Shows
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 27: Groundhog Day, The Ice Palace, and $25 Trillion Cancer CostsMedBuzz:
Watch now as Dr Marshall discusses the growing instability at the FDA, including job cuts, leadership turnover, and structural reorganization.
Main Topic:
This episode of Oncology Unscripted explores the projected $25 trillion global cost of cancer care, rising cancer incidence, and declining mortality, all set against political and funding uncertainty in frozen Washington, DC.
Interview:
In this episode of Oncology Unscripted, John Marshall, MD, sits down with Richard Pazdur, MD, former director of the FDA’s Oncology Center of Excellence, for a candid discussion about his transition to and from the FDA, reflecting on what’s been built and what is a...
2026-02-2333 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 26: Microbes, Mutagens, and Mortality: CRC in a Younger GenerationOncology Unscripted at ASCO GI: People, Pipelines, and PrecisionJohn Marshall, MD:Hello, everybody, from San Francisco, California. My name is Dr. John Marshall, and you are on—maybe unwisely—Oncology Unscripted. But thanks for joining me. I love this meeting, but let's first talk about the news of 2026.Top of the line is: we're out to get new countries. Now, I'm sort of running for mayor of Havana. I don't know if it's important that I, in fact, speak Spanish—because I don't. I speak a little bit of French. My Spanish is terrib...
2026-01-2833 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 25: New Hope in GI Cancer CareMedBuzzTariffs, Taxes, and Trade-Offs: Can Raising Taxes in the UK Get You Cheaper Drugs in the US?John Marshall, MD: John Marshall for Oncology Unscripted. There's been all sorts of stuff going on out there in healthcare—in the business of healthcare—and a recent article that was just published in The New York Times told us something about the relationship between the National Health Service, how patients get access to drugs there in Great Britain, and our relationship with them and the tariffs. You're like, how could the tariffs have anything to do with the...
2025-12-1822 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 24: How Do We Translate MRD Innovation Into Everyday Oncology Practice?MedBuzz: From Hormones to Heroines: Couric, Cancer, and the Case for ChangeJohn Marshall, MDHello, everybody. John Marshall for Oncology Unscripted, coming to you from my now almost empty office. I've been in this office for, gosh, 20-plus years. It's the big office. You may or may not know I stepped down as the division chief here at Georgetown. We planned it—I wanted to do it a while ago. They said no. So, I finally got to step down because I wanted to do some other things. I get a lot of time back fr...
2025-12-1523 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 23: The Molecular Space Race: Will It Bring Earlier Detection and Better Treatment?MEDBUZZ [0:00:05]When the Sources of Trusted Information Change—Who Do We Believe?John Marshall, MD:Happy whatever day it is today when you're watching this. John Marshall for Oncology Unscripted. A little bit of a rainy day here in Washington, DC. It's been a little bit of a weird time here in Washington, DC—even weirder than it normally has been.Let's start with a little of the business of our world today—the business of oncology. You may have seen that we have a new National Cancer Institute director: Dr Anthony. Profes...
2025-11-1833 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 22: ESMO, Efficiency, and Evidence: A Look Ahead at New Data and Important Updates[00:00:05] Main Topic ESMO, Efficiency, and Evidence: New Data, China’s Science Leap, and Leucovorin and Autism John Marshall, MD: Hey everybody, John Marshall from Oncology Unscripted. There is so much going on right now that we're gonna need a full hour-long show, but we're not gonna do that to you. We still promise short bites here and there of the stuff that's going on, just to make sure you're in the loop. I'm sure you are.But let's start with a little science. And the science we wanna focus on is the upcoming ESMO...
2025-10-1433 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 21: Watching Vaccine Access Collapse in Real Time[00:00:05] MedBuzz: Back to Being ‘Just a Doctor’John Marshall, MD: John Marshall for Oncology Unscripted, coming to you live from this big office. This is the biggest office because, you know, I've been the Chief of the Division here at Georgetown for 20 years. I didn't want the job when I was first offered it a long time ago. I ended up saying yes. Of course, that's a dramatic change in one's academic career—taking on administrative roles like this. You do get the big office, which is nice, but you also get a lot of other stuff. You kn...
2025-09-1620 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 20: Why Are More Healthy Young Adults Getting GI Cancer?Why Are More Healthy Young Adults Getting GI Cancer?[00:05]John Marshall, MD:John Marshall for Oncology Unscripted. Big paper coming out of _JAMA_—it's actually a review article. Really, really smart people and friends up in Boston looked at this. We all see it: this emerging trend of younger and younger people getting all kinds of cancer. This particular paper wasn’t about all kinds of cancer, but we’re clearly seeing it in GI cancers. We don’t really understand what’s going on, but we see it—it’s impacting our clinic. Maybe it was f...
2025-08-2038 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 19: Who Really Benefits From Cancer Innovation—and How Can We Do Better?ACCESS THROUGH INNOVATION: THE POWER OF SMARTER CANCER CARE STRATEGIES[00:00:05] John Marshall, MD: John Marshall for Oncology Unscripted. Really no script at all, but we are post-ASCO here in Washington, DC, trying to take all of those major innovations that we all get so excited about—curves with big deltas that we saw in all sorts of different cancers, including the humblest of them all: GI cancers.So, now the question is: how do you take those innovations and those changes—some of them are added to NCCN, some of them may be FDA-approved, some of t...
2025-07-1555 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 18: “Badge-up” with Dr Marshall at ASCO 2025“Badge-up” with Dr Marshall at ASCO 2025John Marshall, MD: John Marshall coming to you live Oncology Unscripted, not from my office back in Georgetown, but from beautiful downtown Chicago, Illinois at ASCO 2025. Look at this amazing place. 40,000 of our closest friends.To get in, you need to have one of these. So, I'm gonna go ahead and badge up. I got a fancy red collar thing here, boy, that makes me stand out even that much more.But what we're gonna talk about today first is the social aspect. You remember in anticipation of c...
2025-06-1011 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 17: Badges, Booths, and Buses: Welcome to ASCO 2025Badges, Booths, and Buses: Welcome to ASCO 2025John Marshall, MD: John Marshall Oncology Unscripted. You know what this is? Yeah. You know what this is. This is my ASCO badge. It is that time of year again where I. I don't know, 40, 50, 60,000 of us and our closest friends all fly up to Chicago, stay in hotels that are overpriced, get bused around downtown Chicago, even on Saturday and Sunday. We get in nice clothes. We go to the convention center. We probably share a virus or two, but we mostly share important new information around the world...
2025-05-2832 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 16: No Evidence of Disease—No Need for the Knife?No Evidence of Disease—No Need for the Knife?John Marshall, MD: John Marshall for Oncology Unscripted. Let's talk a little science and cancer medicine. I’m gonna come at you from a little bit of a different angle. Yep. A GI cancer angle, but a little bit different.We have long felt in order to cure GI cancers, we had to do surgery, that it was the only way to ultimately cure people. But we all know that when we do neoadjuvant something could be chemo chemoradiation. we operate. A certain sub portion of the...
2025-05-1234 min
Decera Clinical Education Medical Specialties PodcastQuality Improvement in Obesity Care: How to Implement Virtual Support GroupsListen in as Joseph Kim, MD, MPH, MBA, interviews Sejal Desai, MD, DABOM, to learn about how she implemented virtual support groups to improve obesity care at her practice, including:Dedicating 5 support groups with chat features to obesity-specific topics (eg, sleep, nonscale wins)Moderating these chats to ensure no misinformation is shared and a positive, safe space is maintainedExpanding to include other virtual options that allow patients to engage more in their careUtilizing free and subscription-based services to aid in marketing effortsSharing lessons learned for those interested in implementing similar virtual options for their patients Presenters
2025-05-0727 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 15: We Funded the Cure—Now We're Pulling the Plug?We Funded the Cure—Now We're Pulling the Plug?John Marshall: Welcome to Washington DC. My name is John Marshall. This is Oncology Unscripted. There is a whole lot of stuff going on out there, seemingly unscripted, seemingly without much in the way of a sense of motivation, really a plan. It's just blow it up. Let's see what'll happen after the fact. But let's stop for just a second and think about what science, federally funded science, has accomplished over the last many decades here. Because a lot of us, including a lot of the...
2025-04-1626 min
Decera Clinical Education Medical Specialties PodcastQuality Improvement in Obesity Care: How to Implement Documentation ShortcutsListen in as Joseph Kim, MD, MPH, MBA, interviews Sophia Kwon, MD, to learn about how she implemented a documentation shortcut at her institution to improve obesity care, including:Creating an obesity checklist within the electronic health recordTraining staff to correctly use this checklist and broach obesity topics with patientsGarnering feedback to ensure this checklist did not add to note fatigue or burnout among staffSharing lessons learned for others interested in implementing a similar documentation shortcutPresenterJoseph Kim, MD, MPH, MBAPresidentQ Synthesis, LLCNewtown, Pennsylvania Sophia Kwon, MD
2025-04-1124 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 14: The Gender Gap in Genius: Why Credit Still Isn’t EqualPublished, Performed, Passed Over—Because Science Still Has a Gender Problem[00:00:05]John Marshall, MD: John Marshall, Oncology Unscripted. It's unscripted because you can't make this stuff up. I don't know if your week or the last two has been anything like mine, but our country and our science and healthcare, and all of that stuff, is really undergoing an incredible number of changes so quickly that we can't even catch up with what the impact will be. And maybe It's only because we're in health care, but I gotta believe that the impact that all of...
2025-03-2643 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 6: The Weight of The White Coat: Battling BurnoutTHE WEIGHT OF THE WHITE COAT: BATTLING BURNOUTHow Do Middlemen Impact Our Practices? [00:00:00]John Marshall, MD: Welcome back everybody to Oncology Unscripted. It is August and if you're lucky like I am, August is vacation time for me. I am at this beautiful place somewhere in the south, somewhere near a golf course and an ocean; a little river flowing right over there, some egrets and an occasional pelican flying by. There are fruity rum drinks, most evenings, which makes for a very pleasant time away from work. So, I'm on vacation, and I...
2025-02-2015 minOncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 5: PBMs—The Middlemen Shaping Treatments and CostsJohn Marshall, MD: Hey, everybody. John Marshall with Oncology Update. Welcome back. This is episode 5. We now have a really cool function called ask a question. Click on that. Send us something. We hope to get back with you with an answer.Most of the time, you know, you see these things and it's all nailed down, and you know exactly what you're about to get. Not so much with this. We’re really trying to bring to you the current days news. What's going on in our world in the world of cancer, both in...
2025-02-2040 minOncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 4: What's The Truth in Oncology?[00:00:00]John Marshall, MD: Hey everybody, this is, believe it or not, episode four of Oncology Update, where we're really trying to get to, God should we say it, the truth in oncology. There's so much going on out there. It's a complex business. There's a lot of really cool science. There's a lot of progress going on. We're affecting a lot of people's lives, including our own. So, let's jump right in and see what's going on out there this week. Remembering the Father of Tamoxifen[00:00:31] I don't know if you sa...
2025-02-2027 minOncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 3: How Do You Stay Up To Date?Oncology Update: Introduction [00:00:00]John Marshall, MD: Welcome back to Oncology Update. My name is John Marshall here from Georgetown University, Washington, D. C., the land of freedom. I don't know what it is the land of anymore, but welcome back to Episode 3 of Oncology Update. Our theme for this session is going to be, how do you stay up to date? How do your patients stay up to date with all that's going on in the world of oncology? And are you, in fact, delivering state-of-the-art treatment? Or are you, in fact, maybe delivering something, s...
2025-02-2035 minOncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 2: Why is Cancer so Expensive? With Special Guest Dr. Laura EssermanJohn Marshall, MD: Hey everybody, John Marshall for Oncology Update. Believe it or not, second episode. They let me do a second one. There's bad judgment on their part.ASCO Buzz[00:00:13]We're just back from ASCO, so you know how everybody's doing. You're still trying to pile out of your emails and figure out if you're actually going to get reimbursed for that dinner or not try for it. You never know. It might work out. Let's start and kind of reflect a bit on this meeting, that is ASCO. You k...
2025-02-2027 minOncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 1: Oncology News, ASCO Plenaries, and RVUs[00:00:00] John Marshall, MD: Hey, everybody out there. This is John Marshall live from my office at Georgetown University. And this is oncology update for May 22, 2024. We're about one week out from ASCO. There's a lot going on, but first let's talk a little bit about what's going on out there in our business world in oncology today.Shifts & Shocks: Layoffs, Dose Reductions, and Drug Withdrawals[00:00:27] There’s been a crazy lot of stuff happening. First, I don't know if you saw this, but Bayer laid off a thousand plus people or will do that over th...
2025-02-2020 minOncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 7: Too Complex, Too Costly: Are CROs Draining Clinical Trials?[00:00:05]John Marshall, MD:Hey, everybody, John Marshall back for oncology unscripted. If you've been silly enough to further away your time with me, we're now on the 7th episode, believe it or not. Goodness gracious, the sponsors of this are crazy to let me keep going. But we do have some really cool stuff to talk about today, and I hope you'll listen in as I review not only sort of what's going on in our world, a little bit of gossip, a little bit of business, we're going to talk about the l...
2025-02-2039 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 13: From Science to Survival: Dr Marshall Sounds the Alarm on the Dangerous Freeze on Cancer Research[00:00:05] John Marshall, MDHello, everybody. John Marshall from Oncology Unscripted. Do you know where I was this past weekend? I was in San Francisco. It's actually pretty nice weather there in San Francisco. I go pretty much every year. In fact, I have gone to every GI ASCO. Skipping This Test in Frontline Metastatic Colon Cancer? That’s Malpractice.[00:00:24] It's really usually my first business trip of the year. Usually, the weather out in San Francisco is kind of rainy and gloomy in the fifties, but it was pretty sunny compared to here out...
2025-02-1417 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 12: The Economics of Cancer Care: Who Pays for Progress?The Economics of Cancer Care: Who Pays for Progress? John Marshall, MD: What do you guys think? What do you think I'm looking like today here in Washington D.C. In January 2025? Well, What I'm trying to look like is the new administration, which is moving in just down the street from me there. There is an unfortunate casket, a hundred-year-old man inside, draped in the American flag. What I think of as a sort of heroic politician. And in a couple of weeks, we're going to have a parade here for next wave of po...
2025-01-2427 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 11: What’s Making the Impossible Possible in Pancreatic Cancer?MedBuzz: The PBM Pushback[00:00:00]John Marshall, MD: Ho, Ho, Ho, everybody out there. This is John Marshall for Oncology Unscripted, and we're going to talk a lot about pancreatic cancer today. We're also going to talk about some other things as well, but I thought I would sort of start off with a little holiday story. See that stocking? I've had this stocking for a long, long time. I actually keep it right over there in my drawer, and it's a reminder of what we do for a living. So, a patient almost 30 y...
2025-01-0226 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 10: Is the Inflation Reduction Act a Threat or Opportunity for Oncology?[00:00:00]Is the Inflation Reduction Act a Threat or Opportunity for Oncology? [00:00:05][00:00:05] John Marshall, MD: Hey everybody, John Marshall live from Washington DC where all the action is happening. A lot of moving vans are likely to be coming here soon as the new party comes in to take over maybe everything. We're going to have to see how that goes. We're all living in this crazy state of uncertainty about just how much. Are they saying is going to happen? But we'll see. That's our future. [00:00:34] But what I really want to...
2025-01-0232 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 9: Are You Overdosing Your Patients?Monopoly Concerns with Oncology Acquisitions: Should We Be Worried [00:00:05] John Marshall, MD: John Marshall, MD: Hey, everybody, John Marshall with Oncology Unscripted, even though I've got a little bit of a script right here, but don't tell anybody. Today, we're going to talk all about dosing of medicine, and do we have it right or not, particularly with some of our newer cancer medicines. And I'm going to really drill down on a couple that I know a lot about that I hope you will use in your own practice, quite honestly, and make your life a l...
2024-11-1429 min
Oncology Unscripted With John MarshallOncology Unscripted With John Marshall: Episode 8 :Gut Feeling: Is Our Microbiome the Key to Better Cancer Care? Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
2024-11-1331 min
Decera Clinical Education Medical Specialties PodcastThe Art of Multidisciplinary Care for Patients With Metabolic Dysfunction–Associated SteatohepatitisIn this episode, Arun B. Jesudian, MD, and Mazen Noureddin, MD, MHSc, discuss the expert-informed clinical pathway for the multidisciplinary care of patients with MASLD or MASH, current and emerging therapeutics, and management optimization strategies. Presenters:Arun B. Jesudian, MDAssociate Professor of Clinical MedicineDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew York, New YorkMazen Noureddin, MD, MHScProfessor of MedicineHouston Methodist HospitalDirector Houston Research InstituteHouston, TexasContent based on an online CME program supported by in...
2024-03-1329 min
Decera Clinical Education APP PodcastThe Art of Multidisciplinary Care for Patients With Metabolic Dysfunction–Associated SteatohepatitisIn this episode, Arun B. Jesudian, MD, and Mazen Noureddin, MD, MHSc, discuss the expert-informed clinical pathway for the multidisciplinary care of patients with MASLD or MASH, current and emerging therapeutics, and management optimization strategies. Presenters:Arun B. Jesudian, MDAssociate Professor of Clinical MedicineDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew York, New YorkMazen Noureddin, MD, MHScProfessor of MedicineHouston Methodist HospitalDirector Houston Research InstituteHouston, TexasContent based on an online CME program supported by in...
2024-03-1329 min
Decera Clinical Education Infectious Disease PodcastDTR-Pseudomonas aeruginosa: Applying Best Practices in Complex Clinical ScenariosIn this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving Pseudomonas aeruginosa with difficult-to-treat resistance, including: Mechanisms of β-lactam resistanceEffect of resistance mechanism on susceptibility to antipseudomonal agent2023 IDSA guidance recommendations Activity against newer antipseudomonal β-lactams in the United StatesThe latest clinical data by antimicrobial regimen: - Ceftolozane/tazobactam - Ceftazidime/avibactam - Imipenem/cilastatin/relebactam - CefiderocolApplying antimicrobial stewardship principlesProgram Director:Trevor Van Schooneveld, MD, FSHEA, FACP Professor, Division of Infectious DiseasesProgram...
2023-11-1617 min
Decera Clinical Education Infectious Disease PodcastWhat Challenges and Opportunities Exist With Implementation of Available Long-Acting ART?In this episode, Iskandar Azwa, MBChB, MRCP; Nikos Dedes; Beng Eu, MBBS; Bernadette Sharp; and Jeff Taylor discuss challenges and opportunities with long-acting ART implementation, including:Personal experiences with receiving LA ART Views on long-acting ART in the development pipelinePerspectives on self-administration of LA ARTPresenters:Iskandar Azwa, MBChB, MRCPAssociate ProfessorInfectious DiseasesFaculty of MedicineUniversity of MalayaKuala Lumpur, MalaysiaNikos DedesPositive VoiceAthens, GreeceBeng Eu, MBBSDoctorPrahran Market Clinic Melbourne, Victoria, AustraliaBe...
2023-09-1113 min
Decera Clinical Education Infectious Disease PodcastWhat Patients Want in HIV Treatment and Prevention: United KingdomIn this episode, Marc Thompson and Tristan J. Barber, MA, MD, FRCP, discuss some of the barriers to genuinely patient-centered HIV care in the United Kingdom and offer calls to action for healthcare professionals for responding to patient preferences. They discuss barriers to HIV testing and effectively communicating the benefits of testing to disparate communities. They also talk through the difficulties in maintaining patient engagement in HIV care and the value of using peer support workers in HIV clinics. You will then hear Marc and Dr Barber talk through treatment and prevention practices. They focus on the importance of...
2022-11-0244 min
Decera Clinical Education Oncology PodcastCongress to Clinic: Post-ELCC Updates on Antibody–Drug Conjugates in NSCLCIn this episode,Egbert F. Smit, MD, PhD; David Planchard, MD, PhD; and Helena A. Yu, MD, answer audience questions from a live webinar regarding clinical data on antibody–drug conjugates in NSCLC including:Biopsies and biomarker testing considerationsTumor heterogeneity and targeting of brain metastasesLiquid biopsiesSequencing of ADCs following previous therapyToxicity managementPresenters:Egbert F. Smit, MD, PhDProfessorDepartment of Pulmonary DiseasesLeiden University Medical CenterLeiden, NetherlandsDepartment of Thoracic OncologyNetherlands Cancer InstituteAmsterdam, NetherlandsDavid Planchard, MD, PhDHead of Thoracic Gro...
2021-05-1824 min