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Biocrates Life Sciences

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The Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Haley ChatelaineEarly career scientist episode: Vitamins & metabolic syndrome Haley Chatelaine s a post-doctoral fellow at the NIH’s National Center for Advancing Translational Sciences (NCATS, USA) Favorite metabolite Cytosine - but also Vitamin D Paper we discussed in this episode Paper on the absorption of fat soluble vitamins in patients with metabolic syndrome | Vitamin A and D Absorption in Adults with Metabolic Syndrome versus Healthy Controls: A Pilot Study Utilizing Targeted and Untargeted LC–MS Lipidomics Learn more about MANA-ECM Let Arpana Vaniya and Nicole Prince know you appreciate their effort to p...2023-10-031h 03The Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Sapna SharmaMulti-omics & type 2 diabetes Sapna Sharma is group leader at Technical University Munich (TUM) in Germany Favorite metabolite lysophosphatidylcholines (LPCs) Papers we discussed in this episode Effect of BMI on type 2 diabetes | Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes More on the KORA cohort discussed in this episode and in the first paper. Paper on medication associations with multiple omics | Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models More on the IMI-direct project "There is enough data, but th...2023-09-0551 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Karel KaleckýBiobanks & neurodegenerative diseases Karel Kalecký is postdoctoral research associate at the Institute of Metabolic Disease, Baylor Scott & White Research Institute in Dallas, TX (USA) Favorite metabolite Betaine (trimethylglycine) Papers we discussed in this episode One-Carbon Metabolism in Alzheimer’s Disease and Parkinson’s Disease Brain Tissue Targeted Metabolomic Analysis in Alzheimer's Disease Plasma and Brain Tissue in Non-Hispanic Whites Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com Finally available - Ali...2023-08-0154 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Gary PattiFlux metabolomics & cancer Garry Patti is Professor of Chemistry and of Genetics and Medicine at Washington University in St.Louis MO (USA) Favorite metabolite lactate Paper we discussed in this episode Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver "Cancer cells demonstrate a remarkable degree of metabolic plasticity." Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com Finally available - Alices first book The...2023-07-0445 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Rachel KellyEpidemiology & asthma Rachel Kelly is associate professor at the Brigham and Women's Hospital in Boston MA (USA) Favorite metabolite sphingosine-1-phosphate Papers we discussed in this episode Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts Phenotypically driven subgroups of ASD display distinct metabolomic profiles Activities in consortia EnviroGenomarkers COMETS – The consortium of metabolomics studies COMETS analytics On similarity network fusion "Metabolomics is its own beast. You can’t treat it in the...2023-06-0648 minTheSugarScience Podcast- curating the scientific conversation in type 1 diabetesTheSugarScience Podcast- curating the scientific conversation in type 1 diabetesEpisode 187: Stefan Ledinger, Director, BiocratesIn this episode, Stefan Ledinger joins us to discuss T1D as a complex metabolic disease: metabolomics as a tool to explore pathophysiology and enable personalized medicine. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! 2023-05-1644 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Jennifer KirwanTranslating metabolomics to the clinics & quality control Jennifer Kirwan is Head of the Metabolomics Platform at the Berlin Institute of Health at Charité (Germany) Favorite metabolite Melatonin, a close relative of tryptophan, Jennifer Kirwan’s favorite metabolite at MetSoc last year and the metabolite chosen by our previous guest David Wishart! Papers we discussed in this episode Translating metabolomics into clinical practice Don’t forget to send your constructive criticism on this opinion piece in a comment via LinkedIn Identification and validation of small molecule analytes in mouse plasma by li...2023-05-0252 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - David WishartDatabases & the place of metabolomics in the clinics Dr. David Wishart Professor, Faculty of Science - Biological Sciences, University of Alberta, Canada Wishart group @UAlberta Favorite metabolite tryptophan Papers we discussed in this episode Emerging applications of metabolomics in drug discovery and precision medicine Towards a Rosetta stone for metabolomics: recommendations to overcome inconsistent metabolite nomenclature David Wishart’s talk at the event on Pan-cohort studies in October 2022 “Why targeted metabolomics is essential for population health” Sign up for The Metabolomist mailin...2023-04-1842 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Robert AhrendsLipid quantification & data visualization Dr. Robert Ahrends PI Lipidomics at the Institut für Analytical Chemistry, University Vienna, Austria Ahrends group @UniVie Favorite lipid lyso-sphingomyelin Discussed paper by Peng et. al. Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome Lipidomics pioneers mentioned in the interview Shorthand nomenclature developed by Gerhard Liebisch With the corresponding text from the interview There was great work done on lipids in the 1980’s and 1990’s already. People like Britta Brüger, Andrej...2022-10-0444 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Hannelore DanielNutrition & microbiome Prof. emer. Hannelore Daniel Department of Nutrition and Food Sciences Hannelore Daniel @TUM (German) Favorite metabolite lanthionine Discussed paper by Krug et. al. The dynamic range of the human metabolome revealed by challenges Cited paper on sugar metabolomics by Mack et. al. Exploring the Diversity of Sugar Compounds in Healthy, Prediabetic, and Diabetic Volunteers Other resources Talk on Gut Microbiome: Myths and Metabolites by Prof. Hannelore Daniel (given at the 8th Munich Metabolomics Symposium - November 2021) ...2022-09-0657 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Karsten SuhremGWAS & metabolite ratios Professor of Physiology and Biophysics Director of Bioinformatics Core at Weill Cornell Medicine-Qatar Suhre Lab @ Weill CornellVirtual metabolomics core facility Discussed paper by Gieger et. al.Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum Karstens blog about metabolomics, genomics, and where the two fields meethttp://www.metabolomix.com/ mGWAS server (collaboration project) http://metabolomics.gwas.eu Other resources discussed in the podcast in github Sign-up for The Metabolomist e-mail list2022-08-0254 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Metabolomics2022 FeatureFavorite metabolites of Metabolomist listeners Across these recordings, you will hear about the polar metabolites and the lipids that make the hearts of fourteen Metabolomists beat for their research. In this special episode, we learn more about pyruvate, gamma-hydroxybutyric acid (GHB), glutathione, branched-chain alpha keto acids (BCKAs), tryptophan, glutamine, glutamate, nicotinamide adenine dinucleotide (NAD), nonanal, strychnine, daptomycin, but also free fatty acids, oxylipins, sphingolipids, and acylcarnitines. A big thank you to all the contributors! Make sure to let them know that you share their passion for their favorite metabolite by connecting with them with the links below.2022-07-0533 minMentes CovalentesMentes CovalentesBebidas energéticas: ¿dan alas? #48En el episodio de hoy Hugo y Clara hablan de las bebidas energéticas: historia, composición y efectos ¿De verdad dan alas? ¿Son peligrosas para la salud? Notas:Redes sociales:Puedes seguirnos en Twitter, Instagram y Facebook para estar al tanto de cualquier novedad.Si quieres aprender más sobre Neurociencia, puedes seguir a Clara en su canal de YouTube “Cerebrotes”, donde sube vídeos semanales hablando de Neurociencia y Psicología. También la puedes encontrar en Twitter, Instagram y Facebook con el nombre artístico de Cerebrotes. A Hugo sólo pue...2022-06-161h 02The Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Julie CourraudStudy design & metabolomics in the clinics Julie Courraud Researcher in clinical metabolomics, National and Kapodistrian University of Athens, Greece Current affiliation TrAMS group Athens Previous affiliation Statens Serum Institute Copenhagen Discussed paper by Courraud et. al. Studying Autism Using Untargeted Metabolomics in Newborn Screening Samples More about The Metabolomist podcast2022-06-0759 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - What it is aboutWelcome to this new podcast Dr. Alice Limonciel Senior Scientist | Data Interpretation at biocrates life sciences ag. Favorite metabolite Asymmetric dimethylarginine (ADMA) Connecting ideas to improve our understanding of biology; that’s what data interpretation is about. In the episodes of this podcast I host, I put each metabolomist’s story in the spotlight to expand our metabolomics interpretation toolbox. My background is in molecular toxicology, with a strong focus on omics analysis and integration. Today, I use these skills to tell the stories that twinkle in the depths of meta...2022-05-0303 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Jan KrumsiekSex differences in metabolomics & AI-based networks Jan Krumsiek Assistant professor at the Institute for Computational Biomedicine, Weill Cornell Medicine, New York Krumsiek lab @Cornell Favorite metabolite 2-Hydroxyglutarate Discussed paper by Krumsiek et. al. Gender-specific pathway differences in the human serum metabolome Getting started with Gaussian graphical models (GGMs) MoDentify R package Modular metabolomics pipeline maplet R toolbox Open access multi-omic tools discussed (from other groups) Multi-omics factor analysis (MOFA) OmicsAnalyst Other resources Krumsiek lab github repository More...2022-05-0346 minThe Metabolomist podcastThe Metabolomist podcastThe Metabolomist - Gabi KastenmüllerData sharing & stratification in metabolomics Dr. Gabi Kastenmüller Group leader Metabolomics at the Institute of Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum München, Germany (since 2011) Kastenmueller group @Helmholtz Favorite metabolite b-citryl-L-glutamate Discussed paper by Arnold et. al. Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome Database links discussed AD Atlas Omicscience Snipa GWAS Server Other resources Talk about the Omicscience platform by Prof. Claudia Langenberg (given at the biocrates Pan-Cohort Metabolomics event 2021) 2022-04-2043 min