Shows
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessWhat are flashback hallucinations? Exploring HPPD - With Dr Torsten Passie and Ben Clayden - The Psychedelic Frontiers Podcast Episode 10 The latest episode of the Psychedelic Frontiers Podcast focuses on Hallucinogen Persisting Perception Disorder (HPPD) where individuals experience persistent visual hallucinations or perceptual distortions after previous use with drugs, including but not limited to psychedelics such as LSD. HPPD is rarely encountered in clinical settings, and its aetiology is poorly understood. Wide variations across participants are seen in symptoms, frequency and treatment-efficacy in this mysterious disorder, and it's clear more research is needed to identify its risk factors and underlying mechanisms. Today on the Psychedelic Frontiers Podcast, we’ll Torsten and Ben discuss what’s currently understood about HPPD, and r...2024-02-081h 03
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessPossible Complications in Psychedelic Therapy with Dr Torsten Passie - Episode 9 of the Psychedelic Frontiers PodcastIn recent years, psychedelics have been shown increased interest as a possible therapeutic agent for the treatment of various mood and mental health disorders, ranging from PTSD and Major Depressive Disorder to Anorexia and End of Life Associated Anxiety. Institutions all over the world are running clinical trials, with many producing promising results, however not without complications and challenges. Today on The Psychedelic Frontiers Podcast, we’ll discuss Psychedelic Assisted Therapies. For which disorders does this emerging treatment show the most promise for? What are the current methodological issues and challenges facing researchers studying this treatment? How generalizable are the re...2023-09-1251 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessThe History of MDMA - With Dr Torsten Passie and Ben Clayden - The Psychedelic Frontiers Podcast Ep.8Recent statistics have shown that more than 100 million people on the planet have used MDMA, making it the second most popular drug worldwide. Commonly reported effects include altered sensations, increased energy, empathy and pleasure. Since its discovery, MDMA has garnered significant interest both from recreational users as a party drug, as well as from the medical and therapeutic communities as a possible therapeutic tool. Today, on the Psychedelic Frontiers podcast (formerly the Psychedelics in Medicine Podcast), we’ll take a deep dive into the rich history of MDMA.Dr Passie is a German psychiatrist, professor at Hannover Me...2023-06-1550 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessLow Dose Psycholytic Therapy: A neglected approach - The Psychedelics in Medicine Podcast with Dr. Torsten Passie and Ben ClaydenThe phrase ‘psycholytic therapy’ was coined by Ronald A. Sandison, literally meaning soul-dissolving. In contrast to psychedelic therapy, psycholytic therapy places more emphasis on the psychotherapy than the substance. It typically consists of a low-to-medium dose of a psychedelic compound alongside more therapy sessions than its counterpart.In this month’s episode of the Psychedelics in Medicine Podcast (PiMPOD), Dr Torsten Passie and Ben Clayden discuss psycholytic therapy. What is the history of substance assisted therapies? What are its differences to psychedelic therapy? Has it shown therapeutic relevance and efficacy? These and much more our discussed in today...2023-02-2848 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessFirst Hand Experience in Psychedelic Therapists - PiMPOD E6In this month’s episode of the Psychedelics in Medicine Podcast (PiMPOD), Dr Torsten Passie and Ben Clayden discuss Self-experimentation with psychedelic substances. What is the history of psychedelic self-experimentation, why is self-experimentation important for therapists conducting psychedelic assisted psychotherapy, which aspects of the trip are particularly important, and what ethical issues may arise if psychedelic therapists are required to take psychedelics before finishing their training? All of these questions and more are covered in our first episode of 2023Dr Passie is a German psychiatrist, professor at Hannover Medical School and is an expert in altered states of...2023-01-3050 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessKetamine: Anaesthetic, Psychedelic or Antidepressant?Ketamine: Anaesthetic, Psychedelic or AntidepressantIn this month’s episode of the Psychedelics in Medicine Podcast (PiMPOD), Dr Torsten Passie and Ben Clayden discuss Ketamine, a unique anaesthetic which can produce dissociative and even hallucinogenic states. We’ll take a look at Ketamine’s history, variations in its use across cultures, its pharmacology and differences between its two enantiomers, before finally discussing its potentially as a rapidly acting antidepressant. Dr Passie is a German psychiatrist, professor at Hannover Medical School and is an expert in altered states of consciousness. Torsten has performed clinical and experimental studie...2022-12-2952 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessLSD Derivatives: What causes the effects of a drug? - PiMOPOD4 with Dr Torsten Passie and Ben ClaydenIn this month’s episode of the Psychedelics in Medicine Podcast (PiMPOD), Dr Torsten Passie and Ben Clayden discuss LSD Derivatives, A nearly identical molecule with just a few differences. We discuss multiple derivatives of LSD, including LSA, 2-Bromo-LSD (BOL-148), 1P-LSD and use them in combination to better understand the intricacies of the neural mechanisms of LSD, and how slight changes to a molecules three-dimensional structure can completely alter their effects, through differences in ligand-receptor binding.We then look at a study using a non-hallucinogenic version of LSD, BOL-148 as preventative treatment for cluster headache, discussing its im...2022-11-0453 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessThe Science of Microdosing Psychedelics with Dr Torsten Passie - PiMPOD3In this months episode of PiMPOD, I, Ben Clayden am once again joined with Dr Torsten Passie. Today we’ll take a look into the science of microdosing psychedelics.We discuss the background history and science before taking a look at two recent papers looking at the effects of microdosing psilocybin. We take a look into the placebo effect and the role of expectation and finally, Torsten shares his thoughts on methodological approaches to avoiding participants breaking blind, and what a useful placebo may be for microdosing.Dr Torsten Passie is a German psychiatrist, professor at...2022-10-0741 min
The Drug Science Podcast72. The Student Society Network with Libby Furminger and Ben ClaydenLibby and Ben are third-year students from Swansea University and the University of York, who are deeply interested in the use of psychedelics in medicine and drug policy. At their universities, they are presidents of their respective Psychedelics in Medicine societies which raise awareness on the therapeutic potential of psychedelic drugs among fellow students. Tune in to the episode to find out about their journeys into the world of Drug Science and how to get involved yourself! Get in touch with the Student Society Network! Find out more about the Drug Science Student Soc...2022-09-1437 min
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessLSD: Stigma, Synthesis and Science with Dr Torsten Passie & Ben Clayden - PiMPOD2In this months episode of PiMPOD, I, Ben Clayden am once again joined with Dr Torsten Passie, this time to discuss Lysergic Acid Diethylamide (LSD), the most researched drug in history!The podcast begins with the fantastic discovery story of LSD and its psychedelic effects by Albert Hoffman, then discusses the early research conducted, including some of the less ethical studies in the 60's like the well known MK-ULTRA.We then take a dive into the psychological effects, neurobiology, and pharmacology of LSD, after which we discuss the applications of LSD assisted psychotherapy....2022-09-101h 05
Psychedelic Frontiers: Bridging Science, Medicine and ConsciousnessHeroin Assisted Treatment with Dr Torsten Passie - PiMPOD1Heroin Assisted Therapy has shown large promise in helping 'heroin using humans' improve both in mental and physical health, social integration, crime reduction and decrease of opioid use according to a large study conducted in Germany between 2002-2004.On the first episode of PiMPOD I discuss the history, implications and future of Heroin Assisted Treatment with Dr Torsten Passie, Psychiatrist, leading expert on altered states of consciousness and professor at Hannover Medical School.2022-08-0353 min