcastEvolving role of ctDNA in breast cancerWith the advent of next-generation sequencing technologies, circulating tumor DNA (ctDNA) has now become an important player in the diagnosis, treatment, and management of breast cancer. In early breast cancer, the clearance of ctDNA is associated with improved pathological complete response following neoadjuvant therapy and may be important in treatment selection in patients with advanced disease. Continued efforts will likely lead to improvements in the use of liquid biopsy approaches and widespread routine clinical practice.
In this podcast, we will hear from Oleg Gluz, MD, Evang. Krankenhaus “”Bethesda”” Klinik, Mönchengladbach, Germany, Marla Lipsyc-Sharf, MD, Dana-Farber Cancer Institute...2022-10-2607 minVJOncology PodcastESMO 2022 Daily Round-Ups: Day 4Catch up on our highlights from Day 4 of ESMO 2022!
We spoke to Toni Choueiri, Erika Hamilton, Jonathan Rosenberg, and Charles Swanton, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
The post ESMO 2022 Daily Round-Ups: Day 4 appeared first on VJOncology.
2022-09-1210 minVJOncology PodcastESMO 2022 Daily Round-Ups: Day 4Catch up on our highlights from Day 4 of ESMO 2022!
We spoke to Toni Choueiri, Erika Hamilton, Jonathan Rosenberg, and Charles Swanton, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
2022-09-1210 minVJOncology PodcastESMO 2022 Daily Round-Ups: Day 3Catch up on our highlights from Day 3 of ESMO 2022!
We spoke to Fabrice Andre, Fred Saad, and Solange Peters, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
The post ESMO 2022 Daily Round-Ups: Day 3 appeared first on VJOncology.
2022-09-1208 minVJOncology PodcastESMO 2022 Daily Round-Ups: Day 3Catch up on our highlights from Day 3 of ESMO 2022!
We spoke to Fabrice Andre, Fred Saad, and Solange Peters, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
2022-09-1208 minVJOncology PodcastESMO 2022 Daily Round-Ups: Day 2Catch up on our highlights from Day 2 of ESMO 2022!
We spoke to Dirk Schadendorf, Bjorn Henning Gronberg, Oleg Gluz, and Shaheenah Dawood, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
The post ESMO 2022 Daily Round-Ups: Day 2 appeared first on VJOncology.
2022-09-1119 minVJOncology PodcastESMO 2022 Daily Round-Ups: Day 2Catch up on our highlights from Day 2 of ESMO 2022!
We spoke to Dirk Schadendorf, Bjorn Henning Gronberg, Oleg Gluz, and Shaheenah Dawood, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
2022-09-1119 minVJOncology PodcastThe Lung Cancer Sessions: Updates from WCLC 2022The Lung Cancer Sessions from VJOncology aim to provide interesting perspectives from leading experts on the big topics in lung cancer research.
In this podcast, we hear from Lizza Hendriks of Maastricht University and Tiziana Vavala of the University of Turin as they discuss key updates from the IASLC World Congress on Lung Cancer in Vienna, Austria. Topics include the use of sotorasib in KRASG12C-mutant non-small cell lung cancer, oligometastatic disease, and key trial updates from the meeting.
The post The Lung Cancer Sessions: Updates from WCLC 2022 appeared first on VJOncology.
2022-09-0217 minVJOncology PodcastThe Lung Cancer Sessions: Updates from WCLC 2022The Lung Cancer Sessions from VJOncology aim to provide interesting perspectives from leading experts on the big topics in lung cancer research.
In this podcast, we hear from Lizza Hendricks of Maastricht University and Tiziana Vavala of the University of Turin as they discuss key updates from the IASLC World Congress on Lung Cancer in Vienna, Austria. Topics include the use of sotorasib in KRASG12C-mutant non-small cell lung cancer, oligometastatic disease, and key trial updates from the meeting.
2022-09-0217 minVJOncology PodcastTILs, Cancer Vaccines & the Future of Cellular Therapies in Melanoma with Allison Betof WarnerImmunotherapy plays a vital role in the management of patients with advanced-stage melanoma, and more recently, adoptive cell therapies and cancer vaccines have shown to be viable, novel treatment approaches able to induce complete and durable remissions in patients with melanoma.
In this exclusive podcast, VJOncology speaks to Allison Betof Warner, MD, PhD, from Memorial Sloan Kettering Cancer Center, New York, NY, who discusses the clinical potential of cellular therapies in the management of patients with melanoma, including the use of tumor-infiltrating lymphocyte (TIL) therapies as well as cancer vaccines and the next steps for these novel...2022-08-2606 minVJOncology PodcastTILs, Cancer Vaccines & the Future of Cellular Therapies in Melanoma with Allison Betof WarnerImmunotherapy plays a vital role in the management of patients with advanced-stage melanoma, and more recently, adoptive cell therapies and cancer vaccines have shown to be viable, novel treatment approaches able to induce complete and durable remissions in patients with melanoma.
In this exclusive podcast, VJOncology speaks to Allison Betof Warner, MD, PhD, from Memorial Sloan Kettering Cancer Center, New York, NY, who discusses the clinical potential of cellular therapies in the management of patients with melanoma, including the use of tumor-infiltrating lymphocyte (TIL) therapies as well as cancer vaccines and the next steps for these novel...2022-08-2606 minVJOncology PodcastASCO 2022 Daily Round-Ups: Day 3Catch up on our highlights from Day 3 of ASCO 2022!
We spoke to Jean-Pierre Gerard, Jonathan Rosenberg, Eva Segelov, Bruna Pellini, and Takayuki Yoshino, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
The post ASCO 2022 Daily Round-Ups: Day 3 appeared first on VJOncology.
2022-06-0514 minVJOncology PodcastASCO 2022 Daily Round-Ups: Day 2Catch up on our highlights from Day 2 of ASCO 2022!
We spoke to Joaquim Bellmunt, Robert Jones, Miguel Garcia-Pardo, and Ian Chau, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress.
The post ASCO 2022 Daily Round-Ups: Day 2 appeared first on VJOncology.
2022-06-0510 minVJOncology PodcastASCO 2022 Daily Round-Ups: Day 1Catch up on our highlights from Day 1 of ASCO 2022!
We spoke to Alexander Spira, Jia Luo, Paolo Ascierto, and Scott Tagawa, among many more! Keep an eye on VJOncology for more interviews, podcasts, and roundtable discussions throughout the congress
The post ASCO 2022 Daily Round-Ups: Day 1 appeared first on VJOncology.
2022-06-0404 minVJOncology PodcastBreast Cancer Sessions: Treatment de-escalation in TNBCThe development of complex and effective therapies has improved outcomes in breast cancer, highlighting the need for strategies to escalate and de-escalate treatment. In this exclusive VJSession, Roberto Salgado, MD (GZA Ziekenhuizen Campus Sint-Augustinus, Wilrijk, Belgium) and Marleen Kok, MD (Netherlands Cancer Institute, Amsterdam, Netherlands) discuss the latest advances in triple-negative breast cancer (TNBC), including treatment de-escalation and associated biomarkers, as well as the emerging role of tumor-infiltrating lymphocytes (TILs).
The Breast Cancer Podcasts on VJOncology are supported by Seagen. Seagen have no influence over the production of the content.
2022-05-2018 minVJOncology PodcastBreast Cancer Sessions: Treatment de-escalation in TNBCThe development of complex and effective therapies has improved outcomes in breast cancer, highlighting the need for strategies to escalate and de-escalate treatment. In this exclusive VJSession, Roberto Salgado, MD (GZA Ziekenhuizen Campus Sint-Augustinus, Wilrijk, Belgium) and Marleen Kok, MD (Netherlands Cancer Institute, Amsterdam, Netherlands) discuss the latest advances in triple-negative breast cancer (TNBC), including treatment de-escalation and associated biomarkers, as well as the emerging role of tumor-infiltrating lymphocytes (TILs).
The Breast Cancer Podcasts on VJOncology are supported by Seagen. Seagen have no influence over the production of the content.
The post Breast C...2022-05-2018 minVJOncology PodcastTrial updates from ESMO Breast Cancer 2022: TUXEDO-1, monarchE, KEYNOTE-355The European Society for Clinical Oncology (ESMO) Breast Cancer Conference was a hybrid event, held virtually and Berlin, Germany. This renowned meeting brought together global experts who disseminated the latest thinking in breast cancer.
VJOncology had the opportunity to speak to Rupert Bartsch, Medical University Vienna, Vienna, Austria, Paolo Tarantino, Dana Farber Cancer Institute, Boston, MA, and Dave Cescon, Princess Margaret Cancer Centre, Toronto, Canada, who discussed the latest trial updates in breast cancer, including updates from the TUXEDO-1 (NCT04752059), monarchE (NCT03155997) and KEYNOTE-355 (NCT02819518) studies.
The Breast Cancer Podcasts on VJOncology are supported by...2022-05-1605 minVJOncology PodcastTrial updates from ESMO Breast Cancer 2022: TUXEDO-1, monarchE, KEYNOTE-355The European Society for Clinical Oncology (ESMO) Breast Cancer Conference was a hybrid event, held virtually and Berlin, Germany. This renowned meeting brought together global experts who disseminated the latest thinking in breast cancer.
VJOncology had the opportunity to speak to Rupert Bartsch, Medical University Vienna, Vienna, Austria, Paolo Tarantino, Dana Farber Cancer Institute, Boston, MA, and Dave Cescon, Princess Margaret Cancer Centre, Toronto, Canada, who discussed the latest trial updates in breast cancer, including updates from the TUXEDO-1 (NCT04752059), monarchE (NCT03155997) and KEYNOTE-355 (NCT02819518) studies.
The Breast Cancer Podcasts on VJOncology are supported by...2022-05-1605 minVJOncology PodcastNovel treatment approaches in HR+/HER2- breast cancerResistance to endocrine therapy in patients with hormone-receptor positive (HR+), HER2-negative breast cancer inevitably results in relapse and metastasis, leading to death. Understanding mechanisms of intrinsic and acquired resistance has been the focus of many clinical studies. Recent advances including the use of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors and phosphoinositide 3-kinase (PI3K) inhibitors have improved progression-free survival and overall survival in these patients, however, endocrine resistance still develops in some patients. New classes of agents including oral selective estrogen receptor degraders (SERDs) and CDK7 inhibition have been explored in advanced HR+/HER2- metastatic breast cancer.
...2022-03-2508 minVJOncology PodcastThe GI Cancer Sessions: Highlights from ASCO GI 2022In this episode of the VJOncology podcast, a panel of leading gastrointestinal (GI) cancer experts offer their perspectives on the key GI cancer data presented at the 2022 ASCO GI Cancers Symposium, held in San Francisco, CA, in January 2022.
In this podcast, Nataliya Uboha, MD, PhD, University of Wisconsin, Madison, WI, is joined by Ghassan Abou-Alfa, MD, MBA, Memorial Sloan Kettering Cancer Center, New York, NY, and Kristen Ciombor, MD, MSci, Vanderbilt University Medical Center, Nashville, TN.
Listen to learn about the latest clinical research and practice-changing advances in GI cancers, including the evaluation of durvalumab...2022-03-0438 minVJOncology PodcastThe GI Cancer Sessions: Highlights from ASCO GI 2022In this episode of the VJOncology podcast, a panel of leading gastrointestinal (GI) cancer experts offer their perspectives on the key GI cancer data presented at the 2022 ASCO GI Cancers Symposium, held in San Francisco, CA, in January 2022.
In this podcast, Nataliya Uboha, MD, PhD, University of Wisconsin, Madison, WI, is joined by Ghassan Abou-Alfa, MD, MBA, Memorial Sloan Kettering Cancer Center, New York, NY, and Kristen Ciombor, MD, MSci, Vanderbilt University Medical Center, Nashville, TN.
Listen to learn about the latest clinical research and practice-changing advances in GI cancers, including the evaluation of durvalumab...2022-03-0438 minVJOncology PodcastUpdates on HER2-positive breast cancerHER2-positive breast cancer accounts for 15-20% of all breast cancer cases. It was associated with a poor prognosis until the approval of trastuzumab, a monoclonal antibody targeting HER2. Since then, the therapeutic landscape for patients with HER2-positive tumors has changed dramatically, with the introduction of other monoclonal antibodies such as pertuzumab, tyrosine kinase inhibitors including lapatinib and neratinib, and the antibody-drug conjugate trastuzumab emtansine (T-DM1). Currently, patients with HER2-positive breast cancer are treated with a taxane plus trastuzumab in the first-line setting and with T-DM1 in second-line. Several treatments are emerging as viable options for the...2022-02-1507 minVJOncology PodcastBreast Cancer Sessions: Highlights from SABCS 2021 with Lisa Carey & Aleix PratThe San Antonio Breast Cancer Symposium 2021 featured exciting developments in early and advanced breast cancer, basic science, and translational research.
In this podcast, we had the opportunity to hear from Lisa A. Carey (UNC Lineberger, Chapel Hill, NC) and Aleix Prat (Hospital Clínic Barcelona, Barcelona, Spain) who discuss advances in breast cancer care and management, including highlights from the meeting, as well as recent updates from the MONALEESA studies.
The Breast Cancer Podcasts on VJOncology are supported by Seagen. Seagen have no influence over the production of the content.
The post Breast C...2022-01-1416 minVJOncology PodcastBreast Cancer Sessions: Highlights from SABCS 2021 with Lisa Carey & Aleix PratThe San Antonio Breast Cancer Symposium 2021 featured exciting developments in early and advanced breast cancer, basic science, and translational research.
In this podcast, we had the opportunity to hear from Lisa A. Carey (UNC Lineberger, Chapel Hill, NC) and Aleix Prat (Hospital Clínic Barcelona, Barcelona, Spain) who discuss advances in breast cancer care and management, including highlights from the meeting, as well as recent updates from the MONALEESA studies.
The Breast Cancer Podcasts on VJOncology are supported by Seagen. Seagen have no influence over the production of the content.
2022-01-1416 minVJOncology PodcastImmunotherapy updates from SABCS 2021 with Heather McArthur & Kevin KalinskyThe success of immunotherapy in the treatment of solid tumors has created hope for its potential in breast cancer. The San Antonio Breast Cancer Symposium 2021 showcased an array of updates in breast cancer care and management, including updates on pivotal trials evaluating the use of immunotherapy in breast cancer.
In this podcast, we hear from leading experts, Kevin Kalinsky (Emory University, Atlanta, GA) and Heather McArthur (UT Southwestern Medical Center, Dallas, TX) who discuss the latest advances in immunotherapy for breast cancer presented at the hybrid SABCS 2021 meeting and what the latest research means for the clinic.2022-01-0417 minVJOncology PodcastThe Lung Cancer Sessions: Advances in EGFR-mutated NSCLCThe Lung Cancer Sessions from VJOncology aim to provide interesting perspectives from leading experts on the big topics in lung cancer research. In this podcast, Ross Camidge, MD, PhD, of University of Colorado, Aurora, CO, chairs a lively discussion on the latest advances and standard clinical practices in EGFR-mutated NSCLC, including EGFR testing, options for first-line treatment, and developments in immunotherapy.
He is joined by Rosario Garcia Campelo, MD, of Coruña University Hospital, A Coruña, Spain, Natasha Leighl, MD, MMSc, FRCPC, of Princess Margaret Cancer Center, Toronto, Canada, and Alexander Spira, MD, PhD, FAC...2021-11-2544 minVJOncology PodcastThe Lung Cancer Sessions: Advances in EGFR-mutated NSCLCThe Lung Cancer Sessions from VJOncology aim to provide interesting perspectives from leading experts on the big topics in lung cancer research. In this podcast, Ross Camidge, MD, PhD, of University of Colorado, Aurora, CO, chairs a lively discussion on the latest advances and standard clinical practices in EGFR-mutated NSCLC, including EGFR testing, options for first-line treatment, and developments in immunotherapy.
He is joined by Rosario Garcia Campelo, MD, of Coruña University Hospital, A Coruña, Spain, Natasha Leighl, MD, MMSc, FRCPC, of Princess Margaret Cancer Center, Toronto, Canada, and Alexander Spira, MD, PhD, FAC...2021-11-2544 minVJOncology PodcastThe GU Cancer Sessions: Bladder Highlights from ESMO 2021VJOncology has assembled a group of leading genitourinary cancer experts to examine and discuss the latest developments in bladder cancer presented at the European Society for Medical Oncology (ESMO) 2021 Annual Meeting.
Listen to this insightful roundtable discussion featuring Laurence Albiges, Gustave Roussy Institute, Villejuif, France, and Enrique Grande, MD Anderson Cancer Center Madrid, Madrid, Spain, to hear about ground-breaking erdafitinib data from NORSE in metastatic or locally advanced urothelial carcinoma, as well as VESPER in muscle-invasive bladder cancer (MIBC). They additionally examine innovative data on pembrolizumab in combination with anti- Ephrin-B2 sEphB4-HSA in advanced urothelial carcinoma....2021-10-1922 minVJOncology PodcastThe GU Cancer Sessions: Bladder Highlights from ESMO 2021VJOncology has assembled a group of leading genitourinary cancer experts to examine and discuss the exciting developments in bladder cancer presented at the European Society for Medical Oncology (ESMO) 2021 Annual Meeting.
Listen to this insightful roundtable discussion featuring Laurence Albiges, Gustave Roussy Institute, Villejuif, France, and Enrique Grande, MD Anderson Cancer Center Madrid, Madrid, Spain, to hear about ground-breaking erdafitinib data from NORSE in metastatic or locally advanced urothelial carcinoma, as well as VESPER in muscle-invasive bladder cancer (MIBC). They additionally examine innovative data on pembrolizumab in combination with anti- Ephrin-B2 sEphB4-HSA in advanced urothelial carcinoma.2021-10-1922 minVJOncology PodcastThe Skin Cancer Sessions: Highlights from ASCO 2021VJOncology has assembled a panel of world-renowned skin cancer experts to examine and discuss the exciting advances in skin cancer presented at the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting.
In this exclusive podcast, James Larkin, MD, PhD, Royal Marsden Hospital, London, UK, is joined by Rodabe Amaria, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, Ana Arance, MD, PhD, Hospital Clínic de Barcelona, Barcelona, Spain, and Paolo Ascierto, MD, National Tumor Institute, Milan, Italy.
Listen to this insightful roundtable discussion to learn about the latest clinical trial data in s...2021-10-0752 minVJOncology PodcastThe Lung Cancer Sessions: Highlights from ASCO 2021Following the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, VJOncology brought together a group of leading lung cancer experts to offer their perspectives on the latest research advances presented at the meeting and how they could impact lung cancer care in the future.
In this exclusive post-ASCO podcast, Melissa Johnson, MD, Sarah Cannon Research Institute, Nashville, TN, is joined by Lizza Hendriks, MD, PhD, Maastricht University, Maastricht, Netherlands, and Heather Wakelee, MD, Stanford University, Stanford, CA, as they delve into the latest practice-changing lung cancer data.
Listen to this esteemed panel discuss adjuvant trials...2021-10-0739 minVJOncology PodcastThe GI Cancer Sessions: Highlights from ASCO 2021At the virtual 2021 American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, important advances and potentially practice-changing trial data were presented in a range of gastrointestinal (GI) malignancies such as esophageal, gastric and colorectal cancer. VJOncology has assembled an esteemed panel of leading GI experts to discuss the latest exciting developments, what these advances could actually mean for clinical practice in the future and what still needs to be done.
Tobias Arkenau, MD, PHD, Sarah Cannon Research Institute UK, London, UK, chairs this roundtable discussion and is joined by:
Deborah Mukherji, MBBS, FRCP, American University of Beirut...2021-10-0757 minVJOncology PodcastThe Lung Cancer Sessions: Highlights from ASCO 2021Following the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, VJOncology brought together a group of leading lung cancer experts to offer their perspectives on the latest research advances presented at the meeting and how they could impact lung cancer care in the future.
In this exclusive post-ASCO podcast, Melissa Johnson, MD, Sarah Cannon Research Institute, Nashville, TN, is joined by Lizza Hendriks, MD, PhD, Maastricht University, Maastricht, Netherlands, and Heather Wakelee, MD, Stanford University, Stanford, CA, as they delve into the latest practice-changing lung cancer data.
Listen to this esteemed panel discuss adjuvant trials...2021-09-2239 minVJOncology PodcastThe GI Cancer Sessions: Highlights from ASCO 2021At the virtual 2021 American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, important advances and potentially practice-changing trial data were presented in a range of gastrointestinal (GI) malignancies such as esophageal, gastric and colorectal cancer. VJOncology has assembled an esteemed panel of leading GI experts to discuss the latest exciting developments, what these advances could actually mean for clinical practice in the future and what still needs to be done.
Tobias Arkenau, MD, PHD, Sarah Cannon Research Institute UK, London, UK, chairs this roundtable discussion and is joined by:
Deborah Mukherji, MBBS, FRCP, American University of Beirut...2021-09-2257 minVJOncology PodcastThe Skin Cancer Sessions: Highlights from ASCO 2021VJOncology has assembled a panel of world-renowned skin cancer experts to examine and discuss the exciting advances in skin cancer presented at the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting.
In this exclusive podcast, James Larkin, MD, PhD, Royal Marsden Hospital, London, UK, is joined by Rodabe Amaria, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, Ana Arance, MD, PhD, Hospital Clínic de Barcelona, Barcelona, Spain, and Paolo Ascierto, MD, National Tumor Institute, Milan, Italy.
Listen to this insightful roundtable discussion to learn about the latest clinical trial data in s...2021-09-2252 minVJOncology PodcastThe Breast Cancer Sessions: Highlights from ASCO 2021VJOncology has assembled an international panel of leading breast cancer experts to discuss the latest advances and data from the virtual American Society of Clinical Oncology (ASCO) 2021 Annual Meeting.
In this podcast, Erika Hamilton, MD, Sarah Cannon Research Institute, Nashville, TN, is joined by Giuseppe Curigliano, MD, University of Milan, Milan, Italy, Sara Tolaney, MD, MPH, Dana-Farber Cancer Institute, Boston, MA, and Andrew Tutt, MBChB, PhD, The Institute of Cancer Research, London, UK, to examine the recent major breakthroughs in breast cancer and what they mean for clinical practice.
Tune in to hear the expert...2021-08-1839 minVJOncology PodcastThe GU Cancer Sessions: Bladder and Kidney Highlights from ASCO 2021During the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, an exciting array of advances in genitourinary (GU) cancer research were presented. VJOncology has brought together a panel of leading GU experts to consider and debate the latest developments in bladder and kidney cancer and offer their perspectives on how they could impact patient care in the future.
This post-ASCO GU cancer roundtable discussion is chaired by Elizabeth Plimack, MD, MS, from the Fox Chase Cancer Center, Philadelphia, PA, who is joined by Rana McKay, MD, University of California San Diego, San Diego, CA, and Thomas Powles, M...2021-08-1831 minVJOncology PodcastThe GU Cancer Sessions: Bladder and Kidney Highlights from ASCO 2021During the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, an exciting array of advances in genitourinary (GU) cancer research were presented. VJOncology has brought together a panel of leading GU experts to consider and debate the latest developments in bladder and kidney cancer and offer their perspectives on how they could impact patient care in the future.
This post-ASCO GU cancer roundtable discussion is chaired by Elizabeth Plimack, MD, MS, from the Fox Chase Cancer Center, Philadelphia, PA, who is joined by Rana McKay, MD, University of California San Diego, San Diego, CA, and Thomas Powles, MB...2021-08-1631 minVJOncology PodcastThe Breast Cancer Sessions: Highlights from ASCO 2021VJOncology has assembled an international panel of leading breast cancer experts to discuss the latest advances and data from the virtual American Society of Clinical Oncology (ASCO) 2021 Annual Meeting.
In this podcast, Erika Hamilton, MD, Sarah Cannon Research Institute, Nashville, TN, is joined by Giuseppe Curigliano, MD, University of Milan, Milan, Italy, Sara Tolaney, MD, MPH, Dana-Farber Cancer Institute, Boston, MA, and Andrew Tutt, MBChB, PhD, The Institute of Cancer Research, London, UK, to examine the recent major breakthroughs in breast cancer and what they mean for clinical practice.
Tune in to hear the expert...2021-08-1639 minVJOncology PodcastWhat’s new? Treating breast cancer with brain metastasesMetastatic breast cancer is breast cancer that has spread to other regions of the body, most commonly the liver, brain, bones, or lungs. Although significant developments have been made in the treatment options available for patients with metastatic breast cancer, the occurrence of brain metastases remains a substantial clinical challenge.
The incidence and prognosis of patients with brain metastases related to breast cancer varies by subtype. Triple negative disease has the highest rates, occurring in as many as 46% of cancers, compared to 35% and 14% in HER2-positive and hormone receptor (HR)-positive disease, respectfully. Brain metastases are not...2021-07-1311 minVJOncology PodcastGlobal breast cancer careHealthcare systems around the world differ in financial and political situations. Therefore, it is vital to implement a global outlook of breast cancer care that focuses on applying access to high-quality practices, especially in low- and middle-income countries, where breast cancer remains a public health crisis.
During this podcast, Andre Ilbawi, MD, of the World Health Organization (WHO), Carol Benn, MBBCh, FCS, of the Breast Care Center of Excellence, Milpark Hospital in Johannesburg, South Africa, and Cynthia Villareal-Garza, MD, DSc, of the Mexican National Cancer Institute & Tecnologico de Monterrey, Mexico discuss the latest information on global breast...2021-07-1312 minVJOncology PodcastThe Lung Cancer Sessions: Highlights from BTOG 2021VJOncology has assembled a panel of leading experts, who offer their perspectives on the latest developments in lung cancer presented at the 19th British Thoracic Oncology Group (BTOG) Annual Conference 2021.
In this podcast, Sanjay Popat, BSc, MBBS, FRCP, PhD, The Royal Marsden NHS Foundation Trust London, UK, is joined by Samreen Ahmed, MBBS, MSc(onc), FRCP, MD, University Hospitals of Leicester Trust, Leicester, UK, David Gilligan, MBChB, FRCPE, FRCR, Addenbrooke’s & Papworth Hospitals, Cambridge, UK and Neal Navani, MBBS, PhD, University College London Hospitals NHS Foundation Trust, London, UK.
Tune in to hear the expert pa...2021-06-2248 minVJOncology PodcastESMO Breast 2021: updates on immunotherapyBreast cancer is the most common type of cancer in women. Although most cases of early-stage non-metastatic disease are curable with surgery, effective treatments for later-stage and metastatic disease remain an unmet need. Several immunotherapies have received FDA approval for the treatment of breast cancer, including pembrolizumab, atezolizumab and trastuzumab deruxtecan.
In this podcast, Rebecca Dent, MD, FRCP, of the National Cancer Centre Singapore, Rupert Bartsch, MD, of the Medical University of Vienna in Austria, and Marleen Kok, MD, PhD, of the Netherlands Cancer Institute in Amsterdam, discuss key updates on immunotherapies for the treatment of breast...2021-06-1014 minVJOncology PodcastThe Lung Cancer Sessions: Highlights from BTOG 2021VJOncology has assembled a panel of world-renowned experts, who offer their perspectives on the latest developments in lung cancer presented at the 19th British Thoracic Oncology Group (BTOG) Annual Conference 2021.
In this podcast, Sanjay Popat, BSc, MBBS, FRCP, PhD, The Royal Marsden NHS Foundation Trust London, UK, is joined by Samreen Ahmed, MBBS, MSc(onc), FRCP, MD, University Hospitals of Leicester Trust, Leicester, UK, David Gilligan, MBChB, FRCPE, FRCR, Addenbrooke's & Papworth Hospitals, Cambridge, UK and Neal Navani, MBBS, PhD, University College London Hospitals NHS Foundation Trust, London, UK.
Tune in to hear the expert panel d...2021-06-0348 minVJOncology PodcastThe GU Cancer Sessions: Bladder and Kidney Highlights from ASCO GU 2021VJOncology has assembled a panel of leading experts, who offer their perspectives on the latest bladder and kidney cancer data presented at the American Society of Clinical Oncology (ASCO) Genitourinary Cancer Symposium, which was held virtually in February 2021.
In this podcast, Arlene Siefker-Radtke, MD, University of Texas MD Anderson Cancer Center, Houston, TX, is joined by Alison Birtle, MRCP, FRCR, MD, Lancashire Teaching Hospitals, Preston, UK, Andrea Apollo, MD, National Cancer Institute, Bethesda, MD, and Thomas Powles, MBBS, MRCP, Barts Cancer Institute, London, UK.
Tune in to learn more about the latest clinical trial data...2021-05-1442 minVJOncology PodcastSequencing HER2-targeting therapies in the metastatic breast cancer spaceTreatment approaches in breast cancer are multimodal, and with the onset of novel immunotherapies and targeted agents, the therapeutic landscape of patients with advanced disease has expanded. In HER2+ disease, the treatment landscape has become saturated with novel HER2-targeting agents, bringing into question how these agents should be sequenced for maximum benefit to patients.
In this podcast, we spoke with three leading experts in breast cancer who discuss the optimal sequencing of HER2-targeted therapies such as T-DM1, neratinib, tucatinib, and margetuximab. Join Lisa Carey, MD, The University of North Carolina at Chapel Hill, Chapel Hill...2021-05-1413 minVJOncology PodcastThe GU Sessions: Prostate Cancer Highlights from ASCO GU 2021The 2021 American Society of Clinical Oncology (ASCO) Genitourinary Cancer Symposium showcased a range of exciting clinical trial data and major milestones in prostate cancer. VJOncology has bought together a team of leading experts in prostate cancer to explore their insights on key updates from this meeting.
In this exclusive podcast, Neal Shore, MD, FACS, Carolina Urologic Research Center, SC was joined by Bertrand Tombal, MD, PhD, Cliniques Universataires Saint-Luc, Brussels, Belgium, Rana McKay, MD, UC San Diego Health, CA, and Robert Jones, MBChB, PhD, University of Glasgow & Beaston West of Scotland Cancer Center, Glasgow, UK.
...2021-05-1352 minVJOncology PodcastThe GU Cancer Sessions: Bladder and Kidney Highlights from ASCO GU 2021VJOncology has assembled a panel of leading experts, who offer their perspectives on the latest bladder and kidney cancer data presented at the American Society of Clinical Oncology (ASCO) Genitourinary Cancer Symposium, which was held virtually in February 2021.
In this podcast, Arlene Siefker-Radtke, MD, University of Texas MD Anderson Cancer Center, Houston, TX, is joined by Alison Birtle, MRCP, FRCR, MD, Lancashire Teaching Hospitals, Preston, UK, Andrea Apollo, MD, National Cancer Institute, Bethesda, MD, and Thomas Powles, MBBS, MRCP, Barts Cancer Institute, London, UK.
Tune in to learn more about the latest clinical trial data...2021-05-1342 minVJOncology PodcastThe GU Sessions: Prostate Cancer Highlights from ASCO GU 2021The 2021 American Society of Clinical Oncology (ASCO) Genitourinary Cancer Symposium showcased a range of exciting clinical trial data and major milestones in prostate cancer. VJOncology has bought together a team of leading experts in prostate cancer to explore their insights on key updates from this meeting.
In this exclusive podcast, Neal Shore, MD, FACS, Carolina Urologic Research Center, SC was joined by Bertrand Tombal, MD, PhD, Cliniques Universataires Saint-Luc, Brussels, Belgium, Rana McKay, MD, UC San Diego Health, CA, and Robert Jones, MBChB, PhD, University of Glasgow & Beaston West of Scotland Cancer Center, Glasgow, UK.
...2021-05-1352 minVJOncology PodcastPredictive and prognostic biomarkers in breast cancerFollowing a breast cancer diagnosis, the most immediate challenges in patient management are the determination of prognosis and identification of the most appropriate adjuvant systemic therapy, the most valid of these tests include Oncotype DX and MammaPrint. In the identification of new predictive and prognostic markers, research efforts are focusing on the clinical utility of circulating and tumor DNA as well as the predictive significance of tumor-infiltrating lymphocytes (TILs).
In this exclusive podcast, VJOncology spoke with Judy Garber, MD, MPH, of the Dana-Farber Cancer Institute, Boston, MA, Martine Piccart, MD, PhD, of the Université Libre de...2021-04-0710 minVJOncology PodcastPredictive and prognostic biomarkers in breast cancerFollowing a breast cancer diagnosis, the most immediate challenges in patient management are the determination of prognosis and identification of the most appropriate adjuvant systemic therapy, the most valid of these tests include Oncotype DX and MammaPrint. In the identification of new predictive and prognostic markers, research efforts are focusing on the clinical utility of circulating and tumor DNA as well as the predictive significance of tumor-infiltrating lymphocytes (TILs).
In this exclusive podcast, VJOncology spoke with Judy Garber, MD, MPH, of the Dana-Farber Cancer Institute, Boston, MA, Martine Piccart, MD, PhD, of the Université Libre de Bruxelles, B...2021-04-0710 minVJOncology PodcastThe Lung Cancer Sessions: highlights from IASLC WCLCVJOncology has assembled an international panel of leading experts in lung cancer and mesothelioma to bring you the key highlights from the IASLC World Conference on Lung Cancer (WCLC), which was held virtually in January 2021.
Daniel Tan (National Cancer Centre Singapore, Singapore) is joined by Melissa Johnson (Sarah Cannon Research Institute, TN) and Dean Fennell (University Hospitals of Leicester NHS Trust, UK), who offer their perspectives on the exciting data and what research could change practice in the future.
Tune in to this podcast to learn about the latest advances in KRAS G12C inhibitors...2021-02-1846 minVJOncology PodcastSABCS 2020 highlights: immunotherapy, novel agents & trial updatesIn December, the San Antonio Breast Cancer Symposium (SABCS) 2020 convened virtually and featured key updates in the treatment and management of breast cancer, including the latest data in immune-oncology, novel targeted therapies, and many highly anticipated trial updates.
In this podcast, Sangeetha Reddy, MD, of UT Southwestern Medical Center, Dallas, TX, Bora Lim, of The University of Texas MD Anderson Cancer Center, Houston, TX, and Matteo Lambertini, MD, PhD of IRCCS AOU San Martino (Ospedale Policlinico San Martino), Genova, Italy, discuss treatment approaches in breast cancer, including the latest trial data, as well as immunotherapy and targeted...2021-01-0815 minVJOncology PodcastKey trial updates at SABCS 2020: monarchE, RxPONDER & ASCENTThe San Antonio Breast Cancer Symposium (SABCS) 2020 annual meeting took place virtually this year and showcased recent advances in the treatment and management of breast cancer.
In this podcast, Priya Rastogi, MD, of the University of Pittsburgh, Pittsburgh, PA, Sara M. Tolaney, MD, MPH, of the Dana-Farber Cancer Institute, Boston, MA, and Sara Hurvitz, MD, of Ronald Reagan UCLA Medical Center, Los Angeles, CA, outline key trial updates presented at SABCS 2020, including the primary outcome results of the monarchE study (NCT02107703), the practice-changing findings of RxPONDER (NCT01272037), and the updated biomarker analysis of the ASCENT study (NCT02574455...2020-12-1510 minVJOncology PodcastUpdates in non-small cell lung cancer from ESMOSignificant advances have been made in the treatment of non-small cell lung cancer (NSCLC), the most common form of lung cancer. The latest trial updates in oncogene-targeted therapy for patients with advanced ALK-positive NSCLC were presented during the European Society for Medical Oncology (ESMO) 2020 Virtual Congress.
In a planned interim analysis of the Phase III CROWN trial, lorlatinib significantly improved progression-free survival compared with crizotinib. Additionally, insights from sub-analyses of the Phase III ALTA 1L study support the evidence of intracranial efficacy with brigatinib for patients with ALK-positive NSCLC as well as associated quality of life data.2020-11-0309 minVJOncology PodcastHighlights from EADO 2020: novel therapies, neoadjuvant approaches & COVID-19The 16th European Association of Dermato-Oncology (EADO) meeting took place virtually this year and provided an opportunity to hear from worldwide recognized experts in the field of skin cancers and melanoma, as well as the impact of the COVID-19 pandemic on cancer care.
In this podcast, Michael Postow, MD, of Memorial Sloan Kettering Cancer Center, New York, NY, Alexander van Akkooi, MD, PhD, of Netherlands Cancer Institute, Amsterdam, The Netherlands, and Bettina Ryll, MD, PhD, of the Melanoma Patient Network Europe, Uppsala, Sweden, discuss novel therapies in melanoma, neoadjuvant approaches and the impact of COVID-19 on the...2020-10-2918 minVJOncology PodcastThe ONS/EONS Congress Roundtable Discussion with VJOncology and OncoAlertThe treatment of cancer continues to evolve rapidly, with expanded therapeutic options and changes to clinical practice. Additionally, the care of patients with cancer has been complicated in 2020 by the COVID-19 pandemic. Oncology nurses are at the forefront of cancer care, looking after patients and their carers day-to-day. It is therefore vital to share information and educate nurses to maintain their knowledge and skills, to ensure the best care for their patients.
In this podcast, Gilberto Morgan, MD, Skåne University Hospital, Lund, Sweden, chairs a thoughtful discussion with Darcy Burbage, DNP, RN, AOCN, CBCN, Oncology Clinical N...2020-09-1047 minVJOncology PodcastThe ONS/EONS Congress Roundtable Discussion with VJOncology and OncoAlertThe treatment of cancer continues to evolve rapidly, with expanded therapeutic options and changes to clinical practice. Additionally, the care...
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2020-09-1047 minVJOncology PodcastPrioritizing patients for breast cancer surgery during COVID-19Patients with cancer consistently demonstrate poorer post-COVID-19 infection outcomes, and as a result of the pandemic, cancer services within the UK have shifted to protect patient survival. In the breast cancer field, the surgical management of primary breast cancer has also been affected, with many ER+ HER2- patients being deferred from surgery to neoadjuvant endocrine therapy due to safety concerns and resource availability. Therefore, the identification of primary breast cancer patients at greater need for surgical intervention is of great importance.
In this podcast, Peter Barry MBBS (Hons), MPhil, FRACS, Royal Marsden NHS Foundation Trust, London...2020-08-0318 minVJOncology PodcastGenotyping in lung cancer and multi-cancer detectionUsing precision genotyping for identifying resistance mechanisms in advanced lung cancer can help guide treatment decisions and prolong the benefit of targeted therapy. Advancements in the use of circulating tumor cell-free DNA (cfDNA) has simplified this procedure to look for multiple mutations, although further tests are usually needed to confirm the mutation present.
The use of cfDNA has also been evaluated for the detection of multiple cancer types, and a recent publication in the Annals of Oncology showed that over 50 cancer subtypes can be successfully detected, paving the way for earlier detection, earlier treatment and potentially higher...2020-07-0109 min