Shows
2025-11-1207 min
The Insight is Capital™ PodcastCRM3 (TCR) - More than compliance - It's a chance to define your valueCRM3 (Total Cost Reporting) isn’t just another compliance box to check—it’s the biggest shift in cost transparency Canadian advisors have ever faced, and how you handle it could define your client relationships for years to come.In this episode of Insight is Capital, host Pierre Daillie sits down with three leading voices to unpack the realities—and the opportunities—of Total Cost Reporting (TCR/CRM3).Joining the conversation are:Arnie Hochman, Senior Vice President & General Counsel at SIMADr. David Lewis, Behavioural Scientist, Consultant & Independent DirectorSteve Braugiroux, Associate Vice President, Dealer Relations at National BankTogether, they break down...
2025-08-2733 minInsight is Capital™ PodcastCRM3 (TCR) - More than compliance - It's a chance to define your valueCRM3 (Total Cost Reporting) isn’t just another compliance box to check—it’s the biggest shift in cost transparency Canadian advisors have ever faced, and how you handle it could define your client relationships for years to come.In this episode of Insight is Capital, host Pierre Daillie sits down with three leading voices to unpack the realities—and the opportunities—of Total Cost Reporting (TCR/CRM3).Joining the conversation are:Arnie Hochman, Senior Vice President & General Counsel at SIMADr. David Lewis, Behavioural Scientist, Consultant & Independent DirectorSteve Braugiroux, Associate Vice President, Dealer Relations at National BankTogether, they break down...
2025-08-2733 min
On AIRR - Immune receptors in the clinicOn AIRR 18: From single-chain TCR sequencing to paired high-throughput methods with Paul ThomasIn this episode of On AIRR, Dr. Paul Thomas, reviews advances in the field of TCR sequencing. Dr. Thomas is a faculty member in the Department of Immunology of St. Jude Children’s Research Hospital. His work has advanced our understanding of innate and adaptive immune responses and TCR specificity with a focus on responses to viral infections.
In Episode 18 of On AIRR, Dr. Thomas shares his journey from immunoparasitology to pioneering TCR repertoire sequencing. He began his scientific career studying innate immune responses to parasites during his graduate work in immunoparasitology. Motivated by a desire to us...
2025-06-0946 min
Beyond Biotech - the podcast from LabiotechTCR-NK: A novel cell therapy transforming cancer treatmentAre TCR-NK treatments the next big thing in cell therapies for cancer patients?As biotechs and pharma companies continue to innovate to address patient needs in oncology, T-cell receptor therapies, or TCR-Ts, are attracting significant interest and investment. There are already some promising results for TCR-Ts tackling solid tumors – but one Norwegian biotech is taking a slightly different track.This week, we sit down with Namir Hassan, CEO of Zelluna, a company with a mission to eliminate solid cancers by pioneering the development of T cell receptor guided natural killer, or TCR-NK, cell th...
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S&S On Biotech3.9 The slow rise of TCR-T therapyWhen the first chimeric antigen receptor T-cell (CAR-T) therapy was approved in 2017, there was a general expectation that T-cell receptor T-cell (TCR-T) therapies would follow shortly afterwards and would greatly expand the range of addressable antigens. Despite considerable efforts, CAR-T therapies are still limited to haematological cancers expressing extracellular antigens, such as CD19 or B-cell maturation antigen (BCMA). Autologous TCR-T therapies can be engineered to target intracellular as well as extracellular peptide antigens presented on the cell surface by human leukocyte antigens (HLAs) and can be more readily used in solid tumors as well as in haematological c...
2024-07-2936 min
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Science SocietyUnmasking Leukemia: The Role of MHC:TCR Signaling with Dr. LaffeyThis episode delves into the cutting-edge research of Dr. Laffey, who has been investigating the role of Major Histocompatibility Complex:T cell antigen receptor (MHC:TCR) signaling in the development of T cell tumors. While this signaling pathway is crucial for T cell development and immune responses, it can also trigger the formation of T cell tumors under abnormal conditions.Dr. Laffey's research focuses on a low-frequency progenitor cell population known as Early αβ TCR+ Double-Negative (EADN) cells. Present in both mice and humans, these cells can transform into thymic leukemia. His work has shown that EADN cells do...
2022-09-091h 47
tcr! diaries - podcastBack to regular life
content: Apr 19, 2019 · podcast: Jul 21, 2022
Audio (MP3): 20190419 - Back to regular life
Do you know what I really hate?
When somebody is being over-the-top nice after they’ve fucked something up.
Do you know what I really like?
When someone offers up a sincere apology and then gets on with the day.
Own it. Regret it. Forget it.
Take five minutes, have a real conversation, and then go back to regular life.
If I don’t acknowledge I can come across like an unsym...
2022-07-2100 min
The Creature ReportTCR_VPAL-ARCHIVAL_RECORDING_1023_SUBJECT1733CHARLES_SUBJECT964ADDISON_MISSINGSee you next week, Anchor.
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2021-10-2408 min
tcr! diaries - podcastI only fought with the police once
content: Aug 22, 2018 · podcast: Sep 8, 2021
Audio (MP3): 20180822 - I only fought with the police once
I only fought with the police once and there was only one of them. And it was 3 in the afternoon. And I was drunk and feisty. And then he tackled my 19 year old self in an alley and one side of my face ended up in some gravel. And then I went to jail with a swollen eye. And got to spend the rest of the evening sobering up.
About 9pm or so and no longer drunk, I d...
2021-09-0900 min
The Creature ReportTCR-VPAL_26_AdditionalNotesThe Creature Report Documentation & Archival Assistant!
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2021-08-1409 min
tcr! diaries - podcastMiracles are seen in light
content: Apr 27, 2018 · podcast: May 6, 2021
Audio (MP3): 20180427 - Miracles are seen in light
I fall short in life.
That’s not a judgment call or me being hard on myself. It just is. I’m just another guy wandering around aimlessly doing my best…and sometimes doing my least.
Struggling to maintain that non-mistake-making state only makes my life harder. Letting that struggle go gave me so much more free time to enjoy life and the company of my fellow humans.
Well, I guess I never really expecte...
2021-05-0600 min
The Cultural Reset (TCR)An Interview with DEMIE CAO - 'The Cultural Reset' | Artist Interview Series - Episode #16This week’s episode of The Cultural Reset’s Artist Interview Series sees TCR’s Nick Lee and Shay Ervin speaking to Chinese-American songwriter/performer Demie Cao aka ‘Demie The Destroyer’. In this discussion, Demie reflects on her career beginnings—from her stint in ballet and K-Pop to her current love of hip-hop and live performance—and her thoughts on the branding limitations put on AAPI artists navigating the music industry.
...
The Cultural Reset is a platform designed to uplift the voices of POC and LGBTQ+ artists through album reviews, artist interviews, and curated playlists. To see more of...
2021-05-0342 min
The Cultural Reset (TCR)An Interview with JASTIN ARTIS - 'The Cultural Reset' | Artist Interview Series - Episode #15In this newest entry of The Cultural Reset’s Artist Interview Series, TCR’s Nick Lee and Shay Ervin speak to DMV artist, Jastin Artis about his mission as an artist and his perspective on the expectations of artists in the music industry. From his thoughts on the industry’s treatment of genre-bending to his advice for all artists—both younger and mature—navigating the industry, Jastin shows the world his vision to reset the culture of music.
...
The Cultural Reset is a platform designed to uplift the voices of POC and LGBTQ+ artists through album revi...
2021-04-2252 min
The Cultural Reset (TCR)An Interview with ROB MURAT - 'The Cultural Reset' | Artist Interview Series - Episode #14This latest entry of The Cultural Reset’s Artist Interview Series sees TCR’s Nick Lee and Shay Ervin speak to musician and Netflix’s ‘On My Block’ actor, Rob Murat. In an especially thought-provoking discussion, Rob and the team break down the differences between “inclusion” in TV/Film vs. music and the importance of creating a lasting space for people of color in entertainment. From his perspective on ‘creative trailblazing’ to his advice on navigating creative industries, Rob’s conviction to maintaining his integrity shines through in this intimate conversation.
...
The Cultural Reset is a platform design...
2021-04-1437 min
tcr! diaries - podcastNobody can fuck with you
content: Feb 12, 2018 · podcast: Mar 24, 2021
Audio (MP3): 20180212 - Nobody can fuck with you
Remember that one time when you were younger? When nobody could fuck with you?
Because everything had fallen into place. Because all the dots connected. Maybe your best friend was there.
It doesn’t matter who you were with or how or when you got there. But that was it.
That was the moment when you rose above the bullshit and realized you were more than what you had always felt. It was like you...
2021-03-2400 min
The Cultural Reset (TCR)An Interview with FELISHA GEORGE-'The Cultural Reset' | Artist Interview SeriesContinuing our programming for Women’s History Month 2021, TCR’s Creator and Editor-in-Chief, Nick Lee, and Assistant Director, Shay Ervin, spoke with rapper and bonafide “Word Magician”, Felisha George. As an alum of Netflix’s Rhythm and Flow, Felisha George speaks about her experience on the show as well as her personal journey as a queer-female artist navigating the hip-hop genre. In an intimate discussion, George touches on the importance of control over one’s brand as a woman and her thoughts on the unrealistic standards placed on women in rap-music.
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2021-03-1944 min
The Cultural Reset (TCR)An Interview with TYLER SIMONE-'The Cultural Reset' | Artist Interview SeriesIn honor of Women’s History Month, this installment of The Cultural Reset’s Artist Interview Series sees TCR’s Nick Lee and Shay Ervin sit down with Tyler-Simone Molton, the lead singer of new wave/punk band Lesibu Grand. In an enlightening discussion, Tyler touches on the very personal inspiration behind her artistry as well as her dedication to authentic self-expression as a black woman in the music industry and her love of the unconventional.
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2021-03-0337 min
The Cultural Reset (TCR)An Interview with NIAMBI RA-'The Cultural Reset' | Artist Interview SeriesIn this newest installment of The Cultural Reset's Artist Interview series, Creator Nick Lee and Assistant Director, Shay Ervin, sit down with Afro-futurist rapper, singer/songwriter Niambi Ra. A queer, black woman navigating a music career in Hip-Hop, Niambi speaks to TCR on the importance of artistic mentorship for artists of color, how her creative instinct intertwines with social activism, and remaining a music change-maker despite industry pressures for conformity.
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2021-02-281h 14
The Cultural Reset (TCR)An Interview with MAYA J-'The Cultural Reset' | Artist Interview SeriesThe Cultural Reset kicks off Black History Month with an intimate interview with singer and actress Maya J. TCR’s Nick Lee and Shay Ervin sat down with Maya to discuss her new single ‘Trouble’ as well as her experience navigating the ups and downs of the entertainment industry as a female artist. From her unique perspectives on artist-label relationships to her pledge to always create outside of the box, Maya dishes on the importance of maintaining artistic integrity in an era of oversaturation in music.
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Support this podcast: https://anchor.fm/the-cultural-reset/support
2021-02-0345 min
The Cultural Reset (TCR)An Interview with MDL CHLD-'The Cultural Reset' | Artist Interview SeriesIn another eye-opening entry of The Cultural Reset’s Artist Interview Series, TCR’s Nick Lee and Shay Ervin, sat down with Artist/ASL Interpreter/Tarot Reader Chris Corsini, AKA MDL CHLD, to chat about music inclusivity for deaf audiences. In an incredibly compelling discussion, Chris opens up about his efforts to create art with deaf people in mind, his mission to revolutionize the industry for deaf music-lovers, and the industry disparities that exclude the deaf from fully enjoying live performances.
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2021-01-2746 min
The Cultural Reset (TCR)An Interview with MEL SEMÉ-'The Cultural Reset' | Artist Interview SeriesA former contestant on The Voice: Spain and a multi-talented, classically trained musician, The Cultural Reset's Artist Interview Series is pleased welcome Mel Semé to the roster. In a beautifully vulnerable interview, TCR's leads Nick Lee and Shay Ervin spoke with Mel about his childhood musical roots, the story of his mother's passing, his spontaneous artistic process and navigating the music industry as an independent artist.
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2021-01-1345 min
tcr! diaries - podcastSteam Locomotive Musical
content: Jan 11, 2021
Video (MP4): 20210111 - Steam Locomotive Musical
Audio (MP3): 20210111 - Steam Locomotive Musical
Here we have a 1930s steam locomotive with drums, an upright bass, a couple of pianos, and a string section. The original video was over 18 minutes long so I chopped and rearranged to fit the music I put together. I guess this is the kinda thing I do in a pandemic.
I had originally planned for the music to go with some winter driving footage but that didn’t pan out. When I came across Ne...
2021-01-1100 min
The Cultural Reset (TCR)An Interview with LEX-'The Cultural Reset' | Artist Interview SeriesThis empowering entry of The Cultural Reset's Artist Interview Series sees TCR heads Nick Lee and Shay Ervin speaking with genre-bending vocalist and musician, LEX. In a beautifully revealing interview, LEX speaks about the intention behind her newest album release 'Bits and Pieces' and the personal tragedy that inspires her on her path toward self-actualization and awareness.
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Support this podcast: https://anchor.fm/the-cultural-reset/support
2021-01-0945 min
tcr! diaries - podcastHouse Burning in Black and White
content: Dec 30, 2020 · podcast: Jan 1, 2021
Audio (MP3): 20201229 - House Burning in Black and White
Video (MP4): 20201229 - House Burning in Black and White
A few piano melodies while a house burns in black and white 🎹🔥🏠
Reminds me of the lower end of the Peanuts theme in certain parts.
#diariespodcast #diariesvideo
JFK Clone High
· Dec 30, 2020 at 4:44 pm
Hey is it okay if I use this video on my channel? It’s gonna be the same thing but a different shade
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2021-01-0100 min
tcr! diaries - podcastPandemic Violins
content: Dec 26, 2020
Video (MP4): 20201226 - Pandemic Violins
Audio (MP3): 20201226 - Pandemic Violins
It's winter in a pandemic. It's Christmas time. I'm on vacation. I sit and write and record music. After listening to The Beatles sing about Eleanor Rigby on a two hour loop, I got hooked on violins stabbing and stomping about. The music sounds best with headphones.
Nothing happens in the video. I needed something visual because most of the social medias don't do just audio. The footage is public domain and fairly boring.
🎶🎻 #diariespodcast #diarie...
2020-12-2700 min
The Cultural Reset (TCR)An Interview with SHENNA-'The Cultural Reset' | Artist Interview SeriesA new addition to The Cultural Reset's Artist Interview Series, indie-pop sensation Shenna sits down with TCR's Nick Lee and Shay Ervin for a lively discussion of her career journey. From moving to NYC at the age of 17 to reinventing the pop genre for women of color, Shenna gives TCR an in-depth rundown of how she is unapologetically breaking down barriers in music.
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2020-12-1237 min
The Cultural Reset (TCR)An Interview with ARIA WUNDERLAND-'The Cultural Reset' | Artist Interview SeriesThis week's entry of The Cultural Reset's Artist Interview series sees Nick Lee and Shay Ervin sit down with Alternative-Pop revolutionary Aria Wunderland. Aria joins TCR to discuss how quarantine has shaped her music-making process, the industry stereotypes used to stifle creatives, and how independent artists are working to reset the music industry's landscape.
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2020-12-0544 min
tcr! diaries - podcastBirds with piano
content: Nov 27, 2020
Audio (MP3): 20201127 - Birds with piano
Video (MP4): 20201127 - Birds with piano
If you need to relax after your Black Friday, please enjoy a little piano and birds in my bird bath. Being November in Illinois the birds won't get to do this much longer.
#diariespodcast #diariesvideo #naturerocks 🎹 🔊
alps
· Nov 27, 2020 at 8:26 pm
I’ve been getting 3 kinds of woodpeckers going to my feeder then bluejays, and cards. I could watch all day. 💯
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2020-11-2800 min
The Cultural Reset (TCR)An Interview with JAZZY MEJIA-'The Cultural Reset' | Artist Interview SeriesThis installation of The Cultural Reset's Artist Interview Series turns its focus to Pop/R&B singer/producer Jazzy Mejia. A teen icon and former member of internationally renown girl-group G.R.L., Jazzy Mejia sat down with TCR's Nick Lee and Shay Ervin to discuss her complicated transition from girl-group stardom to independent artist, the loved ones that inspire her creative process and growing up in and navigating the music industry as a woman of color.
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2020-11-2142 min
The Cultural Reset (TCR)An Interview with NADIA TEHRAN-'The Cultural Reset' Artist Interview SeriesIn a new, particularly intimate entry of The Cultural Reset's Artist Interview Series, TCR's Creator/EIC Nick Lee, and Assistant Director, Shannon (Shay) Ervin, sat down with Iranian-Swedish rapper and songwriter, Nadia Tehran. Known for the personal and political themes that govern her work, Nadia joins TCR to deconstruct her most-recent album 'Dozakh: All Lovers Hell' as well as discuss her artistic inspiration, her creative paths, and her experience as a woman of color navigating the injustices of the music industry.
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2020-11-1429 min
tcr! diaries - podcastSlow Mo Milkweed
content: Nov 9, 2020
Video (MP4): 20201108 - Slow Mo Milkweed
Audio (MP3): 20201108 - Slow Mo Milkweed
On weekends when I don't have Maggie I often pretend like I'm a cinematographer who knows how to play the piano.
I also had Milkweed seeds all over my face when I was done.
🎹 🎥 #diariespodcast #diariesvideo
gracey
· Nov 9, 2020 at 3:00 pm
That was beautiful
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tcr!
· Nov 9, 2020 at 3:11 pm
thank you so much!
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2020-11-0900 min
tcr! diaries - podcastRainy day bug ride
content: Oct 28, 2020
Video (MP4): 20201018 - Rainy day bug ride
In their downtime some people like to watch sports. Some people like to sew. Some people like to forage for frogs while frolicking in the forest. I like to pretend I’m a medieval composer while Maggie puts on her cinematographer cap and we’re driving around town in the sprinkling rain.
#diariespodcast #diariesvideo #maggie
jimi hindrance experience
· Oct 28, 2020 at 2:06 pm
Liked it. Holy Guacamole that’s a sweet bug!
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2020-10-2800 min
tcr! diaries - podcastBreak On Through by The Doors
content: Dec 1, 2017 · podcast: Aug 14, 2020
Audio (MP3): 20171201 - Break On Through by The Doors
https://www.youtube.com/watch?v=rOpQjD-rX0g
Peeps, here’s your the-gate-is-straight Friday jam.
Listening to The Doors when I was 9 and 10 opened up my musical world so much more than bands like the Beatles did. Don’t get me wrong, I love yellow submarines as much as the next u-boat commander but I met the darkly cool poet persona in songs like The End and Waiting for the Sun. I became all too familiar with the torture of lo...
2020-08-1400 min
tcr! diaries - podcastSmelling like coffee and Captain Morgan
content: Jul 6, 2017 · podcast: Jul 30, 2020
Audio (MP3): 20170706 - Smelling like coffee and Captain Morgan
One time I was driving to work on a hot summer morning. Just like today. Hung over pretty bad and nursing a pint of rum. I was in complete agony, had a fiery headache, and starting to sweat because my truck didn't have air conditioning. Taking shots now and then while auto-piloting the blue Ranger along the river. I needed just enough liquor to bring my headache down to a manageable level so I could make it through until lunch.
2020-07-3000 min
tcr! diaries - podcastNo reason for me to be in a hurry
content: Aug 9, 2017 · podcast: Jul 26, 2020
Audio (MP3): 20170809 - No reason to be in a hurry
Sometimes I got something going on, something I’m burning too much daylight on, and I can’t figure it out. The path isn’t clear. The monkey chatter is as loud as it gets and I feel myself ratcheting up.
One time way back in high school I was struggling with a drawing. When I asked my art teacher for help she told me that I’d overworked it. And she was right, plain as day, clear as mud. I...
2020-07-2600 min
tcr! diaries - podcastVirtual Bunker Tour
content: May 17, 2020
Video (MP4): 20200517 - Virtual Bunker Tour
Please enjoy a view from the futon in the office bunker.
#diariesvideo #basement
jenkins_arts
· May 17, 2020 at 2:41 pm
Excellent!
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tcr!
· May 17, 2020 at 5:22 pm
Yes and no 😊
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jimi hindrance experience
· May 17, 2020 at 8:08 pm
The Hunker Bunker
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Uncle Timmy
· May 17, 2020 at 10:06 pm
2020-05-1700 min
tcr! diaries - podcast100 percent decent
content: May 2, 2019 · podcast: Apr 11, 2020
Audio (MP3): 20190502 - 100 percent decent
You guys remember when Bill and Ted said, “be excellent to each other.”
I loved that line and that movie but being excellent all the time is hard. Like I’m driving and some fuckwad cuts me off, and then comes to a near complete stop when turning right. Excellence is the about the last thing in my fingertips.
Put them in the iron maiden 🤘
You guys know about washing machines and when they agitate clothes. I can feel a...
2020-04-1100 min
tcr! diaries - podcastDesperately Seeking Cup of Water
content: Sep 24, 2018 · podcast: Apr 5, 2020
Video (MP4): 20180924 - Desperately Seeking Cup of Water
Audio (MP3): 20180924 - Desperately Seeking Cup of Water
I would get one myself but I’ve just settled in for my late afternoon nap. I don’t need a full glass, a full cup will do. I know you’ve been there: partially parched and close to near death as your bones wither down to the marrow.
Plastic cups with the Millennium Falcon are preferred. Thor artwork will do. Toy Story cartoons are forbidden.
Pleas...
2020-04-0500 min
tcr! diaries - podcastsometimes you want something so bad
content: Sep 5, 2019 · podcast: Mar 27, 2020
Audio (MP3): 20190905 - sometimes you want something so bad
Video (MP4): 20190905 - sometimes you want something so bad
Peeps, you know how sometimes you want something so bad. Think about it day after day, get angry and frustrated because nothing changes… I get it. I’ve had my fair share of being stuck in jobs, relationships, stuck in some kind of mud.
But trust me when I say that good things are being sorted out in the background. Too often it takes a long mother-clucking time...
2020-03-2700 mintcr! diaries - podcastUnrelenting Happiness
content: Apr 15, 2012 · podcast: Mar 6, 2020
Audio (MP3): 20120415 - Unrelenting Happiness
Feelings need not always be put into words. They can just be felt, like tigers or butterflies, snake bites or feline purrs. After they're done (and even if they're not), open your heart to the love, to the glow of the Universe. It's there waiting and it's yours. It's your right, your entitlement and a perquisite to unrelenting happiness.
#lettherebehope #diariespodcast
tcr!
· Apr 15, 2012 at 11:01 am
Drinking from that cup embraces us with a power that withers all evil sp...
2020-03-0600 min
tcr! diaries - podcastNo horse blankets
content: Apr 10, 2019 · podcast: Jan 18, 2020
Audio (MP3): 20190410 - No horse blankets
When I got to the place where I couldn’t stand myself anymore, where I didn’t want to be the person I’d always been. And not do the same things I’d always done, I can see now that’s when I had reached the breaking point.
The pain of being me had broken my very soul. Fuck.
It wasn’t the drinking, it wasn’t ever the drugs. It was me. It wasn’t the traffic or the ot...
2020-01-1800 min
tcr! diaries - podcastA backlog of taxes
content: Nov 12, 2018 · podcast: Jan 12, 2020
Audio (MP3): 20181112 - A backlog of taxes
I spent the majority of my adult life either toiling around to get my head on straight or hiding in the shadows from the truth.
A backlog of taxes and overdue books.
Pull up a little bit farther at the red light because I don’t want to look at the dude next to me. It’s not that I didn’t wanna go to college. It’s just that my ship was listing and the captain was drunk...
2020-01-1200 min
tcr! diaries - podcastInwardly summiting a spiritual Mt Everest
content: Dec 29, 2019 · podcast: Jan 11, 2020
Audio (MP3): 20191229 - Inwardly summiting a spiritual Mt Everest
Seeking equality, fairness, the greater good...that does something remarkable for me. It breaks my selfish bubble. It makes me a whole human being. It gives me freedom.
But wait, there’s more. So much more. Seeking balance and harmony for all...brings me out of my despair. It brings light to my darkness. It brings healing to my pain. It lifts me up and out of feeling down and blue, up to the level of okay I w...
2020-01-1100 min
tcr! diaries - podcastdiaries for 2018 - book now available
content: Apr 29, 2019
Audio (MP3): 20190429 - diaries for 2018 - book now available
After all my moaning my 2018 diaries book is now ready to be put in your shopping carts. If you have an unfulfilled diaries magazine subscription don’t buy the book. Your paperback will be in the mail soon.
The ones available here on the site are autographed, too. Paperback and Kindle editions are available on Amazon, non-autographed of course.
You should buy my book. And then tell your friends about it. And share it on social media, as...
2019-04-2900 min
tcr! diaries - podcastPillsbury's Candy Apple frosting
content: Oct 14, 2018 · podcast: Apr 18, 2019
Audio (MP3): 20181014 - Pillsbury's Candy Apple frosting
Sometimes I’ll got out on a culinary limb. A daring yet delectable escapade, laying out loads of cash for adventurous taste combinations that send the conservatives repulsed to the bakeries of safety.
For example, in this year of 2018, this month of October, I dropped Candy Apple frosting from Pillsbury into my basket, impromptu style while in the aisles of Blue Goose. A one-handed yet non-acrobatic feat that impressed shoppers clear yonder to the western deli department.
Bas...
2019-04-1800 mintcr! diaries - podcastDo you ever wake up cranky for no good reason?
content: Sep 28, 2018 · podcast: Mar 14, 2019
Audio (MP3): 20180928 - Do you ever wake up cranky for no good reason?
And then when you’re walking down the stairs you say “fuck those guys” but there are no guys there?
And then when you’re standing in the kitchen getting your lunch ready you see a teeny purple flower on the floor and say “get the fuck out of here” and kick it under the stove?
And then Alexa plays Kiss Me Deadly and then you think to yourself “Why does Ozzy get to hold heaven...
2019-03-1400 min
Test & Code68: test && commit || revert (TCR) - Thomas DeniffelWith conventional TDD, you write a failing test, get it to pass, then refactor.
Then run the tests again to make sure your refactoring didn't break anything.
But what if it did break something?
Kent Beck has been recommending to commit your code to revision control after every green test run.
Oddmund Strømme suggested a symmetrical idea to go ahead and revert the code when a test fails.
Kent writes that he hated the idea, but had to try it.
Then wrote about it last September.
And now we have TCR, "(t...
2019-03-1338 min
tcr! diaries - podcasttcr! diaries podcast survey
content: Aug 24, 2018 · podcast: Jan 30, 2019
Audio (MP3): 20180824 - Podcast Survey
I’m interrupting the regularly scheduled episodes to announce a listener survey created by yours truly. It’s informal and there won’t be a test later. And I love your feedback!
It’s also quick and should take you less than 30 seconds.
Go now: tcrbang.com/form/podcast_survey/
On with the show.
#tcr #webdev #diariespodcast
Add a comment!
Got 30 seconds? Take the super duper, quick and easy podcast survey! Please. 😊...
2019-01-3000 mintcr! diaries - podcastShare the road with bikes?
content: Jun 14, 2018 · podcast: Dec 7, 2018
Audio (MP3): 20180614 - Share the road with bikes?
How about they go the speed limit? Or obey the traffic signals? Or decide if they’re going to be on the street or the sidewalk?
I ride my bike as much as anybody. Okay, that’s not true. I have a bike in my garage and I’ve only ridden a few times this year.
But I’ve seen the guy at Sammy’s Bikes race around town, blow through stop signs, make wild ass turns without warning, we...
2018-12-0700 mintcr! diaries - podcastA frantic game of animal tag
content: Jun 11, 2018 · podcast: Dec 2, 2018
Audio (MP3): 20180611 - A frantic game of animal tag
On this morning, the 11th of June I was greeted with a squeaky chipmunk in the basement just as I sat down with my first cup of coffee. It filled my heart with joy as the two H-Ks (hunter killers) and a lone chipmunk played a frantic game of animal tag.
A frenzied game of hide and seek if you will. Where if you lose needly claws hooked to hair trigger tendons pulled by honed muscles will rip into y...
2018-12-0200 min
CAR-TTCR engineeringWe have high qualified groups and advanced technologies to perform TCR engineering services covering every unit of manufacturing and delivery pipeline. From a tumor-reactive T cell or active anti-tumor T-cell antigens, the appropriate target sequence is introduced to modify T cells to target a broad range of tumors with improved specificity. With engineering TCR construction and a series of assay, such as transgene expression, TCR/CD3 stability, lymphocyte antigen reactivity and cytotoxicity, animal experiments, etc., we provide cGMP-compliant TCR products for preclinical and clinical trials. Learn more about TCR T cells. https://www.creative-biolabs.com/car-t/cellrapeutics-tcr-technology.htm
2018-11-2900 min
tcr! diaries - podcastSaturated, colorful clematis
content: May 18, 2018 · podcast: Nov 8, 2018
Audio (MP3): 20180518 - Saturated, colorful clematis
And on this 18th day of May nature said lettuce have more flowers, specifically the saturated, colorful clematis. And the peeps of the world drew in a beautiful breath and embraced the brilliance.
And then on a related note the man said, “If life is fleeting then that is irrelevant. In this minute let life’s focal point be the vibrancy.”
#photos #flowers #diariespodcast
jimi hindrance experience
· May 18, 2018 at 9:45 am
Holy shit, who is the a...
2018-11-0800 min
Il podcast di Motorsport Republic+Intervista Marcello Lotti: WTCR, E-TCR. La crescita inarrestabile del Turismo da corsaMarcello Lotti era il manager esecutivo del WTCC (il Campionato Mondiale Turismo). Circa cinque anni fa per una serie di manovre al vertice organizzativo della Categoria del Turismo lui esce di scena e si mette subito al lavoro su una idea di vettura nuova, su un nuovo regolamento. Obiettivo: rilanciare una specialità in crisi per costi e, quindi, partecipazioni. Tre anni fa lanciò il TCR e oggi, alla vigilia della quarta stagione, il TCR diventa lo standard mondiale della Categoria Turismo. Un successo inarrestabile che conta oltre 50 Paesi dove si corrono i Campionati Nazionali secondo la regola TCR e un Ca...
2018-03-3035 minIl podcast di Motorsport Republic+Intervista Marcello Lotti: WTCR, E-TCR. La crescita inarrestabile del Turismo da corsaMarcello Lotti era il manager esecutivo del WTCC (il Campionato Mondiale Turismo). Circa cinque anni fa per una serie di manovre al vertice organizzativo della Categoria del Turismo lui esce di scena e si mette subito al lavoro su una idea di vettura nuova, su un nuovo regolamento. Obiettivo: rilanciare una specialità in crisi per costi e, quindi, partecipazioni. Tre anni fa lanciò il TCR e oggi, alla vigilia della quarta stagione, il TCR diventa lo standard mondiale della Categoria Turismo. Un successo inarrestabile che conta oltre 50 Paesi dove si corrono i Campionati Nazionali secondo la regola TCR e un Ca...
2018-03-3035 min
Il podcast di Motorsport Republic+Intervista Marcello Lotti: WTCR, E-TCR. La crescita inarrestabile del Turismo da corsaMarcello Lotti era il manager esecutivo del WTCC (il Campionato Mondiale Turismo). Circa cinque anni fa per una serie di manovre al vertice organizzativo della Categoria del Turismo lui esce di scena e si mette subito al lavoro su una idea di vettura nuova, su un nuovo regolamento. Obiettivo: rilanciare una specialità in crisi per costi e, quindi, partecipazioni. Tre anni fa lanciò il TCR e oggi, alla vigilia della quarta stagione, il TCR diventa lo standard mondiale della Categoria Turismo. Un successo inarrestabile che conta oltre 50 Paesi dove si corrono i Campionati Nazionali secondo la regola TCR e un Ca...
2018-03-3034 mintcr! diaries - podcastA get-together this coming Saturday
content: Feb 17, 2018 · podcast: Mar 27, 2018
Audio (MP3): 20180217 - A get-together this coming Saturday
I’m *thinking* about having a get-together this coming Saturday, February 24th. If you’re reading this you’re invited. It would be a social mixer of sorts with snacks and drinks. No, I’m not making you all dinner. Tater-tots could possibly be available.
It would be kid friendly, too, since Maggie would also be hosting. Also, since you all know me you know that I don’t drink anymore. It’s not that I didn’t like drinking, it was more tha...
2018-03-2700 mintcr! diaries - podcastThrowing it on the floor
content: Feb 11, 2018 · podcast: Mar 16, 2018
Audio (MP3): 20180211 - Throwing it on the floor
I hate when I go to throw something away and then just end up throwing it on the floor. I mean, what the hell is this? It’s not like I’m threading the space shuttle needle in the vacuum of outer space.
And then I forgot to put a dryer sheet in with my clothes so when I pulled them from the dryer, they all looked as if they were made from the hide of the great northern yeti.
2018-03-1600 mintcr! diaries - podcastA cranberry stuck
content: Feb 9, 2018 · podcast: Mar 9, 2018
Audio (MP3): 20180209 - A cranberry stuck
The scene is my work desk. I'm eating cashew, almond, and cranberry trail mix. One of the cranberries jumped from the cup. I saw it happen but didn't hear the landing. After a mildly-extensive berry-hunt the fruit-trail gone-went cold. I cannot find the little asshole. I fear I may be walking around with a cranberry stuck on my ass for the rest of the day.
I'm gonna power down my computer. Pack up my snacks, shave my head, braid my beard. Leave t...
2018-03-0900 min
tcr! diaries - podcastHere's what happens when you unfriend someone
content: Feb 2, 2018 · podcast: Mar 7, 2018
Audio (MP3): 20180202 - Here's what happens when you unfriend someone
This showed up on my timeline just a little bit ago.
So Facebook “noticed” I unfriended somebody. I highly doubt if they just “noticed” anything. They KNOW our every move people. They track and follow said movements even when we’re not on their website or using their apps.
These social media overlords go so far as having shadow accounts of people that don’t have real, actual Facebook accounts. Oh yeah, it’s true. Your dead...
2018-03-0700 mintcr! diaries - podcastUnder Maggie's pillow
content: Jan 9, 2018 · podcast: Feb 16, 2018
Audio (MP3): 20180109 - Under Maggie's pillow
And then there was that one time maybe six or seven years ago when I ate a Snickers fun-size and hid the wrapper under Maggie’s pillow.
And then at bedtime when we found it and she was horrified of being convicted of a crime she didn’t commit, after she had time to process and I confessed, she thought it was funny.
And she still does. Because I asked her about it earlier tonight before dinner.
“And you tri...
2018-02-1600 mintcr! diaries - podcastMaggie and I talk bacon
content: Feb 2, 2018
Audio (MP3): 20180202 - Maggie and I talk bacon
I picked Maggie up from her mom's and on a whim we did a quick, off the cuff podcast in my truck on the way back home.
There's some background noise but that's what happens when you're recording while driving 45 mph. And yes, she was holding the phone and not me. Safety first kids.
Also, neither of us had prepared for this. Spontaneity in all its glory.
#maggie #diariespodcast
prokop
· Feb 2, 2018 at 5:49 pm
2018-02-0200 min
tcr! diaries - podcastWe don't want to spoil his suprise
content: Sep 21, 2017 · podcast: Nov 22, 2017
Audio (MP3): 20170921 - We don't want to spoil his suprise
In follow up to August 16th's Provocative yet professional
#email #hirasfashion #diariespodcast
keamoose
· Sep 21, 2017 at 7:31 pm
They did leave the door open for that with “and more”.
Have you seen this? http://thebloggess.com/2017/01/04/im-gonna-be-a-vampire-maybe/
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tcr!
· Sep 22, 2017 at 6:58 am
I hadn’t seen that but late last night I was all over it like a one-tooth...
2017-11-2200 mintcr! diaries - podcastAmazing blueberry jelly
content: Oct 19, 2017 · podcast: Nov 1, 2017
Audio (MP3): 20171019 - Amazing blueberry jelly
I hate it when I'm walking down the work hallway and I hear another office door open. Can't I just walk down the hall alone, with peace and quiet?
Now matter how much I try to avoid people, some random body shows up and says, "hello." And then I have to quickly scan the mental rolodex for non-offensive chit-chat. Engage in dialogue that obviously won't last more than 15 seconds.
It's not that I don't like the other office building inhabitants b...
2017-11-0100 mintcr! diaries - podcastMore knob twists
content: Oct 27, 2017 · podcast: Nov 1, 2017
Audio (MP3): 20171027 - More knob twists
I’m in the private, single person work restroom. Somebody tries the door knob. It refuses because I’m not an animal and therefore lock the door.
Again, with the twisting. I scowl at the door. More knob twists. This time as if brute force will unlock the door. I’m annoyed now.
Three seconds pass. The knob twists yet again. I call out forcefully, angrily... “dude, I’m taking a shit.”
I don’t like talking to people in publi...
2017-11-0100 min
tcr! diaries - podcastWhy are there so many pubes
content: Sep 18, 2017 · podcast: Oct 17, 2017
Audio (MP3): 20170918 - Why are there so many pubes
Why are there so many pubes in the damn urinals? What the hell are people doing in there? 🙄
#socialproblems #diariespodcast #publicrestroom
tcr!
· Sep 18, 2017 at 4:04 pm
Mona mentioned on FB, “folks not getting enough vitamins.”
So I made a sign…
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Love the show? Make a donatio...
2017-10-1700 min
tcr! diaries - podcastSunrise for Sep 27, 2017
content: Sep 27, 2017 · podcast: Sep 30, 2017
Audio (MP3): 20170927 - Sunrise for Sep 27 2017
Peeps, what was happening for me a few moments ago was a wonderful pinky orange sunrise. It’s Wednesday so we’re half-way through the week. Who can argue with hump day? NOBODY. That’s who.
Also, I could really use Desperately Seeking Susan on DVD. Ya, it’s from the 80s but still holding 88% on the Tomatoes. Bonus: if you have the soundtrack on vinyl you’ll be invited to the masquerade ball next month. Don’t just say you got it, y...
2017-09-3000 mintcr! diaries - podcastWhat's Happening in Geneva, Facebook group
content: Sep 24, 2017 · podcast: Sep 27, 2017
Audio (MP3): 20170924 - By the name a Thelma Louise
I may need to leave the What's Happening in Geneva Facebook group. I keep wanting to help with my web expert advice, wit, and charm. Below are two examples that I could barely resist (but did).
Hi there, I Need recommendation for washing machine fix.... thank
You're gonna go all the way down about half a block and you'll see a Torino with no wheels on it. Now, inside that Torino is my cousin, Jackie. N...
2017-09-2800 mintcr! diaries - podcastJul 2nd, 2017 at 2:42:05 am
content: Jul 2, 2017 · podcast: Sep 17, 2017
Audio (MP3): 20170702 - Starting tomorrow
Starting tomorrow I will randomly and routinely wake the cats up during the day because, no matter how many times we talk about this, they continually wake me up in the middle of the night with their bullshit. And yes, when I do it will be in such a way as to scare them shitless.
#cats #napsarespiritual #diariespodcast
tcr!
· Jul 2, 2017 at 4:38 pm
I really want to scare her shitless but she’s on my leg and I worry ther...
2017-09-1700 mintcr! diaries - podcasttcr! diaries podcast now available
content: Aug 21, 2017 · podcast: Sep 17, 2017
Audio (MP3): 20170821 - tcr diaries podcast now available
So this is a thing now. Keep your expectations low. I mean like really low. I don't know if it'll be anything more than just an audio version of a written piece. We'll see how it goes. Maybe I'll ad-lib now and then. Maybe I'll play the piano. At this point I'm just trying to get used to the sound of my own damn voice. 😘
You can listen on iTunes
And you can listen on SoundCloud
And you can list...
2017-09-1700 min
tcr!20170816 - Morning drinks mute the fires of hell.mp320170816 - Morning drinks mute the fires of hell.mp3 by tcr!
2017-08-1602 min
2017-08-1301 min
tcr!20170810 - Seeking colorful Christian martyr to repel repeated Jehovah's Witness20170810 - Seeking colorful Christian martyr to repel repeated Jehovah's Witness by tcr!
2017-08-1003 min
tcr!20170804 - Slip Slide Melting by For Love Not Lisa20170804 - Slip Slide Melting by For Love Not Lisa by tcr!
2017-08-0402 min
2013-09-1005 min
Fakultät für Biologie - Digitale Hochschulschriften der LMU - Teil 04/06Recognition of renal cell carcinoma by CD8+ and CD4+ TCR-engineered T lymphocytesImmunotherapy using T cells is a new approach that is being explored for the treatment of metastatic melanoma. For renal cell carcinoma (RCC), adoptive T cell therapy (ATT) is currently hampered by the lack of T cells expressing suitable T cell receptors (TCR). A tumor-infiltrating T cell population (TIL) was identified in our group (TIL-53) that showed a pattern of tumor recognition consistent with the requirements of a TCR applicable for immunotherapy. With the advent of genetic TCR engineering it was possible to further define the TIL specificity which was previously precluded by the failure to cultivate TIL-53. To achieve...
2011-02-2100 min
Journal Club Imunoterapia TumoralEdição#8: Flexibilidade do CDR3 do TCR comprovada por cristalografia. Implicações no reconhecimento antigénico pelos linfócitos T.Olá malta!
Neste oitava edição do Podcast Imunoterapia
Tumoral apresento-vos o artigo de Gakamsky
et al, publicado recentemente no jornal PNAS vol 104: 16639
de 2007.
Este artigo vem pela primeira vez corroborar com dados de
biofísica os dados apresentadas por vários
trabalhos baseados em cristalografia do complexo TCR/peptideo-MHC, e
onde é sugerida
de o domínio do CDR3 é capaz de uma certa
mobilidade e capacidade de adaptar-se ("fiting") à
superfície tri-dimensional do complexo
peptídeo-MHC.
Para relembrar: o TCR é o receptor da célula T,
que reconhece peptídeos (oligopeptideos) apresentados pela
molecula Major de Histocompatibilidade (MHC). As células T
são de...
2007-12-0818 min