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Chris Masterjohn, PhD
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Mastering Nutrition
Biotin’s Health Benefits: Way Beyond Hair and Nails
Most people who take biotin take it for their hair and nails. Yet biotin does much more than this. Learn what to use it for, how much to take, and how to avoid adverse effects in less than ten minutes. Read the written and fully referenced version here: https://chrismasterjohnphd.substack.com/p/biotins-health-benefits-way-beyond Get my short and sweet tips on each nutrient in the Cliff Notes here: https://chris-masterjohn-phd.myshopify.com/products/the-vitamins-and-minerals-101-cliff-notes It's free to Masterpass members here: https://chrismasterjohnphd.substack.com/p/paid-subscribers-now-have-free-access
2023-10-26
07 min
Mastering Nutrition
Nutrition in Neuroscience Part 2 | Mastering Nutrition #41
Part 2 of how NUTRITION has a HUGE impact on your BRAIN! Everything in your brain is something you ate, something you made from something you ate, or, in a few cases, something your mother ate. Nutrition impacts your mental and emotional health, the function of your five senses, and your conscious and unconscious control over your body movements. Join me as I lead you in a safari through the textbook, “Neuroscience,” pointing out along the way all the interesting connections to nutrition. Listen in for part 2 on the NEUROTRANSMITTERS! 0:00:37 Cliff Notes 0:04:15 Overview of neurotransmitters 0:06:55 Glutamate is the primary excitatory neurotransmitter. 0:14:08 De novo glutamate...
2022-06-09
1h 39
Mastering Nutrition
NEW! Version 7 of the COVID Guide!
Newly updated September 25, 2021, and now in Version 7: https://chris-masterjohn-phd.myshopify.com/products/the-food-and-supplement-guide-for-the-coronavirus This guide provides my recommendations for nutritional and herbal defense against COVID. This version covers 41 randomized controlled trials, which are the gold standard of evidence, as well as many other studies providing context for interpreting the trials. Since much of this research is recent, not all of it is peer-reviewed. However, I have used my own expertise in nutritional sciences and extensive experience evaluating research to fully review the quality of this evidence myself. This protocol represents the best of science-backed strategies...
2021-09-26
07 min
Mastering Nutrition
What are optimal levels of B12? | Masterjohn Q&A Files #157
Question: What are optimal levels of B12? So there's a paper called the Pathophysiology of Elevated Vitamin B12 in clinical practice that PM Schoenfeld, another Masterpass member, had given me. And this paper is very interesting because it identifies a bunch of things that high B12 can be an indicator of, not a causal factor in but an indicator of problems. And it also disputes the low end of the range. So according to this paper, we really want B12 levels above 400 picograms per milliliter, which is 295 picomoles per liter. I believe picograms per liter is what...
2020-12-14
11 min
Mastering Nutrition
Are GABA or methylation support useful for panic attacks? | Masterjohn Q&A Files #156
Question: Are GABA or methylation support useful for panic attacks? I think anything that increases GABA activity is probably going to slow down anxiety and panic. I think that's clear just from the drugs that are used to treat an anxiety, or panic disorder. Xanax is used for that purpose. So I do think that working on nutritional support around GABA makes sense, but I also would look at histamine, because histamine is an alertness signal, but I think in very excessive amounts histamine is a panic signal. GABA might help move focus from one...
2020-12-11
14 min
Mastering Nutrition
Is increasing reactive oxygen species a good strategy for appetite control? | Masterjohn Q&A Files #155
Question: Is increasing reactive oxygen species a good strategy for appetite control?Is that going to cause satiety in the brain? Maybe. I haven't studied that. I think Stephan Guyenet would be a great person to talk to about that. It wouldn't surprise me in the sense that if you want to shut down energy coming into the cell, why wouldn't you also want, at some bigger level, to shut down energy input into the body? I guess that makes sense. But I've mostly studied this in the case of outside the brain, peripherally, what is it...
2020-12-10
17 min
Mastering Nutrition
What’s the best way to increase ferritin? | Masterjohn Q&A Files #154
Question: What’s the best way to increase ferritin?If you're taking an iron chelate supplement then you should probably take it with a carnivore meal. Vitamin C and a few other ones, folate, are not really vegan nutrients but they're very plant-oriented nutrients in terms of what's the thing you're probably going to add to your diet that's going to help. And so I really feel like if I had iron deficiency anemia, I would probably just spend four weeks on a carnivore diet that was rich in red meat and if I really wanted to ju...
2020-12-09
06 min
Mastering Nutrition
What to eat for a 35-year-old vegan woman with hypothyroidism and low zinc levels? | Masterjohn Q&A Files #153
Question: What to eat for a 35-year-old vegan woman with hypothyroidism and low zinc levels? I think a vegan with poor zinc levels should supplement with zinc. You know, it's one thing if you have a vegan whose diet just happens to provide good zinc status, despite the fact that their diet is dramatically lower in total zinc than an omnivore who eats a lot of red meat or seafood, particularly oysters, and that the bioavailability of zinc from those foods is dramatically less. So a vegan probably needs twice as much zinc...
2020-12-08
12 min
Mastering Nutrition
Are the concerns about cyanocobalamin exaggerated? | Masterjohn Q&A Files #152
Question: Are the concerns about cyanocobalamin exaggerated? I'm not sure what people have said about the dangers. I know that I have been a critic of cyanocobalamin relative to other forms of B12 and then, other people may have used something I said maybe in an exaggerated way. And then there might be just much marketing that I haven't actually been exposed to where people have come up with their own marketing claims around other forms of B12. So my opinion is basically as follows: number one, the amount of cyanide that would be released...
2020-12-07
08 min
Mastering Nutrition
What’s a better nasal spray, Sterimar or povidone-iodine? | Masterjohn Q&A Files #151
Question: What’s a better nasal spray, Sterimar or povidone-iodine? It's hard to say. So the Povidone-iodine obviously has some contraindications and it has contraindications mostly because it's been so commonly used in a medical setting and therefore has so much known about its safety and risk profile and I don't have any particular reason to think that the Sterimar is unsafe in any context. And I used it a lot. The only thing I can say anecdotally is I've used the Povidone-iodine intra nasally, and I've used the Sterimar spray intra nasally. And I feel li...
2020-12-04
09 min
Mastering Nutrition
Do postmenopausal women need to worry about iron overload? | Masterjohn Q&A Files #150
Question: Do postmenopausal women need to worry about iron overload?Generally, it's not men who are necessarily predisposed to iron buildup. It’s men with some genetic predisposition to that, so maybe less than 10% of men. But yeah, postmenopausal women with the same genetics will, like men, be vulnerable to that. When you stop menstruating, you essentially become like a man in terms of your ability to accumulate iron. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to the...
2020-12-03
03 min
Mastering Nutrition
Should NAC supplementation be pulsed? | Masterjohn Q&A Files #149
Question: Should NAC supplementation be pulsed?So, yes, boost glutathione. It might bring glutathione down. It's speculative that you could pulse it to avoid that. But even supplementing oral glutathione for 6 months was shown to not affect glutathione production. And certainly, oral glutathione is going to have more of a negative feedback loop than a glutathione precursor. So, I am not too worried about it. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions...
2020-12-02
03 min
Mastering Nutrition
Why would my threonine levels be low? | Masterjohn Q&A Files #148
Question: Why would my threonine levels be low? The two things I can think of are increased gluconeogenesis and increased conversion of methylglyoxal, both of which I would expect to be driven by a low carbohydrate diet. Then of course, it could also be not enough protein consumption. But if it's why threonine is being metabolized, I'm gonna be thinking of a low carbohydrate diet. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions...
2020-12-01
02 min
Mastering Nutrition
What’s the best alcohol to microdose? | Masterjohn Q&A Files #147
Question: What’s the best alcohol to microdose? I prefer red wine on a taste, and tradition, and aesthetic basis. Just for background, I think Half a drink to a drink a day is probably the net maximal benefit for alcohol and that can be averaged. It doesn’t have to be every day. And that’s the main thing. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features...
2020-11-30
03 min
Mastering Nutrition
What’s the best nutrition for panic and anxiety? | Masterjohn Q&A Files #146
Question: What’s the best nutrition for panic and anxiety?Methylation is overwhelmingly important. I do think that other factors impacting dopamine can be relevant in the sense that the main way that methylation regulates mental rigidity is through decreasing the pool of tonic dopamine, which favors mental flexibility. And so, you can also favor mental flexibility by increasing the activity of dopamine receptors that mediate the basic response dopamine. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to t...
2020-11-27
07 min
Mastering Nutrition
What determines the absorption of nutrients? | Masterjohn Q&A Files #145
Question: What determines the absorption of nutrients? This is a gigantic question because what determines the absorption of any given nutrient is independent for that nutrient. And so, it’s different for every nutrient. And we just don't have that level of data to drive modeling of absorption of other nutrients in an accurate way. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and...
2020-11-26
07 min
Mastering Nutrition
Do low serine levels require IV supplements? | Masterjohn Q&A Files #144
Question: Do low serine levels require IV supplements?You're probably just depleting serine through the CBS pathway and just eat more protein and consider supplementing glycine or collagen along with it. I don't see why that would require IV supplements. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/ma...
2020-11-25
02 min
Mastering Nutrition
How to fix high iron and calcium, low copper and magnesium, without blood donation? | Masterjohn Q&A Files #143
Question: How to fix high iron and calcium, low copper and magnesium, without blood donation? Your only options for decreasing iron levels are to eat a low meat vegetarian diet high in vegetables, nuts, seeds, and whole grains. That's probably your best bet. But the thing is, a very vegetable rich diet is gonna be pretty high in copper. And it's going to be high in iron too, but it's gonna be very poorly absorbable iron. And you know, especially if you eat a lot of whole grains, nuts, seeds, and legumes, you can get...
2020-11-24
08 min
Mastering Nutrition
How much time should separate my zinc supplements and nut consumption? | Masterjohn Q&A Files #142
Question: How much time should separate my zinc supplements and nut consumption? So, phytate primarily inhibits absorption of zinc and iron. I think you're gonna have a much lower probability of zinc encountering phytate if you take the zinc 2 hours after eating the phytate than if you take the zinc while you eat the phytate. But you know, if you're trying to be maximally conscientious, 3 hours after the meal. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass...
2020-11-23
05 min
Mastering Nutrition
What’s the safe use of an iodine nasal spray? | Masterjohn Q&A Files #141
Question: What’s the safe use of an iodine nasal spray?So, the iodine in the food and supplement guide for the coronavirus most recent version, I included iodine as a nasal spray. It's very important to look at the percentages. And so, 0.5% is the concentration recommended and that means that if you get a 10% solution, which is the most common one, you want to dilute it down 20-fold, which means taking one part of the 10% solution 19 parts water. If you have a different percentage starting solution, you wanna dilute it differently. And it's critically important that yo...
2020-11-20
06 min
Mastering Nutrition
Why would ferritin be extremely high when transferrin saturation is low? | Masterjohn Q&A Files #140
Question: Why would ferritin be extremely high when transferrin saturation is low? Ferritin as a potential indicator of iron overload should not be anywhere near the level that was set to try to rule in biopsy provable hemochromatosis that is just a profoundly negligent approach to setting the range for ferritin. Now, I think part of what has stopped, you know— This mostly is a problem of the binary diagnostic mindset of conventional medicine. So, I'm not saying that this mindset is not useful. It is tremendously useful, but too many people confuse it for a reality wh...
2020-11-19
10 min
Mastering Nutrition
Can carnitine be used for fatty liver instead of choline? | Masterjohn Q&A Files #139
Question: Can carnitine be used for fatty liver instead of choline? The role of choline and the role of carnitine have nothing to do with one another. Choline is going to help move fat out of the liver. Carnitine is going to help fat get into the mitochondria to be burned for energy. So, first of all, I think one thing that’s important to note is that you're gonna get more bang for the buck by fixing the things that are wrong rather than pulling on levers that are working perfectly fine. If...
2020-11-18
15 min
Mastering Nutrition
Is it OK to drink a pint of Gerolsteiner mineral water a day? | Masterjohn Q&A Files #138
Question: Is it OK to drink a pint of Gerolsteiner mineral water a day?It’s significantly less than a bottle. I guess conceivably if you're also drinking a lot of milk, or eating a lot of cheese, or supplementing with calcium, or taking bone meal powder, I guess you can get too much calcium. I wouldn’t really worry about it from 1 pint. I do think that the main concern with carbonated beverages of any type is that you have too much acid running over your teeth a lot. So, I think it's wise to drink this...
2020-11-17
05 min
Mastering Nutrition
Cataracts: what are the roles of methylglyoxal and polyols? | Masterjohn Q&A Files #137
Question: Cataracts: what are the roles of methylglyoxal and polyols?Is the polyol pathway activation and methylglyoxal independent causes of cataract formation or are they related to one another? And the answer is a little bit of both. You know, if independent means unrelated, then they’re related. Not independent. But they are independent in the sense that you could have more of one. You know, you could do something that increases one and not the other or at least disproportionately increases one versus the other. So, the polyol pathway, I think the best way to describe th...
2020-11-16
10 min
Mastering Nutrition
Is the sugar in Life Extension Enhanced Zinc Acetate lozenges a problem? | Masterjohn Q&A Files #136
Question: Is the sugar in Life Extension Enhanced Zinc Acetate lozenges a problem?In that kind of protocol attuned to the progress of the potential cold, I find no alternative is more effective than the zinc acetate lozenges. And so, therefore, I'm willing to consume 40 or 60 grams of sugar for like 1 day or 2 days and then have it taper off granted— I might have a totally different attitude if I had diabetes. But from a cost-benefit analysis, I don't think consuming 40 grams of sugar once for a healthy person is going to cause any permanent damage. It's no...
2020-11-13
12 min
Mastering Nutrition
If I use SAMe for depression, what do I need for nutritional balance? | Masterjohn Q&A Files #135
Question: If I use SAMe for depression, what do I need for nutritional balance? Nutrition wise, I think the most important thing would be to make sure that you have an adequate glycine status. And you know, I don't know what your background is in terms of other issues, but the glycine buffer system, which is how you buffer excess methyl groups, which is what you would have if you take a large bolus of SAMe.Other nutritional concern would be having enough molybdenum. Generally, you're gonna have enough with 100 mcg a day. If...
2020-11-12
12 min
Mastering Nutrition
Should I take iron every day or use alternate day dosing? | Masterjohn Q&A Files #134
Question: Should I take iron every day or use alternate day dosing?Reference: https://haematologica.org/article/view/9379 So, according to this abstract, in iron depleted women without anemia, oral iron supplements induce an increase in serum hepcidin that persist for 24 hours, decreasing iron absorption from supplements given later on the same or next day. Consequently, iron absorption from supplements is highest if iron is given on alternate days.Bringing this back to a practical level, is it easier for you to maintain a habit of every day dosing or is it easier...
2020-11-11
16 min
Mastering Nutrition
Should I spread my collagen out across my meals? | Masterjohn Q&A Files #133
I'm not sure what the best dosing is given that it hasn't actually been studied fully, but I believe that it was estimated that in the people who have the highest collagen waste during collagen turnover that they can run short of glycine about 60 grams a day whereas I believe the more conservative estimate of glycine requirements based on people that turnover collagen much more efficiently.I would say that as a general rule, you should assume that you want something spread out as much as possible rather than the reverse if you don't have the data...
2020-11-10
07 min
Mastering Nutrition
Where should I buy my chicken products? | Masterjohn Q&A Files #132
Question: Where should I buy my chicken products? You may have local options. And a good place to look for local options would be eatwild.com. I’m assuming it’s still up. That was a great database and probably still is a great database of pasture-raised products of any type. Not just chicken. And then of course, there are the mail order companies that I have exclusive discounts with inside the Masterpass program, most of which sell chicken products. So, White Oak Pastures, North Star Bison who focuses on bison but I believe they have...
2020-11-09
03 min
Mastering Nutrition
Why would blood glucose go up on a low-carb diet? | Masterjohn Q&A Files #131
Question: Why would blood glucose go up on a low-carb diet? When you're adapted to low insulin levels with lower GLUT expression, but you want to get glucose into muscle, you're going to need higher blood glucose levels to do it. I think elevated blood glucose is sufficiently known to be pathological that it would be unwise to assume the sort of more generous interpretation of that as a physiological response. I think it would be a much better approach to do what you need to do to get your blood glucose levels into the healthy...
2020-08-27
02 min
Mastering Nutrition
Why do thyroid levels drop on a low-carb diet? | Masterjohn Q&A Files #130
Question: Why do thyroid levels drop on a low-carb diet? So insulin and leptin are both positive regulators of thyroid hormone, production, and conversion. And generally I do think there's probably a larger effect from thyroid production than peripheral conversion. I'm not too sure about that, but insulin does directly regulate thyroid. It has TSH-like effects on the thyroid gland. It doesn't replicate all of TSH's effects, but it does replicate a portion of them. So basically, more or less, have like TSH amplification with insulin. This Q&A can also be found as part...
2020-08-26
01 min
Mastering Nutrition
Is hydrogen sulfide produced in the gut a bad thing, and what to do about it? | Masterjohn Q&A Files #129
Question: Is hydrogen sulfide produced in the gut a bad thing, and what to do about it?I agree that most people that have this problem have some kind of deranged sulfur metabolism, but I don't see why that makes it a physiological adaptation rather than a pathological condition. The correlation is probably a direct result of the predominance of sulfur-metabolizing bacteria in the gut, which is a bad thing that is actually causing the derangement of sulfur metabolism. Well, you could go the antibiotic route. And I think metronidozole, and let me see if...
2020-08-25
06 min
Mastering Nutrition
What if low-carb makes me wake up to pee? | Masterjohn Q&A Files #128
Question: What if low-carb makes me wake up to pee? I would start by looking at your blood sugar. So I do think it's possible that if your blood sugar. Second of all, it's stimulated by salt. So salt at night might help. Third of all, in order to make it you need copper, vitamin C, and zinc. And then, fourth of all, you need, going past that, I also suggest trying to get deeper sleep. You might want to look at the quality of your sleep. So, I do think generally carbs help people get better s...
2020-08-24
04 min
Mastering Nutrition
How does someone get arachidonic acid and choline without eggs and liver? | Masterjohn Q&A Files #127
Question: How does someone get arachidonic acid and choline without eggs and liver? So apart from liver and egg yolks, I think that it is very difficult to get enough arachidonic acid from food. Yes, GLA might help, but there's actually arachiodonic acid supplements. And for the vegans out there, I don't know if the production process is strictly vegan, but they are derived from a specific mushroom and you can get them on Amazon. So I think supplementing with arachidonic acid is probably the most direct way to do that. And then evening primrose or a...
2020-08-21
03 min
Mastering Nutrition
Nutritional suggestions for SI joint pain and sulfur sensitivity? | Masterjohn Q&A Files #126
Question: Nutritional suggestions for SI joint pain and sulfur sensitivity? So certainly if it's autoimmunity, I'm thinking you might have problems with folate, where you might want to lower folate intake. You might benefit from having more A and D. You might benefit from removing hypothetically pro-inflammatory foods. Magnesium is important. Acid-base balance is important. Citrate is probably helpful. And then on the sulfur issue, molybdenum and manganese are both important for properly dealing with sulfur. And then you might also want to be looking at your gut microbiome as well. This Q&A can...
2020-08-20
02 min
Mastering Nutrition
Long-term shortness of breath after COVID-19: do I need iron? | Masterjohn Q&A Files #124
Question: Long-term shortness of breath after COVID-19: do I need iron?I don't think there's any evidence that iron fuels COVID-19. And it's pretty clear that the systemic inflammation is driving dysregulation of iron in a way that hurts oxygen delivery. So it's very clear that low oxygen delivery is a major feature of COVID. And I think probably the bulk of that is due to clotting, but also inflammation. And if you look at the CRP levels in COVID, like going up to the hundreds. Normally, you want it below one. Your CRP is two or...
2020-08-18
09 min
Mastering Nutrition
Are liposomal supplements really superior? | Masterjohn Q&A Files #123
Question: Are liposomal supplements really superior? I doubt it. So I think the evidence indicates that liposomes don't survive digestion unless they are pegylated, which means that they have polyethylene glycol that's attached to the liposome to protect them from digestion. There are a number of other such modifications that can be made, but I don't think that applies to most liposomal things on the market. So I'm generally very skeptical of the claims that liposomal will offer superior delivery, particularly if they're not being specifically designed to survive digestion, which most are not. ...
2020-08-17
01 min
Mastering Nutrition
Why would I develop shortness of breath on a carnivore diet? | Masterjohn Q&A Files #122
Question: Why would I develop shortness of breath on a carnivore diet? That can happen in scurvy. So given that vitamin C is one of the higher-risk nutrients on a carnivore diet, that would be the first thing that I would look at. I'm glad it was short-lived. I think it's possible that there are vitamin C-sparing effects of a carnivore diet, but they take a little while to kick in. So as you transition, you had a temporary scurvy and then you had adaptations that mitigated that. Certainly it could be many other things, but without...
2020-08-14
01 min
Mastering Nutrition
Is it possible to meet all your nutritional needs on a carnivore diet? | Masterjohn Q&A Files #121
Question: Is it possible to meet all your nutritional needs on a carnivore diet? So the short answer to this question is yes, but the longer answer to this question, as I just went through, is it's quite complicated. I've said it with respect to carnivore diets. I think it's good to look at nutrition, kind of like an economic portfolio. If you are very, very expert, you can know what you're doing in limiting the asset classes you include in your portfolio. So, really know what you're doing. You can do carnivore or v...
2020-08-13
11 min
Mastering Nutrition
Why are medium-chain fatty acids ketogenic even in the presence of carbs? | Masterjohn Q&A Files #120
Question: Why are medium-chain fatty acids ketogenic even in the presence of carbs?It's all about the ratio. We know for a fact that MCT oil is ketogenic even in the presence of pasta, period, end of story. So, the question here is, biochemically, why is it happening? Well, they go into the mitochondria, even in the presence of insulin and a buildup of acetyl CoA over the incoming oxaloacetate. A high acetyl CoA-to-oxaloacetate ratio generates ketones. So the question is that basically this question is why isn't there enough oxaloacetate? So generally...
2020-08-12
12 min
Mastering Nutrition
What measurement of magnesium status is best to use for arrhythmias? | Masterjohn Q&A Files #119
Question: What measurement of magnesium status is best to use for arrhythmias?I assume by "measure" you mean a measurement of nutritional status, in which case I think you want to look at the serum level. think that if you're trying to fix a problem with the serum level, you probably at some point want to look at the red blood cell level and the urine level. One of the ways that magnesium could impact the arrhythmias would be through influencing other minerals, and so I would not recommend just looking at magnesium on its own. You...
2020-08-11
03 min
Mastering Nutrition
Is subclinical thiamine deficiency a contributor to many diseases? | Masterjohn Q&A Files #118
Question: Is subclinical thiamine deficiency a contributor to many diseases?So in terms of like in terms of subclinical deficiency, is it common, does it exist? It is hard to answer because, as usual, most of the data that's clear is on severe deficiencies, but there are some studies. I wouldn't say that there's a huge body of literature. There are some studies suggesting that even if you take a group of people who have some blood sugar issues and they are not thiamine deficient by classical standards, you can give them a hundred milligrams of thiamine...
2020-08-10
07 min
Mastering Nutrition
Should a female focus on lowering DHT to avoid pattern baldness? | Masterjohn Q&A Files #117
Question: Should a female focus on lowering DHT to avoid pattern baldness? Carrie: DHT is only one of the alpha metabolites. If you just do it in serum, that's usually what everyone test, but there are some other big ones, androsterone, and 5 alpha-androstanediol is another big one that you can test in your intestine. DHT maybe low in women, but I'll see the androsterone be really elevated which is more common in women I see. In which case, yes, you can decrease testosterone, but you need to get yourself sort of off the 5 alpha pathway. ...
2020-04-30
02 min
Mastering Nutrition
Is there an optimum number of meals or insulin spikes per day for optimizing thyroid function? | Masterjohn Q&A Files #116
Question: Is there an optimum number of meals or insulin spikes per day for optimizing thyroid function? Assuming that you're controlling for the level of insulin sensitivity on the thyroid gland -- I guess if I had to throw out a wild guess, the free fatty acid concentration is probably mostly relevant when the free fatty acid levels are really high. It's probably not the case that you want to just like -- it's probably -- I don't know. If you go a long time without eating food or you eat like very high fat, very low...
2020-04-29
01 min
Mastering Nutrition
What can be done to reverse hypothyroidism other than taking thyroid medicine? | Masterjohn Q&A Files #115
Question: What can be done to reverse hypothyroidism other than taking thyroid medicine? Chris: I'll throw in a couple things. If you just look at the nutrients needed to make thyroid hormone, you're looking at enough protein in addition to enough iodine. But then also the production of thyroid hormone is a very, very dirty process that requires an enormous amount of antioxidant support. Selenium is very important. But also, if you're looking at antioxidant protection, you're looking at not just things that we think of as dietary antioxidants. But you're looking at protein, zinc, iron, copper...
2020-04-28
10 min
Mastering Nutrition
Why would a woman have no cycle? Why would a woman have an anovulatory cycle? | Masterjohn Q&A Files #114
Question: Why would a woman have no cycle? Why would a woman have an anovulatory cycle? Carrie: Remember, cortisol is very, very, very potent in the brain. If the body perceives itself is under stress, whether it's physical, mental, emotional, environmental, it doesn't matter, then reproduction is not its primary focus anymore. I had been thinking this for a long time. I didn't know how to eloquently say it and then she said it on stage one day. She said, "Ladies, whether you want to or not, I'm sorry, but you were put here to reproduce. Biology...
2020-04-27
05 min
Mastering Nutrition
What to do about premenstrual water retention? | Masterjohn Q&A Files #113
Question: What to do about premenstrual water retention? Chris: I looked at a really good paper that showed that in women who had water retention symptoms with PMS, the main difference in their hormones was that they weren't clearing progesterone as fast from their ovulation-related peak. I was discussing this with a different friend who had found that she would consistently get water retention in response to using progesterone creams. Carrie: A big reason, that we are protected up to the point and then we go through menopause and we'd lose all that estrogen...
2020-04-24
04 min
Mastering Nutrition
Dietary nutritional advice for breast cancer prevention and thoughts on HRT? | Masterjohn Q&A Files #112
Question: Dietary nutritional advice for breast cancer prevention and thoughts on HRT? Carrie: Well, that's probably better for you when it comes to like nutrient ratios and stuff. But I will say working for an estrogen lab, we're looking at phase one and phase two detoxification and what we're trying to assess with estrogen. Men and women, we make estrogen, and then we detox our estrogen. We go through phase one detoxification. Well, it becomes a reactive oxygen species essentially. Then we quickly neutralize it. Our body has these systems in place to protect us. ...
2020-04-23
09 min
Mastering Nutrition
What are causes for night sweats in men?| Masterjohn Q&A Files #111
Question: What are causes for night sweats in men? Carrie: Oh. Well, it can be hormonal just like it can be for women. I test all the same hormones in men. I check their thyroid with night sweats. I definitely even check the same thing. I check cortisol and I do norepinephrine markers with night sweats. This is also assuming that I don't suspect cancer because night sweats can be a key note, especially in men, night sweats can be a key note for cancers, and so I want to make sure I'm not suspicious of that...
2020-04-22
04 min
Mastering Nutrition
With an ovary removed, when should I think about increasing progesterone or estrogen? | Masterjohn Q&A Files #110
Question: With an ovary removed, when should I think about increasing progesterone or estrogen? Carrie: You may actually need more progesterone. Like I was saying in the very beginning of this, that progesterone actually turns into that neurosteroid allopregnanolone, which can cross the blood-brain barrier and bind itself to GABA and affect sleep. It's very calming, obviously relaxing. It's GABA. Carrie: Obviously, there are other things that affect sleep too. If your norepinephrine is going up at night, if you got blood sugar issues, if your cortisol is going up at night -- and norepinephrine...
2020-04-21
03 min
Mastering Nutrition
Why do I wake up early every morning when I’m depressed? | Masterjohn Q&A Files #109
Question: Why do I wake up early every morning when I’m depressed? Carrie: Now, with depression, it's heavily studied if you have an elevated or excessive cortisol awakening response, meaning you go higher, your spike is higher and more dramatic than the average bear, then your risk for morning depression is much higher. The reason for that as we've already touched upon with estrogen and the serotonin versus kynurenine pathway because high excessive glucocorticoids or cortisol can also upregulate the pathway away from serotonin and down towards kynurenine. If you wake up with excessive am...
2020-04-20
08 min
Mastering Nutrition
How does the body make hormones and what nutrients and foods do they need to do this? | Masterjohn Q&A Files #108
Question: How does the body make hormones and what nutrients and foods do they need to do this? Carrie: Now, as far as nutrients go, like I said, cholesterol is the backbone to all of your hormones. Much like the gentleman who said earlier his cholesterol was quite low, it can impact the way and the amount of hormones that you make. The lower your cholesterol is, the tougher time you can have to make hormones. But the more cholesterol you make doesn't necessarily mean you're going to have mass amounts of hormones. It's a very tightly...
2020-04-17
12 min
Mastering Nutrition
Should someone with low testosterone go back on testosterone replacement therapy or wait it out? | Masterjohn Q&A Files #107
Question: Should someone with low testosterone go back on testosterone replacement therapy or wait it out? Carrie: Men have luteinizing hormone just like women do. It comes from the brain. It's what stimulates the testes to make testosterone. If you have low LH, then I know it's a brain problem, not necessarily a testicular problem. If your LH is normal, it's not in the brain. Chris: If the question is how long should he wait, waiting is probably not going to give you any more answers than it was giving you for the last five...
2020-04-16
08 min
Mastering Nutrition
What to do about low libido after a LEEP procedure? | Masterjohn Q&A Files #106
Question: What to do about low libido after a LEEP procedure? Carrie: With the LEEP procedure, so like I was saying, basically it's kind of like a hot knife through butter. They cut away a portion of the cervix. And it depends. Sometimes it's a little portion and sometimes they do what they call like a full big slider right across the face of the cervix. If you remember, for those of you who maybe never seen a cervix, it's shaped like a doughnut. Literally, your cervix is this tiny little pink doughnut and has a hole...
2020-04-15
05 min
Mastering Nutrition
Would a seasonally low vitamin D intake and high calcium intake cause soft tissue calcification? | Masterjohn Q&A Files #105
Question: Would a seasonally low vitamin D intake and high calcium intake cause soft tissue calcification? Chris: Yeah, okay. The end of this question is would the calcium simply be excreted due to the low vitamin D levels. Your vitamin D level being low, the first thing that's going to do and the major thing that's going to do is it's going to lower your calcium absorption. You would have more calcium excreted in the feces as a result of not absorbing it if your vitamin D level is low. However, a high enough calcium intake is...
2020-04-14
05 min
Mastering Nutrition
Question on Iodine, Fatigue, and Detox Reaction. | Masterjohn Q&A Files #104
Question: Question on Iodine, Fatigue, and Detox Reaction. Carrie: Remember, iodine belongs to the halogen family and other halogens can bind onto your PT or tyrosine. I have had this before where patients would take iodine and the iodine will push off the fluoride and the chloride and the bromide off of the tyrosine, and so it binds on and now you have essentially a detox reaction. People will say, "I get headaches. I've broken out in rashes. I'm really tired." Because the other halogens have come off the tyrosine and are now floating around your system.
2020-04-13
06 min
Mastering Nutrition
How to lower Sex Hormone-Binding Globulin (SHBG)? | Masterjohn Q&A Files #103
Question: How to lower Sex Hormone-Binding Globulin (SHBG)? Carrie: SHBG is like bane of my existence. I have no idea how to get SBHG down once it's up. Boy, I actually talk to practitioners about this all the time to figure that out. I would agree that supplements that for SHBG, it's very hit or miss, Tongkat being one of them, DHEA being the other. There are two other ones, stinging nettles and Avena oats. There's like very mild, very weak research about lowering SHBG with nettles and then with Avena. Again, it's like hit or miss...
2020-04-10
08 min
Mastering Nutrition
Why does estrogen regulate tryptophan metabolism? | Masterjohn Q&A Files #102
Question: Why does estrogen regulate tryptophan metabolism? Chris: I think that it's basically the body trying to make sure that the baby has enough niacin because chronic estrogen exposure would occur during pregnancy. When I was doing my niacin research, one thing that I found is that women seem to need more total niacin than men, but they seem to be better at making niacin from protein. What's really interesting is that the studies that were done that were used to make the RDA, there weren't comparisons in men and women, but two of the studies were...
2020-04-09
05 min
Mastering Nutrition
Insomnia is different between people who are and aren't on HRT? | Masterjohn Q&A Files #101
Question: Insomnia is different between people who are and aren't on HRT? Carrie: Yes, sort of. If it's strictly a hormone issue, if she says, "I've never had insomnia. I turned 45 and I got insomnia. And, oh, by the way, I'm also having irregular periods and hot flashes and night sweats and all this stuff," I find that going on HRT generally resolves their insomnia. If they've had insomnia their whole life and, by the way, they're having hormonal issues as well or they're perimenopausal, going on HRT may or may not help their insomnia...
2020-04-08
02 min
Mastering Nutrition
The use of pregnenolone to manage perimenopausal symptoms, particularly insomnia. | Masterjohn Q&A Files #100
Question: The use of pregnenolone to manage perimenopausal symptoms, particularly insomnia. Carrie: Well, so here's the thing about pregnenolone. Oral or sublingual, so if you've got drops or little tables you suck on. Pregnenolone and progesterone, when they go through first pass, so you swallow them and then you go through first pass, they turn into other metabolites. One is called allo, which is short for allopregnanolone. Allo binds to your GABA receptors in your brain. Allo can cross the blood-brain barrier, binds to GABA. GABA, of course, is your calming, relaxing, everything is going to be...
2020-04-07
01 min
Mastering Nutrition
Guidance on what time of day it is best to take T4 and/or T3? | Masterjohn Q&A Files #99
Question: Guidance on what time of day it is best to take T4 and/or T3? Carrie: It actually depends if you're taking immediate release T4 or T3 especially or sustained release because T4 has a much longer half-life which is why we traditionally say to take it in the morning since it helps with energy and metabolism and all those things. Although I do know some people choose to take their T4 at night before bed. But T3 has a very short half-life, and so what I'm finding is some practitioners are now doing what's called...
2020-04-06
02 min
Mastering Nutrition
Does folic acid act differently in the body than natural folate? | Masterjohn Q&A Files #68
Question: Does folic acid act differently in the body than natural folate? | Masterjohn Q&A Files #68They don't really. Everything that is said bad about folic acid is sort of true to an extent but has been completely exaggerated in some circles. What happens is you have an enzyme called dihydrofolate reductase, or DHFR. Its purpose is not to metabolize synthetic folic acid obviously because that folic acid molecule doesn't exist in the food supply. Its normal purpose is that every time that you use folate to participate in processes outside of methylation, such as DNA synthesis...
2020-02-21
15 min
Mastering Nutrition
How to address edema. | Masterjohn Q&A Files #19
Question: How do I address edema? Edema is basically going to be caused by excess salt retention in the body. The reason is that with the exception of very extreme scenarios, your body is going to tightly regulate the sodium concentration of the water in your body, and sodium draws water. Now, that's not to say that the cause is eating salt. And there are cases where eating salt might remove edema. But generally salt retention of total water volume is going to be a big factor. In hypothyroidism it becomes I believe at least pa...
2019-12-04
03 min
Mastering Nutrition
Concerns about long-term bicarbonate supplementation and other suggestions for raising pH | Masterjohn Q&A Files #07
Concerns about long-term bicarbonate supplementation and other suggestions for raising pH Helen Donnell says, "Your post on urine pH and exercise tolerance was a game-changer for me, but anytime I miss a dose of bicarb, I'm right back to 5. Any long-term concerns with taking bicarb two to three times a day, any suggestions for other ways to get my system pH up?" Well, I will say in my case that I stopped taking the bicarbonate when I figured out that I had a zinc deficiency. So, for people who don't know the backstory here, Google "...
2019-11-18
07 min
Mastering Nutrition
Riboflavin for Strange Unresolved Health Problems | Chris Masterjohn Lite # 153
Got any strange, unresolved health problems? 🤭 High-dose riboflavin might help! MIGHT. 😬 This episode is a shot in the dark, but covers how high-dose riboflavin could help with a lot of mystery issues. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delive...
2019-07-09
08 min
Mastering Nutrition
High-Dose Riboflavin for Migraines | Chris Masterjohn Lite #152
Got migraines? 😣 You may need a LOT of riboflavin! 😮 This episode covers what dose to use, and how to time the dosing. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Messenger version is taught by Chris...
2019-07-04
07 min
Mastering Nutrition
Riboflavin for Iron-Deficiency Anemia | Chris Masterjohn Lite #151
Got anemia? 🙋🏽🙋🏼🙋♀️🙋🏿♀️ You may need more riboflavin! 😮 This episode covers how to know if your iron-deficiency anemia could be helped by riboflavin, and what to do about it using food and supplements. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Mess...
2019-07-02
07 min
Mastering Nutrition
The Best Blood Test for Riboflavin | Chris Masterjohn Lite #149
This episode covers the best blood test to use for assessing riboflavin status. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Messenger version is taught by Chris Masterbot, my baby bot, is more interactive, and has more jokes an...
2019-06-25
06 min
Mastering Nutrition
How to Get Enough Riboflavin From Food | Chris Masterjohn Lite #148
Here’s how to get RIBOFLAVIN from FOOD. 🍲 😋 This episode covers how to figure out how much you need, and which foods to get it from. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Messenger version is taught...
2019-06-20
10 min
Mastering Nutrition
Exercise and Dieting Make You Need More Riboflavin | Chris Masterjohn Lite #147
Losing weight? Leaning out? Slimming down? 🙋🏽🙋🏼♂️🙋♀️🙋♂️🙋🏿♀️ Hitting the gym? Doing cardio? Gettin’ yo fat-burnin’ on? 🙋🏽🙋🏼♂️🙋♀️🙋♂️🙋🏿♀️ You might need more riboflavin. 😬 This episode covers by how much, and how to get it from food. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Messenger version is taught by Chris Masterbot, my b...
2019-06-18
07 min
Mastering Nutrition
High-Fat Diets Make You Need More Riboflavin | Chris Masterjohn Lite #146
Eating keto? Low-carb? High-fat? 🙋🏽🙋🏼♂️🙋♀️🙋♂️🙋🏿♀️ You might need more riboflavin. 😬 This episode covers how much more you’d need and how to get it from food. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Messenger version is taught by Chris Masterbot, my baby bot, is m...
2019-06-13
06 min
Mastering Nutrition
Riboflavin and Tanning Beds for Fungal Infections? | Chris Masterjohn Lite #145
Have a fungal infection? Here’s how the combination of tanning beds and riboflavin might help. This is speculative, but worth trying for many people. Make sure to talk to your doctor about any infections you have and anything you’re doing to treat them. Tune in for the details! This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you sh...
2019-06-11
09 min
Mastering Nutrition
Sunlight and Tanning Beds Hurt Your Riboflavin Status | Chris Masterjohn Lite #144
Do you sunbathe or use tanning beds? If so, you might need more riboflavin. Tune in for the details. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Messenger version is taught by Chris Masterbot, my baby bo...
2019-06-06
06 min
Mastering Nutrition
How to Know If You Need More Riboflavin | Chris Masterjohn Lite #143
Riboflavin is the ultimate fat-burning nutrient. 🔥 Could you need more of it? This episode covers the signs you could need a just a little more, and what it would look like if you started running real low. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get i...
2019-06-04
07 min
Mastering Nutrition
How to Take Niacin Without Hurting Your Liver | Chris Masterjohn Lite #142
Niacin is great! BUT… It can hurt your liver. 😟 This episode covers a protocol to make sure niacin doesn’t hurt your liver. It covers the specific form you take, your health history, the dose, and what to take it with to protect your liver. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for speci...
2019-05-30
09 min
Mastering Nutrition
How to Take Niacin Without Flushing | Chris Masterjohn Lite #141
Ugh, the NIACIN FLUSH! 🥵🥵🥵 This episode covers what to do and what NOT to do to avoid it. It covers slow-release niacin, extended-release niacin, inositol hexanicotinate, niacinamide, aspirin, and waiting it out. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger o...
2019-05-28
06 min
Mastering Nutrition
How to Take Niacin Without Getting Diabetes | Chris Masterjohn Lite #140
Here’s how to take NIACIN 😁… without getting DIABETES. 😔 Alex Leaf and I did a HUGE podcast on niacin, and Alex looked at the data on whether it is safe and effective to use for preventing heart disease. Based on that data, one out of every 18 people who use it for this purpose get saved from heart disease, but for every 7 people saved from heart disease, 3 get diabetes. In this episode I cover Alex’s idea on how to take niacin without getting diabetes. This episode is brought to you by Vitamins and...
2019-05-23
10 min
Mastering Nutrition
Should You Use Niacin to Lower Your Blood Lipids? | Chris Masterjohn Lite #139
Should you use niacin to lower your blood lipids? For every seven people that this saves from heart disease, three get diabetes. This episode covers alternative strategies to achieve the same effect of niacin on blood lipids without the risk of diabetes. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or...
2019-05-21
10 min
Mastering Nutrition
The Best Blood Test for Niacin | Chris Masterjohn Lite #138
Here’s why the best test for niacin status is HDRI’s NADH/NADPH, how to use it to calculate the niacin number, and what numbers you should be aiming for. This episode is brought to you by Vitamins and Minerals 101. This is my new, free, 30-day course that covers the basics of each nutrient, including why it’s important, how to get it from food, how to know if you need more, when you should think about supplementing, and concerns for special diets or special populations. You can get it delivered by Facebook Messenger or email. The Me...
2019-05-16
08 min
Mastering Nutrition
How to Get Enough Niacin From Food | Chris Masterjohn Lite #137
Here’s how to get NIACIN from FOOD. 🍲😋 I recommend getting a half gram to a gram of protein per pound of bodyweight (double this if you measure your weight in kilograms), which contributes to your niacin status, as well as 20 milligrams of preformed niacin from food per day. So, here are your foods, arranged in five tiers. Tier 1 supplies close to 15 mg or more per serving. Fresh yellowfin or shipjack tuna, anchovies, liver (beef, lamb, pork), unfortified nutritional yeast in the amount of 3 heaping tbsp. Tier 2 supplies 7-14 mg per s...
2019-05-14
11 min
Mastering Nutrition
Do Women Need More Niacin Than Men? | Chris Masterjohn Lite #136
Do women need more niacin than men? The RDA says they need less. But the evidence suggests otherwise. This episode is brought to you by Ancestral Supplements' Grass Fed Beef Brain. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, bone marrow and brain... all in the convenience of a capsule. For more information or to buy any of their products, go to https://AncestralSupplements.com This...
2019-05-09
09 min
Mastering Nutrition
How to Free the Niacin in Grains and Seeds | Chris Masterjohn Lite #135
Are your whole grains and seeds good sources of niacin? That depends on you prepare them! Whole grains have 80-90% of their niacin locked up, and seeds have 40% of their niacin locked up. This episode covers how to free the bound niacin. This episode is brought to you by Ancestral Supplements' Grass Fed Beef Brain. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, bone marrow and brain... all...
2019-05-07
08 min
Mastering Nutrition
Coffee! How to Free the Locked-Up Niacin | Chris Masterjohn Lite #134
COFFEE 😍😍😍 Is it a good source of NIACIN? That depends on how you brew it. This episode has the details on the effect of roasting, coffee strength, and decaffeination. This episode is brought to you by Ancestral Supplements' Grass Fed Beef Brain. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, bone marrow and brain... all in the convenience of a capsule. For more information or to buy any o...
2019-05-02
06 min
Mastering Nutrition
How to Know If You Need More Niacin | Chris Masterjohn Lite #133
Ever wonder if you need more niacin? This episode covers the signs and symptoms of niacin deficiency as well as the reasons you’d be likely to become deficient. This episode is brought to you by Ancestral Supplements' Grass Fed Beef Brain. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, bone marrow and brain... all in the convenience of a capsule. For more information or to buy any of...
2019-04-30
08 min
Mastering Nutrition
What to Do About Fatty Liver | Chris Masterjohn Lite #129
An estimated 70 million Americans have fatty liver disease, and the strongest predictors are obesity and type 1 or type 2 diabetes. The lab I worked in when I completed my PhD specialized in fatty liver disease, so I did a lot of research on this and have published some papers on it. Here’s my recommended fix, which I call the “choline-boosting modified fast.” It focuses on weight loss that is as rapid as the person can handle, but no more rapid; using the foods least likely to contribute to liver fat, modified according to the person’s abilit...
2019-04-16
10 min
Mastering Nutrition
Ten Steps to Healthy Sleep | Chris Masterjohn Lite #120
Here are ten steps to healthy sleep! What has been most game-changing for you? Let me know in the comments! This episode is brought to you by Ancestral Supplements' Grass Fed Beef Brain. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, bone marrow and brain... all in the convenience of a capsule. For more information or to buy any of their products, go to https://AncestralSupplements.com
2019-03-14
12 min
Mastering Nutrition
How to Make Your Own Melatonin | Chris Masterjohn Lite #117
Here’s how to make your own melatonin. No, not in your basement -- in your brain. We cover the effect of protein, carbs, vitamins, blue-blocking, and sunshine. Tune in for the details! This episode is brought to you by Ancestral Supplements' Grass Fed Beef Brain. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, bone marrow and brain... all in the convenience of a capsule. For mo...
2019-03-05
07 min
Mastering Nutrition
How to Get GABA from Food | Chris Masterjohn Lite | Chris Masterjohn Lite #110
GABA helps relax you, helps you make faster and better decisions under pressure, and helps you face your fears with less of a harmful stress response. Tune in to find out how to get it from FOOD! This episode is brought to you by Ancestral Supplements' "Living" Collagen. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, "living" collagen, bone marrow and more... in the convenience of a capsule...
2019-02-07
05 min
Mastering Nutrition
Introducing the CMJ Masterpass
The CMJ Masterpass is for those of you who really love me. 💙 The GINORMOUS earlybird discount is about to disappear! ⏰So check this out now if you're not a member yet to see if it's for you. (or sign up at https://chrismasterjohnphd.com/masterpass Here's a video tour of what it looks like inside the Masterpass. 🔷The Masterpass is an all-access pass to premium features on all my audio and video content including Chris Masterjohn Lite (short, practical tips), Mastering Nutrition (long, in-depth podcasts on a specific topic), or Masterclass With Masterjohn (nutritional...
2019-01-30
07 min
Mastering Nutrition
Weston Price and Beyond | Mastering Nutrition #52
In this episode, Hilda Librada Gore of the Wise Traditions podcast interviews me about the work of Weston Price, dental researcher extraordinaire and pioneer of nutritional anthropology. In the second half, we talk about how to condense what we've learned since Price's time about nutrition into some practical rules of thumb that can help us achieve the best diet to meet our nutritional needs. It originally appeared on the Wise Traditions podcast as episode 155 and 156. If you can be in Baltimore, MD this weekend, November 16-November 19, come to the Wise Traditions Conference! I'll be giving...
2018-11-14
1h 20
Mastering Nutrition
Why I Don’t Believe in “Overmethylators” and “Undermethylators” | Chris Masterjohn Lite #74
Are you an undermethylator or an overmethylator? Neither! Chris Masterjohn Lite is a show about what works. Today we kick off a short series on a few things that don’t work by discussing why I don’t think it’s useful and why I think it’s actually counter-productive to classify people as undermethylators and overmethylators. This episode is brought to you by Ancestral Supplements. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-t...
2018-10-04
06 min
Mastering Nutrition
Why You Need Glycine: A Panel Discussion | Mastering Nutrition #49
Glycine can you sleep, stabilize your blood sugar, improve your joint health, keep your skin beautiful, and do much more. It's a little amino acid with a big impact on your health. This episode is a panel discussion between Dr. Chris Masterjohn, Alex Leaf of Examine.Com, and Vladimir Heiskanen, covering everything you need to know about glycine. The best way to get glycine is from hydrolyzed collagen. Great Lakes offers the best balance of quality, transparency, and price. Vital Proteins, while more expensive, uses enzymatic digestions rather than heat to hydrolyze the collagen, and...
2018-01-08
1h 50
Mastering Nutrition
Introducing... Testing Nutritional Status: The ULTIMATE Cheat Sheet!
Happy 2018! After many dozens of hours putting this together, I'm super excited to announce "Testing Nutritional Status: The Ultimate Cheat Sheet." Over the course of 2017, many of you followed my podcast series on measuring and managing nutritional status. Some of you absolutely loved it. Some of you found it too technical to follow, or found the episodes too long and dense to share with your friends and family and were excited when I started condensing them into much shorter Chris Masterjohn Lite episodes. At the end of the day, I still am only about 5% through...
2018-01-02
17 min
Mastering Nutrition
I'm Now Accepting New Clients!
Are you interested in working with me one-on-one so I can help you better meet your health goals? Good news! I’m now accepting new clients for both hourly consultations and health and wellness packages. Here are the core things I’m best at that I would love to do for you: Help you develop actionable priorities and an overall strategy for improving your health. Discuss your experiences with you and suggest useful tests that you could ask your doctor about. Analyze the results of genetic tests, digital food logs, and blood and urine measure...
2017-09-01
06 min
Mastering Nutrition
Supercharge Your Folate With Pastured Egg Yolks and Sprouted Legumes | Chris Masterjohn Lite CML #23
The effect of sprouting on the folate concentration of legumes is incredible. It peaks on the fourth day of sprouting, though, according to a recent study. But is it always the fourth day in every legume under any condition sprouted in a home kitchen? Are the sprouted legumes on the store shelf four-day sprouts? Right now there are more questions than answers, but I believe that opting for sprouted legumes is a good way to supercharge your folate status as long as you still make an effort to get 2-3 servings of folate-rich foods per day. I cover t...
2017-04-28
06 min
Mastering Nutrition
019: You Asked Me Anything About Health, Fitness, and Nutrition, Facebook Live, 07/12/16
This episode is a recording of the Facebook Live event, "Ask Chris Masterjohn, PhD, Anything About Health, Fitness, and Nutrition" that originally aired on Tuesday, July 12, at 5:00 PM eastern time. In this episode you will find all of the following and more: For a woman with bruising, spider veins, and cellulite, should we be thinking of collagen, clotting, or calcification? Should we be thinking of vitamin C, copper, glycine, and vitamin K2? Are there nutritional cures for autoimmune diseases? Does eating fruit with protein hurt the digestion and absorption of the protein? Is the Randle cycle...
2016-07-18
1h 34
Mastering Nutrition
018: You Asked Me Anything About Fat-Soluble Vitamins, Facebook Live, 06/29/16
This episode is a recording of the Facebook Live event, "Ask Chris Masterjohn, PhD, Anything About Fat-Soluble Vitamins" that originally aired on Wednesday, June 29, at 5:00 PM eastern time. In this episode you will find all of the following and more: Fat-soluble vitamin nutrition during warfarin therapy, and the critical importance of working with the supervising cardiologist or whoever prescribed the warfarin. Overuse of vitamin D supplements, and the use of parathyroid hormone (PTH), diet, and lifestyle analysis for a more prudent approach. My opinion on Life Extension's vitamin K supplement.
2016-07-02
1h 35
Mastering Nutrition
017: You Asked Me Anything About Methylation, Facebook Live, 06/25/16
This episode is a recording of the 06/25/2016 Facebook Live event, "Ask Chris Masterjohn, PhD, Anything About Methylation." Among the questions answered and topics discussed in this episode are the following: An MTHFR mutation (e.g. C677T) even with normal homocysteine could mean that you are taxing your choline supply and wasting glycine into your urine. Boosting choline and glycine intake could help. What may surprise you is that so could supplementing with creatine! How to implement the above strategies with natural foods? Can targeted SAMe supplementation be useful for diagnosing...
2016-06-28
1h 38
Mastering Nutrition
Dietary Management of Heterozygous Familial Hypercholesterolemia (HeFH) | Mastering Nutrition #14
In this episode, I discuss dietary management of familial hypercholesterolemia (HeFH). This question was asked on the Facebook Live episode from 06/16/2016, "Ask Chris Masterjohn, PhD Anything About Heart Disease," but I was unable to get to the question within Facebook's time limit. Please note that HeFH is a medical issue and the purpose of this episode is not to diagnose or treat anyone with HeFH. This is educational in nature and the information should only be used to manage HeFH under supervision of a qualified health professional. Herein, I discuss why I believe the Kitavan...
2016-06-23
44 min
Mastering Nutrition
015: You Asked Me Anything About Heart Disease, Facebook Live 06/16/2016
This episode is a recording of the 06/16/2016 Facebook Live event, "Ask Chris Masterjohn, PhD Anything About Heart Disease." Among the questions answered in this episode are the following: Should we be micromanaging specific saturated fatty acids to prevent heart disease? Should we use our knowledge of our ApoE genotype to help decide what to eat (and specifically, should the E4 allele causes us to avoid saturated fat)? The persistent importance of the total-to-HDL-cholesterol ratio. Why the vitamin E content of HDL particles could be determining its protective functions.
2016-06-20
1h 28