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ASTCT
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ASTCT Talks
Delayed Neurotoxicity With Car-T Therapy in Myeloma: What Clinicians Need To Know
In this episode of ASTCT Talks, Dr. Rahul Banerjee sits down with Dr. Kenneth Lim and Dr. Yi Lin of Mayo Clinic to discuss a critical and emerging topic in CAR T-cell therapy: delayed neurotoxicities following cilta-cel treatment in multiple myeloma. They break down the clinical features of nerve palsies and Parkinsonism-like symptoms, share diagnostic and treatment strategies and explore emerging predictive markers like absolute lymphocyte count. Given that cilta-cel is increasingly being used in second-line myeloma treatment and is even being studied in first-line treatment to replace stem cell transplantation, this conversation is a timely and insightful look at imp...
2025-07-17
21 min
ASTCT Talks
Titans of Transplant: Dr. Daniel Weisdorf
In the next installment of ASTCT's Titans of Transplant series, Dr. Shernan Holtan sits down with Dr. Daniel Weisdorf—renowned leader, mentor and pioneer in cellular therapy and transplantation—for a reflective and engaging conversation on the evolution of the field. From the early days of sibling-only donors and bone marrow harvests to today’s innovations in GVHD prophylaxis and cord blood transplantation, Dr. Weisdorf shares personal anecdotes, pivotal clinical insights and lessons in mentorship, writing and research. Together, they explore the milestones, challenges and future directions in transplant and cellular therapy—offering a powerful...
2025-06-25
1h 06
ASTCT Talks
CAR T and Transplantation Advances Across Hematologic Cancers at ASCO 2025
An expert panel highlights key presentations in multiplemyeloma, lymphoma, and other hematologic malignancies at the 2025 ASCO Annual Meeting.CancerNetwork®, in collaboration with The American Society for Transplantation and Cellular Therapy (ASTCT), organized an X Space hosted by Rahul Banerjee, MD, FACP; Taha Al-Juhaishi, MD; and Muhammad Salman Faisal, MD. This expert panel convened to discuss key presentations and abstracts of interest at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting featuring noteworthy developments in modalities like CAR T-cell therapy and transplantation across multiple myeloma, lymphoma, and other disease types.Banerjee is an assistant professor i...
2025-06-17
35 min
Oncology On The Go
CAR T and Transplantation Advances Across Hematologic Cancers at ASCO 2025
CancerNetwork®, in collaboration with The American Society for Transplantation and Cellular Therapy (ASTCT), organized an X Space hosted by Rahul Banerjee, MD, FACP; Taha Al-Juhaishi, MD; and Muhammad Salman Faisal, MD. This expert panel convened to discuss key presentations and abstracts of interest at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting featuring noteworthy developments in modalities like CAR T-cell therapy and transplantation across multiple myeloma, lymphoma, and other disease types. Banerjee is an assistant professor in the Clinical Research Division at the Fred Hutchinson Cancer Center in Seattle, Washington. Al-Juhaishi is the associate director of the H...
2025-06-09
35 min
ASTCT Talks
Homegrown CAR-T: Expanding Access Through Academic Innovation
In this episode of ASTCT Talks, Dr. Taha Al-Juhaishi welcomes Dr. Marcos de Lima, hematologist-oncologist at The Ohio State University Comprehensive Cancer Center, to explore the rapidly evolving field of homegrown CAR-T therapies. Together, they dive into the definitions, motivations and barriers of decentralized CAR-T manufacturing, the global innovation landscape and what it takes to build sustainable academic cell therapy programs. Dr. de Lima shares his firsthand experience launching point-of-care CAR-T programs, the regulatory and payer landscape and the future of academic-industry collaboration in expanding access. It’s a must-listen for anyone interested in the future of decentralized cell th...
2025-06-04
43 min
ASTCT Talks
Homegrown CAR-T: Expanding Access Through Academic Innovation
In this episode of ASTCT Talks, Dr. Taha Al-Juhaishi welcomes Dr. Marcos de Lima, hematologist-oncologist at The OhioState University Comprehensive Cancer Center, to explore the rapidly evolving field of homegrown CAR-T therapies. Together, they dive into the definitions, motivations and barriers of decentralized CAR-T manufacturing, the globalinnovation landscape and what it takes to build sustainable academic cell therapy programs. Dr. de Lima shares his firsthand experience launching point-of-care CAR-T programs, the regulatory and payer landscape and the future of academic-industry collaboration in expanding access. It’s a must-listen for anyone interested in the future of decentralized cell therapy and in...
2025-06-04
43 min
ASTCT Talks
Rethinking Tacrolimus Targets in the PTCy Era
In this episode of ASTCT Talks, Dr. Shernan Holtan welcomes Andrew Lin, Manager of Clinical Pharmacy Services of Adult BMT and CTS at Memorial Sloan Kettering Cancer Center, to discuss the evolving role of tacrolimus levels in GVHD prophylaxis within the post-transplant cyclophosphamide (PTCy) era. They explore findings from a recent retrospective study examining whether higher tacrolimus levels offer added protection against GVHD, what this means for toxicity and patient outcomes and how these insights are shaping dosing strategies. The conversation also looks ahead to future research areas, including MMF optimization and the potential for simplified, patient-centered prophylaxis regimens.
2025-05-19
13 min
ASTCT Talks
Reviewing Real-World Use of Beti-Cel in Transfusion-Dependent β-Thalassemia
In a special co-branded episode between Oncology On theGo hosted by CancerNetwork® and the American Society for Transplantation and Cellular Therapy (ASTCT)’s program ASTCT Talks, Nora M. Gibson, MD, MSCE, and Taha Al-Juhaishi, MD, spoke about real-world applications of betibeglogene autotemcel (beti-cel; Zynteglo) as a treatment for patients with beta (β)-thalassemia.They spoke in the context of a study that Gibson presented at the 2025 Tandem Meetings, which evaluated patients who received commercial beti-cel in a single-center cohort following the agent’s FDA approval in August 2022. ¹ ²Nora is a fourth-year fellow in bone marrow transplant andcellular therapy at the C...
2025-05-05
24 min
Oncology On The Go
Reviewing Real-World Use of Beti-Cel in Transfusion-Dependent β-Thalassemia
In a special co-branded episode between Oncology On the Go hosted by CancerNetwork® and the American Society for Transplantation and Cellular Therapy (ASTCT)’s program ASTCT Talks, Nora M. Gibson, MD, MSCE, and Taha Al-Juhaishi, MD, spoke about real-world applications of betibeglogene autotemcel (beti-cel; Zynteglo) as a treatment for patients with beta (β)-thalassemia. They spoke in the context of a study that Gibson presented at the 2025 Tandem Meetings, which evaluated patients who received commercial beti-cel in a single-center cohort following the agent’s FDA approval in August 2022. Nora is a fourth-year fellow in bone marrow transplant and cellular therap...
2025-05-05
24 min
ASTCT Talks
Key CAR T and Transplantation Presentations From The 2025 Tandem Meeting
CancerNetwork®, in collaboration with the American Society for Transplantation and Cellular Therapy (ASTCT)®, hosted a Twitter/X Space during the 2025 Tandem Meetings. The live conversation featured Rahul Banerjee, MD, FACP, of Fred Hutchinson Cancer Center, and Shernan Holtan, MD, of Roswell Park Comprehensive Cancer Center. Together, they shared expert commentary on new data in CAR T-cell therapy and hematopoietic cell transplantation.With insights drawn from posters, oral abstracts, and late-breaking presentations, the session unpacked both clinical takeaways and implications for patient care.Highlights included:LBA1 – Ide-cel + lenalidomide maintenance post-transplant in MM patients“This m...
2025-04-24
56 min
ASTCT Talks
Understanding Cutaneous GVHD: Clinical Insights and Care Strategies
Welcome to the fourth episode of ASTCT Talks’ exclusive 8-part series, supported by an educational grant from Sanofi US. In this episode, former ASTCT President Dr. Corey Cutler sits down with Dr. Connie R. Shi from the Cutaneous Oncology Program at Dana-Farber Cancer Institute. They discuss Dr. Shi's recent article, Cutaneous Chronic Graft-Versus-Host Disease: Clinical Manifestations, Diagnosis, Management, and Supportive Care.Tune in as they explore the complexities of cutaneous GVHD, including acute and chronic presentations, diagnostic challenges and skin-directed treatment strategies such as topical steroids and phototherapy. They also cover key considerations for recognizing and diagnosing cu...
2025-04-18
26 min
Oncology On The Go
Key CAR T and Transplantation Presentations From The 2025 Tandem Meeting
CancerNetwork®, in collaboration with The American Society for Transplantation and Cellular Therapy (ASTCT), organized an X Space hosted by Rahul Banerjee, MD, FACP, an assistant Professor in the Clinical Research Division at the Fred Hutchinson Cancer Center in Seattle, Washington, and Shernan Holtan, MD, the chief of Blood and Marrow Transplantation and professor of Medicine at Roswell Park Comprehensive Cancer Center. The conversation took place during the 2025 Tandem Meeting and highlighted many significant presentations and posters on CAR T-cell therapies and transplantation, Banerjee’s and Holtan’s respective areas of expertise. The following trials were discussed: LBA1 - Phas...
2025-03-03
56 min
ASTCT Talks
The Role of Lifestyle Medicine in Chronic GVHD with Dr. Steven Pavletic
Welcome to the third episode of ASTCT Talks’ exclusive 8-part series, supported by an educational grant from Sanofi US. In this series, ASTCT President Dr. Corey Cutler sits down with authors from the latest Graft-versus-Host Disease and Late Effects Following Allogeneic Transplantation journal collection to discuss their research and its implications for patient care.In this episode, Dr. Cutler is joined by Dr. Steven Z. Pavletic, the GVHD and Late Effects Section and Myeloid Malignancies Program Director at the NIH in Bethesda, Maryland. Widely recognized as a titan in chronic GVHD research, Dr. Pavletic explores an emerging ye...
2025-02-13
25 min
ASTCT Talks
Optimizing Graft Selection: A New Era in Transplantation with Dr. Lori Muffly
In this episode of ASTCT Talks, Dr. Taha Al-Juhaishi welcomes Dr. Lori Muffly, Associate Professor in the Division of Blood and Marrow Transplantation-Cellular Therapies at Stanford University, to discuss groundbreaking advancements in graft selection and manipulation in hematopoietic cell transplantation. They explore the evolution of graft engineering strategies aimed at improving patient outcomes, with a focus on Orca-T, an innovative cell therapy designed to reduce graft-versus-host disease while maintaining graft-versus-leukemia effects. Dr. Muffly provides insights into the clinical development of this promising therapy, its impact on patient recovery, and the future of transplantation. Tune in to learn about the...
2025-01-23
39 min
ASTCT Talks
Oral Chronic Graft-Versus-Host Disease and Oral Health After Allogeneic Hematopoietic Cell Transplantation — What the Care Team Needs To Know
Welcome to the second installment of an exclusive 8-part ASTCT Talks series, supported by an educational grant from Sanofi US. In this series, ASTCT President Dr. Corey Cutler speaks with authors from each article in the latest Graft versus Host Disease and Late Effects Following Allogeneic Transplantation Journal collection. In this episode, Dr. Cutler is joined by Dr. Nathaniel S. Treister, a recognized expert in oral medicine, to discuss the intricacies of oral chronic GVHD and its impact on oral health following allogeneic hematopoietic cell transplantation. They explore the diagnostic criteria, effective management strategies, and long-term care...
2024-12-11
22 min
ASTCT Talks
Titans of Transplant: Dr. Renier Brentjens
In the next episode of ASTCT's "Titans of Transplant," Dr. Shernan Holtan hosts Dr. Renier Brentjens, a pioneer in CAR T-cell therapy and a transformative leader in transplantation and cellular therapy. Dr. Brentjens discusses the challenges and breakthroughs behind developing the first chimeric antigen receptors (CARs), the pivotal discovery of CD19-targeting hybridomas, and the determination needed to turn bold ideas into clinical reality. Tune in for an insightful look at how early experiments paved the way for today’s CAR T-cell advancements, capturing the passion, persistence, and pivotal moments that shaped a new era in cancer treatment.
2024-11-12
1h 07
ASTCT Talks
Understanding Ocular Graft-versus-Host Disease to Facilitate an Integrated Multidisciplinary Approach
Welcome to the first installment of an exclusive 8-part ASTCT Talks series, supported by an educational grant from Sanofi US. In this series, ASTCT President Dr. Corey Cutler speaks with authors from each article in the latest ASTCT Journal of Transplantation and Cellular Therapy GVHD supplement. In this opening episode, Dr. Cutler is joined by Dr. Katie Luo, a leading ophthalmologist, to discuss the complexities of ocular GVHD, why it goes beyond “just dry eye,” and how an integrated, multidisciplinary approach can offer better patient outcomes. For further insights, read Dr. Luo’s full article, “Understa...
2024-10-29
22 min
ASTCT Talks
Leveraging Ex Vivo Gene Therapy Advancements in Hemoglobinopathies and Metabolic Diseases
In a special co-branded episode between Oncology On the Go hosted by CancerNetwork® and the American Society for Transplantation and Cellular Therapy (ASTCT)’s program ASTCT Talks, Alexis K. Kuhn, PharmD, BCOP, spoke with Katie Bruce, PharmD, BCPPS, and Susie Long, PharmD, about the use of approved cell-based gene therapies for patients with sickle cell disease, beta thalassemia, adrenoleukodystrophy (ALD), and metachromatic leukodystrophy (MLD). These panelists shared the pharmacist’s perspective on ensuring quality care with these ex vivo gene therapies across all treatment phases, including mobilization, conditioning, and infection prophylaxis. Kuhn is an ambulatory Pedia...
2024-10-22
47 min
Oncology On The Go
Leveraging Ex Vivo Gene Therapy Advancements in Hemoglobinopathies and Metabolic Diseases
In a special co-branded episode between Oncology On the Go hosted by CancerNetwork® and the American Society for Transplantation and Cellular Therapy (ASTCT)’s program ASTCT Talks, Alexis K. Kuhn, PharmD, BCOP, spoke with Katie Bruce, PharmD, BCPPS, and Susie Long, PharmD, about the use of approved cell-based gene therapies for patients with sickle cell disease, beta thalassemia, adrenoleukodystrophy (ALD), and metachromatic leukodystrophy (MLD). These panelists shared the pharmacist’s perspective on ensuring quality care with these ex vivo gene therapies across all treatment phases, including mobilization, conditioning, and infection prophylaxis. Kuhn is an ambulatory Pediatric Hematology/Oncology/BMT P...
2024-10-21
47 min
ASTCT Talks
Outpatient CAR T: Navigating Logistics and Patient Care
This episode of ASTCT Talks dives into outpatient CAR T therapy, exploring logistics, challenges, and success strategies. Host Dr. Zahra Mahmoudjafari leads a panel of experts to share insights from their innovative programs. The panel features Robb Richards, Administrative Director of Cell Therapy and Transplant at Penn Medicine; Dr. Katie Gatwood, Clinical Pharmacy Specialist at Vanderbilt University Medical Center; and Dr. Taha Al-Juhaishi, Associate Director at the University of Oklahoma’s Transplant and Cell Therapy Program. Topics include outpatient program structures, toxicity management, and the evolving role of cell therapies beyond hematologic malignancies. ...
2024-10-14
37 min
ASTCT Talks
Bridging the Gap: Addressing Disparities in GVHD Care
In this episode of ASTCT Talks, host Dr. Andrés Gómez De León is joined by Dr. Nandita Khera and Dr. Alexandra Gomez Arteaga to explore the critical issue of disparities and barriers to care in graft-versus-host disease (GVHD). The discussion delves into the factors contributing to unequal access to hematopoietic cell transplantation, such as socioeconomic status, race, and ethnicity, both in the U.S. and globally. The guests highlight initiatives like the ACCESS Initiative by ASTCT and the National Marrow Donor Program, aimed at addressing these disparities through advocacy, awareness, and training for junior faculty. They als...
2024-09-25
42 min
ASTCT Talks
Managing Secondary Cancer Risks After CAR T-Cell Therapy in Multiple Myeloma Subgroups
In a special co-branded episode between Oncology On the Go and the American Society for Transplantation and Cellular Therapy (ASTCT)’s program ASTCT Talks, Rahul Banerjee, MD, FACP, and Noopur Raje, MD, discussed the risk of secondary malignancies in patients with multiple myeloma who receive CAR T-cell therapy. Banerjee is an assistant professor in the Clinical Research Division of Fred Hutchinson Cancer Center and an assistant professor in the Division of Hematology and Oncology at the University of Washington. Raje is the director of the Center for Multiple Myeloma at Massachusetts General Hospital Cancer Cente...
2024-09-03
18 min
Oncology On The Go
Managing Secondary Cancer Risks After CAR T-Cell Therapy in Multiple Myeloma Subgroups
In a special co-branded episode between Oncology On the Go and the American Society for Transplantation and Cellular Therapy (ASTCT)’s program ASTCT Talks, Rahul Banerjee, MD, FACP, and Noopur Raje, MD, discussed the risk of secondary malignancies in patients with multiple myeloma who receive CAR T-cell therapy. Banerjee is an assistant professor in the Clinical Research Division of Fred Hutchinson Cancer Center and an assistant professor in the Division of Hematology and Oncology at the University of Washington. Raje is the director of the Center for Multiple Myeloma at Massachusetts General Hospital Cancer Center and a professor of...
2024-09-02
18 min
ASTCT Talks
Exploring Insights From CAR-TITUDE 4 and KarMMa-3 Trials with Dr. Jens Hillengass
In this episode of ASTCT Talks, Dr. Muhammad Salman Faisal is joined by Dr. Jens Hillengass. Dr. Hillengass discusses the latest advancements in CAR T cell therapy, focusing on its application in early-line settings following the results of the CAR-TITUDE 4 and KarMMa-3 trials. Tune in as he shares insights on the efficacy, patient selection and future directions of CAR-T cell therapy in multiple myeloma. This episode is supported by Johnson & Johnson and Legend Biotech. Don’t miss out on this informative discussion with one of the leading experts in the field. About Dr. Jens Hillengass Je...
2024-07-20
24 min
ASTCT Talks
A New Era in GVHD Prophylaxis: A Conversation With Dr. Samer Al-Homsi
In this episode of "ASTCT Talks," Dr. Shernan Holtan sits down with Dr. Samer Al-Homsi, as he shares his insights on the future of graft versus host disease (GVHD) prophylaxis, particularly in haploidentical transplantation. Dr. Al-Homsi delves into the innovative CAST regimen, which combines post-transplant cyclophosphamide, abatacept and short-duration tacrolimus. Learn about the challenges, breakthroughs and promising results that could revolutionize how we approach GVHD prevention and treatment, making a future without GVHD a reality. Listen in as we explore the potential for reducing transplant toxicities and the impact on patient care. About...
2024-06-25
29 min
ASTCT Talks
Beyond Remission: Navigating the Late Effects of Pediatric CAR T-Cell Therapy
In this episode "ASTCT Talks,” hosts Rebecca Epperly, MD, and Aimee Talleur, MD, from St. Jude Children's Research Hospital, dive into the pioneering realm of CAR T-cell therapy and its late effects on pediatric patients. The discussion unfolds at the intersection of innovation and caution, highlighting the recent sessions from the 2024 Tandem meetings. They explore the emerging challenges and lack of data concerning long-term impacts of this revolutionary treatment, particularly in pediatric, adolescent, and young adult populations. This episode sheds light on both the immense potential and the imperative need for comprehensive studies to better understand and mitigate the lo...
2024-04-29
24 min
ASTCT Talks
A Conversation with Mike Niles: Author of ‘Hard Graft: Our Fight Against Killer Blood’
In this latest episode of ASTCT Talks, Rachel Schollmeier and NMDP’s Samantha Watters host author Mike Niles, delving into the captivating history of the Anthony Nolan bone marrow transplant register. Explore the evolution of transplantation, from no donor registries to international initiatives, and gain a deeper understanding of the challenges faced by bone marrow registries today. Discover the inspiring narratives behind bone marrow donation and the transformative advancements that continue to shape the future of transplantation. Plus, don't miss the chance to connect with Samantha's podcast, NMDP ‘Explore Cell Therapy,' for even more insights into the world of c...
2024-02-12
41 min
ASTCT Talks
Titans of Transplant: Dr. Stephanie Lee
In the next installment of ASTCT’s Titans of Transplant series, Dr. Stephanie Lee is interviewed by Dr. Jennifer Saultz. Dr. Lee shares her journey from Seattle to becoming a professor at Fred Hutch Cancer Center. The conversation highlights early motivations, challenges faced during fellowship, and the influence of her father's advice to always strive for the best. They also discuss Dr. Lee's groundbreaking work in chronic graft-versus-host-disease research, collaborative efforts, FDA-approved treatments, and the evolving landscape in the field. The Titans of Transplant series seeks to recognize, celebrate and chronicle the physicians, researchers, pharmacists, nu...
2024-01-16
18 min
ASTCT Talks
Exploring the BMT CTN 1703 Study
In this latest episode of ASTCT Talks, Dr. Andrés Gómez De León sits down with Dr. Javier Bolaños-Meade. They delve into the groundbreaking BMT CTN 1703 study. Together, they explore the historical context of GVHD prophylaxis, the evolution of post-transplant cyclophosphamide (PTCy), and the essential contributions of the BMT CTN in transplantation research. Dr. Bolaños-Meade provides key insights into the study's design, conditioning regimens, and cell doses. The episode unravels the intricacies of PTCy, addressing both its merits and potential drawbacks, including Grade 2 infections, CMV reactivation, and cardiotoxicity, offering an exploration of the trans...
2023-12-04
54 min
ASTCT Talks
Navigating CAR-T Survivorship
In this latest episode of ASTCT Talks, Cory M. Edgar, DMSc, PA-C, sits down with Sarah Fitzmaurice, APRN, where they delve into the evolving landscape of survivorship care, particularly in the realm of CAR T-cell therapy. They discuss the development of CAR T-specific protocols, emphasizing the importance of post-treatment monitoring and patient education. They also explore the challenges of defining survivorship, the multidisciplinary nature of care, and insights into late effects, deconditioning, cognitive changes, and psychological concerns beyond the first year. Tune into this episode of ASTCT Talks for a deep dive into the...
2023-11-28
40 min
ASTCT Talks
Beyond BCMA: Exploring Talquetamab in Myeloma Therapy
In this latest episode of ASTCT Talks, Dr. Rahul Banerjee, MD, FACP, sits down with Dr. Amrita Krishnan, MD. They delve into the use of GPRC5D as a target in myeloma therapy, specifically focusing on Talquetamab. Dr. Krishnan shares insights from the MonumenTAL-1 trial, discussing the dosing schedules and response rates with GPRC5D-targeted therapy. They explore the unique toxicities associated with this treatment, such as cytokine release syndrome and skin and nail toxicities. The conversation also touches on the considerations for patients who have previously received BCMA-targeted therapies and the potential of...
2023-11-15
17 min
ASTCT Talks
Behind the Scenes of CAR-T Therapy at University of California, Davis
In this latest episode of ASTCT Talks, Misty Evans, DNP, APRN, CPNP-AC, sits down with Flora Stondell, FNP, to delve into the intricacies of University of California, Davis’ (UC Davis’) transplant and cellular therapy program, with a specific focus on CAR T cell therapy. In this insightful conversation, they discuss topics such as patient access, the timeline from referral to CAR-T therapy initiation, overcoming insurance barriers, and the patient education process. Stondell shares valuable insights gained from her experience in the field, highlighting the crucial role of advanced practice providers (APPs) in delivering high-quality care...
2023-11-01
29 min
ASTCT Talks
Revitalizar, Prosperar y Sobrevivir: El Poder del Movimiento en la Recuperación de los Trasplantes
En este último episodio de ASTCT Talks, el Mensaje del Presidente de octubre, el Dr. Andrés Gómez De León está acompañado por el Dr. Miguel Perales, Presidente de ASTCT y Jefe del Servicio de Trasplante de Médula Ósea en Adultos del Memorial Sloan Kettering Cancer Center y Profesor de Medicina en Facultad de Medicina Weill Cornell. Profundizan en el papel vital, pero a menudo pasado por alto, de la actividad física en los trasplantes de terapia celular y hematopoyética, discutiendo desafíos, enfoques proactivos como la "prehabitación", la brecha en la investigació...
2023-10-16
23 min
ASTCT Talks
Revitalize, Thrive, and Survive: The Power of Movement in Transplant Recovery
In this latest episode of ASTCT Talks, the October President's Message, Dr. Andrés Gómez De León is joined by Dr. Miguel Perales, President of ASTCT and Chief of the Adult Bone Marrow Transplantation Service at Memorial Sloan Kettering Cancer Center and Professor of Medicine at Weill Cornell Medical College. They delve into the vital but often overlooked role of physical activity in hematopoietic and cell therapy transplants, discussing challenges, proactive approaches like "pre-hab," the research gap, and the transformative effects of movement on recovery. Click here to listen to this episode in...
2023-10-16
18 min
ASTCT Talks
A PTCy of Relief: GVHD Prophylaxis in Matched Unrelated Donors
In this latest episode of ASTCT Talks, Dr. Rebecca Gonzalez sits down with Dr. Katie Gatwood and Dr. Timothy Porter to kick off National Pharmacy Month by discussing the clinical implications of post-transplant cyclophosphamide (PTCy) use outside of the haploidentical setting. They delve into their respective cancer centers' primary donor sources for match unrelated donors and the breakdown of conditioning intensity within their hematologic patients. They delve into the future of PTCy discussing the potential for earlier de-escalation of immunosuppressants to limit drug-related toxicities and optimize patient outcomes as well as important supportive care considerations. Despite the exciting prospects...
2023-10-12
45 min
ASTCT Talks
Navigating Intersectionality in GVHD and Transplant Medicine
In this latest episode of ASTCT Talks, we sit down with Associate Professor Nada Hamad, senior staff specialist in bone marrow transplant, and a clinical and laboratory hematologist at St. Vincent’s hospital in Sydney, to explore the impact of intersectionality on graft-versus-host disease (GVHD) in transplant recipients. She dives into how gender and race can compound biases in research, education, and clinical practice, affecting GVHD severity and outcomes. Further discussions center on the need for research into how age, socioeconomic status, and geographic region intersect with GVHD incidence and treatment strategies. In addition, Nada stresses the need to in...
2023-09-28
39 min
ASTCT Talks
Advancing ALL Treatment and Insights on MRD Monitoring
In this latest episode of ASTCT Talks, Christina Cho, MD, interviews Lori Muffly, MD, MS. During the conversation, Dr. Muffly emphasizes the need for more randomized data in ALL treatment and addresses the unique challenges of treating young adults, including fertility preservation. Dr. Muffly also emphasizes the significance of measurable residual disease (MRD) monitoring using the clonoSEQ® Assay, offering valuable insights into leukemia care. About Lori Muffly, MD, MS Lori Muffly, MD, MS, an Associate Professor of Medicine at Stanford University, specializes in adult acute leukemia research, clinical trials, and hematopoietic cell transplantation. Her work f...
2023-09-18
39 min
ASTCT Talks
Monitoring After CAR-T Therapy for Multiple Myeloma: The APP Perspective
In this latest episode of ASTCT Talks, Rahul Banerjee interviews Josh Epworth, a lead nurse practitioner in the plasma cell disorders clinic at the Fred Hutchinson Cancer Center. They delve into the topic of monitoring after CAR-T therapy for multiple myeloma. Mr. Epworth shares insights from his experience in the outpatient setting, discussing issues like hypogammaglobulinemia, immune cell functionality, and infections that may arise after CAR-T treatment. They also touch on monitoring for cytomegalovirus (CMV) and other respiratory viruses, as well as the importance of developing close relationships with local healthcare providers to ensure patients receive timely care.
2023-08-18
25 min
Cancer Care Connections
CAR T-Cell Therapy: Engineering the Immune System to Fight Cancer
On this week’s episode of Cancer Care Connections, Cheryl Tan spoke with Dr. Gary Simmons. Dr. Simmons is a hematologist oncologist and part of the transplant and cellular therapy team for Virginia Oncology Associates. Cheryl and Dr. Simmons dove into CAR T-cell therapy, how it is a revolutionary treatment for fighting blood cancer, and how continued research of CAR T could change the landscape of cancer treatment.If you haven't already, consider listening to episode 2, Introduction to Blood Cancer with Dr. Jared Kobulnicky. He presented a high-level overview of what blood cancer is and the latest dev...
2023-08-09
25 min
ASTCT Talks
Titans of Transplant: Dr. Rick Jones
In this latest episode of ASTCT Talks, Dr. Tania Jain engages in a conversation with Dr. Richard Jones, the BMT director and co-director of the Hematologic Malignancies Programs at Johns Hopkins University. He shares his journey in the field of oncology and transplantation, reflecting on the life events and experiences that led him to this path. He delves into the groundbreaking development of post-transplant cyclophosphamide (PTCy) and its significant impact on transplant procedures. Gain insights into the behind-the-scenes efforts and the role PTCy has played in expanding donor options and improving graft-versus-host disease prophylaxis. The episode also highlights Dr...
2023-07-17
27 min
Blood Cancer Talks
Episode 25. Managing Acute Toxicities of CAR T-cell Therapy
In this episode, we discuss the management of acute toxicities of CAR T-cell therapy, including CRS, ICANS, and HLH with Dr. Michael Jain from Moffitt Cancer Center.Here are some of the key articles we discussed:1. “How I treat refractory CRS and ICANS after CAR T-cell therapy”. https://pubmed.ncbi.nlm.nih.gov/36989488/ 2. CAR-HEMATOTOX score: https://pubmed.ncbi.nlm.nih.gov/34166502/ 3. “How I treat cytopenias after CAR T-cell therapy”. https://pubmed.ncbi.nlm.nih.gov/36800563/ 4. Immune Effector Cell-Associated HLH-L...
2023-06-28
49 min
ASTCT Talks
Breaking Barriers and Dispelling Misconceptions in Transplantation
In this latest episode of ASTCT Talks, the June President's Message, we are joined by Dr. Miguel Perales, President of ASTCT and Chief of the Adult Bone Marrow Transplantation Service at Memorial Sloan Kettering Cancer Center and Professor of Medicine at Weill Cornell Medical College. This episode features a personal story of a patient with aggressive lymphoma who initially had doubts about the effectiveness of transplantation but ultimately experienced a fulfilling life post-transplant. Dr. Perales' story underscores the significance of educating colleagues about improved outcomes and advancements in cell therapies. He also delves into the primary barriers to access...
2023-06-20
13 min
ASTCT Talks
How to Handle CAR-T Waitlists in Multiple Myeloma
In this latest episode of ASTCT Talks, Christina Ferraro, MSN, APRN-CNP, BMTCN, is joined by Beth Faiman, PhD, MSN, APN-BC, AOCN, BMTCN, FAAN, FAPO, to discuss criteria used to determine who is eligible for CAR-T cells, efforts between multi-disciplinary teams to select patients, ethical implications in patient selection and more. About Christina Ferraro Christina Ferraro completed her bachelor of science in nursing at The Ohio State University in 2001 and received a master of science in nursing and certification as a family nurse practitioner from Kent State University in 2016. She joined the Cleveland Clinic in 2003 as...
2023-05-18
18 min
ASTCT Talks
Treating Cytopenias After CAR T-cell Therapy
In this latest episode of ASTCT Talks, Dr. Rahul Banerjee, MD, FACP, sits down with Dr. Tania Jain, MBBS. They dive into "How I Treat Cytopenias after CAR T-cell Therapy,” a paper published by Dr. Jain and co-authors (Timothy S. Olson, MD, PhD and Frederick Locke, MD) in Blood in February 2023. They discuss why cytopenias occur after CAR-T therapy, how to evaluate cytopenias after CAR-T therapy, who best to manage cytopenias after CAR-T and more. About Dr. Rahul Banerjee, MD, FACP Dr. Banerjee, MD, FACP, (@RahulBanerjeeMD) is an Assistant Professor in the Division of Medical On...
2023-05-05
22 min
The PQI Podcast
Season 4 Ep. 15 : Oncology Workforce Collaborative
This week we sit down with Alison Gulbis, PharmD, BCOP, Kamakshi Rao, PharmD, BCOP, FASHP, and Zahra Mahmoudjafari, PharmD, MBA, BCOP, FHOPA to discuss their work on the Oncology Workforce Collaborative. Alison is a Clinical Pharmacy Manager at the University of Texas MD Anderson Cancer Center in Houston, TX. She obtained her PharmD at the University of Florida and completed her PGY1 and PGY2 residencies at the Medical University of South Carolina. She has been in clinical practice for 19 years at MD Anderson and manages a team of clinical pharmacy specialists in pediatric hematology/oncology and adult s...
2023-04-27
25 min
ASTCT Talks
Bispecific Antibodies in Myeloma: The Who, What, When, and Where
In this latest episode of ASTCT Talks, Dr. Rahul Banerjee, MD, FACP, sits down with Dr. Urvi A. Shah, MD, to discuss CAR-T vs bsAbs among academic audiences, bispecific antibodies (in particular commercially available teclistamab), future cycles of teclistamab, infections in published trials of bsAbs in myeloma and more. About Dr. Rahul Banerjee, MD, FACP Dr. Banerjee, MD, FACP, (@RahulBanerjeeMD) is an Assistant Professor in the Division of Medical Oncology at the University of Washington and at the Fred Hutchinson Cancer Center. Prior to moving to Seattle, he completed his hematology/oncology fellowship and advanced...
2023-04-18
18 min
ASTCT Talks
Virus-Specific T-Cells (VST): Where We Are and How We Got Here
In this latest episode of ASTCT Talks, Dr. Genovefa Papanicolaou, MD sits down with Dr. Richard J. O'Reilly, MD and Professor Karl S. Peggs, MB, BCh, MA, MRCP, FRCPath to discuss Virus-Specific T-Cells (VST). They dive into what VSTs are, safety of VSTs, challenges and opportunities of adoptive cell therapy for viruses and more. Disclaimer: Dr. Richard O’Reilly received royalties following licensure of the EBV-specific T-cell bank by Atara Biotherapeutics and has subsequently received research support and consultant fees from Atara Biotherapeutics. About Genovefa Papanicolaou, MD Genovefa Papanicolaou (@GenPapaMD) is an infectious di...
2023-04-06
55 min
Healio Minute
Leukemia Edition: Top Headlines for Week of March 27, 2023
In this edition, optimal antibiotics timing among inpatients with cancer; inflammation levels linked to survival in acute myeloid leukemia; dexrazoxane confers long-term cardioprotection for pediatric cancer and more. Read the full coverage here: Optimal antibiotics timing ‘likely differs’ among inpatients with cancer, neutropenic fever Inflammation levels linked to survival in acute myeloid leukemia Dexrazoxane confers long-term cardioprotection after anthracyclines for pediatric cancer Menin inhibitor produces high response rates in certain acute leukemia subtypes Tisa-cel CAR-T reinfusion lacks durability for younger patients with B-cell ALL References:
2023-03-30
14 min
Healio Minute
Leukemia Edition: Top Headlines for Week of March 13, 2023
In this edition, outpatient HSCT feasible for older adults; ponatinib for newly diagnosed Ph+ALL; iomab-B may increase transplant access in relapsed/refractory AML and more. Read the full coverage here: Outpatient HSCT feasible for older adults with AML, myelodysplastic syndrome Ponatinib ‘should be considered a standard of care’ for newly diagnosed Ph+ALL Iomab-B may increase transplant access, improve outcomes in relapsed/refractory AML Living along US-Mexico border linked to higher risk for death among children with leukemia Breyanzi study meets complete response endpoint for leukemia, lymp...
2023-03-16
14 min
ASTCT Talks
Titans of Transplant: Dr. Micah Skeens
In the next installment of ASTCT’s Titans of Transplant series, Dr. Micah Skeens, PhD, MS, CPNP-PC, is interviewed by Darren J. Johnson, PA. They dive into her story and background as a pediatric oncology nurse of over 20 years and current research interests and passions, including development of an app for medical adherence in transplant. They also discuss importance of mentorship in the field for APPs, the value in making a difference in patients’ lives, current inspirations and more. About Darren J. Johnson Darren J. Johnson, PA, is a physician assistant who has been working in t...
2023-03-15
33 min
Health Professional Radio - Podcast
How Some Bone Marrow/Stem Cell Transplants Can Lead to Complications
Dr. Corey Cutler, MD, MPH, FRCPC, Medical Director, Stem Cell Transplant Program, Dana-Farber Cancer Institute and Vice President, American Society for Transplantation and Cellular Therapy (ASTCT) and GVHD patient Meredith A. Cowden, MA, AT, LPCC-S, Patient Advocacy Director of the Meredith A. Cowden Foundation discuss graft-versus-host-disease (GVHD), a rare disease that commonly impacts allogeneic (meaning cells that come from a donor) blood and marrow transplant recipients, the inaugural GVHD Day on Feb 17, 2023, the importance of bringing attention to this rare disease, and a new website for the GVHD community to access a variety of educational resources and support tools...
2023-03-09
07 min
ASTCT Talks
MRD in Relation to Transplantation and Cell Therapy
In this latest episode of ASTCT Talks, Dr. Andrés Gómez De León sits down with Dr. Aaron Logan to discuss development of current techniques for quantifying measurable residual disease (MRD) in acute lymphoblastic leukemia and MRD's relation to transplantation and cell therapy. They discuss the concept of MRD and its relevance in the treatment of leukemia as a prognostic marker and to help guide clinical decision-making, as well as the future of MRD research and more. About Dr. Andrés Gómez De León Dr. Andrés Gómez De León (@GomezDLeo...
2023-02-07
1h 00
ASTCT Talks
The Winter "Tridemic" in Cellular Therapy
In this latest episode of ASTCT Talks, Dr. Firas El Chaer talks with Dr. Alpana Waghmare and Dr. Michael Ison to discuss the winter “Tridemic,” which includes COVID, flu and respiratory syncytial virus (RSV). They discuss the diagnostic and treatment approaches for the Tridemic in recipients of hematopoietic cell transplantation and cellular therapy, examine the precautions and best practices for recipients of hematopoietic cell transplantation and more. This podcast was recorded on December 21, 2022. About Dr. Firas El Chaer Firas El Chaer, MD, (@FirasElChaer) is an assistant professor of medicine who specializes in hematology and oncology. He c...
2023-01-11
49 min
ASTCT Talks
Titans of Transplant: Susan Slater, MN, FNP-BC
In the next installment of ASTCT’s Titans of Transplant series, Susan Slater, nurse practitioner and recipient of the Best APP Abstract Award at the 2016 BMT Tandem meetings and the 2020 APP SIG Lifetime Achievement Award, is interviewed by Dr. Jennifer Saultz, Assistant Professor of Medicine at Oregon Healthy & Science University and a member of the Adult Transplant and cellular therapy team. About Susan Slater Susan Slater, MN, FNP-BC is an Assistant Professor of Medicine in the Knight Cancer Institute at Oregon Health & Science University. She has 25 years’ experience as nurse practitioner caring for patients with hema...
2022-12-07
20 min
ASTCT Talks
Monkeypox in HCT and CAR T
In this latest episode of ASTCT Talks, Dr. Steven Pergam talks with Dr. Amy Spallone and Dr. Emily Ford to discuss Monkeypox in HCT and CAR T. They cover the basics of Monkeypox, risk factors for Monkeypox among patients, presenting symptoms for Monkeypox, vaccines for Monkeypox and more. About Dr. Steven Pergam Dr. Steven Pergam (@PergamIC) is an Infectious Diseases Physician and Professor at the Fred Hutchinson Cancer Center in the Division of Vaccine and Infectious Diseases. He is also the Infection Prevention Director of the Cancer Center, and a faculty member of the University o...
2022-10-26
47 min
ASTCT Talks
Titans of Transplant: Dr. John F. DiPersio
In the next installment of ASTCT’s Titans of Transplant series, Dr. John. F. DiPersio, an internationally recognized leader in hematopoietic stem cell transplantation and acute leukemia and past president of ASTCT (2019) is interviewed by Dr. Roman Shapiro. About Dr. John F. DiPersio John F. DiPersio, MD, PhD is deputy director at Alvin J. Siteman Cancer Center, director at Center for Gene and Cellular Immunotherapy and chief of the division of oncology at Washington University School of Medicine in St. Louis and the Virginia E. and Samuel J. Golman professor of medicine. His research focuses on...
2022-10-10
40 min
ASTCT Talks
Celebrating Advocacy Efforts, Overcoming Barriers and Addressing Inequity in Cellular Transplantation
In this latest episode of ASTCT Talks, we celebrate National Hispanic Heritage Month as Dr. Jennifer Saultz talks with Dr. Eneida Nemecek to highlight her work and share her advocacy, passion and journey to becoming a medical director of clinical research. She explains her experiences as a Latina woman in the field of cellular therapy and transplantation, barriers Hispanic and marginalized groups face in cellular transplantation, inclusivity efforts for health equity, the value of mentor and sponsorship and more. About Dr. Jennifer Saultz Dr. Jennifer Saultz is an Assistant Professor of Medicine at Oregon Healthy...
2022-09-28
36 min
ASTCT Talks
Titans of Transplant: Dr. Rainer Storb
In the next installment of ASTCT’s Titans of Transplant series, Dr. Rainer Storb, one of the pioneers who established allogeneic, or donor, blood stem cell transplantation as a cure for diseases like leukemia and aplastic anemia, is interviewed by Dr. Masumi Ueda. About Dr. Storb Rainer Storb, MD, serves as Professor and Head of Transplantation Biology Program Clinical Research Division at Fred Hutch. About Dr. Ueda Masumi Ueda, MD, serves as Associate Professor in the Clinical Research Division of the Fred Hutchinson Cancer Center and the Division of Medical Oncology at...
2022-09-13
42 min
ASTCT Talks
Titans of Transplant: Dr. Adriana Seber
In the next installment of ASTCT’s Titans of Transplant series, Dr. Hema Rangarajan, an oncologist at Nationwide Children’s Hospital and a member of the ASTCT Content Committee, speaks with Dr. Adriana Seber, who is a professor of medicine at the University of Miami and the Kalish Family Chair and Chief of Division of Transplantation and Cellular Therapy at Sylvester Comprehensive Cancer Center and Vice-President of the Brazilian BMT Society. The Titans of Transplant series seeks to recognize, celebrate and chronicle the physicians, researchers, pharmacists, nurses, social workers and more who were on the frontlines of the...
2022-07-12
40 min
ASTCT Talks
Finding Affordable and Accessible Hematopoietic Cell Transplants
In this latest episode of ASTCT Talks, Dr. Andrés Gómez De León, a physician at the Universidad Autónoma de Nuevo León Hematology Service in Monterrey, Mexico, and Dr. Cristóbal Frutos, who is the Coordinator for the Bone Marrow transplant Unito the Hospital Central Instituto de Previsión Social in Asunción Paraguay, discuss the current state of transplant activities and the importance of having access to cell therapies worldwide. Dr. Frutos presented on this topic during the 2022 Tandem Meetings of ASTCT & CIBMTR.
2022-06-29
53 min
ASTCT Talks
Titans of Transplant: Dr. Krishna Komanduri
In the next installment of ASTCT’s Titans of Transplant series, Dr. Rahul Banerjee, Advanced Fellow, BMT/CAR-T Therapy, with the Division of Hematology/Oncology in the Department of Medicine at the University of California San Francisco, speaks with Dr. Krishna Komanduri, who is a professor of medicine at the University of Miami and the Kalish Family Chair and Chief of Division of Transplantation and Cellular Therapy at Sylvester Comprehensive Cancer Center. The Titans of Transplant series seeks to recognize, celebrate and chronicle the physicians, researchers, pharmacists, nurses, social workers and more who were on the frontlines of...
2022-04-04
41 min
ASTCT Talks
Managing COVID-19 in Transplant Patients
In the latest episode of ASTCT Talks, Dr. Zainab Shahid, internist in the hematology department of the Levine Cancer Institute Morehead in Charlotte, North Carolina, leads a conversation around ongoing clinical challenges regarding management of COVID-19 in transplant cellular therapy recipients. Dr. Shahid is joined by some of the foremost experts in infectious disease and transplant patients: Dr. Esther Babady is chief of the clinical microbiology service at Memorial Sloan Kettering Cancer Center; Dr. Mini Kamboj is chief medical epidemiologist for infection control at Memorial Sloan Kettering Cancer Center; and Dr. Camille Kotton is the Clinical Director, Transplant...
2022-03-16
50 min
ASTCT Talks
Titans of Transplant: Dr. Gregorio Jaimovich
In the second installment of ASTCT’s Titans of Transplant series, Dr. Andrés Gómez De León, physician with the Universidad Autónoma de Nuevo León Hematology Service in Monterrey, Mexico, speaks with Dr. Gregorio Jaimovich, who is the director of the bone marrow transplantation programs of the Favaloro University Hospital and the Anchorena Hospital in Buenos Aires, Argentina. The Titans of Transplant series seeks to recognize, celebrate and chronicle the physicians, researchers, pharmacists, nurses, social workers and more who were on the frontlines of the early days of transplant.
2022-02-15
27 min
ASTCT Talks
Titans of Transplant: Dr. Mary Horowitz
In the first episode of ASTCT’s Titans of Transplant series, Dr. Jennifer Holter-Chakrabarty, physician with The University of Oklahoma Health and professor of medicine in hematology/oncology, speaks with Dr. Mary Horowitz, whose credentials include professor and deputy cancer center director at the Medical College of Wisconsin; the Robert A. Uihlein, Jr. Chair in hematologic research; associate director of genomics; and scientific director emeritus of CIBMTR. The Titans of Transplant series seeks to recognize, celebrate and chronicle the physicians, researchers, pharmacists, nurses, social workers and more who were on the frontlines of the early days of tr...
2022-01-24
37 min
ASTCT Talks
A Deep Dive On Early Time-to-Toci
Join Dr. Rahul Banerjee, Advanced Fellow of BMT / CAR T Therapy in the Department of Medicine at the University of California San Francisco, and Dr. Nina Shah, Associate Professor in the Department of Medicine at UC San Francisco, as they discuss their paper “Early Time-to-Tocilizumab after B Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy in Myeloma.” The paper was co-authored by Drs. Shah and Banerjee, along with several colleagues, and was published in ASTCT’s Transplantation and Cellular Therapy Journal in March.
2021-07-29
25 min
ASTCT Talks
Advancements in Immunotherapies with Dr. DiPersio
This episode of ASTCT Talks features a recently recorded conversation with Dr. John DiPersio, a Bone Marrow Transplant Specialist and Medical Oncologist at the Siteman Cancer Center at the Washington University School of Medicine, and a past president of ASTCT. We discuss emerging therapies to treat AML, advancements in immunotherapies, and much more.
2021-06-10
28 min
ASTCT Talks
Outpatient Haploidentical Stem Cell Transplantation
In this episode of ASTCT Talks, Dr. Andrés Gómez De León, physician at the Universidad Autónoma de Nuevo León Hematology Service in Monterrey, Mexico, and Dr. Perla Colunga, who is one of the specialist physicians in the hematology service of UANL, discuss their paper “Outpatient Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamide Is Safe and Feasible,” which was published in the Transplantation and Cellular Therapy journal in December.
2021-05-25
23 min
ASTCT Talks
A Deep Dive on Chronic GVHD
In this episode of ASTCT Talks, we’re joined by Steven Pavletic, MD, MS, Senior Clinician, Immune Deficiency Cellular Therapy Program, National Cancer Institute Center for Cancer Research; and Kirk Schultz, MD, Professor, University of British Columbia BC Children’s Hospital. Our conversation spans all-things chronic GVHD, including the latest research and discussions coming out the Chronic GVHD Consensus Conference, held in November 2020.
2021-03-24
35 min
ASTCT Talks
The Role of MRD in Multiple Myeloma
In this episode of ASTCT Talks, we sit down with Parameswaran Hari, MD, MCRP to discuss the role of minimal residual disease in multiple myeloma. Hari, the Armand J. Quick/William F. Stapp Professor of Hematology and the Chief of the Division of Hematology/Oncology at the Medical College of Wisconsin, said advances in MRD testing signals improvement in progression-free survival in multiple myeloma. While this is good news for clinicians, there’s still a ways to go to ensure MRD testing is being understood correctly.
2020-12-10
17 min
ASTCT Talks
MRD Negativity and Lenalidomide Maintenance Therapy: The Possible Next Chapter in Multiple Myeloma Care
On this episode of ASTCT Talks, we sit down with Dilan Patel, MD, advanced BMT fellow at Washington University School of Medicine in St. Louis. Patel was the lead author on a paper that explored minimal residual disease negativity and lenalidomide maintenance therapy, and how those were associated with superior survival outcomes for patients with multiple myeloma.
2020-12-02
16 min
ASTCT Talks
Dr. Lia Gore Discusses Bispecific T-Cell Engagers in Pediatric ALL Research
In this episode of ASTCT Talks, we sit down with Dr. Lia Gore, professor of pediatrics in hematology-oncology and bone marrow transplantation and co-director of the Developmental Therapeutics Program at the University of Colorado Cancer Center. Dr. Gore was the co-investigator on the AALL1331 trial and led the preceding open-label Phase 1–2 trial, AALL1121, which was the first to demonstrate the antileukemic activity of single-agent blinatumomab in children with relapsed or refractory B-ALL. We talk about her research and how the trial signals future research of bispecifics in pediatric care.
2020-11-12
26 min
Ligne de MIR
Ligne de MIR n°59 – Le Professeur Zafrani nous parle des CAR T cells
Le Professeur Lara Zafrani, PU-PH dans le service de Médecine Intensive Réanimation de l’Hôpital Saint-Louis à Paris, nous parle CAR T cells.Aucun lien d’intérêt déclaré.Sommaire :• Qu'est ce que sont Les CAR T cells ?• Quelles sont les complications des CAR T cells que l'on peut voir en réanimation ?• Quelle est la prise en charge de ces complications ?Références : Chimeric antigen receptor T cells for sustained remissions in leukemia.Maude SL, Frey N, Shaw PA, Aplenc R, Barrett DM, Bunin NJ, Chew A,Gonzalez VE...
2020-06-01
08 min