Shows
The Cancer LetterIn The Headlines: A good week for NIH, a bad week for Vinay PrasadWhile doing somewhat-routine reporting on this year’s Senate Appropriations Committee bills, Paul Goldberg, editor and publisher of The Cancer Letter, quickly realized that he was seeing a full bipartisan rejection of President Donald J. Trump’s plan to defund and therefore dismantle biomedical research in the United States.In this episode of In the Headlines, Paul, Jacquelyn Cobb, associate editor, and Claire Marie Porter, reporter, discuss the GOP-led turn of events that reversed the Trump administration’s cuts to NIH, as well as the very public departure of Vinay Prasad from FDA following a snowballing of attack...
2025-08-0627 min
We Want Them Infected PodcastVinay Prasad Fired from the FDA: How It Really Went DownIn this episode, we break down the high-profile firing of Dr. Vinay Prasad from his FDA leadership post. Once hailed as a contrarian voice in medicine, Prasad quickly became a polarizing figure both inside and outside the agency. We explore the tangled web of political infighting, pressure from Big Pharma, the biotech industry, and conspiracy theorists like Laura Loomer—and why this decision may have less to do with science and more with chaos at the top. Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/ The Fine Print The content presented in...
2025-08-041h 09
Post-Hoc LiveWhat will Vinay Prasad's CBER look like?Today, we'll be talking about the news that Vinay Prasad will join FDA as the next director of the Center for Biologics and Research. We'll talk about his past critiques of the agency, his disagreements with former director Peter Marks, and how is tenure might affect vaccine policy, gene therapies, and rare disease companies. I’ll be joined by our senior editor Zach Brennan, who has known Prasad for years, and reporter Lei Lei Wu.
2025-06-1229 min
BioCentury This WeekEp. 296 - Trends in Obesity, Vinay Prasad at FDA, Ovarian Cancer InsightsBiopharmas developing therapies for obesity are looking to a future where the quality of weight loss matters as much as the quantity — what targets and programs could help realize that vision? On the latest BioCentury This Week podcast, BioCentury’s editors discuss the signaling pathways that may exclusively target fat mass while preserving, or even increasing, lean mass — and which companies are playing in the space.The editors also assess what Vinay Prasad’s past comments say about how he might lead FDA’s Center for Biologics Evaluation and Research (CBER) — and examine how investors are evaluating the possibility...
2025-05-1333 min
ConspiritualityBrief: Vinay Prasad’s Pick-me CampaignUCSF epidemiology and biostatistics professor Vinay Prasad's star rose when he compared the US response to Covid-19 to the beginnings of the Third Reich in October, 2021. Though a less famous contrarian than others in the MAHA sphere, the hematologist-oncologist has honed his social media trolling over the past few years, always ready for a fight, evidence be damned.Derek and Julian look at two recent videos that signal Prasad might be angling for a position in a potential RFK Jr-run HHS—and all the misinformation he continues to spread.Show NotesBMJ's Systematic Re...
2025-01-1136 min
Just Asking QuestionsVinay Prasad: What Does RFK Jr. Get Right and Wrong?What does Robert F. Kennedy, Jr. get right and wrong about science, vaccines, and health? Just asking questions.
President-elect Donald Trump announced Robert F. Kennedy, Jr. would be his pick to lead the Department of Health and Human Services, which oversees the Food and Drug Adminstration, National Institutes of Health, Centers for Disease Control, and several other health-related federal agencies. Trump wrote on X that "for too long, Americans have been crushed by the industrial food complex and drug companies who have engaged in deception, misinformation, and disinformation when it comes to Public Health," and that "Kennedy wi...
2024-11-251h 25
The Megyn Kelly ShowMace's Quest to Protect Women's Spaces, and RFK vs. Corporate Media and the Swamp, with Casey Means and Vinay Prasad | Ep. 949Megyn Kelly begins the show by discussing Rep. Nancy Mace's proposal to make sure women's restrooms at the Capitol stay exclusively for biological women, the importance of maintaining privacy and safety for women in public spaces, the solution of gender neutral bathrooms, why now is the time to speak out about protecting women-only spaces from biological men, how Speaker Johnson found the right way to describe the issue and the nuance of it, and more. Then Dr. Vinay Prasad, creator of DrVinayPrasad.com on Substack, joins to talk about what we now know about the COVID vaccines harming young...
2024-11-201h 39
The VPZD ShowTrump Transition, Reproductive Rights, Vaccine TruthAnother live episode, we touch on a BUNCH of stuff, including Trump's transition, possible FDA appointments, RFK Jr., letters we've gotten about reproductive rights, was Harris or her team afraid to have her go on Rogan, a deep dive into COVID infection fatality rate and what to do about vaccines, and MUCH more. Watch the video version here.Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.More...
2024-11-141h 24
Plenary Session - inactive due to federal serviceSystematic Reviews - An Introduction⧸ How to do them⧸ Search Strategies⧸ Common ErrorsLecture on systematic review, given by Vinay Prasad MD MPH to students in the UCSF Training in Clinical Research Program, November 2024.
2024-11-1348 min
The VPZD ShowWhy Trump Won & What It Means For HealthcareRegardless of your political leanings, this live podcast WILL traumatize you 😻. Election reactions, media polarization, what this might mean for healthcare and WAY more than you cared to hear about Peyronie’s disease 🍆🤓. Watch the video version here.Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.More on Vinay.More on Zubin. Learn more about your ad choices. Visit megaphone.fm...
2024-11-091h 40
The VPZD ShowRogan & Trump, Dumb Medical Practices, A VPZD Book Club?In this episode we discuss Joe Rogan/Trump Interview insights, the ‘science’ of polling, irrational COVID policies, erosion of trust in the medical establishment, the dangers of public health dogma, Trump Derangement Syndrome™️, reflections on the US political system, Zubin’s TikTok verification drama, what creates successful social media reach, TikTok’s cringey docs, the impact of shame on medical practice and education, Rogan’s fixation on physical fitness, why Yoga kicks ass, Vinay’s literary review of Elena Ferrante's Neapolitan series, and Zubin’s personal experience with psychedelics (watch THAT video here).Video version of this ep...
2024-10-301h 44Plenary Session - inactive due to federal serviceMasking Mistakes - my panel discussion at the Emory Center for Ethics"Masking Mistakes: Lessons from the Science, Policy, and Coverage of COVID-19", the 2024 Brian Shields Lecture on Institutional Ethics which took place on Monday, October 7, 2024 for the Emory Center for Ethics. A conversation with Carlos Del Rio, MD and Vinay Prasad, MD MPH with moderation by Gerard Vong, DPhil, Director of the MA in Bioethics program.
2024-10-161h 36Plenary Session - inactive due to federal serviceA SM crossover - Cifu, Prasad, MandrolaShould trials have carbon footprint as an endpoint?
2024-05-2745 min
Life Lessons with Dr. BobEp51 What We Can Learn from the Covid-19 Pandemic with Dr. Vinay PrasadDr. Bob sat down recently with the renowned Dr. Vinay Prasad, a professor of epidemiology and biostatistics at UCSF and an expert in hematology oncology to look back on the policies of the last several years. Dr. Prasad, who has authored over 400 peer-reviewed papers and two influential books, unpacks the COVID-19 pandemic, the government's response, mask mandates, and the loss of public faith in the government and medical establishment. Dr. Prasad criticizes the misleading messaging and overconfidence of scientists during the pandemic, emphasizing the importance of considering trade-offs and providing accurate information. He questions the effectiveness of mask...
2024-05-241h 11Plenary Session - inactive due to federal serviceCifu, Mandrola, Prasad - SM crossoverI crossover SM podcast; Harvard med students video, Justice curriculum, Masking half the year
2024-05-1141 min
The Good FightVinay Prasad on What Went Wrong With COVIDYascha Mounk and Vinay Prasad assess the strengths and weaknesses of America’s public health response.
Vinay Prasad MD, MPH is a hematologist-oncologist and Professor in the Department of Epidemiology and Biostatistics at the University of California San Francisco.
In this week’s episode, Yascha Mounk and Vinay Prasad discuss the impact and efficacy of mask mandates and lockdowns; how the stifling of dissenting views among doctors and scientists harmed decision-making; and how we can improve our readiness for the next pandemic.
This transcript has been condensed and lightly edited for clarity.
Please do listen and spread the word about The Good...
2024-04-131h 00
The Good FightVinay Prasad on What Went Wrong With COVIDYascha Mounk and Vinay Prasad assess the strengths and weaknesses of America’s public health response.Vinay Prasad MD, MPH is a hematologist-oncologist and Professor in the Department of Epidemiology and Biostatistics at the University of California San Francisco. In this week’s episode, Yascha Mounk and Vinay Prasad discuss the impact and efficacy of mask mandates and lockdowns; how the stifling of dissenting views among doctors and scientists harmed decision-making; and how we can improve our readiness for the next pandemic.This transcript has been...
2024-04-131h 03ConspiritualityBrief: The “Super Reasonable” Dr. Vinay PrasadA contrarian doctor “just asking questions.” Super reasonable. Certainly not anti-vax, just a regular guy who grievance-mongers about quarantine measures and mocks people afraid of long Covid. Vinay Prasad cuts a different type of figure on the conspiracy-influencer stage. He fits right in with his pal, the charismatic guru-esque Dr. Zubin Damania, and might just pop up in your YouTube feed alongside Andrew Huberman and Peter Attia.Prasad demands unrealistic randomized controlled trial data for everything on his podcast, including protecting ICU patients from Covid via visiting restrictions. Who’s volunteering for that control group?!Julian...
2024-02-2438 minPlenary Session - inactive due to federal serviceCAR T causes MDS??? Manni, Goodman, Raj, PrasadDoes car T cause secondary AML?
We discuss
2023-12-2827 minPlenary Session - inactive due to federal serviceTimothee and Prasad talk 2023 cancer trialsWe talk about 2023 cancer trials
2023-12-2444 minPlenary Session - inactive due to federal serviceAaron Goodman Prasad ASH UPDATESGoodman and I discuss ash updates.
My myeloma talk
https://www.youtube.com/watch?v=jAz84yCnfjQ
2023-12-2052 minPlenary Session - inactive due to federal serviceMandrola and PrasadSubscribe to Sensible Med Pod; This is x over
Post partum depression, orbita 2 and physics vs medicine
2023-12-1749 minPlenary Session - inactive due to federal serviceHawai Keynote - Coffee and colon cancer & Censoring & MorePrasad is back in Hawaii to give another keynote (good thing they cancelled Dallas not Honolulu). I discuss coffee and colon cancer, and censoring, and Lu177 PSMA
2023-10-2345 minPlenary Session - inactive due to federal servicePrasad's lecture gets cancelled/ Cifu Gets COVID a SM crossoverMandrola, Prasad and Cifu are back to discuss the latest drama
2023-10-1654 minPlenary Session - inactive due to federal serviceCoumadin, ECMO, RCTs and moreA far reaching discussion btw Mandrola and Prasad on RCTs, Coumadin, ECMO and RCTs for covid shots
2023-09-1148 minPlenary Session - inactive due to federal servicePrasad and Mandrola discuss recent journal articles/ Republicans/ StentingSimultaneously released on Sensible Medicine. Time to subscribe to Sensible Medicine substack and podcast.
2023-08-2342 minPlenary Session - inactive due to federal serviceSensible Med Crossover - Cifu/ Mandrola/ Prasad & WallenskyI combine two latest tracks on interpreting medical studies, medical boards, 7 doses of vaccine, and finally Walensky. Stay tuned.
2023-04-241h 23Plenary Session - inactive due to federal serviceCochrane Mask Debates - Jefferson/ Heneghan/ PrasadWe explore the fight btw NYTimes, Cochrane, and the last people keeping EBM alive
2023-04-151h 17
EconTalkVinay Prasad on Pharmaceuticals, the FDA, and the Death of DutyOncologist and epidemiologist Vinay Prasad argues that too many very expensive drugs get approved by the FDA that have very limited impact on the lives of patients. Prasad explains the incentives that distort the current system. The general problem, he explains to EconTalk host Russ Roberts, is the death of duty--too many players in the health care landscape and elsewhere stay quiet or do the wrong thing in order to serve themselves.
2023-01-301h 09Plenary Session - inactive due to federal service5.25 - Neurosurgery Grand Rounds by Vinay PrasadI give Grand Rounds to UCSF Neurosurgery on how to read and interpret Neurosurgery Studies
(Video and slides coming soon to YouTube)
Also I discuss Bob Califf's Promotion of Paxlovid
2022-11-031h 12
Ask Dr. DrewHeart Scars & Kids With Myocarditis: Dr. Vinay Prasad on mRNA & CDC’s Advisory Committee on Immunization Practices (ACIP) Vote with Dr. Kelly Victory“Incompetence,” says Dr. Vinay Prasad, responding to reports of today’s vote by the CDC’s Advisory Committee on Immunization Practices (ACIP) that will decide if COVID-19 vaccines should be added to their childhood vaccine schedule – a list that is often required to attend public school.“It will be a catastrophic error if they add it,” Dr. Prasad continued on Twitter. “They will do more in a single day to erode routine vaccination than 25 years of a devoted, irrational movement.”Dr. Vinay Prasad, MD MPH is a practicing hematologist-oncologist and Professor in the Department of Epidemiology and B...
2022-10-231h 17Plenary Session - inactive due to federal service5.20 The Great Colonoscopy DebateCifu, Mandrola and Prasad fight about colonoscopy
2022-10-111h 01Plenary Session - inactive due to federal service4.58 - Myeloma is a broken field - New BLOOD Paper!I am joined by Manni Mohyuddin to talk about How I treat frontline transplant eligible myeloma. Vinay Prasad makes the case the entire field of myeloma is corrupt and broken.
2022-05-141h 02Plenary Session - inactive due to federal service4.52 Vinay Prasad Gives a Lecture on COVID19 to a General AudienceListen in as I give an unscripted lecture to a general audience about COVID-19; What we got right and wrong these last 2+ years.
2022-04-2441 minPlenary Session - inactive due to federal service4.51 - Vinay Prasad is Interviewed by Kristina Jenei About Academic MedicineKristina Jenei becomes the 4th guest host and flips the tables on me, interviewing me about academic medicine and more...
2022-04-221h 19
Ask Dr. DrewTeen COVID-19 Vaccination: Dr. Vinay Prasad on the Risks to Public TrustDr. Vinay Prasad is a hematologist-oncologist who has concerns about the CDC's all-or-nothing approach to teen COVID-19 vaccinations – a policy he believes could cause catastrophic damage to trust in vaccines. Dr. Vinay Prasad, MD MPH is a practicing hematologist-oncologist and Associate Professor in the Department of Epidemiology and Biostatistics at the University of California San Francisco. He studies cancer drugs, health policy, clinical trials and better decision making. Clinically, Dr. Prasad cares for patients with a wide range of benign hematologic and malignant conditions. Website: https://Vinayakkprasad.com Twitter: https://twitter.com/VPrasadMDMPH Podcast: Plenary Session [T...
2022-01-241h 20
The VPZD ShowOmicron Panic, Natural Immunity, Fluvoxamine, Boosters, Fauci (w/ Dr. Marty Makary)Dr. Marty Makary joins the fray for a science & reason SMACKDOWN 🔥 How many Omicrons does this register on the media fear-o-meter? Check out all our shows with MedPage today editor-in-chief Dr. Marty Makary here. And all our shows with UCSF hematologist-oncologist Dr. Vinay Prasad here. And our new joint podcast, The VPZD Show, here. And here's the video version of this interview!Topics & Timecodes:0:00 Intro2:17 Boosters for All?8:47 Young people + Covid, flawed CDC studies?12:45 Natural immunity, Myocarditis, population risk vs. benefit21:15 The narrative of simplicity and...
2021-12-041h 40
The VPZD ShowKids Inside For Thanksgiving? Should Fauci Quit? Boosters 4 All?Dr. Z and Dr. Vinay Prasad get unfiltered about the NY Times recommendations for a safe COVID Thanksgiving, whether Dr. Fauci should quit, and whether a healthy young person should get a Moderna booster, and more!Here's all our other video episodes featuring VP.
Subscribe to "The VPZD Show" on your favorite podcast app.
Check out our new Substack collaboration, "Sensible Medicine" here.
Dr. Prasad's "Plenary Session" podcast.
Dr. Damania's "ZDoggMD Show" podcast.
More on Vinay.
More on Zubin.
Learn more about your ad choices. Visit megaphone.fm/adchoices
2021-11-241h 22
The VPZD ShowMedication, Mandates, Middle GroundIn this inaugural episode of our new collaborative show, Dr. Vinay Prasad (UCSF hematologist/oncologist) and Dr. Zubin Damania (AKA the hospitalist known as ZDoggMD) team up for a medical show designed to bring you up to speed on the weeks events with a nuanced, Alt-Middle perspective.Here's all our other shows featuring VP.
Subscribe to "The VPZD Show" on your favorite podcast app.
Check out our new Substack collaboration, "Sensible Medicine" here.
Dr. Prasad's "Plenary Session" podcast.
Dr. Damania's "ZDoggMD Show" podcast.
More on Vinay.
More on Zubin.
Learn more about your...
2021-11-181h 26
The ZDoggMD ShowDid COVID Break Our Brains? (w/Dr. Vinay Prasad)Sense-making on vaccines and young kids, recognizing groupthink, removing ideology and personal attack from scientific discourse, and much more.Watch all our other shows with Dr. Vinay Prasad here.Transcript, video and more: https://zdoggmd.com/vinay-broken-brain/Topics & Timecodes:0:00 Intro0:15 We turn science debate into good vs. evil, why?6:27 Understanding FDA decision on kids vaccines 5-11, myocarditis etc.12:49 The “Retrospectoscope” and our takes on COVID over the months16:17 The origins of COVID politicization and Tribalism25:41 Should we not treat unvaxxed people or shame un...
2021-10-281h 32
The ZDoggMD ShowBooster Shots, Kids & Masks, Vaccine Mandates, & SCIENCE (w/Dr. Vinay Prasad)Tha’ Notorious VP returns to talk about the numbers around mandates, booster science or lack thereof, masking young kids, and more!Check out Dr. Vinay Prasad’s YouTube channel here and here are the other episodes we’ve done together.Transcript, video and more: https://zdoggmd.com/vinay-mandates/ Topics & Timecodes:0:00 Intro 0:31 The science on masking young children 6:29 Criticizing irrational views held by rational people, kids’ masking 9:47 Bangladesh mask study promoting surgical masks over cloth in adults 13:29 Vaccine mandates, do they make sense to actually imp...
2021-09-151h 18
Plenary Session - inactive due to federal service4.19 Censoring: Not on Facebook, but in Kaplan-Meier CurvesToday's episode is a lecture our host, Dr. Vinay Prasad of University of California San Francisco, gave recently on censoring patients in Kaplan-Meier plots.
Back us on Patreon! www.patreon.com/plenarysession
Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
2021-09-0830 min
The ZDoggMD ShowMyocarditis & Teens: Vaccine Benefit & Risk (w/Dr. Vinay Prasad)Weighing the risk of myocarditis vs. the benefit of vaccinating young people (particularly boys) with the Pfizer mRNA vaccine.
Transcript, video podcast, links to the op-ed and more with UCSF hematologist/oncologist and medical evidence specialist Dr. Vinay Prasad: https://zdoggmd.com/vinay-myocarditis
Your support keeps us independent and mild-to-moderately awesome: https://zdoggmd.com/supporters
Show, podcast, music, support, shop, social media, and email: https://lnk.bio/zdoggmd Learn more about your ad choices. Visit megaphone.fm/adchoices
2021-07-1027 min
Plenary Session - inactive due to federal service4.07 Questions from a Medical Student with Emma Greenstreet and Dr. Vinay PrasadWe have a reverse episode for you today! Emma Greenstreet, a second-year medical student at UCSF, interviews our usual host, Dr. Vinay Prasad on why and how he chose hematology/oncology as a specialty, engaging with criticism, mentorship, medical student rotations, choosing a research project, and urging doctors in academia to aim higher.
Back us on Patreon! www.patreon.com/plenarysession
Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
2021-07-1049 min
The ZDoggMD ShowShould We Be Masking Kids? (w/Dr. Vinay Prasad)We have absolutely no idea whether putting masks on kids is net helpful or harmful, and here's why.
Links to the op-ed, transcript, video, and more from Dr. Vinay Prasad: https://zdoggmd.com/vinay-kids-masking
Your support keeps us independent and mild-to-moderately awesome: https://zdoggmd.com/supporters
Show, podcast, music, support, shop, social media, and email: https://lnk.bio/zdoggmd Learn more about your ad choices. Visit megaphone.fm/adchoices
2021-07-0915 min
The ZDoggMD ShowIvermectin & Aducanumab: Do They Work? (w/Dr. Vinay Prasad)Two doctors analyze the evidence so far on ivermectin for COVID-19 and Aduhelm (aducanumab) for Alzheimer's.
Dr. Vinay Prasad is a UCSF heme/onc doc who specializes in clinical trials and medical decision-making. Video podcast, transcript, links and more: https://zdoggmd.com/vinay-prasad-ivermectin
Your support keeps us independent and mild-to-moderately awesome: https://zdoggmd.com/supporters
Show, podcast, music, support, shop, social media, and email: https://lnk.bio/zdoggmd Learn more about your ad choices. Visit megaphone.fm/adchoices
2021-07-0846 minPlenary Session - inactive due to federal service4.04 Treatment Algorithm for Follicular Lymphoma & Assessing RCTsToday we have a short monologue for you on just a few topics: a treatment algorithm for follicular lymphoma and our host Dr. Prasad's new paper out now in the European Journal of Clinical Investigation: "Reliable, cheap, fast and few: What is the best study for assessing medical practices? Randomized controlled trials or synthetic control arms?"
RCTs or Synthetic Control Arms?: doi.org/10.1111/eci.13580
Back us on Patreon! www.patreon.com/plenarysession
Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
2021-06-2630 minPlenary Session - inactive due to federal service3.88 Behind the Scenes for the One-Year Anniversary of Malignant with Dr. Vinay PrasadToday's episode is hosted by guest Logan Powell, an incoming medical student at the Texas A&M College of Medicine and creator of this podcast's show notes. He reverse interviews our usual host, Dr. Vinay Prasad, in honor of the one-year anniversary release of Dr. Prasad's book "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer". They explore a few behind-the-scenes stories.
Show notes: www.plenarysessionpodcast.com
Listen to Malignant with a free 30-day trial of Audible: www.audible.com/pd/B08864KFHW/?so…ACX0_195112_rh_us
Back us on Patreon! www.patreon.com/plenarysession
Check out our Yo...
2021-06-021h 18Plenary Session - inactive due to federal service3.88 Behind the Scenes for the One-Year Anniversary of Malignant with Dr. Vinay PrasadToday's episode is hosted by guest Logan Powell, an incoming medical student at the Texas A&M College of Medicine and creator of this podcast's show notes. He reverse interviews our usual host, Dr. Vinay Prasad, in honor of the one-year anniversary release of Dr. Prasad's book "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer". They explore a few behind-the-scenes stories.
Show notes: www.plenarysessionpodcast.com
Listen to Malignant with a free 30-day trial of Audible: www.audible.com/pd/B08864KFHW/?so…ACX0_195112_rh_us
Back us on Patreon! www.patreon.com/plenarysession
Check out our Yo...
2021-06-021h 18
Stimulus - Learn Tools to Crush It in Your Medical CareerVinay Prasad Wants to Flip Your Vote | Chemotherapy delusions, overstating benefit, trade offs, and medical reversalVinay Prasad pulls no punches in this wide ranging conversation about the realities (and delusions) about chemotherapy research, principle centered social media engagement, flipping votes, the FDA drug approval process, the importance of early palliative care, the dangers of embellishing therapeutic benefit, medical reversals, effective vs efficacious, and trade offs in decision making. Guest Bio: Dr Vinay Prasad is a practicing hematologist-oncologist and Associate Professor in the Department of Epidemiology and Biostatistics at the University of California San Francisco. He studies cancer drugs, health policy, clinical trials and better decision making. He is author of over 250 academic ar...
2021-02-081h 12
Healthy Skeptic, MDWhich Genetic Tests Are Ready for Prime Time? (And Some Musings on COVID-19) With Dr. Vinay PrasadIn 2018, the FDA authorized the first genetic test that could be marketed directly to consumers – a home test made by 23andme for BRCA mutations to assess breast cancer risk. Since then, the number of genes linked to cancer and other health conditions has continued to increase. Yet what to do with this information has not become any less confusing. In today’s episode, cancer specialist Vinay Prasad, MD, MPH from the University of California, San Francisco explains his anxieties about genetic testing, but also the opportunities. Dr. Prasad also discusses a recent controversial article he wrote suggesting that those who...
2021-02-0545 min
The ZDoggMD ShowRelax After Vax? Masks, Schools, & More w/Dr. Vinay PrasadDr. Prasad returns to talk about why we might relax mask/social distance restrictions responsibly after vaccinating, why the schools need to open yesterday, and our thoughts on The Coddling of the American Mind.
Full video: https://zdoggmd.locals.com/post/368826/vax-chill-masks-off-schools-open-w-dr-vinay-prasad Learn more about your ad choices. Visit megaphone.fm/adchoices
2021-01-221h 01
The ZDoggMD ShowDanish Mask Study, Thanksgiving, COVID Vaccines, & More (w/Dr. Vinay Prasad)Two docs talk LIVE about the dangers of medical black & white thinking when it comes to COVID-19.
Links, video, and more: https://zdoggmd.com/vinay-prasad-4
We talked Danish mask study, Thanksgiving public health absolutism and harm reduction strategies, the latest ways to think about the new COVID vaccines, scientific censorship, political polarization in science, Dr. Scott Atlas, and much more.
Vinay Prasad MD MPH is a practicing hematologist-oncologist and Associate Professor of Medicine at the University of California San Francisco. He studies cancer drugs, health policy, and clinical trials and better decision making. He is author of these academic articles...
2020-11-241h 24
The Peter Attia DriveVinay Prasad, M.D., M.P.H: Hallmarks of successful cancer policy Vinay Prasad is a practicing hematologist-oncologist who doubles as a “meta-researcher,” studying the quality of medical evidence, health policy, and clinical trials. In this episode, Vinay discusses the differences in clinical treatment from the existing medical evidence, often leading to useless, or even harmful, outcomes for patients. With a focus in oncology, he takes a deep dive into the field’s structural problems, which include the disconnect between progress and funding, drug costs, and financial conflicts of interest. He concludes with his “six hallmarks of successful cancer policy” as a potential roadmap to sustained progress against cancer and a way to avo...
2020-10-192h 12
The ZDoggMD ShowReopening Schools & The Dangers Of COVID Soundbites (w/Dr. Vinay Prasad)Why a data-driven, holistic, and nuanced approach to our COVID-19 response is long overdue. Vinay Prasad MD MPH is a practicing hematologist-oncologist and Associate Professor of Medicine at the University of California San Francisco. He studies cancer drugs, health policy, and clinical trials and better decision making and hosts the Plenary Session podcast. In this encore podcast we talk about the first presidential debate and the foibles thereof, the goals of healthcare reform and single payer upside vs. downside, why soundbite news and social media culture has failed us, why data and being able to change our minds matters...
2020-09-301h 05
The ZDoggMD ShowDo White Doctors Kill Black Babies, Cancel Culture, & Authenticity In Medicine (w/Dr. Vinay Prasad)Norman Wang...#MedBikini...do white docs kill black babies? Triggered yet? Applying a rationalist framework to emotionally charged "research" should be a priority for everyone, but too often we're failing. Dr. Vinay Prasad, UCSF hematology-oncology maven and host of the Plenary Session podcast, returns for a truly authentic discussion on the LACK of authenticity in healthcare. This is required listening for anyone pursuing a career in medicine. Dr. Prasad has written two books, Ending Medical Reversal and Malignant.Links to Dr. Prasad's books and video: zdoggmd.com/vinay-prasad-2Your support makes what we do possible...
2020-09-081h 28Plenary Session - inactive due to federal service3.09 COVID-19 Risk, Financial Toxicity, & HALT-IT for Journal Club with Fellow Dr. Justine RyuWe start this week's episode by revisiting our discussion from last week on the PNAS study on racial concordance and birthing mortality. We continue our theme of critical appraisal by then tearing apart the recent paper published in BMJ titled "Two metres or one: what is the evidence for physical distancing in covid-19?" and its inability to support its colorful figures. We end the monologue with a few thoughts on academics who somehow author one paper a week. Finally, we turn to the last two segments of the show: the first is a discussion with Dr. Bishal Gyawali on his...
2020-08-291h 24Plenary Session - inactive due to federal service3.08 Racial Concordance in Birthing Mortality & HERO for Journal Club with Fellow Dr. Michael BurnsThis week we take a deep dive into two recently published studies, their surrounding controversy, and the broader implications. The first study was published in the journal Proceedings of the National Academy of Sciences of the USA and is titled "Physician–patient racial concordance and disparities in birthing mortality for newborns". The second was published in the New England Journal of Medicine and is titled "Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer", commonly known as the HERO trial. We discuss the HERO trial with Dr. Michael Burns of Northwestern as part of our new segment, Journal Club with a...
2020-08-221h 33Plenary Session - inactive due to federal service3.07 Lung Cancer Omics and Mortality, PPIs and COVID-19, & RECIST with Dr. Elizabeth EisenhauerWe have a lot in store for you this week! We start off by evaluating two recently published studies: "Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer" (published in the Journal of Clinical Oncology: Oncology Practice) and "The Effect of Advances in Lung-Cancer Treatment on Population Mortality" (published in the New England Journal of Medicine). We talk a bit about tracking down the validity of a reference. We sit down with Dr. Branden Tarlow to discuss his thoughts on PPIs and COVID-19 acquisition. Finally, we conclude the episode by interviewing Dr. Elizabeth Eisenhauer of Queen's University in...
2020-08-152h 42Plenary Session - inactive due to federal service3.06 COVID-19 Vaccine Access, ADAURA, QOTW, & Journal Club with Fellow Dr. Karine TawagiWe start this week's episode by discussing access to investigational COVID-19 vaccines and recapping the problems with the ADAURA study. We transition from there to a Question of the Week with medical student Audrey Tran of Oregon Health & Science University. Finally, we introduce a new segment - Journal Club with a Fellow. In this inaugural segment we invite Dr. Karine Tawagi of the Oschner Clinic in Louisiana to the podcast to talk about IMbrave150.
IMbrave150: doi.org/10.1056/NEJMoa1915745
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2020-08-081h 55Plenary Session - inactive due to federal service3.05 LIVE! A Midsummer Night's StreamThis is the recording of a LIVE episode of Plenary Session in which Dr. Sue S Yom interviewed our host, Dr. Vinay Prasad, on how he built his career and how he conceptualizes his work. There's also a surprise guest near the end! Thank you to Dr. Kaleigh Doke, Dr. Brian Kavanagh, and the Virtual Visiting Professor Network for hosting this special episode.
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2020-07-311h 16Plenary Session - inactive due to federal service3.04 Listener Questions & MedTwitter and Risk-Benefit Profile of Ramucirumab with Dr. Bishal GyawaliThis week we respond to several questions sent in by listeners and then we interview Dr. Bishal Gyawali of Queen's University in Kingston, Ontario, Canada on MedTwitter, other recent events, and his recently published paper titled "Assessing the risk-benefit profile of ramucirumab in patients with advanced solid tumors: A meta-analysis of randomized controlled trials".
Ramucirumab: doi.org/10.1016/j.eclinm.2020.100458
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2020-07-241h 31Plenary Session - inactive due to federal service3.03 The National Lung Matrix Trial & the Major Flaw of the SPRINT Trial with Dr. Mark FriedbergThis week we discuss two major papers: The first was just recently released in Nature and it's titled "The National Lung Matrix Trial of personalized therapy in lung cancer". The second is a few years old, but exemplifies the importance of trial design. We discuss the second paper, titled "A Randomized Trial of Intensive versus Standard Blood-Pressure Control" and published in the New England Journal of Medicine with Dr. Mark Friedberg, a health policies and performance measurement researcher.
National Lung Matrix Trial: doi.org/10.1038/s41586-020-2481-8
SPRINT: doi.org/10.1056/NEJMoa1511939
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...
2020-07-181h 09Plenary Session - inactive due to federal service3.02 BONUS! National Clinician Scholars Program with Dr. Hilary SeligmanThis week's BONUS episode is a discussion of the National Clinician Scholars Program with Dr. Hilary Seligman, the head of the program at University of California, San Francisco. The deadline for the application for the 2021-2023 cohort is July 15, 2020 (very soon!), though there may be some leniency due to the pandemic.
National Clinician Scholars Program: https://nationalcsp.org/
UCSF National Clinician Scholars Program: https://nationalscholars.ucsf.edu/
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2020-07-1434 minPlenary Session - inactive due to federal service3.01 Risk of COVID-19 Among Users of PPIs, Time to Treatment Initiation, & Dr. Lynora SaxingerThis week we discuss recent research (and the accompanying Twitter thread) on the risk of COVID-19 among users of proton pump inhibitors (PPIs). We also hold a philosophical discussion on the research surrounding time to treatment initiation (TTI) in cancer medicine. We end the episode with an interview with Dr. Lynora Saxinger of the University of Alberta, Edmonton, a specialist in Infectious Diseases.
PPIs and risk of COVID-19: https://twitter.com/BrennanSpiegel/status/1280527527325265920
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2020-07-111h 41Plenary Session - inactive due to federal service2.60 BONUS! Cancer Meta-Research 101: The Lay of the Land of Cancer ResearchThis BONUS episode is the recording of a lecture given on June 18, 2020 as part of Stanford's METRICS International Forum. METRICS stands for Meta-Research Innovation Center at Stanford University. This lecture is geared towards a broad audience and aims to provide a general sense of current cancer research. The lecture is titled "Cancer Meta-Research 101".
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2020-07-0752 minPlenary Session - inactive due to federal service2.59 The Best Doctor, Selinexor, & Annotation Services for NGS with Drs. Katsoulakis and KelleyThis week we respond to some listener feedback from Dr. Christopher Booth and use it to talk about how to be the best hematologist-oncologist. We also discuss the SADAL study on Selinexor for patients with relapsed refractory diffuse large B-cell lymphoma, as published in The Lancet Haematology.
Finally, we interview Drs. Eva Katsoulakis and Michael Kelley on their recent paper out in the Journal of Clinical Oncology: Precision Oncology, titled "Comparison of Annotation Services for Next-Generation Sequencing in a Large-Scale Precision Oncology Program".
Selinexor: doi.org/10.1016/S2352-3026(20)30120-4
Annotation Services: doi.org/10.1200/PO.19.00118
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2020-07-031h 15Plenary Session - inactive due to federal service2.58 RECOVERY & Twitter, Academic Debate, and Transitioning Your Career with Dr. Andrae VandrossThis week we briefly cover updates on the RECOVERY trial before segueing into an interview with Dr. Andrae Vandross on Twitter (specifically #medtwitter), academic discussions, and changing your career to find your calling.
RECOVERY: www.recoverytrial.net/
Malignant audiobook: www.audible.com/pd/B08864KFHW/?so…ACX0_195112_rh_us
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2020-06-271h 21Plenary Session - inactive due to federal service2.57 RECOVERY, Clinical Trials in the US, EFS, Writing, Dr. Raj Chetty, & Dr. Ian TannockThis week's episode is jam-packed with topics! We talk about the RECOVERY trial, the U.S. clinical trial infrastructure, event-free survival (EFS) and cost of care in acute myeloid leukemia, how long it takes to write papers in academic medicine, threats to public health officials, and the application to medicine of Dr. Raj Chetty's work in economics. Finally, we interview this week's special guest, Dr. Ian Tannock, on docetaxel, prostrate cancer, clinical trial appraisal, and his career in medicine.
RECOVERY: https://www.recoverytrial.net/
EFS in AML: doi.org/10.1182/bloodadvances.2019001150
Malignant audiobook: https://www.audible.com/pd/B08864KFHW/?source...
2020-06-202h 14Plenary Session - inactive due to federal service2.56 HER2CLIMB & Misinformation and Disinformation with Dr. Cailin O'ConnorThis week we tackle the topic of tucatinib in HER2-positive breast cancer with brain metastases. We also interview Dr. Cailin O'Connor of the University of California Irvine on her research on misinformation and disinformation. We discuss her recent article in the Boston Review, titled "Hydroxychloroquine and the Political Polarization of Science", as well as her extensive body of work.
HER2CLIMB: doi.org/10.1200/JCO.20.00775
Hydroxychloroquine: http://bostonreview.net/science-nature-politics/cailin-oconnor-james-owen-weatherall-hydroxychloroquine-and-political
The Dynamics of Retraction in Epistemic Networks: http://philsci-archive.pitt.edu/17088/
How Misinformation Spreads: https://www.scientificamerican.com/article/how-misinformation-spreads-and-why-we-trust-it/
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2020-06-121h 02Plenary Session - inactive due to federal service2.55 Hydroxychloroquine for COVID-19, ASCO, QOTW, Private Equity in Medicine with Dr. Jane ZhuWe start this week's episode by covering some recent research: After thoroughly critiquing the recent randomized trial of hydroxychloroquine for postexposure prophylaxis for COVID-19, we then discuss the five abstracts selected for plenary sessions at the recent virtual meeting of the American Society of Clinical Oncology. We transition from there to a Question from a Medical Student with Audrey Tran of Oregon Health & Science University on the recent decision to make the USMLE Step 1 exam pass/fail. Finally, we end with an interview with Dr. Jane Zhu, also of OHSU, on her current research and her new paper published in...
2020-06-052h 06
The ZDoggMD ShowStop Using Cancer Treatments That Don't Work (w/Dr. Vinay Prasad)Dr. Prasad is a heme/onc doc and associate professor of medicine at UCSF; we talk about why we need a HIGHER bar, not a lower one, to show that what we do in medicine actually works.
Links, video, transcript, and more at https://zdoggmd.com/vinay-prasad
Malignant:
https://www.amazon.com/Malignant-Policy-Evidence-People-Cancer/dp/1421437635/
Ending Medical Reversal:
https://www.amazon.com/Ending-Medical-Reversal-Improving-Outcomes/dp/1421429047/
Plenary Session podcast:
https://soundcloud.com/plenarysession
Your support makes what we do possible! Join the SuperPac and get exclusive content, live discussions, and other crazy perks:
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Facebook: http...
2020-06-021h 06Plenary Session - inactive due to federal service2.54 Classical Hematology Chat on Thrombosis in COVID-19 & Drugs for COVID-19 with Dr. Walid GelladThis week we talk all things COVID-19! We start with an in-depth Classical Hematology Chat with Dr. Sven Olson and Dr. Joseph Shatzel of Oregon Health & Science University on thrombosis and anticoagulation in COVID-19, touching on a number of recent studies. We then turn to a conversation with Dr. Walid Gellad of the University of Pittsburgh on new pharmaceutical treatments for COVID-19.
Tang et al. paper: doi.org/10.1111/jth.14768
Prospective autopsy study: doi.org/10.7326/M20-2566
COVID-19 compared to H1N1: doi.org/10.1056/NEJMoa2015432
Hypercoagulability of COVID-19: doi.org/10.1111/jth.14850
JACC letter: doi.org/10.1016/j.jacc.2020.05.001
JACC podcast: https://podcasts...
2020-05-312h 07Plenary Session - inactive due to federal service2.53 Why Agreeing 65% with Someone is Important & COVID-19 Health Policy with Dr. Daniel MorganThis week we discuss why being open-minded enough to agree partially with someone - instead of taking an all-or-nothing approach to a discourse - is important. We also sit down with epidemiologist Dr. Daniel Morgan of the University of Maryland School of Medicine to critique the public health policy concerning COVID-19 transmission.
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2020-05-231h 04Plenary Session - inactive due to federal service2.52 Malignant Audiobook, PROfound trial, & Literature and Medicine with Dr. Adam CifuThis week we have an announcement -- the audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer", written and narrated by our host Vinay Prasad, is available now on Amazon, iTunes, and Audible!
We also have an in-depth journal club for you on the findings of the PROfound trial as published in a new paper out in the New England Journal of Medicine titled "Olaparib for Metastatic Castration-Resistant Prostate Cancer".
Finally, we end the episode with an interview with Dr. Adam Cifu of the University of Chicago on literature, medicine, maintaining a feeling of normalcy and...
2020-05-161h 43Plenary Session - inactive due to federal service2.51 BONUS! Clinical Trials Part 3This BONUS lecture was a talk given to the Hematology/Oncology fellows at Oregon Health & Science University. It's part three of a three-part series on clinical trials.
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2020-05-131h 00Plenary Session - inactive due to federal service2.50 Neil Ferguson, Ending Lockdown, & Updates on COVID-19 Management with Dr. Benjamin SingerThis week's topic is all things COVID-19 -- we discuss the viral scandal of British epidemiologist Neil Ferguson's actions and how it reflects (or doesn't) on his work, we talk about the nuances of how to end lockdowns, and we bring back Dr. Benjamin Singer, a pulmonary and critical care physician at Northwestern University, to address updates in the ICU management of COVID-19.
Invisible Pandemic: doi.org/10.1016/S0140-6736(20)31035-7
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2020-05-081h 06Plenary Session - inactive due to federal service2.49 COVID-19 Contrarians, Remdesivir, & Book Club on "Malignant" with OHSU HemOnc FellowsThis week we begin with a monologue on the recent controversy surrounding Dr. John Ioannidis's published opinions on the COVID-19 pandemic. We end with a group discussion with Oregon Health & Science University's Hematology/Oncology fellows on our host's, Vinay Prasad's, new book "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer."
Expressing different views on COVID-19: https://www.statnews.com/2020/04/27/hear-scientists-different-views-covid-19-dont-attack-them/
Malignant: www.amazon.com/Malignant-Policy-Evidence-People-Cancer/dp/1421437635
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2020-05-021h 26Plenary Session - inactive due to federal service2.48 BONUS! Introduction to Malignant: How Bad Policy and Bad Evidence Harm People with CancerThis week we have a BONUS episode for you! As a teaser to the forthcoming audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer" by Dr. Vinay Prasad (our host), Audrey Tran and Ian Straehley have set the introduction of the book to music they composed and arranged themselves.
You can buy the print version of Malignant from Amazon: https://www.amazon.com/Malignant-Policy-Evidence-People-Cancer-dp-1421437635/dp/1421437635/
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2020-04-2520 minEconTalkVinay Prasad on Cancer Drugs, Medical Ethics, and MalignantOncologist, author, and podcaster Vinay Prasad talks about his book Malignant with EconTalk host Russ Roberts. Prasad lays out the conflicts of interest and scientific challenges that make drugs that fight cancer so disappointing at times. The conversation looks at how policy changes might improve the incentives facing doctors, pharmaceutical companies, and patients.
2020-04-201h 18Plenary Session - inactive due to federal service2.47 Remdesivir, Cloth Masks, & Incentives for COVID-19 Drug Development with Dr. Ameet SarpatwariThis week we start with an in-depth monologue on various new developments surrounding COVID-19, specifically the new study in NEJM on the compassionate use of remdesivir as well as the CDC's advice for the general public to wear cloth masks. We end with an interview with Dr. Ameet Sarpatwari of Harvard Medical School on how to create a more effective pharmaceutical system, the CREATES Act of 2019, developing fair and equitable drugs to treat COVID-19, and how to create a just system that balances the need for innovation with the need for access. Dr. Ameet Sarpatwari is the Assistant Director of...
2020-04-171h 16Plenary Session - inactive due to federal service2.46 Psychology Unearthed by COVID-19 Precautions & Polygenic Risk Score with Dr. Venk MurthyThis week we have a far-reaching monologue on COVID-19 and how people are reacting to the public health recommendations concerning COVID-19 (such as cancelling conferences and school, maintaining 6+ feet of distance, wearing cloth masks). We end with an insightful interview with Dr. Venk Murthy on polygenic risk score and, at the end, a bit about how the world of science is failing to combat hype.
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2020-04-111h 32Plenary Session - inactive due to federal service2.45 Viral Spread of SARS-CoV-2, Rationing Resources, "Evidence Fiasco", & Classical Hematology ChatThis week we discuss several recent articles on the novel coronavirus (SARS-CoV-2) and COVID-19, specifically Dr. Siddhartha Mukherjee's article on the history and science of humanity's history with viruses, Dr. Ezekiel Emanuel's essay on how to fairly allocate dwindling medical resources during this global pandemic, and Dr. John Ioannidis's article on the "evidence fiasco" that has been our response to COVID-19. We end the episode with a Classical Hematology Chat with Drs. Sven Olson and Joseph Shatzel.
Dr. Mukherjee's article: https://www.newyorker.com/magazine/2020/04/06/how-does-the-coronavirus-behave-inside-a-patient
Allocation of Medical Resources: doi.org/10.1056/NEJMsb2005114
Dr. Ioannidis's article: https://www.statnews.com/2020/03/17...
2020-04-021h 26Plenary Session - inactive due to federal service2.44 ICU Management of COVID-19 with Dr. Benjamin SingerThis week we discuss management of COVID-19 in the intensive care unit with Dr. Benjamin Singer, a pulmonary and critical care physician at Northwestern University. We discuss medications, PPE, ventilators, and more!
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2020-03-2637 minPlenary Session - inactive due to federal service2.43 BONUS! Novel Coronavirus and the COVID-19 Response in Oregon with Dr. John TownesThis bonus episode is an interview from March 16, 2020 with Dr. John Townes, the Interim Head for the Division of Infectious Disease and the Medical Director for Infection Prevention and Control here at Oregon Health & Science University. We talk about the novel coronavirus and how healthcare professionals are responding to the COVID-19 pandemic, with a focus on Oregon.
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2020-03-1841 minPlenary Session - inactive due to federal service2.42 Quality-of-Life Measurement in Oncology, KnowYourTumor, & Question of the WeekThis week we discuss two recent papers -- one we praise, one we condemn -- and then we turn to a question of the week with medical student Audrey Tran on self-improvement and "refining conviction". The first paper is titled "Patient Experience Captured by Quality-of-Life Measurement in Oncology Clinical Trials" and the second is titled "Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial".
Quality of Life Measurement: doi.org/10.1001/jamanetworkopen.2020.0363
KnowYourTumor: doi.org/10.1016/S1470-2045(20)30074-7
Vinay's new book, Malignant: www.amazon.com/Malignant-Policy-…cer/dp...
2020-03-171h 08Plenary Session - inactive due to federal service2.41 BONUS! Clinical Trials Part 2: Crossover and Control ArmsThis BONUS lecture was a talk given to the Hematology/Oncology fellows here at Oregon Health & Science University. It's part two of a three-part series on clinical trials. This talk is on clinical trial design, specifically crossover and control arms.
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2020-03-1151 minPlenary Session - inactive due to federal service2.40 BEACON part 2, NALA, & Molecular Pathology and Next-Generation Sequencing with Dr. David CarrThis week we revisit BEACON! The authors of the BEACON study have responded to the Letter to the Editor our host Dr. Vinay Prasad submitted to the New England Journal of Medicine, and we share our thoughts on what they said. We then turn to the FDA's recent approval of neratinib in combination with capecitabine for HER2-positive breast cancer, based on the phase III NALA trial. Finally, we interview Dr. David Carr, a Molecular Pathology Fellow at UC San Diego, on his work in general and, specifically, next-generation sequencing.
BEACON Letters to the Editor: www.nejm.org/doi/full/10.1056...
2020-03-051h 09Plenary Session - inactive due to federal service2.39 Effectiveness of Newer-Generation Antidepressants with Dr. Michael HengartnerOur guest this week is Dr. Michael Hengartner of the Zurich University of Applied Sciences. We interview him on his work studying the long-term consequences and effectiveness of newer-generation antidepressants - specifically focusing on selective serotonin reuptake inhibitors (SSRIs).
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2020-02-2842 minPlenary Session - inactive due to federal service2.38 KEYNOTE-048, Academic Currency, & Trials in Low/Mid-Income Countries with Dr. Bishal GyawaliWe start this episode by diving deep into KEYNOTE-048, the randomized, open-label, phase 3 study of pembrolizumab alone or with chemotherapy v.s. cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (HNSCC). We transition from there to a continued discussion on careerism in academia and how the motivation behind publishing papers should always stem from the drive to disseminate information, not from the drive to advance your own career. We end the episode with an interview with Dr. Bishal Gyawali of Queen's University in Kingston, Canada on his recent paper out in Nature Cancer...
2020-02-1951 minPlenary Session - inactive due to federal service2.37 Careerism, Presenting Abstracts, Twitter and the K-Index, & Classical Hematology ChatWe have a full slate for you this week! We discuss careerism in medicine, presenting abstracts at conferences, #MedTwitter, and Dr. Califf's opinions on the K-Index. We conclude the episode with our first-ever Classical Hematology Chat, featuring our host Dr. Vinay Prasad, Dr. Sven Olson, and Dr. Joseph Shatzel. The chat is on sickle cell disease.
"A Perspective on the K-Index": doi.org/10.1016/j.jaccas.2020.01.003
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2020-02-151h 09Plenary Session - inactive due to federal service2.36 Thought Leaders, NELSON, & Reliance on P Values in Cancer Trials with Dr. Sam RubinsteinThis week we discuss the concept of "thought leaders" and we examine the conclusions about volume CT screening for lung cancer from the NELSON trial. We end with an interview with Dr. Sam Rubinstein, a hematology/oncology fellow at Vanderbilt University Medical Center, on his new paper published in JAMA Network Open titled "Indication of Measures of Uncertainty for Statistical Significance in Abstracts of Published Oncology Trials: A Systematic Review and Meta-analysis".
NELSON: doi.org/10.1056/NEJMoa1911793
Measures of Uncertainty: doi.org/10.1001/jamanetworkopen.2019.17530
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2020-02-0859 min
Plenary Session - inactive due to federal service2.35 BONUS! How to Keep Up with the New Information in MedicineThis BONUS episode is the recording of a lecture given to medical students titled "How to Keep Up with the New Information in Medicine." It's a primer on the steps healthcare professionals need to take in order to keep abreast of the latest medical findings.
Vinay's new book, Malignant: www.amazon.com/Malignant-Policy-…cer/dp/1421437635
Back us on Patreon! www.patreon.com/plenarysession
2020-01-311h 00
Plenary Session - inactive due to federal service2.34 Red Light, Pola for DLBCL, Hem/Onc Question of the Week, & TAILORx with Dr. Ali KhakiWe have a variety of topics for you this week! We tackle red light therapy, polatuzumab olatuzumab vedotin in relapsed or refractory diffuse large b-cell lymphoma; we have a hematology/oncology question of the week from Dr. Emerson Chen of OHSU; and we sit down with Dr. Ali Khaki of the Fred Hutchinson Cancer Research Center to discuss his recent paper critiquing TAILORx.
Pola for DLBCL: doi.org/10.1200/JCO.19.00172
Financial COI on Twitter: doi.org/10.1001/jamainternmed.2016.8467
Ignoring Valuable Data: doi.org/10.6004/jnccn.2019.7363
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2020-01-241h 32
Plenary Session - inactive due to federal service2.33 Olaparib and POLO & the Classical Fallacies of Cancer Screening with Dr. H Gilbert WelchThis week we're treating you to a recording of the Grand Rounds lecture on overdiagnosis and cancer screening that Dr. H Gilbert Welch gave at Oregon Health & Science University on October 30, 2019. Before the lecture, we take a moment to reiterate with renewed vigor our distaste for the POLO trial (first discussed in episode 1.64).
POLO: doi.org/10.1056/NEJMoa1903387
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2020-01-161h 13
Plenary Session - inactive due to federal service2.32 BONUS! Clinical Trials Part 1: Thinking Better About Cancer MedicineThis BONUS lecture was a talk given to the Hematology/Oncology fellows here at Oregon Health & Science University. It's part one of a three-part series on clinical trials, titled "Thinking Better About Cancer Medicine".
Back us on Patreon! www.patreon.com/plenarysession
2020-01-1153 min
Plenary Session - inactive due to federal service2.31 Listener Questions, Responsibility of Reviewers, & Duration of Response with Dr. Bishal GyawaliThis week we answer a few questions: the first is from Patreon backer, Harry Hong, on Kaplan-Meier curves. The second is from a student at Mount Sinai Medical School who reached out with some ethical questions they had after the ASH annual meeting on the obligations and responsibilities of peer reviewers. Finally, we end the episode with an interview with Dr. Bishal Gyawali of Queens University in Kingston, Ontario, Canada on his new paper out today in the Journal of the National Comprehensive Cancer Network titled "Response Rates and Durations of Response for Biomarker-Based Cancer Drugs in Nonrandomized Versus Randomized...
2020-01-0840 min
Plenary Session - inactive due to federal service2.29 Time from Diagnosis to Treatment in AML and Real-World Data with Dr. Sherrie AspinallThis week we wonder incredulously how this abstract from ASH titled "Time from diagnosis to treatment does not affect outcome in intensively treated patients with newly diagnosed acute myeloid leukemia" was selected as one of the top abstracts from the conference. In the second half of the episode we interview Dr. Sherrie Aspinall of the Veterans Administration on how to use real-world data. Her new paper is titled "Use of targeted therapies for advanced renal cell carcinoma in the Veterans Health Administration".
Time from diagnosis to treatment in AML: https://ashpublications.org/blood/article-lookup/doi/10.1182/blood-2019-123717
Targeted therapies for...
2019-12-271h 09
Plenary Session - inactive due to federal service2.16 FLAURA & What Truly Matters in the Career of an Academic Physician with Dr. Vinay PrasadThis week we break down the limitations of the recent FLAURA trial and then we're back in the Plenary Session Mobile Command Unit! We have a special guest host, Dr. Christopher Booth of Queen's University in Kingston, Ontario, Canada. He and Dr. Bishal Gyawali, also of Queen's University, conduct a reverse interview with our usual host, Dr. Vinay Prasad of Oregon Health & Science University, on his career, the formation of Plenary Session, and what truly matters in the career of an academic physician.
FLAURA: doi.org/10.1056/NEJMoa1713137
Price of an Anticancer Drug: doi.org/10.1001/jamainternmed.2017.3601
Simply Measurable or Clinically Meaningful...
2019-10-031h 37
The Week in Health Law118. 100,000 Airplanes. Guest, Vinay Prasad.Renowned hematologist-oncologist, researcher, and writer Vinay Prasad joins us to discuss his sternly-held views on modern clinical and research practice. We discuss the effectiveness (or not) of cancer screening, a more realistic take on the cancer moonshot, and the continual conflicts of interest issues in medicine-issues that maybe are not solvable with transparency laws.
2017-11-1100 min