Shows
Skeleton CrewHow AI is Transforming Radiology, with Cecile Hourquet of GleamerOn this episode of the "Skeleton Crew Show," join our host Jenn and her special guest, Cecile Hourquet, a Marketing & Communication Manager in the AI tech industry, as they delve into the impact AI has on the field of Radiology, and offer eye opening insight on the development of AI in healthcare!2023-07-2830 min
Ask Stago (english version)S3E12 - Fibrinolysis: the often missed key player of hemostasisWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Professor Romaric Lacroix will explain us how fibrinolysis is important to the whole hemostasis process and how the sample fibrinolytic activity needs to be evaluated and sometimes monitored.
Link to previous podcasts:
S1E15 – Disseminated Intravascular Coagulation (DIC) and fibrin related markershttps://www.podcastics.com/podcast/episode/15-disseminated-intravascular-coagulation-dic-and-fibrin-related-markers-54016/
Literature sources:
Cointe S, Vallier L, Esnault P, Dacos M, Bonifay A, Macagno N, Harti Souab K, Chareyre C, Ju...2022-12-0609 min
Ask Stago (english version)S3E11 - What is Factor parallelism for?Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation. In today’s episode, our guest Tom Childs will help us to understand the goal and clinical benefits of the Factor parallelism method.
Link to previous podcasts:
S1E11 – How to be more productive (part 1): implementation of a rules enginehttps://www.podcastics.com/podcast/episode/10-how-to-be-more-productive-part-1-implementation-of-a-rules-engine-37749/
S2E8 - World Hemophilia Dayhttps://www.podcastics.com/podcast/episode/s2e8-world-hemophilia-day-72341/
S2E4 - How to determine factor levels in hemophilia?https://www.pod...2022-11-0811 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E10 - Le dosage des AOD : comment, quand et pourquoi ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, notre invité expert est Jonathan Douxfils, président de QUALIBlood SA et professeur à l’université de Namur au département de pharmacie. Il détaillera les recommandations actuelles sur la mesure des anticoagulants directs oraux et les indications cliniques dans lesquelles ce dosage s’avère pertinent et utile.
Pour en savoir plus :
Bernier M, Lancrerot SL, Parassol N, Lavrut T, Viotti J, Rocher F, Drici MD. Therapeutic Drug Monitoring of Direct Oral Anticoagulants May Increase Their Benef...2022-10-2014 min
Ask Stago (english version)S3E10 - Pediatric hemostasis: are children “small adults”?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Gabrielle Pearl will explain us the particularities of thrombosis and hemostasis in pediatric population, and how to manage pediatric patient samples in the clinical laboratory.
Link to previous podcasts:
S2E5 - How to collect and prepare the coagulation samples properly?
https://www.podcastics.com/podcast/episode/s2e5-how-to-collect-and-prepare-the-coagulation-samples-properly-67393/
S2E3 - How to establish and control the reference range of my assay?
https://www.podcastics.com/po...2022-10-0409 min
Ask Stago (english version)S3E9 - The importance of Fibrinogen.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert Lydie Nicoud, R&D reagent manager, will talk with us about the test of fibrinogen.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Literature sources:
Miesbach W, Schenk J, Alesci S, Lindhoff-Last E, Comparison of the fibrinogen Clauss assay and the fibrinogen PT derived method in patients with dysfibrinogenemia .Thromb Res. 2010; 126(6): e428-33
Karapetian H...2022-09-0611 min
Ask Stago (english version)S3E8 - Venoms and coagulation: when evolution reveals useful for drug and assay development.Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Dr Bryan G Fry, aka Venom Doc, will make us enter his world and understand how venom interact with coagulation and how they can prove useful for assay or drug design & development
Literature sources:
Fry BG, Roelants K, Champagne DE, Scheib H, Tyndall JD, King GF, Nevalainen TJ, Norman JA, Lewis RJ, Norton RS, Renjifo C, de la Vega RC. The toxinogenomic multiverse: convergent recruitment of pr...2022-08-0211 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E7 - Le boom digital des laboratoires d’analyses médicalesBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, c’est Cécile Hourquet, Responsable de gamme eSolutions et services, et habituellement animatrice qui prendra la place d’invité pour parler de la transformation profonde du quotidien des laboratoires d’analyses médicales grâce à la digitalisation.
Pour en savoir plus :
Podcast associé : Episode Ask Stago 🇫🇷 S1E3 - La cybersécurité pour les laboratoires médicaux
🎧 Apple Podcasts : https://lnkd.in/dTpjjXz
Google Podcasts: https://lnkd.in/d7NfJ5X
Spotify : https://lnkd.in/dq_FYXr ...2022-07-2810 min
Ask Stago (english version)S3E7 - Hemostasis results interpretation along pregnancy.Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest François Depasse will help us to understand the hemostasis results obtained along pregnancy, what are the related difficulties for the lab and
Link to previous podcasts:
S1E15 Disseminated Intravascular Coagulation (DIC) and fibrin related markers:https://www.podcastics.com/podcast/episode/15-disseminated-intravascular-coagulation-dic-and-fibrin-related-markers-54016/
S2E1 Whole Blood Viscoelastic Testing (VET)https://www.podcastics.com/podcast/episode/s2e1-whole-blood-viscoelastic-testing-vet-55204
Literature sources:
Szecsi PB, Jørgen...2022-07-0516 min
Ask Stago (english version)S3E6 - IVDR: what is at stake for IVD manufacturers and for the laboratories?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Sophie Réhault will give us explanations on what is the new EU IVD regulation and what it implies both for IVD manufacturers and for the clinical laboratories.
Link to previous podcasts:
S2E18 – Practical check list of the implementation of an instrument in your lab:https://www.podcastics.com/podcast/episode/s2e18-practical-check-list-of-the-implementation-of-an-instrument-in-your-lab-103649/
S3E4 – All you need to know about instrument validation: https://www.podcastics.com/podcast...2022-06-0711 min
Ask Stago (english version)S3E5 - Should we handle veterinary citrated blood samples like human ones?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Daniel Pilbeam, from the Clinical Pathology Laboratory at UVet in Melbourne will help us understand the common points and differences between veterinary and human hemostasis, and what should be critically assessed.
Previous episodes in relation to the topic:
AskStago episode #9 (season 1): How to manage HIL samples in the coagulation laboratory?
Literature sources:
John W. Harvey, Veterinary Hematology, Chapter 7 - Evaluation of Hemostasis: Coagulation and Platelet Disor...2022-05-0309 min
Ask Stago (english version)S3E4 - All you need to know about instrument validation.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Kaitlyn Pelc will explain further the different steps to validate an instrument at the installation.
Previous episodes in relation to the topic:
S2E18 – Practical check list of the implementation of an instrument in your lab: https://www.podcastics.com/podcast/episode/s2e18-practical-check-list-of-the-implementation-of-an-instrument-in-your-lab-103649/
S2E3 – How to establish and control the reference range of my assay: https://www.podcastics.com/podcast/episode/s2e3-how-to-establish-and-control-the-reference-range-of-my-assay-60155/
S2E2 - How to cali...2022-04-0510 min
Ask Stago (english version)S3E3 - Demystifying platelet aggregometryWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today’s episode, our guest David Courtois will explain further what is platelet aggregometry, how to measure it and in which indications it is useful.
Literature sources:
Born GVR. Aggregation of blood platelets by adenosine disphosphate and its reversal. Nature 1962; 194: 927 – 929.
O’Brien JR. Platelet aggregation. II. Some results from a new method of study. J Clin Pathol 1962; 15: 452-458.
Caen JP, Michel H. Platelet shape change and aggregation. Nature 1972; 240 (5377): 148-149.
Holmsen H. Platelet metabolism and activat...2022-03-0110 min
Ask Stago (english version)S3E2 - EQA, a valuable tool for laboratories.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert Charlotte Parent, Marketing product manager, will talk with us about the EQA. A valuable tool to ensure the quality of laboratory results.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Literature sources:
Ask Stago season 1 episode 3: eIQC and EQA: benefits and differences https://www.podcastics.com/podcast/episode/3-eiqc-and-eqa-benefits-and-differences-35848/
ISO 15189:2012, Medical laboratories — Requir...2022-02-0106 min
Ask Stago (english version)S3E1 - Heparin induced thrombocytopenia: making it clear.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Dr Caroline Vayne from Tours University Hospital in France, gives us an overview on heparin induced thrombocytopenia.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more:
Gruel Y, Vayne C, Rollin J, Weber P, Faille D, Bauters A, Macchi L, Alhenc-Gelas M, Lebreton A, De Maistre E, Voisin S, Gouilleux-Gruart V...2022-01-0412 min
Ask Stago (english version)S2E19 - HTA and value of diagnostic informationWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our co-host Audrey Carlo will share her understanding on what is HTA and why Value of Diagnostic Information should be further recognized.
Literature sources:
Wurcel V, Cicchetti A, Garrison L, Kip MMA, Koffijberg H, Kolbe A, Leeflang MMG, Merlin T, Mestre-Ferrandiz J, Oortwijn W, Oosterwijk C, Tunis S, Zamora B. The Value of Diagnostic Information in Personalised Healthcare: A Comprehensive Concept to Facilitate Bringing This Technology into Healthcare Systems. Public Health Genomics. 2019;22(1-2):8-1...2021-12-0709 min
Ask Stago (english version)S2E18 - Practical check list of the implementation of an instrument in your labWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our expert Pauline Vasselon, US & Projects Registration Coordinator within Stago Market Access team, will provide us the key steps to implement a new instrument in your laboratory.
Literature sources:
ISO 15189 Medical laboratories — Requirements for quality and competence
ISO 22870:2010 Intelligent transport systems — Devices to aid reverse manoeuvres — Extended-range backing aid systems (ERBA)
CLSI Measurement Procedure Comparison and Bias Estimation Using Patient Samples, 3rd Edition, CLSI document EP09c, Wayne PA, 2018.
CLSI Evaluation of Precision of Quantitative Measuremen...2021-11-0209 min
Ask Stago (english version)S2E17 - World Thrombosis DayWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Dr Stephan Moll, will give a hint of his webinar entitled “The Patient with Venous Thrombosis – Practical Points for the Laboratorian and the Clinician”.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more:
Detailed DVT/PE brochure for patients: Moll S, Waldron B. DVT and PE: Information for newly diagnosed patients. Clot Connect...2021-10-0511 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E6 - Comment gérer les échantillons HIL au laboratoire d’hémostase ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec notre expert Frédéric Brutto, responsable de gamme, Cécile Hourquet et Audrey Carlo s'interrogeront sur les interférences HIL et comment le laboratoire de coagulation peut les gérer.
Pour en savoir plus :
Lippi G et al., Interference of blood cell lysis on routine coagulation testing. Arch Pathol Lab Med. 2006;130(2):181-4
Woolley A et al., Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser. Int J Lab Hematol. 2016; 38(4): 375-8...2021-09-1607 min
Ask Stago (english version)S2E16 - DOAC measurement: how and what for?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Jonathan Douxfils, CEO at QUALIblood SA and Professor at the University of Namur / Department of Pharmacy, will detail with us the current recommendation on how to measure direct oral anticoagulants and in which clinical situation this information is relevant and useful..
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more - Literature sources:
Ber...2021-09-0711 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E5 - Qu’est-ce que la sensibilité et la spécificité d’un test diagnostique ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec Lydie Nicoud, directrice de la conception et du développement des applications biologiques, Cécile Hourquet et Audrey Carlo tenteront de mieux comprendre la sensibilité et la spécificité d’un test de diagnostic in vitro, à travers quelques exemples
Pour en savoir plus :
CLSI, Quantitative D-dimer for the Exclusion of Venous Thromboembolic Disease, CLSI document H59-A, Wayne PA; Clinical Laboratory Standards Institute 2011
Valentine Minet, Jean-Michel Dogné, and François Mullier, Functional Assays in the Diagnosis of Heparin-Ind...2021-08-1906 min
Ask Stago (english version)S2E15 - Quality controls: how to establish the QC ranges?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our expert Arnaud Rouvière, Global process – Service manager, will provide us all the current recommendations to establish your Quality control ranges.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more - Previous mentioned podcast :
Previous episode with Arnaud Rouvière : S1E7 How to determine the mean normal prothrombin time
Learn more about the externaliz...2021-08-0308 min
Ask Stago (english version)S2E14 - Oral contraception and thrombotic riskWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Laure Morimont, Project leader at QUALIblood SA, will detail with us the current knowledge on thrombotic risk under hormonal therapy and how this can be assessed.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more ⬇️
Literature sources:
de Bastos M, Stegeman BH, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, Dekkers OM. Combined oral contracep...2021-07-0608 min
Ask Stago (english version)S2E13 - Why is the lab turning digital?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our co-host Cécile Hourquet, Product Line Manager for eSolutions and services, will come to talk about the digitalization of the laboratories.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on...2021-06-2207 min
Ask Stago (english version)S2E12 - Demystifying measurement uncertaintyWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in coagulation.
In today episode, Stephen MacDonald, Principal Clinical Scientist from Cambridge University Hospital, will demystify the process of Measurement Uncertainty determination.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
To learn more:
Go on the websites 👉 https://pathologyuncertainty.com/
👉 https://www.pathologymu.com/
👉 https://pathologymu.teachable.com/
Follow there Twitter https://twitter.com/pathologyMU?
Literature:
ISO/TS 20914: 2019 Medical laboratories –...2021-06-0809 min
Ask Stago (english version)S2E11 - What is thrombin generation?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our expert Marisa Ninivaggi, research project leader at Synapse research institute, will explain us what is thrombin generation.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
Learn more 👇
Literature sources:
Castoldi E, Rosing J. Thrombin generation tests. Thromb Res. 2011 Feb;127 Suppl 3:S21-5. doi: 10.1016/S0049-3848(11)70007-X
Baglin T. The measurement and application of thrombin generation. Br J Haemat...2021-05-2509 min
Ask Stago (english version)S2E10 - How to manage lot conversion in your daily lab management?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our expert Rachael Lamma, a member of our US technical support specialist team, will explain how to handle lot conversion in the daily laboratory organization.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
Learn more 👇
Literature sources:
College of American Pathologists. All Common Checklist. Northfield, IL: College of American Pathologists; 2020
CLSI. User Evaluation of Between-Reagent Lot Variation; Approved Gu...2021-05-1109 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E1 - Différencier le contrôle interne de qualité externalisé et l’Evaluation Externe de la QualitéBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Minh-Lan Nguyen, responsable de gamme pour MyExpertQC, nous aide à différencier et à comprendre l'objectif des programmes de contrôle interne de qualité externalisé (CIQe) et l’évaluation externe de la qualité externe (EEQ).
Pour en savoir plus :
SPECTRA BIOLOGIE n° 229 • Juin - Juillet 2017 http://www.spectrabiologie.fr/wp-content/uploads/2018/02/PUBLI-STAGO-SB229_V5.pdf
SH-GTA-14
Norme ISO 15189
Le contenu est de nature scientifique et technique. Il se veut un outil pédagogique pour les professionnels de laboratoire et les sujets...2021-04-2706 min
Ask Stago (english version)S2E9 - When and how to perform thrombophilia testingWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our expert our expert François Depasse, Clinical development Director, will help us to clarify when thrombophilia testing is appropriate and how to perform it according to international standards.
As usual, don’t forget to send any question you may have to ask@stago.com we will be glad to answer to it.
Literature sources:
https://www.cochranelibrary.com/advanced-search/mesh;jsessionid=DED8CB403679070FD38E81E38E5A7ECA accessed March 17, 2021
Montagn...2021-04-2712 min
Ask Stago (english version)S2E8 - World Hemophilia DayWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our expert Paul, in honor of the upcoming World Hemophilia Day, taking place April 17, will return to our podcast series to cover clinical laboratory testing approaches for patients with inherited or acquired haemophilia.
Literature sources:
Iorio A, Stonebraker JS, Chambost H, Makris M, Coffin D, Herr C, et al.; Data and Demographics Committee of the World Federation of Hemophilia. Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries...2021-04-1314 min
Ask Stago (english version)S2E7 - APTT, not a one-for-all-purposes reagentWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Thomas, is covering with us the usages of APTT testing.
Literature sources:
Toulon, P., Eloit, Y., Smahi, M., Sigaud, C., Jambou, D., Fischer, F. and Appert‐Flory, A. (2016), In vitro sensitivity of different activated partial thromboplastin time reagents to mild clotting factor deficiencies. Int. Jnl. Lab. Hem., 38: 389-396. https://doi.org/10.1111/ijlh.12499
CLSI One-stage Prothrombin Time (PT) test and Activated Partial Thromboplastin Time (APTT) test; Approved guideline - second edition. CLSI document H47-A2 Wayne, P...2021-03-3010 min
Ask Stago (english version)S2E6 - Prothrombin Time routine does not mean "simple"Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert Pierre Bourgeat, will discuss about the Prothrombin time reagent characteristics with a specific focus on the ISI and the type of activators.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
To learn more:
Listen to our podcast about MNPT determination: #7 How to determine the mean normal prothrombin time
View the Webinar of Ian Jenning on stagowe...2021-03-1609 min
Ask Stago (english version)S2E5 - How to collect and prepare the coagulation samples properly?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Vicki, will give you all her tips to collect and prepare you sample in the best way. From sample, material or storage be sure to provide valid sample to your lab. A podcast to share with your colleague, nurses or any person in charge of the preparation of the sample in your facility.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
2021-03-0210 min
Ask Stago (english version)S2E4 - How to determine factor levels in hemophilia?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Alex, will discuss with us how to determine factor levels in hemophilia patients.
Literature sources:
Alfonso Iorio,Jeffrey S. Stonebraker, Hervé Chambost, et al. Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries. Ann Intern Med.2019;171:540-546. [Epub ahead of print 10 September 2019]. doi:10.7326/M19-1208
Blanchette, VS, Key, NS, Ljung, LR, Manco‐Johnson, MJ, van Den Berg, HM, Srivastava, A, for the Subcommittee on Factor VIII, Factor IX...2021-02-1608 min
Ask Stago (english version)S2E3 - How to establish and control the reference range of my assay?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Tara Simpson, will cover with us how to establish and control an assay reference range.
Literature sources:
Henny J. Établissement et validation des intervalles de référence au laboratoire de biologie médicale. Ann Biol Clin 2011 ; 69(2) : 229-37 doi:10.1684/abc.2011.0537
Gardiner, C, Coleman, R, de Maat, MPM, et al. International Council for Standardization in Haematology (ICSH) laboratory guidance for the evaluation of haemostasis analyser‐reagent test systems. Part 1: Instrument‐specific issues and commonly used coagula...2021-02-0209 min
Ask Stago (english version)S2E2 - How to calibrate your reagent as a pro.Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today episode, our expert Draga, will give you all her tips to have the perfect calibration.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2021-01-1909 min
Ask Stago (english version)S2E1 - Whole Blood Viscoelastic Testing (VET)Welcome to Ask Stago, the weekly podcast about hemostasis.
This week, Cécile Hourquet and Audrey Carlo will discuss about viscoelastic testing and the usage of it with our expert Wim Houdijk.
Literature:
Hartert H. Blutgerinnungsstudien mit der Thrombelastographie, einem neuen Untersuchungsverfahren.Klin Wochenschr. 1948;26:577-583.
Sayce AC, Neal MD, Leeper CM. Viscoelastic monitoring in trauma resuscitation Transfusion. 2020;60 (Suppl 6):S33-S51.
Agarwal S, Abdelmotieleb M. Viscoelastic testing in cardiac surgery. Transfusion. 2020;60 (Suppl 6):S52-S60.
Tetsuro Sakai.Viscoelastic testing in liver transplantation. Transfusion. 2020;60 (Suppl 6):S61-S69.
Waters JH. The role of viscoelastic testing in the management of the parturient. Tra...2021-01-0510 min
Ask Stago (english version)#15 Disseminated Intravascular Coagulation (DIC) and fibrin related markersWelcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.
This week, with our expert Paul Riley, Scientific Business Development Manager, Cécile Hourquet and Audrey Carlo will cover the usage of fibrin related markers in the diagnosis of disseminated intravascular coagulopathy.
Litterature:
Baglin T. Disseminated intravascular coagulation: diagnosis and treatment. BMJ 1996; 312: 683-7
Iba T, Di Nisio M, Thachil J, Wada H, Asakura H, Sato K, Kitamura N, Saitoh D. Revision of the Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) diagnostic criteria using antithrombin activity. Crit Care. 2016 Sep 14;20:287
Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi...2020-12-2208 min
Ask Stago (english version)#14 How to be more productive (Part. 3): WorkcellWelcome to Ask Stago, weekly podcast dedicated to providing expert answers to your expert questions in coagulation.
This week, thanks to their expert Alexandre Rousseaux, Cécile Hourquet and Audrey Carlo will question how to be more productive in the lab using a workcell.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-12-1507 min
Ask Stago (english version)#13 The Lupus Anticoagulant diagnosis work upWelcome to Ask Stago, the weekly podcast dedicated to providing expert answers to your expert questions in coagulation.
This week, with our expert Lisa Gannon, product line manager, Cécile Hourquet and Audrey Carlo will question how to accurately perform an Lupus Anticoagulant diagnosis work up in the laboratory.
Sources:
Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, De Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb H...2020-12-0809 min
Ask Stago (english version)#12 How to be more productive (Part. 2): the Lean and the Six sigmaWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
On today’s episode, thanks to our expert Andres Ramirez, discover the part 2 of our series “how to be more productive” with a special episode about Lean and Six sigma workflow analysis.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-12-0109 min
Ask Stago (english version)#11 – Monitoring of UFH: APTT or Anti-Xa?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In our episode this week, we will discuss with François Depasse, our Clinical Development Director, about the monitoring of UFH and the appropriate tool to do it: APTT or anti-Xa activity?
Sources:
Johnson EA, Mullboy B. The molecular weight range of commercial heparin preparations. Carbohydr Res 1976; 51: 119-127
Hirsh J, Raschke R, Heparin and Low-molecular-weight heparin : the Seventh ACCP Conference on Antithrombotic and thrombolytic therapy. CHEST 2004; 126 (suppl 3): 188S-203S.
Basu D, Gallus A, Hirsh J, Cade J. A prospective study of...2020-11-2408 min
Ask Stago (english version)#10 How to be more productive (Part 1): implementation of a rules engineWelcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.
In today’s episode, with our expert Draga Tchipeva, international application specialist, Cécile Hourquet and Audrey Carlo will start questioning how we can help the laboratory to become more productive with some middleware solutions: rules engines.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-11-1708 min
Ask Stago (english version)#9 How to manage HIL samples in the coagulation laboratory?Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals. This week, with our expert Frédéric Brutto, product line manager, Cécile Hourquet and Audrey Carlo will question HIL interferences and how the coagulation laboratory can handle them.
Sources:
Lippi G et al., Interference of blood cell lysis on routine coagulation testing. Arch Pathol Lab Med. 2006;130(2):181-4
Woolley A et al., Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser. Int J Lab Hematol. 2016; 38(4): 375-88
Plebani M, Quality Indicators to Detect Pre-Analytical Errors in Laboratory Testing, Clin Biochem Rev 2012; 3: 85-88. ...2020-11-1007 min
Ask Stago (english version)#8 What are sensitivity and specificity performances of a diagnostic assay?Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals
In today’s episode, with Lydie Nicoud, Director of Design and Biological Applications development, Cécile Hourquet and Audrey Carlo will try to better understand sensitivity and specificity of a diagnostic test, through some examples.
Sources:
CLSI, Quantitative D-dimer for the Exclusion of Venous Thromboembolic Disease, CLSI document H59-A, Wayne PA; Clinical Laboratory Standards Institute 2011
Valentine Minet, Jean-Michel Dogné, and François Mullier, Functional Assays in the Diagnosis of Heparin-Induced Thrombocytopenia: A Review Molecules 22, no. 4 (April 11, 2017): 617, https://doi.org/10.3390/molecules22040617.
Cuker A, Arepally GM, Chong BH, et al...2020-11-0306 min
Ask Stago (english version)#7 How to determine the mean normal prothrombin timeWelcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.
In today’s episode, we will provide you our best tips and tricks to calculate the mean normal prothrombin time for INR assay. To do so, Cécile Hourquet and Audrey Carlo are pleased to welcome Arnaud Rouvière, Manager of the International Application Engineer team of Stago.
Source: WHO technical report series ; no. 979, 2013
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate2020-10-2707 min
Ask Stago (english version)#6 Cybersecurity & Clinical laboratoriesWelcome to Ask Stago, the Podcast providing expert answers to your expert questions.
In today’s episode, our cybersecurity referent Alexandre Rousseaux will explain us how cybersecurity is impacting lab practices every day and why we are all talking about it.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-10-2006 min
Ask Stago (english version)#5 World Thrombosis Day 2020 - Part. 1 DebraWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.
Get involved in the WTD movemen...2020-10-1310 min
Ask Stago (english version)#5 World Thrombosis Day 2020 - Part. 2 ToddWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.
Get involved in the WTD movemen...2020-10-1309 min
Ask Stago (english version)#5 World Thrombosis Day 2020 - Part. 3 ChrisWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.
Get involved in the WTD movemen...2020-10-1309 min
Ask Stago (english version)#4 D-Dimer and its cut-offs for VTE exclusionWelcome to Ask Stago, the Podcast providing expert answers to your expert questions.
In today’s episode, with François Depasse our Clinical Development Director, we will discuss the selection of a cut-off for D-dimer assay in venous thromboembolism exclusion diagnosis.
Sources: Pernod G, Maignan M, Marlu R. Questioning the use of an age-adjusted D-dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies: comment. J Thromb Haemost 2016; 14: 2553–4.
Stavros V Konstantinides, Guy Meyer, Cecilia Becattini, Héctor Bueno, Geert-Jan Geersing, Veli-Pekka Harjola, Menno V Huisman, Marc Humbert, Catriona Sian Jennings, David Jiménez...2020-10-0607 min
Ask Stago (english version)#3 eIQC and EQA: benefits and differencesWelcome to Ask Stago, the Podcast providing expert answers to your expert questions.
In today’s episode, thanks Minh-Lan Nguyen, product line manager, we will help you to differentiate and understand the goal of the externalized internal quality control (eIQC) and external quality assessment programs (EQA).
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-09-2908 min
Ask Stago (english version)#2 Coagulation abnormalities in COVID-19 patientsWelcome to Ask Stago, the podcast providing expert answers to your expert questions.
In this week ‘s episode with our expert François Hamon, we will provide you information about how infection with COVID-19 affects coagulation and how these coagulation abnormalities should be monitored.
Sources: Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost 2020;18:844–7.
Moores LK, Tritschler T, Brosnahan S et al, Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease 2019, CHEST Guideline and Expert Panel Report, CHEST 2020; 15...2020-09-2409 min
Ask Stago (english version)#1 COVID-19: contamination and risks in handling samplesProvide guidelines about the best practices to handle samples from COVID-19 patients and answer FAQ questions from the field about general management such as preparation of sample and HIL interferences induced by COVID-19.
Sources: Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA. 2020;323(18):1843–1844. doi:10.1001/jama.2020.3786
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-09-1608 min