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Declan Murphy & European Urology Family

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European Urology PodcastEuropean Urology PodcastMay 2025 | European Urology PodcastMore great highlights from the latest edition of European Urology! Here on the European Urology Podcast we bring you selected highlights from the journal each month with some great guests. As ever we highlight two key papers (details below) from this month's journal, including interviews with key authors. With co-Hosts Professor Declan Murphy (Melbourne, Australia), and Dr Nikita Bhatt (Newcastle, UK). We also catch up with one of our recent Award Winners, Dr Laura Elst (Leuven, BEL), who who won the Best Translational Paper Award 2024. Even better on our YouTube channelPodcast Priority Papers2025-05-0639 minGU Cast | Urology PodcastGU Cast | Urology PodcastIs there a Doctor on board??!A bit of a break from the usual GU Oncology routine today folks! Declan was back at Guy's Hospital recently doing a talk and heard a remarkable story told by one of the Urology Fellows, Dr Joachim Jimie. A quite spectacular mid-air crisis, and some great life lessons in there also.Declan could not resist the opportunity to grab Jimie and tell the tale again for GU Cast. Enjoy!!!Even better on our YouTube channel 2025-05-0125 minEuropean Urology PodcastEuropean Urology PodcastApril 2025 | European Urology PodcastMore great highlights from the latest edition of European Urology! Here on the European Urology Podcast we bring you selected highlights from the journal each month with some great guests. As ever we highlight two key papers (details below) from this month's journal, including interviews with key authors. With co-Hosts Professor Declan Murphy (Melbourne, Australia), and Dr Nikita Bhatt (Newcastle, UK). Editor-in-Chief Professor Alberto Briganti (Milano, ITA) also catches up with recent Impact Award Winner, Dr Riccardo Mastroianni (Rome, ITA)Even better on our Youtube channel Podcast Priority Papers1 . Robot-assisted Kidney Transplantation: The 8...2025-04-1046 minGU Cast | Urology PodcastGU Cast | Urology PodcastThe end of the road for TRUS biopsy? Translate trial reads outWe are delighted to drop this pod just as the landmark TRANSLATE trial reads out at the EAU Annual Meeting in Madrid, with a simultaneous publication in Lancet Oncology. This is the world's largest trial of transrectal vs transperineal (TP) prostate biopsy, and reports that TP biopsy has superior cancer detection ability. Is this the end of the road for TRUS biopsy. Hosts Declan Murphy and Renu Eapen are delighted to welcome first and senior authors, Prof Richard Bryant and Dr Alastair Lamb of the University of Oxford to have a detailed discussion about TRANSLATE and what this...2025-03-2340 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast in Shanghai | Prostate Cancer in China in 2025Declan Murphy is in the GU Cast studio in Shanghai with GU Cast China Editor, Prof Yao Zhu. We sit down with Prof Hao Zeng (West China Hospital) and Dr Ye Yan to discuss their experiences and perspectives on advancements in diagnostics like MRI and PSMA PET, the increasing use of Chinese-developed robotic surgery platforms, and the ongoing debate surrounding pelvic lymph node dissection. They also address the application of systemic therapies for metastatic disease, considering the unique characteristics of the Chinese patient population and the potential for dose adjustments. Today's pod also highlights the growing importance of precision...2025-03-1932 minGU Cast | Urology PodcastGU Cast | Urology PodcastBiochemical recurrence | With Steve FreedlandA fantastic episode for urologists, radiation oncologists, and anyone interested in localised prostate cancer. Biochemical recurrence (BCR) is unfortunately all too common after surgery or radiation for prostate cancer, and today we talk with someone who has been working in BCR for more than 20 years. Dr Steve Freedland, Urologist at Cedars-Sinai in Los Angeles, popped into the GU Cast studio to talk about the landmark series from Johns-Hopkins Medical Institute (links below) which still today remains our best guide to the natural history of BCR after radical prostatectomy. And the key message that PSA doubling time is our most...2025-03-0641 minGU Cast | Urology PodcastGU Cast | Urology PodcastENZA-P Big news Update: LuPSMA and enza improves overall survivalA breaking news podcast from ASCO GU in San Francisco! Prof Louise Emmett (St Vincent's, Sydney), has just read out the latest update from the ENZA-P trial (and simultaneous publication in Lancet Oncology), reporting that the combination of LuPSMA and enzalutamide improves overall survival when compared with enzalutamide alone, in men with poor prognosis mCRPC. Big news!! A 45% reduction in the risk of death in favour of the combination. Plus excellent quality of life for those receiving the combo. We are joined by Louise and co-author A/Prof Andrew Weickhardt (Austin Health, Melbourne), to discuss this exciting data...2025-02-1329 minGU Cast | Urology PodcastGU Cast | Urology PodcastFuture-gazing radioligand therapy in prostate cancer | With Oliver Sartor and Michael HofmanLook who popped into the GU Cast studio this week for a chat about where we are going next with radioligand therapy (RLT) for prostate cancer! Professors Oliver Sartor (Mayo Clinic, Rochester) and Michael Hofman (Peter Mac, Melbourne), are two of the world's most pre-eminent experts in the world of RLT for prostate cancer. They were each respectively PIs  on the VISION and TheraP RCTs published in NEJM and Lancet in 2021, and both have many ongoing trials in RLT for prostate cancer. We hear in which stages of prostate cancer LuPSMA is next likely to be approved, and so...2025-02-0237 minGU Cast | Urology PodcastGU Cast | Urology PodcastShanghai GU Oncology Highlights Part 2Part 2 of our GU Cast Conference Highlights from Shanghai including discussions with Dr Stephen Freedland (Los Angeles), Dr Liang Liang (Shaanxi), Dr Andrea Necchi (Milano), Dr Xiaojie Bian (Shanghai), and Dr Hongkai Wang (Shanghai).  Declan Murphy travelled to Shanghai for the 14th GU Oncology Academic Meeting hosted by Fudan University Shanghai Cancer Centre, and to meet up with our GU Cast China Editor, Dr Yao Zhu. This is an excellent meeting in one of our very favourite cities. In Part 1 we spoke to Conference Chair, Dr Dingwei Ye, Dr Karim Fizazi, Dr Peng Wu, and Dr Axel Merseburger, to o...2025-01-0940 minGU Cast | Urology PodcastGU Cast | Urology PodcastShanghai GU Oncology Highlights Part 1Declan Murphy travels to Shanghai for the 14th GU Oncology Academic Meeting hosted by Fudan University Shanghai Cancer Centre, and to meet up with our GU Cast China Editor, Dr Yao Zhu. This is an excellent meeting in one of our very favourite cities, and this year Declan joins International Faculty including Dr Stephen Freedland (Los Angeles), Dr Karim Fizazi (Paris), Dr Axel Merseburger (Lubeck). and Dr Andrea Necchi (Milano) to overview the latest stories in GU Oncology. Top Chinese experts from across the country also join and the meeting includes some landmark consensus statements from multidisciplinary panels....2025-01-0435 minGU Cast | Urology PodcastGU Cast | Urology PodcastStories of single-port surgery (and cricket)Our final episode of the year! And we end with a very seasonal celebration of single-port surgery and the Boxing Day Test with Australia playing India in one of the world's most famous cricket matches. We coaxed Dr Mihir Desai (University of Southern California, Los Angeles) and A/Prof Daniel Moon (Peter Mac, Melbourne) out of the Melbourne Cricket Ground and into our nearby studio at the close of play on Day 2 to talk all things single-port surgery (and cricket). Cricket-mad Mihir flew in from LA to tick off his bucket list ambition of attending a Boxing Day Test...2024-12-2833 minGU Cast | Urology PodcastGU Cast | Urology PodcastA Dummy's Guide to Metastatic Renal Cancer!!Have you ever found the choice of agents in metastatic kidney cancer just a bit perplexing??! Well then this is the podcast for you! To celebrate a fantastic review paper recently published in European Urology, we chat with first author Dr Regina Barragan-Carillo (City of Hope, California), and second senior author Dr Tian Zhang (UT South-Western, Texas). The title of the paper is "First and Second-line Treatments in Metastatic Renal Cell Carcinoma", and it's about the best paper we have read on this topic, with a proper who's who in renal cancer contributing. Plus completely up to date with...2024-12-0537 minGU Cast | Urology PodcastGU Cast | Urology PodcastThe Sir Chris Hoy Effect | Why family history mattersLegendary British cyclist Sir Chris Hoy (48) recently shocked the world by announcing that he has progressive metastatic prostate cancer. His specialists have given him a 2-4 year life expectancy. The dreadful news that no prostate cancer patient wants to hear. Today, hosts Prof Declan Murphy and Dr Renu Eapen welcome their good mates A/Prof Ben Challacombe (Guy's Hospital, London), and A/Prof Daniel Moon (Peter MacCallum Cancer Centre, Melbourne) to the GU Cast studio, and patient advocate Andrei Norris who joins on Zoom to discuss the huge publicity this has generated, and the importance of family history...2024-11-2429 minGU Cast | Urology PodcastGU Cast | Urology PodcastPLND, ARPI Switch & De-Escalation | PROSPECT Podcast part 2Part 2 Highlights from a GU Cast Live Event! Dr Kim Chi (Medical Oncologist, Vancouver) and Dr Carmen Mir (Urologist, Valencia) joined the PROSPECT meeting in Melbourne to discuss high-risk prostate cancer and mHSPC, along with many experts from around Australia. On the eve of the meeting over dinner, Declan Murphy led a GU Cast-themed panel discussion on five hot topics in prostate cancer, featuring snippets from GU Cast over the past few months.Part 2 today features controversies in PLND, the somewhat notorious ARPI switch control arm beloved of mCRPC trials, and teh importnt topic of de-escalation in advanced prostate...2024-11-1737 minGU Cast | Urology PodcastGU Cast | Urology PodcastPSMA Conundrums & Triplet vs Doublet | PROSPECT Podcast part 1Highlights from a GU Cast Live Event! Dr Kim Chi (Medical Oncologist, Vancouver) and Dr Carmen Mir (Urologist, Valencia) joined the PROSPECT meeting in Melbourne to discuss high-risk prostate cancer and mHSPC, along with many experts from around Australia. On the eve of the meeting over dinner, Declan Murphy led a GU Cast-themed panel discussion on five hot topics in prostate cancer, featuring snippets from GU Cast over the past few months. Part 1 today features PSMA conundrums and triplet vs doublet therapy. Even better on our YouTube channel This is a Themed Podcast supported by...2024-11-0347 minGU Cast | Urology PodcastGU Cast | Urology PodcastTreatment intensification in mHSPC | The Who, When, and How? Live webinar replayA GU Cast Live Event!! Everything you need to know about treatment intensification in mHSPC!! Doublet vs Triplet. Who should have radiotherapy? PSMA PET/CT conundrums, e-escalation, case discussions and more. Featuring GU Cast Hosts Declan Murphy and Renu Eapen, Medical Oncologist Ben Tran, Nuclear Medicine Physician Louise Emmett, and Radiation Oncologist Amy Hayden. Plus lots of interaction from our live audience around Australia.Watch the full webinar including presentations on our YouTube channelThis GU Cast Live Event was an interactive educational webinar supported by our Gold Partners, Mundipharma.Learning objectives: 2024-10-291h 32European Urology PodcastEuropean Urology PodcastFebruary 2024 | European Urology HighlightsA great mixture on the European Urology Podcast this month with AI and  bladder cancer featuring in our highlight papers (details below). Co-hosts Declan Murphy and Joyce Baard bring you interviews with key authors and expert commentators, and we also look at other highlights with guest contributor Dr Fabian Stangl (Bern, Switzerland). Plus, Laura stays on for a chat about her role as one of our new Associate Editors at European Urology, a bit about her career, and an update on her personal links to the war in Ukraine. Even better on our YouTube channel P...2024-02-1157 minEuropean Urology PodcastEuropean Urology PodcastJanuary 2024 | European Urology HighlightsWe celebrate the start of 2024 with a cracking podcast to showcase the January edition of European Urology!! Co-hosts Declan Murphy and Joyce Baard highlight two key papers (details below) from this month's journal, including interviews with key authors and expert commentators. We also look at other highlights in this month's journal with guest contributor Dr Stefani Croghan (Dublin).  Even better on our YouTube channelPodcast Priority Papers1. European Association of Nuclear Medicine Focus 5: Consensus on Molecular Imaging and Theranostics in Prostate CancerFeatured author - Dr Daniela Oprea-Lager (Amsterdam U...2024-01-0448 minEuropean Urology PodcastEuropean Urology PodcastDecember 2023 | European Urology HighlightsMore great highlights from the latest edition of European Urology!! Here on the European Urology Podcast we bring you selected highlights each month with some great guests. As ever we highlight two key papers (details below) from this month's journal, including interviews with key authors and expert commentators. We also look at other highlights in this month's journal with guest contributor Dr Bernard Jansen (Amsterdam).  Declan Murphy hosting on his own this week as co-Host Joyce Baard couldn't make it. But Joyce will be back for our first podcast in 2024!!Even better on our YouTube channel2023-12-0136 minGU Cast | Urology PodcastGU Cast | Urology PodcastLymph node recurrence - what to do and when??! With Piet Ost, Shankar Siva and Michael HofmanSABR supremos Piet Ost and Shankar Siva join us to discuss the management of lymph node-only recurrence following primary treatment of prostate cancer. And of course our resident PSMA PET/CT guru Michael Hofman also turned up as himself and Piet love debating the merits of PSMA!How and when shoudl we image for biochemical recurrence? What are the limits of SABR? WHat about systemic therapy? It's all in this episode with great leaders in the field.Recorded on site at Peter Mac on the fringe of the 2023 SABR Symposium. With your usual hosts Renu Eapen and...2023-11-2530 minGU Cast | Urology PodcastGU Cast | Urology PodcastnmCRPC made easy!! Who, when and howProf Fred Saad (University of Montreal) drops in to chat about the interesting condition that is non-metastatic castration-resistant prostate cancer (nmCRPC). Which men are at risk of developing metastases? When should we use an AR pathway inhibitor? Why PSMA PET/CT should NOT be used. And hear his thoughts on "dabbling" in prostate cancer! Also joined by Professor Shankar Siva and Dr Louise Kostos from Peter MacCallum Cancer Centre. Hosted as ever by Dr Renu Eapen and Professor Declan Murphy. Fred was on a speaker tour in Australia supported by Bayer Pharmaceuticals and this Themed Podcast is...2023-11-1837 minEuropean Urology PodcastEuropean Urology PodcastNovember 2023 | European Urology HighlightsThe November 2023 edition of European Urology is full of fantastic content! Here on the European Urology Podcast we bring you selected highlights to whet your appetite. Co-hosts Professor Declan Murphy (Melbourne) and Dr Joyce Baard (Amsterdam) highlight two key papers (details below) from this month's journal, including interviews with key authors and expert commentators. We also look at other highlights in this month's journal with Dr Nikita Bhatt. Plus, in our “Meet the Editor” segment, we chat with Dr Maarten Albersen, Urologist at the University of Leuven and Associate Editor of European Urology. Even better on our YouT...2023-11-091h 05European Urology PodcastEuropean Urology PodcastOctober 2023 | European Urology highlightsAnother huge month in European Urology and we bring you selected highlights here on the European Urology podcast. Co-hosts Professor Declan Murphy (Melbourne) and Dr Joyce Baard (Amsterdam) highlight two key papers (details below) from this month's journal, including interviews with key authors and expert commentators. We also look at other highlights in this month's journal with Dr Nikita Bhatt. Plus Declan was in Milan recently and sat down with current and past Editors-in-Chief, Professor Alberto Briganti and Professor Francesco Montorsi to have a chat. Even better on our YouTube channelPodcast Priority Papers1...2023-10-081h 01European Urology PodcastEuropean Urology PodcastSeptember 2023 European Urology highlightsThe inaugural episode of the European Urology podcast is here! Co-hosts Professor Declan Murphy (Melbourne) and Dr Joyce Baard (Amsterdam) highlight two key papers (details below) from this month's journal, including interviews with key authors and other experts. We also look at other highlights in this month's journal with Dr Nikita Bhatt. Plus an interview with new Editor-in-Chief, Professor Alberto Briganti. Even better on our YouTube channelPodcast Priority Papers1. Phase 2 Trial of Stereotactic Ablative Radiotherapy for Patients with Primary Renal Cancer https://www.europeanurology.com/article/S0302-2838(23)02625-8/fulltextFeatured author...2023-09-0141 minGU Cast | Urology PodcastGU Cast | Urology PodcastThe European Urology Podcast is coming soon!!Here's a quick plug for another podcast that GU Cast is very happy to support!Launching in September 2023, the European Urology Podcast is a new monthly podcast to accompany the world's highest ranked urology journal, European Urology. Co-hosted by Professor Declan Murphy in Melbourne and Dr Joyce Baard in Amsterdam, the European Urology Podcast will highlight key papers and feature interviews with authors, editors and special guests. It will be produced by the team behind GU Cast. Learn more in this short trailer and subscribe on your favourite podcast platform to get the latest content. Just search...2023-08-1903 minEuropean Urology PodcastEuropean Urology PodcastThe European Urology Podcast is coming soon!!Launching in September 2023, the European Urology Podcast is a new monthly podcast to accompany the world's highest ranked urology journal, European Urology. Co-hosted by Professor Declan Murphy in Melbourne and Dr Joyce Baard in Amsterdam, the European Urology Podcast will highlight key papers and feature interviews with authors, editors and special guests. It will be produced by the team behind GU Cast. Learn more in this short trailer and subscribe to get the latest content!2023-08-1903 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast hosts do battle at ANZUP ASM!!Declan and Renu as you haven't seen them before! They leave their cosy  podcast studio to do battle at the Australia & New Zealand Urogenital & Prostate Trials Group (ANZUP) Annual Scientific Meeting! The battleground is renal cancer, with Renu arguing in favour of adjuvant immunotherapy, and Declan arguing against. No holds barred. Who wins??! Tune in to find out.Plus we chat with some of the ANZUP ASM international faculty including Alex Wyatt, Lauren Buffart, Ananya Choudhury, Andrea Apolo and Darren Feldman. Congratulations to ASM Convenors Ben Tran and Renu Eapen, their Scientific Meeting and all at ANZUP  fo...2023-08-0157 minGU Cast | Urology PodcastGU Cast | Urology PodcastAlpha PSMA & New Targets in Prostate Cancer | ProsTIC/PCF Global WebinarThis is for hardcore PSMA aficionados!! This is the 7th of our ProsTIC/Prostate Cancer Foundation Global Webinars focussing on all things PSMA theranostics (you can find the rest in our back catalogue stretching back to April 2020). We peek into theranostics beyond what we currently have with beta-emitters like LuPSMA, into the tantalising world of alpha-PSMA theranostics. Multidisciplinary researchers from the PCF-funded TACTICAL project give a sneak into current and future work. Hear from Memorial Sloan Kettering Cancer Center experts Prof Mike Morris, Dr Lisa Bodei and Dr Jason Lewis about very exciting developments in DLL3 imaging and...2023-07-211h 28GU Cast | Urology PodcastGU Cast | Urology PodcastLet's Visit Ireland! The Irish Society of Urology Annual MeetingA GU Cast Ireland Special! Declan recently travelled to the Annual Meeting of the Irish Society of Urology and posted this GU cast special from Killashee House in County Kildare. Apologies in advance for him wallowing in his Irishness! Declan catches up with Urologists David Bouchier-Hayes, Eva Bolton, Catherine Dowling, and Richie Power, to chat about everything from Terence Millen and Peter Freyer to how the Irish are inspiring young women to do urology. Plus we hear about the late Dan Kelly, a legendary Irish urologist who passed away recently. Our Youtube version features some gr...2022-11-2733 minGU Cast | Urology PodcastGU Cast | Urology PodcastAnother fantastic ProsTIC/PCF PSMA theranostics webinarGU Cast is pleased to cross-post another of these excellent ProsTIC PSMA theranostics webinars in collaboration with the Priotate Cancer Foundation's Global Knowledge Exchange programs. This webinar focuses on the new era of PSMA theranostics post-FDA approval. This webinar is co-hosted by Professor Michael Hofman, Nuclear Medicine Physician and Director of ProsTIC at Peter MacCallum Cancer Centre in Melbourne, and GU Cast's own Professor Declan Murphy, with comments from the PCFs Dr Howard Soule and Dr Andrea Miyahira.  Special guest presenters include Professor Silke Gillessen, Professor Ken Herrmann, and Dr Louise Kostos and Dr James Buteau. F...2022-08-081h 27GU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast Conference Highlights | EAU 22 Part 2Part 2 of our #EAU22 highlights from Amsterdam features chats with EAU Guidelines Chair Professor Maria Ribal, the inimitable Associate Professor David Bouchier-Hayes, and a roving report from Dr Sophie Rintoul-Hoad as she sails around Amsterdam's canals. Plus some live reporting from the GU Cast reception at the Hoopman Pub in Amsterdam with Dr Alastair Lamb, Dr Marcus Cumberbatch, Dr Ben Challacombe, and a trio of colorectal surgeons who just love urology. Check out everyone wearing their GU Cast merch! And we also cross-post Dr Matt Cooperberg's UroToday interview with Declan and Renu on the LuTectomy study. Jam packed. 2022-08-0435 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast Conference Highlights | EAU 22 Part 1Declan and Renu bring you the first of their two part #EAU22 conference highlights from Amsterdam. How great to have the EAU back in person! We catch up with lots of old friends and bring you top scientific highlights. Guests on this episode include Jim Catto, Peter Black, Tim O'Brien, Eva Comperat, plus some fun on EAU TV with Chris Sweeney and Alberto Briganti. Also on YouTube here Our website GU Cast2022-07-2927 minGU Cast | Urology PodcastGU Cast | Urology PodcastPSMA Highlights at ASCO 22GU Cast returns to one of our favourite topics - PSMA imaging and theranostics! We chat with Nuclear Medicine Physician Professor Michael Hofman, and GU Medical Oncologist, Associate Professor Arun Azad, about some PSMA highlights at the recent ASCO Annual Meeting. Michael presented the eagerly anticipated overall survival data from the TheraP trial in the oral abstract session, and discusses the findings with Arun, Renu and Declan. They also discuss another important paper in the oral abstract session - an analysis of the quantitative parameters of PSMA PET/CT scans in the VISION study. Also available...2022-06-2336 minGU Cast | Urology PodcastGU Cast | Urology PodcastLet's Visit...The Martini-Klinik, Hamburg (Part 2)Part 2 of Declan's visit to the Martini-Klinik in Hamburg. Today he chats with Professor Derya Tilki, Urologist and Clinician Researcher, about their ongoing  research activities, including the huge database of radical prostatectomy outcomes which now includes a staggering 35,000 patients. Plus a fantastic trip to the operating room with Professor Tobias Maurer to perform PSMA-guided salvage pelvic lymph node dissection. Declan gets to scrub in and learn from Tobias about his huge experience in this evolving area.Also cross-posted to our YouTube channel, featuring Declan's up close experience assisting Tobias perform PSMA radio guided surgery2022-06-0525 minGU Cast | Urology PodcastGU Cast | Urology PodcastLet's Visit...The Martini-Klinik, Hamburg (Part 1)Declan Murphy continues his sabbatical adventures in Europe by spending a few days at the famous Martini-Klinik in Hamburg. The Martini-Klinik is the world's largest radical prostatectomy centre, and is preparing to move to a new building to increase their capacity even more. In this first part of a two-part podcast/videocast, Declan chats with Chief of Urology Professor Markus Graefen, and spends some time in the operating rooms with Markus and Professor Alexander Haese, looking at the Neurosafe frozen section technique which was developed at the Martini Klinik. Plus we discuss a new randomised trial of pelvic...2022-05-2936 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast | APCCC Highlights Part 3In his third and final podcast from Lugano, Declan chats with Dr Axel Merseberger (Lubeck), Dr Jochen Walk (Marseille), Ms Jane Fisher (Melbourne), and Dr Chris Sweeney (Boston/Adelaide). Plus listen out for fantastic father and son act, Professor Joe and Oisin O'Sullivan, who played for the crowds outside the Villa Cian. Silke Gillessen and Aurelius Omlin were also pleased to announce the dates of the next APCCC which will take place from 25-27 April 2022 in spectacular Lugano. GU Cast is our regular podcast brought to you by Professor Declan Murphy and Dr Renu Eapen, Ur...2022-05-1736 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast | APCCC Highlights Part 2Declan continues his three part podcast from the Advanced Prostate Cancer Consensus Conference (APCCC) 2022. Imaging played a very dominant (and disruptive) role at APCCC 2022, especially PSMA PET/CT with lots of “train has left the station analogies” and a healthy amount of panellists wanting to stay on the platform! Today Declan speaks with four imaging experts to hear their thoughts. Nuclear Medicine physicians Professor Michael Hofman (Melbourne), Professor Stefano Fanti (Bologna) and Dr Ken Herrmann (Essen), were joined by MRI guru Professor Anwar Padhani (London). Fair to say the prostate cancer world needs help figuring out what to do...2022-05-0934 minGU Cast | Urology PodcastGU Cast | Urology PodcastLet’s Visit…the Netherlands Cancer Institute, AmsterdamDeclan Murphy stops off at the world-famous Netherlands Cancer Institute (NKI) in Amsterdam for a couple of days to visit his old friend, Professor Henk van der Poel. Henk is Consultant Urologist and Chief of Urology at the NKI, and leads a fantastic team with world-renowned expertise in GU oncology. Declan spends a day in the operating room to watch Henk perform robotic radical prostatectomy and extended pelvic lymph node dissection using a fluorescence-guided approach to detect sentinel lymph nodes, and hears the latest about Henk’s ongoing trials in this area. He then spends a da...2022-05-0622 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast | APCCC Highlights part 1To celebrate the return of the world’s premiere prostate cancer meeting, GU Cast is very pleased to bring you the first of three special editions from the Advanced Prostate Cancer Consensus Conference 2022. GU Cast co-host Professor Declan Murphy joined other panellists and delegates in beautiful Lugano, and recorded interviews with many other speakers and attendees, and captured some fantastic footage by Lake Lugano (check out our YouTube version). In this episode, Declan chats with APCCC Convenors, Dr Silke Gillessen and Dr Aurelius Omlin, and panellists Dr Pierre Blanchard, Dr Jochen Walz, and Dr Bertrand Tombal, along with patient re...2022-05-0134 minGU Cast | Urology PodcastGU Cast | Urology PodcastLate night PSMA chat at the ProsTIC PreceptorshipGU Cast moved on-site this week to the ProsTIC Preceptorship in Melbourne, a state-of-the-art meeting focusing on PSMA Theransotics, led by the PCF-funded ProsTIC Centre of Excellence at Peter MacCallum Cancer Centre. What a great meeting! In-person and virtual with on-demand available for two years (links below). We invited international guest Dr Tom Hope, Nuclear Medicine Physician and Radiologist at the University of California San Francisco, to join us for a late-night drink in our GU Cast studio at the Sofitel in Melbourne, to have a chat about all things PSMA. Along with Australian PSMA pioneers Professor Michael...2022-04-0547 minGU Cast | Urology PodcastGU Cast | Urology Podcast#UrologistsForUkraineToday Declan and Renu chat with two young doctors who have spent the past few weeks on the Poland-Ukraine border, helping with the refugee crisis triggered by Russia's invasion of Ukraine. Just amazing stories of desperation and tragedy, with some inspiring tales of resilience and generosity. Dr Laura Bukavina is a Urology Fellow at Fox Chase Cancer Centre in Philadelphia, and Dr Alberto Castro is a research Fellow at Fox Chase, soon to start his urology residency. Laura is a Ukrainian and tells the story of why she got on a plane as soon as the invasion started...2022-03-1336 minGU Cast | Urology PodcastGU Cast | Urology PodcastDo MRI-targeted prostate biopsies lead to over-diagnosis and over-treatment??!!Well the data are clear, says eminent biostatistician and research methodologist, Dr Andrew Vickers of Memorial-Sloan Kettering Cancer Centre in New York. In some well constructed recent articles, Andrew has really made us think again about the impact of  moving to MRI-directed triage and targeted biopsies, instead of "blind" systematic biopsies. Could it be that this strategy actually leads to harm, rather than the clear benefits which many assume that MRI has brought to prostate cancer diagnostics??We are joined today by Andrew, and two household names in the world of MRI-targeted biopsies to defend the practice (which i...2022-03-0346 minGU Cast | Urology PodcastGU Cast | Urology PodcastConferences are back!!!!2022 finally sees some return to normality in the world of GU conferences. Hooray! Today we chat with the leaders of two of our absolute favourite meetings - the European Association of Urology (EAU) Annual Meeting, and the Advanced Prostate Cancer Consensus Conference (APCCC). We are joined from Germany by Chair of the EAU Scientific Committee Professor Peter Albers, and from Switzerland by President of the APCCC, Professor Silke Gillessen. And we were pleased to say there is a lot to look forward to!!! These meetings are back to their usual in-person format, but as you will hear, they...2022-02-2432 minGU Cast | Urology PodcastGU Cast | Urology PodcastPRIMARY 2 opens - another fantastic randomised trial of PSMA PET/CT!This week saw the opening of another multi-centre randomised trial of PSMA PET/CT in Australia. And it's a cracker! PRIMARY 2 follows on from the success of the PRIMARY trial published in European Urology recently (see links below). It is aimed at men with some clinical suspicion of prostate cancer, but no definite lesion on MRI (PIRADS 2/3). Is it ok to just to monitor these men (a la PRECISION)? Many will still undergo prostate biopsy if there is a high clinical suspicion (such as high PSA density, palpable lesion, strong family history), but could PSMA play a role in...2022-02-1730 minGU Cast | Urology PodcastGU Cast | Urology PodcastPSA - creating more Patient Stress and Anxiety than usual!In the past few weeks we noticed some strangeness appearing in the PSA reports from one of our major pathology providers here in Australia. Dorevitch Pathology had started reporting PSA levels using BOTH the Siemens Atellica assay, AND the Abbott Alinity assay on the same blood sample. So patients were turning up with two PSA results for the same sample - and were these the same?? Afraid not! Sometimes the differences were huge, leading to much "Patient Stress and Anxiety". So we decided to get some expert help, and invited Dr Alan McNeil, Chemical Pathologist at Dorevitch, to...2021-11-2940 minGU Cast | Urology PodcastGU Cast | Urology PodcastVISION - "a dilapidated, delinquent, unethical control arm"So said UCSF Oncologist and major league podcaster Dr Vinay Prasad in his recent Plenary Session podcast, reviewing the VISION trial in NEJM. We have already covered VISION here at GU Cast, but we decided to invite Vinay on the podcast to de-visit VISION and other aspects of trial design. Vinay is a Haematologist Oncologist at the University of California, San Francisco, and researcher interested in health policy. He is author of "Malignant", and has huge listenership to his Plenary Session Podcast and YouTube channel. He is certainly not afraid to call out issues with trial design and health...2021-10-2245 minGU Cast | Urology PodcastGU Cast | Urology PodcastActive surveillance no longer "preferred" management for low-risk prostate cancer? Really NCCN??! JeezThis one really slipped under the radar when the National Comprehensive Cancer Centre Network (NCCN) Prostate Cancer Guideline Panel released their updated guidelines a few weeks ago. That is until Dr Dan Lin mentioned it to Dr Matt Cooperberg, who promptly flagged it to his very large Twitter following. And what a reaction! Almost universally panned by the urological community, especially advocates for active surveillance (AS), who have long despaired at the low rates of AS uptake in the US, and who worry that this change may lead to even lower rates of AS in the USA. ...2021-10-0740 minGU Cast | Urology PodcastGU Cast | Urology PodcastSTAMPEDE delivers yet again!Some huge data coming out of #ESMO21 this week! And as ever, the amazing STAMPEDE trial delivers another practice-changing headline grabber. This time it's a focus on so-called "M0 high-risk" patients in STAMPEDE, with clear data showing that the addition of two years of abiratrone acetate to standard of care provides a massive benefit in metastasis-free survival and overall survival. We are joined today by STAMPEDE co-PI Professor Noel Clarke, Urologist and Professor of Urological Oncology at the Christie NHS Foundation Trust, and Professor Silke Gillessen, Medical Oncologist at the Oncology Institute of Southern Switzerland, and also a...2021-09-2348 minGU Cast | Urology PodcastGU Cast | Urology PodcastPSMA PET/CT prior to biopsy?? PRIMARY trial in Eur UrolAre GU Cast overly interested in PSMA imaging and theranostics??! Yep, afraid so! So no surprise that we're featuring this very interesting prospective trial published in European Urology this week. The objective is to evaluate the role of PSMA PET/CT prior to prostate biopsy ie in the early detection space. Can this augment mpMRI? Or replace it? Or is it all just madness due to profligate access to PSMA in Australia??!We are joined by PI Professor Louise Emmett, Nuclear Medicine Physician at St Vincent's in Sydney, to chat about the PRIMARY trial, and co-author Associate Professor...2021-09-1338 minGU Cast | Urology PodcastGU Cast | Urology PodcastThat Letter | Moving beyond, with Neil Fleshner, Sarah Psutka & Nathan LawrentschukSo there we were, thinking we did a nice job highlighting the #Manels paper published in European Urology recently, and basking a little bit in the glow of positivity it brought to the topic of gender diversity in Urology. We were also really pleased to see the accompanying Editorial which outlined the European Urology position on gender diversity and equality, led by Associate Editor Professor Sarah Psutka and senior members of the Journal's Editorial Board. Then, a Letter to the Editor appeared and provoked quite a response on social media.  It described the results of the European Urology p...2021-09-0639 minGU Cast | Urology PodcastGU Cast | Urology PodcastAlex Kutikov has a picture of Toni Chouieri on his desk! Plus Keynote 564 gets a GrillingThis headline may be true (check our YouTube version for proof!), but the bromance certainly hit a bumpy patch when it came to discussing Keynote 564 on GU Cast today! We congratulate Dr Toni Chouieri (Medical Oncologist and Director of the Lank Center for GU Oncology, Dana Farber Cancer Institute), and colleagues for the publication of Keynote 564 in NEJM recently, and to Toni for his plenary at ASCO this year. And we welcome Dr Alex Kutikov, Urologist and Chief of Urologic Oncology at Fox Chase Cancer Centre, and an old mate of Toni's, and studio guest Associate Professor Ben...2021-08-3045 minGU Cast | Urology PodcastGU Cast | Urology PodcastMajor reform of surgical training in the UK - goodbye to indicative numbers!In May 2018, Urologist Dr Daron Smith of University College Hospital, London, wrote an impassioned open letter to announce that he was stepping down as an educational supervisor in urology, due to his frustration with the burdensome administrative tools embedded in the UK surgical training system. His message resonated with many. This month, a new curriculum and training system comes into effect, with significant changes to reduce this burden. But do they go far enough?Declan and guest co-cost, Dr Sophie Riddel-Hoad, chat to Daron Smith, President of the BAUS Section of Trainees Dr Neil Harvey, and Past-President...2021-08-1649 minGU Cast | Urology PodcastGU Cast | Urology PodcastTREXIT! Is the end in sight for transrectal prostate biopsy??Transperineal biopsy has gone from being a fringe pursuit for a bunch of enthusiasts, into primetime in countries like Australia and the UK where it accounts for more than 50% of prostate biopsies. We are joined today by Associate Professor Jeremy Grummet, Urologist at Alfred Health and Monash Medical School, who has been a long-standing proponent of transperineal prostate biopsy, and who contributed to a very nice pro/con debate in European Urology Open Science this month on teh topic of "TREXIT", ie an exit for transrectal prostate biopsy. We credit Dr Rick Popert at Guy's Hospital in London for...2021-08-1237 minGU Cast | Urology PodcastGU Cast | Urology PodcastPCF Global Webinar | The VISION TrialGU Cast once again joins up with our friends at the Prostate Cancer Foundation (PCF), and the Prostate Cancer Imaging & Theranostics Centre of Excellence (ProsTIC) at Peter MacCallum Cancer Centre to bring you another Global Webinar focussing on PSMA theranostics. Today's webinar features the VISION trial, recently published in the New England Journal of Medicine, and includes the first and senior authors, Dr.s Oliver Sartor and Michael Morris. We also welcome panellists  Dr Alicia Morgans, Associate Professor Sze-Ting Lee, Dr James Buteau, and our co-hosts from the PCF, Dr Howard Soule and Dr Andrew Miyahira. This w...2021-07-221h 30GU Cast | Urology PodcastGU Cast | Urology Podcast"We're no longer presenters; we're broadcasters", says BAUS President Tim O'BrienTim O'Brien returns to GU Cast today, basking in the afterglow of a very successful British Association of Urological Surgeons (BAUS) Annual Meeting, virtual of course. Tim last joined us in August 2020 when he had just taken up the reins as BAUS President, and was dealing with the challenge of running a virtual BAUS Annual Meeting. One year on, and following a very well received virtual BAUS Annual Meeting last month, we consider the future of scientific meetings. Brilliant insights from Tim, including a memorable discussion about how we all need to acquire  broadcast skills! Hear how BAUS S...2021-07-0138 minGU Cast | Urology PodcastGU Cast | Urology PodcastCan MRI replace biopsy for patients on active surveillance? It already has!Fascinating GU Cast today focussing on the role of MRI scanning for patients on active surveillance (AS) for prostate cancer. We are joined by two of the world's leading experts on prostate MRI to discuss two recent systematic reviews on this topic.  Professor Anwar Padhani, Radiologist at Mt Vernon Cancer Centre and the Institute of Cancer Research  in London, and Professor Caroline Moore, Urologist at University College London, give some fascinating insights and tackle some controversial questions. Patients and clinicians would love to avoid further biopsies as part of active surveillance monitoring. However, repeat biopsy remains a strong re...2021-06-2438 minGU Cast | Urology PodcastGU Cast | Urology Podcast"Put a mirror in front of all of us" - #ManelsCracking episode today, following hot on the heels of the systematic review recently published in European Urology focussing on #manels in urology. We cross the globe to hear from first author Dr Jeremy Teoh in Hong Kong, senior author Dr Maria Ribal in Barcelona, and co-authors Dr Stacy Loeb in New York, and our own Declan Murphy in Melbourne. This paper has got a big reaction on social media and we review some of the best and the worst of twitter in our chat today. Enjoy! Links:Eur Urol paper on #manelsJeremy T...2021-06-1442 minGU Cast | Urology PodcastGU Cast | Urology PodcastPost-ASCO VISION deep dive - with Dr Mike MorrisBig week for prostate cancer ( especially for PSMA enthusiasts like us!), with the phase III VISION trial heading the plenary session at the ASCO Annual Meeting. VISION is the long-awaited pivotal randomised trial of Lu-PSMA vs standard of care for men with progressive mCRPC following chemo +/- AR pathway inhibitors. Lots of stuff to dive into, even as we await the NEJM paper. We scrutinise the control arm and dive deep into teh issue of imaging and patient selection.Regular hosts Professor Declan Murphy and Dr Renu Eapen are joined by some of our experienced Lu-PSMA specialists at...2021-06-0840 minGU Cast | Urology PodcastGU Cast | Urology PodcastFinancial toxicity in GU Oncology, with Dr David PensonToday Declan and Renu recall one of the highlights of ASCO GU 2020 (the last real physical meeting!!),  when Dr David Penson delivered his keynote address on financial toxicity in GU Oncology. David's team also followed up with a fantastic systematic review on this completely under-discussed topic in European Urology Oncology recently (link below). David is Professor and Chair of Urology at Vanderbilt University Medical Centre in Nashville, and has had a distinguished career investigating quality of life in prostate cancer patients, particularly as PI of the Prostate Cancer Outcomes Study. No holds barred today as we discuss everything from b...2021-05-1335 minGU Cast | Urology PodcastGU Cast | Urology PodcastPCF Global Prostate Ca Webinar - TheraP trialGU Cast is back! Declan and Renu took a break over the Melbourne Summer and are fully recharged with a great schedule of podcasts coming up for 2021.We kick off today with the fourth in our series of webinar collaborations with the Prostate Cancer Foundation and the ProsTIC team at Peter MacCallum Cancer Centre. Today's webinar had 589 live attendees from more than 40 countries, tuning in to hear the latest in PSMA theranostics for advanced prostate cancer. ON GU Cast today we cross-post the audio from today's webinar focussing on the TheraP trial, recently published in the Lancet. T...2021-02-261h 29GU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast Year in ReviewToday we are getting together on New Year's Eve 2020 to look back on the year that was. Very forgettable for many reasons(!), but also some great moments on GU Cast that we want to share with you on our Year in Review podcast. Since our launch episode in March 2020, we have posted 45 episodes and have had many thousands of downloads every month. Our audience  is truly global with listeners from 75 countries in 2020,  the majority of whom (59%) are from outside Australia. We play back some very memorable moments from the past nine months, and chat about some of our...2020-12-3146 minGU Cast | Urology PodcastGU Cast | Urology PodcastGU Cast PROSPECT Summer SeriesWe know that many of our listeners are in the depths of a tough COVID Winter in the Northern Hemisphere, so we thought we might bring you some summer cheer from Australia where the sun is shining and COVID is less of an issue! We have joined with our friends at PROSPECT, a prostate cancer educational initiative which has been running in Australia for eight years. to bring you a 3-part podcast summer series focussing on our favourite hot topics in prostate cancer. Today we focus on two areas with a big crossover - so-called "non-metastatic (M0)" castration-resistant p...2020-12-2243 minGU Cast | Urology PodcastGU Cast | Urology PodcastFDA approves PSMA PET/CT! We chat with UCSF teamBig day today with the approval of Ga68-PSMA PET/CT by the US Food and Drugs Administration (FDA). The FDA have approved a combined academic application from the University of California San Francisco (UCSF) and the University of California Los Angeles (UCLA), and means that those two centres now have FDA approval to use PSMA PET/CT for staging newly-diagnosed prostate cancer, as well as those with suspected recurrence following previous treatment. Today we chat with the UCSF team behind the application, led by Dr Thomas Hope, Nuclear Medicine Physician and Radiologist, and his urology colleagues Dr...2020-12-0335 minGU Cast | Urology PodcastGU Cast | Urology PodcastHardening up on prostate health - a Movember special"Men urged to harden up on prostate health" - so goes the title of Libbi Gorr's interview with our own Declan Murphy when she chatted with him this week on her ABC Radio show, "This Weekend Life". A no-holds barred chat on all things prostate to coincide with Movember. Featuring calls from patients, and a discussion about how often men should ejaculate! LinksLibbi's show on ABC Radio2020-11-1908 minGU Cast | Urology PodcastGU Cast | Urology PodcastGoing Nuclear | GU Oncology highlights from #EANM20The European Association of Nuclear Medicine (EANM) Annual Meeting is the world's leading nuclear medicine congress, and took place (virtually) last week. From being a very minor part of nuclear medicine just a few years ago, GU Oncology is now one of the most exciting areas in nuclear medicine, and this year's EANM Meeting featured a huge amount of original research in prostate cancer and other GU malignancies. Today we are joined by EANM Congress Chair, Dr Stefano Fanti from Bologna, Italy, and Dr Irene Burger, Head of Nuclear Medicine in Baden, to review the top papers from...2020-11-1041 minGU Cast | Urology PodcastGU Cast | Urology PodcastNAVIGATE-ing active surveillance optionsToday we focus on the NAVIGATE study,  a randomised trial of an online decision aid for men and their partners recently diagnosed with localised prostate cancer. Active surveillance is the preferred option for many men with low-risk prostate cancer, and may also be recommended for some men with favourable intermediate-risk prostate cancer, but many patients find the idea of surveillance to be stressful, and find the choice of management options to be bewildering. So today we chat with some of the team behind the NAVIGATE study which is designed to address some of these issues. NAVIGATE is running in A...2020-10-2940 minGU Cast | Urology PodcastGU Cast | Urology Podcast#ESMO20 highlights with Ben Tran and Ciara ConduitRegular GU Cast guest, Dr Ben Tran, joins us today to review some highlights from the recent virtual #ESMO20 Annual Meeting. Ben made headlines himself at this year's meeting as he presented his phase 1 study of AMG160 was selected for the prostate cancer plenary session (you got to tune in to hear him explain what a half-life extended bi-specific T cell engager is! Peter Mac Phase I and GU Fellow, Dr Ciara Conduit, also joins us to discuss this and other highlights including IPAT, PROfound, and the Checkmate 9ER study for mRCC. Usual hosts Declan Murphy and Renu Eapen. 2020-10-1435 minGU Cast | Urology PodcastGU Cast | Urology PodcastAnother PCF Global Knowledge Exchange - Next Generation PSMAToday we join forces again with our good friends at the Prostate Cancer Foundation (PCF) to bring you the podcast version of the PCF Global Knowledge Exchange, this time focussing on Next Generation PSMA. Today's event is brought to you by PCF in conjunction with the Prostate Imaging and Theranostics Centre of Excellence (ProsTIC) at Peter MacCallum Cancer Centre in Melbourne. Your hosts are Dr Howard Soule and Dr Andrea Miyahira from the PCF, and Professor Michael Hofman and Professor Declan Murphy from ProsTIC. PSMA imaging and theranostics are among the most exciting areas of research in prostate...2020-10-081h 39GU Cast | Urology PodcastGU Cast | Urology PodcastRAVES clarifies post-operative radiotherapy in prostate cancerA big week for prostate cancer in the Lancet! No less than three much-anticipated randomised trials to investigate the role of adjuvant vs salvage radiotherapy in prostate cancer, were published in the Lancet and Lancet Oncology this week, plus a pre-planned meta-analysis of all three. RAVES, RADICALS-RT, and GETUG-AFU 17, each examined the issue of post-operative radiotherapy in men at risk of biochemical recurrence, and randomised those men to receive radiotherapy prior to PSA recurrence (adjuvant), or at the first sign of PSA recurrence (early salvage). There were some differences in patient population and trial design, but the overall message...2020-10-0132 minGU Cast | Urology PodcastGU Cast | Urology PodcastThe kids are in charge! Trainee-led collaborative research in UrologyToday we focus on trainee-led collaborative research, focussing on three of the best examples out there. We chat with the leaders of the British Urology Researchers in Surgical Training (BURST), the European Society of Residents in Urology (ESRU), and the Australian Young Urology Researchers Organisation (YURO). These groups have a number of missions, including networking and mentorship for trainees, but they also have a particular interest in collaborative research. We chat with Veeru Kasi and Meg Kulkarni from BURST, Diego Carrion Monsalve from ESRU, and Ellen O'Connor from YURO, about the beginnings of their respective organisations, how they function...2020-09-2447 minGU Cast | Urology PodcastGU Cast | Urology Podcast"I don't like reading papers" | with CUA Journal Editor-in-Chief, Mike LeveridgeContinuing our season of chats with newly-minted Editors-in-Chief of top urology journals, today we chat with Dr Mike Leveridge of the Department of Urology, Queen's University, Ontario. Mike has just taken the reins as Editor-in-Chief of the Canadian Association of Urology (CUA) Journal, one of our favourite national journals, and has just published his opening editorial. CUA J is open access with no article processing fees - the rest of teh world should follow this example!!One of our all time favourite friends in North America, and a great choice to lead this really useful journal. Usual hosts...2020-09-1031 minGU Cast | Urology PodcastGU Cast | Urology PodcastIMPORTANT STUFF, with Ben DaviesUro-Twitterati legend Dr Ben Davies joins us today to trawl through his Twitter feed and share his wisdom on everything from tomatoes to leadership positions in Urology. Ben is Professor of Urology at the University of Pittsburgh, Chief of Urology at Shadyside/Hillman Cancer Centre and Director of the Uro-Oncology Fellowship Program. No holds barred chat with one of our favourite friends in Urology! With your usual hosts, Declan Murphy and Renu Eapen. Ben's Twitter feed https://twitter.com/daviesbj 2020-09-0230 minGU Cast | Urology PodcastGU Cast | Urology Podcast"A Home and a Vehicle" | New Editor-in-Chief Freddie Hamdy discusses the future of the BJUIProfessor Freddie Hamdy, Professor of Urology at the University of Oxford, has recently taken up the reigns as Editor-in-Chief of the British Journal of Urology International (BJUI) and has just published the first edition with his new editorial team. The BJUI has been around for more than 90 years and is one of the top journals in the world of urology. Its impact factor rose to an all-time high under the leadership of Prof Hamdy's predecessor. Professor Prokar Dasgupta, who also led a huge change to embrace digital and social media, and therefore Prof Hamdy takes over at an exciting...2020-08-3030 minGU Cast | Urology PodcastGU Cast | Urology PodcastBAUS President Tim O'Brien on catalysts for changeTim O'Brien, Consultant Urologist at Guy's & St Thomas' NHS Foundation Trust in London, joins GU Cast to chat about his recent appointment as President of The British Association of Urological Surgeons. Tim has taken the reigns of BAUS during these most extraordinary of times, and is determined to make the most of the opportunities! Nothing like a pandemic to help make some changes. Tim joins usual hosts Declan Murphy and Renu Eapen for a most entertaining and insightful chat. 2020-08-2541 minGU Cast | Urology PodcastGU Cast | Urology PodcastUSANZ President discusses trainee issues during COVIDToday we are joined by USANZ President, Dr Stephen Mark, to discuss the big challenges faced by trainees during COVID. We include soundbites from many trainees and aspiring trainees who sent in voice memos to highlight the stresses and concerns they have - some  amazing comments! Stephen responds to these concerns and gives us a glimpse into USANZ plans for the future. Regular hosts Declan Murphy and Renu Eapen are joined by Associate Professor Nathan Lawrentschuk. 2020-08-1343 minGU Cast | Urology PodcastGU Cast | Urology PodcastElective surgery restrictions in Melbourne - what does this mean for GU cancer patients?With the COVID pandemic situation continuing to worsen in Melbourne, further restrictions have been put in place for elective surgery. Pre-op COVID swabs are already mandatory, and now only the most urgent surgeries can go ahead. We are joined by the Directors of three of Melbourne's busiest urology cancer centres to see what this means for patients. Professor Damien Bolton from the Austin, Associate Professor Nathan Lawrentschuk from the Royal Melbourne Hospital (and Peter Mac), and co-host Professor Declan Murphy from Peter Mac. Dr Renu Eapen is co-host as ever. 2020-07-3032 minGU Cast | Urology PodcastGU Cast | Urology PodcastFocal therapy and salvage radical prostatectomyToday we chat with Dr Paul Cathcart, Urologist at Guy's & St Thomas' NHS Foundation Trust in London, who has a specialist interest in salvage radical prostatectomy. Paul is one of the world's most experienced salvage prostatectomists and joins us to chat about patient selection and surgical technique to optimise outcomes, especially for patients who have undergone focal therapy. Post-HIFU/brachy/cryo/Nano knife - he does them all! And has published lots of data in this area.Paul also chats about the UK National Prostate Cancer Audit as he leads the Quality group in this huge project. Co-hosts...2020-07-2336 minGU Cast | Urology PodcastGU Cast | Urology PodcastA great surgical randomised trial! Plus the amazing ProximieToday Melbourne is back in lockdown (boo), so to cheer ourselves up, we bring you a fantastic GU Cast with two great guests! Dr Jim Porter from Seattle has hit the headlines twice recently; first with a superb randomised trial of a point of surgical technique during robotic prostatectomy recently published in the BJUI; and second, the global headlines that he made when he mentored Dr Archie Fernando perform a complex robotic surgery in London, while in his pyjamas in Seattle! We chat with the founder and CEO of Proximie, whose technology enabled this, Dr Nadine Haram, an extraordinary...2020-07-0935 minGU Cast | Urology PodcastGU Cast | Urology PodcastTelehealth tips with Archie FernandoDr Archie Fernando is a Consultant Urologist at Guy's & St Thomas' NHS Foundation Trust in London, specialising in testicular cancer and retroperitoneal fibrosis. BAUS posted a terrific video which she did recently to share her perspectives on telehealth, based on an interesting case she had recently had, and she shares seven great tips on telehealth for clinicians. Join Declan and Renu for a terrific podcast with Archie. Here is a link to her original video https://youtu.be/P3c3ZvVI-OY 2020-06-3036 minGU Cast | Urology PodcastGU Cast | Urology PodcastPrecision prostate cancer simplified with Neeraj AgarwalWe are joined today by the fantastic Dr Neeraj Agarwal of the Huntsman Cancer Institute in Utah to discuss some contentious areas in mCRPC, especially around DNA repair defects, immunotherapy and other targeted therapies. Also joined again in studio by our colleague Associate Professor Arun Azad, and regular hosts Declan Murphy and Renu Eapen.2020-06-2532 minGU Cast | Urology PodcastGU Cast | Urology PodcastMore bladder cancer!!! With Petros GrivasGU Cast chats to Dr Petros Grivas, GU Medical Oncologist at the University of Washington in Seattle, about the JAVELIN 100 trial which featured in the plenary session at ASCO20 recently. Petros is senior author on this practice-changing study of "switch maintenance" in metastatic bladder cancer, and he joins us today to explain some of the finer details of the study. With audio cameos from Tom Powles, Betsy Plimack, and Vinay Prasad (yikes!). Declan and Renu were also delighted to have Associate Professor Andrew Weickhardt join them in studio today. Andrew is a GU Medical Oncologist at the Olivia-Newton J...2020-06-1436 minGU Cast | Urology PodcastGU Cast | Urology PodcastPCF Global Webinar | TheraP trial in focusAnother most enjoyable webinar from our friends at the Prostate Cancer Foundation, this time focussing on the TheraP trial recently presented at #ASCO20, a randomised trial of Lu-PSMA vs cabazitaxel in progressive mCRPC. Professor Michael Hofman presents the data and is joined by an esteemed global panel including Professor Ian Davis, Professor Cora Sternberg and Professor Wolfgang Weber. Co-hosted by Professor Declan Murphy and Dr Howard Soule. More than 500 registrants from over 40 countries joined in, many of whom contributed to a very lively discussion. Enjoy!2020-06-111h 28GU Cast | Urology PodcastGU Cast | Urology PodcastBCG and COVID19 - a BADAS combinationDr Ashish Kamat, Professor of Urologic Onology at MD Anderson Cancer Centre joins us for a chat about the BADAS trial which he is leading. Fascinating trial to see if BCG vaccination might protect health care workers. And of course we talk bladder cancer as Ashish is a huge key opinion leader with many leadership roles in bladder cancer research and advocacy. usual hosts Declan Murphy and Renu Eapen are joined by Associate Professor Nathan Lawrentschuk from Peter Mac. Nathan is also Director of Urology at the Royal Melbourne Hospital and leads Bladder Cancer Australia. 2020-06-0831 minGU Cast | Urology PodcastGU Cast | Urology PodcastMonty talks renal cancer at #ASCO20Dr Sumanta Pal from City of Hope, CA, joins us to discuss renal cancer highlights at virtual #ASCO20. Monty heads the renal cancer program at City of Hope and is a huge KOL in renal cancer. Also great fun on Twitter @montypal of course. Enjoy this fireside chat with Monty, Dr Ben Tran, medical oncologist at Peter Mac, and regular hosts Declan Murphy and Renu Eapen. PS our podcast art today features Monty and Eric Jonasch when they popped in to see us at Peter Mac in February 2018. Nice pose gents!2020-06-0730 minGU Cast | Urology PodcastGU Cast | Urology PodcastBladder cancer finally in the limelight with an ASCO Plenary!Dr Elizabeth Plimack, Chief of GU Medical Oncology at Fox Chase Cancer Centre, Philadelphia, joins us to discuss bladder cancer highlights at ASCO 20. For the first time, urothelial cancer featured in an ASCO Plenary with Dr Tom Powles presenting the primary endpoint of JAVELIN100, a practice-changing study of switch-maintenance in metastatic urothelial cancer. Betsy did a fantastic discussion in the plenary and joins us today to discuss this and others. Regular hosts Declan Murphy and Renu Eapen are joined by Dr Ben Tran, GU Trials Lead at Peter MacCallum Cancer Centre.2020-06-0430 minGU Cast | Urology PodcastGU Cast | Urology PodcastOliver Sartor's favourite bits | #ASCO20 prostate cancer highlightsThe first in our series of post-#ASCO20 podcasts. Today we chat with Dr Oliver Sartor of Tulane Cancer Centre about his favourite prostate cancer moments from virtual #ASCO20. PSMA imaging and therapy, neo-adjuvant intensive ADT, M0 CRPC etc etc - all get a mention in a whirlwind run through the main prostate cancer sessions. Regular hosts Declan Murphy and Renu Eapen are joined by Peter Mac colleagues, Associate Professor Arun Azad and Professor Michael Hofman. 2020-06-0242 minGU Cast | Urology PodcastGU Cast | Urology PodcastThe post-prostatectomy journey - things I wish we knew back thenWe are joined today by Alan and Fiona White to discuss their perspectives as a couple who have been on this journey, and who spend a lot of time supporting other couples. Alan had an open radical prostatectomy in 2011, and himself and Fiona have developed https://www.theprostatezone.com to help others on the journey. Regular hosts Declan Murphy and Renu Eapen are also joined by prostate cancer Nurse Consultant, Emma Birch. 2020-05-2929 minGU Cast | Urology PodcastGU Cast | Urology PodcastOf Mice and Men - reposted podcast from ABC Radio NationalWe are re-posting this podcast which ABC Radio National posted in Feb 2020, featuring our own Declan Murphy and Peter Mac colleague, Professor Rob Ramsay, top scientist and prostate cancer patient. Some wonderful perspectives and very nicely put together by Natasha Mitchell from the Science Friction podcast at the ABC. Here is their blurb - You're a top cancer scientist. You think you know a lot about the disease. And then you get it. Suddenly you're "A Cancer Patient", and one of your colleagues is wielding the (robotic) scalpel in your surgery. Tables are turned, but on...2020-05-2528 minGU Cast | Urology PodcastGU Cast | Urology PodcastSTAMPEDE and all thatToday we are joined by Professor Nick James, Principal Investigator of the STAMPEDE study; an amazing ongoing series of practice-changing randomised trials for men with advanced prostate cancer. Nick discusses recent highlights of STAMPEDE, imminent developments in STAMPEDE, the impact of PSMA PET/CT, as well as some challenges in the COVID era. He also discusses his recent move from Birmingham to the Institute of Cancer Research/Royal Marsden, and his son's recent Zoom wedding in South America! Regular hosts Declan Murphy and Renu Eapen are joined in studio by Associate Professor Arun Azad, medical oncologist at Peter MacCallum...2020-05-2137 minGU Cast | Urology PodcastGU Cast | Urology PodcastPreparing for ProstatectomyToday we are joined by Nurse Consultants, Emma Birch and Marc Diocera, and also by patient advocate Alan White, to discuss how they work together to prepare patients and their loved ones who are coming up to robotic prostatectomy. They describe the evolution of their "Robocare" program over teh past ten years, and look ahead to how COVID19 is creating opportunities to make it even more accessible. Hosted by Declan Murphy and Renu Eapen. 2020-05-1834 minGU Cast | Urology PodcastGU Cast | Urology PodcastUrotoday and GU Cast get togetherToday we hook up with our good friends at Urotoday.com. Dr Alicia Morgans interviews Professor Declan Murphy for the Urotoday.com website, and we are cross-posting as a GU Cast podcast, introduced by Dr Renu Eapen. Alicia interviews Declan about the COVID situation in Australia as part of the Urotoday.com global overview. 2020-05-1716 minGU Cast | Urology PodcastGU Cast | Urology PodcastSilver Linings! With Matt CooperbergDr Matt Cooperberg from UCSF joins us on GU Cast to give us his Top 5 "Good Things to Come Out of COVID". The usual mixture of banter and bonhomie with Declan Murphy and Renu Eapen from Peter MacCallum Cancer Centre. Enjoy!!2020-05-1431 minGU Cast | Urology PodcastGU Cast | Urology PodcastSBRT and prostate cancer | Three global experts have a chatToday we are joined by three giants in the world of stereotactic-assisted body radiotherapy (SBRT), to discuss the use of SBRT in various stages of prostate cancer. Associate Professor Shankar Siva from Peter MacCallum Cancer Centre joins us in the studio, along with Dr Alison Tree from the Royal Marsden in London, and Dr Piet Ost from Ghent. Your usual hosts are Professor Declan Murphy and Dr Renu Eapen. 2020-04-2935 minGU Cast | Urology PodcastGU Cast | Urology Podcast"This has opened our minds to what might work"Nurses are stepping up to support cancer patients during the COVID pandemic. Today we hear from Liz Medhurst, Urology Nurse Consultant at Peter MacCallum Cancer Centre in Melbourne, in discussion with Louisa Fleure, Lead GU Oncology Clinical Nurse Specialist at Guy's & St Thomas' NHS Foundation Trust in London. Louisa and Liz discuss some of teh innovative ways we can support cancer patients during these strange times. Hosted as ever by Declan Murphy and Renu Eapen. 2020-04-2730 minGU Cast | Urology PodcastGU Cast | Urology PodcastTestis cancer and Telehealth - business as usual in TorontoToday we are joined by Dr Rob Hamilton, Urologist at Princess Margaret Hospital in Toronto, and world-leading testis cancer specialist. Rob has been running a randomised trial of telehealth surveillance for testis cancer patients so has some great insights and advice for the rest of us. We also discuss his interest in testis cancer biomarkers and robotic surgery for retroperitoneal testicular cancer. Declan Murphy and Renu Eapen are joined again by Dr Ben Tran, Medical Oncologist at Peter Mac who knows Rob from his time doing a Fellowship at Princess Margaret. 2020-04-2129 minGU Cast | Urology PodcastGU Cast | Urology PodcastPCF Prostate Cancer Global Journal Club - PSMA PET/CT | GU Cast special episodeThanks to Dr Howard Soule and our friends at the Prostate Cancer Foundation in the USA, we are delighted to post this GU Cast special episode on PSMA PET/CT. PCF today hosted their first PCF Global Journal Club Webinar, focussing on PSMA PET/CT. Professor Michael Hofman presented an overview of the proPSMA trial recently published in the Lancet, with a lively panel discussion and questions from the global audience of almost 300 active participants. Join Howard, Michael, and special guests Prof Caroline Moore, Prof Jeremie Calais, Prof Scott Williams, Dr Kirsten Greene, and GU Cast host, Prof Declan...2020-04-161h 13GU Cast | Urology PodcastGU Cast | Urology PodcastBladder cancer and COVID - San Francisco perspectivesDr SIma Porten, Urologist at the University of California San Francisco, joins GU Cast to discuss the management of bladder cancer during the COVID pandemic. Huge challenges balancing risks of treatment vs risks of disease progression. Regular hosts Declan Murphy and Renu Eapen are joined by Dr Ben Tran, medical oncologist at Peter MacCallum Cancer Centre, Melbourne 2020-04-0929 minGU Cast | Urology PodcastGU Cast | Urology PodcastKidney cancer and COVID | Live to LondonDr Ben Challacombe, Urologist at Guy's & St Thomas' NHS Foundation Trust, & Chair of BAUS Oncology, joins us on GU Cast to discuss life in London as COVID nears its peak. Ben and the BAUS Oncology Committee released guidelines on the management of renal cancer a few days ago and he joins Declan Murphy, Renu Eapen, and Daniel Moon to discuss these. 2020-04-0733 minGU Cast | Urology PodcastGU Cast | Urology Podcast"It's ok to wait" - Italian perspectives on prostate cancer in COVID timesProfessor Alberto Briganti from San Raffaele University in Milan joins us for this episode of GU Chat. Today we focus on the challenges of managing localised prostate cancer during the COVID crisis. Amazing perspectives from the North of Italy. Regular hosts Declan Murphy and Renu Eapen are also joined this week by Dr Daniel Moon, Urologist at Peter MacCallum Cancer Centre. 2020-04-0131 minGU Cast | Urology PodcastGU Cast | Urology PodcastPSMA trumps conventional imaging - proPSMA discussionProfessor Declan Murphy and Dr Renu Eapen host the launch episode of GU Cast, a podcast focussing on GU cancers, from the team at Peter MacCallum Cancer Centre in Melbourne. Today our guest is Professor Michael Hofman, who discusses the proPSMA trial, published in The Lancet the week. Professor Caroline Moore from University College London joins us to comment. 2020-03-2634 min