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BioTech BreakdownBioTech BreakdownSpinal Muscular Atrophy and ASO TherapyJoin me as we explore the progression of Spinal Muscular Atrophy and understand the mechanisms behind our current treatment: ASO therapy. Transcript: What’s up people and welcome to Biotech Breakdown, a platform, dedicated to simplifying cutting-edge biomedical innovations and fostering a passion for biotechnology within all. I’m your host Raghav and if you haven’t already smashed that follow button, go ahead and do that now to show your support. Anyways, if you’re ready, I’m ready let’s break down Spinal Muscular Atrophy and ASO therapy.  Alright, so w...2024-07-1705 minBioTech BreakdownBioTech BreakdownPROTAC - A Protein Purge SystemJoin me as we dive into the mechanisms behind PROTACs, a system to target and degrade proteins specifically!2024-06-2605 minBioTech BreakdownBioTech BreakdownBeyond Acute Myeloid LeukemiaJoin me as we dive into the deadly cancer that inhibits immune function - Acute Myeloid Leukemia as well as potential cures for this condition. Specifically, Anti-Body Drug Conjugates. Sources: https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/about-acute-myeloid-leukaemia https://medlineplus.gov/acutemyeloidleukemia.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639599/ https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml https://www.cancer.org/cancer/types/acute-myeloid-leukemia/about/what-is-aml.html https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/treating-aml/decisions-about-your-treatment 2024-06-1005 minBioTech BreakdownBioTech BreakdownHyperbaric Oxygen Therapy - A Cure for Necrotizing FasciitisJoin me as we dive into the mechanisms behind the "flesh eating disease", Necrotizing Fasciitis, and our modern treatment for this painful disease - Hyperbaric Oxygen Therapy. Sources: https://pubmed.ncbi.nlm.nih.gov/2237764/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516968/ https://www.sciencedirect.com/topics/medicine-and-dentistry/necrotizing-fasciitis https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/necrotizing-fasciitis https://my.clevelandclinic.org/health/diseases/23103-necrotizing-fasciitis2024-05-1905 minBioTech BreakdownBioTech BreakdownApproaches to Alzheimer'sJoin me as we dive into the mechanism behind Alzheimer's disease and different approaches in development to treat this condition! Sources: 1) DZNE Abt. fuer Presse- und Oeffentlichkeitsarbeit. “Tau.” DZNE, www.dzne.de/en/news/background/tau/. Accessed 13 Apr. 2024. 2) E;, Wegmann S;Biernat J;Mandelkow. “A Current View on Tau Protein Phosphorylation in Alzheimer’s Disease.” Current Opinion in Neurobiology, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/33892381/#:~:text=Elevated%20phosphorylation%20and%20aggregation%20of,modifications%20in%20the%20disease%20context. Accessed 13 Apr. 2024. 3) Schub...2024-04-1305 minBioTech BreakdownBioTech BreakdownElectroconvulsive Therapy - Medication for Mental DisordersJoin me as we take an exciting look of biomedical applications in the field of psychology. Today we'll explore Electroconvulsive therapy and its ability to treat certain mental disorders.2024-03-2305 minBioTech BreakdownBioTech BreakdownCrackinCancer 3 - Oncolytic Viral TreatmentJoin me as we expand our knowledge on the ongoing research in finding cures as well as treatments for cancer. Today, we explore the possibility of using a virus to destroy cancer cells.2024-03-1005 minBioTech BreakdownBioTech BreakdownCrackinCancer 2 - TCR TherapyJoin me as we continue our series dedicated to exploring upcoming cures and treatments for cancer. Today we discuss the inner mechanisms behind the exciting innovation of TCR Therapy!2024-03-0205 minBioTech BreakdownBioTech BreakdownCrackinCancer Part 1 - TIL TherapyJoin me as we start off a brand new series dedicated to unveiling the mechanisms behind some of the latest and in development treatments and cures for cancer!2024-03-0205 minBioTech BreakdownBioTech BreakdownAdvancements with Single Cell GenomicsJoin me as we dive into the upcoming field of single cell genomics and its ability to leave an impact on the biotechnology field.2024-02-1704 minBioTech BreakdownBioTech BreakdownTackling Thyroid DiseaseJoin me as we learn about how the thyroid gland operates and the various conditions related to it! To learn more about the thyroid gland - https://my.clevelandclinic.org/health/body/23188-thyroid Sources: - Cleveland Clinic medical. “Thyroid: What It Is, Function & Problems.” Cleveland Clinic, my.clevelandclinic.org/health/body/23188-thyroid. Accessed 14 Jan. 2024.  Curtis, Lindsay. “Is Hypothyroidism Genetic?” Verywell Health, Verywell Health, 21 Nov. 2022, www.verywellhealth.com/hypothyroidism-genetic-5323760#:~:text=Symptoms%20include%20cold%20intolerance%2C%20depression,family%20history%20increases%20your%20risk. 2024-01-1406 minBioTech BreakdownBioTech BreakdownAntiretroviral Medicine - A treatment for HIVJoin me as we explore the workings of our modern day treatment for HIV - Antiretroviral medicines!2023-12-3004 minBioTech BreakdownBioTech BreakdownA Cure for Cancer? - CAR T - Cell TherapyJoin me as we dive into the mechanisms of CAR T - Cell Therapy, a revolutionary treatment capable of curing cancer!2023-11-2104 minBioTech BreakdownBioTech BreakdownControlling Tech with our Mind?Join me as we dive into the intricate mechanism behind BCI or Brain - Computer Interface and explore their applications in our day to day life2023-11-1304 minBioTech BreakdownBioTech BreakdownCloning - More of Me?Join me as we dive into the mechanisms behind the exciting possibility of cloning and comprehend whether more me is good or not so good.2023-11-0504 minBioTech BreakdownBioTech BreakdownGateway to the Future Part 3 - DNA BiosensorsJoin me as we further our knowledge on biosensors and dive into the mechanism and possibilities of DNA biosensors. 2023-11-0404 minBioTech BreakdownBioTech BreakdownGateway to the Future Part 4 - ImmunosensorsJoin me as we dive into a specific branch of biosensors - Immunosensors! Ranging from the way the immune system works to how we are capable of using it to diagnose diseases!2023-10-0205 minBioTech BreakdownBioTech BreakdownGateway to the Future 2 - Enzymatic BiosensorsJoin us as we dive into the intricate mechanism of the enzymatic biosensor and discuss its advantages and disadvantages. This is Part 2 of the biosensors series.2023-09-0404 minBioTech BreakdownBioTech BreakdownGateway to the Future - Biosensors Part 1Join me as I dive into the captivating mechanism of a general biosensor as well as it's applications. Remember, this is part 1, there's more on the way.2023-08-2005 minBioTech BreakdownBioTech BreakdownThe One for All CRISPR VaccineJoin me as I dive into my idea of a Generational One for All Vaccine that employs CRISPR - Cas9. 2023-07-3105 minBioTech BreakdownBioTech BreakdownCRISPR - Cas9, The Prince of BiotechnologyJoin me as we dive into the mechanisms of CRISPR as well as the context as to how Jennifer Doudna and Emmanuel Charpentier invented it.2023-07-2204 minBioTech BreakdownBioTech BreakdownOrgans on a Chip - An ethical laboratory future?Join me as I explain the mechanism behind the Organs on a Chip model and express my views on its potential power to replace one of mankind's most inefficient and unethical methods - animal testing.2023-07-1504 minBioTech BreakdownBioTech BreakdownmRNA VaccinesJoin me as I explain the context of mRNA and about the mechanism of the mRNA vaccines as well as its pros and cons.2023-07-0803 minBioTech BreakdownBioTech BreakdownThe StartIntroducing myself and what we will be covering in our podcast. Make sure to tune in for our next week's episode on mRNA vaccines.2023-06-2500 min