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Vijay S. Pande

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a16z Podcasta16z PodcastWhat Super Agers Reveal About Preventing DiseaseAmerican healthcare is in crisis—but what if we could change the system by preventing disease before it starts?In this episode of the a16z Podcast, general partner Vijay Pande sits down with Dr. Eric Topol, founder and director of the Scripps Research Translational Institute and one of the most cited researchers in medicine, to explore the cutting edge of preventive healthcare and longevity science.Drawing from his new book Super Agers: An Evidence-Based Path to Longevity, Topol breaks down why understanding the biology of aging—not reversing it—is the key to preventing the “B...2025-05-1442 mina16z Podcasta16z PodcastMarc Andreessen: Can Tech Finally Fix Healthcare?Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyrocketing costs. Why is this the case, and what will it take to fix it?In this episode, a16z cofounder Marc Andreessen and General Partners Vijay Pande and Julie Yoo tackle some of the biggest questions shaping the future of healthcare:Is the solution to our healthcare crisis a policy, technology, or competition problem?Will AI and technology transform the industry, or ar...2025-01-1532 minTranslating ProteomicsTranslating ProteomicsAI and Biotech - The Promise and the Pitfalls with Matt McIlwain and Vijay PandeParag Mallick discusses the role of AI and machine learning in biotech with special guests Vijay Pande from Andreessen Horowitz and Matt McIlwain from Madrona Venture Group. Their fascinating conversation covers:Advances that have enabled biotech to make use of AI and machine learningHow founders are applying AI and machine learning in biotechThe future of AI and machine learning in biotechChapters00:00 - Introduction04:37 - How did Vijay and Matt get into AI and ML07:33 - The importance of structured data, advances in compute, and algorithmic advances in driving the...2024-12-0453 mina16z Podcasta16z PodcastThe Longevity Imperative: Redefining the Way We AgeWhat if the biggest challenge of our time isn’t living longer, but living better? In this episode, we’re tackling one of humanity’s greatest accomplishments—and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems—healthcare, finance, career planning, and even our cultural perceptions of aging—need a fundamental overhaul. We’re joined by Dr. Andrew Scott, author of The Longevity Imperative, and Vijay Pande a16z’s Bio & Health general partner, to explore how a shift from “sick care” to “health care” could transform our lives. Together, we discuss the implications o...2024-11-1840 minRaising HealthRaising HealthWhy Tech Must Disrupt Healthcare NowIn this episode, Vijay Pande and Daisy Wolf of a16z Bio + Health join a16z Podcast host Steph Smith to make a provocative case for why technologists—not just medical professionals—are key to reinventing healthcare. They argue that to transform a sector representing 20% of U.S. GDP, innovation must move beyond curing diseases toward tackling healthcare’s broken systems. By likening the healthcare industry to a logistics challenge, Vijay and Daisy outline how technologists can leverage their expertise in consumer engagement, operational efficiency, and AI to drive the next frontier of health innovation. They also explore...2024-10-0842 minRaising HealthRaising HealthAI + a16z with Vijay PandeVijay Pande, PhD, founding partner of a16z Bio + Health, joins Derrick Harris, host of the AI + a16z podcast. Together, they discuss how computer science has subsumed biotech. 2024-09-1048 mina16z Podcasta16z PodcastGrand Challenges in Healthcare AIVijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to discuss the grand challenges facing healthcare AI today.The talk through the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the opportunity for innovation in clinical trials. They also talk about the AI startup they each wish would walk through the door.  Resources: Find Vijay on Twitter: https://x.com/vijaypandeFInd Julie on Twitter: https://x.com/julesyooListen to mor...2024-09-0737 minNEJM AI Grand RoundsNEJM AI Grand RoundsFrom Petri Dishes to Pitch Decks: Cultivating Health Care’s AI Future with Vijay PandeIn this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Vijay Pande, a general partner at Andreessen Horowitz (A16Z) where he leads investments in health care and life sciences. The conversation explores Pande’s journey from academia to venture capital, his views on the future of AI in health care and biomedicine, and insights into the investment landscape for biotech and health tech companies. Pande discusses the challenges and opportunities in integrating AI into medical practice, the potential for AI to democratize health care access, and his thoughts on the development of ar...2024-08-2154 minRaising HealthRaising HealthAI at the Intersection of Bio with Vijay Pande, Surya Ganguli, and Bowen LiuBowen Liu, PhD, investing partner, and Surya Ganguli, PhD, venture partner, join Vijay Pande, PhD, general partner of a16z Bio + Health.Together, they detail different methods through which AI could assist drug development, the opportunity for AI to flag new targets and compounds for scientists to investigate, and the science fiction-sounding notion of developing a foundation model that untangles biology.This is an in-depth conversation from three AI experts and biologists, so we’ll also publish the transcript alongside the episode on our website if you want to follow along.  2024-08-1330 minAI + a16zAI + a16zWhy Computer Science Subsumed BiotechIn this episode, a16z General Partner Vijay Pande walks us through the past two decades of applying software engineering to the life sciences — from the Folding@Home project that he launched, through AlphaFold and more. He also discusses the major opportunities for AI to transform medicine and health care, as well as some pitfalls that founders in that space need to watch out for.Here's an excerpt of Vijay discussing how AlphaFold and other projects revolutionized biology research not just because of their algorithms, but because of how they introduced software engineering into the field:...2024-08-0947 minRaising HealthRaising HealthImplementation, Data, Impact of Healthcare AI with Vijay Pande and Julie YooIn this episode, a follow-up to our episode Grand Challenges in Healthcare AI, Julie Yoo and Vijay Pande, a16z general partners, answer audience questions about AI applications in healthcare.Together, they dive into cost and implementation challenges, the data landscape, and what the patient experience might look like.If you liked this episode, listen to Grand Challenges in Healthcare AI here or wherever you get your podcasts. 2024-07-3035 minThe Dr. Hyman ShowThe Dr. Hyman ShowThe Future of Healthcare: The Role of AI and Technology | Dr. Vijay Pande and Daisy WolfView Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. HymanSign Up for Dr. Hyman’s Weekly Longevity JournalAI is set to revolutionize healthcare as we know it - improving diagnostics, treatment personalization, patient care, while simultaneously reducing costs and enhancing outcomes. In this episode of “The Doctor’s Farmacy,” I sit down with Vijay Pande, PhD and Daisy Wolf, JD to explore how investors are shaping the future by funding innovative companies that address our system's fundamental problems. Discover how cutting-edge tech, like wearable devices and AI diagnost...2024-06-2559 mina16z Podcasta16z PodcastCan AI Advance Science? DeepMind's VP of Science Weighs InIn recent years, the AI landscape has seen huge advancements, from the release of Dall-E 2 in April 2022 to the emergence of AI music and video models in early 2024.While creative tools often steal the spotlight, AlphaFold 2 marked a groundbreaking AI breakthrough in biology in 2021. Since its release, this pioneering tool for predicting protein structures has been utilized by over 1.7 million scientists worldwide, influencing fields ranging from genomics to computational chemistry.In this episode, DeepMind's VP of Research for Science, Pushmeet Kohli, and a16z General Partner Vijay Pande discuss the transformative potential of AI in...2024-05-0155 minRaising HealthRaising HealthGrand Challenges in Healthcare AI with Vijay Pande and Julie YooVijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to talk through the grand challenges facing healthcare AI today.The discussion covers the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the potential for innovation in clinical trials. They also talk about the AI startup they each wish would walk through the door.  2024-04-0938 mina16z Podcasta16z PodcastDevoting Your Life to Reinventing a Broken SystemAt the a16z LP Summit, we brought hundreds of our limited partners and portfolio founders together in Las Vegas.The event was truly overflowing with stories of how founders are challenging the status quo and harnessing technology to make the world a better place. Amidst these stories, it became clear that in the realms of public safety and healthcare, the stakes couldn't be higher—these sectors not only hold lives in balance but also stand as fertile ground for technological breakthroughs.In this episode, a16z General Partner Vijay Pande chats with Ed and To...2024-03-2524 minRaising HealthRaising HealthDNA as Data Storage with Vijay PandeVijay Pande, founding partner of a16z Bio + Health, dives deep with a16z Podcast host Steph Smith into the potential of DNA as a data storage mechanism.This episode, a cross-post with the a16z Podcast, draws parallels between Moore's Law and the race for "Moore's Law for DNA." Vijay discusses the density, longevity, and ubiquity of DNA, and how this could be leveraged into a data storage solution. Vijay and Steph mix technical advancements with futuristic speculation as they talk about what the future of biotech might look like. 2024-03-0521 minRaising HealthRaising HealthMetrics for a Complex Machine with Josh ClementeJosh Clemente, cofounder and president of Levels, joins Vijay Pande, founding general partner, and Daisy Wolf, investment partner at a16z Bio + Health.In this episode, engineer-turned-entrepreneur Josh charts his journey from SpaceX and Hyperloop to cofounding metabolic health-focused company Levels. With a relentless drive for data-led health monitoring, Josh highlights the potential of wearable tech for tracking various biomarkers. Josh, Vijay, and Daisy also discuss how AI can simplify complex wearables data into a comprehensible and actionable health profile, with the potential to democratize healthcare technology. 2024-02-1327 minSoftware Engineering DailySoftware Engineering DailyBiotech Special: a16z and the Biotech Revolution with Vijay PandeThere is a revolution unfolding in biotech. The confluence of new biological methods like CRISPR, virtually unlimited computational capacity, and machine learning has fundamentally transformed our ability to engineer biology for wide-ranging applications.Andreessen Horowitz, or a16z, is a venture capital firm that was founded by Marc Andreessen and Ben Horowitz.Vijay Pande is a Founding General Partner at a16z, where he leads the firm’s investments focused on the cross section of biology and computer science, including areas such as digital therapeutics, cloud biology, and computational medicine.He joins the po...2024-02-1357 mina16z Podcasta16z PodcastIntroducing Raising Health: Fireside Chat with Sean DuffyBig news from a16z: Bio Eats World, our sibling show from a16z Bio+Health, is now Raising Health!We’re excited to share Raising Health’s first episode here where Sean Duffy, cofounder and CEO of Omada Health, joins Vijay Pande, founding general partner of Bio + Health.Sean and Vijay discuss the building and growth of Omada, from the early days to now. As the cofounder of one of the original digital health companies, Sean has unique insight into the growth of both the digital health field and the changing venture capital environment. They...2024-01-1834 minRaising HealthRaising HealthPast, Present, and Future of AI with Vijay PandeBio Eats World is now Raising Health!Vijay Pande, founding partner of Bio + Health, is joined by Daphne Koller, Andrew Ng, Aviv Regev, and Jakob Uszkoreit.Vijay leads us on a reflective journey through the monumental achievements in AI from the 1980s to today, with a focus on the progress in healthcare and life sciences. This episode is drawn from the episodes we recorded in 2023 with Daphne Koller, Andrew Ng, Aviv Regev, and Jakob Uszkoreit, which are linked below.This blend of expert commentary and firsthand insights explores the burgeoning impact of AI...2024-01-0939 minRaising HealthRaising HealthFireside Chat with Sean DuffyBio Eats World is now Raising Health!On this first episode of Raising Health, Sean Duffy, cofounder and CEO of Omada Health, joins Vijay Pande, founding partner of Bio + Health.Sean and Vijay discuss the building and growth of Omada, from the early days to now. As the cofounder of one of the original digital health companies, Sean has unique insight into the growth of both the digital health field and the changing venture capital environment.  They also talk about the future of AI, how Omada is leveraging AI, and the challenges that might arise w...2024-01-0432 mina16z Podcasta16z PodcastThe Future of Longevity with Tony RobbinsWelcome to “The Ben & Marc Show”, featuring a16z’s co-founders Ben Horowitz and Marc Andreessen.  In this week’s episode, Marc and Ben are joined by special guest Tony Robbins to discuss the future of longevity.  Tony Robbins is an entrepreneur, #1 NY Times bestselling author, philanthropist, and the nation’s #1 life & business strategist.  For over four and a half decades, Tony has empowered more than 50 million people from 100 countries around the world through his audio programs, educational videos, and live seminars. He’s also the author of six international bestsellers, including “Money: Master the Game” (2014), “Unshakable: Your Financial Freedom...2023-12-261h 21The Ben & Marc ShowThe Ben & Marc ShowTony Robbins on the Future of Health & LongevityWelcome to “The Ben & Marc Show”, featuring a16z’s co-founders Ben Horowitz and Marc Andreessen.  In this week’s episode, Marc and Ben are joined by special guest Tony Robbins to discuss the future of longevity.   Tony Robbins is an entrepreneur, #1 NY Times bestselling author, philanthropist, and the nation’s #1 life & business strategist.  For over four and a half decades, Tony has empowered more than 50 million people from 100 countries around the world through his audio programs, educational videos, and live seminars. He’s also the author of six international bestsellers, including “Money: Master the Game” (2014), “Unsh...2023-12-201h 25Raising HealthRaising HealthGeneralist Medical AI with Pranav RajpurkarPranav Rajpurkar, PhD, joins Vijay Pande, founding partner of a16z Bio + Health.In this episode, Pranav and Vijay discuss a future with generalist medical AI. This is the idea of a medical AI that isn’t narrowly tailored to one specific task. As Pranav notes in the episode, the research and development process in medical AI development so far has been siloed by specialty, but generalist medical AI exists outside those siloes. If generalist medical AI is successful, it could act as a dynamic support system to a physician, almost like a medical resident. 2023-12-1230 minRaising HealthRaising HealthSupercharging Discovery with Evan FeinbergEvan Feinberg, PhD, founder and CEO at Genesis Therapeutics, joins Vijay Pande of Bio + Health.Together, they talk about how Evan’s work in the lab (ironically, Vijay's lab at Stanford!) translated to the creation of Genesis, which is tackling the problem of drug discovery through AI. They also discuss how the Genesis team is building specifically to carry on work at the intersection of ML, biotech, and chemistry. 2023-10-3129 minRaising HealthRaising HealthInterpretability and the AI "Clear Box" with Surya GanguliNote that due to technical difficulties, the audio quality of this episode may vary.Surya Ganguli, PhD, an associate professor at Stanford University and a neural dynamics researcher, joins Vijay Pande of Bio + Health.Together, Surya and Vijay chatted about the interpretability of AI and how the AI black box could someday become a "clear box." They also talk through a future of AI-augmented humans, and where humans might excel compared with AI.  2023-10-1024 mina16z Podcasta16z PodcastWhen AI and Genomics CollideToday’s episode continues our coverage from a16z’s recent AI Revolution event. You’ll hear a16z Bio & Health GP Vijay Pande speak with Daphne Koller about the fascinating convergence of machine learning and genomics – two industries that have benefitted decades of investment and progress – which are now colliding head on.Daphne is a prominent innovator at this intersection, as a long-time professor in computer science at Stanford and co-founder of Coursera, who has decided to step back into the arena with her company Insitro. In fact, Insitro is a blend of in silico and in virto!2023-10-0324 minRaising HealthRaising HealthWhen Quantity Becomes Quality with Aviv RegevToday's episode features Aviv Regev, PhD, the Head and Executive VP of Genentech Research and Early Development, and founding co-chair of the Human Cell Atlas. She is joined by Vijay Pande of Bio + Health.Together, Aviv and Vijay talk about how Aviv's love of both abstractions and details led her to biology, how CRISPR really set the field into motion, and how AI could transform the process of biological and medical discovery. 2023-09-2629 minRaising HealthRaising HealthNavigating the Future of AI with Andrew NgAndrew Ng, PhD, a distinguished authority in the field of AI, is known for founding DeepLearning.AI and multiple other ventures. He also co-founded and led Google Brain and serves as an Adjunct Professor in Stanford University's Computer Science Department. In this episode, he is joined by Vijay Pande, founding partner of a16z Bio + Health.Andrew has thought deeply about the implications of integrating AI into many areas of our lives, going so far as to put out a public social media call for people who believe AI is dangerous to speak with him. He and...2023-09-1931 minThe Times Tech PodcastThe Times Tech PodcastAndreessen Horowitz's Vijay Pande: "AI doctors" The Sunday Times’ tech correspondent Danny Fortson brings on Vijay Pande, head of Andreessen Horowitz’s $1.5bn bio fund, to talk about how artificial intelligence is impacting healthcare (3:30), tools that “understand” biology (8:50), trying to eliminate cancer (12:50), trying to get techie founders to get into healthcare (14:25), America’s plunging life expectancy (18:00), the (potential) end of radiology (21:10), AI’s “hallucination" problem in healthcare (25:55), the future of therapy (29:00), putting healthcare on the Moore’s Law curve (33:10), using automation to slash the industry’s costs and inefficiencies (37:30), the next trillion dollar company (40:00), if capitalism is the best way to crack healthcare (45:40), and solving the billing proble...2023-04-2851 mina16z Podcasta16z Podcast2023 Big Ideas in Technology (Part 2)At the end of 2022, our team at a16z asked dozens of partners across the firm to spotlight one big idea that startups in their fields could tackle in 2023.Emerging from this exercise came 40+ builder-worthy pursuits for the year, ranging from entertainment franchise games to precision delivery of medicine to small modular reactors, and of course loads of AI applications.In our 2-part series, we’ll be covering 12 of these big ideas with the partners that shared them.Here in part 2, we’ll cover Fintech, American Dynamism, and Bio & Health. Listen in as we c...2023-01-271h 08Raising HealthRaising HealthAI is Here. Now What?AI is here...so why isn't it in every clinic? Eric Topol talks with a16z Bio + Health general partners Vijay Pande and Vineeta Agarwala and editorial lead Olivia Webb about what's taking so long, where AI can help patients and providers the most, what needs to happen to speed up adoption, and whether data or policy is more likely to be an obstacle. Eric has written extensively about AI in healthcare, including in his most recent book Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. He also writes a Substack focused on Co...2022-12-0134 minBIOSBIOS24. Tech Eats Bio: Vijay Pande - General Partner @ Andreessen Horowitz (a16z) Bio FundVijay Pande is a General Partner @ Andreessen Horowitz (a16z), where he focuses on investments in Biopharma & Healthcare. As the founding investor of a16z’s Bio Fund, Vijay leads the firm’s investments at the cross section of biology and computer science, including applications in computation, machine learning, and artificial intelligence in healthcare; digital therapeutics; diagnostics; and other novel transformative scientific advances applied to industry that take bio beyond healthcare. Op-eds by Vijay defining trends and issues in this emerging space have been published by The New York Times, Scientific American, and Forbes, among others. He is a...2021-08-1743 mina16z Livea16z Livea16z Bio + Health #16: Digital Health for Complex CareIn what ways is digital health for complex care under or overrated? [4:04]Are digital health solutions better suited to tackling clinical or non-clinical needs for complex care? [17:32]The challenge of the physician's inbox [27:55]Have we meaningfully moved the needle on complex digital care? If so, where? [32:08]Should we focus on applying basic tech to easy optimization and automation problems or advanced tech to more complex problems? [41:48] It's Time to Heal, Mondays at 5pm PT on Clubhouse. Join the a16z bio team — Jorge Conde, Vineeta Agarwala, Julie Yoo, and Vijay Pande — plus special guests as they explore all the ways...2021-06-181h 09a16z Livea16z Livea16z Bio + Health #15: The mRNA Revolution with Moderna CEO Stephane BancelmRNA research before COVID and how "mRNA is code" [3:21]The early days of COVID: designing a vaccine in 48 hours [5:44]The software behind the vaccine: getting mRNA researchers out of Excel and into a drug design studio [9:11]The first draft of the vaccine was the final draft [11:10]How the government sped up vaccine development for COVID [12:18]What other new vaccines will come from mRNA?  [15:34]How far are we from these mRNA vaccines? What do we need for them to be widely available? [25:31]Open sourcing Moderna  [27:53]When will COVID vaccines be available for a five year old? [29:47]The three factors that matter wh...2021-06-111h 07POD OF JAKEPOD OF JAKE#64 - VIJAY PANDEVijay is a general partner at Andreessen Horowitz, where he focuses on investments in biopharma and healthcare. As the founding investor of a16z’s Bio Fund, he leads the firm’s investments at the cross section of biology and computer science. Previously, Vijay was the Henry Dreyfus Professor of Chemistry and Professor of Structural Biology and of Computer Science at Stanford University. During his time at Stanford, Vijay co-founded Globavir Biosciences and the Folding@Home Distributed Computing Project for disease research. Vijay remains an Adjunct Professor of Bioengineering at Stanford University and holds a BA in Physics from Prince...2021-05-2756 minRaising HealthRaising HealthWorld’s largest supercomputer v. biology’s toughest problemsThis episode was recorded in March of 2019 to celebrate the 20th anniversary of Folding at Home, the distributed computing project for simulating protein dynamics, and originally aired on The a16z Podcast. Folding at Home is run on millions of devices, is the world’s largest supercomputer, and tackles some of biology’s toughest problems, including COVID-19.Proteins are molecular machines that must first assemble themselves to function. But how does a protein, which is produced as a linear string of amino acids, assume the complex three-dimensional structure needed to carry out its job? That's where...2021-05-2533 mina16z Livea16z Livea16z Bio + Health #14: How do we safely deliver more gene therapies?What inspired Eric and Sam to start Dyno [4:09]How does the use of ML impact Dyno's GTM [10:40]The current challenges of gene therapy [21:43]Why Dyno wants to be a horizontal platform for gene therapy [30:56]How does Dyno think about competition [44:23]After party and audience Q&A [52:01]It's Time to Heal, Mondays at 5pm PT on Clubhouse. Join the a16z bio team — Jorge Conde, Vineeta Argawala, Julie Yoo, and Vijay Pande — plus special guests every week as they explore all the ways that biology is technology. 2021-05-181h 14Raising HealthRaising HealthThe New Science of Cell ShapeThey say you should never judge a book by its cover, but can you judge a cell by its shape? On this episode, host Lauren Richardson is joined by Maddison Masaeli (CEO and cofounder of Deepcell), and a16z general partner Vijay Pande (whose lab at Stanford focused on the development of novel computational methods for simulating biology), to discuss what we can learn by characterizing a  cell's shape — also known as its morphology. We've long appreciated that morphology can be used to discriminate cells, for example, cancer cells look very different than the surrounding tissue and can be spo...2021-05-1132 mina16z Livea16z Livea16z Bio + Health #13: Care After COVID with Shantanu NundyOn this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, Vijay Pande, and Jorge Conde talk to guest Shantanu Nundy, the Chief Medical Officer of Accolade. The conversation covers Dr. Nundy's new book, "Care After Covid: What the Pandemic Revealed Is Broken in Healthcare and How to Reinvent It",  the next steps in the evolution of hospitals, interoperability (or lack thereof), and more. 2021-05-1159 mina16z Livea16z Livea16z Bio + Health #9: Engineering CRISPR with Ben OakesOn this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala and Vijay Pande talk to guest Ben Oakes, cofounder, President and CEO of Scribe Therapeutics. The conversation covers the the power of engineering gene editors, the transition from academia to a startup, and how to select the first indication to target with a novel bio platform.2021-04-0843 minRandom WalksRandom WalksForging revolutionary technologies and espousing an equitable future with Bharath Ramsundar (Stanford)In this episode, I converse with Bharath Ramsundar, the creator of The DeepChem Project. Bharath received a BA and BS from UC Berkeley in EECS and Mathematics and was valedictorian of his graduating class in mathematics. He went on to finish a PhD in computer science at Stanford University where he studied the application of deep-learning to problems in drug-discovery, and was sponsored by the very prestigious Hertz Fellowship and advised by Prof. Vijay Pande. After his PhD, Bharath co-founded Computable, a startup that built better tools for collaborative dataset management.At Stanford Bharath created The DeepChem...2021-04-031h 27a16z Livea16z Livea16z Bio + Health #8: How to Innovate within Biopharma with Jay BradnerOn this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande talk to guest Jay Bradner, President of the Novartis Institute of Biomedical Research (NIBR). The conversation covers the challenges of translating basic research into a clinical application, the state of innovation in therapeutics, and the transition from drug hunting to drug farming.2021-04-0145 mina16z Livea16z Livea16z Bio + Health #7: The Power of Patient Data with Anne WojcickiOn this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande, along with a16z cofounder Marc Andreessen, talk to guest Anne Wojcicki, CEO of 23andme. The conversation covers the shifting trends and perceptions at the intersection of bio and tech, the power of patient data and importance of giving people access to their own health data, and advice to founders on when to lead and when to listen.2021-03-3037 mina16z Livea16z Livea16z Bio + Health #6: AI for Biologics With Mark DePristo and Peyton GreensideOn this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande talk to guests Peyton Greenside and Mark DePristo of BigHat Biosciences. The conversation covers the growing role of artificial intelligence and machine learning in drug development and specifically in biologics and protein therapeutics.2021-03-1851 mina16z Livea16z Livea16z Bio + Health #5: From COVID to Consumerism & the Future of Virtual First Care with Stephen KlaskoOn this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Julie Yoo, Vineeta Agarwala, Jorge Conde, and Vijay Pande, along with market development partner Venkat Mocherla, talk to guest Dr. Stephen Klasko, the president of Thomas Jefferson University and CEO of Jefferson Health about transforming the US healthcare system.2021-03-1347 minRaising HealthRaising HealthThe Theory of a Thousand BrainsIn this episode, we talk with Jeff Hawkins—an entrepreneur and scientist, known for inventing some of the earliest handheld computers, the Palm and the Treo, who then turned his career to neuroscience and founded the Redwood Center for Theoretical Neuroscience in 2002 and Numenta in 2005—about a new theory about how the cells in our brain work to create intelligence. What exactly is happening in the neocortex as our brains process and interpret information and sensory input—like sight, smell, touch, or language, or math—to create a perception of and to navigate through the world around us?  2021-03-1239 mina16z Livea16z Livea16z Bio + Health #4: The History and Future of Genome Engineering with George ChurchOn this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande, along with a16z cofounder Marc Andreessen, talk to guest Dr. George Church of Harvard University about past, future, and power of genome engineering.2021-03-1042 mina16z Livea16z Livea16z Bio + Health #3: Metabolic Health with Casey MeansOn this episode of the new a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Jeff Jordan, and Vijay Pande, talk to guest Dr. Casey Means, co-founder of Levels Health, about metabolism and metabolic health.2021-03-0956 minRaising HealthRaising HealthThe Art and Science of Biology's FutureIn this episode of Bio Eats World, we talk to Dr. Jennifer Doudna—winner of the 2020 Nobel Prize for the co-discovery (with Emmanuelle Charpentier) of CRISPR-Cas9—about the art and science of biology. Huge breakthroughs such as Doudna's—which began with the identification of CRISPR in bacteria and was then built into a highly adaptable genome editing platform—are now fueling the evolution of the field. Fundamental knowledge that has largely come from curiosity-driven science has converged with enabling technologies, allowing scientists and biologists in particular to do things that even a couple of years ago, we would have found unimagin...2021-02-2629 mina16z Livea16z Livea16z Bio + Health #2: Digital Diagnostics with Gaurav SingalOn this episode of the new a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Vijay Pande, talk to guest Dr. Gaurav Singal about the future of digital diagnostics: what are they, who stands to benefit from them, and critically, who pays.2021-02-2642 minThe AI Health PodcastThe AI Health Podcasta16z's Dr. Vijay Pande on Innovation in Medical AIDr. Vijay Pande is a general partner at Andreessen Horowitz and an Adjunct Professor of Bioengineering at Stanford University. As the founding investor of a16z’s Bio Fund, he leads the firm’s investments at the cross section of biology and computer science. He speaks with us about drug discovery and other major opportunities for entrepreneurs in the medical AI space. Pranav and Adriel first talk about the protein folding problem and the Folding@Home Distributed Computing Project, and then provide context for the interview, which starts at 6:44. If you like what you hear, let a frie...2021-02-2550 minRaising HealthRaising HealthValue Versus Volume (in Healthcare)The way we pay for healthcare in the US has long been by fee-for-service: per doctor visit, per test, per surgery, per hospital stay. But that system has led to rapidly escalating volumes of services and cost to the system—without actually improving outcomes. What if we shifted everything towards paying for value—and outcomes—instead? In this episode, Todd Park, co-founder and executive chairman of Devoted Health, and formerly Chief Technology Officer and technology advisor for President Barack Obama; a16z General Partner Vijay Pande; and Bio Eats World host Hanne Winarsky—talk all about the megatrend of value-based care, an...2021-02-2037 minRaising HealthRaising HealthThings That Make You Go Hmmmm in HealthcareIn this episode, we share an episode of the brand new a16z Live podcast feed called “It’s Time to Heal”—a live conversation on audio/drop in chat app Clubhouse every Monday at 5pm PT, covering the latest trends and future of bio and healthcare with special guests and entrepreneurs, hosted by a16z bio partners Vineeta Agarwala, Jorge Conde, Vijay Pande, and Julie Yoo. Last week, a16z Bio General Partners and a16z cofounder Marc Andreessen talked with guest Nihkil Krishnan, comedian and author known for his Out-of-Pocket Substack newsletter and Slack community for healthcare builders, award wi...2021-02-1759 mina16z Livea16z Livea16z Bio + Health #1: Things That Make You Go Hmmmm in Healthcare with Nikhil KrishnanThe first episode of the new a16z Bio Clubhouse Show "It's Time to Heal" on a16z Live. a16z General Partners Vineeta Agarwala, Jorge Conde, Vijay Pande, Julie Yoo, and a16z cofounder Marc Andreessen talk to guest Nihkil Krishnan about healthcare—the stuff we're all thinking but don't talk about.2021-02-1657 mina16z Podcasta16z PodcastBaumol's Cost Disease, in Healthcare... and Where We Go NextIf software’s eating the world -- and more specifically, bringing costs down and increasing productivity through entire industries -- why have some industries, like healthcare, been so resistant? And what could the future look like once technology really gets in? With a16z co-founder -- and author of the now nearly decade-old thesis of “software eating the world” -- Marc Andreessen, in conversation with a16z bio general partner Vijay Pande. This episode originally ran on our show Bio Eats World, but we’re sharing it here in the new year as it’s very relevant for ANYone...2021-01-0630 minRaising HealthRaising HealthThe Cost Disease in Healthcarewith @pmarca and @vijaypande How come things like healthcare, education, and housing get more and more expensive, but things like socks, shoes, and electronics all get cheaper and cheaper? In this episode of Bio Eats World, a16z founder and internet pioneer Marc Andreessen, and General Partner Vijay Pande, discuss the lesser known law of economics that explains why healthcare, education and housing is so damn expensive, and getting worse. What’s really at heart is tech’s ability to transform (expensive) services into (affordable) goods: think of the cost of a live string quartet, versus a streamed recorded track; or t...2020-12-1429 min16 Minutes News by a16z16 Minutes News by a16zAlphaFold! Protein Folding, Beyond the HypeIn this episode of our show 16 Minutes -- where we talk about the headlines, and where we are on the long arc of tech trends -- we cover the news around Google DeepMind's AlphaFold system for predicting the 3-D structure of proteins outperforming 100 teams across 20 countries in the 14th Community Wide Assessment on the CASP (Critical Assessment of Structure Prediction) challenge. The challenge, which takes place every other year (over several months) tracks progress, key metrics, and state-of-the-art on predictive techniques for protein folding.This isn’t just an academic challenge; it matters because proteins define and po...2020-12-0727 minRaising HealthRaising HealthBiology by DesignWe’re at the dawn of a new era where we’re truly able to design biology: from genetically engineered cotton, to meat made from plants, to incredibly complex new therapies composed of engineered cells and genes. And that's just the very beginning. One day, just about everything will be genetically engineered, from our medicines to our materials and manufacturing and much more. The question is no longer, can we design biology? Instead the question now is, what can we build with these tools? So how does that really happen? How can we build precise functions and circuits inside cells? How...2020-10-1332 min16 Minutes News by a16z16 Minutes News by a16zA Nobel for CRISPR! When, Who, How, What Now"It's CRISPR!" This week, the Nobel Prize in Chemistry was awarded to scientists Emmanuelle Charpentier and Jennifer Doudna (also an a16z co-founder, of Scribe Therapeutics), for the development of the CRISPR/Cas9 method for genome editing -- a technology that's "had a revolutionary impact on the life sciences, is contributing to new cancer therapies, and may make the dream of curing inherited diseases come true".While many describe this technology as "genetic scissors", one of the sharpest tools, is that analogy too limited for describing the true power and potential of CRISPR as a gene-editing platform...2020-10-1023 mina16z Podcasta16z PodcastThe Biology of Aging: Introducing Bio Eats World (ep 1)Welcome to the first episode of Bio Eats World, a brand new podcast all about how biology is technology. Bio is breaking out of the lab and clinic and into our daily lives -- on the verge of revolutionizing our world in ways we are only just beginning to imagine.In this episode, we talk all about the science of aging. Once a fringe field, aging research is now entering a new phase with the first clinical trials of aging-related drugs. As the entire field shifts into this moment of translation, what have we learned? What are...2020-09-2328 minWhen Science SpeaksWhen Science SpeaksFrom Science Writer to Venture Capitalist and Biotech Startup Advisor with Steve Dickman  On this week's episode, Mark's guest is Steve Dickman, CEO of CBT Advisors, a strategic consultancy supporting the biotech industry.  Topics discussed during the episode include: How Steve made the transition from working at Science and at  Nature - where he founded and ran the first Nature news bureau in Germany, among other responsibilities - to thriving in the ecosystem of VCs, Private Equity, and startups The obstacles Steve faced as he shifted his professional focus and how he overcame them How Steve develops and delivers persuasive, impactful stories for his clients, with examples fro...2020-09-221h 04Raising HealthRaising HealthThe Biology of Agingwith @LauraDeming, @kpfortney, @vijaypande, and @omnivorousread Welcome to the first episode of Bio Eats World, a brand new podcast all about how biology is technology. Bio is breaking out of the lab and clinic and into our daily lives—on the verge of revolutionizing our world in ways we are only just beginning to imagine. In this episode, we talk all about the science of aging. Once a fringe field, aging research is now entering a new phase with the first clinical trials of aging-related drugs. As the entire field shifts into this moment of translation, what have we learned? Wh...2020-09-2226 min16 Minutes News by a16z16 Minutes News by a16zApple and the 'Doctor’s Office on a Wrist'We cover the latest coming out of Apple's event yesterday, focusing on their new watches (including a lower price model); new sensors (including blood oxygen); and services for healthcare. Is always-on, (relatively) low-cost, passive monitoring for fitness and mainstream consumers really, finally the wedge into data for clinical applications as well? What features -- cost, efficacy, battery power, convenience, data, business model -- do and don't matter when it comes to filling in the gaps between the doctor's office and our mobile selves, families, home care?We take an, ahem, "pulse check" on where we are when...2020-09-1719 min16 Minutes News by a16z16 Minutes News by a16zTeladoc & Livongo, Is Virtual Care Fully Here?In this episode of 16 Minutes -- our show where we cover recent headlines; tease apart what's hype/ what's real; and help orient where we are, trends-wise, on the long arc of innovation -- we cover the merger of Teladoc and Livongo, which was announced just a few days ago. The $18.5B deal is a big deal not just because of the dollars and validation in public markets, but because it's aimed at creating "the first true health tech giant", and an end-to-end digital health platform at scale. However, the scale and opportunity in healthcare is so massive -- this i...2020-08-1023 mina16z Podcasta16z PodcastWhy We Shouldn’t Fear AI in Healthcare"Why We Shouldn’t Fear the ‘Black Box’ of AI (in Healthcare and Everywhere)" by Vijay Pande. First published in the New York Times, January 2018. You can also find and share this article at a16z.com/aidoctor 2020-07-0706 mina16z Podcasta16z PodcastRead-Alouds, ContinuedToday we're continuing a series we started a while ago of read-alouds (for more context on the why and why now check out episode #500 on how we podcast!).The first was episode #544 in April, It's Time to Build, read out loud by Marc Andreessen; what follows are  three more pieces read out loud by their authors:"Why Every Company Will Become a Fintech Company: The Next Era of Financial Services and the 'AWS Phase' for Fintech" by Angela Strange"When One App Rules Them All: The Case of WeChat and Mobile in China" by Connie Chan, f...2020-07-0700 min16 Minutes News by a16z16 Minutes News by a16zVideogames as Medicines -- So What Is/Isn't a Digital Drug?The FDA just approved the first ever videogame that can now be legally marketed and prescribed as a medicine. It's a game called EndeavorRX (formerly known as Project EVO and developed by Akili Interactive based on technology licensed from a neuroscience lab at the University of California San Francisco) -- and is for 8-12 year olds with Attention Deficit Hyperactivity Disorder or ADHD.So where does this fit in the broader category of "digital therapeutics", which have proven to be effective as therapeutics as in the case of the Diabetes Prevention Program administered by Omada Health (which...2020-06-2119 minAzeem Azhar\'s Exponential ViewAzeem Azhar's Exponential ViewEngineering Biology: The Next FrontierThe increasing capabilities of computing have changed biology from a realm dominated by scientific discovery to one that intersects with engineering and innovation. Vijay Pande, a General Partner at Andreessen Horowitz, joins Azeem Azhar to discuss the emergence of this novel industry at the interface of technology and biology. They also discuss: The most promising technologies to combat Covid-19 that are being tested. Why next-gen biotech companies look increasingly like tech startups. Why our long-term health depends on regulators and society engaging with this tech. Further reading: “The Next Trillion Dollar Market” (Exponential View podc...2020-06-1738 mina16z Podcasta16z PodcastWorld’s Largest Supercomputer v. Biology’s Toughest ProblemsProteins are molecular machines that must first assemble themselves to function. But how does a protein, which is produced as a linear string of amino acids, assume the complex three-dimensional structure needed to carry out its job? That's where Folding at Home comes in. Folding at Home is a sophisticated computer program that simulates the way atoms push and pull on each other, applied to the problem of protein dynamics, aka "folding". These simulations help researchers understand protein function and to design drugs and antibodies to target them. Folding at Home is currently studying key proteins from t...2020-06-1432 mina16z Podcasta16z PodcastJournal Club: Using CRISPR to Prevent Coronavirus and Influenza InfectionIn this episode of a16z bio Journal Club, general partner Vijay Pande, bio deal team partner Andy Tran, and bio editor Lauren Richardson discuss a novel CRISPR-Cas-based anti-viral strategy.The discussion covers the differences between this newly developed prophylactic strategy, traditional vaccines, and anti-viral drugs; how this strategy can be engineered to target a huge range of coronavirus and influenza strains; and the next steps needed to go from paper to practice:“Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza” in Cell (April 2020), by Timothy Abbott, Girija Dhamdhere, Yanxia Liu, Xueqiu Lin, L...2020-05-1517 min16 Minutes News by a16z16 Minutes News by a16zDrugs & Debates: Real World Data, Randomized Controlled TrialsIf the best way to know whether a medicine is effective is through a clinical trial, then where does (and doesn't) real-world data and real-world evidence come in? The topic is always top of mind in drug development, with additional focus as of 2016 thanks to the 21st Century Cures Act -- but is especially heated lately given recent concerns and claims around particular drugs in the context of the novel coronavirus pandemic.So in this short-but-deep dive episode of 16 Minutes on the News, a16z general partner in bio Vijay Pande -- previously a professor of Chemistry, S...2020-03-2917 min16 Minutes News by a16z16 Minutes News by a16zDirect Listings NYSE SEC; Vaping Apps & Apple, CBD & FDA (#16)This is the 16th episode of 16 Minutes, our news show where we cover the top headlines, the a16z Podcast way: what’s real / what’s hype; why they matter from our vantage point in tech.This week, we cover the following news (in conversation with Sonal Chokshi):NYSE & SEC back and forth over direct listings -- The NYSE recently proposed allowing companies to raise capital during direct listings (currently, they're different than IPOs in that there is no offering); the SEC rejected it; and they just filed a new proposal... but beyond this news and thes...2019-12-1615 minGreat InterviewsGreat Interviewsa16z Podcast: AI and Your Doctor, Today and Tomorrow Podcast: a16z Podcast (LS 62 · TOP 0.1% what is this?)Episode: a16z Podcast: AI and Your Doctor, Today and TomorrowPub date: 2019-06-13Get Podcast Transcript →powered by Listen411 - fast audio-to-text and summarizationwith Eric Topol (@EricTopol) and Vijay Pande (@vijaypande) Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol, cardiologist and chair of innovative medicine at Scripps Research, and a16z’s general partner on the Bio Fund Vijay Pande, have a conversation around Topol’s new book, Deep Medicine...2019-12-0344 min16 Minutes News by a16z16 Minutes News by a16zPharma Drones; Veteran Health Records; Light to Voice Hacks (#14)This is the 14th episode of 16 Minutes, our weekly-ish news show where we quickly cover the top headlines of the week, the a16z Podcast way: what’s real, what’s hype from our vantage point in tech. This week, we cover the following news -- with a16z experts general partner Julie Yoo and market dev partner Venkat Mocherla from the bio team, and former CSO/ a16z security operating partner Joel de la Garza -- in conversation with Sonal Chokshi:UPS drones deliver prescriptions -- For the first time ever, drones delivered prescription medication directly to resi...2019-11-1519 min16 Minutes News by a16z16 Minutes News by a16zAmazon Healthcare, Oculus & VR/AR, Google Quantum Supremacy? (#10)Our news podcast, 16 Minutes -- where we quickly cover the top headlines of the week, the a16z way (why are these topics in the news; what's real, what's hype from our vantage point of tech trends) -- is now only available as its own show feed, separately from the main a16z Podcast... so be sure to subscribe wherever you get your podcasts if you want our weekly news & tech take!This is the tenth episode of the show, and this week we cover a variety of topics with the following a16z experts:Amazon...2019-09-3022 min16 Minutes News by a16z16 Minutes News by a16zApple Camera, Services; Wearables - Where are We (#8)This is episode #8 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends.This week we cover, with the following a16z experts:Apple's latest event announcing new products and services across mobile, TV, and gaming; where is (and isn't) innovation happening, and what's next -- with a16z's Benedict Evans;wearables and health trackers such as Fitbit supplying services to the government of...2019-09-1620 min16 Minutes News by a16z16 Minutes News by a16zThe Opioid Crisis (#4)This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we do a short but deep dive on the opioid crisis, given recent data around where and who was behind the manufacturing and distribution of specific opioids: How do opioids work, why these drugs? Who's to blame? What are other directions for managing pain -- and where...2019-08-0418 min16 Minutes News by a16z16 Minutes News by a16zNeuralink & Brain Interfaces, TikTok, FaceApp, iHeartRadio (#1)Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z podcast way — why are these topics in the news; what’s real, what’s hype from our vantage point; and what are our experts’ quick takes on these trends? This is the first episode of the show, and this week we cover the below topics with the following experts: Neuralink’s recent news/ event/ whitepaper and the trend of brain-computer interfaces -- with a16z bio general partner Vijay Pande TikTok video influencers and AI-driven media and...2019-07-2120 mina16z Podcasta16z Podcasta16z Podcast: AI and Your Doctor, Today and Tomorrowwith Eric Topol (@EricTopol) and Vijay Pande (@vijaypande) Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol, cardiologist and chair of innovative medicine at Scripps Research, and a16z’s general partner on the Bio Fund Vijay Pande, have a conversation around Topol’s new book, Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. What is the impact AI will have on how your doctor engages with you? On the nature of the doctor's visit as a whole? How will AI impact not just doctor-patient interactions, but diagnosis, prevention, predic...2019-06-1444 mina16z Podcasta16z Podcasta16z Podcast: Deep Learning for the Life Scienceswith Vijay Pande (@vijaypande) and Bharath Ramsundar Deep learning has arrived in the life sciences: every week, it seems, a new published study comes out... with code on top. In this episode, a16z General Partner Vijay Pande and Bharath Ramsundar talk about how AI/ML is unlocking the field in a new way, in a conversation around their book, Deep Learning for the Life Sciences: Applying Deep Learning to Genomics, Microscopy, Drug Discovery, and More (also co-authored with Peter Eastman and Patrick Walters. So -- why now? ML is old, bio is certainly old...2019-06-0731 minNL HaftaNL HaftaHafta 217: Modi's interview with Arnab, Mission Shakti, NYAY and moreIn this week’s episode, host Abhinandan Sekhri is joined by Madhu Trehan, Raman Kirpal, Manisha Pande, and lawyer Gautam Bhatia.The podcast kicks off with Gautam talking about his latest book, The Transformative Constitution: A Radical Biography in Nine Acts. It draws on pre-Independence legal and political history and is an analysis of the oppressive forces apart from the State. In his book, he argues that the Constitution was intended to transform not only the political identity of Indians but also the social relationships on which legal and political structures rest.Abhinandan proceeds with a comparative interpretation of the at...2019-04-0800 minNL HaftaNL HaftaChhota Hafta — Episode 217In this week’s episode, host Abhinandan Sekhri is joined by Madhu Trehan, Raman Kirpal, Manisha Pande, and lawyer Gautam Bhatia. The podcast kicks off with Gautam talking about his latest book, The Transformative Constitution: A Radical Biography in Nine Acts.The discussion moves to Arnab Goswami's interview with Prime Minister Narendra Modi. Discussing Mission Shakti, Madhu describes what she calls the “remarkable discomfiture” with which Modi made his announcement. The conversation also covers Rahul Gandhi's announcement of the NYAY scheme, Vijay Mallya recent statements after the Jet Airways bailout, cessation dialogues in Kashmir and Sikkim, and a whole lot more.2019-03-3000 mina16z Podcasta16z Podcasta16z Podcast: Incenting Innovation Inside, Loonshots to Moonshotswith Safi Bahcall (@safibahcall), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) A "moonshot" is a destination (like going to the moon, quite literally) -- but nurturing "loonshots" (which often involves a number of stumbles along the way) is how we get there. This goes beyond the trite mantra of failing fast! It is about not having "false fails" or not killing the seemingly small ideas that could lead to outsized yet unexpected outcomes, observes Safi Bahcall (physicist, ex-startup founder, and CEO of a public biotech company), author of the new book, Loonshots: How to Nurture the Crazy I...2019-03-2547 minNL HaftaNL HaftaNL Session With Sena - Episode 04Have you read the latest NL Sena story, The Cauvery Chronicles II: Ponni’s Perish? If not, do it. In this podcast, Manisha Pande, Anish Daolagupu and NL subscriber Rahul Pandey discuss different facets of this report with its author TR Vivek.TR Vivek answers the questions posed by contributors to the story and asks Rahul what made him pay for the story.The story was made possible thanks to Rahul Pandey, Gayatri Natrajan, Vijay Krishnan, and other members of the NL Sena. We want to do more such stories and you can help. Be a part of the NL Sen...2019-03-0600 mina16z Podcasta16z Podcasta16z Podcast: Dark Data in Healthcarewith Susannah Fox (@susannahfox), Anil Sethi (@anilsethiusa / @ciitizencorp), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) The problem of "dark data" in healthcare isn't just a feel-good empowerment thing, but a structural issue that leads to miscommunication and extra friction, different players in the entire healthcare system not being able to collaborate with each other, and just major missed opportunities all round. And yes, it also leads to lack of empowerment for patients, not to mention doctors too (who often have less than 30 minutes on site to do their jobs). But we already know all that...2019-01-1636 mina16z Podcasta16z Podcasta16z Podcast: The Science and Business of Innovative Medicineswith Vas Narasimhan (@vasnarasimhan), Jorge Conde (@jorgecondebio), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)On average, only 1 out of 20 medicines works when we actually bring them into the human body, and these rates of success haven't moved much in the pharma industry overall in the past 15 years, despite much scientific progress. Because if you really think about it, it's incredible that we find any human medicine that works at all, given that human beings are the product of billions of years of evolution, and represent an incredibly complex system we do not fully understand. Yet the business...2019-01-1459 mina16z Podcasta16z Podcasta16z Podcast: All About Synthetic Biologywith James J. Collins, Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread) The idea of 'designing biology' -- once science fiction -- has over the last 20 years become just... science. In this episode, a16z bio general partner Vijay Pande with Hanne Tidnam talk all about the field of synthetic biology with James J. Collins, professor of bioengineering at MIT. Collins, whose work in synthetic biology and systems biology pioneered the field, has also launched a number of companies and received numerous awards and honors (including a MacArthur "Genius" Award, an NIH Director's Pioneer Award, and Sanofi-Institut Pasteur Aw...2019-01-1135 minNL HaftaNL HaftaHafta 189: Vijay Mallya, Serena Williams, Kerala nun’s rape case & moreOn this week’s episode, we have Aarti Tikoo Singh, senior assistant editor at The Times of India, joining Abhinandan Sekhri, Madhu Trehan and Manisha Pande. Abhinandan kicks off the podcast with a discussion about Kashmiri Pandits, and their association with Kashmir. The conversation then moves to Vijay Mallya, and his recent claims of an alleged meeting with the Finance Minister, Arun Jaitley. The panel talks about the credibility of his claims, and implications of such a meeting. Manisha then brings up The Indian Express’ interview with Maoist leader Pahad Singh, and Madhu asks what a journalist must keep in mind...2018-10-1200 minNL HaftaNL HaftaChhota Hafta – Episode 189NL Hafta has gone behind the paywall, but we love our listeners. So, here's a little sneak peek into the complete episode.In this episode, Aarti Tikoo Singh, senior assistant editor of The Times of India, joins the regular Hafta gang of Abhinandan Sekhri, Madhu Trehan and Manisha Pande. They discuss Vijay Mallya and Finance Minister Arun Jaitley’s alleged meeting, Kerala nun’s rape case, Serena Williams’ standoff with the umpire and more. Listen up!Listen to the full episode here: https://www.newslaundry.com/2018/09/14/hafta-189-vijay-mallya-serena-williams-kerala-nuns-rape-case-more See acast.com/privacy for privacy and opt-out information.2018-09-1400 mina16z Podcasta16z Podcasta16z Podcast: Breaking Into Biowith Atul Butte (@atulbutte), Daphne Koller (@daphnekoller), and Vijay Pande (@vijaypande) Whether you’re an academic seeking to move out of research and into industry, or simply interested in working at a bio startup, this episode of the a16z Podcast is for you. It covers everything from how to build a brand in the space when you don’t have one to how the bio and how the healthcare startup ecosystem is different from traditional tech (or traditional pharma), to how to choose the right co-founder -- or even identify what problems to solve and build a co...2018-05-0241 mina16z Podcasta16z Podcasta16z Podcast: Putting AI in Medicine, in Practicewith Brandon Ballinger (@bballinger), Mintu Turakhia (@leftbundle), Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread) There’s been a lot of talk about technology -- and AI, deep learning, and machine learning specifically -- finally reaching the healthcare sector. But AI in medicine isn’t actually new; it’s actually been there since the 1960s. And yet we didn’t see it effect a true change, or even become a real part our doctor’s offices -- let alone routine healthcare services. So: what's different now? And what does AI in medicine look like, practically speaking, whether it's ensuring t...2017-11-0329 mina16z Podcasta16z Podcasta16z Podcast: Mindsets for Engineering BiologyHead of the largest bioengineering lab in the world, former chairman of the FDA and one of the few recipients of the National Medals of Science and of Technology and Innovation, Bob Langer's work has spanned multiple fields and settings and has been applied across numerous fields, from pharmaceutical to chemical, biotechnology to medical device companies. What does it mean to move across disciplines like this, from science to engineering, both in the lab and into the field? In this conversation with general partner and head of the a16z bio fund Vijay Pande (with Hanne Tidnam), Lang...2017-10-0628 minBusiness and PhilosophyBusiness and PhilosophyQuantum Computing with Vijay Pande Quantum computing is based on the system of quantum mechanics. In quantum computing, we perform operations over qubits instead of bits. A qubit is a vector, which can take on many more values than 0 or 1. The technology used to implement quantum computers is advancing such that it has its own Moore’s Law, but it can also leverage the classical advancements of Moore’s Law. If classical computing advances at the exponential pace of 2^n, quantum computing advances at the pace of 2^2^n. Quantum computing will advance technology in ways that will take us b...2017-08-0349 minGreatest Hits Archives - Software Engineering DailyGreatest Hits Archives - Software Engineering DailyQuantum Computing with Vijay Pande Quantum computing is based on the system of quantum mechanics. In quantum computing, we perform operations over qubits instead of bits. A qubit is a vector, which can take on many more values than 0 or 1. The technology used to implement quantum computers is advancing such that it has its own Moore’s Law, but it can also leverage the classical advancements of Moore’s Law. If classical computing advances at the exponential pace of 2^n, quantum computing advances at the pace of 2^2^n. Quantum computing will advance technology in ways that will take us b...2017-08-0349 mina16z Podcasta16z Podcasta16z Podcast: The Cloud Atlas to Real Quantum ComputingA funny thing happened on the way to quantum computing: Unlike other major shifts in classic computing before it, it begins -- not ends -- with The Cloud. That's because quantum computers today are more like "physics experiments in a can" that most companies can't use yet -- unless you use software, not just as cloud infrastructure for accessing this computing power commercially but for also building the killer app on top of it. What will that killer app be? With quantum virtual machines and special languages for connecting and trading off classic and quantum computing, companies and developers...2017-06-3025 minNL HaftaNL HaftaHafta 116: Babri Masjid demolition, Kashmir and AmbedkarOne of this week’s most significant stories was pertaining to the Babri Masjid demolition case. LK Advani, Murli Manohar Joshi and Uma Bharti will now be tried for criminal conspiracy and the Hafta team discusses what bearings this would have on the BJP and 2019 General Elections. Paranjoy Guha Thakurta, editor of Economic and Political Weekly, joins the regular Hafta gang, that is, Abhinandan Sekhri, Madhu Trehan, Anand Ranganathan, Manisha Pande and Anand Vardhan to discuss this and the ongoing debate on the use of human shields in conflict areas. We also discuss Vijay Mallya's arrest and bail and former Hi...2017-04-2100 mina16z Podcasta16z Podcasta16z Podcast: When Bio Meets Computer ScienceBiology startups have been around for a long time. But the world has changed since that first wave of bio startups, and especially more recently, due to the "peace dividends of the smartphone wars". So what happens when you combine those cheap sensors and compute power -- and apply it to bio? Cheaper costs and Moore's Law-like effects may mean lower barriers to entry, the ability to experiment more often and more easily, and other AWS-like effects for a new wave of bio company founders. But is all this just about cost … or about something more? And ho...2015-07-2641 min