Shows
The Diary Of A CEO with Steven BartlettChris Eubank Jr: I Was Paid $**** For The Fight! The Night Before, My Dad Finally Opened Up!He silenced the critics, defied the odds, and walked through fire - Chris Eubank Jr. tells the full story of one of 2025’s most unforgettable fights.
Chris Eubank Jr. is a world-class professional boxer, middleweight contender, and son of the legendary former professional boxer, Chris Eubank Sr. In April 2025, he won against Connor Benn in one of the most highly anticipated fights in British boxing history.
He discusses:
Why he refused to shake Conor Benn’s hand.
Why the fight almost collapsed the night before.
...2025-05-081h 48
The Elective Rotation - A Critical Care Pharmacy Podcast1021: How Long Is the Duration of DOAC Interference With Heparin Anti-Xa Levels?Show notes at pharmacyjoe.com/episode1021.
In this episode, I'll discuss the duration of DOAC interference with heparin anti-Xa levels.
The post 1021: How Long Is the Duration of DOAC Interference With Heparin Anti-Xa Levels? appeared first on Pharmacy Joe.
2025-04-2804 minThe Elective Rotation: A Critical Care Hospital Pharmacy Podcast1021: How Long Is the Duration of DOAC Interference With Heparin Anti-Xa Levels?Show notes at pharmacyjoe.com/episode1021.
In this episode, I'll discuss the duration of DOAC interference with heparin anti-Xa levels.
The post 1021: How Long Is the Duration of DOAC Interference With Heparin Anti-Xa Levels? appeared first on Pharmacy Joe.
2025-04-2804 min
Brilliant Board Review & CME🎙️ Episode 42: DOACs Decoded: When to Dabble, When to DodgeSend us a text🧠 Clinical ContextDOACs (Direct Oral Anticoagulants) have revolutionized anticoagulation—goodbye routine INRs, hello convenience. But while they’ve made our lives easier, they’re not always a fit for every scenario. Here's how to navigate the DOAC jungle.✅ When DOACs Are PreferredVenous Thromboembolism (VTE)Atrial Fibrillation⚠️ Exclude patients with:Mechanical heart valvesRheumatic mitral valve disease (That’s why cardiologists note “non-rheumatic” AF in their documentation—treatment plan hinges on it.)⛔ When DOACs Are a No-GoMechanical Heart Valves → Warfarin only...2025-04-2103 min
The Diary Of A CEO with Steven BartlettMasculinity Debate: Are Dating Apps Creating A Generation Of Incels?! Lonely Men Are More Dangerous Than Ever!Are we raising a lost generation of men? Is society failing young boys? In this emergency discussion, Steven sits down with expert guests to explore the recently published ‘Lost Boys Report’.
Scott Galloway is a professor of marketing at NYU Stern School of Business and a member of the advisory council for the American Institute for Boys and Men. Logan Ury is a behavioral scientist turned dating coach and the Director of Relationship Science at Hinge. Together, they bring expertise in culture, psychology, and societal trends to unpack the crisis highlighted in the Lost Boys...2025-03-312h 25
Last Week in MedicineHalf Dose DOAC for Long Term VTE Prevention, Biomarker Guided Antibiotics for Sepsis, GPT-4 Assistance for Physicians, Optimal Vasopressin Initiation for Shock, DOAC vs No AC for A fib After Intracerebral Hemorrhage, HFNC vs NIV for Respiratory FailureFor this episode we are joined by EBM guru, Dr. Brian Locke, who deftly breaks down all of our statistics questions. Is half dose DOAC as good as full dose DOAC for preventing VTE, and does it reduce bleeding risk? Can procalcitonin reduce duration of antibiotics for infections without compromising mortality rates? Can LLMs like GPT-4 help physicians manage patients better? Can reinforcement learning models predict when to start vasopressin in patients with septic shock? What is the risk of resuming anticoagulation in patients with atrial fibrillation and prior intracerebral hemorrhage? Is high flow nasal cannula as g...2025-03-271h 32The Diary Of A CEO with Steven BartlettEMERGENCY DEBATE: They Lied About The Economy Recovering! Is A Financial Apocalypse Coming?Is the economy on the brink of collapse? Gary Stevenson and Daniel Priestley break down the emergency financial crisis no one is talking aboutThe Diary Of A CEO’s economics debate is joined by 2 experts: Gary Stevenson and Daniel Priestley. Gary Stevenson is a British economist, former financial trader, and author of The Trading Game. Daniel Priestly is an award-winning serial entrepreneur who has written 5 books on starting and scaling businesses.In this conversation, Gary, Daniel, and Steven discuss topics such as, whether there is a financial apocalypse lo...2025-03-202h 25
The Diary Of A CEO with Steven BartlettThe Speaking Coach: The One Word All Liars Use! Stop Saying This Word, It's Making You Sound Weak! The More You Do This, The More You Sound Like A Liar!How do you communicate like a top lawyer and command respect? Jefferson Fisher reveals the courtroom-tested tricks that win cases AND everyday conversations Jefferson Fisher is a trial lawyer, communication expert, and host of ‘The Jefferson Fisher Podcast’, where he teaches how to communicate with confidence. He is also the bestselling author of the upcoming book, ‘The Next Conversation: Argue Less, Talk More’. In this conversation, Jefferson and Steven discuss topics such as, how to make people agree with you instantly, the body language tricks that make you sound powerful...2025-03-172h 17
The Diary Of A CEO with Steven BartlettDr. Joe Dispenza: Secret To Living Without Fear & Anxiety Forever! Your Mind Can Heal Itself! Stress Is The Root Of 90% Of All Diseases!What if 95% of your life is controlled by your subconscious mind? Dr Joe Dispenza reveals how to break free and reprogram your mind for success Dr Joe Dispenza is a researcher, lecturer, and corporate consultant who has developed a practical formula to help people transform their lives. He is also the best-selling author of books such as, ‘Becoming Supernatural: How Common People Are Doing the Uncommon’ and ‘You Are the Placebo: Making Your Mind Matter’. In this conversation, Dr Joe and Steven discuss topics such as, the link between stress and...2025-03-131h 51
The Diary Of A CEO with Steven BartlettThe Public Speaking Expert: This Speaking Mistake Makes People Ignore You! These Small Mistakes Make You Unlikeable!Speaking with confidence isn’t a gift, it’s a skill - Vinh Giang reveals the blueprint to mastering the art of communicationVinh Giang is an award-winning entrepreneur, part-magician, and full time communication coach. He runs masterclasses and has helped thousands of people improve their communication and vocal skills.In this conversation, Vinh and Steven discuss topics such as, the top speaking mistake that makes people ignore you, small mistakes that make you unlikeable, how to effortlessly speak with power and confidence, and the number one word to avoi...2025-03-102h 26
The Diary Of A CEO with Steven BartlettThe Ageing Doctor: These Are They Early Signs Of Arthritis! If You Run & Don't Do This, Start Now! The Secret Cause of Alzheimer's!Could you be losing bone strength without realising it? Dr Vonda Wright breaks down the importance of bone health and its impact on osteoporosis, Alzheimer’s, and longevity Dr Vonda Wright is an orthopaedic sports medicine surgeon and expert on active aging and mobility. She is the author of 44 research publications and of books such as, ‘Fitness After 40: Your Strong Body at 40, 50, 60, and Beyond’. In this conversation, Dr Vonda and Steven discuss topics such as, the truth about creatine for women, the early signs of arthritis, how running doesn’t build mus...2025-03-061h 42
What's it Worth? A Journal Club PodcastS3E1 (#18) - To Stay or Not To Stay with VKAs: Comparison of VKA or switch to DOAC in frail elderly patients with AFibWelcome to What’s it Worth! Join your host, Dr. Diana Langworthy and student guest host, Meade Avery, as we walk the tightrope of anticoagulation in elderly patients with Atrial Fibrillation (AFib). We'll be reviewing an article that evaluated frail, elderly patients with AFib and compared maintaining INR guided warfarin with switching to a direct acting oral anticoagulant (DOAC). Come along as we decide To Stay or Not To Stay with VKAs! Key Points Atrial fibrillation leads to an increased risk of stroke/systemic embolism (SSE) and maintenance anticoagulation is indicated for patients at elevated risk Gui...2025-03-0557 min
The Diary Of A CEO with Steven BartlettThe Manipulation Expert: Most People Don't Realise They're Narcissists! You're Setting Your Child Up For Misery!Are you being manipulated without knowing it? Robert Greene reveals the silent tactics of influence and how to take back control Robert Greene, returning for his third time on DOAC, is a world-renowned expert on human psychology and behaviour. He is also a multiple New York Times bestselling-author of 7 books such as, ‘The 48 Laws of Power’, ‘The Art of Seduction’ and ‘The 33 Strategies of War’.In this conversation, Robert and Steven discuss topics such as, how most people don’t realise they’re narcissists, the hidden cost of porn, why you’re setting...2025-02-272h 43
The Diary Of A CEO with Steven BartlettBehavioural Psychologist: We're Not Having Enough Sex! Fat Makes You Attractive & The Poorer You Are The Friendlier You Are!Are we fighting against our own biology? Dr Bill von Hippel reveals how evolutionary psychology impacts love, success, and happiness. Dr Bill von Hippel is a renowned social psychologist, evolutionary specialist, and Professor of Psychology at the University of Queensland. He is the author of books such as, ‘The Social Leap: The New Evolutionary Science of Who We Are, Where We Come From, and What Makes Us Happy’. In this conversation, Dr Bill and Steven discuss topics such as, why high-achieving women struggle to find love, the top trait that ma...2025-02-171h 56
Afya PodcastsPodcast #144: OPTIMAS trial: Quando posso iniciar DOAC no AVCi cardioembólico?Neste episódio, Vinícius Zofoli, médico intensivista e conteudista do Portal Afya, discute os resultados de um estudo clínico importante que comparou iniciar os DOAC em até 4 dias do AVC versus aguardar 7-12 dias do ictus. O estudo OPTIMAS, publicado recentemente no Lancet, muda a prática do intensivista no dia a dia. Aperte o play e ouça agora!
Confira esse e outros posts no Portal Afya e siga nossas redes sociais!
Facebook
Instagram
Linkedin
Twitter
2025-02-0526 min
Afya PodcastsPodcast #144: OPTIMAS trial: Quando posso iniciar DOAC no AVCi cardioembólico?Neste episódio, Vinícius Zofoli, médico intensivista e conteudista do Portal Afya, discute os resultados de um estudo clínico importante que comparou iniciar os DOAC em até 4 dias do AVC versus aguardar 7-12 dias do ictus. O estudo OPTIMAS, publicado recentemente no Lancet, muda a prática do intensivista no dia a dia. Aperte o play e ouça agora! Confira esse e outros posts no Portal Afya e siga nossas redes sociais! FacebookInstagramLinkedinTwitter2025-02-0526 min
The Diary Of A CEO with Steven BartlettLeading Nutritional Scientist: Seed Oils Are Not Bad For You! Eating This Twice A Day Will Help Menopause! The Alarming Link Between Chewing & Belly Fat!Are seed oils dangerous? Is fasting the only way to lose weight? Is the carnivore diet the best way to eat? When health and diet advice has become a minefield, Dr Sarah Berry cuts through noise Dr Sarah Berry is a Professor in the Department of Nutritional Sciences at King's College London and Chief Scientist at ZOE. She is also the lead nutritional scientist on the PREDICT program, the world’s largest in-depth nutritional research programme. In this conversation, Dr Sarah and Steven discuss topics such as, the dangers of la...2025-01-272h 11
The Diary Of A CEO with Steven BartlettThe Money Making Expert: The 7,11,4 Hack That Turns $1 Into $10K Per Month! This 90 Day Rule Will 10x Your Income! Daniel PriestleyThe world in 2025 has never felt more unsure, but using the newest technologies and timeless business advice, Daniel Priestly says this is the time for the biggest and most revolutionary opportunities to gain wealth Daniel Priestley is an award-winning serial entrepreneur who has built the entrepreneur accelerator company Dent Global and co-founded the quiz marketing platform Score App. He is the author of bestselling books such as, ‘Key Person of Influence’ and ‘Scorecard Marketing: The four-step playbook for getting better leads and bigger profits’. In this conversation, Daniel and Steven dis...2025-01-202h 13
The Diary Of A CEO with Steven BartlettBrian Keating: I’m Spending $200 Million To Explore Why We Exist! How God Fits Into Science Finally Explained, Is God Real?Could understanding the mystery of the Big Bang and how the Universe came into creation mean that we can finally know for sure if there is a creator?Professor Brian Keating is a cosmologist and experimental physicist at the University of California San Diego. He is the host of the ‘Into The Impossible’ podcast and author of the books, ‘Losing The Nobel Prize’ and ‘Into The Impossible: Think Like A Nobel Prize Winner’. In this conversation, Brian and Steven discuss topics such as, how the discovery of the telescope changed the w...2024-12-021h 51
The Diary Of A CEO with Steven BartlettScott Galloway (US ELECTION SPECIAL): “I bet $358,000 That They Win The Election!”, “33% Chance Trump Dies In Office!”, “Men Will Have Less Sex If Trump Wins!”On November 5th, the fate of America's future hangs in the balance, Scott Galloway is back to provide a preview on the 2 possible America'sScott Galloway is a Professor of Marketing at the New York Stern School of Business, and host of ‘The Prof G Show’ podcast. He is also the best-selling author of books such as, ‘The Algebra of Happiness’, ‘The Four’, and ‘The Algebra of Wealth’. In this conversation, Scott and Steven discuss topics such as; Scott’s gamble on the election outcome, how Trump’s victory could reshape US tax...2024-11-041h 56
Weiter im Chaos#119 - Human Performance: Zwischen Technologie-Hype und Achtsamkeit – Wo liegt der Sweet Spot?In dieser Episode diskutieren Arns und ich das spannende Konzept der Human Performance 💪. Wir tauchen tief in verschiedene Aspekte wie Schlaf, körperliche Fitness, emotionale Intelligenz und Motivation ein. Dabei reflektieren wir darüber, wie Technologie uns bei der Selbstüberwachung unterstützt – manchmal ist sie unglaublich hilfreich, aber manchmal auch ganz schön belastend 🤖. Außerdem betonen wir die Bedeutung von Achtsamkeit und Meditation, um das perfekte Gleichgewicht zwischen Leistung und persönlichem Wohlbefinden zu finden 🧘♂️.
3 Take Aways:
Human Performance - No Brainer, aber es beinhaltet körperliche und mentale Fitness
Für jede Person bedeutet Per...2024-10-2130 min
Fitness Coaching Secrets15. Podcast Review: Glucose Goddess On The DOACIn this episode, I share and discuss my thoughts on the episode from the DOAC with The Glucose Goddess, including:
Her best hacks for reducing/controlling your insulin response
Why I think it is too simplistic to categorize certain foods as sugar
The context I wish they included in terms of cravings and the dopamine response we get from sugar/starches
2024-10-1126 min
The Diary Of A CEO with Steven BartlettThe Brain Rot Dr: We're ALL Getting More Narcissistic!Welcoming back Dr Alok Kanojia onto DOAC for the second time, this conversation covers a variety of subjects from the search for purpose, the journey of healing, the loneliness epidemic to the role of dopamine in our lives, specifically around sex and relationships, amongst many more.Dr K is a psychiatrist and co-founder of the mental health coaching company 'Healthy Gamer', which aims to help with modern stressors, such as social media, video games, and online dating.You can order Dr Alok’s book, ‘How to Raise a Healthy Game...2024-09-302h 38
JournalFeedAre DOACs A Contra-indications | Late TNK for LVO StrokesThe JournalFeed podcast for the week of August 5-9, 2024.Monday Spoon Feed: For acute ischemic stroke patients with recent DOAC ingestion who (1) had their DOAC level measured, (2) had DOAC reversal with idarucizumab, or (3) inadvertently received thrombolytics with DOAC subsequently discovered, there was not evidence of increased significant intracranial hemorrhage associated with off-label thrombolytic therapy.Friday Spoon Feed:In patients with large vessel occlusions(LVO) presenting 4.5-24 hours after onset, without access to endovascular thrombectomy (ET), tenecteplase(TNK) administration bested standard medical treatment(SMT) in 90-day disability-free recovery.2024-08-1009 min
touchPODCASTIntracranial haemorrhage related to direct oral anticoagulant medications: Latest evidence for reversal strategiestouchTALKS for touchNEUROLOGY
A thrombosis and haemostasis expert shares insights into reversal strategies for patients with direct oral anticoagulant-associated intracranial haemorrhage (DOAC-ICH), including benefits and risks of DOAC use, evidence for DOAC reversal agents and guideline-directed management of the condition.
The expert
Prof. Dr. med. Jan Beyer-Westendorf, University Hospital Carl Gustav Carus, Dresden, Germany
This touchPODCAST is for HCPs outside of the UK only.
This activity is funded by an independent medical education grant from AstraZeneca. This activity is jointly provided by USF Health and touchIME.
For further information v...2024-08-0547 mintouchPODCASTIntracranial haemorrhage related to direct oral anticoagulant medications: Latest evidence for reversal strategiestouchTALKS for touchCARDIO
A thrombosis and haemostasis expert shares insights into reversal strategies for patients with direct oral anticoagulant-associated intracranial haemorrhage (DOAC-ICH), including benefits and risks of DOAC use, evidence for DOAC reversal agents and guideline-directed management of the condition.
The expert
Prof. Dr. med. Jan Beyer-Westendorf, University Hospital Carl Gustav Carus, Dresden, Germany
This touchPODCAST is for HCPs outside of the UK only.
This activity is funded by an independent medical education grant from AstraZeneca. This activity is jointly provided by USF Health and touchIME.
For further information v...2024-08-0547 min
DTB PodcastPsychotropic medicines in children, warfarin vs DOAC in old age, and fezolinetant in menopauseIn this podcast recorded in early July, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) continue to ignore political and sporting events and talk about the August issue of DTB. They discuss the editorial that highlights the growth in the use of psychotropic medication in children and young people and some of the challenges associated with this trend. They talk about a study that assessed the harms of changing frail older people with AF from warfarin to a DOAC. The main article is an overview of the evidence for fezolinetant for the treatment of menopausal vasomotor symptoms.
2024-07-3020 min
The Diary Of A CEO with Steven BartlettThe Manipulation Expert: CIA Spy Reveals You're Being Controlled! "You're Being Manipulated Without Realising It"! Andrew BustamanteThe REAL truth about the Trump assassination attempt from former CIA spy!Andrew Bustamante is a former covert CIA intelligence officer and US Air Force combat veteran. He is the founder of Everyday Spy, an online education platform that provides people with useful spy skills for everyday life. He is also the host of the ‘Everyday Spy Podcast’. In this episode, Andrew and Steven discuss topics such as, how to make a successful business sale, the myths around company culture, the key steps to manipulation, and the truth about Trump...2024-07-292h 54
The Diary Of A CEO with Steven BartlettThe Fasting Expert: "The Truth About Ozempic", These 3 Foods Are Leading To Cancer! Our Supermarket Food Isn't Safe! - Dr Mindy PelzUnlocked: The hidden healing powers of fasting for your heart, hormones, and health.Dr Mindy Pelz is a world-renowned fasting and women’s health expert, specifically focusing on metabolic fasting, and the host of ‘The Resetter Podcast’. She is also the author of best-selling books such as, ‘The Reset Factor’, ‘The Menopause Reset’, ‘Fast Like A Girl’, and ‘Eat Like A Girl’. In this conversation, Mindy and Steven discuss topics such as, the secret to losing 18 pounds in 2 months, how to actually strip belly fat, the toolbox you need for optimal health, and...2024-06-272h 00
REBEL EM – Emergency Medicine BlogANNEXA-1: Andexanet Alfa Associated with Harm in DOAC ReversalBackground: In May of 2018, Andexanet alfa gained accelerated approval by the FDA for the reversal direct oral anticoagulants (DOACs) despite a lack of robust evidence for use. The 2022 AHA/ASA guidelines give the drug a level 2A recommendation and recommend it over the use of 4F-PCC (Greenberg 2022). FDA approval alongside guideline endorsement has led to the drug seeing a remarkable growth in use without a single high-quality study to support its use. The available data reports good hemostatic control: a subjective measure that is highly biased by unblinding and selection bias. More importantly, there are no studies...2024-05-2300 minREBEL CastANNEXA-1: Andexanet Alfa Associated with Harm in DOAC ReversalBackground: In May of 2018, Andexanet alfa gained accelerated approval by the FDA for the reversal direct oral anticoagulants (DOACs) despite a lack of robust evidence for use. The 2022 AHA/ASA guidelines give the drug a level 2A recommendation and recommend it over the use of 4F-PCC (Greenberg 2022). FDA approval alongside guideline endorsement has led to the drug seeing a remarkable growth in use without a single high-quality study to support its use. The available data reports good hemostatic control: a subjective measure that is highly biased by unblinding and selection bias. More importantly, there are no studies...2024-05-2300 min
The Calum Johnson Show50K Q&A - Why I Quit, Did We Copy DOAC & How Anyone Can Get Their First 50K SubsFollow Us!
Instagram: https://www.instagram.com/calumjohnson1/?hl=en
Twitter: https://twitter.com/calum_johnson9
Timestamps
00:00 Intro
01:06 How I went from 9 to 5 to doing a podcast in 18 months (The podcast origin story)
08:27 How you can go from 0-50k subscribers.
14:38 Was there ever a moment where I thought it wouldn't work, (I was broke & stressed!)19:17 Did we copy the DOAC?
22:36 How has life changed after getting views?2024-04-0131 min
CLOT ConversationsPharmacokinetics of DOACS after Bariatric Surgery - Gunka & MithoowaniSend us a textThis podcast episode features Dr. Barbara Gunka and Dr. Siraj Mithoowani discussing their research on how bariatric surgery affects direct oral anticoagulants (DOACs).Bariatric surgery is increasingly used to fight obesity-related health problems. However, these patients often need DOACs to prevent blood clots due to surgery and obesity.The concern is that bariatric surgery might change how the body absorbs DOACs. This could make the medications less effective. There's limited data on long-term DOAC use after bariatric surgery.Dr. Gunka and Dr...2024-03-2220 min
The Lead Podcast presented by Heart Rhythm SocietyThe Lead Podcast - Episode 54Deepthy Varghese, MSN, ACNP, FNP, Northside Hospital, is joined by Gregory Lip, MD., University of Liverpool, and Elaine Y. Wan, MD, FHRS Columbia University, Cardiology to discuss the limitations of current clinical decision tools for assessing bleeding risk in individuals with atrial fibrillation (AF) taking direct-acting oral anticoagulants (DOACs). Conducted as a secondary analysis of the RE-LY trial and validated in multiple cohorts, the study introduces the DOAC Score as a personalized risk assessment tool. The DOAC Score incorporates various covariates such as age, creatinine clearance, underweight status, medical history, and medication use to estimate the comparative risk for...2024-03-2121 min
UNBOXEDMeet Diary Of A CEO’s Secret WeaponThis week on Unboxed, we are joined by Grace Andrews, the Marketing Director for Steven Bartlett's personal brand and podcast, Diary of a CEO.
In this episode, Grace reveals:
Why 50% of the DOAC's guests cry
The tools the DOAC team uses to stand out
The secret to creating good content
The most common mistakes marketers make on social media
The importance of social proofing yourself
Time stamps:
0:00 - Intro
1:00 - How Grace Started at DOAC?
2:30 - Story of DOAC
3:55 - Biggest Mistakes?
9:55 - How to build...2024-01-1057 min
Cardionerds: A Cardiology Podcast353. Atrial Fibrillation: Anticoagulation Pharmacology & Clinical Decision-Making with Dr. Ashley Lochman and Dr. Chris DomenicoCardioNerds co-founder Dr. Amit Goyal, series co-chair Dr. Colin Blumenthal, and episode lead Dr. Anushka Tandon to discuss pharmacologic anticoagulation options in atrial fibrillation with Drs. Ashley Lochman and Chris Domenico. The case-based review helps clarify some key concepts, such as when warfarin is preferred for anticoagulation, who may be a good DOAC (direct-acting oral anticoagulant) candidate, how to choose an appropriate DOAC agent, and how to manage anticoagulation therapy in patients already on antiplatelet therapies. Notes were drafted by Dr. Anushka Tandon. The episode audio was edited by student Dr. Shivani Reddy.
This CardioNerds Atrial Fibrillation series is a...2023-12-291h 03The Diary Of A CEO with Steven BartlettThe Top 7 Belly Fat Burning Hacks For 2024 That Are PROVEN To Work!As a holiday wrap-up, we’ve listened to you and answered one of the most popular questions; What is your favourite EVER episode?But, we think the more important question is what is YOUR favourite episode on the Diary of CEO of all time. Using our in-house data scientist and a group of analysts, we’ve found the most replayed and shared moments from 2023. This should be the most valuable episode you will ever listen to.7th Most Replayed Moment, Dr. Giles Yeo.Dr Giles takes on some of the bigg...2023-12-261h 18
日経メディカル 聴く論文149.日経メディカル 聴く論文（2023.11.27-12.01） フレイル＋心房細動に処方しやすいDOACは？ 他2023年11月27日から12月1日に日経メディカル Onlineで紹介した5本の海外医学論文のエッセンスを日本語音声でお届けします。
①JAMA Network Open誌から フレイル＋心房細動に処方しやすいDOACは？
②BMJ誌から 帯状疱疹生ワクチンの有効性の持続期間は？
③JAMA Cardiology誌から ダパグリフロジン投与開始直後のeGFR低下は問題ない
④NEJM誌から ボツリヌス毒素は本態性頭部振戦にも有効
⑤NEJM誌から IgA腎症に対する新規抗体薬の第2相臨床試験2023-11-3010 min
NGMC Continuing Medical EducationGHI Grand Rounds: DOAC's and the New Factor XI Anti-thrombotic TherapiesTitle: Cardiology Grand Rounds: Lessons Learned from DOAC's and the New Factor XI Anti-thrombotic Therapies Being Studied
Speaker: Manesh R. Patel, MD
Chief, Division of Cardiology
Co-Director, Duke Heart Center
Duke Clinical Research Institute
Duke University, Durham, NC
Disclosures:
Research Grants: PACIFIC-AF: Bayer, Janssen, Heartflow, Idorsia, NHLBI, Novartis
Advisory Board/Consulting: Bayer, Janssen, Heartflow, Medscape
Objectives:
•Understand the Net-Benefit of Warfarin and then NOACs in AFib
•Understand the use of NOACs and limitations
•Understand the Factor XI therapy and promise in A. Fib2023-09-191h 05
Discussing essential topics related to Clinical Pharmacists in General PracticeConducting DOAC Reviews in Primary Care: What do you need to know?Conducting DOAC Reviews in Primary Care: What do you need to know?Join us for the latest episode of our new clinical series, where we dive into the topic of DOACs (Direct Oral Anticoagulants). In this episode, we discuss this topic with Angelina Soliman, a Senior IP Pharmacist who specialises in Atrial Fibrillation and Anticoagulation. Also adding to the conversation is my co-host, Ruhina Kassam, who is a Senior IP Pharmacist and the Training and Development Lead of Clinical Pharmacist Solutions.Together, we explore the benefits of switching your patients from Warfarin to DOACs and...2023-07-1917 min
NEUROPODSTAGIONE 3 EPISODIO 34 - Stroke on DOAC treat or threatPODCASTER SENIOR: Andrea Zini;PODCASTER JUNIOR: Gabriele Prandin;RAZIONALE: Gli anticoagulanti orali diretti (DOAC) contro il fattore Xa e IIa hanno rivoluzionato le terapie per i pazienti con disturbi trombo-embolici, in particolare il cardioembolismo da Fibrillazione atriale non valvolare. Questa classe di farmaci che comprende Apixaban, Rivaroxaban, Edoxaban e Dabigatran ha dimostrato la sua superiorità nel diminuire il rischio emorragico sistemico ed intracranico e la medesima efficacia nel prevenire eventi ischemici cerebrali se paragonati al warfarin, come confermato da una metanalisi di trial clinici randomizzati pubblicata su Circulation nel 2022 che includeva circa 71000 pazienti. La diffusione d...2023-06-1314 min
The Authentic Man Podcast with David ChambersWeekly Mini-Episode: My thoughts on Chris Williamson & Steven Bartlett’s DOAC episode about dating and how men can up-level their dating chancesIn this week's mini-episode, I talk about an episode of the DOAC where Chris Williamson & Steven Bartlett speak about many things, but I will focus on what they talk about and ways that men, in particular, can improve their dating chances and lives. Things I cover: 🔥 How men can up-level their dating lives 🔥 Women aren’t just looking for men with money and education. There is another huge thing they want 🔥 How to be more sexually confident 🔥 Where I think Chris Williamson is wrong 🔥 Why the episode makes y...2023-04-1626 minThe Diary Of A CEO with Steven BartlettThe No.1 Health Expert: The One Food (WE ALL EAT) That's Slowly Hurting Us!: Max LugavereMax Lugavere is a foremost expert on the brain and how we can get the best out of it. A New York Times and Wall Street Journal best-selling author, his books 'Genius Foods', 'Genius Life' and 'Genius Kitchen' have ushered in a new way of seeing how what we eat effects how effective our brain is. What few know about Max is that his best-selling books come from deeply heartfelt motivation, as he saw his mother lost to dementia.Ever since that terrible day he's had one focus and one focus only - what can people do...2023-02-201h 52
Questioning Medicine207. Medical Update-- DOAC, Warfarin, diabetes, venous thromboembolism, EMPA-KIDNEY, EmpagliflozinEfficacy and Safety of Intensive Versus Nonintensive Supplemental Insulin With a Basal-Bolus Insulin Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Clinical Study | Diabetes Care | American Diabetes Association (diabetesjournals.org) randomized noninferiority study from Emory University, 224 hospitalized patients with longstanding type 2 diabetes Both groups received basal/bolus insulin; both the starting dose and subsequent changes were specified by the study protocol. Additional premeal SSI was added to scheduled premeal bolus doses.randomized to either intensive SSI (at BG >140 mg/dL) or nonintensive SSI (at BG >260 mg/dL) before meals...2023-02-0917 min
Primary Care SpotlightAudit Tool for DOAC Prescribing in General PracticeIn this episode of primary care spotlight Emma speaks with pharmacist David Jenkins about an audit tool for DOAC prescribing in general practice. David is a Fellow of the Royal Pharmaceutical Society and a member of the South Kerrier Primary Care Network Pharmacy Team. The team were highly commended in the recent General Practice Awards, and in October won a prestigious national Health Services Journal Patient Safety Award for their project Audit Tool for DOAC Prescribing in General Practice. 2023-02-0617 min
BMJ talk medicineSwapping to edoxaban, DOACs in renal impairment, inflammatory rheumatic diseases in pregnancyIn this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the February 2023 issue of DTB. They discuss concerns over a national initiative in England to transfer people with atrial fibrillation to edoxaban from other DOACs (https://dtb.bmj.com/content/61/2/18). They review a study that examined whether the correct dose of DOAC was used in people with renal impairment (https://dtb.bmj.com/content/61/2/21). They talk about the use of empagliflozin in people with heart failure (https://dtb.bmj.com/content/61/2/22) and finish with an overview of an article that discusses prescribing for pregnancy for those with...2023-01-3125 minDTB PodcastSwapping to edoxaban, DOACs in renal impairment, inflammatory rheumatic diseases in pregnancyIn this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the February 2023 issue of DTB. They discuss concerns over a national initiative in England to transfer people with atrial fibrillation to edoxaban from other DOACs (https://dtb.bmj.com/content/61/2/18). They review a study that examined whether the correct dose of DOAC was used in people with renal impairment (https://dtb.bmj.com/content/61/2/21). They talk about the use of empagliflozin in people with heart failure (https://dtb.bmj.com/content/61/2/22) and finish with an overview of an article that discusses prescribing for pregnancy for those with...2023-01-2325 minThe Diary Of A CEO with Steven Bartlett5 Scientific Rules for Making & Breaking Habits!In this episode I wanted to do something that I haven't done in a while. It's been too long since it was just me, the microphone, and you. If there's one request I get over and over again, it's for more episodes of DOAC like in our early years, just me what's front of my mind - an authentic 'Diary of a CEO'.It's been an incredible 2022, our level of guest and conversation has only got higher and higher, but I wanted to look forward to 2023. Specifically, something that's been on my mind lately, how do you...2022-12-2957 min
Igreja do Amor#545 - TUDO REQUER DOAÇÃO - PR. ANDRÉ SIQUEIRA#545 - TUDO REQUER DOAÇÃO - PR. ANDRÉ SIQUEIRA by Igreja do Amor2022-10-3140 min
Heart to Heart NursesExploring the Relationship Between AFib and VTE: Identification and AwarenessAtrial Fibrillation (AFib) and Venous Thromboembolism (VTE) have a risky bidirectional relationship. Hear from Carol Patrick, RNFA, ACNP-BC, FPCNA, as she explores this relationship and the different management and prevention techniques. Learn also about how cancer can increase a patient's risk for AFib and VTE. PCNA AFib Resources: https://pcna.net/clinical-resources/provider-tools/atrial-fibrillation-provider-tools/ PCNA VTE Resources: https://pcna.net/clinical-resources/patient-handouts/vte-and-blood-clot-tools-and-handouts/Atherosclerosis Risk in Community (ARIC) Study: https://onlinelibrary.wiley.com/doi/10.1111/jth.13974Pulmonary Embolism and Atrial Fibrillation: Two Sides of the Same Coin? A Systematic Rev...2022-10-1827 min
ValveCastClick Valvar #361 - Uso dos DOAC’s em próteses mecânicasNo Click Valvar de hoje temos grandes insights sobre o uso dos DOAC’s em próteses mecânicas.2022-10-1303 min
DozeCast - Cardiologia055 - Um breve tutorial dos Anticoagulantes Orais Diretos (DOACs)Tem segurança na hora de prescrever os DOACs? Suas inidcações, contraindicações e situações especiais para o seu uso?
No episódio #55 do DozeCast, Manuela, Maria Júlia (proibido confundir as duas mais!!!) e Diandro discutem o universo dos DOACs e os principais estudos que validaram o seu uso nos mais diversos cenários clínicos.
E ainda alguns fun facts que aposto que vão te surpreender!
Minutagem:
(01:49): por que os DOACs surgiram
(06:42): RELY Trial - Dabigatrana
(08:12): ROCKET AF - Rivaroxabana
(08:51): ARISTOTLE - Apixabana
(09:22): ENGAGE AF - Edoxabana
(09:37): debate sobre o uso dos DOACs
(12:37): quando não usar
(13:58...2022-10-1333 min
Mayo Clinic Pharmacy Grand RoundsLevel Up: Updates on Direct Oral Anticoagulant Plasma LevelsNikitha Yagnala, PharmD (Twitter: @NikithaYagnala) describes laboratory tests used to estimate DOAC plasma levels, reviews current literature exploring the association between DOAC plasma levels and clinical outcomes and outlines appropriate utilization and interpretation of DOAC plasma levels in clinical practice.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
2022-09-2837 minValveCastClick Valvar #346 - Posologia dos DOAC’sNo Click Valvar de hoje vamos falar sobre a Posologia dos DOAC’s.2022-08-2203 min
Medical Digest & Congress ReportStrategies for Assessing and Managing DOAC-Related Bleeding - report from ISTH2022Professor Deborah Siegal chaired an interesting symposium during the ISTH 2022 congress in London, the topic was strategies for assessing and managing DOAC-related bleeding.
Video: https://congressreport.eu/scientific-contents/interview:strategies-assessing-and-managing-doac-related-bleeding2022-07-2610 minCLOT ConversationsNew GI Guidelines on Management of GI Bleeds with Alan Barkun & Jim DouketisSend us a textIn this episode we discuss a recent paper published jointly in The American Journal of Gastroenterology and the Journal of the Canadian Association of Gastroenterology entitled American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period and co-authored by a Canada – United States team of experts.The interview with co-authors Dr Alan Barkun and Dr Jim Douketis covers the rationale for the new guidelines as well as the implications for clinicians. Dr Barkun is Professor of Me...2022-06-1636 min
Emergency Medical MinutePodcast 789: DOACContributor: Aaron Lessen, MD Educational Pearls: Direct Oral Anticoagulants (DOACs) have surpassed Warfarin and Lovenox® for anticoagulation as they do not require injection and allow for easier discharge. In the ED, they are commonly prescribed after PE or DVT diagnosis. Common DOACs are Apixaban (Eliquis®) and Rivaroxaban (Xarelto®). There has not been a direct head to head study comparing outcomes. 2 large observational studies evaluated the recurrence of clots and bleeding risk in patients with newly prescribed Eliquis® or Xarelto® for DVT or PE. Both studies found that Eliquis® had superior outcomes. Further data is required to determine...2022-06-1303 min
CardioAulaTratando paciente com DOAC’s de forma eficaz e segura I PodCast CardioAula® #196Dr. Halsted Gomes disserta sobre o artigo Atlantis trial. O estudo explica se podemos utilizar DOAC’s após a TAVI e obter a mesma eficácia e segurança que a terapia padrão.2022-05-0709 min
The Curbsiders Internal Medicine Podcast#333 Prescribing pearls, Periop Medicine, PMR, Gout, OSA, Nocturia, Food as Medicine, a new Obesity paradigm, and rethinking Afib! ACP #IM2022 HighlightsWe recap the top pearls from ACP #IM2022 including important drug interactions/intolerance (acetaminophen, tramadol, ticagrelor, nirmatrelvir-ritonavir), perioperative medicine (bridging, DOAC reversal agents, dental procedures, MINS), recognizing PMR, when to initiate urate-lowering therapy in gout, glucocorticoid-induced osteoporosis, food as medicine, dietary potassium, OSA, nocturia, telemedicine and health equity, a new obesity medicine paradigm, advances in HIV/PrEP, and rethinking atrial fibrillation!
Note: Due to a rapid turnaround there is no CME for this episode, but visit curbsiders.vcuhealth.org to claim credit for past episodes.
Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME!
2022-05-061h 01The Curbsiders Internal Medicine Podcast#333 Prescribing pearls, Periop Medicine, PMR, Gout, OSA, Nocturia, Food as Medicine, a new Obesity paradigm, and rethinking Afib! ACP #IM2022 HighlightsWe recap the top pearls from ACP #IM2022 including important drug interactions/intolerance (acetaminophen, tramadol, ticagrelor, nirmatrelvir-ritonavir), perioperative medicine (bridging, DOAC reversal agents, dental procedures, MINS), recognizing PMR, when to initiate urate-lowering therapy in gout, glucocorticoid-induced osteoporosis, food as medicine, dietary potassium, OSA, nocturia, telemedicine and health equity, a new obesity medicine paradigm, advances in HIV/PrEP, and rethinking atrial fibrillation!
Note: Due to a rapid turnaround there is no CME for this episode, but visit curbsiders.vcuhealth.org to claim credit for past episodes.
Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME!
2022-05-061h 01Questioning Medicine195. Medical Update-- GERD guidelines, IV iron, bariatric surgery, DOAC and the Frail PmtsEuropean Heart JournalBariatric surgery and cardiovascular disease: a systematic review and meta-analysisEur Heart J 2022 Mar 04;[EPub Ahead of Print], SL van Veldhuisen, TM Gorter, G van Woerden, RA de Boer, M Rienstra, EJ Hazebroek, DJ van Veldhuisen 39 studies, all prospective or retrospective cohort studies, showed Bariatric surgery is associated with a reduced hazard ratio (HR) of CV morality (0.59), all-cause mortality (0.55), incident HF (0.50), myocardial infarction (0.58) and stroke (0.64) Authors state “”The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced...2022-05-0525 minValveCastClick Valvar#314 - DOAC's na Estenose MitralNo Click Valvar de hoje, temos insights sobre um aspecto interessante sobre o uso dos DOAC's na Estenose Mitral!2022-05-0202 minCLOT ConversationsAnti-seizure & Anticoagulant medications & interactionsSend us a textThis is Episode 4 of CLOT Conversations from Thrombosis Canada. In this episode Dr Jameel Abdulrehman and David Airdrie are joined by Dr Vinai Bhagirath and Dr Sam Schulman, two of the authors of a recently published paper entitled Carbamazepine, phenytoin, and oral anticoagulants: Drug-drug interaction and clinical events in a retrospective cohort. The paper was published in Research and Practice in Thrombosis and Haemostasis (Res Pract Thromb Haemost. 2022;6:e12650. https://doi.org/10.1002/rth2.12650)The authors discuss the results of the retrospective cohort of patients taking carbamazepine or phenytoin with warfarin or...2022-04-2130 minValveCastClick Valvar#310 - Uso dos DOAC's nas ValvopatiasNo Click Valvar de hoje, temos insights sobre um aspecto interessante, os aspectos clínicos relevantes sobre o uso dos DOAC's nas valvopatias!2022-04-1805 min
This Week in CardiologyJan 14, 2022 This Week in Cardiology PodcastXeno-transplantation, weight loss drugs, DOAC coverage, vitamin D, LAAC and frailty, and recalled LVADs are the topics John Mandrola, MD, discusses in this week’s podcast. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I – Xenotransplantation - Pig Heart Successfully Transplanted to Man https://www.medscape.com/viewarticle/966367 - What Does a Pig-to-Human Heart Transplant Mean for Medicine? https://www.medscape.com/viewarticle/966488 II – Weight Loss Drugs - Wegovy Tops Sibling Saxenda for Weight Loss https://www.medscape.com/viewarticle/966376 - Effect...2022-01-1416 minThis Week in CardiologyJan 7, 2022 This Week in Cardiology PodcastCauses of sudden death, inclisiran, DOAC choices, and alcohol and VT/VF are the topics discussed by John Mandrola, MD, in this week’s podcast. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I – Causes of Sudden Death - Cardiac Device Interrogation After Death 'Richly Informative' https://www.medscape.com/viewarticle/965730 - Postmortem Interrogation of Cardiac Implantable Electronic Devices: A 15-Year Experience https://www.jacc.org/doi/full/10.1016/j.jacep.2021.10.011 - Sudden Death in Patients With Cardiac Implantable Electronic Devices https://pubmed.ncbi.nlm...2022-01-0720 minThis Week in CardiologyOct 22, 2021 This Week in Cardiology PodcastAspirin for primary prevention, induced hypothermia, half-dose DOAC, and social media, are the topics John Mandrola, MD, discusses in this week’s podcast. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I - ASA for Primary Prevention - USPSTF Rules Out Aspirin for Over 60s in Primary CVD Prevention https://www.medscape.com/viewarticle/960745 - Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication https://www.uspreventiveservicestaskforce.org/uspstf/document/draft-evidence-review/aspirin-use-to-prevent-cardiovascular-disease-preventive-medication - Use of aspirin to reduce risk of initial vascular events in patients at mo...2021-10-2224 min
House of GodCastAflevering 2 - AntistollingEr is bijna geen afdeling in het ziekenhuis waar je niet te maken krijgt met antistolling. Belangrijk dus voor elke dokter om goed op de hoogte te zijn van de indicaties en de gevaren. Helaas is het in het begin vaak een wirwar van stofnamen, merknamen, indicaties en terminologie.In deze aflevering van de House of GodCast proberen we wat orde in deze chaos te scheppen en brengen we je de belangrijkste indicaties voor antistolling bij. Ook bespreken we de belangrijkste soorten bloedverdunners en hun voor- en nadelen. Uiteraard doen we dat ook dit keer weer door informatie t...2021-07-2636 min
Questioning Medicine174. Gestational Diabetes Screening, DOAC for Valvular Afib, COVID19, SemaglutideDOAC are just as safe if not safer for warfarin for valvular afib (NOT valve replacement but moderate to severe mitral stenosis). Please, just give normal lovenox for covid patients. Stop DM drugs in the elderly cause no-glycemia is more dangerous than hyperglycemia. semaglutide works as along as you keep taking it. gestational diabetes screening should be a two stop process. Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation: A Population-Based Cohort Study: Annals of Internal Medicine: Vol 0, No 0 (acpjournals.org) researchers did a New-user retrospective...2021-04-0421 min
ACEP Frontline - Emergency MedicineDOAC Reversal in the ED with Drs. Colin Kaide and Eric CucchiIn this week’s episode, we’re joined by Colin Kaide, MD, an Emergency Physician with Wexner Medical Center at The Ohio State University, and Eric W. Cucchi MS, PA-C, is the Director of Operations, eICU Support Center at UMass Memorial Medical Center. With stroke being one of the top 3 causes of death in the nation, timing is everything! Join the conversation to listen as they share insights into the rapid reversal of DOAC-associated bleeding and practical strategies for aligning clinical practice with local hospital bleeding management protocols.
Support for this episode provided through a grant from Spire Learning.2021-02-1537 min
Circulation: Arrhythmia and Electrophysiology On the BeatCirculation: Arrhythmia and Electrophysiology September 2020 IssuePaul J. Wang: Welcome to the monthly podcast, On the Beat for Circulation: Arrhythmia and Electrophysiology. I'm Dr. Paul Wang, Editor-in-chief, with some of the key highlights from this month's issue. In our first paper, Zak Loring and associates examined 3,139 patients undergoing atrial fibrillation (AF) ablation, between 2016 and 2018 in the Get With The Guidelines-Atrial Fibrillation Registry from 24 US centers. Patients undergoing AF ablation were predominantly male (63.9%) and Caucasian (93.2%) with a median age of 65. Hypertension was the most common comorbidity (67.6%), and persistent atrial fibrillation patients had more comorbidities than paroxysmal AF patients. Drug refractory, paroxysmal AF...2021-01-1234 min
PERTcastDedicated DOAC Trials for the Treatment of Pulmonary Embolism: Part 3The PERT Consortium invites you to listen to a podcast moderated by past immediate president of PERT Consortium Victor Tapson, MD, and joined by Alex Spyropoulos, MD, as they discuss extension of VTE treatment with a DOAC to reduce the risk of recurrence and the 2019 ESC Guidelines on extension of treatment.2020-09-2400 min
PERTcastDedicated DOAC Trials for the Treatment of Pulmonary Embolism: Part 1The PERT Consortium invites you to listen to a podcast moderated by past immediate president of PERT Consortium Victor Tapson, MD, and joined by Alex Spyropoulos, MD, as they discuss dedicated DOAC trials that evaluated the treatment of pulmonary embolism. 2020-09-0800 min
ドクターサロン「ワルファリンとDOAC」（2020813放送）「ワルファリンとDOAC」について、（解 説）聖路加国際病院心臓血管外科医長 阿部恒平氏（ききて）葵会柏たなか病院糖尿病センター長 山内俊一氏2020-08-2000 min
OncoPharmCaravaggioReviewing the lasted DOAC study in treating cancer-associated VTE: Caravaggio. We compare it the other major DOAC studies in this patient population. Caravaggio: https://www.nejm.org/doi/full/10.1056/NEJMoa1915103
Also, announcing our first journal club! This will be our 4/16 Pod. It is especially for an oncology APPE students missing out on an oncology experience, but all are welcome to participate. Journal Club link: https://www.futuremedicine.com/doi/pdf/10.2217/fon-2018-07872020-04-0215 min
FarmacologiaDOAc: introduzione.#salute #anatomia #esameobiettivo #farmaci #farmacologia #fisiologia #infermieri #medici #medicina #semeiotica #terapia #studenti #rianimazione #emergenze #urgenze #cuore #fibrillazione #dabigatrna #apixaban #rivaroxaban #edoxaban #anticoagulanti #coagulazione #emorragia #trombosi #embolia #tromboembolismoBenvenuti nel canale di podcast della serie “pillole di medicina”. Questo progetto audio ha finalità puramente didattiche e divulgative ed è indirizzato a giovani apprendisti del settore sanitario quale supporto per lo studio e l'approfondimento personale in relazione a tematiche generali di medicina e semeiotica clinica.L'iniziativa è parte integrante dei progetti formativi della Società Scientifica di Medicina Diagnostica e Terapeutica (SIMEDET), società multidisciplinare dedicata a studenti di medicina, infermieri, medici specialisti e non. Il p...2020-01-3008 min
Pharmacy to Dose: The Critical Care PodcastPCCs for PharmDsProthrombin Complex Concentrates (PCCs) for PharmDs
Special Guest: Scott Dietrich, PharmD, BCCCP
Show Notes: https://pharmacytodose.files.wordpress.com/2019/12/pccs-for-pharmds-show-notes.pdf
Show References: https://pharmacytodose.files.wordpress.com/2019/12/pccs-for-pharmds-references.pdf
3:05 – Anticoagulation reversal pre-PCC
5:18 – Brief history of PCC
6:45 – Current role for 3-factor PCC
7:56 – When should we be using PCC?
10:00 – Role of PCC for non-reversal indications
13:20 – Weight-based v. Fixed-dose Kcentra
15:39 – Why fixed-dose Kcentra?
17:33 – When to re-dose Kcentra?
18:50 – Kcentra when INR < >
PharmacyToDose.Com
@PharmacyToDose on Twitter/Instagram
PharmacyToDose@Gmail.com
Learn more about your ad choices. Visit megaphone.fm/adchoices2019-12-0553 min
Blood Advances TalksManaging patients who are receiving warfarin (or DOAC)and need an elective surgery or procedureManaging patients who are receiving warfarin (or DOAC)and need an elective surgery or procedure by Blood Advances Talks2019-06-2521 min
MDedge CardiocastStroke risk, DOAC type in nonvalvular A-Fib patientsThis week's top stories in clinical medicine: Single-center study outlines stoke risk, DOAC type in nonvalvular A-fib patients ACOG guidance addresses cardiac contributors to maternal mortality Higher serum leptin levels associated with PAD Employed physicians now outnumber independent doctors 2019-05-1007 min
CorConsult Rx: Evidence-Based Medicine and PharmacyThe DOAC Reversal Controversy ft Dr. Brian GilbertOn this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We recently had a paper publish in the American Journal of Emergency Medicine (Dr. Gilbert was the lead author). The name of the article and link can be found below: Throwing it in reverse: An update...2019-04-1252 minCorConsult Rx: Evidence-Based Medicine and PharmacyThe DOAC Reversal Controversy ft Dr. Brian GilbertOn this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We recently had a paper publish in the American Journal of Emergency Medicine (Dr. Gilbert was the lead author). The name of the article and link can be found below: Throwing it in reverse: An update...2019-04-1252 min
CorConsult Rx: Evidence-Based Medicine and PharmacyThe DOAC Reversal Controversy ft Dr. Brian GilbertOn this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We recently had a paper publish in the American Journal of Emergency Medicine (Dr. Gilbert was the lead author). The name of the article and link can be found below: Throwing...2019-04-1252 min
DTB podcastApril 2019: DOAC dosing in renal impairmentIn April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the challenges of prescribing direct acting oral anticoagulant (DOAC) drugs for people with renal impairment. The editors also talk about the use of saline nasal irrigation and discuss central sensitisation syndrome.
Read the issue online: https://dtb.bmj.com/content/57/4.2019-03-2710 minDTB PodcastApril 2019: DOAC dosing in renal impairmentIn April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the challenges of prescribing direct acting oral anticoagulant (DOAC) drugs for people with renal impairment. The editors also talk about the use of saline nasal irrigation and discuss central sensitisation syndrome.
Read the issue online: https://dtb.bmj.com/content/57/4.
2019-03-2010 min
Circulation on the RunCirculation February 5, 2019 IssueDr Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr Carolyn Lam, from National Heart Center and Duke National University of Singapore. Dr Greg Hundley: And I'm Greg Hundley, associate editor for circulation from VCU Health Systems in Richmond, Virginia. Dr Carolyn Lam: What does cardiac autoimmunity, glycemic control, and cardiovascular disease risk and Type I diabetes have in common? Well, you've got to wait for our feature discussion. This one's such a hot one, don't you agree, Greg? We could hardly finish talking. Dr Greg Hund...2019-02-0400 min
The Curbsiders Internal Medicine Podcast#128 Aspirin Overhyped and OverusedAspirin’ to figure out if ASA can help prevent a heart attack? Interpreting all the new trials doesn’t have to cause chest pain! Join Dr. Ambarish Pandey from UT Southwestern as he helps The Curbsiders ASCEND the mountains of the latest studies to ARRIVE at some well-informed conclusions on the role of aspirin in primary prevention for cardiac events. The team also discusses secondary prevention, aspirin and dual (or triple) antiplatelet therapy, and whether it’s okay to stop giving aspirin to older adults without known CAD (Spoiler alert: it’s okay). ACP members can visit https://acponline.org/curbs...2018-12-0353 minThe Curbsiders Internal Medicine Podcast#128 Aspirin Overhyped and OverusedAspirin’ to figure out if ASA can help prevent a heart attack? Interpreting all the new trials doesn’t have to cause chest pain! Join Dr. Ambarish Pandey from UT Southwestern as he helps The Curbsiders ASCEND the mountains of the latest studies to ARRIVE at some well-informed conclusions on the role of aspirin in primary prevention for cardiac events. The team also discusses secondary prevention, aspirin and dual (or triple) antiplatelet therapy, and whether it’s okay to stop giving aspirin to older adults without known CAD (Spoiler alert: it’s okay). ACP members can visit https://acponline.org/curbs...2018-12-0353 min
Coda ChangeIntracranial Haemorrhage and Anticoagulants in Critical CareJordan Bonomo delivers the run down on intracranial haemorrhage and anticoagulants in critical care. Jordan freely admits – this is not a simple topic. For the simple reason that intracranial haemorrhage (ICH) sucks – and that’s a problem. There are no treatments for it. Nothing seems to work. Add an anticoagulant and it is even worse. The mortality for an ICH is around 30-50%. With an anticoagulant onboard it goes up to 40-65%. So how do you manage an ICH in an anti-coagulated patient? The critical care starts in the Emergency Department. Roughly speaking 30% of intracerebral haemorrhages will increase in size b...2018-10-3017 min
Emergency Medicine CasesEpisode 89 – DOACs Part 2: Bleeding and Reversal AgentsIn this Part 2, DOACs Bleeding and Reversal we discuss the management of bleeding in patients taking DOACs with minor risk bleeds, like epistaxis where local control is easy to access, moderate risk bleeds, like stable GI bleeds and high risk bleeds, like intracranial hemorrhage. We answer questions such as: How do we weigh the risks and benefits of stopping the DOAC? When is reversal of the DOAC is advised? How best do we accomplish the reversal of DOACs? Is there any good evidence for the newest reversal agent? When should we stop DOACs for different procedures, and when should we...2016-12-0653 min
SCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.2016-12-0130 minSCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.2016-12-0130 minSCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.2016-12-0130 minSCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.2016-12-0130 minSCCM PodcastSCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future ApproachesTodd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz is Senior Staff Hospitalist and Medical Director for Professional Development and Research in the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan.2016-12-0130 min