Shows
Longevity Roadmap168: Best of 2025Over the past year, we covered a wide range of ground—from clinicians working directly with patients to top scientists studying the underlying biology of aging. This episode is a chance to look back at some of the more interesting conversations we had on Longevity Roadmap in 2025. Looking ahead, there's no sign that the pace is slowing. In longevity, it often feels like every year brings another set of breakthroughs, and 2026 is shaping up to be a big one. One of the most important trends to watch is the increasing role of artificial intelligence in medicine, particularly in...
2025-12-2922 minLongevity Roadmap167: Why Bats Don't Age and Why You Should Care with Dr. Emma TeelingAging is usually linked to size, metabolism, and inevitable decline—but bats defy all three. In this episode, Dr. Buck Joffrey speaks with Dr. Emma Teeling about why bats are rewriting the rules of longevity science. The discussion explores how bats live far longer than expected for their size while avoiding cancer, immune dysfunction, and chronic inflammation. They examine how stable telomeres, enhanced DNA repair, and tightly controlled immune responses allow bats to age slowly despite extreme metabolic demands. Watch the full episode to understand why bat biology is reshaping how researchers think ab...
2025-12-2237 min
Wealth Formula by Buck Joffrey537: Markets Do Not Behave Like Saber-Toothed TigersYou know, the longer I’ve been an investor, the more I realize this simple truth: the biggest threat to your wealth isn’t the market… it’s your own brain.
We’re all wired the same way—with instincts that were fantastic for avoiding saber-toothed tigers but are absolutely terrible for making good financial decisions.
Take something simple like a marathon. If I asked you to predict next year’s top finishers, you’d look at last year’s results. That works. Human performance doesn’t flip upside down in twelve months. The best runners tend to stay...
2025-12-1535 minLongevity Roadmap166: BioXcellerator - The Cutting Edge of Stem Cell TherapyLongevity medicine is moving beyond symptom management—and regenerative therapies are forcing a deeper look at how healing actually works. In this episode, Dr. Buck Joffrey speaks with the team at BioXcellerator about what separates rigorous regenerative medicine from hype-driven shortcuts. The conversation focuses on why stem cells aren't about "replacing" tissue, but about directing the body's own repair systems through immune signaling, inflammation control, and cellular communication. Drawing from Buck's own experience receiving treatment at BioXcellerator, the discussion unpacks why cell source, processing, viability, and delivery fundamentally shape outcomes. They break down the...
2025-12-1546 minLongevity Roadmap164: Young Blood Can Rejuvenate Old Brains with Dr. Tony Wyss-CorayIn this episode, we are joined by Dr. Tony Wyss-Coray to discuss his groundbreaking research on brain resilience and aging. He explains how systemic factors, particularly proteins in the blood, influence cognitive function and the aging process. The discussion covers the role of proteomics, machine learning, and the potential of parabiosis and plasma infusions in developing therapies for age-related diseases like Alzheimer's. Dr. Wyss-Coray emphasizes the importance of understanding the biological markers of aging and resilience to create targeted interventions for healthier aging. Learn more about Dr. Wyss-Coray: https://b...
2025-12-0134 minLongevity Roadmap163: How Mitochondrial Decline Drives Brain Aging with Dr. Francisco Gonzalez-LimaIn this episode, we are joined by Dr. Francisco González-Lima to delve into the metabolic mechanisms that drive brain aging and cognitive decline. He begins by outlining how reductions in cytochrome oxidase activity, disruptions in oxidative phosphorylation, and the accumulation of mitochondrial mutations progressively impair neuronal energy metabolism. These metabolic deficits, he explains, often emerge long before the structural abnormalities associated with Alzheimer's disease. Building on this foundation, the conversation examines how reactive oxygen species, mitochondrial inefficiency, and altered cortical oxygen utilization contribute to diminished cognitive resilience over time. Dr. González-Lima highlights why th...
2025-11-2459 minLongevity Roadmap162: The Habits of Healthy Aging with Dr. Kate WolinWe are joined by behavioral epidemiologist Dr. Kate Wolin to unpack why so many health interventions collapse outside the lab—and what actually drives lasting change in the real world. From frictionless habit design and daily self-monitoring to movement, sleep, and the muscle-preserving realities of GLP-1s, she reveals the behavioral strategies that truly move the needle on long-term metabolic and overall health. Watch the full episode to learn how evidence-based behavior science can transform your healthspan. Learn more about Dr. Kate Wolin: https://drkatewolin.com/ - Do...
2025-11-1725 minLongevity Roadmap161: The Future of Tissue Regeneration with Dr. Jennifer ElisseeffIn this episode, we are joined by Dr. Jennifer Elisseeff to discuss the evolving field of tissue engineering and its applications in regenerative medicine. She explains the shift from using stem cells to focusing on immune cells for tissue repair, the challenges of regenerating cartilage, and the importance of vascularity in tissue health. The discussion also covers the impact of aging on tissue repair, the role of senescent cells, and the future of personalized medicine in tissue engineering. Dr. Elisseeff emphasizes the need for innovative approaches and the integration of immunotherapies to enhance...
2025-11-1030 minLongevity Roadmap160: Molecular Secrets of Aging Told Through Worms with Dr. Heidi TissenbaumDr. Heidi Tissenbaum, a molecular geneticist at UMass Chan Medical School, joins Dr. Buck Joffrey to explore what C. elegans worms have revealed about the biology of aging. She explains how these simple organisms helped uncover key longevity pathways—like insulin/IGF-1 signaling and sirtuins—that also exist in humans. The conversation dives into the balance between stress and resilience, the role of IGF-1 in muscle health and lifespan, and why she believes true longevity breakthroughs will require understanding how the body's systems communicate as a whole. Learn more about Dr. Heidi Tissenbaum:
2025-11-0332 minLongevity Roadmap159: How DNA Mutations and Epigenetic Drift Cause Aging with Prof. Jan VijgThis week, Professor Jan Vijg joins us to discuss the intricate relationship between DNA mutations, epigenetic drift, and aging. He explains the differences between mutations and epigenetic changes, the role of environmental factors, and the potential for reversing epigenetic changes. The conversation also touches on the implications of somatic mutations and the future of longevity research, particularly in relation to DNA repair mechanisms. Learn more about Professor Jan Vijg: https://einsteinmed.edu/faculty/11318/jan-vijg - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://r...
2025-10-2733 minLongevity Roadmap158: Sitting Is the New Smoking with Dr. Keith DiazIn this episode, we are joined by Dr. Keith Diaz to discuss the significant health risks associated with prolonged sitting, likening it to smoking in terms of its dangers. He emphasizes the importance of regular movement, introducing the concept of 'movement snacks'—short bursts of activity that can mitigate the negative effects of sitting. We also cover the physiological mechanisms behind how movement affects blood sugar levels and inflammation, as well as insights from blue zones where people naturally incorporate more movement into their daily lives. Dr. Diaz advocates for personalized movement recommendations to...
2025-10-2025 minLongevity Roadmap157: The Role of Surgery in Diabetes and Obesity with Dr. Mitchell RoslinIn this episode, we are joined by Dr. Mitchell Roslin to discuss the complexities of obesity. We explore the role of GLP-1 medications in weight management, the evolution of bariatric surgery, and the innovative SIPS procedure. Dr. Roslin emphasizes that obesity is not merely a result of poor lifestyle choices but involves intricate biological and hormonal mechanisms. He also highlights the importance of functional assessments in determining appropriate treatment for obesity, advocating for a more systematic approach to obesity management. Learn more about Dr. Mitchell Roslin: https://faculty.medicine.hofstra.edu/4990-m...
2025-10-1341 minLongevity Roadmap156: Investing in the Business of Aging with Dr. Karl PflegerIn this episode, Dr. Karl Pfleger joins us to discuss the evolving landscape of longevity research and investment. He emphasizes the shift from disease-specific approaches to understanding aging as a multifaceted process that underpins many chronic diseases. Dr. Pfleger outlines his investment strategies in the aging biotech sector, highlighting the importance of addressing various sub-pathologies of aging. He also discusses the concept of longevity escape velocity, the challenges of proving longevity therapies, and the role of aging clocks in research. Learn more about Dr. Karl Pfleger: https://x.com/k...
2025-10-0631 minLongevity Roadmap155: Can Psilocybin Extend Cellular Lifespan? with Dr. Louise HeckerIn this episode, Dr. Louise Hecker joins us to discuss her groundbreaking research on psilocybin, exploring its potential to extend cellular lifespan and improve health outcomes in aging. We delve into the mechanisms behind psilocybin's effects, findings from animal studies, and the challenges faced in conducting research on this Schedule I substance. Dr. Hecker emphasizes the importance of understanding optimal dosing protocols and safety considerations for future applications of psilocybin in geroprotection. Learn more about Dr. Louise Hecker: https://med.emory.edu/directory/profile/?u=LHECKER - ...
2025-09-2927 minLongevity Roadmap154: Is Telomere Length Shortening the Master Switch of Aging? with Dr. Bill AndrewsIn this episode, Dr. Bill Andrews joins Dr. Buck Joffrey to discuss the critical role of telomeres and telomerase in aging and cellular health. He explains how telomeres shorten with each cell division, leading to aging and cellular senescence. Dr. Andrews emphasizes the importance of inducing telomerase to potentially reverse aging and shares insights from his research on telomerase inducers. He also addresses the challenges in longevity research, the relationship between telomeres and the hallmarks of aging, and the potential of gene therapy. The conversation concludes with a discussion on lifestyle...
2025-09-2247 minLongevity Roadmap153: T Cells, Aging, and Extreme Life Extension with Dr. Derya UnutmazDr. Derya Unutmaz joins Dr. Buck Joffrey to discuss the critical role of T cells in the immune system, their changes with aging, and the implications for chronic diseases. He emphasizes the importance of thymus regeneration and the microbiome's influence on health. The discussion also covers advancements in engineering immune cells for cancer treatment and the potential of AI in revolutionizing aging research and drug discovery. Unutmaz expresses optimism about the future of aging research, highlighting the need for a shift in how aging is perceived in the medical community. Learn...
2025-09-1550 minLongevity Roadmap152: The Role of Vitamin A in Brain Health with Prof. Peter McCafferyIn this episode, Professor Peter McCaffery joins Dr. Buck Joffrey to discuss the multifaceted role of Vitamin A in brain health, particularly its function as a signaling molecule that influences neuroplasticity and cognitive functions. He elaborates on the challenges of Vitamin A supplementation, especially in aging populations, and the implications of retinoic acid signaling in neurodegenerative diseases like Alzheimer's. The discussion also touches on the importance of skin health in the context of systemic aging and the potential for targeted therapies to enhance Vitamin A signaling without the risks associated with traditional supplementation. ...
2025-09-0836 minLongevity Roadmap151: Does Astaxanthin Increase Longevity? with Dave WatumullIn this episode, Dave Watumull joins Dr. Buck Joffrey to discuss the benefits and mechanisms of astaxanthin, a powerful antioxidant and anti-inflammatory compound. He explains its role in longevity, particularly through the Interventions Testing Program (ITP), where astaxanthin was shown to extend lifespan in male mice by 12%. The discussion also covers the safety profile, bioavailability, and clinical studies demonstrating cardiovascular benefits. Gender differences in efficacy are explored, along with practical advice on dosage and where to find astaxanthin products. Learn more about AX3: https://ax3.life/ -
2025-09-0141 minLongevity Roadmap150: The Microbiome's Role in Aging and Healthspan with Dr. Sean GibbonsDr. Sean Gibbons joins Dr. Buck Joffrey to discuss the complexities of the gut microbiome, its evolution, and its significant role in health and longevity. He explains how our microbiome is established at birth, how it changes throughout life, and the impact of diet and lifestyle on its composition. The discussion also covers the challenges of modifying the microbiome, the potential of precision nutrition, and the emerging field of fecal transplants. Dr. Gibbons emphasizes the importance of butyrate, a beneficial short-chain fatty acid produced by gut bacteria, and the future of microbiome research...
2025-08-2540 minLongevity Roadmap149: How Dental Health Impacts Longevity with Dr. Ellie PhillipsDr. Ellie Phillips, DDS, joins Dr. Buck Joffrey to explain how oral pathogens contribute to chronic inflammation and conditions such as cardiovascular disease, Alzheimer's, and adverse pregnancy outcomes. She shares the science behind xylitol, saliva-driven remineralization, and practical strategies for supporting a healthy oral microbiome to reduce systemic risk. Learn more about Dr. Ellie Phillips: https://drellie.com/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.lo...
2025-08-1851 minLongevity Roadmap148: Dr. Kevin J. Tracey - Stimulating the Vagus Nerve to Reduce Inflammation and Improve HealthspanDr. Kevin J. Tracey, neurosurgeon, immunologist, and pioneer in bioelectronic medicine, discusses the discovery of the inflammatory reflex and how vagus nerve stimulation can precisely regulate immune activity without immunosuppression. He explains its clinical application in rheumatoid arthritis, potential use in Crohn's disease, multiple sclerosis, and metabolic disorders, and its implications for extending healthspan. Watch the full episode to explore how targeting neural circuits could redefine the treatment of inflammation. Get Dr. Kevin J. Tracey's book, The Great Nerve: https://www.penguinrandomhouse.com/books/746339/the-great-nerve-by-kevin-j-tracey-md/ Learn more about Dr. Tracey: https...
2025-08-1137 minLongevity Roadmap147: The Wrong Vitamin E Supplement Can Hurt You with Dr. Barrie TanIn this conversation, Dr. Barrie Tan joins Dr. Buck Joffrey to discuss the significance of tocotrienols—a lesser-known form of vitamin E—and their potential role in preventing chronic disease and promoting healthy aging. Dr. Tan explains the differences between tocopherols and tocotrienols, the role of vitamin E in human health, and highlights the annatto plant as a key natural source of tocotrienols. The discussion also touches on clinical trials, the anti-inflammatory effects of tocotrienols, and how they work in synergy with other supplements. Learn more about Dr. Barrie Tan: https://barrietan.com...
2025-08-0434 minLongevity Roadmap146: AMA President Dr. Bobby Mukkamala - Healthspan-Centric Medical Care in AmericaJoining Dr. Buck Joffrey this week, Dr. Bobby Mukkamala shares his journey from aspiring cardiothoracic surgeon to becoming the president of the American Medical Association. He discusses his personal health challenges, including a brain tumor diagnosis, and how it has shaped his perspective on healthcare. The conversation delves into the importance of preventative medicine, the impact of the Flint water crisis, and the role of the AMA in shaping the future of healthcare, particularly in the realm of longevity and AI. Dr. Mukkamala emphasizes the need for a shift from reactive to proactive healthcare and addresses the challenges posed...
2025-07-2839 minLongevity Roadmap145: Why Some Animals Live Longer Than Others with Dr. Steven AustadIn this conversation, Dr. Buck Joffrey and Dr. Steven Austad discusse the biology of aging, the evolutionary aspects of longevity, and the potential for genetic technologies to extend human health span. Dr. Austad emphasizes the complexity of aging, the importance of glucose control, and the need for further research into species that exhibit remarkable longevity. The discussion also touches on the challenges and ethical considerations of manipulating human genetics for longevity. Learn more about Dr. Steven Austad: https://www.stevenaustad.com/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy...
2025-07-2135 minLongevity Roadmap144: Why the Brain is Especially Vulnerable to Aging with Dr. Julie AndersenIn this conversation, Dr. Buck Joffrey and Dr. Julie Andersen explore the molecular mechanisms behind neurodegenerative diseases, with a particular focus on the aging brain. They discuss the brain's heightened vulnerability to aging, the impact of mitochondrial dysfunction, and the challenges posed by drug delivery across the blood-brain barrier. The conversation also delves into innovative strategies to support mitochondrial health, including the potential of lysosomal rejuvenators and senolytics, as well as the importance of identifying early biomarkers for neurodegenerative conditions. Dr. Andersen also underscores the critical role of lifestyle interventions—especially exercise—in main...
2025-07-1429 minLongevity Roadmap143: The Longevity Dividend with Prof. Jay OlshanskyIn this conversation, Professor S. Jay Olshansky discusses the evolution of aging science, the realistic limits of human life expectancy, and the concept of the Longevity Dividend, which emphasizes the health and economic benefits of modulating the aging process. He also explores the potential of biomarkers in predicting longevity, the societal implications of an aging population, and the ethical considerations surrounding advancements in longevity science. Learn more about Professor S. Jay Olshansky: http://sjayolshansky.com/sjo/Background.html - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://r...
2025-07-0729 minLongevity Roadmap142: The Gut-Muscle Axis with Dr. Michael Lustgarten In this episode, Dr. Michael Lustgarten discusses his research on the gut microbiome, serum metabolome, and muscle health in older adults. He shares insights from his journey into the world of aging, the importance of data in health optimization, and the emerging concept of the gut-muscle axis. Dr. Lustgarten emphasizes the significance of metabolites in predicting longevity and the need for personalized health tracking. He also addresses the balance of exercise and the role of fecal microbiota transplantation in health. Learn more about Dr. Michael Lustgarten: https://nutrition.tufts.edu/academics/faculty/michael-lustgarten Email Dr. Michael Lustgarten: mlhnrca@gmail.com
2025-06-3029 minLongevity Roadmap141: A Thermostat for Your Body Fat with Dr. Stephan J. GuyenetIn this conversation, Dr. Stephan J. Guyenet joins Dr. Buck Joffrey to discuss the complex mechanisms of body fat regulation, focusing on the role of the lipostat and leptin. He explains how the body regulates fatness through hormonal signals and the implications of leptin resistance in obesity. The discussion also covers practical strategies for weight management, the impact of stress and sleep on leptin levels, and critiques of the carbohydrate insulin model of obesity. Learn more about Dr. Stephan J. Guyenet: https://www.stephanguyenet.com/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: ht...
2025-06-2329 minLongevity Roadmap138: Sleep Impact on Longevity and Health with The Sleep DoctorSleep is the secret weapon for a longer, healthier life—and Dr. Michael Breus is here to show you how to use it. In this episode of Longevity Roadmap, Buck Joffrey dives deep into the science of sleep with the world-renowned sleep doctor himself. Discover why sleep is the third pillar of longevity, how REM sleep and deep sleep fuel physical and emotional restoration, and what your chronotype reveals about your ideal sleep patterns. From the effects of sleep deprivation on metabolism and aging to natural sleep tips, supplements, and cutting-edge alternatives to CPAP machines fo...
2025-06-0257 minLongevity Roadmap137: Dr. Joan Mannick - Targeting mTOR to Improve Immune Function and HealthspanWhat if targeting a single cellular pathway could slow aging and boost immunity? Dr. Joan Mannick, a leading voice in aging science, reveals how mTOR inhibitors may be the future of longevity therapeutics. From her early inspiration to groundbreaking clinical trials, Dr. Mannick explores the role of mTOR in aging, immune response, and antiviral immunity. Learn how selective mTOR inhibition could extend healthspan without compromising muscle mass, improve vaccine response in older adults, and unlock new possibilities in clinical longevity. Learn more about Dr. Joan Mannick: https://www.linkedin.com/in/joan-mannick-8089a614/
2025-05-2642 minLongevity Roadmap136: Why is Vitamin D So Important in Health and Longevity? with Dr. Michael HolickVitamin D is more than a vitamin—it's a hormone that influences everything from your immune system to cardiovascular health, cognition, and longevity. In this conversation, Dr. Michael Holick breaks down the science of vitamin D synthesis, the truth about sun exposure vs. supplements, and why vitamin D deficiency is far more common—and more dangerous—than most people realize. You'll learn how skin pigmentation, UVB exposure, and supplementation protocols impact your vitamin D levels, and why D3 is more effective than D2. Dr. Holick also dives into mood, cognition, and the controversial role of vitamin D in chronic diseas...
2025-05-1942 minLongevity Roadmap135: The Aging Brain - From Memory Lapses to Measurable Prevention with Dr. Mitchell ClionskyIs your memory decline normal—or something more? Clinical neuropsychologist Dr. Mitchell Clionsky breaks down what healthy aging looks like from a cognitive perspective and where concern might be warranted. He introduces the Memory Orientation Screening Test (MOST)—a powerful yet quick tool to assess cognitive health—and shares insights from decades of evaluating memory, dementia, brain injuries, and CTE. From preventive strategies that could reduce dementia risk by nearly 50%, to how technology is transforming neuropsychology, this conversation is a must-watch for anyone invested in long-term brain health. Learn more about Dr. Mitchell Clionsky: https...
2025-05-1231 minLongevity Roadmap134: Can You Boost Stem Cells Naturally? with Dr. Christian DrapeauWhat if your body already had everything it needs to heal itself—naturally? In this episode, neurophysiologist and stem cell researcher Dr. Christian Drapeau breaks down the science of stem cell therapy, explaining how adult stem cells, embryonic stem cells, and exosomes play a central role in regenerative medicine and longevity. Discover how aging affects the body's ability to mobilize stem cells, how injury signals guide them, and why immune system function is tightly linked to stem cell activity. Learn more about Dr. Christian Drapeau and STEMREGEN: https://tinyurl.com/kmvp5972
2025-05-0544 minLongevity Roadmap133: Can We Reverse Immune System Aging? T Cells, Telomeres, and the Fight Against Senescence with Dr. Alessio LannaIs it possible to rejuvenate the immune system as we age? In this episode, Dr. Alessio Lanna breaks down the science of immune aging, focusing on the critical role of T cells, telomere shortening, and senescence. He explains how T cells lose their effectiveness over time—and shares emerging research on how intercellular telomere transfer and the ESMAC complex may help reverse immune senescence. Learn how pharmacological interventions could unlock new possibilities for health, longevity, and immune rejuvenation. Learn more about Dr. Alessio Lanna: https://sentcell.life/team/ - Download Dr. Bu...
2025-04-2833 minLongevity Roadmap131: Matt Kaeberlein - Aging, mTOR, Epigenetic Clocks, and more!What if aging isn't just inevitable—but modifiable? In this episode of Longevity Roadmap, Dr. Matt Kaeberlein breaks down the science of biological aging, with a focus on mTOR, epigenetics, and the hallmarks of aging like cellular senescence, mitochondrial dysfunction, and epigenetic drift. He explores the role of genetics vs. environment, the promise and pitfalls of metformin, NAD boosters, and senolytics, and why interventions like rapamycin and caloric restriction may extend health span. From the limitations of biological age tests to the importance of lean muscle mass, this conversation is a masterclass in evidence-based longevity research.
2025-04-141h 01Longevity Roadmap130: Does the Gut Control the Brain? with Dr. Michael GershonDr. Michael Gershon—legendary Columbia professor and author of The Second Brain—joins us to explain why your intestines might just be running the show. From guinea pig guts that "blew back" to the real reason stress wrecks your digestion, this episode dives deep into the mysterious world of the enteric nervous system. Prepare for gut science, serotonin surprises, and a Woody Allen–esque dose of humor from the father of neurogastroenterology himself. Learn more about Dr. Michael Gershon: https://www.pathology.columbia.edu/profile/michael-d-gershon-md Download Dr. Buck Joffrey's FREE ebook, Living Longer...
2025-04-0735 minLongevity Roadmap125: Reversing Skin Age - Tackling Senescence with OS-01 with Dr. Carolina Reis OliveraVisit oneskin.co/BUCK and use code BUCK at checkout for 15% off your first purchase! Dr. Carolina Reis Olivera shares her journey in aging and longevity research, highlighting the development of the OS-01 peptide—a breakthrough targeting cellular senescence to improve skin health. She delves into the biology of skin aging, the impact of senescent cells, and the cutting-edge strategies OneSkin is using to combat age-related skin conditions. The conversation also explores clinical trials, product efficacy, and the broader systemic benefits of optimizing skin health. Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy Peo...
2025-03-0328 minLongevity Roadmap116: Martin Gibala - The Value of HIIT for Longevity and HealthspanBuck Joffrey interviews Martin Gibala, a professor at McMaster University, about High-Intensity Interval Training (HIIT) and its benefits. They discuss the definition of HIIT, its physiological mechanisms, and how it compares to traditional exercise. The conversation also covers the implications of HIIT for different populations, its connection to VO2 max and longevity, practical applications in daily life, safety considerations, and resources for further learning. 00:00 - Introduction to High-Intensity Interval Training (HIIT) 04:39 - Physiological Mechanisms of HIIT vs. Traditional Exercise 08:34 - HIIT for Different Populations and Health Benefits 12:30 - VO2 Max and Longevity: The HIIT C...
2024-12-3029 minLongevity Roadmap114: Traditional Lab Studies Can Miss Deadly DiseaseIn this episode, Buck Joffrey discusses the importance of going beyond the normal scope of testing when it comes to lipid profiles and cardiovascular health management. He emphasizes the significance of understanding cholesterol particles, particularly APO-B, and lipoprotein(a), in assessing heart disease risk. He also highlights preventative strategies to optimize health and mitigate risks associated with cardiovascular disease.
2024-12-1620 minLongevity Roadmap113: Lipid Management with Coronary Artery Disease and e2/e4 GenotypeIn this episode of Longevity Roadmap, Buck Joffrey presents a case study of a 70-year-old patient with optimal metabolic health but elevated LDL and APOB levels, emphasizing the importance of aggressive lipid management in preventing coronary artery disease. Buck also explores the genetic factors related to Alzheimer's risk and the implications of lipid levels on cognitive health, advocating for proactive treatment strategies. 00:00 - Introduction to Longevity Roadmap 03:08 - Case Study: A 70-Year-Old Patient's Health 12:07 - Understanding Lipid Management and Atherosclerosis 19:49 - Genetic Factors in Alzheimer's Risk and Lipid Management
2024-12-0918 minWealth Formula by Buck Joffrey481: Finance and Market News 11/27/24Buck Joffrey and Zulfi Ali tackle critical issues shaping the U.S. economic landscape, from the mounting government debt and entitlement challenges to the looming risks of a debt crisis. They examine the current state of U.S. debt, its global context, and the future of treasury auctions, emphasizing the unsustainable debt-to-GDP trajectory and the political hurdles in reforming entitlements.
The conversation also delves into the economic ripple effects of the Trump administration’s policies on inflation, growth, and the stock market, alongside the shifting dynamics of treasury yields. Buck and Zulfi explore the evolving cryptocurrency market, fo...
2024-11-2742 min
Wealth Formula Podcast481: Finance and Market News 11/27/24Buck Joffrey and Zulfi Ali tackle critical issues shaping the U.S. economic landscape, from the mounting government debt and entitlement challenges to the looming risks of a debt crisis. They examine the current state of U.S. debt, its global context, and the future of treasury auctions, emphasizing the unsustainable debt-to-GDP trajectory and the political hurdles in reforming entitlements. The conversation also delves into the economic ripple effects of the Trump administration's policies on inflation, growth, and the stock market, alongside the shifting dynamics of treasury yields. Buck and Zulfi explore the evolving cryptocurrency market, focusing on Solana and...
2024-11-2742 minWealth Formula by Buck JoffreyHas the first person to live to 500 already been born?Buck introduces his brand new health and longevity podcast, Longevity Junky.
Longevity Junky is a compelling and accessible new podcast that works for all longevity enthusiasts, whether you’re a hardened scholar who craves detailed science or a relative newcomer to this fascinating and quickly evolving world.
Dr. Buck Joffrey, MD, is a former neurosurgeon, successful entrepreneur, and self-described health-conscious hedonist.
Nikki Leigh is a jet-setting actress influencer with 6M followers and is the OG Longevity Junky.
They’re good friends and willing guinea pigs for all longevity-related experiments.
From...
2024-09-1356 minWealth Formula PodcastHas the first person to live to 500 already been born?Buck introduces his brand new health and longevity podcast, Longevity Junky. Longevity Junky is a compelling and accessible new podcast that works for all longevity enthusiasts, whether you're a hardened scholar who craves detailed science or a relative newcomer to this fascinating and quickly evolving world. Dr. Buck Joffrey, MD, is a former neurosurgeon, successful entrepreneur, and self-described health-conscious hedonist. Nikki Leigh is a jet-setting actress influencer with 6M followers and is the OG Longevity Junky. They're good friends and willing guinea pigs for all longevity-related experiments. From hallucinogens to full body MRIs, micro-dosing Cialis to tech, exercise, and diet...
2024-09-1356 minLongevity Roadmap89: The Nine Pillars of Resilience with Stephen Sideroff, PhDBuck Joffrey, MD discusses the concept of resilience with Stephen Sideroff, PhD. Topics include bouncing forward from stress and practical techniques to restore balance, nurture growth, and slow down the aging process. 01:35 Defining Resilience and the Ability to Adapt 08:21 Physical Balance and Mastery: Restoring Balance in the Nervous System 15:26 Self-Relationship: How It Changes Your Physiology 21:47 Resilience and Longevity 23:16 Emotion Balance and Mastery
2024-06-2428 minLongevity Roadmap86: The Science of Human AttractionBuck Joffrey, MD reviews the literature on the topic of human attraction. Topics include the brain, perception of beauty, specific aspects of beauty, and sexual dimorphism. Also included is a discussion on the role of human pheromones and attraction. Show Notes: 01:20 Facial Attraction & Cues 08:30 Facial Symmetry 11:12 The Averageness of Facial Features 13:59 Clear and Unblemished Skin 15:44 Sexual Dimorphic Traits 22:23 Smell and Pheromone
2024-06-0329 minWealth Formula by Buck Joffrey431: Wealth Formula Banking Webinar ReplayBuck Joffrey is joined by Rod Zabriskie and colleagues of Wealth Formula Banking to discuss this powerful financial tool that leverages your savings to invest the same money at two places at the same time.
2024-05-2400 minWealth Formula Podcast431: Wealth Formula Banking Webinar ReplayBuck Joffrey is joined by Rod Zabriskie and colleagues of Wealth Formula Banking to discuss this powerful financial tool that leverages your savings to invest the same money at two places at the same time.
2024-05-2431 minLongevity Roadmap84: Keto Diet 101Buck Joffrey, MD discusses the basics of the keto diet with Amy Berger, a certified nutrition specialist. Topics include the definition of the diet, its health benefits and its role in the treatment of various disease processes including type 2 diabetes and Alzheimer's Disease. Show Notes: 03:08 Why the Keto Diet? 04:15 How Does the Keto Diet Help You Lose Weight? 05:51 Other Benefits of the Keto Diet 09:14 How Does High Blood Sugar Result in Insulin Resistance? 11:44 What Defines a Keto Diet 16:13 Lifestyle VS Intervention 19:02 The Concern...
2024-05-2034 minLongevity Roadmap83: Sexually Transmitted CancerBuck Joffrey, MD reviews what is known about sexually transmitted cancers. Discussion includes HIV and Hepatitis but focuses on Human Papilloma Virus which Buck believes is grossly underappreciated by people and by physicians. 01:18 HIV 05:26 Hepatitis 09:20 HPV
2024-05-1322 minLongevity Roadmap82: Intro to the MicrobiomeBuck Joffrey, MD provides an introduction to the microbiome and discusses its importance. Topics also include prebiotics, probiotics, and postbiotics.
2024-05-0624 minLongevity Roadmap81: Ask the Doctor 04/29/24Buck Joffrey, MD, takes questions from the audience. Topics include human growth hormones, the potentially harmful effects of an MN, 40 Hz therapy, and visceral fat. Show Notes: 00:47 Is It Fine That I Sleep Too Much? 08:08 The 40hz Gamma Frequency and How It Relates to Brain Health 13:28 The Anti-Aging Effects of Human Growth Hormone 20:31 Reconsideration of How to Fast 29:22 Potentially Harmful Effect of NMN 33:08 Visceral vs Subcutaneous Fat
2024-04-2937 minLongevity Roadmap80: The Longevity Diet with Valter Longo, PhDBuck Joffrey, MD, discusses the fasting regimen with Dr. Valter Longo, PhD. Dr. Longo is a world, renowned researcher in longevity and the author of: The Longevity Diet. Show Notes: 01:10 Types of Fasting 03:31 Why Fasting is Beneficial From a Cellular Level 07:00 Intermittent Fasting VS Fast Mimicking Diet 14:05 How Does Fasting Help Cancer Patients 20:37 What Is in the Fast Mimicking Diet 33:38 Pills and Supplements for Fasting Mimicking Diet 41:23 Time-Restricted Feeding Based on Circadian Rhythm
2024-04-2254 minWealth Formula by Buck Joffrey423: Campbell Harvey Says the Fed is WRONG on Inflation and Interest RatesEven really smart people are wrong on a regular basis. I see this all the time in health and longevity-related issues on my other podcast, Sapio with Buck Joffrey.
In case you are wondering…yes, I have become one of those middle-aged California guys trying to stay young at all costs. Not easy. But, I have to admit, the nerdy physician scientist type in me is having lots of fun with the science and enjoying the process of sharing it with my fellow Gen-Xers who are also fighting gravity with me.
But getting back to th...
2024-04-2139 minWealth Formula Podcast423: Campbell Harvey Says the Fed is WRONG on Inflation and Interest RatesEven really smart people are wrong on a regular basis. I see this all the time in health and longevity-related issues on my other podcast, Sapio with Buck Joffrey. In case you are wondering…yes, I have become one of those middle-aged California guys trying to stay young at all costs. Not easy. But, I have to admit, the nerdy physician scientist type in me is having lots of fun with the science and enjoying the process of sharing it with my fellow Gen-Xers who are also fighting gravity with me. But getting back to the point of smart people be...
2024-04-2139 minLongevity Roadmap79: Lies Taught in Medical School: Robert Lufkin, M.D.Buck Joffrey, MD interviews Robert Lufkin, MD about his book Lies I Taught in Medical School: And the Truths That Can Save Your Life Topics include metabolic syndrome, intermittent fasting, and various outdated information still used in mainstream medicine that may have deleterious effects on people's health. Show Notes: 01:35 Dr. Lufkin's Personal Journey to Question the Medicine Establishment 04:14 When Did People Start to Take Metabolic Syndrome Seriously? 08:33 What Exactly is Metabolic Syndrome from a Physiological Standpoint? 10:21 The Balance Between Building and Breaking Down in the Metabolic System
2024-04-1538 minLongevity Roadmap78: The Age of Data-Driven Wellness is HereDr. Buck Joffrey, M.D. interviews, Dr. Nathan Price, PhD from Thorne about a new paradigm in medicine driven by data, technology, and self-empowerment. Show Notes: 00:58 What Really is Healthspan? 05:06 Biological Age VS Chronological Age 07:41 The Factors that Determine Biological Aging 12:08 What Happens When You Artificially Suppress These Factors 16:58 What is Phenomics and how can it predict diseases? 24:21 How Can You Do Self Tests?
2024-04-0831 minLongevity Roadmap76: Intermittent Fasting Correlated to Higher Risk of Cardiovascular DeathIn this episode of Sapio, Dr. Buck Joffrey, MD addresses the recent American Heart Association study correlating intermittent fasting/time restricted, feeding to higher rates of cardiovascular death. Buck breaks down what we already know about the data behind intermittent fasting in both animals and in humans and tries to put the most recent study into context. He provides feedback on the study itself, including some suggestions on how to use this new information. Show Notes: 02:01 Intermittent fasting vs caloric restriction 06:57 Why Intermittent Fasting Improves Metabolic Health 10:19 Intermittent fasting while maintaining...
2024-03-2527 minLongevity Roadmap75: Stress, Cortisol and Prevention StrategiesBuck Joffrey, MD talks to Romie Mushtaq, MD regarding stress, cortisol levels and prevention strategies including meditation and anti-inflammatory diets. Show Notes: 02:14 The definition of stress 13:16 Why does stress disrupt circadian rhythms and sleep 16:08 How do we treat stress? 21:23 Nootropics 24:39 Vagal nerve stimulator 28:34 Digital detox and meditation 33:02 Diet for stress
2024-03-1846 minLongevity Roadmap74: Aggressive Male TRT Approach, Erectile Dysfunction Drugs, and Alzheimer's DiseaseBuck Joffrey MD speaks to Justin Houman MD who is a urologist regarding the idea of aggressive testosterone treatment to decrease the risk of metabolic syndrome and therefore multiple other disease processes that are downstream. Other topics disgust include erectile dysfunction, early treatment with ED meds and the correlation with Alzheimer's disease. Show Notes: 1:27 Is it true that the testosterone in men in general has gone down? 02:43 Common symptoms of low testosterone 05:15 Normal level of testosterone 07:19 Testosterone and metabolic syndrome 12:49 Testosterone replacement therapy and cancer 16:03...
2024-03-1145 minLongevity Roadmap73: Is a Vegan Diet Healthy?Buck Joffrey, MD and Linda Tyler, PhD discuss the topic of plant-based only/Vegan diets. The conversation includes topics on inflammation and nutritional concerns. Show Notes: 2:55 A plant-based diet for better health? 11:53 Balancing nutritions for the plant-based diet 20:39 Accessibility of the plant-based diet 22:30 Processed plant-based food
2024-03-0434 minLongevity Roadmap72: A Different Framework for Health?Buck Joffrey, MD interviews Anoop Kumar, MD on his perspective on health and wellness. Dr. Kumar is an emergency medicine doctor who is also knowledgeable about traditional Indian Philosophy and medicine. Show Notes: 00:43 Near-Death Experience and Shift in Perspective 07:04 The Three Minds Framework 23:03 Reevaluating the Model of Human Anatomy 27:20 The Four Engines: Nutrition, Movement, Connection, and Rest 39:24 The Four Engines of Health and Healing 41:01 Harnessing the Placebo Effect and Self-Healing
2024-02-2649 minLongevity Roadmap70: The Science Behind Music and Mental HealthBuck Joffrey, MD interviews Dr. Daniel Bowling from Stanford University on the science behind music and mental health. Bowling discusses the fundamentals of musicality and the research that has been done in this relatively new field of music as treatment for health-related issues. Show Notes: 02:59 What is musicality? 04:47 What is tonality? 07:05 How does music affect the brain? 11:20 Music as treatment for mental health 22:22 Does music sharpen our intellect? 27:05 Musical vs pharmaceutical interventions 30:38 How to get started on music therapy
2024-02-1237 minWealth Formula by Buck Joffrey413: Social Security Scams and “Retirement” PlanningRetirement means “ceasing to work”. In my case, retirement will describe me when I’ve died.
I understand retiring from a particular activity. Like how I retired from the practice of surgery about eight years ago. But global retirement sounds dire.
It is like admitting that you are of no real value to the world anymore. That your contributions are no longer of benefit to humanity.
I’ve always believed that the universe ultimately pays you what you deserve. If all you’re doing is playing golf, you aren’t worth a dime.
And im...
2024-02-1140 minWealth Formula Podcast413: Social Security Scams and "Retirement" PlanningRetirement means "ceasing to work". In my case, retirement will describe me when I've died. I understand retiring from a particular activity. Like how I retired from the practice of surgery about eight years ago. But global retirement sounds dire. It is like admitting that you are of no real value to the world anymore. That your contributions are no longer of benefit to humanity. I've always believed that the universe ultimately pays you what you deserve. If all you're doing is playing golf, you aren't worth a dime. And imagine all of that knowledge, expertise and wisdom you accumulate...
2024-02-1137 minLongevity Roadmap69: Glutathione: The Master AntioxidantBuck Joffrey, MD welcomes pharmacist and glutathione expert Dr. Nayan Patel. This podcast discusses the role of glutathione as an antioxidant including why it is known as the "master" antioxidant. The discussion reviews the physiology of glutathione in the body focussing on disease prevention and also discusses different mechanisms of supplementation. Show Notes: 00:48 What is oxidative stress? 04:12 What is an antioxidant and how does it work? 10:24 Glutathione and its relationship to longevity 29:12 Dr. Patel's Auro Wellness
2024-02-0548 minLongevity Roadmap67: The Silent Global Epidemic KillerBuck Joffrey, M.D. discusses metabolic syndrome which affects 1/4 of the global adult population and how it underlies the development of virtually every other major cause of death. Show Notes: 00:13 Understanding Metabolic Syndrome 05:29 Criterias of Metabolic Syndrome 23:40: Insulin Resistance and Hyperinsulinemia 24:49: Metabolic Syndrome and Diabetes 37:49: Recommended Lab Tests 42:05: The Health Implications of Liposuction 50:42: The Importance of HSCRP
2024-01-2246 minLongevity Roadmap60: InflammagingBuck Joffrey, MD summarizes his literature search on what the data says in regards to the mechanisms by which the most common diseases of age such as cardiovascular disease and cancer might be correlated with chronic inflammation. There is also a discussion around the role of therapeutics and supplements as it relates to treating chronic inflammation and aging related disease.
2023-12-1839 minLongevity Roadmap59: How Much Exercise Is Too Much For Longevity?In this brief video, Buck Joffrey discusses literature suggesting that there is a "Goldilocks" zone for exercising for longevity. He also talks about the research on ultramarathoners suggesting that the once an upper limit of exercise is exceeded, risks to health potentially outweigh the benefits.
2023-12-1305 minLongevity Roadmap56. Ask the Doctor (December 2023)In this episode of Sapio with Buck Joffrey, Buck welcomes back Dr. Alan Viglione of Montecito Concierge Medicine. Dr. Viglone discuss several topics based on audience questions including: 00:03:01:15 Is moderate alcohol intake good or bad for you? 00:09:08:02 Pills for alcohol cravings 00:15:40:20 Is the carnivore diet healthy? 00:22:20:22 Optimal exercise for endurance runners 00:30:43:04 Where and why you should get genetic testing done to prevent disease? 00:36:46:13 Can you do anything about your gene that makes you prone to Alzheimer's diease? 00:40:24:09 Is human growth hormone or sermorelin bad for yo...
2023-12-0456 minLongevity Roadmap55: Engaging Your Subconscious For SuccessIn this episode of Sapio with Buck Joffrey, Buck discusses the importance of setting clear goals and truly believing they can be achieved. He emphasizes the need to honestly evaluate if one's current plans will achieve their goals, and make adjustments if needed.
2023-11-2911 minLongevity Roadmap54: What Supplements Does Buck Take?In this episode of Sapio with Buck Joffrey, Buck reveals the supplements and drugs that he takes for the purpose of longevity. In addition to providing specific drugs and supplements, he talks about the reasoning for each and the big picture around how he looks at longevity regimens. Show Notes: 00:03:38:01 A legit source of information for supplements 00:04:17:24 Supplements for cardiovascular diseases 00:10:10:19 Supplements for all organs 00:14:21:07 Supplements for longevity
2023-11-2722 minLongevity Roadmap51: Part 2: Alzheimers's Disease: Risk Factors, Prevention and TreatmentIn our last episode of Sapio with Buck Joffrey, Neurologist Dr. John Foley took us through the diagnosis and pathophysiology behind Alzheimer's disease He also told us about the risk factors for getting Alzheimer's disease—both avoidable and not. In this episode, we talk about what we can do to mitigate the risk of developing Alzheimer's disease, even if you are genetically predisposed to it. We talk about everything from Saunas to supplements. We also take a look at the cutting-edge research and new therapies that might actually be able to treat Alzheimer's disease that may...
2023-11-1545 minLongevity Roadmap50: Part 1: Alzheimers's Disease: Risk Factors, Prevention and TreatmentIn the next two episodes of Sapio with Buck Joffrey, we are going to talk about Alzheimer's disease. If you have never seen someone progress through the different stages of Alzheimer's disease, consider yourself lucky. This is a heartless disease that robs people of their most prized possession: their memories of their loved ones and of everything else about their lives. It also robs them of their ability to function in this world. Over the next 2 episodes of Sapio, you are going to learn what Alzheimer's disease is, what the risk factors are...
2023-11-1341 minLongevity Roadmap47: Exercising for Longevity and More with Dr. Tom Walters | 2 of 2Sapio with Buck Joffrey Episode 47 is part 2 of a 2 part episode with Dr. Tom Walters, DPT, OCS. Tom is a Doctor of Physical Therapy, former Kinesiology Professor, author of the bestselling book "Rehab Science: How to Overcome Pain and Heal From Injury". He is also an Instagram and YouTube creator with with more than 1.6 million combined followers, with a focus on "Alleviating Pain and Moving Better". In part 2 of this 2 part episode Tom and Buck discuss supplements, sleep, pain and the things you should be doing to help you live longer and stay healthier. Make...
2023-11-0132 minLongevity Roadmap46: Exercising for Longevity and More with Dr. Tom Walters | 1 of 2Sapio with Buck Joffrey Episode 46 is part 1 of a 2 part episode with Dr. Tom Walters, DPT, OCS. Tom is a Doctor of Physical Therapy, former Kinesiology Professor, author of the bestselling book "Rehab Science: How to Overcome Pain and Heal From Injury". He is also an Instagram and YouTube creator with with more than 1.6 million combined followers, with a focus on "Alleviating Pain and Moving Better". In part 1 of this 2 part episode Tom and Buck discuss excercise and the things you should be doing to help you live longer and stay healthier. Also discussed in detail is...
2023-10-3043 minLongevity Roadmap44: This Old Gout Drug May Help You Live LongerIn Episode 44 of Sapio with Buck Joffrey, Buck discusses research that shows this old drug can be repurposed to fight the number one killer.
2023-10-2305 min
Longevity Roadmap40: Full Body MRI: Avoiding Health Time BombsIn this Sapio with Buck Joffrey episode Buck talks to Dr. Sean London from Prenuvo. A company revolutionizing healthcare with it's full body MRI scans. This is all about Medicine 3.0. Early detection is key in fighting many diseases including cancer for example. Buck recently had the procedure and Dr. London goes through some of the findings - one of which was a bit of a surprise.
2023-10-0945 min
Longevity Roadmap39: Tipping the Scales: A Closer Look at Wegovy & Ozempic for Weight Loss🎧 Dive deep into the world of weight loss solutions in this eye-opening episode of Sapio with Buck Joffrey. As the buzz around Wegovy and Ozempic intensifies, we dissect the promises and pitfalls. Can it truly tip the scales in favor of those battling the bulge? Join us for an exploration of this groundbreaking treatment. 👍 Like, share, and weigh in: Would you consider Wegovy as a weight loss solution? #SapioPodcast #BuckJoffreyInsights #WegovyExplained #TippingTheScales #WeightLossInnovation #BeyondTheBuzz #HealthTrends #ModernMedicine #WeightLossJourney #DiabetesToDiet #Wegovy #Ozempic #semaglutide
2023-10-0406 min
Longevity Roadmap38: What is your TRUE age? Biological VS ChronologicalIn this Sapio with Buck Joffrey Episode Short, Buck discusses Biological Age and how it is different than Chronological Age. Which of the two should be the true measure of a person's age?
2023-10-0204 min
Longevity Roadmap37: Psilocybin: Evidence that a Psychedelic May Treat DepressionIn this Sapio with Buck Joffrey Medical Update, Buck discusses depression and the psychedelics being used to treat it including Psilocybin and Ketamine. Depression can have a series negative impact on longevity and impacts millions of people.
2023-09-2705 min
Longevity Roadmap36: Cold Therapy: Real Science or Cool Trend?🎧 New Episode of Sapio with Buck Joffrey: The world is buzzing about the benefits of cold therapy, but is it all it's cracked up to be? 🧊 Buck delves deep into the icy waters of this wellness trend, separating fact from fiction and exploring whether the chills are worth the hype. Tune in for an eye-opening discussion and decide for yourself! 👍 Like, share, and let us know your thoughts on cold therapy! #SapioPodcast #BuckJoffreyInsights #ColdTherapyTruths #WellnessDebunked #HealthySkepticism #WellnessTrends #FactOrFiction #HealthMyths
2023-09-2516 min
Longevity Roadmap35: Is Hearing Loss Connected to Dementia?In this Sapio with Buck Joffrey Medical Update, Buck discusses new reasearch that connects hearing loss and dementia. If you or a loved one is suffering from hearing loss you are going to want to take action.
2023-09-2004 min
Longevity Roadmap34: Female Sexual DysfunctionIn this episode of Sapio with Buck Joffrey Dr. Duncan Turner joins Buck for a conversation on women's health, sexual dysfunction and what can be done about it.
2023-09-1835 min
Longevity Roadmap31: What Covid does to your BrainEpisode 31 of Sapio with Buck Joffrey discusses "What Covid does to your Brain". In this short episode Buck discusses his personal experience and the after affects which lasted several weeks after testing negative. 00:00:12 - Buck's experience with the original COVID strain 00:01:12 - COVID and Depression 00:01:57 - Damage to the Ventral Striatum and Anhedonia 00:02:19 - COVID possibly affecting the Posterior Putamen which is involved with speech, articulation and other cognitive functioning
2023-09-0603 min
Longevity Roadmap30: What's Your Risk of Getting Alzheimer's Disease?In this episode of Sapio with Buck Joffrey, Buck discusses a new study out of Oxford that outlines 11 key risk factors for dementia. And the good news - while you can't change everything, many of these factors can be controlled buy modifying behaviors. If your want to see more info on the study goto: https://www.psych.ox.ac.uk/news/new-dementia-risk-score-helps-identify-people-at-risk. 00:00:02 - The difference between Alzheimer's Disease and Dementia 00:01:02 - Diagnosing Alzheimer's disease 00:01:25 - Causes of Dementia 00:01:48 - Dementia risk factors and how to avoid them 00:03:08 - Parental Dementia 00:03:27 - APOE e4 as a risk...
2023-09-0408 min
Longevity Roadmap25: Heart Rate Variability (HRV)Buck discusses Heart Rate Variability (HRV). What is it? Why does it matter and how can it effect your overall health in this mini Sapio with Buck Joffrey episode. 00:00:31 - Medicine 3.0: Taking medicine into your own hands 00:01:15 - What is Heart Rate Variability (HRV) anyway? 00:02:16 - The Autonomic Nervous System 00:02:37 - The Parasympathetic Nervous System 00:03:32 - Lower Hrv Has Been Linked To An Increased Risk Of Cardiovascular Diseases 00:04:18 - Ways To Increase Your HRV
2023-08-1605 min
Longevity Roadmap3: Why Hyperglycemia is a KILLER (and what to do about it)In this bonus Q&A episode Buck Joffrey dives a little deaper into one of the key Episode 2 topics - blood glucose and how it affects your body with Sapio Executive Producer Ben Hyatt. Shownotes: 0:01:36 Understanding Glucose and Insulin Interaction 0:06:19 Food Combinations and Blood Sugar 0:10:56 Understanding Diabetes and Glycation 0:16:13 Diabetes and Testing
2023-05-2627 minWealth Formula by Buck Joffrey226: Ask Buck Part 2
We do a lot of interview based content on Wealth Formula Podcast. However, the feedback I get is that the most learning happens during our “Ask Buck” episodes.
The good news is that we have a bunch of questions lined up so we will do a couple of “Ask Buck” shows in a row for the next few weeks. We had our first round of questions last week and have more great questions being answered for this week’s episode!
I also encourage you to go back and listen to older “Ask Buck” shows as well. It’s probabl...
2020-08-2340 min
Wealth Formula Podcast148: Dentacoin? What?Welcome back to the show everyone. I hope you enjoyed the show. If I were a dentist, I would definitely check this out. Think of it this way. The concierge aspect of the model is valuable in and of itself. If you don't care for cryptocurrency, immediately convert your crypto to dollars. If you want, keep some in crypto and see it potentially 100X in the next few years. Anyway, I like the idea and it may be worth checking out. Let's talk about some things happening in the crypto space right now. Nasdaq launched real-time information on two new...
2019-03-0350 min
Consensus Network: Cryptocurrency News & EducationEP30: Dentacoin? What?Let's talk about some things happening in the crypto space right now. Nasdaq launched real-time information on two new indices linked to the crypto asset market —Bitcoin liquid index (BLX) and Ethereum Liquid Index (ELX) were both incorporated into the Nasdaq platform on February 25th. This is sort of like the Nasdaq composite with the end goal to bolster mainstream adoption by fusing crypto assets into traditional entities like the stock market. Bitcoin surpassed PayPal in yearly transaction volumes in 2018 with $1.3 trillion dollars more then doubling PayPal with just over $500 billion The CBOE/Van Eck ETF ETF...
2019-03-0350 min
Consensus Network: Cryptocurrency News & EducationEp2: Weekly Crypto News - 09/27/2018The host of Consensus Network, Buck Joffrey, brings you the latest news in the crypto world as of 09/27/2018.
2018-09-2720 min
Consensus Network: Cryptocurrency News & EducationEp1: Bitcoin, Blockchain, Distributed Ledgers, and CryptocurrencyEpisode one of Consensus Network covers the basics of bitcoin, blockchain, and distributed ledgers by Buck Joffrey MD. This is an introduction to the topics and is intended for those with limited knowledge of the topics. In addition to discussing the technical basics in a very conceptual manner, Buck Joffrey dives into the significance of the technology not only from the stand point of technology but as a world movement. The episode concludes with a question and answer session. Ready for more? Go to www.consensusnetwork.io.
2018-09-2039 min
Wealth Formula PodcastUntold Secrets of the Successful: Jorge Newberry"Sexual transmutation is the most powerful tool in existence when it come to creation, invention, accomplishment, creativity, advancement, and achievement." - Napolean Hill, Think and Grow Rich This is a quote from one of my favorite books. It's in the chapter than no one talks about on sexual transmutation. If you have read the book, you know why. It's kind of a weird chapter in the middle of the most mimicked book in Self-Help history. In a nutshell, Napolean Hill says that harnessing sexual energy is the most powerful and efficient means of accomplishing our platonic goals. It took me...
2018-02-2545 min
Wealth Formula Podcast049: Leverage is time with Ari MeiselWhat is leverage? The action of a lever by definition is to gain some kind of advantage. It can be physical like when you are using a tool or, in finance terms, it is the use of borrowed money to enhance buying capacity (and hopefully increase return on investment). A few shows ago I emphasized that my belief was that coveted currency for most, whether realized or not, is time. I equate wealth with time rather than dollars in the bank. Therefore, time is my currency of choice. On this show, we often emphasize the idea of residual cash flow...
2017-04-0923 minWealth Formula by Buck Joffrey049: Leverage is time with Ari MeiselWhat is leverage? The action of a lever by definition is to gain some kind of advantage. It can be physical like when you are using a tool or, in finance terms, it is the use of borrowed money to enhance buying capacity (and hopefully increase return on investment).
A few shows ago I emphasized that my belief was that coveted currency for most, whether realized or not, is time. I equate wealth with time rather than dollars in the bank. Therefore, time is my currency of choice. On this show, we often emphasize the idea of...
2017-04-0923 minWealth Formula Podcast007: Kiyosaki's Quadrant from a Professional's PerspectiveBuck Joffrey's Wealth Formula Podcast Episode 7 Release date: Fri, 24 Jun 2016
2017-04-0621 minWealth Formula Podcast047: Making Yourself Rich and Giving to the Poor with Old Dawg ManasseroEveryone defines wealth a little differently. My own definition of wealth is in the form of an equation wealth=time. Time is my currency of choice. It gives me the freedom to do whatever I like with my life. For the last 2 days, I took my three little girls (8,4,2) sledding in in the afternoon while most of my friends were at work. We had a lousy winter in Chicago--cold but not very snowy. We had to get some sledding in while we could after getting a big snow fall! Don't get me wrong. As a general rule, I am not...
2017-03-2634 minWealth Formula by Buck Joffrey047: Making Yourself Rich and Giving to the Poor with Old Dawg ManasseroEveryone defines wealth a little differently. My own definition of wealth is in the form of an equation wealth=time. Time is my currency of choice. It gives me the freedom to do whatever I like with my life. For the last 2 days, I took my three little girls (8,4,2) sledding in in the afternoon while most of my friends were at work. We had a lousy winter in Chicago–cold but not very snowy. We had to get some sledding in while we could after getting a big snow fall!
Don’t get me wrong. As a gene...
2017-03-2634 minWealth Formula by Buck Joffrey039: Chocolate Covered Profits with David Sewell!I had a really interesting week. As you know I launched my book 7 Secrets of Eternal Wealth a week or so ago and it became an international best seller. I also got invited to appear on 7-8 TV show to talk about the book. So I’m excited to get our message out to more people. Thank you to all those that bought it and wrote a review. By the way, if you like what I’m doing please do share it with others. I send out notifications via social media. You can friend me…look for Buck Joffrey. You ca...
2017-02-0535 min