Shows
Kardio-Know-HowEp.256. ACC 2026 - część 3. Dziesięć strategii postępowania w migotaniu przedsionków - DOAC vs zamykamy uszko.Witam Państwa, nazywam się Jarosław Drożdż, pracuję w Centralnym Szpitalu Klinicznym Uniwersytetu Medycznego w Łodzi, skąd nagrywam podcast Kardio Know-How. W tym odcinku omawiam drugą część badań opublikowanych podczas kongresu ACC 2026. Do gabinetu trafia typowy pacjent z migotaniem przedsionków (75 lat, CHA₂DS₂-VASc 3, wielochorobowość, brak przeciwwskazań do DOAC), a dylemat dotyczy wyboru między leczeniem przeciwzakrzepowym a zamknięciem uszka lewego przedsionka (LAA). Najnowsze badania i opinie ekspertów są podzielone: Kim Eagle dopuszcza implantację zamiast DOAC, natomiast John Mandrola krytykuje procedurę i wskazuje na brak wystarczających dowodów z randomizowanych badań. Autor podkreśla jednak...
2026-04-2416 min
The Diary Of A CEO with Steven BartlettStanford Neuroscientist: Can’t Remember Your Dreams? Your Brain May Be Warning You!Most people think they’re a single individual making rational decisions, but Stanford Neuroscientist, Dr. David Eagleman, explains that you are actually multiple people in one brain. A brain that tricks each version of you in different ways!Dr. David Eagleman is a Stanford neuroscientist, technologist, and author who examines how our brain interprets the world and what that means for us. He is known for his work on brain plasticity, perception, and how the brain adapts to external inputs. He is the cofounder of Neosensory and BrainCheck, as well as director of the Center for Science an...
2026-04-231h 33
The Diary Of A CEO with Steven BartlettThe Peptide Expert: Big Pharma Are Hiding This Powerful Peptide From You! - Dr. Alex TatemThe FDA silently banned 19 peptides overnight, now RFK Jr is reversing it all. Dr Alex Tatem reveals the truth behind the cover-up, and what peptides can really do for your body.Dr. Alex Tatem is an internationally recognised urologist who has studied peptides for 12 years and runs a men’s health clinic. He also hosts a YouTube channel dedicated to demystifying peptides and men's health.In this explains:◼ What peptides are, how they work, and which ones target your health problem◼Why the peptide industry is quie...
2026-04-201h 29Kardio-Know-HowEp.255. ACC 2026 - część 2. CHAMPION-AF, CLOSURE-AF: Twój pacjent ma migotanie przedsionków - DOAC czy zamykamy uszko?Witam Państwa, nazywam się Jarosław Drożdż, pracuję w Centralnym Szpitalu Klinicznym Uniwersytetu Medycznego w Łodzi, skąd nagrywam podcast Kardio Know-How. W tym odcinku omawiam drugą część badań opublikowanych podczas kongresu ACC 2026. Migotanie przedsionków będzie narastać wraz z epidemią otyłości, ponieważ dzieli z nią wspólny szlak patofizjologiczny prowadzący także do HFpEF, dlatego kluczowe znaczenie ma leczenie przyczynowe (upstream therapy), a nie rutynowa kardiowersja. W badaniu CLOSURE-AF porównującym DOAC z zamknięciem uszka lewego przedsionka (LAA) u pacjentów wysokiego ryzyka uzyskano podobną liczbę udarów i krwawień, ale więcej zgonów w g...
2026-04-1719 min
AI Unraveled: Latest AI News, ChatGPT, Gemini, Claude, DeepSeek, Gen AI, LLMs, Agents, Ethics, Bias[SPECIAL SINGULARITY] 🧪 Deconstructing David Sinclair on DOAC: Can Aging Be Reversed? Epigenetic Reprogramming and the Longevity Mythos (April 05th 2026)🎧 Listen Ads-Free: Tired of interruptions? Subscribe to AI Unraveled directly on Apple Podcasts at https://podcasts.apple.com/us/podcast/djamgamind-executive-intelligence-the-technology/id1864721054Summary: In this Special Edition, we take a forensic magnifying glass to Dr. David Sinclair's explosive interview on the Diary of a CEO (DOAC) podcast. Sinclair claims that aging is merely a loss of "epigenetic information"—a software glitch that can be rebooted—and cites studies where cells appear 75% younger in just 8 weeks. We use DeepResearch to cross-reference these claims with actual, peer-reviewed bio-gerontology. We separate the breathtaking reality of Yamanaka factors and cellular reprogramming from th...
2026-04-1253 min
The Diary Of A CEO with Steven BartlettIvanka Trump: My Dad Told Me Two Weeks Before He Ran For President!She built an $800 million business…but sacrificed it all when her father became President, now Ivanka Trump tells her story!Ivanka Trump is a world-renowned businesswoman, real estate developer, and entrepreneur who served as Advisor to the President during Trump’s first administration. She was previously Executive Vice President in the Trump Organization, and is the author of 2 New York Times bestsellers, including ‘Women Who Work: Rewriting the Rules for Success’.She explains:▪️The negotiation tactic used to close billion-dollar deals▪️Why she permanently stepped back from the Trump campaign
2026-04-091h 35
CLOT ConversationsWhich DOAC Bleeds Less? COBRRA Trial Insights for VTE Care with Dr Lana CastellucciSend us Fan MailWhich DOAC bleeds less in acute VTE?In this episode, we explore the COBRRA trial comparing apixaban vs rivaroxaban and what it means for clinical practice.The COBRRA trial provides the first direct, randomized comparison of apixaban and rivaroxaban for the treatment of acute venous thromboembolism (VTE).In this episode of CLOT Conversations, Dr. Lana Castellucci discusses findings from this landmark study and how they should influence anticoagulant selection.Key insights include:Apixaban reduced clinically relevant bleeding by more than 50% compared to...
2026-04-0616 min
AI Unraveled: The Daily Pulse (2-Minute Briefings - MULTILINGUAL)[SPECIAL SINGULARITY TEASER] 🧪 Deconstructing David Sinclair on DOAC: Can Aging Be Reversed? Epigenetic Reprogramming and the Longevity Mythos (April 05th 2026)🎧 Listen Ads-Free: Tired of interruptions? Subscribe to AI Unraveled directly on Apple Podcasts at https://podcasts.apple.com/us/podcast/djamgamind-executive-intelligence-the-technology/id1864721054Summary: In this Special Edition, we take a forensic magnifying glass to Dr. David Sinclair's explosive interview on the Diary of a CEO (DOAC) podcast. Sinclair claims that aging is merely a loss of "epigenetic information"—a software glitch that can be rebooted—and cites studies where cells appear 75% younger in just 8 weeks. We use DeepResearch to cross-reference these claims with actual, peer-reviewed bio-gerontology. We separate the breathtaking reality of Yamanaka factors and cellular reprogramming from th...
2026-04-0501 min
The Diary Of A CEO with Steven BartlettAnti-Aging Expert: Stop Touching Receipts Immediately! The Fast Way To Shrink Visceral FatFat is destroying your organs! The Longevity Scientist Dr Rhonda Patrick explains what actually burns it.Dr. Rhonda Patrick is a Ph.D. biomedical scientist specialising in ageing, nutrition, and disease prevention. She is the founder of FoundMyFitness, a popular YouTube channel and podcast dedicated to translating complex health science into actionable advice.She explains:◼ Why visceral fat acts like a toxic organ that doubles your risk of early death◼ How 2 weeks of poor sleep increased visceral fat by 11% without gaining a pound◼ The 3 chemic...
2026-03-302h 39
The Diary Of A CEO with Steven BartlettDavid Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!Scientist and Harvard professor Dr. David Sinclair, A.O., Ph.D., reveals his latest research on how to reverse ageing, insights into vitamins and supplements, why DNA is not your destiny, and the first clinical trials to reverse human ageing and blindness!Dr. David Sinclair is a world-renowned Professor of Genetics at Harvard Medical School and the leading authority on longevity science. He is Founder of Lifespan.com and multiple biotechnology companies, Co-Chief Editor of the journal Ageing, and bestselling author of ‘Lifespan: Why We Age - And Why We Don’t Have To’.
2026-03-232h 29
What's it Worth? A Journal Club PodcastS4E2 - The Kidney Formula Conundrum: Navigating eCrCl vs. eGFR in DOAC Dosing Welcome back to What's it Worth! Join your hosts, Dr. Diana Langworthy and guest Dr. Rachel Khan (Associate Professor at VCU School of Pharmacy), as they navigate the murky waters of renal function assessment in anticoagulant users. This episode dissects a critical insight from the ORBIT-AF II registry: the variability in DOAC (NOAC) dose eligibility when labs use newer kidney estimates . While clinical trials used Cockcroft-Gault (eCrCl), modern labs often report eGFR (MDRD or CKD-EPI), leading to a "renal identity crisis" for clinicians . We're putting on our EBP detective hats to explore why these formulas disagree—and what that me...
2026-03-2051 min
The Diary Of A CEO with Steven BartlettThe Iran War Expert: I Simulated The Iran War for 20 Years. Here’s What Happens NextWhite House war advisor ROBERT PAPE reveals why Trump is trapped in a war with Iran, the risk of a nuclear breakout, the role of China in the conflict, and how the US is losing control of the Middle East.Robert Pape is a renowned political scientist and director of the Chicago Project on Security and Threats. He has advised every White House since 9/11 on military strategy and is the author of Bombing to Win: Air Power and Coercion in War.He explains:▪️The 3 stages of t...
2026-03-121h 29
The Diary Of A CEO with Steven BartlettNo.1 Christianity Expert: The Truth About Christianity! The Case For Jesus (Historian's Proof)Bible sales are soaring. Christian Faith Defender Wesley Huff on why the West is rediscovering Jesus.Wesley Huff is a PhD candidate and leading Christian apologist specialising in the historical accuracy of ancient Biblical texts. He serves as the Director of Central Canada for Apologetics Canada and is the host of a YouTube channel dedicated to the science of faith.He explains:▪️Why Christianity and interest in the Bible are rising again▪️Why New Atheism may have left a generation in a meaning crisis▪️How to think abo...
2026-03-092h 26
The Diary Of A CEO with Steven BartlettTop CIA Security Advisor: Jeffrey Epstein Epstein Was A Made Up Person & They Can See Your Messages!World-renowned security expert Gavin de Becker reveals how governments read your messages, why Jeffrey Epstein was a construct, secrets from White House and CIA protection, and how to trust your gut and stay safe in a digital world!Gavin de Becker is a security and violence prevention expert with over 50 years of experience, and founder of Gavin de Becker & Associates. He is widely considered to be the leading expert on anti-assassination strategies, and is a best-selling author whose books on the prevention of violence are published in 30-language.He explains:◼️How to use...
2026-03-011h 44
The Diary Of A CEO with Steven BartlettPregnancy Diet Expert: The Pregnancy Diet That Rewrites DNA! Why Pregnant Moms Are Being Lied To!Glucose Goddess Jessie Inchauspé exposes the pregnancy diet rewriting your baby’s DNA, how sugar in pregnancy spikes insulin, and the simple protein and supplement fixes most mothers miss!Jessie Inchauspé is a world-renowned biochemist and founder of the Glucose Goddess movement. She is the international bestselling author of books such as ‘The Glucose Goddess Method, and her latest book is ‘9 Months That Count Forever’.She explains:◼️How glucose spikes in the womb program a baby’s future diabetes risk◼️The 4 specific hacks to reduce blood sugar spikes by up to 75%◼️Why eating 28 eggs a week is...
2026-02-261h 36
The Diary Of A CEO with Steven BartlettUber CEO: At Uber, If You Don’t Perform, You’re Out! Uber Was Losing $3b A YearUber CEO Dara Khosrowshahi reveals the future of driverless cars, how he led Uber’s financial turnaround, his family’s escape from Iran in 1978, and the truth about AI, automation, and job loss!Dara Khosrowshahi is the CEO of Uber and successfully transformed the company from losing $3 billion a year to generating over $9 billion in free cash flow. He previously served as CEO of Expedia for over a decade, scaling the company into a global leader in online travel. He explains: ◼️The "wartime" leadership strategy he used to save Uber from...
2026-02-231h 43
The Diary Of A CEO with Steven BartlettThe Greatest Climber Alive: I Shouldn't Have Attempted That Climb!The man who risked death climbing 3,000ft up El Capitan, Alex Honnold, reveals how to master extreme pressure, why his brain scan showed zero fear, the science of risk, and his visualisation secrets. Alex Honnold is a professional rock climber and the first person to free solo El Capitan and Taipei 101, the 11th tallest building in the world. He is also the bestselling author of the book, ‘Alone on the Wall: Alex Honnold and the Ultimate Limits of Adventure’ and founder of the Honnold Foundation. He explains:◼️How to rewire your...
2026-02-191h 37
Zkouška po kmeni VPL: Opakování krok za krokem (α)-75 mini dialogů.65. Kmen VPL(α): Antikoagulace. Warfarin versus DOAC – 🩺 Diagnostika a terapie🩸 ⚖️ 💊 Antikoagulace: Warfarin versus DOAC (ZK VPL č. 65: Antikoagulační léčba)Vítejte u podcastu Zkouška po kmeni VPL: Opakování krok za krokem. V této epizodě probereme ředění krve. Správně nastavená antikoagulace chrání před mrtvicí, špatná může zabít krvácením.🎧 Co se v této epizodě naučíte: ✅ Indikace: Fibrilace síní (prevence CMP) a Tromboembolická nemoc (léčba HŽT/PE). ✅ Warfarin: Monitorace INR (cíl 2-3), interakce s jídlem a léky. Kdy je stále lékem volby (umělé chlopně!). ✅ DOAC (NOAC): Výhody (bez monitorace, méně krvácení) a dávkování dle ren...
2026-02-1617 min
The Diary Of A CEO with Steven BartlettCognitive Decline Expert: The Disease That Starts in Your 30s but Kills You in Your 70sAlzheimer’s expert LOUISA NICOLA explains early Alzheimer’s risk, why creatine fuels brain energy and memory, deep sleep hacks, and why sitting is a silent killer!Louisa Nicola is a leading neurophysiologist and human performance coach who studies the brain and nervous system. She is the founder of Neuro Athletics, a consulting firm that provides scientific strategies for cognitive performance, and is also currently finishing her PhD at the University of Washington. She explains:▪️Why 70% of Alzheimer's patients are women▪️The "leaky brain" warning signs you are ignoring
2026-02-052h 05
The Diary Of A CEO with Steven BartlettDopamine Expert: Short Form Videos Are Frying Your Brain! This Is A Dopamine Disaster!Dopamine expert DR ANNA LEMBKE reveals how addiction is hijacking your brain, why dopamine addiction is rising fast, the danger of social media, porn, AI, GLP-1 drugs, and how to regain control FAST!Dr Anna Lembke is Professor of Psychiatry and Medical Director of Addiction Medicine at Stanford University School of Medicine. She has spent over 25 years treating patients with substance and behavioral addictions and is the bestselling author of “Dopamine Nation”. She explains:◼️Why endless pleasure quietly trains your brain to feel worse, not better◼️How digital habits replace real...
2026-01-051h 46
The Diary Of A CEO with Steven BartlettThis Is The Fastest Way To Get Dementia...The 6 Science-Backed Brain Fixes!New year, healthier brain? Start 2026 RIGHT by protecting your brain, with EXPERT advice from The Diary Of A CEO’s top guests on brain health, dementia risk, brain fog, nutrition, addiction, and more! This EXCLUSIVE CHRISTMAS EPISODE brings together BRAIN HEALTH advice from world-leading experts, including: ◼️Dr Rhonda Patrick ◼️Dr Wendy Suzuki ◼️Andrew Huberman ◼️Dr Nathan Bryan ◼️Dr Daniel Amen ◼️Simon MillsThey explain: ◼️Why dementia and Alzheimer’s often begin with damaged blood flow, not memory loss◼️How food, nitric oxide, and circulation directly affect brain a...
2025-12-261h 05Kardio-Know-HowEp.238 AHA 2025 - część 3. Czy można łączyć DOAC z ASA? OPTIMA-AF, ADAPT AF, AQUATICWitam Państwa, nazywam się Jarosław Drożdż, pracuję w Centralnym Szpitalu Klinicznym Uniwersytetu Medycznego w Łodzi, skąd nagrywam podcast Kardio Know-How. W tym odcinku rozpoczynam kontynuuję omawianie doniesień z tegorocznego kongresu AHA.Pacjent z migotaniem przedsionków po przezskórnej rewaskularyzacji często wymaga połączenia DOAC z terapią przeciwpłytkową i w wielu przypadkach jest to rozwiązanie nie tylko dopuszczalne, lecz konieczne. W terapii potrójnej – DOAC, ASA i inhibitor P2Y12 – jedynym rekomendowanym inhibitorem P2Y12 jest klopidogrel, ponieważ ticagrelor i prasugrel znacząco zwiększają ryzyko krwawień, co potwierdzają zarówno wytyczne ESC 2023, jak i da...
2025-12-0516 min
The Diary Of A CEO with Steven BartlettAI Expert: We Have 2 Years Before Everything Changes! We Need To Start Protesting! - Tristan HarrisEx-Google Insider and AI Expert TRISTAN HARRIS reveals how ChatGPT, China, and Elon Musk are racing to build uncontrollable AI, and warns it will blackmail humans, hack democracy, and threaten jobs…by 2027Tristan Harris is a former Google design ethicist and leading voice from Netflix’s The Social Dilemma. He is also co-founder of the Center for Humane Technology, where he advises policymakers, tech leaders, and the public on the risks of AI, algorithmic manipulation, and the global race toward AGI.Please consider sharing this episode widely. Using this link to share the episode will earn...
2025-11-272h 22
The Diary Of A CEO with Steven BartlettNo.1 Brain Scientist: Your Brain Is Lying To You! Here's How I Discovered The Truth!Harvard Neuroscientist DR. JILL BOLTE TAYLOR reveals How to Retrain Your Brain, Heal Trauma, Control Emotions, and Unlock the 4 Characters Running Your MindDr. Jill Bolte Taylor is a Harvard-trained brain scientist who experienced a stroke in the left hemisphere of her brain and spent 8 years recovering. She is best known for her viral TED Talk “My Stroke of Insight” and is the bestselling author of books including Whole Brain Living.She explains:◼️What her near-death stroke taught her about consciousness, ego, and identity◼️How to escape the brain loop keeping you stuck in...
2025-11-061h 36
The Diary Of A CEO with Steven BartlettNo. 1 Sugar Expert: 17 Seconds Of Pleasure Can Rewire Your Brain!Dr. Robert Lustig, a world-leading expert on sugar addiction, metabolism, ultra-processed food, and artificial sweeteners, reveals how they fuel obesity, dementia, dopamine overload, and addiction - and the dangers of RFK Jr.’s health approach.Dr. Robert Lustig is a neuroendocrinologist and expert on sugar, obesity, and the science of addiction, whose groundbreaking new research reveals how the 4 major health crises are all interconnected and driven by stress. He is also the bestselling author of books such as, ‘Metabolical’, and ‘Fat Chance’. He explains:◼️Why 29% of Americans are depressed and how food pl...
2025-10-021h 50
IPSA PodcastVragen die blijven knagen: Optimale zorg bij DOAC'sElke aflevering hebben we bij IPSA vzw de eer om een interessante gastspreker uit te nodigen om de vragen die blijven knagen na de IPSA lessen voor te leggen. Tijdens deze aflevering gaan we dieper in op vragen die blijven knagen na de les 'Optimale zorg bij DOAC's'. Daarvoor hebben we doctor en ziekenhuisapotheker Andreas Capiau uitgenodigd om hem aan een vragenvuur te onderwerpen over de DOAC's.(00:00) - Indicaties en therapietrouw
(11:00) - Gebruiksinstructies
(16:00) - Ongewenste effecten
(24:04) - Interacties
(29:36) - Slot
2025-09-2932 min
The Diary Of A CEO with Steven BartlettAtheist vs Christian vs Spiritual Thinker: The Paperclip Problem That Exposes Religion!Are We Living Through the BIGGEST Crisis of Purpose & Meaning in History?3 in 5 young Americans believe that their life lacks purpose. This isn’t just a statistic, it’s a silent epidemic reshaping mental health, identity and future...So, how do we fix it?In this DOAC debate, Greg Koukl (Christian), Alex O’Connor (atheist), and Dr K (psychiatrist) explore why so many feel lost, whether God is the answer, how death anxiety drives our search for meaning, and how YOU can find direction…today. This isn’t just a discussion...
2025-09-293h 21
The Curbsiders Internal Medicine Podcast#499 Inpatient DOAC Dilemmas with Dr. Jori MaySorting out DOAC Drama in the Hospital
Is it treatment failure or not? Join us for a great conversation with Dr. Jori May (University of Alabama-Birmingham) on all the nuances around DOAC treatment failure and treatment indications for the hospitalized patient.
Claim CME for this episode at curbsiders.vcuhealth.org!
Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME
Show Segments
Intro
Rapid fire questions/Picks of the Week
Case 1
Definitions
Missed Doses
Lab Monitoring
Medical Conditions impacting DOACs
Imaging
D-dimer Usefulness
Treatment Switching
Case 2
LV Thrombus
Reversibility
Outro
Credit...
2025-09-221h 07The Curbsiders Internal Medicine Podcast#499 Inpatient DOAC Dilemmas with Dr. Jori MaySorting out DOAC Drama in the Hospital
Is it treatment failure or not? Join us for a great conversation with Dr. Jori May (University of Alabama-Birmingham) on all the nuances around DOAC treatment failure and treatment indications for the hospitalized patient.
Claim CME for this episode at curbsiders.vcuhealth.org!
Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME
Show Segments
Intro
Rapid fire questions/Picks of the Week
Case 1
Definitions
Missed Doses
Lab Monitoring
Medical Conditions impacting DOACs
Imaging
D-dimer Usefulness
Treatment Switching
Case 2
LV Thrombus
Reversibility
Outro
Credit...
2025-09-221h 07
The Diary Of A CEO with Steven BartlettThe Insulin & Heart Doctor: The Fastest Way To Burn Dangerous Visceral Fat. This is How Insulin Is Quietly Clotting Your Blood! - Dr Pradip JamnadasWhat if EVERYTHING your doctor told you about heart disease is completely WRONG?
World-renowned cardiologist Dr. Pradip Jamnadas drops BOMBSHELLS that will make you question decades of medical advice. With over 35 years of experience and 250,000+ patients saved, he's ready to expose the TRUTH the medical establishment doesn't want you to know, and what you can do to protect your heart, reverse chronic illness, and live longer.
He is an interventional cardiologist and founder of the Heart and Vascular Institute of Central Florida and of Aristotle Education, a prevention clinic focused on fasting, gut health, and...
2025-09-221h 55
The Diary Of A CEO with Steven BartlettMoney Making Experts: This 3-Step 'Offer' Formula Makes $20k Per Month! Alex Hormozi, Codie Sanchez, Daniel PriestleyCould your first $100K be closer than you think? 3 renowned money making experts reveal the exact blueprint for turning $1,000 into $100K, building passive income, hiring A-players, and scaling fast!
This Diary Of A CEO roundtable brings together contrarian investor and private equity dealmaker Codie Sanchez, entrepreneur and investor Alex Hormozi, and serial entrepreneur and business strategist Daniel Priestley.
They discuss:
The exact 3-step offer formula that can generate $20K/month
How to turn any skill into a $10K/month business
Why most entrepreneurs st...
2025-08-072h 33
The Diary Of A CEO with Steven BartlettEric Weinstein (Ex-Harvard Physicist): The Collapse Has Already Started! Jeffrey Epstein Was A Front!Are We Already Living Through Societal Collapse?
Eric Weinstein sounds the alarm on AI threats, corrupt science, drone warfare, nuclear war, and deep-state secrets like Epstein. A world-renowned thinker, he asks: Are Elon Musk and the laws of physics our only escape route?
Eric Weinstein is a mathematician, former Managing Director of Thiel Capital, and one of today’s most provocative intellectuals. He is also the host of the popular podcast ‘The Portal’, where he tackles controversial topics - from the failures of academia to the rise of AI, the limits of physics...
2025-07-142h 31
DR.HAPPY HUMAN PLUMBER 人體水電工🎙️EP143｜不是都一樣抗凝？DOAC 四大藥物比較與臨床選擇指南🎙️EP143｜不是都一樣抗凝？DOAC 四大藥物比較與臨床選擇指南⸻🌟主題亮點： DOAC 是什麼？為什麼逐漸取代華法林？ Apixaban、Rivaroxaban、Edoxaban、Dabigatran 差在哪？ 哪種病人適合哪種藥？腎功能差能用哪一種？ 出血風險、劑量調整與抗凝逆轉劑的最新建議整理⸻🔍內容解析：本集重點：DOAC（Direct Oral Anticoagulants，直接口服抗凝劑）包括四種常見藥物：Apixaban（Eliquis）、Rivaroxaban（Xarelto）、Edoxaban（Lixiana）與Dabigatran（Pradaxa），這些藥物為非瓣膜性心房顫動、靜脈栓塞（VTE）、肺栓塞等疾病提供更穩定、安全的抗凝治療。但它們劑量、代謝途徑、副作用風險與使用族群各有不同。本集我們將完整整理這四種 DOAC 的比較表，並以臨床案例幫助你選擇「對的藥，給對的病人」。👂你將學到： DOAC 四種藥物的作用機轉（Xa 抑制 vs Thrombin 抑制） Apixaban 腎功能安全性較佳？哪種藥一天吃一次 vs 一天兩次？ 哪些病人不適合使用 Dabigatran？逆轉劑有何差異？ 出血風險與 GI tolerance（腸胃耐受）差異比較 用於心房顫動 vs 深層靜脈血栓 vs 肺栓塞的適應症概覽🎯適合收聽對象： 臨床醫師、住院醫師、藥師與護理人員 有心房顫動、VTE、術後栓塞風險的病人與家屬 想深入了解抗凝藥物選擇邏輯的你 醫學生與考研族群需要搞懂 DOAC 差異的你⸻📌熱門關鍵字：#DOAC比較 #Apixaban #Rivaroxaban #Edoxaban #Dabigatran#抗凝劑 #口服抗凝藥 #心房顫動 #VTE治療 #出血風險管理 #PAD #af #動脈阻塞👨⚕️主講人｜Dr. Happy Human Plumber藥物再多也不怕，只要選對抗凝節奏，就能守住血流與生命的平衡。
2025-06-2308 min
The Diary Of A CEO with Steven BartlettThe Sex Expert (Esther Perel): The Relationship Crisis No One Talks About That's Killing Your Sex Life!Swipe left, feel empty, and wonder why? Esther Perel reveals the hidden truths behind the dating crisis, loneliness, and the shocking decline in sex and intimacy.
Esther Perel is a world-renowned psychotherapist and relationship expert, widely recognised as one of today’s most insightful and original voices on modern relationships. She is the bestselling author of books such as, ‘The State of Affairs’.
She explains:
Why MEN Over 30 Aren’t Having Sex Anymore.
The SEX GAME that could Save Your Relationship.
How CHILDHOOD TRAUMA is...
2025-06-121h 29
The Diary Of A CEO with Steven BartlettCEO Diaries: The Brutal Mistake That Almost Crippled Snapchat!In this episode of CEO Diaries, Snapchat CEO Evan Spiegel reveals the biggest hiring mistakes that nearly cost him everything. Overvaluing experience, ignoring culture, and avoiding tough feedback can quietly kill a company, and this brutally honest insight will change how you build teams forever.
Visit - www.linkedin.com/DOAC
Listen to the full episode here -
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Apple - https://g2ul0.app.link/6VjMycy4TTb
2025-06-0415 min
The Diary Of A CEO with Steven BartlettYour Toes Can Predict If You'll Die Early And Heres's How To Fix Your Plantar Fasciitis! - Dr. Courtney Conley (Foot Expert)What if the secret to fixing back pain, avoiding dementia, and living longer is…your feet? Dr. Courtney Conley breaks down why your shoes are failing you.
Dr Courtney Conley is a physician specialising in foot and gait mechanics. She is the founder of ‘Gait Happens’ and ‘Total Health Solutions’, where she aims to educate people about the importance of the human foot to overall health.
She explains:
How foot pain leads to emotional distress, depression, and inactivity
How 500 extra steps a day can cut heart attac...
2025-05-291h 32
The Diary Of A CEO with Steven BartlettCEO Diaries: Airbnb’s Founder Brian Chesky on Brutal Rejection, Great Leadership, and The Biggest Mistake Founders Make!From cold emails to global dominance - the Airbnb story began with rejection. In this unmissable episode of CEO Diaries, Airbnb founder and CEO Brian Chesky reveals the brutal truth about rejection, resilience, building world-changing companies, and the one thing more important than product or profit: culture.
Visit - www.linkedin.com/DOAC
Listen to the full episode here -
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Watch the Episodes On YouTube -
2025-05-2814 min
The Diary Of A CEO with Steven BartlettCEO Diaries: LinkedIn Founder Reid Hoffman: The Truth About Elon, Zuck, & Building Great Companies!Over the next six weeks, we’re bringing you the most unmissable moments from The Diary of a CEO, a masterclass in work, business, and entrepreneurship. These are the lessons that built some of the most iconic companies in the world, shared by the visionary CEOs behind them.
We begin with Reid Hoffman, co-founder of LinkedIn. In this powerful conversation, Reid breaks down the surprising trait that separates good entrepreneurs from the greats and why ignoring it could be your biggest mistake. He shares the story of whats like working with Elon Musk, what mos...
2025-05-2110 min
The Diary Of A CEO with Steven BartlettWe Can Now Reverse Stage 4 Cancer & These Foods Are Spreading It! Dr. William Li (Chronic Disease Expert)Is your daily diet secretly fuelling chronic disease? Dr. William Li reveals the shocking truth about what you're really eating.
Dr. William Li is a world-renowned medical scientist specialising in chronic disease and blood vessel growth. He is Founder & President of the Angiogenesis Foundation, and his groundbreaking research has led to 44 medical treatments that target over 70 diseases. He is also the bestselling author of ‘Eat To Beat Your Diet’.
He explains:
The number one common food that feeds cancer cells
The surprising link between salt and a...
2025-05-192h 07
The Diary Of A CEO with Steven BartlettChris Eubank Jr: I Was Paid $**** For The Fight! The Night Before, My Dad Finally Opened Up!He silenced the critics, defied the odds, and walked through fire - Chris Eubank Jr. tells the full story of one of 2025’s most unforgettable fights.
Chris Eubank Jr. is a world-class professional boxer, middleweight contender, and son of the legendary former professional boxer, Chris Eubank Sr. In April 2025, he won against Connor Benn in one of the most highly anticipated fights in British boxing history.
He discusses:
Why he refused to shake Conor Benn’s hand.
Why the fight almost collapsed the night before.
...
2025-05-081h 49
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast1021: How Long Is the Duration of DOAC Interference With Heparin Anti-Xa Levels?Show notes at pharmacyjoe.com/episode1021. In this episode, I’ll discuss the duration of DOAC interference with heparin anti-Xa levels.
2025-04-2804 minThe Diary Of A CEO with Steven BartlettMasculinity Debate: Are Dating Apps Creating A Generation Of Incels?! Lonely Men Are More Dangerous Than Ever!Are we raising a lost generation of men? Is society failing young boys? In this emergency discussion, Steven sits down with expert guests to explore the recently published ‘Lost Boys Report’.
Scott Galloway is a professor of marketing at NYU Stern School of Business and a member of the advisory council for the American Institute for Boys and Men. Logan Ury is a behavioral scientist turned dating coach and the Director of Relationship Science at Hinge. Together, they bring expertise in culture, psychology, and societal trends to unpack the crisis highlighted in the Lost Boys...
2025-03-312h 26
Last Week in MedicineHalf Dose DOAC for Long Term VTE Prevention, Biomarker Guided Antibiotics for Sepsis, GPT-4 Assistance for Physicians, Optimal Vasopressin Initiation for Shock, DOAC vs No AC for A fib After Intracerebral Hemorrhage, HFNC vs NIV for Respiratory FailureFor this episode we are joined by EBM guru, Dr. Brian Locke, who deftly breaks down all of our statistics questions. Is half dose DOAC as good as full dose DOAC for preventing VTE, and does it reduce bleeding risk? Can procalcitonin reduce duration of antibiotics for infections without compromising mortality rates? Can LLMs like GPT-4 help physicians manage patients better? Can reinforcement learning models predict when to start vasopressin in patients with septic shock? What is the risk of resuming anticoagulation in patients with atrial fibrillation and prior intracerebral hemorrhage? Is high flow nasal cannula as g...
2025-03-271h 32The Diary Of A CEO with Steven BartlettEMERGENCY DEBATE: They Lied About The Economy Recovering! Is A Financial Apocalypse Coming?Is the economy on the brink of collapse? Gary Stevenson and Daniel Priestley break down the emergency financial crisis no one is talking aboutThe Diary Of A CEO’s economics debate is joined by 2 experts: Gary Stevenson and Daniel Priestley. Gary Stevenson is a British economist, former financial trader, and author of The Trading Game. Daniel Priestly is an award-winning serial entrepreneur who has written 5 books on starting and scaling businesses.In this conversation, Gary, Daniel, and Steven discuss topics such as, whether there is a financial apocalypse lo...
2025-03-202h 26
The Diary Of A CEO with Steven BartlettThe Speaking Coach: The One Word All Liars Use! Stop Saying This Word, It's Making You Sound Weak! The More You Do This, The More You Sound Like A Liar!How do you communicate like a top lawyer and command respect? Jefferson Fisher reveals the courtroom-tested tricks that win cases AND everyday conversations Jefferson Fisher is a trial lawyer, communication expert, and host of ‘The Jefferson Fisher Podcast’, where he teaches how to communicate with confidence. He is also the bestselling author of the upcoming book, ‘The Next Conversation: Argue Less, Talk More’. In this conversation, Jefferson and Steven discuss topics such as, how to make people agree with you instantly, the body language tricks that make you sound powerful...
2025-03-172h 18
The Diary Of A CEO with Steven BartlettDr. Joe Dispenza: Secret To Living Without Fear & Anxiety Forever! Your Mind Can Heal Itself! Stress Is The Root Of 90% Of All Diseases!What if 95% of your life is controlled by your subconscious mind? Dr Joe Dispenza reveals how to break free and reprogram your mind for success Dr Joe Dispenza is a researcher, lecturer, and corporate consultant who has developed a practical formula to help people transform their lives. He is also the best-selling author of books such as, ‘Becoming Supernatural: How Common People Are Doing the Uncommon’ and ‘You Are the Placebo: Making Your Mind Matter’. In this conversation, Dr Joe and Steven discuss topics such as, the link between stress and...
2025-03-131h 51
The Diary Of A CEO with Steven BartlettThe Public Speaking Expert: This Speaking Mistake Makes People Ignore You! These Small Mistakes Make You Unlikeable!Speaking with confidence isn’t a gift, it’s a skill - Vinh Giang reveals the blueprint to mastering the art of communicationVinh Giang is an award-winning entrepreneur, part-magician, and full time communication coach. He runs masterclasses and has helped thousands of people improve their communication and vocal skills.In this conversation, Vinh and Steven discuss topics such as, the top speaking mistake that makes people ignore you, small mistakes that make you unlikeable, how to effortlessly speak with power and confidence, and the number one word to avoi...
2025-03-102h 27
The Diary Of A CEO with Steven BartlettThe Ageing Doctor: These Are They Early Signs Of Arthritis! If You Run & Don't Do This, Start Now! The Secret Cause of Alzheimer's!Could you be losing bone strength without realising it? Dr Vonda Wright breaks down the importance of bone health and its impact on osteoporosis, Alzheimer’s, and longevity Dr Vonda Wright is an orthopaedic sports medicine surgeon and expert on active aging and mobility. She is the author of 44 research publications and of books such as, ‘Fitness After 40: Your Strong Body at 40, 50, 60, and Beyond’. In this conversation, Dr Vonda and Steven discuss topics such as, the truth about creatine for women, the early signs of arthritis, how running doesn’t build mus...
2025-03-061h 43What's it Worth? A Journal Club PodcastS3E1 (#18) - To Stay or Not To Stay with VKAs: Comparison of VKA or switch to DOAC in frail elderly patients with AFibWelcome to What's it Worth! Join your host, Dr. Diana Langworthy and student guest host, Meade Avery, as we walk the tightrope of anticoagulation in elderly patients with Atrial Fibrillation (AFib). We'll be reviewing an article that evaluated frail, elderly patients with AFib and compared maintaining INR guided warfarin with switching to a direct acting oral anticoagulant (DOAC). Come along as we decide To Stay or Not To Stay with VKAs! Key Points Atrial fibrillation leads to an increased risk of stroke/systemic embolism (SSE) and maintenance anticoagulation is indicated for patients at elevated risk Guidelines...
2025-03-0557 min
The Diary Of A CEO with Steven BartlettThe Manipulation Expert: Most People Don't Realise They're Narcissists! You're Setting Your Child Up For Misery!Are you being manipulated without knowing it? Robert Greene reveals the silent tactics of influence and how to take back control Robert Greene, returning for his third time on DOAC, is a world-renowned expert on human psychology and behaviour. He is also a multiple New York Times bestselling-author of 7 books such as, ‘The 48 Laws of Power’, ‘The Art of Seduction’ and ‘The 33 Strategies of War’.In this conversation, Robert and Steven discuss topics such as, how most people don’t realise they’re narcissists, the hidden cost of porn, why you’re setting...
2025-02-272h 43
The Diary Of A CEO with Steven BartlettBehavioural Psychologist: We're Not Having Enough Sex! Fat Makes You Attractive & The Poorer You Are The Friendlier You Are!Are we fighting against our own biology? Dr Bill von Hippel reveals how evolutionary psychology impacts love, success, and happiness. Dr Bill von Hippel is a renowned social psychologist, evolutionary specialist, and Professor of Psychology at the University of Queensland. He is the author of books such as, ‘The Social Leap: The New Evolutionary Science of Who We Are, Where We Come From, and What Makes Us Happy’. In this conversation, Dr Bill and Steven discuss topics such as, why high-achieving women struggle to find love, the top trait that ma...
2025-02-171h 56
Afya PodcastsPodcast #144: OPTIMAS trial: Quando posso iniciar DOAC no AVCi cardioembólico?Neste episódio, Vinícius Zofoli, médico intensivista e conteudista do Portal Afya, discute os resultados de um estudo clínico importante que comparou iniciar os DOAC em até 4 dias do AVC versus aguardar 7-12 dias do ictus. O estudo OPTIMAS, publicado recentemente no Lancet, muda a prática do intensivista no dia a dia. Aperte o play e ouça agora! Confira esse e outros posts no Portal Afya e siga nossas redes sociais! FacebookInstagramLinkedinTwitter
2025-02-0526 min
The Diary Of A CEO with Steven BartlettLeading Nutritional Scientist: Seed Oils Are Not Bad For You! Eating This Twice A Day Will Help Menopause! The Alarming Link Between Chewing & Belly Fat!Are seed oils dangerous? Is fasting the only way to lose weight? Is the carnivore diet the best way to eat? When health and diet advice has become a minefield, Dr Sarah Berry cuts through noise Dr Sarah Berry is a Professor in the Department of Nutritional Sciences at King's College London and Chief Scientist at ZOE. She is also the lead nutritional scientist on the PREDICT program, the world’s largest in-depth nutritional research programme. In this conversation, Dr Sarah and Steven discuss topics such as, the dangers of la...
2025-01-272h 12
The Diary Of A CEO with Steven BartlettThe Money Making Expert: The 7,11,4 Hack That Turns $1 Into $10K Per Month! This 90 Day Rule Will 10x Your Income! Daniel PriestleyThe world in 2025 has never felt more unsure, but using the newest technologies and timeless business advice, Daniel Priestly says this is the time for the biggest and most revolutionary opportunities to gain wealth Daniel Priestley is an award-winning serial entrepreneur who has built the entrepreneur accelerator company Dent Global and co-founded the quiz marketing platform Score App. He is the author of bestselling books such as, ‘Key Person of Influence’ and ‘Scorecard Marketing: The four-step playbook for getting better leads and bigger profits’. In this conversation, Daniel and Steven dis...
2025-01-202h 13
The Diary Of A CEO with Steven BartlettBrian Keating: I’m Spending $200 Million To Explore Why We Exist! How God Fits Into Science Finally Explained, Is God Real?Could understanding the mystery of the Big Bang and how the Universe came into creation mean that we can finally know for sure if there is a creator?Professor Brian Keating is a cosmologist and experimental physicist at the University of California San Diego. He is the host of the ‘Into The Impossible’ podcast and author of the books, ‘Losing The Nobel Prize’ and ‘Into The Impossible: Think Like A Nobel Prize Winner’. In this conversation, Brian and Steven discuss topics such as, how the discovery of the telescope changed the w...
2024-12-021h 51
The Diary Of A CEO with Steven BartlettScott Galloway (US ELECTION SPECIAL): “I bet $358,000 That They Win The Election!”, “33% Chance Trump Dies In Office!”, “Men Will Have Less Sex If Trump Wins!”On November 5th, the fate of America's future hangs in the balance, Scott Galloway is back to provide a preview on the 2 possible America'sScott Galloway is a Professor of Marketing at the New York Stern School of Business, and host of ‘The Prof G Show’ podcast. He is also the best-selling author of books such as, ‘The Algebra of Happiness’, ‘The Four’, and ‘The Algebra of Wealth’. In this conversation, Scott and Steven discuss topics such as; Scott’s gamble on the election outcome, how Trump’s victory could reshape US tax...
2024-11-041h 56
Fitness Coaching Secrets15. Podcast Review: Glucose Goddess On The DOACIn this episode, I share and discuss my thoughts on the episode from the DOAC with The Glucose Goddess, including:
Her best hacks for reducing/controlling your insulin response
Why I think it is too simplistic to categorize certain foods as sugar
The context I wish they included in terms of cravings and the dopamine response we get from sugar/starches
2024-10-1126 min
The Diary Of A CEO with Steven BartlettThe Brain Rot Dr: We're ALL Getting More Narcissistic!Welcoming back Dr Alok Kanojia onto DOAC for the second time, this conversation covers a variety of subjects from the search for purpose, the journey of healing, the loneliness epidemic to the role of dopamine in our lives, specifically around sex and relationships, amongst many more.Dr K is a psychiatrist and co-founder of the mental health coaching company 'Healthy Gamer', which aims to help with modern stressors, such as social media, video games, and online dating.You can order Dr Alok’s book, ‘How to Raise a Healthy Game...
2024-09-302h 37
DTB PodcastPsychotropic medicines in children, warfarin vs DOAC in old age, and fezolinetant in menopauseIn this podcast recorded in early July, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) continue to ignore political and sporting events and talk about the August issue of DTB. They discuss the editorial that highlights the growth in the use of psychotropic medication in children and young people and some of the challenges associated with this trend. They talk about a study that assessed the harms of changing frail older people with AF from warfarin to a DOAC. The main article is an overview of the evidence for fezolinetant for the treatment of menopausal vasomotor symptoms.
2024-07-3020 min
The Diary Of A CEO with Steven BartlettThe Manipulation Expert: CIA Spy Reveals You're Being Controlled! "You're Being Manipulated Without Realising It"! Andrew BustamanteThe REAL truth about the Trump assassination attempt from former CIA spy!Andrew Bustamante is a former covert CIA intelligence officer and US Air Force combat veteran. He is the founder of Everyday Spy, an online education platform that provides people with useful spy skills for everyday life. He is also the host of the ‘Everyday Spy Podcast’. In this episode, Andrew and Steven discuss topics such as, how to make a successful business sale, the myths around company culture, the key steps to manipulation, and the truth about Trump...
2024-07-292h 53
The Diary Of A CEO with Steven BartlettThe Fasting Expert: "The Truth About Ozempic", These 3 Foods Are Leading To Cancer! Our Supermarket Food Isn't Safe! - Dr Mindy PelzUnlocked: The hidden healing powers of fasting for your heart, hormones, and health.Dr Mindy Pelz is a world-renowned fasting and women’s health expert, specifically focusing on metabolic fasting, and the host of ‘The Resetter Podcast’. She is also the author of best-selling books such as, ‘The Reset Factor’, ‘The Menopause Reset’, ‘Fast Like A Girl’, and ‘Eat Like A Girl’. In this conversation, Mindy and Steven discuss topics such as, the secret to losing 18 pounds in 2 months, how to actually strip belly fat, the toolbox you need for optimal health, and...
2024-06-271h 59
REBEL CastANNEXA-1: Andexanet Alfa Associated with Harm in DOAC ReversalBackground: In May of 2018, Andexanet alfa gained accelerated approval by the FDA for the reversal direct oral anticoagulants (DOACs) despite a lack of robust evidence for use. The 2022 AHA/ASA guidelines give the drug a level 2A recommendation and recommend it over the use of 4F-PCC (Greenberg 2022). FDA approval alongside guideline endorsement has led to the drug seeing a remarkable growth in use without a single high-quality study to support its use. The available data reports good hemostatic control: a subjective measure that is highly biased by unblinding and selection bias. More importantly, there are no studies...
2024-05-2300 min
The Calum Johnson Show50K Q&A - Why I Quit, Did We Copy DOAC & How Anyone Can Get Their First 50K SubsFollow Us!
Instagram: https://www.instagram.com/calumjohnson1/?hl=en
Twitter: https://twitter.com/calum_johnson9
Timestamps
00:00 Intro
01:06 How I went from 9 to 5 to doing a podcast in 18 months (The podcast origin story)
08:27 How you can go from 0-50k subscribers.
14:38 Was there ever a moment where I thought it wouldn't work, (I was broke & stressed!)19:17 Did we copy the DOAC?
22:36 How has life changed after getting views?
2024-04-0131 minThe Diary Of A CEO with Steven BartlettThe Top 7 Belly Fat Burning Hacks For 2024 That Are PROVEN To Work!As a holiday wrap-up, we’ve listened to you and answered one of the most popular questions; What is your favourite EVER episode?But, we think the more important question is what is YOUR favourite episode on the Diary of CEO of all time. Using our in-house data scientist and a group of analysts, we’ve found the most replayed and shared moments from 2023. This should be the most valuable episode you will ever listen to.7th Most Replayed Moment, Dr. Giles Yeo.Dr Giles takes on some of the bigg...
2023-12-261h 17
日経メディカル 聴く論文149.日経メディカル 聴く論文（2023.11.27-12.01） フレイル＋心房細動に処方しやすいDOACは？ 他2023年11月27日から12月1日に日経メディカル Onlineで紹介した5本の海外医学論文のエッセンスを日本語音声でお届けします。
①JAMA Network Open誌から フレイル＋心房細動に処方しやすいDOACは？
②BMJ誌から 帯状疱疹生ワクチンの有効性の持続期間は？
③JAMA Cardiology誌から ダパグリフロジン投与開始直後のeGFR低下は問題ない
④NEJM誌から ボツリヌス毒素は本態性頭部振戦にも有効
⑤NEJM誌から IgA腎症に対する新規抗体薬の第2相臨床試験
2023-11-3010 min
NGMC Continuing Medical EducationGHI Grand Rounds: DOAC's and the New Factor XI Anti-thrombotic TherapiesTitle: Cardiology Grand Rounds: Lessons Learned from DOAC's and the New Factor XI Anti-thrombotic Therapies Being Studied
Speaker: Manesh R. Patel, MD
Chief, Division of Cardiology
Co-Director, Duke Heart Center
Duke Clinical Research Institute
Duke University, Durham, NC
Disclosures:
Research Grants: PACIFIC-AF: Bayer, Janssen, Heartflow, Idorsia, NHLBI, Novartis
Advisory Board/Consulting: Bayer, Janssen, Heartflow, Medscape
Objectives:
•Understand the Net-Benefit of Warfarin and then NOACs in AFib
•Understand the use of NOACs and limitations
•Understand the Factor XI therapy and promise in A. Fib
2023-09-191h 05
Discussing essential topics related to Clinical Pharmacists in General PracticeConducting DOAC Reviews in Primary Care: What do you need to know?Conducting DOAC Reviews in Primary Care: What do you need to know?Join us for the latest episode of our new clinical series, where we dive into the topic of DOACs (Direct Oral Anticoagulants). In this episode, we discuss this topic with Angelina Soliman, a Senior IP Pharmacist who specialises in Atrial Fibrillation and Anticoagulation. Also adding to the conversation is my co-host, Ruhina Kassam, who is a Senior IP Pharmacist and the Training and Development Lead of Clinical Pharmacist Solutions.Together, we explore the benefits of switching your patients from Warfarin to DOACs and...
2023-07-1917 min
NEUROPODSTAGIONE 3 EPISODIO 34 - Stroke on DOAC treat or threatPODCASTER SENIOR: Andrea Zini;PODCASTER JUNIOR: Gabriele Prandin;RAZIONALE: Gli anticoagulanti orali diretti (DOAC) contro il fattore Xa e IIa hanno rivoluzionato le terapie per i pazienti con disturbi trombo-embolici, in particolare il cardioembolismo da Fibrillazione atriale non valvolare. Questa classe di farmaci che comprende Apixaban, Rivaroxaban, Edoxaban e Dabigatran ha dimostrato la sua superiorità nel diminuire il rischio emorragico sistemico ed intracranico e la medesima efficacia nel prevenire eventi ischemici cerebrali se paragonati al warfarin, come confermato da una metanalisi di trial clinici randomizzati pubblicata su Circulation nel 2022 che includeva circa 71000 pazienti. La diffusione d...
2023-06-1314 min
The Authentic Man Podcast with David Chambers: Dating, Relationship, Masculinity & Intimacy Guidance For MenWeekly Mini-Episode: My thoughts on Chris Williamson & Steven Bartlett's DOAC episode about dating and how men can up-level their dating chancesIn this week's mini-episode, I talk about an episode of the DOAC where Chris Williamson & Steven Bartlett speak about many things, but I will focus on what they talk about and ways that men, in particular, can improve their dating chances and lives. Things I cover: 🔥 How men can up-level their dating lives 🔥 Women aren't just looking for men with money and education. There is another huge thing they want 🔥 How to be more sexually confident 🔥 Where I think Chris Williamson is wrong 🔥 Why the episode makes you...
2023-04-1626 minThe Diary Of A CEO with Steven BartlettThe No.1 Health Expert: The One Food (WE ALL EAT) That's Slowly Hurting Us!: Max LugavereMax Lugavere is a foremost expert on the brain and how we can get the best out of it. A New York Times and Wall Street Journal best-selling author, his books 'Genius Foods', 'Genius Life' and 'Genius Kitchen' have ushered in a new way of seeing how what we eat effects how effective our brain is. What few know about Max is that his best-selling books come from deeply heartfelt motivation, as he saw his mother lost to dementia.Ever since that terrible day he's had one focus and one focus only - what can people do...
2023-02-201h 52
Questioning Medicine207. Medical Update-- DOAC, Warfarin, diabetes, venous thromboembolism, EMPA-KIDNEY, EmpagliflozinEfficacy and Safety of Intensive Versus Nonintensive Supplemental Insulin With a Basal-Bolus Insulin Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Clinical Study | Diabetes Care | American Diabetes Association (diabetesjournals.org) randomized noninferiority study from Emory University, 224 hospitalized patients with longstanding type 2 diabetes Both groups received basal/bolus insulin; both the starting dose and subsequent changes were specified by the study protocol. Additional premeal SSI was added to scheduled premeal bolus doses.randomized to either intensive SSI (at BG >140 mg/dL) or nonintensive SSI (at BG >260 mg/dL) before meals...
2023-02-0917 min
Primary Care SpotlightAudit Tool for DOAC Prescribing in General PracticeIn this episode of primary care spotlight Emma speaks with pharmacist David Jenkins about an audit tool for DOAC prescribing in general practice. David is a Fellow of the Royal Pharmaceutical Society and a member of the South Kerrier Primary Care Network Pharmacy Team. The team were highly commended in the recent General Practice Awards, and in October won a prestigious national Health Services Journal Patient Safety Award for their project Audit Tool for DOAC Prescribing in General Practice.
2023-02-0617 minThe Diary Of A CEO with Steven Bartlett5 Scientific Rules for Making & Breaking Habits!In this episode I wanted to do something that I haven't done in a while. It's been too long since it was just me, the microphone, and you. If there's one request I get over and over again, it's for more episodes of DOAC like in our early years, just me what's front of my mind - an authentic 'Diary of a CEO'.It's been an incredible 2022, our level of guest and conversation has only got higher and higher, but I wanted to look forward to 2023. Specifically, something that's been on my mind lately, how do you...
2022-12-2957 min
ValveCastClick Valvar #361 - Uso dos DOAC’s em próteses mecânicasNo Click Valvar de hoje temos grandes insights sobre o uso dos DOAC’s em próteses mecânicas.
2022-10-1303 minValveCastClick Valvar #346 - Posologia dos DOAC’sNo Click Valvar de hoje vamos falar sobre a Posologia dos DOAC’s.
2022-08-2203 min
Medical Digest & Congress ReportStrategies for Assessing and Managing DOAC-Related Bleeding - report from ISTH2022Professor Deborah Siegal chaired an interesting symposium during the ISTH 2022 congress in London, the topic was strategies for assessing and managing DOAC-related bleeding.
Video: https://congressreport.eu/scientific-contents/interview:strategies-assessing-and-managing-doac-related-bleeding
2022-07-2610 min
Emergency Medical MinutePodcast 789: DOACContributor: Aaron Lessen, MD Educational Pearls: Direct Oral Anticoagulants (DOACs) have surpassed Warfarin and Lovenox® for anticoagulation as they do not require injection and allow for easier discharge. In the ED, they are commonly prescribed after PE or DVT diagnosis. Common DOACs are Apixaban (Eliquis®) and Rivaroxaban (Xarelto®). There has not been a direct head to head study comparing outcomes. 2 large observational studies evaluated the recurrence of clots and bleeding risk in patients with newly prescribed Eliquis® or Xarelto® for DVT or PE. Both studies found that Eliquis® had superior outcomes. Further data is required to determine...
2022-06-1303 min
CardioAulaTratando paciente com DOAC’s de forma eficaz e segura I PodCast CardioAula® #196Dr. Halsted Gomes disserta sobre o artigo Atlantis trial. O estudo explica se podemos utilizar DOAC’s após a TAVI e obter a mesma eficácia e segurança que a terapia padrão.
2022-05-0709 minQuestioning Medicine195. Medical Update-- GERD guidelines, IV iron, bariatric surgery, DOAC and the Frail PmtsEuropean Heart JournalBariatric surgery and cardiovascular disease: a systematic review and meta-analysisEur Heart J 2022 Mar 04;[EPub Ahead of Print], SL van Veldhuisen, TM Gorter, G van Woerden, RA de Boer, M Rienstra, EJ Hazebroek, DJ van Veldhuisen 39 studies, all prospective or retrospective cohort studies, showed Bariatric surgery is associated with a reduced hazard ratio (HR) of CV morality (0.59), all-cause mortality (0.55), incident HF (0.50), myocardial infarction (0.58) and stroke (0.64) Authors state “”The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced...
2022-05-0525 minValveCastClick Valvar#314 - DOAC's na Estenose MitralNo Click Valvar de hoje, temos insights sobre um aspecto interessante sobre o uso dos DOAC's na Estenose Mitral!
2022-05-0202 minValveCastClick Valvar#310 - Uso dos DOAC's nas ValvopatiasNo Click Valvar de hoje, temos insights sobre um aspecto interessante, os aspectos clínicos relevantes sobre o uso dos DOAC's nas valvopatias!
2022-04-1805 min
Questioning Medicine174. Gestational Diabetes Screening, DOAC for Valvular Afib, COVID19, SemaglutideDOAC are just as safe if not safer for warfarin for valvular afib (NOT valve replacement but moderate to severe mitral stenosis). Please, just give normal lovenox for covid patients. Stop DM drugs in the elderly cause no-glycemia is more dangerous than hyperglycemia. semaglutide works as along as you keep taking it. gestational diabetes screening should be a two stop process. Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation: A Population-Based Cohort Study: Annals of Internal Medicine: Vol 0, No 0 (acpjournals.org) researchers did a New-user retrospective...
2021-04-0421 min
ACEP Frontline - Emergency MedicineDOAC Reversal in the ED with Drs. Colin Kaide and Eric CucchiIn this week’s episode, we’re joined by Colin Kaide, MD, an Emergency Physician with Wexner Medical Center at The Ohio State University, and Eric W. Cucchi MS, PA-C, is the Director of Operations, eICU Support Center at UMass Memorial Medical Center. With stroke being one of the top 3 causes of death in the nation, timing is everything! Join the conversation to listen as they share insights into the rapid reversal of DOAC-associated bleeding and practical strategies for aligning clinical practice with local hospital bleeding management protocols.
Support for this episode provided through a grant from Spire Learning.
2021-02-1537 min
PERTcastDedicated DOAC Trials for the Treatment of Pulmonary Embolism: Part 3The PERT Consortium invites you to listen to a podcast moderated by past immediate president of PERT Consortium Victor Tapson, MD, and joined by Alex Spyropoulos, MD, as they discuss extension of VTE treatment with a DOAC to reduce the risk of recurrence and the 2019 ESC Guidelines on extension of treatment.
2020-09-2400 min
PERTcastDedicated DOAC Trials for the Treatment of Pulmonary Embolism: Part 1The PERT Consortium invites you to listen to a podcast moderated by past immediate president of PERT Consortium Victor Tapson, MD, and joined by Alex Spyropoulos, MD, as they discuss dedicated DOAC trials that evaluated the treatment of pulmonary embolism.
2020-09-0800 min
ドクターサロン「ワルファリンとDOAC」（2020813放送）「ワルファリンとDOAC」について、（解 説）聖路加国際病院心臓血管外科医長 阿部恒平氏（ききて）葵会柏たなか病院糖尿病センター長 山内俊一氏
2020-08-2000 min
FarmacologiaDOAc: introduzione.#salute #anatomia #esameobiettivo #farmaci #farmacologia #fisiologia #infermieri #medici #medicina #semeiotica #terapia #studenti #rianimazione #emergenze #urgenze #cuore #fibrillazione #dabigatrna #apixaban #rivaroxaban #edoxaban #anticoagulanti #coagulazione #emorragia #trombosi #embolia #tromboembolismoBenvenuti nel canale di podcast della serie “pillole di medicina”. Questo progetto audio ha finalità puramente didattiche e divulgative ed è indirizzato a giovani apprendisti del settore sanitario quale supporto per lo studio e l'approfondimento personale in relazione a tematiche generali di medicina e semeiotica clinica.L'iniziativa è parte integrante dei progetti formativi della Società Scientifica di Medicina Diagnostica e Terapeutica (SIMEDET), società multidisciplinare dedicata a studenti di medicina, infermieri, medici specialisti e non. Il p...
2020-01-3008 min
Blood Advances TalksManaging patients who are receiving warfarin (or DOAC)and need an elective surgery or procedureManaging patients who are receiving warfarin (or DOAC)and need an elective surgery or procedure by Blood Advances Talks
2019-06-2521 min
MDedge CardiocastStroke risk, DOAC type in nonvalvular A-Fib patientsThis week's top stories in clinical medicine: Single-center study outlines stoke risk, DOAC type in nonvalvular A-fib patients ACOG guidance addresses cardiac contributors to maternal mortality Higher serum leptin levels associated with PAD Employed physicians now outnumber independent doctors
2019-05-1007 min
CorConsult Rx: Evidence-Based Medicine and PharmacyThe DOAC Reversal Controversy ft Dr. Brian GilbertOn this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We recently had a paper publish in the American Journal of Emergency Medicine (Dr. Gilbert was the lead author). The name of the article and link can be found below: Throwing it in reverse: An update...
2019-04-1252 minCorConsult Rx: Evidence-Based Medicine and PharmacyThe DOAC Reversal Controversy ft Dr. Brian GilbertOn this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We recently had a paper publish in the American Journal of Emergency Medicine (Dr. Gilbert was the lead author). The name of the article and link can be found below: Throwing it in reverse: An update...
2019-04-1252 min
CorConsult Rx: Evidence-Based Medicine and PharmacyThe DOAC Reversal Controversy ft Dr. Brian GilbertOn this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We recently had a paper publish in the American Journal of Emergency Medicine (Dr. Gilbert was the lead author). The name of the article and link can be found below: Throwing...
2019-04-1252 min
DTB podcastApril 2019: DOAC dosing in renal impairmentIn April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the challenges of prescribing direct acting oral anticoagulant (DOAC) drugs for people with renal impairment. The editors also talk about the use of saline nasal irrigation and discuss central sensitisation syndrome.
Read the issue online: https://dtb.bmj.com/content/57/4.
2019-03-2710 minDTB PodcastApril 2019: DOAC dosing in renal impairmentIn April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the challenges of prescribing direct acting oral anticoagulant (DOAC) drugs for people with renal impairment. The editors also talk about the use of saline nasal irrigation and discuss central sensitisation syndrome.
Read the issue online: https://dtb.bmj.com/content/57/4.
2019-03-2010 min
SCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.
2016-12-0130 minSCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.
2016-12-0130 minSCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.
2016-12-0130 min